Updated on 2025/06/09

Information

 

写真a

 
ushijima yasuhiro
 
Organization
Faculty of Medical Sciences Department of Clinical Medicine Associate Professor
Graduate School of Medical Sciences Department of Medical Sciences(Concurrent)
Graduate School of Medical Sciences Department of Medicine(Concurrent)
School of Medicine Department of Medicine(Concurrent)
Title
Associate Professor
Contact information
メールアドレス
Tel
0926425695
Profile
九州大学大学院医学研究院臨床放射線科の一員として、診療、教育、研究に携わる (診療) 1 当院の日常診療で撮像される腹部領域のCT・MRI・超音波検査の読影とレポート作成を行っている。 2 腹部領域の画像診断やIVRにおいて、各科からのコンサルトへの対応や各科との合同カンファレンスへの参加を行っている。 3 肝細胞癌の経血管的治療(血管塞栓術や動注リザーバー留置術)、肝動脈・門脈造影下CT、劇症肝炎や急性膵炎に対する動注カテーテル留置、経皮経肝的門脈塞栓術、血管奇形に対する塞栓術、骨盤内動注療法、腹部領域の救急疾患に対する緊急止血術、静脈サンプリング、診断などの血管造影を行っている。 4 CTや超音波を利用して、悪性腫瘍を中心とした生検や膿瘍に対するドレナージを行っている。 5 類骨骨腫や腎細胞癌、肝悪性腫瘍に対し、凍結療法やラジオ波焼却術を行っている。 6 週1回、放射線科外来で診療を行っている。通常の診療に加え、検査法に関する支持や、IVRの検査・治療内容について詳しい説明を行っている。 7 副病棟医長、外来医長、病棟医長、副医局長、医局長として、医局の運営に貢献している。 8 大動脈ステント留置後のエンドリークに対する、経皮的塞栓術の診療と研究を行っている 9 診療副科長として、診療の管理・運営を行っている (教育) 1 医学部学生、研修医、臨床大学院生に対し、腹部領域のCT・MRI・超音波検査などの画総診断の教育、レポート作成の指導を行っている。 2 医学部学生、研修医、臨床大学院生に対し、vascular IVR、non-vascular IVRの教育、手技の指導を行っている。 (研究) 1 肝細胞癌の血管内治療における回転DSAの有用性についての研究を行っている。 2 劇症肝炎に対するステロイド肝動注療法におけるカテーテル留置術の安全性や有効性についての研究を行っている 3 劇症肝炎に対するステロイド肝動注療法における肝臓の画像所見についての研究を行っている 4 腹部領域の緊急止血術の安全性、有用性についての研究をおこなっている 5 血管内治療において必要とされる腹部血管の解剖や変異を明らかにする研究を行っている 6 腎細胞癌に対する凍結療法の有効性に対する研究を行っている 7 大動脈ステント留置後のエンドリークに対する塞栓術に対する研究を行っている 8 頸椎病変にCTガイド下生検に対する有効性・安全性に対する研究を行っている 9 腎細胞癌に対する凍結療法前に施行するリピオドールマーキングの有用性についての研究を行っている 10 続発性腎細胞癌に対する凍結療法の治療成績・有用性についての研究を行っている 11 腎細胞癌に対する凍結療法におけるCTガイド下生検の有用性についての研究を行っている 13 高齢者の腎細胞癌に対する凍結療法後の治療経過についての研究を行っている 14 結節性硬化症に生じた腎血管筋脂肪種に対するCTガイド下凍結療法の有用性についての研究を行っている 15 Von-Hippel-Lindu病患者に生じた腎細胞癌に対する凍結療法の治療成績・有用性についての研究を行っている
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Degree

  • Ph.D in Medicine

Research Interests・Research Keywords

  • Research theme: Imaging diagnosis in the abdomen Interventional radiology Endovascular therapy Radiofrequency ablation Cryoablation Percutaneous embolization for endoleak CT guided biopsy for cervical spinal lesion

    Keyword: Imaging diagnosis in the abdomen, interventional radiology, Endovascular therapy, Radiofrequency ablation, Cryoablation, Percutaneous embolization

    Research period: 2011.4

Awards

  • Cum Laude, RSNA 2024

    2024.12   105th Scientific Assembly and Annual Meeting of Radiological Society of North America   CT-guided cryoablation for renal cell carcinoma: pitfalls, and tips to ensure accuracy and safety

    Yasuhiro Ushijima, Daisuke Okamoto, Nobuhiro Fujita, Keisuke Ishimatsu, Kousuke Tabata, Satoshi Makise and Kousei Ishigami

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    Award type:Award from international society, conference, symposium, etc.  Country:United States

    腎細胞癌に対するCTガイド下凍結療法についてまとめた教育展示

  • Certificated of featured abstract

    2021.5   第50回日本IVR学会総会  

  • 第71回日本医学放射線学会総会CyPos賞Bonze medal

    2012.4   日本医学放射線学会   腎盂癌の検出における拡散強調像の有用性

Papers

  • 特集 膵・消化管神経内分泌腫瘍の診療アップデート 2.膵神経内分泌腫瘍の画像診断 -US,CT,MRI

    田畑 公佑, 藤田 展宏, 牛島 泰宏, 岡本 大佑, 石松 慶祐, 石神 康生

    臨床消化器内科   40 ( 5 )   513 - 518   2025.4   ISSN:0911601X eISSN:24332488

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    DOI: 10.19020/cg.0000003434

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  • Value of gadoxetic acid-enhanced MR imaging for preoperative prediction of future liver regeneration after hemihepatectomy(タイトル和訳中)

    Fujita Nobuhiro, Ushijima Yasuhiro, Itoyama Masahiro, Okamoto Daisuke, Ishimatsu Keisuke, Tabata Kosuke, Itoh Shinji, Ishigami Kousei

    Japanese Journal of Radiology   42 ( 12 )   1439 - 1447   2024.12   ISSN:1867-1071

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  • Value of gadoxetic acid-enhanced MR imaging for preoperative prediction of future liver regeneration after hemihepatectomy

    Fujita, N; Ushijima, Y; Itoyama, M; Okamoto, D; Ishimatsu, K; Tabata, K; Itoh, S; Ishigami, K

    JAPANESE JOURNAL OF RADIOLOGY   42 ( 12 )   1439 - 1447   2024.12   ISSN:1867-1071 eISSN:1867-108X

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    Purpose: Liver resection is currently considered the most effective treatment for patients with liver cancer. To the best of our knowledge, no study has investigated the association between gadoxetic acid-enhanced magnetic resonance imaging (MRI) findings and liver regeneration in patients who underwent hemihepatectomy. We aimed to clarify the relationship between the signal intensity (SI) of the liver parenchyma on gadoxetic acid-enhanced MRI and the degree of liver regeneration in patients who underwent hemihepatectomy. Materials and methods: Forty-one patients who underwent gadoxetic acid-enhanced MRI before hemihepatectomy were enrolled. We calculated the liver-to-erector spinae muscle SI ratio (LMR) in the hepatobiliary phase and the precontrast images. ΔLMR was calculated using the following equation: ΔLMR = (LMR in the hepatobiliary phase−LMR in the precontrast image)/LMR in the precontrast image. The preoperative and postoperative remnant liver volumes (LVs) were calculated using CT volumetry. We calculated the resection rate (RR) and liver regeneration index (LRI) using the following formulas: RR = Resected LV/Total LV × 100 and LRI = (postoperative remnant LV−preoperative remnant LV)/preoperative remnant LV × 100. The relationships among LRI, imaging, and clinicopathological factors were analyzed. Results: Univariate analysis showed RR and ΔLMR showed a positive correlation with LRI (ρ = 0.4133, p = 0.0072 and ρ = 0.7773, p < 0.001, respectively). Spleen volume showed a negative correlation with LRI (ρ = −0.3138, p = 0.0486). Stepwise multiple regression analysis showed ΔLMR and RR were independently correlated with LRI (β coefficient = 44.8771, p = 0.0198 and β coefficient = 1.9653, p < 0.001, respectively). Conclusion: ΔLMR may serve as a preoperative predictor of liver regeneration in patients undergoing hemihepatectomy.

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  • 特集 肝胆膵のcommon diseaseにみる非典型的画像所見 膵漿液性嚢胞腫瘍(SCN)

    牧瀬 智, 藤田 展宏, 中山 智博, 牛島 泰宏, 岡本 大佑, 石松 慶祐, 田畑 公佑, 石神 康生

    画像診断   44 ( 12 )   1202 - 1208   2024.9   ISSN:02850524 eISSN:24321281

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    Publisher:学研メディカル秀潤社  

    DOI: 10.15105/gz.0000005810

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  • Multiparametric assessment of microvascular invasion in hepatocellular carcinoma using gadoxetic acid-enhanced MRI ( vol 49 , pg 1467, 2024)

    Fujita, N; Ushijima, Y; Ishimatsu, K; Okamoto, D; Wada, N; Takao, S; Murayama, R; Itoyama, M; Harada, N; Maehara, J; Oda, Y; Ishigami, K; Nishie, A

    ABDOMINAL RADIOLOGY   49 ( 7 )   2559 - 2560   2024.7   ISSN:2366-004X eISSN:2366-0058

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    In this paper, references from 25 to 40 are incorrect in the original publication. The correct references are given below: Bastati N, Wibmer A, Tamandl D, et al. (2016) Assessment of Orthotopic Liver Transplant Graft Survival on Gadoxetic Acid-Enhanced Magnetic Resonance Imaging Using Qualitative and Quantitative Parameters. Invest Radiol 51:728–734. Bastati N, Beer L, Mandorfer M, et al. (2020) Does the Functional Liver Imaging Score Derived from Gadoxetic Acid-enhanced MRI Predict Outcomes in Chronic Liver Disease Radiology 294:98–107. Torbenson MS, Ng IOL, Park YN, Roncalli M, Sakamoto M (2019). Hepatocellular carcinoma. In: WHO classification of Tumors Editorial Board. Digestive system tumours. Lyon (France): Internal Agency for Research on Cancer: pp229-239. Roayaie S, Blume IN, Thung SN et al. (2009) A system of classifying microvascular invasion to predict outcome after resection in patients with hepatocellular carcinoma. Gastroenterology 137:850–855. Tomimaru Y, Sasaki Y, Yamada T et al. (2006) Fibrosis in non-cancerous tissue is the unique prognostic factor for primary hepatocellular carcinoma without hepatitis B or C viral infection. World J Surg 30:1729–1735. Esnaola NF, Lauwers GY, Mirza NQ et al. (2002) Predictors of microvascular invasion in patients with hepatocellular carcinoma who are candidates for orthotopic liver transplantation. J Gastrointest Surg 6:224–232; discussion 232. Ng IO, Lai EC, Ng MM, Fan ST (1992) Tumor encapsulation in hepatocellular carcinoma. A pathologic study of 189 cases. Cancer 70:45–49. Fujita N, Nishie A, Asayama Y et al. (2020) Quantitative evaluation of liver function and pathology with hepatocyte fraction on Gadoxetic acid-enhanced MR imaging Magn Reson Imaging 72:125–129. Rosenkrantz AB, Oei M, Babb JS, Niver BE, Taouli B (2011) Diffusion-weighted imaging of the abdomen at 3.0 tesla: image quality and apparent diffusion coefficient reproducibility compared with 1.5 tesla. J Magn Reson Imaging 33:128–135. Tang Y, Wang H, Wang Y, et al. (2016) Quantitative comparison of MR diffusion-weighted imaging for liver focal lesions between 3.0T and 1.5T: Regions of interest of the minimum-spot ADC, the largest possible solid part, and the maximum diameter in lesions J Magn Reson Imaging 44:1320–1329. Nishie A, Tajima T, Asayama Y et al. (2011) Diagnostic performance of apparent diffusion coefficient for predicting histological grade of hepatocellular carcinoma. Eur J Radiol. 80:e29-33. Yokoo T, Masaki N, Parikh ND, Lane BF et al. (2023) Multicenter validation of abbreviated MRI for detecting early-stage hepatocellular carcinoma. Radiology. 307:e220917. Ehman EC, Behr SC, Umetsu SE et al. (2016) Rate of observation and inter-observer agreement for LI-RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas. Abdom Radiol (NY) 41:963–969. Matsui O, Kobayashi S, Sanada J et al. (2011) Hepatocelluar nodules in liver cirrhosis: hemodynamic evaluation (angiography-assisted CT) with special reference to multistep hepatocarcinogenesis. Abdom Imaging 36:264–272. Min JH, Lee MW, Park HS et al. (2020) Interobserver Variability and Diagnostic Performance of Gadoxetic Acid-enhanced MRI for Predicting Microvascular Invasion in Hepatocellular Carcinoma. Radiology 297: 573–581. Fan L, Mac MT, Frishberg DP et al. (2010) Interobserver and intraobserver variability in evaluating vascular invasion in hepatocellular carcinoma. J Gastroenterol Hepatol 25: 1556–1561. The original article has been updated.

    DOI: 10.1007/s00261-024-04466-7

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  • Safety and clinical contribution of computed tomography-guided biopsy for cervical spine lesion

    Okamoto, D; Ushijima, Y; Fujita, N; Ishimatsu, K; Murayama, R; Itoyama, M; Ishigami, K

    MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES   33 ( 3 )   171 - 175   2024.6   ISSN:1364-5706 eISSN:1365-2931

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    Introduction: The purpose is to clarify the safety and clinical contribution of computed tomography (CT)-guided percutaneous needle-biopsy for patients with cervical spine lesion. Material and methods: Between June 2015 and August 2022, CT-guided percutaneous needle biopsies were performed for 15 cervical spine lesions of 15 patients (8 male, 7 female; 2–81 years old). The technical success, clinical contribution, and safety were evaluated. Technical success was defined as the completion of the biopsy procedure. Clinical contribution was defined as any contribution to the therapeutic strategy. Safety was assessed by the Common Terminology Criteria for Adverse Events, version 5.0. Results: The technical success rate was 100%. In all 15 patients, nontarget organs (e.g., major vessels, spinal cord) could be avoided. The post-biopsy histological diagnoses were myeloma (n = 2), metastatic adenocarcinoma (n = 2), chordoma (n = 2), Langerhans cell histiocytosis (n = 3), and one case each of malignant lymphoma, schwannoma, pyogenic spondylitis, non-pyogenic spondylitis, degenerative change, and non-pathological fracture. All of these diagnoses contributed to the therapeutic strategy decisions. One case of grade 2 pain was observed, but no complications with grade 3 or more were observed during or after the biopsies. Conclusion: CT-guided percutaneous needle biopsies for cervical spine lesions were safe and clinically beneficial.

    DOI: 10.1080/13645706.2024.2311720

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  • Multiparametric assessment of microvascular invasion in hepatocellular carcinoma using gadoxetic acid-enhanced MRI

    Fujita, N; Ushijima, Y; Ishimatsu, K; Okamoto, D; Wada, N; Takao, S; Murayama, R; Itoyama, M; Harada, N; Maehara, J; Oda, Y; Ishigami, K; Nishie, A

    ABDOMINAL RADIOLOGY   49 ( 5 )   1467 - 1478   2024.5   ISSN:2366-004X eISSN:2366-0058

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    Purpose: To elucidate how precisely microvascular invasion (MVI) in hepatocellular carcinoma (HCC) can be predicted using multiparametric assessment of gadoxetic acid-enhanced MRI. Methods: In this retrospective single-center study, patients who underwent liver resection or transplantation of HCC were evaluated. Data obtained in patients who underwent liver resection were used as the training set. Nine kinds of MR findings for predicting MVI were compared between HCCs with and without MVI by univariate analysis, followed by multiple logistic regression analysis. Using significant findings, a predictive formula for diagnosing MVI was obtained. The diagnostic performance of the formula was investigated in patients who underwent liver resection (validation set 1) and in patients who underwent liver transplantation (validation set 2) using a receiver operating characteristic curve analysis. The area under the curves (AUCs) of these three groups were compared. Results: A total of 345 patients with 356 HCCs were selected for analysis. Tumor diameter (D) (P = 0.021), tumor washout (TW) (P < 0.01), and peritumoral hypointensity in the hepatobiliary phase (PHH) (P < 0.01) were significantly associated with MVI after multivariate analysis. The AUCs for predicting MVI of the predictive formula were as follows: training set, 0.88 (95% confidence interval (CI) 0.82,0.93); validation set 1, 0.81 (95% CI 0.73,0.87); validation set 2, 0.67 (95% CI 0.51,0.80). The AUCs were not significantly different among three groups (training set vs validation set 1; P = 0.15, training set vs validation set 2; P = 0.09, validation set 1 vs validation set 2; P = 0.29, respectively). Conclusion: Our multiparametric assessment of gadoxetic acid-enhanced MRI performed quite precisely and with good reproducibility for predicting MVI. Graphical abstract: (Figure presented.)

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  • Effect of lipiodol marking before CT-guided cryoablation on the outcome of sporadic renal cell carcinoma. Reviewed International journal

    Ushijima Y, Okamoto D, Fujita N, Ishimatsu K, Wada N, Takao S, Murayama R, Itoyama M, Ishigami K.

    Diagn Interv Radiol.   30   117 - 123   2024.3

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.4274/dir.2023.232381.

  • Effect of lipiodol marking before CT-guided cryoablation on the outcome of sporadic renal cell carcinoma

    Ushijima, Y; Okamoto, D; Fujita, N; Ishimatsu, K; Wada, N; Takao, S; Murayama, R; Itoyama, M; Ishigami, K

    DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY   30 ( 2 )   117 - 123   2024.3   ISSN:1305-3612

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    PURPOSE This retrospective study evaluates the impact of preoperative lipiodol marking on the outcomes of computed tomography (CT)-guided cryoablation for histologically diagnosed sporadic renal cell carcinoma (RCC). METHODS This study analyzed the data of 173 patients who underwent CT-guided cryoablation for histologi-cally proven sporadic RCC at a single institution between April 2014 and December 2020. The local control rate (LCR), recurrence-free survival rate (RFSR), overall survival rate (OSR), changes in renal function, and complications in patients with (n = 85) and without (n = 88) preoperative lipiodol marking were compared. RESULTS The 5-year LCR and 5-year RFSR were significantly higher in patients with lipiodol marking (97.51% and 93.84%, respectively) than in those without (72.38% and 68.10%, respectively) (P value <0.01, log-rank test). There were no significant differences between the two groups regarding the 5-year OSR (97.50% vs. 86.82%) or the deterioration in chronic kidney disease stage (12.70% vs. 16.43%). Grade ≥3 complications occurred in patients with lipiodol marking (n = 2, retroperitoneal hemato-ma and cerebral infarction in 1 patient each) and without (n = 5; urinary fistula in 2, colonic perfo-ration in 2, urinary infection in 1). CONCLUSION Lipiodol marking before CT-guided cryoablation for sporadic RCC is a feasible approach to improv-ing local control and RFS while mitigating the decline in renal function. Additionally, it may help reduce complications.

    DOI: 10.4274/dir.2023.232381

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  • エキスパートによるIVR症例集 片腎の腎門部に生じた腎細胞癌に対してCTガイド下経皮的凍結療法を施行し、良好な局所制御と腎機能温存が得られた1例

    牛島 泰宏, 岡本 大佑, 久保 雄一郎, 石松 慶祐, 藤田 展宏, 糸山 昌宏, 田畑 公佑, 石神 康生

    Rad Fan   22 ( 2 )   106 - 108   2024.1   ISSN:1348-3498

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    Language:Japanese   Publisher:(株)メディカルアイ  

    腎門部に生じた腎細胞癌は、標準治療である外科的切除では部分切除術が困難であることが多く、腎摘出術となると腎機能低下は避けられない。今回我々は、対側腎摘出後で片腎の腎門部に生じた腎細胞癌に対してCTガイド下経皮的凍結療法を施行し、良好な局所制御と腎機能温存が得られた症例を経験したので報告する。(著者抄録)

  • Diagnostic accuracy of percutaneous core biopsy before cryoablation for small-sized renal cell carcinoma

    Ushijima, Y; Nishie, A; Fujita, N; Kubo, Y; Ishimatsu, K; Ishigami, K

    DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY   29 ( 6 )   800 - 804   2023.11   ISSN:1305-3612

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    PURPOSE To retrospectively determine the diagnostic accuracy of a percutaneous core biopsy performed before cryoablation for small-sized renal cell carcinoma. METHODS In this study, 216 patients underwent a percutaneous core biopsy for 242 renal lesions suspected to be renal cell carcinoma on image findings before cryoablation at Kyushu University Hospital. We calculated the success rate of the histological diagnosis and investigated factors that may have contributed to the diagnostic success. Complications caused by the biopsy procedure were also evaluated. RESULTS The histological diagnosis was successful in 203 lesions (82.8%). The success rate of the histologi-cal diagnosis was 65.4% (34/52 cases) for tumors with a diameter of ≤15 mm and 88.9% (169/190 cases) for those >15 mm. Therefore, tumor diameter was a factor contributing to the histological diagnosis success rate in both univariate and multivariable analyses (P < 0.001). For lesions with a tumor diameter ≤15 mm, the histological diagnosis success rates increased from 50.0% to 76.2% in the presence of pre-lipiodol marking and to 85.7% when the biopsy procedure was performed separately from cryoablation; the latter was statistically significant (P = 0.039). Major complications that may have been caused by the biopsy procedure were grade 3 bleeding and tract seeding (one case each). CONCLUSION Percutaneous core biopsy in cryoablation for small-sized renal cell carcinoma had a high diagnostic rate and was safely performed. For lesions with a tumor diameter ≤15 mm, a separate biopsy procedure and pre-lipiodol marking may improve the diagnostic accuracy.

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  • Impact of portal-phase signal intensity of dynamic gadoxetic acid-enhanced magnetic resonance imaging in hepatocellular carcinoma. Reviewed International journal

    Tomino T, Itoh S, Okamoto D, Yoshiya S, Nagao Y, Harada N, Fujita N, Ushijima Y, Ishigami K, Yoshizumi T.

    J Hepatobiliary Pancreat Sci.   30 ( 9 )   1089 - 1097   2023.9

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    DOI: 10.1002/jhbp.1345.

  • Impact of portal-phase signal intensity of dynamic gadoxetic acid-enhanced magnetic resonance imaging in hepatocellular carcinoma

    Tomino, T; Itoh, S; Okamoto, D; Yoshiya, S; Nagao, Y; Harada, N; Fujita, N; Ushijima, Y; Ishigami, K; Yoshizumi, T

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   30 ( 9 )   1089 - 1097   2023.9   ISSN:1868-6974 eISSN:1868-6982

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    Language:English   Publisher:Journal of Hepato-Biliary-Pancreatic Sciences  

    Purpose: To evaluate the prognostic impact of dynamic gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) in patients with hepatocellular carcinoma (HCC). Methods: We retrospectively reviewed the data of 206 patients with HCC who underwent preoperative Gd-EOB-DTPA-enhanced MRI and hepatectomy and quantitatively evaluated the signal intensity ratio of the tumor to the surrounding liver tissue in the portal phase (SIRPP). We verified the survival rates and assessed the prognostic factors associated with overall survival (OS) and recurrence-free survival (RFS) using SIRPP. Results: Multivariate analysis revealed that the independent predictive factors for poorly-differentiated HCC were α-fetoprotein > 20 ng/mL (hazard ratio [HR]: 3.1909, 95% confidence interval [CI]: 1.3464–7.5622, p =.0084) and SIRPP ≤ 0.85 (HR: 3.7155, 95% CI: 1.521–9.076, p =.004). The 5-year OS and RFS rates in the high and low SIRPP groups were 83.2 and 52.1%, respectively (p <.0001) and 49.7 and 18.5%, respectively (p =.0003). Multivariate analysis revealed that SIRPP ≤ 0.68 was an independent prognostic factor related to OS (HR: 4.4537, 95% CI: 1.6581–11.9626, p =.003). Conclusion: The SIRPP of preoperative Gd-EOB-DTPA-enhanced MRI might predict the histological differentiation and prognosis of HCC.

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  • 肝細胞癌におけるダイナミックガドキセト酸造影MRIの門脈相信号強度の影響(Impact of portal-phase signal intensity of dynamic gadoxetic acid-enhanced magnetic resonance imaging in hepatocellular carcinoma)

    Tomino Takahiro, Itoh Shinji, Okamoto Daisuke, Yoshiya Shohei, Nagao Yoshihiro, Harada Noboru, Fujita Nobuhiro, Ushijima Yasuhiro, Ishigami Kousei, Yoshizumi Tomoharu

    Journal of Hepato-Biliary-Pancreatic Sciences   30 ( 9 )   1089 - 1097   2023.9   ISSN:1868-6974

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    肝細胞癌(HCC)患者におけるダイナミックGd-EOB-DTPA造影MRI所見と予後との関連を検討した。Gd-EOB-DTPA造影MRIの施行後に肝切除を受けたHCC患者206例を対象に後ろ向きレビューを行い、門脈相における肝組織周囲に対する腫瘍の信号強度比(SIRPP)を算出し、全生存率(OS)、無再発生存率(RFS)との関連を評価した。58例(28.2%)に未分化成分が検出され、多変量解析では未分化型HCCの独立予測因子としてAFP 20ng/mL超およびSIRPP 0.85以下が抽出された。患者生存を評価したROC解析ではSIRPPのカットオフ値は0.68と算出され、この値をもとにSIRPP高値群166例とSIRPP低値群40例に分類すると、高値群にはF3またはF4の組織学的肝硬変が多く、SIRPP低値群にはBCLCステージBまたはC、腹腔鏡下肝切除の施行、未分化型HCC、被膜形成、顕微的被膜浸潤・脈管浸潤・胆管浸潤を多く認めた。また、AFP、AFP-L3、DCP、手術時間、術中出血量、腫瘍サイズはSIRPP低値群の方が有意に高値を示しており、5年OSはSIRPP高値群が83.2%、低値群が52.1%、5年RFSはSIRPP高値群が49.7%、低値群が18.5%と有意差が認められた。多変量解析ではOSの独立予測因子としてDCP 100mAU/mL以上、SIRPP 0.68以下、RFSの独立予測因子として腫瘍数2個以上が示された。ダイナミックGd-EOB-DTPA造影MRIによりHCCの組織学的分化度と予後を予測できうると思われた。

  • Clinical association between intraoperative indocyanine green fluorescence imaging pattern, preoperative Gd-EOB-DTPA-enhanced magnetic resonance imaging findings, and histological differentiation in hepatocellular carcinoma. Reviewed International journal

    Tomino T, Itoh S, Fujita N, Okamoto D, Nakayama Y, Toshida K, Tomiyama T, Tsutsui Y, Kosai Y, Kurihara T, Nagao Y, Morita K, Harada N, Ushijima Y, Kohashi K, Ishigami K, Oda Y, Yoshizumi T.

    Hepatol Res.   53 ( 8 )   723 - 736   2023.8

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    DOI: 10.1111/hepr.13902.

  • 肝細胞癌における術中インドシアニングリーン蛍光画像パターン、術前Gd-EOB-DTPA造影MRI所見、組織学的分化の臨床的関連性(Clinical association between intraoperative indocyanine green fluorescence imaging pattern, preoperative Gd-EOB-DTPA-enhanced magnetic resonance imaging findings, and histological differentiation in hepatocellular carcinoma)

    Tomino Takahiro, Itoh Shinji, Fujita Nobuhiro, Okamoto Daisuke, Nakayama Yuki, Toshida Katsuya, Tomiyama Takahiro, Tsutsui Yuriko, Kosai Yukiko, Kurihara Takeshi, Nagao Yoshihiro, Morita Kazutoyo, Harada Noboru, Ushijima Yasuhiro, Kohashi Kenichi, Ishigami Kousei, Oda Yoshinao, Yoshizumi Tomoharu

    Hepatology Research   53 ( 8 )   723 - 736   2023.8   ISSN:1386-6346

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    日本の単一施設の肝細胞癌(HCC)患者64例の腫瘍データ80件を後ろ向きに評価し、術中インドシアニングリーン(ICG)蛍光画像(FI)パターン、術前Gd-EOB-DTPA造影MRI所見、術前MRI拡散強調画像(DWI)、組織学的分化の臨床的関連性を評価した。ICG FIでrim陽性であった患者では、rim陰性患者に比べて低分化HCC率とGd-EOB-DTPA造影MRI肝胆道相(HBP)の低信号率が有意に高く、Gd-EOB-DTPA造影MRI門脈相の周囲肝組織に対する腫瘍のシグナル強度比(SIRPP)とMRI DWI見かけの拡散係数(ADC)が有意に低値であった。ICG FIで癌性に分類された患者は、非癌性患者に比べて中分化HCC率、Gd-EOB-DTPA造影MRI HBPの高信号率とSIRPP、MRI DWI ADCが有意に高値であった。多変量解析において、SIRPP低値、ADC低値、HBPの低信号率はrim陽性HCCの有意な予測因子であり、SIRPP高値、ADC高値、HBPの高信号率は癌性HCCの有意な予測因子であった。

  • Clinical association between intraoperative indocyanine green fluorescence imaging pattern, preoperative Gd-EOB-DTPA-enhanced magnetic resonance imaging findings, and histological differentiation in hepatocellular carcinoma

    Tomino, T; Itoh, S; Fujita, N; Okamoto, D; Nakayama, Y; Toshida, K; Tomiyama, T; Tsutsui, Y; Kosai, Y; Kurihara, T; Nagao, Y; Morita, K; Harada, N; Ushijima, Y; Kohashi, K; Ishigami, K; Oda, Y; Yoshizumi, T

    HEPATOLOGY RESEARCH   53 ( 8 )   723 - 736   2023.8   ISSN:1386-6346 eISSN:1872-034X

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    Aim: We aimed to evaluate the association between the intraoperative indocyanine green (ICG) fluorescence imaging (FI) pattern, preoperative magnetic resonance imaging (MRI) findings using gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA), preoperative diffusion-weighted imaging (DWI) of MRI, and histological differentiation of hepatocellular carcinoma (HCC). Methods: We retrospectively reviewed the data for 80 tumors of 64 patients. Intraoperative ICG FI patterns were classified into cancerous or rim-positive type. We evaluated the signal intensity ratio of the tumor and the surrounding liver tissue in the portal phase (SIRPP) and intensity in the hepatobiliary phase (HBP) of Gd-EOB-DTPA-enhanced MRI, the apparent diffusion coefficient (ADC) in the DWI of MRI, and clinicopathologic factors. Results: In the rim-positive group, the rate of poorly differentiated HCC and hypointensity type in HBP were significantly higher, and SIRPP and ADC were significantly lower than the rim-negative group. In the cancerous group, the rate of well or moderately differentiated HCC and hyperintensity type in HBP, SIRPP, and ADC were significantly higher than the noncancerous group. Multivariate analysis identified low SIRPP, low ADC, and hypointensity type in HBP as the significant predictive factors for rim-positive HCC and high SIRPP, high ADC, and hyperintensity type in HBP as the significant predictive factors for cancerous HCC. The positive rate of programmed cell death 1-ligand 1 and vessels that encapsulate tumor clusters status of the rim-positive HCC and HCC with low SIRPP were significantly higher than the control group. Conclusions: The intraoperative ICG FI pattern of HCC closely correlated with histological differentiation, preoperative SIRPP and intensity type in the Gd-EOB-DTPA MRI, and preoperative ADC in the DWI of MRI.

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  • 症例 ポリープ状の形態を呈した腎細胞癌胆嚢転移の1例

    安部 時子, 藤田 展宏, 牛島 泰宏, 石松 慶祐, 門司 恵介, 古賀 裕, 石神 康生

    臨床放射線   68 ( 5 )   487 - 491   2023.5   ISSN:00099252

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    DOI: 10.18888/rp.0000002332

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  • Extracellular volume fraction determined by dual-layer spectral detector CT: Possible role in predicting the efficacy of preoperative neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma. Invited Reviewed International journal

    Fujita N, Ushijima Y, Itoyama M, Okamoto D, Ishimatsu K, Wada N, Takao S, Murayama R, Fujimori N, Nakata K, Nakamura M, Yamamoto T, Oda Y, Ishigami K.

    Eur J Radiol.   162   2023.5

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    DOI: 10.1016/j.ejrad.2023.110756.

  • Extracellular volume fraction determined by dual-layer spectral detector CT: Possible role in predicting the efficacy of preoperative neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma

    Fujita, N; Ushijima, Y; Itoyama, M; Okamoto, D; Ishimatsu, K; Wada, N; Takao, S; Murayama, R; Fujimori, N; Nakata, K; Nakamura, M; Yamamoto, T; Oda, Y; Ishigami, K

    EUROPEAN JOURNAL OF RADIOLOGY   162   110756   2023.5   ISSN:0720-048X eISSN:1872-7727

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    Purpose: To clarify the relationship between extracellular volume (ECV) measured by dual-energy CT (DECT) and efficacy of preoperative neoadjuvant chemotherapy (NAC) in patients with pancreatic ductal adenocarcinoma (PDAC), as compared with single-energy CT (SECT). Methods: We enrolled 67 patients with PDAC who underwent dynamic contrast-enhanced CT with a dual-energy CT system prior to NAC. Attenuation values were measured on unenhanced and the equilibrium-phase 120-kVp equivalent CT images for PDAC and the aorta. ΔHU-tumor, ΔHU-tumor/ΔHU-aorta, and SECT-ECV were calculated. Iodine densities of the tumor and aorta were measured in the equilibrium phase, and DECT-ECV of the tumor was calculated. Response to NAC was evaluated and the correlation between imaging parameters and response to NAC was statistically assessed. Results: Tumor DECT-ECVs were significantly lower in the response group (n = 7) than in the non-response group (n = 60), with most significant difference (p = 0.0104). DECT-ECV showed highest diagnostic value with an Az value of 0.798. When using the optimal cut off value of DECT-ECV (<26.0 %), sensitivity, specificity, accuracy, positive predictive value, and negative value for predicting response group were 71.4 %, 85.0 %, 83.6 %, 35.7 % and 96.2 %, respectively. Conclusion: PDAC with lower DECT-ECV can potentially show better response to NAC. DECT-ECV might be a useful biomarker for predicting response to NAC in patients with PDAC.

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  • 【腹部の最新画像情報2023】ポリープ状の形態を呈した腎細胞癌胆嚢転移の1例

    安部 時子, 藤田 展宏, 牛島 泰宏, 石松 慶祐, 門司 恵介, 古賀 裕, 石神 康生

    臨床放射線   68 ( 5 )   487 - 491   2023.5   ISSN:0009-9252

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    症例は50歳代男性で、腎細胞癌(淡明細胞癌)、骨転移の診断で化学療法施行中であったが、経過中のCTで胆嚢底部に増強される微小なポリープ状病変が出現し、経時的に増大した。病変は腹部MRI T2強調像で軽度高信号、T1強調像(in phase)で等信号を呈したが、out of phaseで信号低下はなく、拡散強調像では高信号で軽度の拡散制限を認めた。造影MRIでは動脈優位相で増強され、遅延相はwash outされた。胆嚢癌疑いで腹腔鏡下胆嚢摘出術を行い、腫瘤性病変(20mm大)の病理所見よりgrade 2の腎細胞癌(淡明細胞癌)の転移と診断された。後方視的にMRI所見を再検討した。その結果、chemical shift imagingで脂肪は認めないが、dynamic studyで早期濃染とwash outを呈しており、画像上は腎細胞癌の胆嚢転移を疑う所見であった。

  • 手術症例報告 転移性肝血管肉腫破裂による腹腔内出血に対して術前IVR・左肝切除術を行い救命した1例

    今村 柾紀, 井手野 昇, 伊東 守, 牛島 泰宏, 小田 義直, 中村 雅史

    手術   77 ( 3 )   383 - 389   2023.3   ISSN:00374423

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    DOI: 10.18888/op.0000003205

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  • Transcatheter arterial steroid injection therapy improves the prognosis of patients with acute liver failure

    Kuwano, A; Okui, T; Kohjima, M; Kurokawa, M; Goya, T; Tanaka, M; Aoyagi, T; Takahashi, M; Imoto, K; Tashiro, S; Suzuki, H; Fujita, N; Ushijima, Y; Ishigami, K; Tokunaga, S; Kato, M; Ogawa, Y

    MEDICINE   102 ( 10 )   e33090   2023.3   ISSN:0025-7974 eISSN:1536-5964

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    Acute liver failure (ALF) is a disorder defined by coagulopathy and encephalopathy with a poor prognosis. No effective therapies have been established except for liver transplantation. We previously reported a subgroup of patients with acute liver injury who developed microcirculatory disturbance. We also established and reported transcatheter arterial steroid injection therapy (TASIT) as a new treatment of ALF. Here, we analyze the effectiveness of TASIT in a larger cohort and evaluate the impact on ALF patients with or without microcirculatory disturbance. We conducted a single-center retrospective study to evaluate the effectiveness of TASIT in patients with ALF admitted at Kyushu University Hospital between January 2005 and March 2018. TASIT is performed by injecting methylprednisolone via the proper hepatic artery for 3 days. One hundred ninety-4 patients with ALF were enrolled and analyzed in this study. Of the 87 patients given TASIT, 71 (81.6%) recovered without any complications and 16 (18.4%) died or underwent liver transplantation. Of the 107 patients not administered TASIT, 77 (72.0%) recovered and 30 (28.0%) progressed to irreversible liver failure. In the high-lactate dehydrogenase subgroup, 52 (86.7%) of the 60 patients with TASIT recovered, and the survival rate was significantly higher than that in patients who did not receive TASIT. Multivariate regression analysis revealed that the TASIT procedure was one of the significant prognostic factors in the high-lactate dehydrogenase subgroup and was significantly associated with prothrombin activity percentage improvement. TASIT is an effective treatment for patients with ALF, especially in those with microcirculatory disturbance.

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  • Transcatheter arterial steroid injection therapy improves the prognosis of patients with acute liver failure. Reviewed International journal

    Kuwano A, Okui T, Kohjima M, Kurokawa M, Goya T, Tanaka M, Aoyagi T, Takahashi M, Imoto K, Tashiro S, Suzuki H, Fujita N, Ushijima Y, Ishigami K, Tokunaga S, Kato M, Ogawa Y.

    Medicine (Baltimore)   102 ( 10 )   e33090   2023.3

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    DOI: 10.1097/MD.0000000000033090.

  • 転移性肝血管肉腫破裂による腹腔内出血に対して術前IVR・左肝切除術を行い救命した1例

    今村 柾紀, 井手野 昇, 伊東 守, 牛島 泰宏, 小田 義直, 中村 雅史

    手術   77 ( 3 )   383 - 389   2023.3   ISSN:0037-4423

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    32歳女性。既往として右乳房血管肉腫に対する部分切除が行われた。今回、上腹部痛を主訴に当院へ救急搬送となった。入院後、約6時間経過で血圧低下と貧血進行を認めたため、造影CTを行ったところ、転移性肝血管肉腫の破裂による腹腔内出血と診断された。TAEのみでは止血困難であることから、本症例は術前にIVRによる栄養血管を塞栓後、術中、中心静脈圧のコントロールと体外循環を視野に入れた静脈路確保が行われた。安全に左肝切除術を施行することができたことで、術後は合併症なく退院し、目下は全身化学療法が行われている。

  • Evaluation of the safety and effectiveness of cryoablation in the treatment of renal angiomyolipoma related to tuberous sclerosis complex: The Cryo-TSC.

    Kashiwagi, E; Hatano, T; Shimiz, K; Takamoto, A; Tomita, K; Osawa, T; Sakuhara, Y; Hongo, F; Hirota, T; Ushijima, Y; Asayama, Y; Miki, J; Kiyomi, F; Egawa, S; Nasu, Y; Shinohara, N; Ukimura, O; Nakano, S; Arai, Y; Eto, M

    JOURNAL OF CLINICAL ONCOLOGY   41   2023.2   ISSN:0732-183X eISSN:1527-7755

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  • Diagnostic accuracy of percutaneous core biopsy before cryoablation for small-sized renal cell carcinoma. Invited Reviewed International journal

    Ushijima Y, Nishie A, Fujita N, Kubo Y, Ishimatsu K, Ishigami K.

    Diagn Interv Radiol.   2022.12

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    DOI: 10.4274/dir.2022.221152.

  • A novel fast kilovoltage switching dual-energy computed tomography technique with deep learning: Utility for non-invasive assessments of liver fibrosis. Reviewed International journal

    Wada N, Fujita N, Ishimatsu K, Takao S, Yoshizumi T, Miyazaki Y, Oda Y, Nishie A, Ishigami K, Ushijima Y.

    Eur J Radiol   155   110461   2022.10

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    DOI: 10.1016/j.ejrad.2022.110461.

  • A novel fast kilovoltage switching dual-energy computed tomography technique with deep learning: Utility for non-invasive assessments of liver fibrosis

    Wada, N; Fujita, N; Ishimatsu, K; Takao, S; Yoshizumi, T; Miyazaki, Y; Oda, Y; Nishie, A; Ishigami, K; Ushijima, Y

    EUROPEAN JOURNAL OF RADIOLOGY   155   110461   2022.10   ISSN:0720-048X eISSN:1872-7727

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    Purpose: To investigate whether the iodine density of liver parenchyma in the equilibrium phase and extracellular volume fraction (ECV) measured by deep learning-based spectral computed tomography (CT) can enable noninvasive liver fibrosis staging. Method: We retrospectively analyzed 63 patients who underwent dynamic CT using deep learning-based spectral CT before a hepatectomy or liver transplantation. The iodine densities of the liver parenchyma (I-liver) and abdominal aorta (I-aorta) were independently measured by two radiologists using iodine density images at the equilibrium phase. The iodine-density ratio (I-ratio: I-liver/I-aorta) and CT-ECV were calculated. Spearman's rank correlation analysis was used to evaluate the relationship between the I-ratio or CT-ECV and liver fibrosis stage, and receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performances of the I-ratio and CT-ECV. Results: The I-ratio and CT-ECV showed significant positive correlations with liver fibrosis stage (ρ = 0.648, p < 0.0001 and ρ = 0.723, p < 0.0001, respectively). The areas under the ROC curve for the CT-ECV were 0.882 (F0 vs ≥ F1), 0.873 (≤F1 vs ≥ F2), 0.848 (≤F2 vs ≥ F3), and 0.891 (≤F3 vs F4). Conclusions: Deep learning-based spectral CT may be useful for noninvasive assessments of liver fibrosis.

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  • 再発子宮頸癌に対するペムブロリズマブ療法中に内腸骨動脈-S状結腸瘻を生じた一例(Arterio-enteric fistula in a patient with recurrent cervical cancer treated with pembrolizumab)

    永谷 優華, 八木 裕史, 久保 雄一郎, 牛島 泰宏, 堀 絵美子, 川上 穣, 友延 寛, 安武 伸子, 吉田 祥子, 小玉 敬亮, 安永 昌史, 大神 達寛, 小野山 一郎, 奥川 馨, 淺野間 和夫, 谷口 秀一, 嶋本 富博, 矢幡 秀昭, 石神 康生, 加藤 聖子

    宮崎県医師会医学会誌   46 ( 2 )   147 - 153   2022.9   ISSN:0389-8288

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    動脈-腸管瘻は消化管出血の原因としてはまれであるが,初発症状が致死性の大量出血の場合もある緊急性の高い疾患である。症例は44歳,9妊7産,子宮頸癌IB3期(扁平上皮癌)に対して広汎子宮全摘出術,両側付属器摘出術,術後補助療法として同時化学放射線療法を施行した。治療終了6ヵ月後に骨盤内再発を認め,全身化学療法を施行したが奏効しなかった。MSI検査の結果,MSI-highであったためペムブロリズマブ療法を開始した。腫瘍の著明な縮小を認め,4コース後の治療効果判定はPRであった。ペムブロリズマブ療法4コース目day7,当科入院中に突然,多量の下血,意識レベルの低下を認めた。緊急造影CTの結果,左内腸骨動脈からS状結腸への造影剤の漏出を認め,左内腸骨動脈-S状結腸瘻と診断した。直ちに左内腸骨動脈塞栓術を施行し止血した。発症から止血まで3時間の間に赤血球32単位,新鮮凍結血漿28単位,血小板10単位の輸血を要した。(著者抄録)

  • MR Prediction of Malignant Switch With the Cyst Fluid's T2 Value in Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Preliminary Study. Invited Reviewed International journal

    Takao S, Nishie A, Ushijima Y, Takayama Y, Morita K, Ishimatsu K, Koga Y, Mori Y, Akamine Y, Ishigami K.

    Anticancer Res.   42 ( 8 )   3895 - 3903   2022.8

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    DOI: 10.21873/anticanres.15883.

  • MR Prediction of Malignant Switch With the Cyst Fluid?s T2 Value in Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Preliminary Study

    Takao, S; Nishie, A; Ushijima, Y; Takayama, Y; Morita, K; Ishimatsu, K; Koga, Y; Mori, Y; Akamine, Y; Ishigami, K

    ANTICANCER RESEARCH   42 ( 8 )   3895 - 3903   2022.8   ISSN:0250-7005 eISSN:1791-7530

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    Background/Aim: We investigated whether the malignant switch of intraductal papillary mucinous neoplasm (IPMN) of the pancreas can be predicted by using the T1ρ, T2, and apparent diffusion coefficient (ADC) values of cyst fluid. Patients and Methods: We retrospectively analyzed the magnetic resonance (MR) images of 60 patients (26 males, 34 females, mean age 61 years) with branch-duct type and mixed-type IPMNs. The IPMNs were diagnosed clinically in 39 patients and histologically in 21 patients. The malignant potential was classified by MR imaging based on the international consensus guidelines for the management of IPMN established in 2017. Morphologically, 42 patients had "worrisome features" and three had "high-risk stigmata." Histologically, 14 lesions were diagnosed as low-grade dysplasia and seven as intermediate-grade dysplasia. The T1ρ, T2, and ADC values of cyst fluid in each patient's largest cyst were measured on the same slice, avoiding solid components. Spearman's rank correlation test was used to determine the correlation between the morphological malignancy and the T1ρ, T2, and ADC values. These values were also compared between the low-grade and intermediate-grade groups by Mann-Whitney U-test. Results: There was a significant rank-correlation between the morphological classification and T2 value (p=0.04). The T2 value of the intermediate-grade group was significantly higher than that of the low-grade group (p=0.03). No significant correlations were morphologically or histologically obtained regarding T1ρ and ADC. Conclusion: The T2 value of cyst fluid together with other MR-signs may be useful for predicting the malignant switch in IPMN of the pancreas.

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  • Differentiating Liver Hemangioma from Metastatic Tumor Using T2-enhanced Spin-echo Imaging with a Time-reversed Gradient-echo Sequence in the Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging. Reviewed International journal

    Takayama Y, Nishie A, Okamoto D, Fujita N, Asayama Y, Ushijima Y, Yoshizumi T, Yoneyama M, Ishigami K.

    Magn Reson Med Sci.   21 ( 3 )   445 - 457   2022.7

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    DOI: 10.2463/mrms.mp.2020-0151.

  • ガドキセト酸ナトリウム造影MRIでの肝細胞造影相にtime-reversed gradient-echoシーケンスを用いたT2-enhanced spin-echoイメージングによる肝血管腫と転移性腫瘍の鑑別(Differentiating Liver Hemangioma from Metastatic Tumor Using T2-enhanced Spin-echo Imaging with a Time-reversed Gradient-echo Sequence in the Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging)

    Takayama Yukihisa, Nishie Akihiro, Okamoto Daisuke, Fujita Nobuhiro, Asayama Yoshiki, Ushijima Yasuhiro, Yoshizumi Tomoharu, Yoneyama Masami, Ishigami Kousei

    Magnetic Resonance in Medical Sciences   21 ( 3 )   445 - 457   2022.7   ISSN:1347-3182

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    ガドキセト酸ナトリウム造影MRI(Gd-EOB-MRI)による肝細胞造影相(HBP)に、time-reversed gradient-echoシーケンスを用いたT2-enhanced spin-echoイメージング(T2FFEイメージング)を行い、肝血管腫と転移性腫瘍の鑑別能を比較した。2013年12月~2014年12月までの期間内に、著者らの所属する医療施設で肝腫瘍疑いのためGd-EOB-MRI検査が施行された患者のうち、選定基準を満たした患者61例(男性36例、女性25例、年齢32~83歳)に伴う肝血管腫37病巣と転移性腫瘍96病巣について後向きに評価した。その結果、3D fat-suppressed T2-weighted imaging(3D FS-T2WI)とT2FFEイメージング併用時のROC曲線下面積(AUC)は、3D FS-T2WIとDWIおよび見かけの拡散係数(ADC)併用時のAUCとの有意差はみられなかったが、病変の大きさに関係なくダイナミックGd-EOB-MRIのAUCに比べ有意に大きかった。以上より、Gd-EOB-MRIのHBPにおける3D FS-T2WIとT2FFEイメージングの併用により、3D FS-T2WIとDWIおよびADC併用と同等の正確度が得られ、肝血管腫と転移性腫瘍の鑑別に有用であることが確認された。

  • Association between Sarcopenia and Omega-3 Polyunsaturated Fatty Acid in Patients with Hepatocellular Carcinoma

    Itoh Shinji, Nagao Yoshihiro, Morita Kazutoyo, Kurihara Takeshi, Tomino Takahiro, Kosai-Fujimoto Yukiko, Harada Noboru, Fujita Nobuhiro, Ushijima Yasuhiro, Mori Masaki, Yoshizumi Tomoharu

    JMA Journal   5 ( 2 )   169 - 176   2022.4   ISSN:2433328X eISSN:24333298

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    <p><b>Introduction:</b> This study aimed to validate whether preoperative sarcopenia can predict long-term outcomes in patients with hepatocellular carcinoma (HCC) and identify the associations between sarcopenia and polyunsaturated fatty acids (PUFAs).</p><p><b>Methods:</b> This large, retrospective study included 353 patients who underwent hepatic resection for HCC and preoperative computed tomography scans. Skeletal muscle mass was measured at the third lumbar vertebrae. The cutoff value for sarcopenia followed the Japan Society of Hepatology's assessment criteria for sarcopenia.</p><p><b>Results:</b> Ninety-three patients (26.3%) with preoperative sarcopenia were enrolled. These patients had a significantly lower body mass index (p < 0.0001) and serum albumin level (p = 0.0070) as well as a higher rate of advanced-stage cancer (p = 0.0062) than those without sarcopenia. Patients with sarcopenia had significantly shorter overall survival than the other patients before (p = 0.0001) and after (p = 0.0415) propensity score matching. The sarcopenia group was significantly associated with low levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which were categorized based on omega-3 PUFAs, compared with those in the non-sarcopenia group (p = 0.0030 and p = 0.0135).</p><p><b>Conclusions:</b> We demonstrated an association between sarcopenia and the long-term prognosis in patients with HCC. Low EPA and DHA levels were associated with preoperative sarcopenia. Further prospective studies are needed to investigate whether nutritional support using omega-3 PUFAs can prevent and manage skeletal muscle mass depletion.</p>

    DOI: 10.31662/jmaj.2022-0037

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    CiNii Research

  • Association between Sarcopenia and Omega-3 Polyunsaturated Fatty Acid in Patients with Hepatocellular Carcinoma. Reviewed International journal

    Itoh S, Nagao Y, Morita K, Kurihara T, Tomino T, Kosai-Fujimoto Y, Harada N, Fujita N, Ushijima Y, Mori M, Yoshizumi T.

    JMA J.   5 ( 2 )   169 - 176   2022.4

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    DOI: 10.31662/jmaj.2022-0037.

  • 肝細胞癌患者におけるサルコペニアとオメガ-3多価不飽和脂肪酸との関連(Association between Sarcopenia and Omega-3 Polyunsaturated Fatty Acid in Patients with Hepatocellular Carcinoma)

    Itoh Shinji, Nagao Yoshihiro, Morita Kazutoyo, Kurihara Takeshi, Tomino Takahiro, Kosai-Fujimoto Yukiko, Harada Noboru, Fujita Nobuhiro, Ushijima Yasuhiro, Mori Masaki, Yoshizumi Tomoharu

    JMA Journal   5 ( 2 )   169 - 176   2022.4   ISSN:2433-328X

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    肝細胞癌患者において肝切除前のサルコペニアから術後の長期転帰を予測できるか検討し、サルコペニアと多価不飽和脂肪酸[エイコサペンタエン酸(EPA)およびドコサヘキサエン酸(DHA)]との関連を評価した。術前のCT画像から第3腰椎の骨格筋量を評価した。サルコペニアのカットオフ値は、日本肝臓学会のサルコペニア判定基準に従った。術前の血液検査でEPAとDHAを測定した。患者353例を解析対象とした。術前にサルコペニアを認めた患者(S群)は93例(中央値74歳、うち男性56例)。認めなかった患者(非S群)は260例(中央値70歳、男性191例)であった。S群は非S群よりBMI(p<0.0001)と血清アルブミン値(p=0.0070)が有意に低く、進行癌の割合が高かった(p=0.0062)。S群の全生存期間は非S群より有意に短かった(傾向スコアマッチング前p=0.0001、マッチング後p=0.0415)。S群は非S群よりEPAおよびDHAの低さと有意に関連した(p=0.0030およびp=0.0135)。以上から、肝細胞癌患者においてサルコペニアと長期予後は関連し、サルコペニアとEPAおよびDHAの低さも関連した。

  • Improvement of the Visibility of Hepatocellular Carcinoma Lesions in Early Phase Abdominal Contrast Enhanced Computed Tomography Images: Utilization of Optimal Pseudo-Colorization

    AKAMINE Hiroshi, MORISHITA Junji, KURAMOTO Taku, HAMASAKI Hiroshi, TAKARABE Shinya, WADA Noriaki, ISHIMATSU Keisuke, USHIJIMA Yasuhiro, KATO Toyoyuki, ISHIGAMI Kousei, SASAKI Masayuki

    福岡醫學雜誌   113 ( 1 )   7 - 17   2022.3   ISSN:0016254X

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    Purpose : The specific objectives of our study were to examine whether the visibility of hepatocellular carcinoma (HCC) lesions on early phase abdominal contrast-enhanced computed tomography (CT) images can be improved by optimal pseudo-colorization with a rainbow color map. / Methods : The chromaticity of grayscale and rainbow color maps displayed on a medical liquid-crystal display was measured using a colorimeter. The differences in the chromaticity, bE00, between the HCC lesion and liver parenchyma in 22 cases were evaluated. The rainbow color map was revised by changing only the window level (WL) to match the HCC lesion with a peak of bE00. Visual evaluation of the 22 cases was performed using Scheffeʼs paired comparison by ten observers. The average psychological measurement (a) was calculated using the grayscale, rainbow color map, and revised rainbow color map to examine the effectiveness of the proposed method. / Results : In all cases, the a measure was highest in the order of revised rainbow, grayscale, and rainbow. These results indicate that the visibility of HCC lesions in early phase abdominal contrastenhanced CT images could be improved by modifying the pseudo-color map with optimal colorization based on bE00. / Conclusions : The visibility of HCC lesions in early phase abdominal contrast-enhanced CT images was improved by shifting only the WL setting so that the HCC contrast would match the pixel range with higher bE00 on the rainbow color map. This method can be applied to various cases and color maps, and the visibility of the target lesion can be easily improved.

    DOI: 10.15017/4795999

    CiNii Research

  • 腹部造影CT動脈相における肝細胞癌病変の視認性の向上 最適な疑似カラー画像化の利用(Improvement of the Visibility of Hepatocellular Carcinoma Lesions in Early Phase Abdominal Contrast Enhanced Computed Tomography Images: Utilization of Optimal Pseudo-Colorization)

    赤嶺 寛地, 杜下 淳次, 倉本 卓, 濱崎 洋志, 寳部 真也, 和田 憲明, 石松 慶祐, 牛島 泰宏, 加藤 豊幸, 石神 康生, 佐々木 雅之

    福岡医学雑誌   113 ( 1 )   7 - 17   2022.3   ISSN:0016-254X

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    【目的】本研究は、腹部造影コンピュータ断層撮影(CT)動脈相における肝細胞癌(HCC)病変の視認性が、rainbowカラーマップを使用した適切な疑似カラー画像化によって改善することを目的とした。【方法】医用画像表示用液晶ディスプレイに表示されるgrayscaleおよびrainbowカラーマップの色度を、色彩輝度計を使用して測定した。2017年4月から2019年12月までに腹部造影CT動脈相を撮影された22症例のHCC病変を対象とした。22症例において、HCC病変と肝実質の間の色度の違い(ΔE00)を評価した。適切なカラー画像化として、ウィンドウレベル(WL)のみを変更して、HCC病変のコントラストがRainbowカラーマップのΔE00の最も高いピクセル範囲に一致するようにRainbowカラーマップを修正した(revised rainbow)。10名の観察者によりScheffeの一対比較法を用いて22症例のHCC病変の視認性を評価した。提案した手法の有用性を調査するため、grayscale、rainbow、revised rainbowそれぞれにおいて、平均嗜好度(α)を求めた。【結果】すべての症例において(α)は、revised rainbow、grayscale、rainbowの順に高かった。これらの結果は、提案手法であるΔE00に基づいた適切な疑似カラー画像化によって、腹部造影CT動脈相におけるHCC病変の視認性を改善できることを示している。【結論】腹部造影CT動脈相におけるHCC病変の視認性は、HCC病変のコントラストがrainbowカラーマップ上のより高いΔE00のピクセル範囲と一致するようにWL設定のみをシフトすることによって改善された。本提案手法は、さまざまな症例やカラーマップに適用でき、標的病変の視認性を簡単に向上させることができる。(著者抄録)

  • 腎細胞癌に対する凍結療法後3年の経過で発見された腎仮性動脈瘤の1例

    植山 達也, 牛島 泰宏, 浅山 良樹, 西江 昭弘, 中山 智博, 高山 幸久, 久保 雄一郎, 石松 慶祐, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌   36 ( 2 )   147 - 151   2022.3   ISSN:1340-4520

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    症例は40歳代男性。アルコール性肝硬変、陳旧性脳出血、糖尿病で加療中にCTで左腎細胞癌を指摘された。病変の大部分が腎実質に埋没しており、部分切除は困難と判断された。凍結療法目的で著者らの施設に紹介受診となった。造影CTで左腎上極腹側に1.8cm大の造影効果を伴う結節を認め、凍結針計3本を穿刺(1本は腎門部経由)して10分凍結、5分自然解凍、10分凍結を施行した。治療後3年の造影CTで凍結療法部に接して7mm大の造影効果を伴う結節が出現し、局所再発と考えた。また、凍結療法部から離れた左腎上極腎門部に10mm大の動脈瘤を疑う所見を認めた。再発腎細胞癌のリピオドールマーキングと仮性動脈瘤の塞栓を行い、翌日に再発腎細胞癌に対する凍結療法を行った。その後2年が経過したが、再発を認めていない。

  • Evaluation of safety and effectiveness of cryoablation in the treatment of renal angiomyolipoma related to tuberous sclerosis complex: The Cryo-TSC study.

    Kashiwagi, E; Asayama, Y; Hatano, T; Miki, J; Egawa, S; Takamoto, A; Nasu, Y; Osawa, T; Shinohara, N; Hongo, F; Ukimura, O; Nishie, A; Ushijima, Y; Kiyomi, F; Nakano, S; Arai, Y; Eto, M

    JOURNAL OF CLINICAL ONCOLOGY   40 ( 6 )   2022.2   ISSN:0732-183X eISSN:1527-7755

  • Diagnostic potential of T1ρ and T2 relaxations in assessing the severity of liver fibrosis and necro-inflammation. Invited Reviewed International journal

    Takayama Y, Nishie A, Ishimatsu K, Ushijima Y, Fujita N, Kubo Y, Yoshizumi T, Kouhashi KI, Maehara J, Akamine Y, Ishigami K.

    Magn Reson Imaging.   87   104 - 112   2022.1   ISSN:0730-725X eISSN:1873-5894

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    Purpose: To investigate the utility of T1ρ and T2 relaxations for assessing the severity of liver fibrosis (F stage) and necro-inflammation (A stage) in patients with chronic liver disease (CLD). Materials and methods: We calculated T1ρ and T2 relaxations of the liver parenchyma in 82 patients who underwent liver surgery. F and A stages of enrolled patients were assessed by referring to surgically resected specimens. The relationships between T1ρ or T2 relaxation and F or A stage were assessed using one-way analysis of variance followed by Tukey's multiple comparison test, Spearman's rank correlation test and a receiver operating characteristic analysis. Results: The T1ρ and T2 values of the liver parenchyma were significantly increased as the F and A stages progressed. The T1ρ and T2 values showed significant differences between F0 and F4, between F1 and F4, and between F2 and F4. In addition, T1ρ values showed a significant difference between F0 and F3 as well. The highest diagnostic ability for fibrosis was obtained when differentiating ≥F3 from ≤F2 using T1ρ: the sensitivity was 82.8%, the specificity 79.2% and the area under the curve (AUC) 0.87. The sensitivity and AUC of T1ρ relaxation (46.9% and 0.67) were significantly higher than those of T2 relaxation (29.7% and 0.60) for differentiating ≥A1 from A0. Conclusion: T1ρ and T2 relaxations have potential as a biochemical marker for assessing the severity of liver fibrosis and necro-inflammation. T1ρ relaxation may be slightly superior to T2 relaxation in terms of diagnostic ability for liver fibrosis and necro-inflammation.

    DOI: 10.1016/j.mri.2022.01.002

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  • Differentiating Liver Hemangioma from Metastatic Tumor Using T2-enhanced Spin-echo Imaging with a Time-reversed Gradient-echo Sequence in the Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging

    Takayama Yukihisa, Nishie Akihiro, Okamoto Daisuke, Fujita Nobuhiro, Asayama Yoshiki, Ushijima Yasuhiro, Yoshizumi Tomoharu, Yoneyama Masami, Ishigami Kousei

    Magnetic Resonance in Medical Sciences   21 ( 3 )   445 - 457   2022   ISSN:13473182 eISSN:18802206

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    <p>Purpose: To evaluate the utility of T2-enhanced spin-echo imaging using the time-reversed gradient echo sequence (T2FFE imaging) in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI (Gd-EOB-MRI) for differentiating hemangiomas from metastatic tumors.</p><p>Methods: A total of 61 patients with 133 liver lesions, including 37 hemangiomas and 96 metastatic tumors, were scanned by Gd-EOB-MRI. Four data sets were independently analyzed by two readers: (1) 3D fat-suppressed T2-weighted imaging (FS-T2WI) alone; (2) the combination of 3D FS-T2WI and T2FFE imaging in the HBP of Gd-EOB-MRI; (3) the combination of 3D FS-T2WI, diffusion-weighted imaging (DWI) with the b-value of 1000 s/mm<sup>2</sup> and the apparent diffusion coefficient (ADC); and (4) a dynamic study of Gd-EOB-MRI. After classifying the lesion sizes as ≤ 10 mm or > 10 mm, we conducted a receiver-operating characteristic analysis to compare diagnostic accuracies among the four data sets for differentiating hemangiomas from metastatic tumors.</p><p>Results: The areas under the curves (AUCs) of the four data sets of two readers were: (1) ≤ 10 mm (0.85 and 0.91) and > 10 mm (0.88 and 0.97), (2) ≤ 10 mm (0.94 and 0.94) and > 10 mm (0.96 and 0.95), (3) ≤ 10 mm (0.90 and 0.87) and > 10 mm (0.89 and 0.95), and (4) ≤ 10 mm (0.62 and 0.67) and > 10 mm (0.76 and 0.71), respectively. Data sets (2) and (3) showed no significant differences in AUCs, but both showed significantly higher AUCs compared to that of (4) regardless of the lesion size (<i>P</i> < 0.05).</p><p>Conclusion: The combination of 3D FS-T2WI and T2FFE imaging in the HBP of Gd-EOB-MRI achieved an accuracy equivalent to that of the combination of 3D FS-T2WI, DWI, and ADC and might be helpful in differentiating hemangiomas from metastatic tumors.</p>

    DOI: 10.2463/mrms.mp.2020-0151

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  • The Role of Biopsy and Clinical Imaging in the Management of Soft Tissue Tumor

    Sagiyama Koji, Kamitani Takeshi, Yamasaki Yuzo, Hida Tomoyuki, Matsuura Yuko, Yabuuchi Hidetake, Ushijima Yasuhiro, Ishigami Kousei

    The Official Journal of the Japanese Society of Interventional Radiology   36 ( 2 )   119 - 125   2022   ISSN:13404520 eISSN:21856451

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    The clinical diagnosis of soft tissue tumors, especially malignant sarcomas, is highly dependent on histopathological diagnosis by biopsy. However, the rarity of sarcomas makes it difficult to accumulate knowledge and improve techniques, and inappropriate biopsies are frequently performed. Inappropriate biopsy techniques can make surgery difficult and worsen the patient's prognosis, and so biopsies should be performed by experienced operators in appropriate facilities. The important thing to note during biopsy is that the tumor capsule is disrupted at biopsy, and the access route is invariably “contaminated” with tumor. Therefore, the technique and route of biopsy must consider that the access route must be removed along with the tumor during wide resection after biopsy. In addition, the target should be carefully defined to avoid necrosis and hemorrhage and to biopsy the components with high viability. Accordingly, it is important to examine the surrounding anatomy and internal structure of the tumor in detail preoperatively using appropriate imaging modalities in order to perform an effective and safe biopsy.

    DOI: 10.11407/ivr.36.119

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  • Renal Pseudoaneurysm Detected 3 Years after Cryoablation for Renal Cell Carcinoma

    Ueyama Tatsuya, Ushijima Yasuhiro, Asayama Yoshiki, Nishie Akihiro, Nakayama Tomohiro, Takayama Yukihisa, Kubo Yuichiro, Ishimatsu Keisuke, Ishigami Kousei

    The Official Journal of the Japanese Society of Interventional Radiology   36 ( 2 )   147 - 151   2022   ISSN:13404520 eISSN:21856451

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    We treated a patient with a pseudoaneurysm detected 3 years after cryoablation for renal cell carcinoma (RCC). The pseudoaneurysm was located in the hilar region of the kidney, which was the puncture route of the cryo-needle but outside the area of the cryoablation. The puncture through the renal hilum was thought to be one of the factors that led to the development of the pseudoaneurysm. Since the angiographic findings revealed the pseudoaneurysm to be accompanied by an arteriovenous fistula, we speculate that the arteriovenous fistula was first induced by the renal hilar puncture and that the pseudoaneurysm was formed by prolonged arterial pressure stimulation. The development of arteriovenous fistulae and pseudoaneurysms should be considered in cases in which cryoablation for RCC is performed by a puncture through the renal hilum.

    DOI: 10.11407/ivr.36.147

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  • Hemodynamic Alteration in the Liver in Acute Hepatitis: A Quantitative Evaluation Using Computed Tomographic Perfusion. Reviewed International journal

    Nishie A, Ushijima Y, Takayama Y, Fujita N, Kubo Y, Ishimatsu K, Tsurumaru D, Kohjima M, Ishigami K.

    In Vivo   2021.11

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    DOI: 10.21873/invivo.12656.

  • Radiology- and gene-based risk stratification in small renal cell carcinoma: A preliminary study. Reviewed International journal

    Takao S, Ushijima Y, Motomura Y, Sakamoto K, Hirakawa M, Nishie A, Mimori K, Yamashita Y, Tsutsumi T, Ishigami K.

    PLoS One   2021.9

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    目的:小径腎癌は一般的に予後良好であるが、高悪性度の一部は転移し予後不良となり、予後不良群を抽出するリスク層別化因子の同定が望まれている。本研究では、ゲノムプロファイリングとperfusion CT (pCT)やMRIの所見との関係性を評価し、有効なバイオマーカーとして利用できるイメージング因子の同定を試みた。
    方法:2018/4~2019/3の間にpCT、MRIを施行した淡明細胞癌18例に対して生検組織からRNA sequenceを施行し発現量を求めた。本研究では腎癌におけるゲノムプロファィリングを元とした予後因子に細胞周期(CCP)スコアとclear cell type A/ clear cell type B (ccA/ccB) サブタイプを採用した。CCPスコアは腎癌における転移の独立予後因子、ccA/ccBサブタイプではccAに分類された症例はccBに対して予後が良好なことが判明している。
    腫瘍の画像評価では、腫瘍径と脂肪・偽被膜の有無を評価し、また腫瘍の画像パラメータ(Ktrans・Kep・VE・VP・ADC)を測定した。これらのパラメータと腫瘍径腫瘍のザイズ、RNA発現との関連性を評価した。
    結果:腫瘍径はKepと正の相関、VE, VP, ADC, 血管新生のRNA発現と負の相関を示した。CCPスコアはKep. KtransKtrans, Kepと負の相関を示した。ccAに分類された腫瘍ではMRIで偽被膜が観察しやすい傾向があった。
    結論:腫瘍径は腫瘍の低灌流と関連があったが、ゲノムプロファイリングをもとにした予後因子との関連は見られなかった。KtransやKepといったパラメータや偽被膜といった腫瘍の特徴は遺伝子ベースのリスク層別化を可能にするかもしれない。

    DOI: 10.1371/journal.pone.0256471

  • Improvement of Image Quality Using Hybrid Iterative Reconstruction with Noise Power Spectrum Model in Computed Tomography During Hepatic Arteriography. Reviewed International journal

    Hamasaki H, Shirasaka T, Ushijima Y, Akamine H, Takayama Y, Kubo Y, Ishimatsu K, Nishie A, Kato T.

    J Belg Soc Radiol.   105 ( 1 )   2021.9

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    DOI: 10.5334/jbsr.2444.

  • Image quality improvement with deep learning-based reconstruction on abdominal ultrahigh-resolution CT: A phantom study. Reviewed International journal

    Shirasaka T, Kojima T, Funama Y, Sakai Y, Kondo M, Mikayama R, Hamasaki H, Kato T, Ushijima Y, Asayama Y, Nishie A.

    J Appl Clin Med Phys.   22 ( 7 )   286 - 296   2021.7

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    DOI: 10.1002/acm2.13318.

  • Congestion Area of the Right Lobe Graft in Living Donor Liver Transplantation: Quantitative Evaluation of Hemodynamics Using Computed Tomography Perfusion. Reviewed International journal

    Morita K, Nishie A, Asayama Y, Ushijima Y, Takayama Y, Okamoto D, Fujita N, Ikegami T, Yoshizumi T, Ishigami K.

    Transplant Proc.   53 ( 5 )   1653 - 1658   2021.6

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    DOI: 10.1016/j.transproceed.2021.02.024.

  • Noninvasive assessment of liver fibrosis by dual-layer spectral detector CT. Reviewed International journal

    Morita K, Nishie A, Ushijima Y, Takayama Y, Fujita N, Kubo Y, Ishimatsu K, Yoshizumi T, Maehara J, Ishigami K.

    Eur J Radiol. 2021   136   10975   2021.3

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    DOI: 10.1016/j.ejrad.2021.109575.

  • Cryoablation for Secondary Renal Cell Carcinoma After Surgical Nephrectomy Reviewed International journal

    Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Yukihisa Takayama, Yuichiro Kubo, Keisuke Ishimatsu, Kousei Ishigami

    Cardiovascular and Interventional Radiology   44(3)   414 - 420   2021.3

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    DOI: 10.1007/s00270-020-02709-w

  • Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent. Reviewed International journal

    Fujita N, Nishie A, Asayama Y, Ishigami K, Nakayama T, Ushijima Y, Kakihara D, Takayama Y, Morita K, Ishimatsu K, Takao S, Yoshizumi T, Furusyo N, Honda H.

    Magn Reson Med Sci.   19 ( 4 )   389 - 393   2020.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2463/mrms.tn.2019-0183.

  • Quantitative evaluation of liver function and pathology with hepatocyte fraction on Gadoxetic acid-enhanced MR imaging. Reviewed International journal

    Fujita N, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Takayama Y, Yoshizumi T, Hida T, Oda Y, Okuaki T, Honda H.

    Magn Reson Imaging.   73 ( 125 )   129   2020.10

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    DOI: 10.1016/j.mri.2020.08.018.

  • Improved visualization of a fine intrahepatic biliary duct on drip infusion cholangiography-computed tomography: Impact of knowledge-based iterative model reconstruction. Reviewed International journal

    Takao S, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Nakayama T, Fujita N, Morita K, Ishimatsu K, Yoshizumi T, Ikegami T, Kondo M, Honda H.

    Hepatol Res.   50 ( 5 )   629 - 634   2020.5

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    DOI: 10.1111/hepr.13477.

  • Safety and Efficacy of Embolization Using N-Butyl Cyanoacrylate via a Percutaneous Direct Approach for Endoleaks after Abdominal/Thoracic Endovascular Aortic Repair Reviewed International journal

    Ushijima Y, Asayama Y, Nishie A, Ishigami K, Takayama Y, Okamoto D, Fujita N, Morita K, Honda H.

    Interventional Radiology   2020.3

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  • Hyperintense Liver Masses at Hepatobiliary Phase Gadoxetic Acid-enhanced MRI: Imaging Appearances and Clinical Importance Reviewed International journal

    Fujita N, Nishie A, Asayama Y, Ishigami K, Ushijima Y, Kakihara D, Nakayama T, Morita K, Ishimatsu K, Honda H.

    Radiographics.   40 ( 1 )   72 - 94   2020.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1148/rg.2020190037.

  • Amide proton transfer imaging for differentiating benign ovarian cystic lesions: Potential of first time right. Reviewed International journal

    Ishimatsu K, Nishie A, Takayama Y, Asayama Y, Ushijima Y, Kakihara D, Morita K, Takao S, Sonoda K, Ohishi Y, Honda H.

    Eur J Radiol.   120   108656   2019.11

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    DOI: 10.1016/j.ejrad.2019.108656.

  • Superparamagnetic iron-oxide-enhanced diffusion-weighted magnetic resonance imaging for the diagnosis of intrapancreatic accessory spleen. Reviewed International journal

    Ishigami K, Nishie A, Nakayama T, Asayama Y, Kakihara D, Fujita N, Ushijima Y, Okamoto D, Ohtsuka T, Mori Y, Ito T, Mochidome N, Honda H.

    Abdom Radiol (NY).   44 ( 10 )   3325 - 3335   2019.10

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    DOI: 10.1007/s00261-019-02189-8.

  • Usefulness of a Pretreatment CT-Based Modified RENAL Nephrometry Score in Predicting Renal Function After Cryotherapy for T1a Renal Mass. Reviewed International journal

    Asayama Y, Nishie A, Ushijima Y, Okamoto D, Morita K, Takao S, Kakihara D, Ishimatsu K, Ishigami K, Fujita N, Honda H.

    Cardiovasc Intervent Radiol.   42 ( 8 )   1128 - 1134   2019.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00270-019-02238-1.

  • Imaging features of undifferentiated carcinoma of the pancreas. Reviewed International journal

    Ishigami K, Nishie A, Yamamoto T, Asayama Y, Ushijima Y, Kakihara D, Fujita N, Morita K, Ohtsuka T, Kawabe K, Mochidome N, Honda H.

    J Med Imaging Radiat Oncol.   63 ( 5 )   580 - 588   2019.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1754-9485.12925

  • Prognostic Factors of Computed Tomography Findings in Patients with Severe Acute Hepatic Failure Scheduled to Undergo Transcatheter Arterial Steroid Injection Therapy Reviewed International journal

    Ushijima Y, Asayama Y, Nishie A, Tajima T, Yoshimitsu K, Hirakawa M, Ishigami K, Kakihara D, Okamoto D, Kotoh K, Honda H

    Interventional Radiology   2019.3

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  • A Retroperitoneal Isolated Enteric Duplication Cyst Mimicking a Teratoma: A Case Report and Literature Review. Reviewed International journal

    Daichi Momosaka, Yasuhiro Ushijima, Akihiro Nishie, Asayama Yoshiki, Ishigami Kousei, Takayama yukihisa, Daisuke Okamoto, Nobuhiro Fujita, Hiroshi Honda

    Case Report in Radiology   2016.12

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  • Detecting hepatic nodules and identifying feeding arteries of hepatocellular carcinoma: efficacy of cone-beam computed tomography in transcatheter arterial chemoembolization Reviewed International journal

    Ushijima Y, Tajima T, Nishie A, Asayama Y, Ishigami K, Hirakawa M, Kakihara D, Okamoto D, Honda H.

    Hepatoma Res   2016.1

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  • Radiological catheter placement for transcatheter arterial steroid injection therapy to treat severe acute hepatic failure: technical feasibility and efficacy. Reviewed International journal

    Ushijima Y, Tajima T, Yoshimitsu K, Irie H, Nishie A, Hirakawa M, Ishigami K, Okamoto D, Kotoh K, Honda H

    Acta Radiologica   2012.3

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  • Quantitative analysis of liver function using superparamagnetic iron oxide- and Gd-EOB-DTPA-enhanced MRI: Comparison with Technetium-99m galactosyl serum albumin scintigraphy. International journal

    Nishie A, Ushijima Y, Tajima T, Asayama Y, Ishigami K, Kakihara D, Nakayama T, Takayama Y, Okamoto D, Abe K, Obara M, Yoshimitsu K, Honda H.

    Eur J Radiol.   2011.5

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  • MRI findings of pancreatic lymphoma and autoimmune pancreatitis: a comparative study. International journal

    Ishigami K, Tajima T, Nishie A, Ushijima Y, Fujita N, Asayama Y, Kakihara D, Irie H, Ito T, Igarashi H, Nakamura M, Honda H.

    Eur J Radiol.   2010.6

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  • Detection of hepatocellular carcinoma (HCC) using super paramagnetic iron oxide (SPIO)-enhanced MRI: Added value of diffusion-weighted imaging (DWI). International journal

    Nishie A, Tajima T, Ishigami K, Ushijima Y, Okamoto D, Hirakawa M, Nishihara Y, Taketomi A, Hatakenaka M, Irie H, Yoshimitsu K, Honda H.

    J Magn Reson Imaging.   2010.2

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  • Recanalization of splenic artery aneurysm after transcatheter arterial embolization using N-butyl cyanoacrylate. International journal

    Matsumoto K, Ushijima Y, Tajima T, Nishie A, Hirakawa M, Ishigami K, Yamaji Y, Honda H.

    Cardiovasc Intervent Radiol.   2010.2

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  • Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis. International journal

    Yanaru-Fujisawa R, Matsumoto T, Ushijima Y, Esaki M, Hirahashi M, Gushima M, Yao T, Nakabeppu Y, Iida M.

    Clin Genet.   2008.6

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  • A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA. International journal

    Ushijima Y, Tominaga Y, Miura T, Tsuchimoto D, Sakumi K, Nakabeppu Y.

    Nucleic Acids Res.   33 ( 2 )   672 - 682   2005.1

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    DOI: 10.1093/nar/gki214

  • MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. International journal

    Tominaga Y, Ushijima Y, Tsuchimoto D, Mishima M, Shirakawa M, Hirano S, Sakumi K, Nakabeppu Y.

    Nucleic Acids Res.   32 ( 10 )   3198 - 3211   2004.6

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    DOI: 10.1093/nar/gkh642

  • Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts. International journal

    Ichinoe A, Behmanesh M, Tominaga Y, Ushijima Y, Hirano S, Sakai Y, Tsuchimoto D, Sakumi K, Wake N, Nakabeppu Y.

    Nucleic Acids Res   32 ( 2 )   477 - 487   2004.1

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    DOI: 10.1093/nar/gkh214

  • Mutator phenotype of MUTYH-null mouse embryonic stem cells.

    Hirano S, Tominaga Y, Ichinoe A, Ushijima Y, Tsuchimoto D, Sakumi K, Nakabeppu Y.

    J Biol Chem   278 ( 40 )   38121 - 38124   2003.10

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    DOI: 10.1074/jbc.C300316200

  • 直腸癌術後経過中に発症した肺類上皮血管内皮腫の1例

    牛島泰宏、村田繁利、真武邦茂、角南俊哉、澤本博文

    臨床放射線   2000.1

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Books

  • 即戦力が身につく肝胆膵の画像診断「膵十二指腸動脈瘤」「術後合併症」

    牛島泰宏(Role:Joint author)

    メデイカル・サイエンス・インターナショナル  2023.4 

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    Language:Japanese   Book type:Scholarly book

  • 肝胆膵のCT・MRI 「肝腺腫」「Multicystic biliary hamartoma」[成人型肝細胞癌]

    牛島 泰宏(Role:Joint author)

    メディカル・サイエンス・インターナショナル  2016.4 

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    Language:Japanese   Book type:Scholarly book

Presentations

  • CT-guided cryoablation for renal cell carcinoma: pitfalls, and tips to ensure accuracy and safety International conference

    Yasuhiro Ushijima, Daisuke Okamoto, Nobuhiro Fujita, Keisuke Ishimatsu, Kousuke Tabata, Satoshi Makise and Kousei Ishigami

    105th Scientific Assembly and Annual Meeting of Radiological Society of North America  2024.12 

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    Event date: 2024.12

    Language:English  

    Country:United States  

    腎細胞癌に対するCTガイド下凍結療法についてまとめた教育展示

  • 腎癌の凍結療法

    牛島泰宏

    日本泌尿器腫瘍学会第10回学術集会  2024.10 

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    Event date: 2024.10

  • Cryoablation for renal cell carcinoma in patients with Von-Hippel-Lindau disease: A retrospective analysis of tumor control and renal function

    Yasuhiro Ushijima, Daisuke Okamoto, Nobuhiro Fujita, Keisuke Ishimatsu, Masahiro Itoyama, Kousuke Tabata, Kousei Ishigami

    第83回日本医学放射線学会総会  2024.4 

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    Event date: 2024.4

  • A follow-up study of late-stage elderly patients treated with cryoablation for small-sized renal cell carcinoma

    牛島泰宏、岡本大佑、藤田展宏、石松慶祐、村山 僚、糸山昌宏、石神康生

    第52回日本IVR学会総会、  2023.5 

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    Event date: 2023.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:高知   Country:Japan  

  • Impact of lipiodol marking before CT-guided cryoablation on the outcome of sporadic renal cell carcinoma

    Yasuhiro Ushijima, Nobuhiro Fujita, Keisuke Ishimatsu, Noriaki Wada, Seiichiro Takao and Kousei Ishigami

    第51回日本IVR学会総会、  2022.6 

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    Event date: 2022.6 - 2023.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神戸   Country:Japan  

  • Type II endoleak after abdominal/thoracic endovascular repair (EVAR/TEVAR); How to diagnose and treat it in patients with renal dysfunction International conference

    Yasuhiro Ushijima, Akihiro Nishie, Nobuhiro Fujita, Keisuke Ishimatsu, Noriaki Wada, Seiichiro Takao, and Kousei Ishigami

    102nd Scientific Assembly and Annual Meeting of Radiological Society of North America  2021.12 

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    Event date: 2022.5

    Language:English  

    Country:United States  

  • 小径腎細胞癌に対する凍結療法における経皮的生検の診断能についての検討

    Yasuhiro Ushijima, Akihiro Nishie, Yukihisa Takayama, Nobuhiro Fujita, Yuichiro Kubo, Keisuke Ishimatsu, and Kousei Ishigami

    第50回日本IVR学会総会  2021.5 

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    Event date: 2021.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 腎摘出術後の二次的治療として行う腎細胞癌に対する凍結療法の有用性についての検討

    牛島泰宏、浅山良樹、西江明弘、中山智博、高山幸久、久保雄一郎、石松慶祐、石神康生

    第49回日本IVR学会総会  2020.8 

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    Event date: 2020.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Efficacy of transarterial lipiodol-marking before CT-guided cryoablation for renal cell carcinoma International conference

    Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Daisuke Kakihara, Yukihisa Takyama, Kouichiro Morita, Keisuke Ishimatsu, Seiichiro Takao and Hiroshi Honda

    CIRSE 2019  2019.9 

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    Event date: 2019.9

    Language:English  

    Country:Spain  

  • 腎細胞癌に対するCTガイド下凍結療法前に施行するリピオドールマーキングの有用性についての検討

    牛島 泰宏, 浅山 良樹, 西江 昭弘,柿原 大輔, 高山 幸久, 森田 孝一郎, 石松 慶祐、高尾 誠一朗、本田 浩

    第48会日本IVR学会  2019.5 

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    Event date: 2019.5 - 2019.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Safety and clinical contribution of CT-guided biopsy for cervical vertebral lesion International conference

    Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Kousei Ishigami, Daisuke Kakihara, Nobuhiro Fujita, Koichiro Morita, Keisuke Ishimatsu, Seiichiro Takao and Hiroshi Honda

    25th European Congress of Radiology 2019  2019.2 

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    Event date: 2019.2 - 2018.3

    Language:English  

    Venue:Varna   Country:Austria  

  • Safety and clinical contribution of CT-guided biopsy for cervical vertebral lesion International conference

    Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Kousei Ishigami, Daisuke Kakihara, Nobuhiro Fujita, Koichiro Morita, Keisuke Ishimatsu, Seiichiro Takao and Hiroshi Honda

    The 47th Annual Meeting of the Japanese Society of Interventional Radiology, The 13th International Symposium on Interventional Radiology (ISIR)  2018.5 

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    Event date: 2018.5 - 2018.6

    Language:English  

    Country:Japan  

  • 大動脈ステント留置後のtypeIIエンドリークに対する、ドップラー・ソナゾイドUSの初期経験

    牛島 泰宏, 浅山 良樹, 西江 昭弘, 石神 康生, 高山 幸久, 岡本 大佑, 本田 浩

    第184回日本医学放射線学会九州地方会  2017.2 

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    Event date: 2017.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Embolization for re-canalized internal iliac aneurysm after EVAR or graft replacement International conference

    Yasuhiro Ushijima, Asayama Yoshiki, Kousei Ishigami, Yukihisa Takayama, Daisuke Okamoto, Nobuhiro Fujita, Matsumoto Takuya, Hiroshi Honda

    The 44th Annual Meeting of the Japanese Society of Interventional Radiology(JSIR), The 11th International Symposium on Interventional Radiology (ISIR)  2015.5 

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    Event date: 2016.5

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Miyazaki   Country:Japan  

  • TEVAR後のエンドリークに対する経皮的直接穿刺による塞栓術の検討

    牛島 泰宏, 浅山 良樹, 西江 昭弘, 石神 康生, 高山 幸久, 岡本 大佑, 藤田 展宏, 森田 孝一郎, 松本 拓也, 大石 恭久, 富永 隆治, 本田 浩

    放射線学会九州地方会  2015.2 

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    Event date: 2015.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

  • EVAR/TEVAR後のエンドリークに対する、経皮的直接穿刺によるNBCAを用いた塞栓術の安全性と有用性の検討

    牛島 泰宏, 浅山 良樹, 西江 昭弘, 高山 幸久, 岡本 大佑, 藤田 展宏, 森田 孝一郎, 松尾 芳雄, 松本 拓也, 大石 恭久, 富永 隆治, 本田 浩

    第43回日本IVR学会総会  2014.6 

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    Event date: 2014.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:奈良   Country:Japan  

  • Clinical efficacy of Gd-EOB-DTPA-enhanced MRI in transcatheter arterial chemoembolization for hepatocellular carcinoma International conference

    牛島 泰宏, 西江 昭弘, 浅山 良樹, 高山 幸久, 藤田 展宏, 本田 浩

    20th European Congress of Radiology  2014.3 

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    Event date: 2014.3

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Viena   Country:Austria  

  • X線透視で認識が難しい血管内異物の回収に成功した2例

    森田 孝一郎, 牛島 泰宏, 浅山 良樹, 西江 昭弘, 高山 幸久, 藤田 展宏, 中島 淳博, 富永 隆治, 向井 靖, 本田 浩

    九州IVR地方会  2013.12 

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    Event date: 2013.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

  • 腹部骨盤領域のN-butyl cyanoacrylate を用いた動脈塞栓術

    牛島 泰宏, 浅山 良樹, 高山 幸久, 藤田 展宏, 本田 浩

    第42回日本IVR学会総会  2013.5 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:軽井沢   Country:Japan  

  • 腎盂癌の検出におけるMRI拡散強調像の有用性

    牛島泰宏、西江昭弘、浅山良樹、石神康生、高山幸久、藤田展宏、柿原大輔 久保雄一郎 本田 浩

    第71回日本医学放射線学会総会  2013.4 

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    Event date: 2013.4

    Venue:横浜   Country:Japan  

  • 肝細胞癌に対するTACE/Lipi-TAIにおけるEOB-MRIの有用性

    牛島 泰宏, 西江 昭弘, 浅山 良樹, 高山 幸久, 藤田 展宏, 本田 浩

    第72回日本医学放射線学会総会  2013.4 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 尿管温存に成功した腎細胞癌に対するRFAの一例

    真鍋 祐介, 牛島 泰宏, 西江 昭弘, 浅山 良樹, 高山 幸久, 藤田 展宏, 内藤 誠二, 本田 浩

    九州IVR地方会  2012.12 

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    Event date: 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Peirbiliary arterial plexus; normal anatomy and clinical significance for hepato-biliary-pancreatic system International conference

    Yasuhiro Ushijima

    94rd Scientific Assembly and Annual Meeting of Radiological Society of North America  2012.11 

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    Event date: 2012.11

    Language:English  

    Country:United States  

  • Efficacy of diffusion-weighted magnetic resonance imaging in detection of renal pelvic cancer International conference

    Yasuhiro Ushijima, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Daisuke Kakihara, Yukihisa Takayama, Nobuhiro Fujita, Yuichiro Kubo, Seiji Naito, Hiroshi Honda

    Radiology Congress of North East Asia (RCNEA)  2012.9 

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    Event date: 2012.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Nagasaki   Country:Japan  

  • Peirbiliary arterial plexus; normal anatomy and clinical significance for hepato-biliary-pancreatic system International conference

    Yasuhiro Ushijima, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Daisuke Kakihara, Yukihisa Takayama, Nobuhiro Fujita, Kanehiro Hasuo, and Hiroshi Honda

    The 37th Annual Meeting of the Japanese Society of Interventional Radiology(JSIR), The 10th International Symposium on Interventional Radiology (ISIR)  2012.5 

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    Event date: 2012.5 - 2012.6

    Country:Japan  

  • Detecting hepatic nodules and feeding arteries of hepatocellular carcinoma: efficacy of cone-beam CT in transcatheter arterial chemoinfusion or embolization International conference

    Yasuhiro Ushijima, Tsuyoshi Tajima, Akihiro Nishie, Kousei Ishigami, Daisuke Kakihara, Hiroshi Honda, Daisuke Okamoto

    94rd Scientific Assembly and Annual Meeting of Radiological Society of North America  2008.11 

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    Event date: 2011.11 - 2011.12

    Venue:Chicago   Country:United States  

  • 医原性腹壁動脈損傷に対するTAEの有用性

    牛島泰宏、田嶋 強、西江昭弘、浅山良樹、石神康生、柿原大輔、松本俊一、本田 浩

    第38回日本IVR学会総会  2009.8 

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    Event date: 2011.8

    Venue:大阪   Country:Japan  

  • 重症急性肝障害に対するステロイド動注療法:肝動脈内カテーテル留置術に関する検討

    牛島泰宏、田嶋 強、吉満研吾、入江裕之、西江昭弘、平川雅和、石神康生、岡本大佑、本田 浩、古藤和浩

    第36回日本IVR学会総会  2011.5 

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    Event date: 2011.5

    Venue:金沢   Country:Japan  

  • 退形成性膵癌の2例

    牛島泰宏、蓮尾金博、志多由孝、待鳥詔洋、江上順子、古賀友三、山田 泉、村上佳菜子、前田浩喜、岡藤孝史、山崎誘三、安座間喜明、枝元良広、伊東干城

    第24回腹部放射線研究会  2010.6 

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    Event date: 2010.6

    Venue:軽井沢   Country:Japan  

  • Prognostic factors in patients with severe acute hepatic failure who will undergo transcatheter arterial steroid injection therapy International conference

    Yasuhiro Ushijima, Tsuyoshi Tajima, Akihiro Nishie, Kousei Ishigami, Daisuke Kakihara, Hiroshi Honda, Daisuke Okamoto, Kazuhiro Kotoh, Munechika Enjohji

    94rd Scientific Assembly and Annual Meeting of Radiological Society of North America  2008.11 

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    Event date: 2008.12 - 2008.11

    Venue:Chucago   Country:United States  

  • Prognostic factors in patients with severe acute hepatic failure who will undergo transcatheter arterial steroid injection therapy International conference

    Yasuhiro Ushijima, Tsuyoshi Tajima, Akihiro Nishie, Kousei Ishigami, Daisuke Kakihara, Hiroshi Honda, Daisuke Okamoto, Kazuhiro Kotoh, Munechika Enjohji

    The 37th Annual Meeting of the Japanese Society of Interventional Radiology(JSIR), The 10th International Symposium on Interventional Radiology (ISIR)  2008.5 

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    Event date: 2008.5

    Venue:Karuizawa   Country:Japan  

  • Cone-beam CTの肝細胞癌血管内治療における腫瘍・栄養血管の検出能および治療効果についての検討

    牛島泰宏、田嶋 強、吉満研吾、入江裕之、西江昭弘、平川雅和、石神康生、岡本大佑、本田 浩

    第67回日本医学放射線学会総会  2008.4 

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    Event date: 2008.4

    Venue:横浜   Country:Japan  

  • 過去の治療に起因するS4肝実質の萎縮・線維化が原因と思われた肝内吻合枝発達不良による肝動脈一本化の不成功例:肝動注リザーバー留置術における注意点

    牛島泰宏、吉満研吾、入江裕之、田嶋 強、西江昭弘、平川雅和、石神康生、岡本大佑、本田 浩

    第165回日本医学放射線学会九州地方会  2007.6 

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    Event date: 2007.6 - 2011.6

    Venue:熊本   Country:Japan  

  • 高度な線維化が見られ非典型的な画像所見を呈した膵臓のmalignant endocrine tumorの1例

    牛島泰宏、吉満研吾、入江裕之、田嶋 強、西江昭弘、平川雅和、石神康生、岡本大佑、本田 浩、山口幸二、西原雄之介

    第21回腹部放射線研究会  2007.6 

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    Event date: 2007.6

    Venue:宮崎   Country:Japan  

  • Linear Profile Ordering を用いた脂肪抑制3DT1強調像の膵実質評価における有用性

    牛島泰宏、吉満研吾、入江裕之、田嶋 強、浅山良樹、平川雅和、石神康生、本田 浩

    第34回日本磁気共鳴医学会大会  2006.9 

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    Event date: 2006.9

    Venue:筑波   Country:Japan  

  • 乳頭型の胆管癌の1例

    牛島泰宏、吉満研吾、入江裕之、田嶋 強、浅山良樹、平川雅和、石神康生、柿原大輔、本田 浩、山口幸二、西原 雄之介

    第20回腹部放射線研究会  2006.5 

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    Event date: 2006.5 - 2006.7

    Venue:東京   Country:Japan  

  • 高度腎機能障害症例における凍結療法の検討

    高尾 誠一朗, 牛島 泰宏, 西江 昭弘, 藤田 展宏, 石松 慶祐, 和田 憲明, 石神 康生

    Japanese Journal of Radiology  2023.2  (公社)日本医学放射線学会

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  • 進行胃癌術後再発予測における造影CTを用いたExtracellular volume fraction解析の有用性

    西牟田 雄祐, 鶴丸 大介, 藤田 展宏, 甲斐 聖広, 牛島 泰宏, 石神 康生, 沖 英次

    日本医学放射線学会秋季臨床大会抄録集  2022.8  (公社)日本医学放射線学会

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  • 腎細胞癌部分切除後の播種再発に対するCTガイド下凍結療法の有用性

    岡本 大佑, 牛島 泰宏, 藤田 展宏, 石松 慶祐, 糸山 昌宏, 田畑 公佑, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌  2024.4  (一社)日本インターベンショナルラジオロジー学会

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  • 腎細胞癌に対する凍結療法前に施行する左橈骨動脈穿刺でのリピオドールマーキングの実効性についての検討

    田畑 公佑, 牛島 泰宏, 岡本 大佑, 藤田 展宏, 石松 慶祐, 糸山 昌宏, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌  2024.4  (一社)日本インターベンショナルラジオロジー学会

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  • 胸部X線動態撮影で塞栓術前後の血流変化を評価した肺動静脈奇形の3例

    樋田 知之, 山崎 誘三, 松浦 由布子, 鷺山 幸二, 神谷 武志, 和田 憲明, 牛島 泰宏, 石神 康生, 藪内 英剛

    Japanese Journal of Radiology  2023.2  (公社)日本医学放射線学会

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  • 肝血管肉腫による腹腔内出血に対して術前IVR・左肝切除で救命した1例

    今村 柾紀, 井手野 昇, 伊東 守, 牛島 泰宏, 阿部 俊也, 池永 直樹, 仲田 興平, 中村 雅史

    日本腹部救急医学会雑誌  2022.2  (一社)日本腹部救急医学会

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  • 甲状腺癌に対する放射性ヨウ素内用療法において子宮筋腫に強いヨウ素集積を認めた1例

    井上 紗也香, 馬場 眞吾, 磯田 拓郎, 丸岡 保博, 北村 宜之, 牛島 泰宏, 石神 康生, 佐々木 雅之

    Japanese Journal of Radiology  2024.2  (公社)日本医学放射線学会

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  • 散発性RCCに対するCTガイド下凍結療法の前に施行するリピオドールマーキングが治療成績に与える影響(Effect of lipiodol marking before CT-guided cryoablation on the outcome of sporadic RCC)

    Ushijima Yasuhiro, Fujita Nobuhiro, Ishimatsu Keisuke, Wada Noriaki, Takao Seiichiro, Ishigami Kousei

    日本インターベンショナルラジオロジー学会雑誌  2022.5  (一社)日本インターベンショナルラジオロジー学会

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  • 後腹膜腫瘍および体幹部骨軟部腫瘍における術前塞栓術の有用性に関する検討

    岡本 大佑, 牛島 泰宏, 藤田 展宏, 石松 慶祐, 村山 僚, 糸山 昌宏, 松本 嘉寛, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌  2023.4  (一社)日本インターベンショナルラジオロジー学会

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  • 小径腎細胞癌に対して凍結療法を施行した後期高齢者の治療後経過についての検討

    牛島 泰宏, 岡本 大佑, 藤田 展宏, 石松 慶祐, 村山 僚, 糸山 昌宏, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌  2023.4  (一社)日本インターベンショナルラジオロジー学会

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  • 埋込型LVAD(補助人工心臓)装着患者の腎細胞癌に対して凍結療法を施行した1例

    西村 俊輔, 岡本 大佑, 牛島 泰宏, 藤田 展宏, 石松 慶祐, 村山 僚, 糸山 昌宏, 石神 康生

    Japanese Journal of Radiology  2024.2  (公社)日本医学放射線学会

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  • 切除不能膵頭部癌の治療経過中に仮性動脈瘤を形成し,血管塞栓術・ステントグラフト留置術により治療し得た2例

    麻生 皆人, 小森 康寛, 木村 弥成子, 大野 彰久, 松本 一秀, 村上 正俊, 寺松 克人, 竹野 歩, 植田 圭二郎, 藤森 尚, 藤田 展宏, 牛島 泰宏, 小川 佳宏

    日本消化器病学会九州支部例会・日本消化器内視鏡学会九州支部例会プログラム・抄録集  2022.12  日本消化器病学会-九州支部

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  • メラニン色素沈着を伴う腟原発血管周囲類上皮細胞腫瘍(PEComa)の1例

    今福 輝, 和田 憲明, 藤田 展宏, 牛島 泰宏, 石松 慶祐, 高尾 誠一朗, 石神 康生, 川久保 尚徳, 安永 昌史, 小田 義直

    Japanese Journal of Radiology  2024.2  (公社)日本医学放射線学会

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  • ポリープ状の形態を呈した腎細胞癌胆嚢転移の1例

    安部 時子, 藤田 展宏, 牛島 泰宏, 高山 幸久, 石松 慶祐, 石神 康生, 西江 昭弘, 久保 雄一郎, 門司 恵介, 古賀 裕

    Japanese Journal of Radiology  2023.2  (公社)日本医学放射線学会

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  • ガドキセト酸造影MRIを用いた葉切除後の肝再生術前予測の有用性(Value of Gadoxetic Acid-enhanced MR Imaging for Preoperative Prediction of Future Liver Regeneration after Hemihepatectomy)

    Fujita Nobuhiro, Ushijima Yasuhiro, Okamoto Daisuke, Ishimatsu Keisuke, Murayama Ryo, Itoyama Masahiro, Harada Noboru, Ishigami Kousei

    日本医学放射線学会学術集会抄録集  2023.3  (公社)日本医学放射線学会

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  • Von-Hippel-Lindau病に生じた腎細胞癌に対する凍結療法 腫瘍制御と腎機能についての後ろ向き研究(Cryoablation for Renal Cell Carcinoma in Patients with Von-Hippel-Lindau Disease: A Retrospective Analysis of Tumor Control and Renal Function)

    Ushijima Yasuhiro, Okamoto Daisuke, Fujita Nobuhiro, Ishimatsu Keisuke, Itoyama Masahiro, Tabata Kousuke, Ishigami Kousei

    日本医学放射線学会学術集会抄録集  2024.3  (公社)日本医学放射線学会

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  • Dual-layer spectral CTで評価した細胞外容積分画を用いた進行胃癌における術前補助化学療法の病理学的効果の予測(Prediction of pathological response to neoadjuvant chemotherapy for advanced gastric cancer using extracellular volume fraction determined by dual-layer spectral CT)

    西牟田 雄祐, 鶴丸 大介, 藤田 展宏, 甲斐 聖広, 南條 勝哉, 牛島 泰宏, 沖 英次, 石神 康生

    日本医学放射線学会秋季臨床大会抄録集  2022.9  (公社)日本医学放射線学会

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  • Dual layer spectral CTの仮想単純CT 副腎腺腫における信頼性

    高山 幸久, 西江 昭弘, 牛島 泰宏, 石松 慶祐, 浅山 良樹, 中山 智博, 久保 雄一郎

    Japanese Journal of Radiology  2022.2  (公社)日本医学放射線学会

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  • CT-Extracellular volumeによる膵管癌の術前化学療法の効果予測の可能性(CT Extracellular Volume Fraction of Pancreatic Ductal Adenocarcinoma: Possible Role to Predict the Efficacy of Preoperative Neoadjuvant Chemotherapy)

    Fujita Nobuhiro, Ushijima Yasuhiro, Ishimatsu Keisuke, Wada Noriaki, Takao Seiichiro, Fujimori Nao, Nakata Kohei, Oda Yoshinao, Ishigami Kousei

    日本医学放射線学会学術集会抄録集  2022.3  (公社)日本医学放射線学会

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MISC

  • 【肝胆膵のcommon diseaseにみる非典型的画像所見】膵漿液性嚢胞腫瘍(SCN)

    牧瀬 智, 藤田 展宏, 中山 智博, 牛島 泰宏, 岡本 大佑, 石松 慶祐, 田畑 公佑, 石神 康生

    画像診断   44 ( 12 )   1202 - 1208   2024.9   ISSN:0285-0524

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    <文献概要>Point●膵漿液性嚢胞腫瘍(SCN)は基本的には良性腫瘍であり,他の悪性ポテンシャルをもつ膵腫瘍性病変との鑑別が重要である.●SCNの中で頻度が高いのは,microcystic typeとmixed typeである.microcystic typeはSCNの典型像とされ,血流豊富な隔壁を伴う蜂巣状構造(honeycombed appearance)を呈する嚢胞性病変である.●SCNの非典型例として,macrocystic(oligocystic)type,solid typeがある.●macrocystを伴うSCNでは膵粘液性嚢胞腫瘍(MCN)や膵管内乳頭粘液性腫瘍(IPMN)との鑑別,microcystic typeやsolid typeのSCNでは膵神経内分泌腫瘍(PNEN)との鑑別が重要である.

  • 【日常診療での超音波検査のおさえどころ】日常診療での超音波検査 腎臓

    木村 知子, 牛島 泰宏, 小宮 勲, 加藤 豊幸, 石神 康生

    臨牀と研究   101 ( 7 )   817 - 823   2024.7   ISSN:0021-4965

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  • 症候性子宮筋腫に対する子宮動脈塞栓術(UAE)ガイドライン2021

    山上 卓士, 矢田 晋作, 浅野 仁覚, 足立 憲, 石川 源, 泉 雄一郎, 上嶋 英介, 大内 泰文, 加藤 仁美, 桑鶴 良平, 駒田 智大, 杉山 宗弘, 清治 和将, 曽根 美雪, 谷川 昇, 東原 大樹, 松本 知博, 村上 優, 森田 賢, 阿部 壮一郎, 池田 秀次, 伊東 伸剛, 遠藤 雅之, 岡田 浩章, 小黒 草太, 小野 祐介, 片山 大輔, 河合 剛, 岸本 健太郎, 木村 慎太郎, 木村 廉, 小谷 美香, 坂本 篤彦, 下平 政史, 曽田 昌弘, 高杉 昌平, 田中 会秀, 棚橋 裕吉, 塚本 和充, 永井 啓介, 中村 純寿, 濱本 耕平, 本行 秀成, 松井 裕輔, 松永 望, 宮崎 将也, 山本 修一, 山本 貴浩, 勝盛 哲也, 木村 正, 鈴木 直, 掛田 伸吾, 小泉 淳, 蘆田 浩一, 石川 雅基, 石山 公一, ウッドハムス 玲子, 魚谷 健祐, 牛島 泰宏, 江頭 秀哲, 扇 尚弘, 大田 信一, 梶原 賢司, 粕谷 秀輔, 我那覇 文清, 元津 倫幸, 高良 真一, 小金丸 雅道, 米虫 敦, 佐藤 塁, 清水 勧一朗, 塚田 実郎, 土谷 飛鳥, 富田 康介, 中井 資貴, 中村 一彦, 野口 智幸, 橋田 和靖, 橋本 政幸, 伴野 辰雄, 東出 高至, 古市 欣也, 松井 洋, 三浦 剛史, 本橋 健司, 保本 卓, 山添 真治, 日本IVR学会, 症候性子宮筋腫に対する子宮動脈塞栓術(UAE)ガイドライン2021作成委員会, 日本IVR学会ガイドライン委員会

    日本インターベンショナルラジオロジー学会雑誌   36 ( 4 )   365 - 401   2022.12   ISSN:1340-4520

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  • 【生検 最近の潮流】軟部腫瘍診療における生検と画像診断の役割

    鷺山 幸二, 神谷 武志, 山崎 誘三, 樋田 知之, 松浦 由布子, 藪内 英剛, 牛島 泰宏, 石神 康生

    日本インターベンショナルラジオロジー学会雑誌   36 ( 2 )   119 - 125   2022.3   ISSN:1340-4520

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    軟部腫瘍の発生部位は四肢をはじめ全身に及び、皮下や筋間、筋肉、後腹膜など深度も様々である。良性腫瘍、中間悪性腫瘍、希少癌の悪性軟部腫瘍に分けられる。診断は病理診断により確定されるが、不適切な生検手技は患者の予後を悪化させる。軟部腫瘍の病理診断と根治的治療の手術に関して簡単に述べ、現在大きな問題になっている無計画切除に言及した。各生検技法の概要と注意点を述べ、その補助となる画像モダリティーの特徴を解説した。画像ガイド下針生検が奏効した症例を紹介した。

  • 腎細胞癌の凍結療法

    牛島 泰宏, 浅山 良樹, 西江 昭弘, 石神 康生, 高山 幸久, 岡本 大佑, 藤田 展宏, 森田 孝一郎, 横溝 晃, 内藤 誠二, 本田 浩

    2014.9

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  • 「感染症の画像診断:早期診断・早期治療につなげる」 腹部感染症 上腹部実質臓器・消化管

    牛島泰宏、西江昭弘、浅山良樹、石神康生、柿原大輔、高山幸久、藤田展宏、本田 浩

    臨床画像   2013.4

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  • ER必携、急性腹症の画像診断 ―出血―

    牛島泰宏、田嶋強、西江昭弘、石神康生、柿原大輔、岡本大佑、本田浩

    画像診断   2008.12

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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Professional Memberships

  • Japanese Society for Magnetic Resonance in Medicine

  • The Japanese Society of interventional Radiology

  • Japan Radiological Society

Committee Memberships

  • 第60回日本医学放射線学会秋季学術集会   Steering committee member   Domestic

    2024.10   

  • 第83回日本医学放射線学会   Steering committee member   Domestic

    2024.4   

  • 日本IVR学会   Councilor   Domestic

    2024.1 - Present   

  • 日本IVR学会   Councilor   Domestic

    2024.1 - Present   

  • 第52回日本IVR学会総会   Steering committee member   Domestic

    2023.5   

  • 第82回日本医学放射線学会   Steering committee member   Domestic

    2023.4   

  • 日本医学放射線学会   Councilor   Domestic

    2022.4 - Present   

  • 日本医学放射線学会   Councilor   Domestic

    2022.4 - 2024.3   

  • 日本医学放射線学会九州地方会   世話人   Domestic

    2021.6 - Present   

  • 日本医学放射線学会九州地方会   世話人   Domestic

    2021.6 - 2023.3   

  • 第193回日本医学放射線学会九州地方会   事務局代表   Domestic

    2021.6   

  • 九州IVR研究会   世話人   Domestic

    2020.2 - 2022.3   

  • 日本IVR学会   Councilor   Domestic

    2014.1 - Present   

  • 日本IVR学会   Councilor   Domestic

    2014.1 - 2022.3   

  • 日本IVR学会   Councilor   Domestic

    2014.1 - 2019.3   

  • 日本IVR学会   代議員   Domestic

    2013.10 - 2015.3   

  • 第72回日本医学放射線学会総会   実行委員 / プログラム委員   Domestic

    2012.5 - 2013.4   

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Academic Activities

  • 座長

    第60回日本医学放射線学会秋季学術集会  ( Japan ) 2024.10

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    Type:Competition, symposium, etc. 

  • 座長

    第52回日本IVR学会総会  ( Japan ) 2023.5

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    第49回 日本IVR学会  ( Japan ) 2020.8

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    第48回 日本IVR学会  ( Japan ) 2019.5 - 2019.6

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    九州IVR研究会  ( Japan ) 2015.12

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    九州IVR研究会  ( Japan ) 2014.12

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    九州IVR地方会  ( Japan ) 2013.12

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    Type:Competition, symposium, etc. 

  • 座長(Chairmanship)

    176回 日本医学放射線学会 九州地方会  ( Japan ) 2013.1

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    Type:Competition, symposium, etc. 

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Research Projects

  • 複合現実(MR)・仮想現実(VR)を利用したCTガイド下IVRの開発

    Grant number:25K10892  2025.4 - 2028.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    牛島 泰宏

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    Grant type:Scientific research funding

    CiNii Research

  • 膵の硬度測定による病態解析の試み

    Grant number:24K10890  2024.4 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    石神 康生, 岡本 大佑, 石松 慶祐, 糸山 昌宏, 藤田 展宏, 牛島 泰宏, 藤森 尚

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    Grant type:Scientific research funding

    深部臓器である膵の硬さを体外から測定することは困難とされ、膵の硬さを体外から計測する手法は確立されていない。慢性膵炎は膵実質の脱落・線維化が生じる不可逆的な病態であるが、早期慢性膵炎の段階で膵の硬化・線維化がすでに生じているとされる。
    本研究では、臨床で広く普及しているCTを用いて膵の硬さ(線維化)を測定し病態解析を行う。膵の線維化は細胞外スペースの増加に反映されるので、dual energy CTで測定される細胞外液量から膵線維化を推定し、早期慢性膵炎の低侵襲的な診断法を確立する。この研究は、膵内分泌機能・外分泌機能のバイオマーカーや癌の悪性度診断、術後合併症の予測などへの応用が期待できる。

    CiNii Research

  • APTイメージングを用いた膵臓嚢胞性病変の診断の有用性の確立

    Grant number:22K07641  2022.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    石松 慶祐, 石神 康生, 藤田 展宏, 牛島 泰宏

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    Grant type:Scientific research funding

    膵臓ののう胞性病変は診断によって経過観察で問題のないものや手術の必要なものがありますが、従来のCTやMRIなど画像では診断や悪性度の推定が難しい場合があります。本研究では、タンパク濃度を反映した画像が得られる新たなMRIの撮影法(APTイメージング)を用いて、これらをより高い精度で見分けるための新たな診断法を確立すること目指します。

    CiNii Research

  • マルチパラメトリックMRIを用いた肝再生の評価・予測モデルの確立

    Grant number:21K07676  2021.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    藤田 展宏, 石神 康生, 西江 昭弘, 石松 慶祐, 牛島 泰宏

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    Grant type:Scientific research funding

    肝臓は体内最大の代謝器官であり、きわめて高い再生能力を持つ。肝切除術後や肝障害による肝細胞喪失時に肝再生が起こるが、不十分な肝再生は肝不全の原因となるため、治療前に肝再生を予測できれば方針決定に寄与する。MRIには肝機能や組織学的な肝実質の炎症・線維化、肝再生に関与しうる微小環境(脂肪・鉄沈着量やタンパク量)を評価できる種々のパラメーターが存在し、肝再生に伴う肝実質の変化を包括的に評価することが可能である。本研究では、肝再生が重要である様々な臨床状況において、肝再生に伴うMRIパラメーターの変化を観察し、肝再生の新たな評価法を確立し、肝再生の予測モデルを確立することを目的とする。

    CiNii Research

  • Development of novel quantitative analysis of liver fibrosis and function using MRI

    Grant number:20K08028  2020.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    高山 幸久, 久保 雄一郎, 西江 昭弘, 石松 慶祐, 牛島 泰宏

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    Grant type:Scientific research funding

    造影および非造影MRIを用いた肝線維化評価や肝細胞機能評価の有用性はこれまで複数報告されているが、標準となる定量的評価法が確立できていない。その為、異なる評価者間や異なる施設間における診断能の再現性が乏しい。本研究によって、我々の定量的画像診断法が、将来的にその問題点を解決する手法となりえると考えている。これまで我々が行った研究により、本研究に必要なMRI撮像プロトコールは確立した。今後行うべき検討として、①肝線維化診断や肝細胞機能評価に関する画像解析法の検証、および問題点の改善、②再現性および精度の高い画像診断法(診断能)の検証である。

    CiNii Research

  • Establishment of a prediction method for tumor grade and patients' prognosis in hepatocellular carcinoma based on APT imaging

    Grant number:20K08083  2020.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Nishie Akihiro

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    Grant type:Scientific research funding

    When we summarize the study results, the following three conclusions can be made: (1) the optimal presaturation pulse time is 250 msec, (2) the APT signal of focal nodular hyperplasias may show a high value (however, it is necessary to accumulate more cases in the future), (3) The APT signal in the liver parenchyma may reflect liver function, fibrosis and necro-inflammation from the viewpoint of protein synthesis. As we proceeded with the development of the sequence, we were concerned about the accuracy of analysis for small lesions due to the stability of the image quality of APT imaging. Therefore, we decided to evaluate only large liver tumors. This limited the enrollment of cases with hepatocellular carcinoma.

    CiNii Research

  • 拡張現実(AR)を利用した腎細胞癌に対するCTガイド下凍結療法の開発

    Grant number:20K07999  2020 - 2024

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    牛島 泰宏, 久保 雄一郎, 西江 昭弘, 石松 慶祐, 高山 幸久

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    Authorship:Principal investigator  Grant type:Scientific research funding

    画像下治療の一つである腎細胞癌に対するCTガイド下凍結療法は、外科的治療と比較と比べ低侵襲であり、画像装置の発達に伴い近年急速に普及してきた治療法である。治療前には種々の画像装置の利用により膨大な画像情報が生じるが、実際の治療を行う際の画像は二次元情報のみで分解能も高くなく十分な情報とは言えない。そこで、本研究の目的は、膨大な画像情報を治療時に視覚的にわかりやすい形で提供する手段としてAR(Augmented reality、拡張現実)を利用し、より質の高い低侵襲で安全な腎細胞癌に対するCTガイド下凍結療法を開発することである

    CiNii Research

  • Development of imaging methods to predict genomic and molecular abnormalities for personalized treatment of biliary tract cancer.

    Grant number:19K08176  2019.4 - 2023.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Asayama Yoshiki

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    Grant type:Scientific research funding

    First, we investigated the optimal reconstruction method of CT cholangiography for the evaluation of biliary tract cancer in ultra-high resolution CT. The reconstruction methods used were AiCE (Advanced intelligent Clear-IQ Engine), FIRST (Forward projected model-based Iterative Reconstruction SoluTion), and AIDR (Adaptive Iterative Dose Reduction)-3D, of which AiCE was the best. Next, we examined the optimal reconstruction method for CT using low-iodine contrast media in patients with poor renal function. The AiCE reconstruction method was superior to the conventional method.

    CiNii Research

  • Radiation dosimetry of Interventional radiological operator using direct eye dosimeter corresponding to new radiation dose limit of ICRP

    Grant number:18K07755  2018.4 - 2023.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Hirakawa Masakazu

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    Grant type:Scientific research funding

    In this research, there was no IR (interventional radiology) operators who evaluated the lens dose with neck glass dosimeter outside protective lead glasses and exceed the new occupational lens dose limit (20 mSv/year, averaged over defined periods of 5 years). In high volume center of IR, however, there may be some IR operators who may exceed the new occupational lens dose limit. The lens dose inside lead glasses which was estimated with the shieling effect and the lens dose of neck dosimeter tended to be lower and underestimated, compared to the eye lens dose by using a novel direct eye dosimeter, the DOSIRIS(Hp(3)) under protective glasses. This underestimated eye lens dose may cause the risk of radiation induced cataracts. Finally, To comply with new limit of eye dose and minimize the radiation-induced risk at the eye lenses, protective lead devices and correct evaluation of the eye dose using direct eye dosimeter like DOSIRIS under protective lead glasses might be needed.

    CiNii Research

  • 大動脈ステント留置後のエンドリークに対する新たな診断法とテーラーメード治療の開発

    Grant number:17K10446  2017 - 2019

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

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Educational Activities

  • 1 医学部6年生(クリニカルクラークシップ)に対する、腹部領域のCT/MRI検査のレポート作成の指導および画像診断の教育、血管造影をはじめとしたIVRの手技の指導、教育
    2 研修医・臨床大学院生に対する、放射線業務、腹部領域の画像診断学、レポート作成、IVRの指導
    3 医学部3年生に対する放射線医学(IVR領域)の講義を行っている
    4 系統講義(肝、胆、膵の画像診断)の講義を行っている

Class subject

  • 3学年後期科目、肝胆膵

    2024.10 - 2025.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2024.4 - 2025.3   Full year

  • 3学年 医系医学Ⅳ 放射線医学

    2024.4 - 2025.3   First semester

  • 3学年後期科目、肝胆膵

    2023.10 - 2024.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2023.4 - 2024.3   Full year

  • 3学年 医系医学Ⅳ 放射線医学

    2023.4 - 2023.9   First semester

  • 3学年後期科目、肝胆膵

    2022.10 - 2023.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2022.4 - 2023.3   Full year

  • 4学年 医系医学Ⅳ 放射線医学

    2022.4 - 2022.9   First semester

  • 3学年後期科目、肝胆膵

    2021.10 - 2022.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2021.4 - 2022.3   Full year

  • 4学年 医系医学Ⅳ 放射線医学

    2021.4 - 2021.9   First semester

  • 3学年後期科目、肝胆膵

    2020.10 - 2021.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2020.4 - 2021.3   Full year

  • 4学年 医系医学Ⅳ 放射線医学

    2020.4 - 2020.9   First semester

  • 3学年後期科目、肝胆膵

    2019.10 - 2020.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2019.4 - 2020.3   Full year

  • 4学年 医系医学Ⅳ 放射線医学

    2019.4 - 2019.9   First semester

  • 3学年後期科目、肝胆膵

    2018.10 - 2019.3   Second semester

  • 臨床医学実習における腹部単純写真の読み方についての講義

    2018.10 - 2019.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2018.4 - 2019.3   Full year

  • 臨床医学実習における腹部単純写真の読み方についての講義

    2017.10 - 2018.3   Second semester

  • CCSにおけるIVR,CT,MRIの実習および講義

    2017.4 - 2018.3   Full year

  • CCSにおけるIVR,CT,MRIの実習および講義

    2016.4 - 2017.3   Full year

  • CCSでのCT,MRI,IVR指導

    2015.4 - 2016.3   Full year

  • 3学年後期科目、肝胆膵

    2014.10 - 2015.3   Second semester

  • CCSでのCT,MRI,IVR指導

    2014.4 - 2015.3   Full year

  • 3学年後期科目、肝胆膵

    2012.10 - 2013.3   Second semester

  • CCSでのCT,MRI,IVR指導

    2012.4 - 2013.3   Full year

  • CCSでのCT,MRI,IVR指導

    2011.4 - 2012.3   Full year

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Outline of Social Contribution and International Cooperation activities

  • 腹部領域の画像診断およびIVRに関して、放射線科医や放射線技師を対象とした研究会や講習会で、教育講演を行っている
    (福岡レントゲンアーベント、福岡IVR研究会の開催)
    国際学会における学術発表

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Internal Medicine / Radiology

Clinician qualification

  • Specialist

    Japan Radiological Society(JRS)

  • Specialist

    日本血管造影・インターベンショナルラジオロジー学会

Year of medical license acquisition

  • 1998

Notable Clinical Activities

  • 画像誘導下の低侵襲治療 肝細胞癌に対する血管内治療 緊急止血に対する塞栓術 経皮的焼却術 腎細胞癌に対する経皮的凍結療法 大動脈ステント留置後のエンドリークに対する経皮的塞栓術 CTガイド下生検・ドレナージ