Updated on 2024/07/28

Information

 

写真a

 
KAWAKUBO NAONORI
 
Organization
Faculty of Medical Sciences Department of Clinical Medicine Assistant Professor
School of Medicine Department of Medicine(Joint Appointment)
Title
Assistant Professor
Contact information
メールアドレス
Profile
As an assistant professor at the Graduate School of Medicine, Kyushu University, I am concurrently engaged in clinical, educational, and research activities aimed at advancing pediatric surgery in Japan. In my clinical practice, I perform surgical treatments for pediatric solid malignant tumors. In my research, I focus on innovative adoptive immunotherapy approaches for pediatric solid malignant tumors. Additionally, I contribute to education by teaching classes and providing clinical training in general pediatric surgery and pediatric cancer to students.

Degree

  • PhD

Research History

  • 平成19年 (2007) 4月1日  国家公務員共済組合連合会 浜の町病院 初期研修医 平成21年(2009)3月31日 国家公務員共済組合連合会 浜の町病院 初期研修修了 平成21年(2009)4月1日  九州大学小児外科レジデント 平成21年(2009)10月31日 防府消化器病センター医師 平成23年 (2011) 4月1日  北九州市立医療センター小児外科レジデント 平成24年 (2012) 4月1日 福岡市立こども病院小児外科 医師 平成25年 (2013) 4月1日 九州大学小児外科医員 平成27年 (2015) 10月1日  菊地病院医師(九州大学小児外科診療従事医兼務) 平成29年(2017)4月1日  九州大学小児外科 助教 平成29年 (2017) 10月1日  国立がん研究センター中央病院 医員 令和2年(2020)4月1日 九州大学小児外科 助教講師

    平成19年 (2007) 4月1日  国家公務員共済組合連合会 浜の町病院 初期研修医 平成21年(2009)3月31日 国家公務員共済組合連合会 浜の町病院 初期研修修了 平成21年(2009)4月1日  九州大学小児外科レジデント 平成21年(2009)10月31日 防府消化器病センター医師 平成23年 (2011) 4月1日  北九州市立医療センター小児外科レジデント 平成24年 (2012) 4月1日 福岡市立こども病院小児外科 医師 平成25年 (2013) 4月1日 九州大学小児外科医員 平成27年 (2015) 10月1日  菊地病院医師(九州大学小児外科診療従事医兼務) 平成29年(2017)4月1日  九州大学小児外科 助教 平成29年 (2017) 10月1日  国立がん研究センター中央病院 医員 令和2年(2020)4月1日 九州大学小児外科 助教講師

Research Interests・Research Keywords

  • Research theme:Development of novel immunotherapy to pediatric malignant tumor

    Keyword:pediatric malignant tumor

    Research period: 2020.4 - 2021.8

Papers

  • The Effectiveness of Deflux® Treatment for Vesicoureteral Reflux Following Pediatric Renal Transplantation: A Single-Institution Challenging Experience. Invited Reviewed International journal

    2024.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • A salvage technique using a fibrous sheath to avoid the loss of the central veins in cases of pediatric intestinal failure. Invited Reviewed International journal

    Kondo K, Nagata K, Jimbo T, Kono J, Kawakubo N, Obata S, Yoshimaru K, Miyoshi K, Esumi G, Matsuura T, Masumoto K, Tajiri T, Taguchi T.

    Pediatr Surg Int.   2024.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Effects of changes in skeletal muscle mass on the prognosis of pediatric malignant solid tumors. Invited Reviewed International journal

    Omori A, Kawakubo N(Correspondence), Takemoto J, Souzaki R, Obata S, Nagata K, Matsuura T, Tajiri T, Taguchi T.

    Pediatr Surg Int.   2024.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • The volume of intestinal decompression can predict the necessity of surgical intervention for adhesive small bowel obstruction. Invited Reviewed International journal

    Kono J, Yoshimaru K, Kondo T, Takahashi Y, Toriigahara Y, Fukuta A, Obata S, Kawakubo N, Nagata K, Matsuura T, Tajiri T.

    J Pediatr Surg.   2024.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • The advantages of duct-to-duct biliary reconstruction in pediatric living donor liver transplantation. Invited Reviewed International journal

    Toriigahara Y, Matsuura T, Yanagi Y, Yoshimaru K, Uchida Y, Kajihara K, Shirai T, Kawano Y, Kawakubo N, Nagata K, Tajiri T.

    Pediatr Surg Int.   2024.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Successful management of pyriform sinus cyst and fistula using endoscopic electrocauterization. Invited Reviewed International journal

    Kawakubo N, Obata S, Yoshimaru K, Miyoshi K, Izaki T, Tajiri T.

    Den Open   2022.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • The Utility of Core-Needle Tumor Biopsy for Pediatric Patients. Invited Reviewed International journal

    Kawakubo N, Takemoto J, Koga Y, Hino Y, Tamaki A, Kohashi K, Ono H, Oda Y, Ohga S, Tajiri T.

    Pediatrics International   2022.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Assessment of resectability of mediastinal germ cell tumor using preoperative Computed Tomography. Invited Reviewed International journal

    Kawakubo N, Okubo Y, Yotsukura M, Yoshida Y, Nakagawa K, Yonemori K, Watanabe H, Yatabe Y, Watanabe S.

    Journal of Surgical Research.   2022.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Surgical treatment for pneumothorax and tumor-bronchial fistula secondary to pulmonary metastasis of osteosarcoma in pediatric and adolescent patients Invited Reviewed International journal

    Naonori Kawakubo, Tomoro Hishiki, Ayumu Arakawa, Miho Nakajima, Tadashi Kumamoto, Kazuo Nakagawa, Akira Kawai, Chitose Ogawa

    Journal of pediatric hematology oncology   2022.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Endoscopic surgical approach for pediatric solid tumors that permits complete curability and exhibits cosmetic advantages. Invited Reviewed International journal

    Fukuta A, Kawakubo N, Sozaki, R., Takemoto, J., Obata S, Matsuura T.

    Journal of Laparoscopic and advanced surgical techniques.   2021.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 123 I metaiodobenzylguanidine (MIBG) uptake predicts early relapse of neuroblastoma using semi-quantitative SPECT/CT analysis. Annals of Nuclear Medicine. Invited Reviewed International journal

    Kitamura Y, Baba S, Isoda T, Maruoka Y, Sasaki M, Kamitani T, Koga Y, Kawakubo N, Matsuura T, Ishigami K.

    Annals of Nuclear Medicine   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants. Invited Reviewed International journal

    Arakawa A, Ichikawa H, Kubo T, Motoi N, Kumamoto T, Nakajima M, Yonemori K, Noguchi E, Sunami K, Shiraishi K, Kakishima H, Yoshida H, Hishiki T, Kawakubo N, Kuroda T, Kiyokawa T, Yamada K, Yanaihara N, Takahashi K, Okamoto A, Hirabayashi S, Hasegawa D, Manabe A, Ono K, Matsuoka M, Arai Y, Togashi Y, Shibata T, Nishikawa H, Aoki K, Yamamoto N, Kohno T, Ogawa C.

    New England Journal of Medicine   2021.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Surgical management of intertumor abscesses caused by fistulous communications with the intestine: rare complication in pediatric malignant tumor: 2 case reports. Invited Reviewed International journal

    Kawakubo N, Hishiki T, Shirakawa N, Arakawa A, Sugawara S, Sone M, Arai Y Ogawa C, Shimada K.

    International Journal of Surgery: Oncology   2020.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Defentive tumor resection after myeloablative option in the multimodal treatment of high-risk neuroblastoma: a single institution experience. Invited Reviewed International journal

    Hishiki T, Fujino A, Watanabe T, Tahara K, Ohno M, Yamada Y, Tomonaga K, Kutsukake M, Fujita T, Kawakubo N, Matsumoto K, Kiyotani C, Shioda Y, Miyazaki O, Fuji H, Yoshioka T, Kanamori Y.

    Journal of Pediatric Surgery   2019.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • The influence of sarcopenia on high risk neuroblastoma. Invited Reviewed International journal

    Kawakubo N, Kinoshita Y, Souzaki R, Koga Y, Oba U, Ohga S, Taguchi T

    Journal of Surgical Research   2019.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Navigation surgery using indocyanine green fluorescent imaging for hepatoblastoma patients. Invited Reviewed International journal

    Souzaki R, Kawakubo N, Matsuura T, Yoshimaru K, Koga Y, Takemoto J, Shibui Y, Kohashi K, Hayashida M, Oda Y, Ohga S, Taguchi T.

    Pediatric Surgery International   2019.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Natural antibody against neuroblastoma of TH-MYCN transgenic mice does not correlate with spontaneopus regression Invited Reviewed International journal

    Kawakubo N, Harada Y, Ishii M, Souzaki R, Kinoshita Y, Tajiri T, Taguchi T, Yonemitsu Y

    Biocnemical and Biophysical Research Communications   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Sequential actions of immune effector cells induced by viral activation of dendritic cells to eliminate murine neuroblastoma Invited Reviewed International journal

    Kawakubo N, Tanaka S, Kinoshita Y, Tajiri T, Yonemitsu Y, Taguchi T

    Journal of Pediatric Surgery   2018.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Preoperative surgical simulation of laparoscopic adrenalectomy for neuroblastoma using a three-dimensional printed model based on preoperative CT images. Invited Reviewed International journal

    Souzaki R, Kinoshita Y, Ieiri S, Kawakubo N, Obata S, Jimbo T, Koga Y, Hashizume M, Taguchi,T

    Journal of Pediatric Surgery   2015.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Using an indwelled test tube as a good "navigator" during enterostomy closure Invited Reviewed International journal

    Hirose R, Tojigamori M, Obata S, Kawakubo N.

    Surgery Today   2012.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

▼display all

Books

  • Tumors of the Head and Neck, Pediatric Surgical Oncology, 1st edition

    Naonori Kawakubo, Tomoaki Taguchi

    2022.5 

     More details

    Language:English  

MISC

  • がん診療における層別化医療の現状と今後の展望 小児固形がんにおける層別化医療の現状と今後の展望 Reviewed

    田尻達郎、川久保尚徳

    日本外科学会雑誌   2023.4

     More details

    Language:Japanese  

  • 診断困難な小児外科症例:早期診断へのポイントとヒント 鼠径部嚢胞性病変 Reviewed

    川久保尚徳、田尻達郎

    雑誌 小児外科   2022.11

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • がんに対するワクチン 神経芽細胞腫 Reviewed

    川久保尚徳 田尻達郎

    臨床と研究   2022.5

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 小児がんプロフェッショナル養成講座-基礎編 ゲノム医療の基礎 Reviewed

    川久保尚徳 菱木知郎 田尻達郎 田口智章

    小児外科   2020.5

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Research Projects

  • 神経芽腫根絶を目的とした自然退縮機序の解明と新規スクリーニングシステムの開発

    2024 - 2026

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • 小児難治悪性固形腫瘍根絶を目的としたNK細胞様CD3陰性細胞を用いた革新的養子免疫治療実現に向けたプロトコール作成研究

    2021

    国立研究開発法人日本医療研究開発機構

      More details

    Authorship:Principal investigator  Grant type:Contract research

  • 小児悪性固形腫瘍に対するNK細胞を用いた国産型新規養子免疫治療の開発

    Grant number:20K17599  2020 - 2021

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

Class subject

  • 受胎成長発達

    2021.4 - 2021.9   First semester

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Surgical Clinical Medicine / Pediatric Surgery

Clinician qualification

  • Specialist

    Japan Surgical Society(JSS)

  • Specialist

    The Japanese Society of Pediatric Surgeons(JSPS)

  • Specialist

    Japan Gastroenterological Endoscopy Society(JGES)

  • 小児がん認定外科医

    日本小児血液がん学会

Year of medical license acquisition

  • 2007

Notable Clinical Activities

  • 小児がん認定外科医として、小児悪性固形腫瘍の治療に参画している。