Homologous Recombination Repair Gene Alterations Are Associated with Tumor Mutational Burden and Survival of Immunotherapy Reviewed International journal

Mamoru Ito, Makoto Kubo, Hitomi Kawaji, Yoshiki Otsubo, Kanako Kurata, Hikaru Abutani, Mikita Suyama, Yoshinao Oda, Tomoharu Yoshizumi, Masafumi Nakamura, Eishi Baba

Cancers   2023.11

Case Report: Resolution of remitting seronegative symmetrical synovitis with pitting edema during nivolumab therapy for gastric cancer

Hirofumi Ohmura, Moe Kondo, Masato Uenomachi, Hiroshi Ariyama, Mamoru Ito, Kenji Tsuchihashi, Masahiro Ayano, Hiroaki Niiro, Koichi Akashi, Eishi Baba

Frontiers in Oncology   13   2023.10

Survival outcomes including salvage therapy of adult head and neck para-meningeal rhabdomyosarcoma: a multicenter retrospective study from Japan

Kenji Tsuchihashi, Mamoru Ito, Shuji Arita, Hitoshi Kusaba, Wataru Kusano, Takashi Matsumura, Takafumi Kitazono, Shohei Ueno, Ryosuke Taguchi, Tomoyasu Yoshihiro, Yasuhiro Doi, Kohei Arimizu, Hirofumi Ohmura, Tatsuhiro Kajitani, Kenta Nio, Michitaka Nakano, Kotoe Oshima, Shingo Tamura, Tsuyoshi Shirakawa, Hozumi Shimokawa, Keita Uchino, Fumiyasu Hanamura, Yuta Okumura, Masato Komoda, Taichi Isobe, Hiroshi Ariyama, Taito Esaki, Kazuki Hashimoto, Noritaka Komune, Mioko Matsuo, Keiji Matsumoto, Kaori Asai, Tadamasa Yoshitake, Hidetaka Yamamoto, Yoshinao Oda, Koichi Akashi, Eishi Baba

BMC Cancer   23 ( 1 )   2023.10

Intraosseous synovial sarcoma of the mandible: A case report and review of the literature. International journal

Ikumi Imajo, Tomohiro Yamada, Toru Chikui, Tamotsu Kiyoshima, Mamoru Ito, Kenichi Kohashi, Eiji Sakamoto, Yoshinao Oda

Oncology letters   26 ( 1 )   318 - 318   2023.7

Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan

Yoichi Naito, Kuniko Sunami, Hidenori Kage, Keigo Komine, Toraji Amano, Mitsuho Imai, Takafumi Koyama, Daisuke Ennishi, Masashi Kanai, Hirotsugu Kenmotsu, Takahiro Maeda, Sachi Morita, Daisuke Sakai, Kousuke Watanabe, Hidekazu Shirota, Ichiro Kinoshita, Masashiro Yoshioka, Nobuaki Mamesaya, Mamoru Ito, Shinji Kohsaka, Yusuke Saigusa, Kouji Yamamoto, Makoto Hirata, Katsuya Tsuchihara, Takayuki Yoshino

JAMA Network Open   5 ( 12 )   e2245081 - e2245081   2022.12

IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous thromboembolism. International journal

Hitoshi Kusaba, Shohei Moriyama, Michinari Hieda, Mamoru Ito, Hirofumi Ohmura, Taichi Isobe, Kenji Tsuchihashi, Mitsuhiro Fukata, Hiroshi Ariyama, Eishi Baba

Japanese journal of clinical oncology   52 ( 10 )   1183 - 1190   2022.10

希少がんの治療戦略 信頼と絆に基づく肉腫のチーム医療

遠藤 誠, 土橋 賢司, 松本 嘉寛, 坂本 節子, 鍋島 央, 飯田 圭一郎, 藤原 稔史, 伊東 守, 磯部 大地, 有山 寛, 赤司 浩一, 馬場 英司, 中島 康晴

日本癌治療学会学術集会抄録集   60回   WS15 - 3   2022.10

Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model.

Kyoko Yamaguchi, Tomoyasu Yoshihiro, Hiroshi Ariyama, Mamoru Ito, Michitaka Nakano, Yuichiro Semba, Jumpei Nogami, Kenji Tsuchihashi, Takuji Yamauchi, Shohei Ueno, Taichi Isobe, Koji Shindo, Taiki Moriyama, Kenoki Ohuchida, Masafumi Nakamura, Yoshihiro Nagao, Tetsuo Ikeda, Makoto Hashizume, Hiroyuki Konomi, Takehiro Torisu, Takanari Kitazono, Tomohiro Kanayama, Hiroyuki Tomita, Yoshinao Oda, Hitoshi Kusaba, Takahiro Maeda, Koichi Akashi, Eishi Baba

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   25 ( 5 )   862 - 878   2022.9

Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions Reviewed International journal

Mamoru Ito, Michitaka Nakano, Hiroshi Ariyama, Kyoko Yamaguchi, Risa Tanaka, Yuichiro Semba, Takeshi Sugio, Kohta Miyawaki, Yoshikane Kikushige, Shinichi Mizuno, Taichi Isobe, Kenro Tanoue, Ryosuke Taguchi, Shohei Ueno, Takahito Kawano, Masaharu Murata, Eishi Baba, Koichi Akashi

Cancer Letters   2022.2

Alveolar soft part sarcoma of the orbit: A case report

Takeshi Oda, Kazufumi Kikuchi, Osamu Togao, Shingo Baba, Masahiro Mizoguchi, Mika Tanabe, Mamoru Ito, Hidetaka Yamamoto, Kousei Ishigami, Akio Hiwatashi

Radiology Case Reports   16 ( 12 )   3766 - 3771   2021.12

Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients? International journal

Eijiro Shimada, Makoto Endo, Yoshihiro Matsumoto, Kenji Tsuchihashi, Mamoru Ito, Hitoshi Kusaba, Akira Nabeshima, Tomoya Nawata, Akira Maekawa, Tomoya Matsunobu, Nokitaka Setsu, Toshifumi Fujiwara, Keiichiro Iida, Makoto Nakagawa, Takeshi Hirose, Masaya Kanahori, Ryunosuke Oyama, Taichi Isobe, Hiroshi Ariyama, Kenichi Kohashi, Hidetaka Yamamoto, Yoshinao Oda, Yukihide Iwamoto, Koichi Akashi, Eishi Baba, Yasuharu Nakashima

Journal of clinical medicine   10 ( 21 )   2021.10

Improvement in recurring nivolumab-induced pneumonitis with repetitive administration of infliximab in a patient with head and neck cancer: A case report. International journal

Shohei Ueno, Masato Uenomachi, Hitoshi Kusaba, Mamoru Ito, Kunihiro Suzuki, Hirofumi Ohmura, Kenji Tsuchihashi, Hiroshi Ariyama, Koichi Akashi, Eishi Baba

Molecular and clinical oncology   15 ( 4 )   221 - 221   2021.10

[Development of Cancer Genomic Medicine in Kyushu Region and the Roles of Kyushu University Hospital as a Core Hospital for Cancer Genomic Medicine].

Mamoru Ito, Eishi Baba

Gan to kagaku ryoho. Cancer & chemotherapy   48 ( 7 )   873 - 877   2021.7

Prominent PD-L1-positive M2 macrophage infiltration in gastric cancer with hyper-progression after anti-PD-1 therapy: A case report. International journal

Kyoko Yamaguchi, Kenji Tsuchihashi, Kunihiro Tsuji, Yosuke Kito, Kenro Tanoue, Hirofumi Ohmura, Mamoru Ito, Taichi Isobe, Hiroshi Ariyama, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Medicine   100 ( 19 )   e25773   2021.5

Predictive impact of C-reactive protein to albumin ratio for recurrent or metastatic head and neck squamous cell carcinoma receiving nivolumab. International journal

Kenro Tanoue, Shingo Tamura, Hitoshi Kusaba, Yudai Shinohara, Mamoru Ito, Kenji Tsuchihashi, Tsuyoshi Shirakawa, Taiga Otsuka, Hirofumi Ohmura, Taichi Isobe, Hiroshi Ariyama, Sakuya Koreishi, Yuzo Matsushita, Hozumi Shimokawa, Risa Tanaka, Kenji Mitsugi, Koichi Akashi, Eishi Baba

Scientific reports   11 ( 1 )   2741 - 2741   2021.2

Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin. International journal

Kenji Tsuchihashi, Hitoshi Kusaba, Tomoyasu Yoshihiro, Toshifumi Fujiwara, Nokitaka Setsu, Makoto Endo, Yoshihiro Matsumoto, Takashi Imajima, Yudai Shinohara, Mamoru Ito, Satoru Yamaga, Kenro Tanoue, Kohei Arimizu, Hirofumi Ohmura, Fumiyasu Hanamura, Kyoko Yamaguchi, Taichi Isobe, Hiroshi Ariyama, Yasuharu Nakashima, Koichi Akashi, Eishi Baba

Scientific reports   10 ( 1 )   20896 - 20896   2020.12

RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells

Nobuhiro Tsuruta, Kenji Tsuchihashi, Hirofumi Ohmura, Kyoko Yamaguchi, Mamoru Ito, Hiroshi Ariyama, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Biochemical and Biophysical Research Communications   530 ( 1 )   235 - 239   2020.9

Exploratory retrospective study of risk factors for thromboembolism treated with multi-kinase inhibitor pazopanib or lenvatinib

Kenta Nio, Kenji Tsuchihashi, Keisuke Taguchi, Tomoyasu Yoshihiro, Kyoko Yamaguchi, Mamoru Ito, Shohei Moriyama, Mitsuhiro Fukata, Toshifumi Fujiwara, Nokitaka Setsu, Makoto Endo, Yoshihiro Matsumoto, Yasuharu Nakashima, Takahiro Wakasaki, Ryuji Yasumatsu, Hiroshi Ariyama, Hitoshi Kusaba, Junji Kishimoto, Koichi Akashi, Eishi Baba

INTERNATIONAL JOURNAL OF SURGERY-ONCOLOGY   5 ( 4 )   2020.8

FoundationOne CDxによる進行大腸癌患者の遺伝子変異解析

倉田 加奈子, 久保 真, 永井 俊太郎, 藤田 逸人, 土橋 賢司, 有山 寛, 永吉 絹子, 貞苅 良彦, 川地 眸, 甲斐 昌也, 伊東 守, 山元 英崇, 小田 義直, 馬場 英司, 中村 雅史

日本外科学会定期学術集会抄録集   120回   SF - 5   2020.8

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody. International journal

Hirofumi Ohmura, Kyoko Yamaguchi, Fumiyasu Hanamura, Mamoru Ito, Akitaka Makiyama, Keita Uchino, Hozumi Shimokawa, Shingo Tamura, Taito Esaki, Kenji Mitsugi, Yoshihiro Shibata, Hisanobu Oda, Kenji Tsuchihashi, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba

British journal of cancer   122 ( 10 )   1507 - 1517   2020.5

Activation of memory/effector T cells and association between prognosis and OX40-positive T cells in advanced head and neck cancer patients treated with anti-programmed death-1 antibody.

Hirofumi Ohmura, Kyoko Yamaguchi, Fumiyasu Hanamura, Tanoue Kenrou, Shiho Kawagoe, Kohei Arimizu, Yuzo Matsushita, Tatsuhiro Kajitani, Shingo Tamura, Hozumi Shimokawa, Keita Uchino, Hisanobu Oda, Yudai Shinohara, Mamoru Ito, Kenji Tsuchihashi, Taichi Isobe, Hiroshi Ariyama, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Journal of Clinical Oncology   38 ( 5_suppl )   35 - 35   2020.2

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer. International journal

Hirofumi Ohmura, Mamoru Ito, Keita Uchino, Chihiro Okada, Shigeki Tanishima, Yuichi Yamada, Seiya Momosaki, Masato Komoda, Miyuki Kuwayama, Kyoko Yamaguchi, Yuta Okumura, Michitaka Nakano, Kenji Tsuchihashi, Taichi Isobe, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba

FEBS open bio   10 ( 1 )   147 - 157   2020.1

Efficacy and safety of ramucirumab plus modified FOLFIRI for metastatic colorectal cancer.

Tomoyasu Yoshihiro, Hitoshi Kusaba, Akitaka Makiyama, Kazuma Kobayashi, Masato Uenomachi, Mamoru Ito, Yasuhiro Doi, Kenji Mitsugi, Tomomi Aikawa, Kotoe Takayoshi, Taito Esaki, Hozumi Shimokawa, Kenji Tsuchihashi, Hiroshi Ariyama, Koichi Akashi, Eishi Baba

International journal of clinical oncology   24 ( 5 )   508 - 515   2019.5

Activation of central/effector memory T cells in advanced gastric cancer patients treated with antiprogrammed death-1 antibody.

Hirofumi Ohmura, Kyoko Yamaguchi, Fumiyasu Hanamura, Mamoru Ito, Akitaka Makiyama, Keita Uchino, Hozumi Shimokawa, Taito Esaki, Kenji Mitsugi, Yoshihiro Shibata, Hisanobu Oda, Kenji Tsuchihashi, Hiroshi Ariyama, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Journal of Clinical Oncology   37 ( 4_suppl )   54 - 54   2019.2

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer. International journal

Michitaka Nakano, Yoshikane Kikushige, Kohta Miyawaki, Yuya Kunisaki, Shinichi Mizuno, Katsuto Takenaka, Shingo Tamura, Yuta Okumura, Mamoru Ito, Hiroshi Ariyama, Hitoshi Kusaba, Masafumi Nakamura, Takahiro Maeda, Eishi Baba, Koichi Akashi

Oncogene   38 ( 6 )   780 - 793   2019.2

Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer. International journal

Kenji Tsuchihashi, Mamoru Ito, Toshikazu Moriwaki, Shota Fukuoka, Hiroya Taniguchi, Atsuo Takashima, Yosuke Kumekawa, Takeshi Kajiwara, Kentaro Yamazaki, Taito Esaki, Akitaka Makiyama, Tadamichi Denda, Hironaga Satake, Takeshi Suto, Naotoshi Sugimoto, Kenji Katsumata, Toshiaki Ishikawa, Tomomi Kashiwada, Eiji Oki, Yoshito Komatsu, Hiroyuki Okuyama, Daisuke Sakai, Hideki Ueno, Takao Tamura, Kimihiro Yamashita, Junji Kishimoto, Yasuhiro Shimada, Eishi Baba

Clinical colorectal cancer   17 ( 4 )   e687-e697   2018.12

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer. International journal

Michitaka Nakano, Mamoru Ito, Risa Tanaka, Hiroshi Ariyama, Kenji Mitsugi, Akitaka Makiyama, Keita Uchino, Taito Esaki, Nobuhiro Tsuruta, Fumiyasu Hanamura, Kyoko Yamaguchi, Yuta Okumura, Kosuke Sagara, Kotoe Takayoshi, Kenta Nio, Kenji Tsuchihashi, Shingo Tamura, Hozumi Shimokawa, Shuji Arita, Kohta Miyawaki, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Cancer science   109 ( 11 )   3461 - 3470   2018.11

The risk factors for oxaliplatin-induced peripheral sensory neuropathy and thrombocytopenia in advanced gastric cancer. International journal

Kyoko Yamaguchi, Hitoshi Kusaba, Akitaka Makiyama, Kenji Mitsugi, Keita Uchino, Shingo Tamura, Yoshihiro Shibata, Taito Esaki, Mamoru Ito, Kotoe Takayoshi, Kenji Tsuchihashi, Shuji Arita, Hiroshi Ariyama, Koichi Akashi, Eishi Baba

Cancer chemotherapy and pharmacology   82 ( 4 )   625 - 633   2018.10

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody. International journal

Kyoko Yamaguchi, Koji Mishima, Hirofumi Ohmura, Fumiyasu Hanamura, Mamoru Ito, Michitaka Nakano, Kenji Tsuchihashi, Shun-Ichiro Ota, Naoko Wada, Hiroshi Uchi, Hiroshi Ariyama, Hitoshi Kusaba, Hiroaki Niiro, Koichi Akashi, Eishi Baba

Cancer science   109 ( 10 )   3032 - 3042   2018.10

PD-1+ TIM-3+ T cells in malignant ascites predict prognosis of gastrointestinal cancer. International journal

Michitaka Nakano, Mamoru Ito, Risa Tanaka, Kyoko Yamaguchi, Hiroshi Ariyama, Kenji Mitsugi, Tomoyasu Yoshihiro, Hirofumi Ohmura, Nobuhiro Tsuruta, Fumiyasu Hanamura, Kosuke Sagara, Yuta Okumura, Kenta Nio, Kenji Tsuchihashi, Shuji Arita, Hitoshi Kusaba, Koichi Akashi, Eishi Baba

Cancer science   109 ( 9 )   2986 - 2992   2018.9

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy. International journal

Hozumi Kumagai, Hitoshi Kusaba, Takeharu Yamanaka, Kenta Nio, Kyoko Inadomi, Kotoe Takayoshi, Mamoru Ito, Shingo Tamura, Akitaka Makiyama, Chinatsu Makiyama, Gen Hirano, Yoshihiro Shibata, Tsuyoshi Shirakawa, Kenji Mitsugi, Hiroshi Ariyama, Taito Esaki, Koichi Akashi, Eishi Baba

Medicine   97 ( 25 )   e11042   2018.6

Early tumor shrinkage indicates a favorable response to bevacizumab-based first-line chemotherapy for metastatic colorectal cancer. International journal

Mamoru Ito, Hitoshi Kusaba, Satomi Mukaide, Junji Kishimoto, Hozumi Shimokawa, Shingo Tamura, Akitaka Makiyama, Gen Hirano, Hisanobu Oda, Tsuyoshi Shirakawa, Masato Komoda, Keita Uchino, Risa Tanaka, Kenji Mitsugi, Taito Esaki, Shuji Arita, Hiroshi Ariyama, Koichi Akashi, Eishi Baba

Anti-cancer drugs   28 ( 10 )   1166 - 1173   2017.11

Pancreatic acinar cell carcinoma presenting with panniculitis, successfully treated with FOLFIRINOX: A case report. International journal

Tomoyasu Yoshihiro, Kenta Nio, Kenji Tsuchihashi, Hiroshi Ariyama, Kenichi Kohashi, Nobuhiro Tsuruta, Fumiyasu Hanamura, Kyoko Inadomi, Mamoru Ito, Kosuke Sagara, Yuta Okumura, Michitaka Nakano, Shuji Arita, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba

Molecular and clinical oncology   6 ( 6 )   866 - 870   2017.6

Programmed death-ligand 1 expression is associated with fibrosarcomatous transformation of dermatofibrosarcoma protuberans. International journal

Kenji Tsuchihashi, Hitoshi Kusaba, Yuichi Yamada, Yuta Okumura, Hozumi Shimokawa, Masato Komoda, Keita Uchino, Tomoyasu Yoshihiro, Nobuhiro Tsuruta, Fumiyasu Hanamura, Kyoko Inadomi, Mamoru Ito, Kosuke Sagara, Michitaka Nakano, Kenta Nio, Shuji Arita, Hiroshi Ariyama, Kenichi Kohashi, Ryuji Tominaga, Yoshinao Oda, Koichi Akashi, Eishi Baba

Molecular and clinical oncology   6 ( 5 )   665 - 668   2017.5