Updated on 2025/05/27

Information

 

写真a

 
Makoto Sumie
 
Organization
Kyushu University Hospital Anesthesiology & Critical Care Medicine Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス
Tel
0926425714
Profile
Homepage
  • https://www.kuaccm.med.kyushu-u.ac.jp/

    Department of anesthesiology and critical care medicine, Graduate school of medical science, Kyushu University　
    Department of anesthesiology and critical care medicin, Kyushu University hospital

Research Areas

  • Life Science / Anesthesiology

Degree

  • doctor's degree (Kyushu University, Japan) （ Kyushu University ）

Research History

  • Kyushu University Kyushu University Hospital Anesthesiology & Critical Care Medicine  Assistant Professor 

    2025.4 - Present

Research Interests・Research Keywords

  • Research theme： the Intensive Care Management of an acute decrease in level of consciousness in Critically ill Children

    Keyword： acute decrease in level of consciousness

    Research period： 2024.10 - Present

  • Research theme： Peripheral regional anesthesia in pediatric cardiac surgeries

    Keyword： Peripheral regional anesthesia

    Research period： 2024.10 - Present

  • Research theme： Severe Neonatal Morbidity of Infants Born to Mothers with Severe Maternal Morbidity

    Keyword： Severe Neonatal Morbidity

    Research period： 2024.4 - Present

  • Research theme： Prophylactic Interventions for Emergence Delirium in Pediatric

    Keyword： Delirium

    Research period： 2024.4 - Present

  • Research theme： Labour epidural analgesia and autism

    Keyword： Labour epidural analgesia

    Research period： 2023.4 - Present

  • Research theme： presynaptic glycine recepter

    Keyword： patch clamp

    Research period： 2016.4 - 2021.3

Awards

  • 優秀演題賞

    2025.6   日本麻酔科学会  

  • Travel award

    2024.5   SickKids Research training center  

Papers

  • Effects of dexamethasone on opioid consumption in pediatric tonsillectomy: a systematic review with meta-analysis

    Niimi N., Sumie M., Englesakis M., Yang A., Olsen J., Cheng R., Maynes J.T., Campisi P., Hayes J., Ng W.C.K., Aoyama K.

    Canadian Journal of Anesthesia   72 ( 1 )   106 - 118   2025.1   （ ISSN:0832610X ）

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    Language：English   Publisher：Canadian Journal of Anesthesia  

    Purpose: Tonsillectomy is one of the most common ambulatory procedures performed in children worldwide, with around 40,000 procedures performed in Canada every year. Although a prior systematic review indicated a clear role for dexamethasone as an analgesic adjunct, the quantity effect on opioid consumption is unknown. In the current systematic review with meta-analysis, we hypothesized that the use of dexamethasone reduces perioperative opioid consumption in pediatric tonsillectomy but does not increase rates of postoperative hemorrhage. Source: We systemically searched MEDLINE, Embase, Cochrane Databases, and Web of Science from inception to 23 April 2024. Randomized controlled trials that compared intravenous dexamethasone to placebo in pediatric tonsillectomy were included in the study. The primary outcome was perioperative opioid consumption, and the secondary outcomes included the incidence of postoperative hemorrhage. We used a random effects meta-analysis to compute the mean difference (MD) or risk ratio (RR) with 95% confidence interval (CI) for each outcome. Principal findings: Of the 1,329 studies identified in the search, we included 16 in the final analysis. Intravenous dexamethasone administration significantly reduced opioid consumption (MD, −0.11 mg·kg−1 oral morphine equivalent; 95% CI, −0.22 to −0.01) without increasing the incidence of readmission (RR, 0.69; 95% CI, 0.28 to 1.67) or reoperation due to postoperative hemorrhage (RR, 3.67; 95% CI, 0.79 to 17.1). Conclusions: Intravenous dexamethasone reduced perioperative opioid consumption in pediatric tonsillectomy without increasing the incidence of postoperative hemorrhage. Study registration: PROSPERO (CRD42023440949); first submitted 4 September 2023.

    DOI： 10.1007/s12630-024-02817-y

    Scopus

    PubMed

  • Effect of ondansetron and metoclopramide on postoperative nausea and vomiting in children undergoing tonsillectomy with or without adenoidectomy: a systematic review with meta-analysis

    Sumie M., Cheng S., Niimi N., Englesakis M., Yang A., Adam R.I., Pankiv E., Campisi P., Yamaura K., Hayes J., Aoyama K.

    Journal of Anesthesia   39 ( 3 )   345 - 354   2025   （ ISSN:09138668 ）

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    Language：English   Publisher：Journal of Anesthesia  

    Purpose: Postoperative nausea and/or vomiting (PONV/POV) following tonsillectomy occurs in up to 89% of children without antiemetic prophylaxis. Prior systematic reviews have not evaluated the relative efficacy of ondansetron and metoclopramide for PONV/POV, including their adverse effects. Methods: A systematic search was conducted of five databases from their inceptions to June 19, 2024. Inclusion criteria were randomized controlled trials (RCTs) comparing ondansetron and metoclopramide in pediatric patients undergoing tonsillectomy or adenotonsillectomy. The primary outcome was incidence of PONV/POV. Secondary outcomes were length of hospital stay (LOS) and adverse events including postoperative extrapyramidal reactions and delayed hospital readmissions. Pooled risk ratios (RRs) or mean differences (MDs) and 95% confidence intervals (CIs) were calculated using random-effects meta-analysis. Adjusted RRs were calculated using random-effects meta-regression. Risk of bias and certainty of evidence were assessed using Cochrane RoB 2 and GRADE, respectively. This study was registered in PROSPERO (42,024,499,702). Results: Five RCTs met all inclusion criteria, consisting of 861 patients. Ondansetron significantly reduced risk of PONV/POV by almost 50% (RR 0.48 95% CI 0.31–0.75, moderate quality evidence), compared to metoclopramide. Intraoperative opioid dose did not impact the RR. Ondansetron also significantly shortened LOS (MD − 26.92 min 95% CI − 47.24 min to − 6.60 min, moderate quality evidence). Only two RCTs addressed readmission rates or extrapyramidal reactions, although no events occurred in either study. Conclusion: Ondansetron is more effective than metoclopramide for PONV/POV prophylaxis, decreasing the risk of PONV/POV as well as LOS. Continued surveillance for adverse effects may be recommended when using either medication.

    DOI： 10.1007/s00540-025-03463-4

    Scopus

    PubMed

  • Prophylactic corticosteroids in neonatal cardiac surgeries using cardiopulmonary bypass: a systematic review and meta-analysis

    Kataoka K., Cheng S., Sumie M., Adam R.I., Niimi N., Cunningham J., Yang A., Ng W.C.K., Hayes J., Maynes J.T., Aoyama K.

    Journal of Anesthesia   2025   （ ISSN:09138668 ）

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    Language：English   Publisher：Journal of Anesthesia  

    Purpose: Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size and insufficient adrenal stress response. We hypothesized that corticosteroids reduce systemic inflammatory response and improve clinical outcomes in neonates undergoing cardiac surgery with CPB. Methods: A systematic search was conducted on six databases including MEDLINE from their inceptions to August 20, 2024. Inclusion criteria were randomized controlled trials (RCTs) comparing corticosteroids and placebo in neonates undergoing cardiac surgery with CPB. The primary outcomes were IL-6 and IL-10 serum levels. The secondary outcomes were postoperative clinical outcomes such as length of intensive care unit (ICU) stay, mortality, and incidence of acute kidney injury. Pooled risk ratios or mean differences (MDs) and 95% confidence intervals (CIs) were calculated using random-effects meta-analysis. Certainty of evidence were assessed following GRADE. This study was registered in PROSPERO (CRD42024548217). Results: Seven RCTs met all inclusion criteria, consisting of 316 patients. Administration of corticosteroids significantly decreased plasma IL-6 on POD1 (MD -64.21 pg/mL, 95% CI -118.26 to -10.16) and plasma IL-10 on POD1 (MD − 4.60 pg/mL, 95% CI − 8.07 to − 1.12). We confirmed corticosteroids administration did not improve clinical outcomes. Conclusion: Corticosteroids significantly reduced inflammatory cytokines on POD1. Routine prophylactic use of corticosteroids is not recommended even in neonatal cardiac surgery, however, because of high incidence of adrenal insufficiency in neonates after cardiac surgery with CPB, neonates with clinically suspected adrenal insufficiency could benefit from perioperative corticosteroids administration.

    DOI： 10.1007/s00540-025-03506-w

    Scopus

    PubMed

  • Multisystem inflammatory syndrome in children: an Umbrella review

    Shioji N., Sumie M., Englesakis M., Gilfoyle E., Maynes J.T., Aoyama K.

    Journal of Anesthesia   38 ( 3 )   309 - 320   2024.6   （ ISSN:09138668 ）

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    Language：English   Publisher：Journal of Anesthesia  

    We conducted an Umbrella review of eligible studies to evaluate what patient features have been investigated in the multisystem inflammatory syndrome in children (MIS-C) population, in order to guide future investigations. We comprehensively searched MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews from December 1, 2019 to the May 6, 2022. The time period was limited to cover the coronavirus disease-2019 (COVID-19) pandemic period. The protocol was registered in the PROSPERO registry (CRD42022340228). Eligible studies included (1) a study population of pediatric patients ≤21 years of age diagnosed with MIS-C; (2) an original Systematic review or Mata-analysis; (3) published 2020 afterward; and (4) was published in English. A total of 41 studies met inclusion criteria and underwent qualitative analysis. 28 studies reported outcome data of MIS-C. 22 studies selected clinical features of MIS-C, and 6 studies chose demographic data as a main topic. The mortality rate for children with MIS-C was 1.9% (interquartile range (IQR) 0.48), the ICU admission rate was 72.6% (IQR 8.3), and the extracorporeal membrane oxygenation rate was 4.7% (IQR 2.0). A meta-analysis of eligible studies found that cerebral natriuretic peptide in children with MIS-C was higher than that in children with COVID-19, and that the use of intravenous immunoglobulin (IVIG) in combination with glucocorticoids to treat MIS-C compared to IVIG alone was associated with lower treatment failure. In the future, for patients with MIS-C, studies focused on safety of surgery requiring general anesthesia, risk factors, treatment, and long-term outcomes are warranted.

    DOI： 10.1007/s00540-024-03323-7

    Scopus

    PubMed

  • Anesthetic management of pheochromocytoma and paraganglioma for patients with Fontan circulation: a case series

    Tanaka Y., Sumie M., Hashimoto T., Osawa S., Karashima Y., Kandabashi T., Yamaura K.

    JA Clinical Reports   9 ( 1 )   13   2023.12

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    Language：English   Publisher：JA Clinical Reports  

    Background: Anesthetic management of pheochromocytoma and paraganglioma with Fontan circulation is challenging for physicians, with attention to cardiovascular physiology. Case presentation: We performed anesthetic management for pheochromocytoma and paraganglioma in three patients with Fontan circulation. We maintained intraoperative central venous pressure at preoperative level under fluid infusion and administrating nitric oxide to decrease pulmonary arterial resistance. We administered noradrenaline or vasopressin if low blood pressure was present despite adequate central venous pressure. Although noradrenaline is prevalent for the case of noradrenaline-secreting tumor especially after resection, we could maintain blood pressure to administrate vasopressin without increasing central venous pressure. Retroperitoneal laparoscopic approach which could avoid intra-abdominal adhesions might be selectable as case 3. Conclusions: Sophisticated management is required for pheochromocytoma and paraganglioma with Fontan circulation.

    DOI： 10.1186/s40981-023-00605-z

    Scopus

    PubMed

  • Anesthetic management of hepatectomy for the patient with Fontan circulation: a case series

    Sumie M., Kameyama N., Akasaka T., Tanaka Y., Ando T., Kandabashi T., Karashima Y., Yamaura K.

    JA Clinical Reports   8 ( 1 )   94   2022.12

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    Language：English   Publisher：JA Clinical Reports  

    Background: Hepatectomy for patients with Fontan circulation consists of high central venous pressure and low pulmonary vascular resistance, and is challenging for physicians. Case presentation: We performed anesthetic management for hepatectomy in three patients with Fontan circulation. Massive bleeding and transfusion as well as careful management were needed. Open abdominal surgery had to be conducted instead of laparoscopic surgery for controlling bleeding in one case. We successfully performed general anesthesia using nitric oxide and inotropes while monitoring arterial pressure and central venous pressure in all the cases. Conclusions: To maintain Fontan circulation during hepatectomy, it is important to manage central venous pressure and ensure appropriate circulatory volume.

    DOI： 10.1186/s40981-022-00582-9

    Scopus

    PubMed

  • Anesthetic management of cesarean section in a patient with Takayasu’s arteritis: a case report

    Ando T., Sumie M., Sasaki S., Yoshimura M., Nobukuni K., Maki J., Matsushita K., Shirozu K., Higashi M., Yamaura K.

    JA Clinical Reports   8 ( 1 )   1   2022.12

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    Language：English   Publisher：JA Clinical Reports  

    Background: Takayasu’s arteritis (TA) is a chronic, progressive, inflammatory arteritis. We presented the case of cesarean section in a patient with TA. Case presentation: A 31-year-old pregnant woman with TA underwent a planned cesarean section at 34 weeks of pregnancy. She had stenosis of the cerebral and coronary arteries and heart failure due to aortic regurgitation. Spinal anesthesia was performed. In addition to standard monitoring, arterial blood pressure in the dorsalis pedis artery and regional cerebral tissue oxygen saturation were monitored. Intraoperative arterial blood pressure was maintained using continuous infusion of noradrenaline with a careful intermittent bolus infusion of phenylephrine. All the procedures were successfully performed without significant complications. Conclusions: In a pregnant woman with TA, severe stenosis of the cerebral and coronary arteries, and heart failure due to valvular heart disease, careful anesthetic management by selecting catecholamines and assessing the perfusion pressure for critical organs is important.

    DOI： 10.1186/s40981-021-00494-0

    Scopus

    PubMed

  • A pressure-resistant peripherally inserted central catheter is as useful as a central venous catheter for rapid fluid infusion: an in vitro study

    Maki J., Sumie M., Ide T., Nagamatsu M., Matsushita K., Shirozu K., Higashi M., Yamaura K.

    BMC Anesthesiology   22 ( 1 )   205   2022.12

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    Language：English   Publisher：BMC Anesthesiology  

    Background: Although peripherally inserted central catheters (PICCs) have been widely used, they have not been frequently used in anesthesia practice. The central venous pressure measured via PICCs are reportedly as accurate as that measured via central venous catheters (CVCs), but the findings concerning rapid infusion are unclear. This study examined whether or not pressure-resistant PICCs could be used for rapid fluid infusion. Methods: The in-line pressure was measured in similar-sized double-lumen catheters—4-Fr PICC (55, 45 and 35 cm) and 17-G CVC (20 and 13 cm)—at flow rates of saline decided using a roller pump system. We also examined the flow rate at an in-line pressure of 300 mmHg, which is the critical pressure at which hemolysis is considered to occur during blood transfusion. Results: The pressure-resistant PICCs obtained a high flow rate similar to that of CVCs, but the in-line pressures increased in proportion to the flow rate and catheter length. Flow rates at an intra-circuit pressure of 300 mmHg were not significantly different between the 45-cm PICC and 20-cm CVC. Conclusion: Pressure-resistant PICCs can be used for rapid fluid infusion.

    DOI： 10.1186/s12871-022-01738-x

    Scopus

    PubMed

  • Anesthetic management of cesarean section in a patient with Takayasu’s arteritis: a case report Reviewed International journal

    Ando T, Sumie M, Sasaki S, Yoshimura M, Nobukuni K, Maki J, Matsushita K, Shirozu K, Higashi M, Yamaura K.

    JA Clinical Reports   8 ( 1 )   2022.1

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    Language：English   Publishing type：Research paper (scientific journal)  

  • 3．Fontan 循環の非心臓手術

    住江 誠

    CIRCULATION CONTROL   43 ( 2 )   64 - 66   2022   （ ISSN:03891844 ）

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    Language：Japanese   Publisher：Japan Society of Circulation Control in Medicine  

    DOI： 10.11312/ccm.43.64

    CiNii Research

  • Predictors of failure of intersegmental line creation using bronchoscopic jet ventilation for thoracoscopic pulmonary segmentectomy. Reviewed International journal

    Ikeda M, Tanabe M, Fujimoto A, Matsuoka T, Sumie M, Yamaura K.

    JA Clinical Reports   6 ( 7 )   53   2021.7

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Association between ionized magnesium and postoperative shivering. Reviewed International journal

    Nakayama T, Umehara K, Shirozu K, Sumie M, Karashima Y, Higashi M, Yamaura K.

    Journal of Anesthesia   2021.5

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Antinociceptive effect of selective G protein-gated inwardly rectifying K+ channel agonist ML297 in the rat spinal cord. Reviewed International journal

    Masami Kimura, Hiroaki Shiokawa, Yuji Karashima, Makoto Sumie, Sumio Hoka, Ken Yamaura

    PLoS One   2020.9

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Resting pupil size is a predictor of hypotension after induction of general anesthesia Reviewed

    Ryohei Miyazaki, Makoto Sumie, Tadashi Kandabashi, Ken Yamaura

    Journal of Anesthesia   33 ( 5 )   594 - 599   2019.10

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    Language：English   Publishing type：Research paper (scientific journal)  

    Purpose: Arterial hypotension is a major adverse effect of general anesthesia. Patients with pre-existing autonomic dysfunction are at greater risk of hypotension. This study was performed to examine whether objective measurement of the pupillary light reflex is predictive of intraoperative hypotension. Methods: We studied 79 patients who underwent scheduled surgery under general anesthesia. Patients with severe cardiovascular disease or receiving antihypertensive agents were excluded. The light reflex was measured preoperatively using a portable infrared pupillometer, and the hemodynamic parameters were obtained from the anesthesia records. The patients were divided into two groups according to the development of hypotension: the hypotension and normotension groups. Multivariate logistic regression analysis was performed to determine the pupil parameters predictive of hypotension. Results: Patients in the hypotension group were older and had a greater pupil size or constriction velocity than those in the normotension group. Logistic regression analysis showed that post-induction hypotension was significantly associated with maximum pupil size or constriction velocity after adjustment for age and other clinical variables. Latency of the light reflex and the percent reduction of pupil size were not associated with hypotension. Age was a relatively strong predictor of hypotension; other confounding factors were not associated with hypotension. Conclusion: Measurement of maximum pupil size is useful to identify patients at risk for intraoperative hypotension. The influence of age must be considered during measurement of the pupil response.

    DOI： 10.1007/s00540-019-02672-y

  • Perioperative anesthetic management of intestinal pseudo-obstruction as a complication of pheochromocytoma Reviewed International journal

    Saki Okumura, Makoto Sumie, Yuji Karashima

    JA Clinical Reports   5   35   2019.5

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • オフポンプ冠動脈バイパス術中に冠動脈内に空気塞栓が生じ心停止を来たした一症例 Reviewed

    住江誠１　辛島裕士２　外須美夫１，２

    Cardiovascular Anesthesia   21 ( 1 )   105 - 108   2017.1

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.11478/jscva.2017-3-001

  • Direct effect of remifentanil and glycine contained in Ultiva® on nociceptive transmission in the spinal cord In vivo and slice patch clamp analyses Reviewed

    Makoto Sumie, Hiroaki Shiokawa, Ken Yamaura, Yuji Karashima, Sumio Hoka, Megumu Yoshimura

    PloS one   11 ( 1 )   2016.1

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    Language：English   Publishing type：Research paper (scientific journal)  

    Background: Ultiva® is commonly administered intravenously for analgesia during general anaesthesia and its main constituent remifentanil is an ultra-short-acting μ-opioid receptor agonist. Ultiva® is not approved for epidural or intrathecal use in clinical practice. Previous studies have reported that Ultiva® provokes opioid-induced hyperalgesia by interacting with spinal dorsal horn neurons. Ultiva® contains glycine, an inhibitory neurotransmitter but also an N-methyl-D-aspartate receptor co-activator. The presence of glycine in the formulation of Ultiva® potentially complicates its effects. We examined how Ultiva1 directly affects nociceptive transmission in the spinal cord. Methods: We made patch-clamp recordings from substantia gelatinosa (SG) neurons in the adult rat spinal dorsal horn in vivo and in spinal cord slices. We perfused Ultiva® onto the SG neurons and analysed its effects on the membrane potentials and synaptic responses activated by noxious mechanical stimuli. Results: Bath application of Ultiva® hyperpolarized membrane potentials under current-clamp conditions and produced an outward current under voltage-clamp conditions. A barrage of excitatory postsynaptic currents (EPSCs) evoked by the stimuli was suppressed by Ultiva®. Miniature EPSCs (mEPSCs) were depressed in frequency but not amplitude. Ultiva®-induced outward currents and suppression of mEPSCs were not inhibited by the μ-opioid receptor antagonist naloxone, but were inhibited by the glycine receptor antagonist strychnine. The Ultiva®-induced currents demonstrated a specific equilibrium potential similar to glycine. Conclusions: We found that intrathecal administration of Ultiva1 to SG neurons hyperpolarized membrane potentials and depressed presynaptic glutamate release predominantly through the activation of glycine receptors. No Ultiva1-induced excitatory effects were observed in SG neurons. Our results suggest different analgesic mechanisms of Ultiva® between intrathecal and intravenous administrations.

    DOI： 10.1371/journal.pone.0147339

  • 後頭骨-頸椎固定術後の抜管直後に上気道閉塞により換気困難に陥った1症例 Invited Reviewed

    松下 克之、森川 敬子、住江 誠、坂口 嘉郎、外 須美夫

    麻酔   62   168 - 171   2013.4

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Acute upper airway obstruction after extubation due to excessive anteflexion of the neck with occipitocervical fusion Reviewed

    Katsuyuki Matsushita, Keiko Morikawa, Makoto Sumie, Yoshiro Sakaguchi, Sumio Hoka

    Japanese Journal of Anesthesiology   62 ( 2 )   168 - 171   2013.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    A patient developed upper airway obstruction immediately after tracheal extubation due to excessive anteflexion of the neck with occipitocervical fusion. A 59-year-old woman who had undergone mastectomy 17 years previously was scheduled for occipitocervical fusion for C2 vertebral metastasis. Retroflexion of her neck was restricted. Nasal intubation under sedation was performed using bronchial fiberscopy under fentanyl and propofol anesthesia. Emergence from anesthesia was smooth, and extubation was performed. Immediately after extubation, the patient could not breathe, and manual mask ventilation was impossible. Re-intubation was performed 30 minutes after the extubation. Oral fiberscopy revealed pharyngeal obstruction, and laryngeal edema was not observed. Fixation of her neck in excessive anteflexion was suspected to have caused her dyspnea. Therefore, re-operation was performed, and she was transferred to the intensive care unit under anesthesia. One day postoperatively, extubation was performed successfully with no dyspnea. Fixation of the neck in excessive anteflexion is one of the causes of upper airway obstruction after occipitocervical fusion. We must carefully observe cervical X-ray films to locate the upper airway obstruction, and careful extubation using a tube exchanger is strongly recommended in this operation.

  • 子宮頸峡部妊婦に対する帝王切開の麻酔経験 Invited Reviewed

    木村 めぐみ、辛島 裕士、住江 誠、杉岡 章光、山田 洋平、藤田 恭之、神田橋 忠、外 須美夫

    麻酔   61   390 - 392   2012.4

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Inadvertent bleeding in an infant after inguinal hernioplasty leads to diagnosis of hemophilia B Reviewed

    Makoto Sumie, Kouhei Toyama, Tomoka Yokoo-Matsuoka, Ken Yamaura, Sumio Hoka, Keiko Morikawa, Chihiro Takamatsu

    Journal of Anesthesia   26 ( 2 )   299 - 300   2012.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-011-1290-5

  • Anesthetic management of a cervicoisthmic pregnancy patient undergoing cesarean section Reviewed

    Megumi Kimura, Yuji Karashima, Makoto Sumie, Norimitsu Sugioka, Youhei Yamada, Yasuyuki Fujita, Tadashi Kandabashi, Sumio Hoka

    Japanese Journal of Anesthesiology   61 ( 4 )   390 - 392   2012.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    Cervicoisthmic pregnancy is a rare obstetric condition that is potentially dangerous for the pregnant woman due to a high risk of abortion or preterm delivery. We here present a 29-year-old woman with cervicoisthmic pregnancy undergoing cesarean section at full term. Under combined epidural and spinal anesthesia, an infant was delivered alive, and the placenta was preserved without any forces to detach from the uterus. The surgery was completed without massive bleeding. The retained placenta was treated with methotrexate infusion into the uterus from the 6th day as well as uterine artery embolization at the 51th day postpartum. She subsequently required manual removal of the retained placenta under combined epidural and spinal anesthesia with only small bleeding. She was discharged from our hospital uneventfully. Meticulous preparation for massive bleeding and long-term treatment of the retained placenta are important in the perioperative management for cesarean section of a full term patient with cervicoisthmic pregnancy.

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Books

  • 鎮静・鎮痛の疑問Q＆A

    住江　誠、山浦　健（Role：Joint author）

    中外医学社  2021.5 

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    Language：Japanese   Book type：Scholarly book

Presentations

  • 自閉スペクトラム症発症に対する周産期非遺伝的リスク因子と硬膜外無痛分娩のリスクの比較 International coauthorship

    日本麻酔科学会第72回学術集会  2025.6  日本麻酔科学会

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    Event date： 2025.6

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • Fontan循環患者における非心臓手術 Invited

    日本麻酔科学会第72回学術集会  2025.6  日本麻酔科学会

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    Event date： 2025.6

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

    Venue：神戸   Country：Japan  

  • Fontan術後患者の分娩　～分娩様式・麻酔法の選択に着目して～

    藤田愛、住江誠、松下克之、水田幸恵、東みどり子、山浦　健

    日本心臓血管麻酔学会　第２６回学術大会  2021.10 

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    Event date： 2021.10

    Language：Japanese  

    Venue：金沢   Country：Japan  

  • フォンタン型循環の非心臓麻酔管理 Invited

    住江　誠

    日本小児麻酔学会　第２６回大会  2021.10 

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    Event date： 2021.10

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：仙台   Country：Japan  

  • 末梢挿入型中心静脈カテーテルは周術期に中心静脈カテーテルと同等に使用できるか？―輸液速度と回路内圧の関係の検討

    住江誠、牟田穂波、牧盾、白水和宏、東みどり子、山浦健

    日本麻酔科学会2021年度支部学術集会  2021.9 

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    Event date： 2021.9 - 2021.10

    Language：Japanese  

    Venue：宮崎   Country：Japan  

  • 非心臓手術における非弁膜症性心房細動患者の術後出血性合併症の危険因子: マッチドケースコントロールスタディ

    住江誠、谷口純彬、中島孝輔、梅原薫、東みどり子、山浦健

    日本麻酔科学会　第68回学術集会  2021.6 

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    Event date： 2021.6

    Language：Japanese  

    Venue：神戸   Country：Japan  

    【諸言】非弁膜症性心房細動（NVAF）患者に対する血栓塞栓症予防として、ワルファリンや直性作用型経口抗凝固薬（DOAC）が使用されている。周術期は抗血栓療法の休薬が行われるものの、手術侵襲、ヘパリンの使用による凝固能の変化は血栓塞栓症とともに出血性合併症の発症リスクも高くなる可能性がある。今回、非心臓手術において、NVAF患者の術後出血性合併症の危険因子について検討した。
    【対象と方法】対象は2013年4月から2020年3月に当施設で行われた麻酔科管理の予定非心臓手術でNVAFの患者1107例。治療介入が必要であった出血性合併症を発症した症例（出血性合併症発症群）と発症しなかった症例について、患者背景と転帰を後方視的に検討した。2群間の比較にはｔ検定、カイ二乗検定、フィッシャーの正確検定を使用した。
    【結果】対象患者のうち抗凝固療法を受けていたのは993例（89.7%）、ヘパリンに置換した症例は369例（33％）であった。出血性合併症発症群は62例（5.6％）であり、単変量解析で有意差を認めた年齢、APTT値、クレアチニンクリアランス（CCr）、総コレステロール値、心不全の既往、術式についてマッチさせcontrol群として2群を比較した。APTT値（42.7 sec vs. 36.9 sec、p＜0.01）、CCr（49.2　ｍl/min vs. 57.5 ml/min、p=0.01）、総コレステロール値（154 mg/dl vs. 173 mg/dl、p＜0.05）、心不全の既往（29 % vs. 8 %、p＜0.01）で有意差を認めた。
    【結論】NVAF患者の非心臓手術では、術前のAPTT値、CCr、総コレステロール値、心不全の既往が術後出血性合併症の危険因子であることが示唆された。

  • 非弁膜症性心房細動患者における術後出血性合併症の危険因子

    谷口　純彬、中島　孝輔、住江　誠、　梅原　薫、山浦　健

    日本麻酔科学会第67回学術集会  2020.6 

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    Event date： 2021.5

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • フォンタン術後遠隔期患者に対する肝腫瘍切除術の麻酔経験

    亀山　希、夏目　弓子、本田　志津子、宮原　梓、奥平　景子、住江　誠、神田橋　忠、山浦　健

    日本臨床麻酔学会第40回大会  2020.11 

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    Event date： 2020.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：島根   Country：Japan  

  • 成人先天性心疾患合併妊娠に対する無痛分娩の検討

    住江　誠、辛島　裕士、帯刀　英樹、塩瀬　明、山浦　健

    成人先天性心疾患学会  2020.1 

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    Event date： 2020.4

    Language：Japanese  

    Country：Japan  

  • 成人先天性心疾患に対するチーム医療　～麻酔科医の立場から～

    住江　誠

    日本小児循環器学会  2017.7 

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    Event date： 2020.4

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Country：Japan  

  • 周術期における非弁膜症性心房細動患者の血栓塞栓症発症の危険因子

    中島　孝輔、住江　誠、梅原　薫、秋吉　浩三郎、外　須美夫

    日本麻酔科学会  2018.5 

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    Event date： 2020.4

    Language：Japanese  

    Country：Japan  

  • Effect of selective GIRK channel agonist at spinal dorsal horn International conference

    Sumie Makoto

    BUK Pain Meeting  2019.8 

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    Event date： 2020.4

    Language：Japanese  

    Country：Japan  

  • 腕神経叢ブロックにおけるブロック肢の指尖温とperfusion indexの変化

    仁田畑　和紀、高森　信乃介、住江　誠、福留　拓哉、辛島　裕士、山浦　健

    九州麻酔科学会  2019.9 

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    Event date： 2020.4

    Language：Japanese  

    Country：Japan  

  • 開腹を余儀なくされたファロー四徴症根治術後の右心不全患者に対する腹腔鏡下肝部分切除術の麻酔経験

    住江　誠１）、帯刀　英樹2）、塩瀬　明2）、辛島　裕士3）

    日本成人先天性心疾患学会  2019.1 

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    Event date： 2019.5

    Language：Japanese  

    Country：Japan  

  • レミフェンタニルの副作用、急性耐性と痛覚過敏： 現状での理解と対応

    住江誠

    九州麻酔科学会第56回大会  2018.9 

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    Event date： 2019.5

    Language：Japanese  

    Country：Japan  

  • フォンタン術後患者の非開心術の麻酔管理

    住江誠

    日本心臓血管麻酔学会第23回学術集会  2018.9 

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    Event date： 2019.5

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Country：Japan  

  • 子どもに優しい手術　～術前・術中・術後管理で気を付けること～

    住江誠

    日本小児麻酔学会第24回大会  2018.10 

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    Event date： 2019.5

    Language：Japanese  

    Country：Japan  

  • Fontan術後遠隔期患者の非心臓手術に対する麻酔法の検討

    住江　誠１）、辛島　裕士２）、帯刀　英樹３）、塩瀬　明３）、外　須美夫１）２）

    日本成人先天性心疾患学会  2018.1 

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    Event date： 2018.1

    Language：Japanese  

    Country：Japan  

  • 乳幼児生体肝移植術における無肝期時間、グラフト重量、中心静脈圧が再灌流時バイタルサインに与える影響

    新井千晶１、住江誠２、辛島裕士３、外須美夫３

    日本小児麻酔学会  2017.10 

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    Event date： 2017.10

    Language：Japanese  

    Country：Japan  

  • 中鎖アシルCoA脱水素酵素欠損症の麻酔経験と周術期管理

    篠塚翔１　住江誠２　河野裕美１　宮崎良平２　神田橋忠３　外須美夫4

    日本麻酔科学会九州地方会  2017.9 

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    Event date： 2017.9

    Language：Japanese  

    Country：Japan  

  • 非弁膜症性心房細動に対する直接作用型経口抗凝固薬の周術期使用状況と合併症

    中野良太１　住江誠２　秋吉浩三郎３　外須美夫３

    日本麻酔科学会  2017.5 

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    Event date： 2017.5

    Language：Japanese  

    Country：Japan  

    【

  • 左肺の気胸に対する胸腔鏡下肺瘻閉鎖術で高二酸化炭素血症を来たし麻酔管理に難渋した１症例

    吉村美穂, 住江 誠, 宮崎 良平, 本山 嘉正, 神田橋 忠, 外 須美夫

    日本麻酔科学会九州地方会  2016.9 

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    Event date： 2016.9

    Language：Japanese  

    Venue：佐賀市文化会館   Country：Japan  

  • フォンタン術後遠隔期患者に対する腹腔鏡下肝切除術の麻酔管理

    住江 誠, 田中 悠登, 赤坂 泰希, 亀山 希, 中山 昌子, 白水 和宏, 東 みどり子, 山浦 健

    日本成人先天性心疾患学会雑誌  2022.1  (一社)日本成人先天性心疾患学会

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    Language：Japanese  

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MISC

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Professional Memberships

  • 日本成人先天性心疾患学会

  • 日本心臓血管麻酔学会

  • 日本麻酔科学会

  • 日本小児麻酔学会

Academic Activities

  • Journal of anesthesia

    Role(s)： Peer review

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  • Japanese Journal of Medical Association

    Role(s)： Peer review

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Research Projects

  • シナプス前グリシン受容体の機能性の証明

    Grant number：18K16452  2018 - 2020

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Early-Career Scientists

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    Authorship：Principal investigator  Grant type：Scientific research funding

Educational Activities

  • 医学部4年生に対する侵襲医学講義
    医学部5年生に対するベットサイド実習
    医学部6年生に対するクリニカルクラークシップ担当
    初期研修医への臨床指導
    専攻医への臨床指導

Class subject

  • 侵襲医学講義

    2025.4 - Present  

  • 医学部６年生クリニカルクラークシップ

    2021.4 - 2022.3   Full year

  • 医学部５年生ベットサイド実習

    2021.4 - 2022.3   Full year

  • 医学部４年生侵襲医学講義

    2021.4 - 2021.9   First semester

  • 医学部４年生　侵襲医学講義

    2020.4 - 2021.3   Full year

  • 医学部５年生　ベットサイド実習

    2020.4 - 2021.3   Full year

  • 医学部６年生　クリニカルクラークシップ

    2020.4 - 2020.9   First semester

  • ベットサイド実習

    2019.12 - 2020.2   Winter quarter

  • ベットサイド実習

    2019.10 - 2019.12   Fall quarter

  • ベットサイド実習

    2019.6 - 2019.8   Summer quarter

  • クリニカルクラークシップ

    2019.4 - 2020.3   Full year

  • 侵襲医学講義

    2019.4 - 2019.9   First semester

  • ベットサイド実習

    2019.4 - 2019.6   Spring quarter

  • 医学部５年生ベットサイド実習

    2018.4 - 2019.3   Full year

  • 医学部4年生　侵襲医学講義

    2018.4 - 2019.3   Full year

  • 医学部６年生　クリニカルクラークシップ

    2018.4 - 2018.9   First semester

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Outline of Social Contribution and International Cooperation activities

  • Tracheal intubation training for paramedics
    Joint research collaborating with staff of The Hospital for Sick Children in Toronto

Social Activities

  • 救急救命士を対象とした気管挿管実習

    消防署  九州大学病院手術室  2019.11

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    Audience：General,　Scientific,　Company,　Civic organization,　Governmental agency

Travel Abroad

  • 2023.4 - 2025.3

    Staying countory name 1：Canada   Staying institution name 1：The Hospital for Sick Children

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Surgical Clinical Medicine / Anesthesiology and Resuscitation

Clinician qualification

  • Preceptor

    Japanese Society of Anesthesiologists（JSA）

  • Specialist

    日本心臓血管麻酔学会

Year of medical license acquisition

  • 2005

Notable Clinical Activities

  • 手術室管理業務 周術期外来業務 麻酔業務