Updated on 2024/12/06

Information

 

写真a

 
GOTO KENICHI
 
Organization
Faculty of Medical Sciences Department of Health Sciences Professor
Kyushu University Hospital Department of Nephrology,Hypertension,and Strokology(Concurrent)
School of Medicine Department of Health Sciences(Concurrent)
Graduate School of Medical Sciences Department of Health Sciences(Concurrent)
Title
Professor
Profile
九州大学保健学科での教育・研究 九州大学病院での高血圧外来診療(併任講師)

Degree

  • PhD

Research History

  • 九州歯科大学 助教

Research Interests・Research Keywords

  • Research theme:Research on hypertension prediction based on big data

    Keyword:hypertension big data

    Research period: 2022.10

  • Research theme:Relationship of home blood pressure with target organ damage

    Keyword:home blood pressure, target organ damage

    Research period: 2016.4

  • Research theme:Assessment of cardiovascular risks for prevention of cardiovascular diseases

    Keyword:cardiovascular diseases, risk factors

    Research period: 2010.4

  • Research theme:Endothelial dysfunction in hypertension

    Keyword:Hypertension, Endothelium, Endothelium-Derived Mediators, ion channel

    Research period: 1998.4

Papers

  • Sleep-related breathing disorder in a Japanese occupational population and its association with exercise-induced blood pressure elevation Reviewed

    Minako Inoue, Satoko Sakata, Hisatomi Arima, Ikumi Yamato, Emi Oishi, Ai Ibaraki, Takanari Kitazono, Kenichi Goto

    Hypertension Research   2024.12

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    Authorship:Last author   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1038/s41440-024-02050-6

  • Impact of smoking status on incident hypertension in a Japanese occupational population Reviewed

    Ikumi Yamato, Yasuo Kansui, Kiyoshi Matsumura, Minako Inoue, Ai Ibaraki, Satoko Sakata, Hisatomi Arima, Kenichi Goto, Takanari Kitazono

    HYPERTENSION RESEARCH   2024.11

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41440-024-01996-x

  • Sleep-related breathing disorder in a Japanese occupational population and its association with hypertension-stratified analysis by obesity status

    Inoue, M; Sakata, S; Arima, H; Yamato, I; Oishi, E; Ibaraki, A; Goto, K; Kitazono, T

    HYPERTENSION RESEARCH   47 ( 6 )   1470 - 1478   2024.6   ISSN:0916-9636 eISSN:1348-4214

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    Language:English   Publisher:Hypertension Research  

    Sleep-related breathing disorder (SRBD) causes hypertension, and obesity has been highly associated with SRBD, which has become a serious health problem in young and middle-aged Japanese males. However, the relation between SRBD and hypertension considering the effects of obesity remains unknown. In this cross-sectional study, we examined the relationship between SRBD and hypertension, with consideration for the effects of obesity, in Japanese occupational population. Using 3% oxygen desaturation index (3%ODI) obtained by simplified polysomnography (PSG), participants were classified into low (0 ≤ 3%ODI < 5), medium (5 ≤ 3%ODI < 15), and high (15 ≤ 3%ODI) 3%ODI groups. We excluded employees who had not undergone medical examination with simplified PSG in the same year from 2012 to 2018. Logistic regression analysis was performed to calculate odds ratios for having hypertension according to 3%ODI levels. In total, 2532 employees were included. Among them, 25% and 4% were categorized into the medium and high 3%ODI groups, respectively. The odds ratio for hypertension increased significantly with higher 3%ODI levels after adjustment for age, sex, alcohol drinking status and smoking status (p for trend < 0.0001). However, further adjustment for obesity status (body mass index ≥ 25 kg/m2) attenuated the associations. When we performed the stratified analysis by obesity status, the odds ratio for hypertension increased significantly with higher 3%ODI only for non-obese individuals, with significant interaction (p for interaction = 0.014). Higher 3%ODI was significantly associated with higher prevalence of hypertension especially in non-obese participants, suggesting the importance of vigilance for the presence of SRBD even in non-obese individuals. (Figure presented.)

    DOI: 10.1038/s41440-024-01612-y

    Web of Science

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  • Medication adherence and associated factors in newly diagnosed hypertensive patients in Japan: the LIFE study

    Sagara, K; Goto, K; Maeda, M; Murata, F; Fukuda, H

    JOURNAL OF HYPERTENSION   42 ( 4 )   718 - 726   2024.4   ISSN:0263-6352 eISSN:1473-5598

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    Language:English   Publisher:Journal of Hypertension  

    Hypertension is the leading cardiovascular risk factor worldwide. However, in Japan, only 30% of patients have their blood pressure controlled under 140/90 mmHg, and nonadherence to antihypertensives is thought to be a reason for the poor control of hypertension. We therefore sought to assess the adherence to hypertension treatment and to evaluate factors influencing patients’ adherence in a large, representative sample of the Japanese population. To this end, we analyzed claims data from the LIFE Study database, which includes 112 506 Japanese adults with newly diagnosed hypertension. Medication adherence was measured for a year postdiagnosis using the proportion of days covered (PDC) method. Factors associated with adherence to antihypertensives were also assessed. Among the total 112 506 hypertensive patients, the nonadherence rate (PDC ≤ 80%) for antihypertensives during the first year after initiation of the treatment was 26.2%. Younger age [31 – 35 years: odds ratio (OR), 0.15; 95% confidence interval (95% CI), 0.12 – 0.19 compared with 71 – 74-year-old patients], male gender, monotherapy, and diuretics use [OR, 0.87; 95% CI, 0.82 – 0.91 compared with angiotensin II receptor blockers (ARBs)] were associated with poor adherence in the present study. Cancer comorbidity (OR, 0.84; 95% CI, 0.79 – 0.91 compared with no comorbidity), prescription at a hospital, and living in a medium-sized to regional city were also associated with poor adherence. Our present findings showing the current status of adherence to antihypertensive medications and its associated factors using claims data in Japan should help to improve adherence to antihypertensives and blood pressure control.

    DOI: 10.1097/HJH.0000000000003661

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  • Vascular smooth muscle TRPV4 channel: a promising therapeutic target for salt-induced hypertension?

    Goto, K

    HYPERTENSION RESEARCH   46 ( 10 )   2409 - 2411   2023.10   ISSN:0916-9636 eISSN:1348-4214

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    Language:English   Publisher:Hypertension Research  

    [Figure not available: see fulltext.]

    DOI: 10.1038/s41440-023-01405-9

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  • Triglyceride, an Independent Risk Factor for New-Onset Hypertension: A Perspective

    Goto, K

    ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS   23 ( 12 )   1483 - 1490   2023   ISSN:1871-5303 eISSN:2212-3873

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    Language:English   Publisher:Endocrine, Metabolic and Immune Disorders - Drug Targets  

    Hypertension is the most important risk factor for cardiovascular disease worldwide. Alt-hough the pathogenesis of hypertension is complex and multifactorial, obesity-related hypertension has become a major focus of attention because of the continued increase in the prevalence of overweight and obesity. Several mechanisms have been suggested to underlie obesity-related hypertension, including an increase in sympathetic nervous system activity, an upregulation of the renin-angiotensin-aldosterone system, alterations in adipose-derived cytokines, and an augmentation of insulin re-sistance. Emerging evidence from observational studies (including those using Mendelian randomization) suggests that the presence of high triglycerides, which is a common comorbidity in obesity, is an independent risk factor for new-onset hypertension. However, little is known about the mechanisms underlying triglyceride-associated hypertension. We summarize the existing clinical evidence that has demonstrated the adverse effect of triglycerides on blood pressure, and we then discuss possible underlying mechanisms based on the evidence from animal and human studies, with a particular focus on the roles of endothelial function, white blood cells, i.e., lymphocytes, and pulse rate.

    DOI: 10.2174/1871530323666230619104853

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  • Chloride Ions, Vascular Function and Hypertension

    Goto, K; Kitazono, T

    BIOMEDICINES   10 ( 9 )   2022.9   ISSN:2227-9059 eISSN:2227-9059

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    Language:English   Publisher:Biomedicines  

    Blood pressure is determined by cardiac output and systemic vascular resistance, and mediators that induce vasoconstriction will increase systemic vascular resistance and thus elevate blood pressure. While peripheral vascular resistance reflects a complex interaction of multiple factors, vascular ion channels and transporters play important roles in the regulation of vascular tone by modulating the membrane potential of vascular cells. In vascular smooth muscle cells, chloride ions (Cl−) are a type of anions accumulated by anion exchangers and the anion–proton cotransporter system, and efflux of Cl− through Cl− channels depolarizes the membrane and thereby triggers vasoconstriction. Among these Cl− regulatory pathways, emerging evidence suggests that upregulation of the Ca2+-activated Cl− channel TMEM16A in the vasculature contributes to the increased vascular contractility and elevated blood pressure in hypertension. A robust accumulation of intracellular Cl− in vascular smooth muscle cells through the increased activity of Na+–K+–2Cl− cotransporter 1 (NKCC1) during hypertension has also been reported. Thus, the enhanced activity of both TMEM16A and NKCC1 could act additively and sequentially to increase vascular contractility and hence blood pressure in hypertension. In this review, we discuss recent findings regarding the role of Cl− in the regulation of vascular tone and arterial blood pressure and its association with hypertension, with a particular focus on TMEM16A and NKCC1.

    DOI: 10.3390/biomedicines10092316

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  • The transient receptor potential vanilloid 4 channel and cardiovascular disease risk factors. Reviewed

    Kenichi Goto and Takanari Kitazono

    Frontiers in Physiology   12   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fphys.2021.728979

  • Relationship between casual serum triglyceride levels and the development of hypertension in Japanese Reviewed International journal

    Yusuke Tomita, Satoko Sakata, Hisatomi Arima, Ikumi Yamato, Ai Ibaraki, Toshio Ohtsubo, Kiyoshi Matsumura, Masayo Fukuhara, Kenichi Goto, Takanari Kitazono

    J Hypertens   39   677 - 682   2021.4

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    DOI: doi: 10.1097/HJH.0000000000002693.

  • The Association of Small Dense Low-Density Lipoprotein Cholesterol and Coronary Heart Disease in Subjects at High Cardiovascular Risk Reviewed International journal

    Mayu Higashioka, Satoko Sakata, Takanori Honda, Jun Hata, Mao Shibata, Daigo Yoshida, Kenichi Goto, Takanari Kitazono, Haruhiko Osawa, Toshiharu Ninomiya

    J Atheroscler Thromb.   28   79 - 89   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.55350

  • Endothelium-dependent hyperpolarization (EDH) in diet-induced obesity. Reviewed

    Kenichi Goto and Takanari Kitazono

    Endocrine and Metabolic Science   1   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.endmts.2020.100062

  • The relationship between masticatory performance and intakes of foods and nutrients in Japanese male workers: A cross-sectional study Invited Reviewed International journal

    Fuyoko Kawashima Bori, Masayo Fukuhara, Chihiro Masaki, Yuko Ohta, Ikuo Nakamichi, Satoko Sakata, Kenichi Goto, Shota Kataoka, Satoko Kakuta, Masanori Iwasaki, Toshihiro Ansai, Ryuji Hosokawa

    J Oral Rehabil   47   1142 - 1149   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/joor.13039.

  • Small Dense Low-Density Lipoprotein Cholesterol and the Risk of Coronary Heart Disease in a Japanese Community Reviewed International journal

    Mayu Higashioka, Satoko Sakata, Takanori Honda, Jun Hata, Daigo Yoshida, Yoichiro Hirakawa, Mao Shibata, Kenichi Goto, Takanari Kitazono, Haruhiko Osawa, Toshiharu Ninomiya

    J Atheroscler Thromb   27   669 - 682   2020.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.51961

  • Serum Uric Acid Levels and Cardiovascular Mortality in a General Japanese Population: The Hisayama Study Reviewed International journal

    Satoko Sakata, Jun Hata, Takanori Honda, Yoichiro Hirakawa, Emi Oishi, Mao Shibata, Daigo Yoshida, Kenichi Goto, Takanari Kitazono, Toshiharu Ninomiya

    Hypertens Res   43   560 - 568   2020.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41440-019-0390-8

  • Endothelium-Dependent Hyperpolarization (EDH) in Diabetes: Mechanistic Insights and Therapeutic Implications. Reviewed

    Kenichi Goto and Takanari Kitazono

    Int J Mol Sci.   20   2019.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms20153737

  • C-reactive protein and incident hypertension in a worksite population of Japanese men Invited Reviewed International journal

    Kansui Y, Matsumura K, Morinaga Y, Inoue M, Kiyohara K, Ohta Y, Goto K, Ohtsubo T, Ooboshi H, Kitazono T

    JOURNAL OF CLINICAL HYPERTENSION   21 ( 4 )   524 - 532   2019.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jch.13510

  • Impact of obstructive sleep apnea on long-term blood pressure variability in Japanese men: a cross-sectional study of a work-site population Invited Reviewed International journal

    Kansui Y, Matsumura K, Morinaga Y, Inoue M, Sakata S, Oishi E, Goto K, Ohtsubo T, Ooboshi H, Kitazono T

    HYPERTENSION RESEARCH   41 ( 11 )   957 - 964   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41440-018-0096-3

  • Impact of serum uric acid on incident hypertension in a worksite population of japanese men. Invited Reviewed International journal

    Kansui Y, Matsumura K, Morinaga Y, Inoue M, Kiyohara K, Ohta Y, Goto K, Ohtsubo T, Ooboshi H, Kitazono T.

    J Hypertension.   2018.5

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  • Metyrapone-responsive ectopic ACTH-secreting pheochromocytoma with a vicious cycle via a glucocorticoid-driven positive-feedback mechanism. Invited Reviewed International journal

    Inoue M, Okamura K, Kitaoka C, Kinoshita F, Namitome R, Nakamura U, Shiota M, Goto K, Ohtsubo T, Matsumura K, Oda Y, Eto M, Kitazono T.

    Endocr J.   2018.5

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  • Endothelium-dependent hyperpolarization (EDH) in hypertension: The role of endothelial ion channels. Reviewed

    Kenichi Goto and Takanari Kitazono

    Int J Mol Sci.   19   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms19010315

  • Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men: A cross-sectional study in work-site group. Invited Reviewed International journal

    Morinaga Y, Matsumura K, Kansui Y, Sakata S, Goto K, Haga Y, Oishi E, Seki T, Ohtsubo T, Kitazono T.

    Clin Exp Hypertens.   2018.1

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  • Role of renin-angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients.Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men: A cross-sectional study in work-site group. Invited Reviewed International journal

    Inoue M, Matsumura K, Haga Y, Kansui Y, Goto K, Ohtsubo T, Kitazono T.

    Clin Exp Hypertens.   2017.12

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    DOI: doi: 10.1080/10641963.2017.1416119.

  • Angiotensin II receptor-neprilysin inhibitor sacubitril/valsartan improves endothelial dysfunction in spontaneously hypertensive rats. Invited Reviewed International journal

    Seki T, Goto K, Kansui Y, Ohtsubo T, Matsumura K, Kitazono T

    J. Am. Heart Assoc.   2017.10

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  • Disruption of xanthine oxidoreductase gene attenuates renal ischemia reperfusion injury in mice. Invited Reviewed International journal

    Haga Y, Ohtsubo T, Murakami N, Noguchi H, Kansui Y, Goto K, Matsumura K, Kitazono T.

    Life Sci.   2017.8

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  • Downregulation of endothelial transient receptor potential vanilloid type 4 channel and small-conductance of Ca2+-activated K+ channels underpins impaired endothelium-dependent hyperpolarization in hypertension Reviewed International journal

    Takunori Seki, Kenichi Goto, Kanako Kiyohara, Yasuo Kansui, Noboru Murakami, Yoshie Haga, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    Hypertension   ( 69 )   143 - 153   2017.1

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  • Trends in blood pressure control and medication use during 20 years in a hypertension clinic in Japan Invited Reviewed International journal

    CLINICAL AND EXPERIMENTAL HYPERTENSION   38 ( 3 )   299 - 304   2016.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3109/10641963.2015.1107086

  • Cognitive function and 10 year mortality in an 85 year-old community-dwelling population Reviewed International journal

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Hirok iFujii, Ritsuko Fujisawa, Kazuo Sonoki

    CLINICAL INTERVENTIONS IN AGING   9   691 - 699   2014.10

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  • Serum total cholesterol concentration and 10-year mortality in an 85-year-old population

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Hiroki Fujii, Ritsuko Fujisawa, Kazuo Sonoki

    CLINICAL INTERVENTIONS IN AGING   9   2014.2

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    DOI: 10.2147/CIA.S53754

  • Mice heterozygous for the xanthine oxidoreductase gene facilitate lipid accumulation in adipocytes

    Noboru Murakami, Toshio Ohtsubo, Yasuo Kansui, Kenichi Goto, Hideko Noguchi, Yoshie Haga, Yusaku Nakabeppu, Kiyoshi Matsumura, Takanari Kitazono

    Arteriosclerosis Thrombosis and Vascular Biology   34 ( 1 )   2014.1

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  • Body mass index and disease-specific mortality in an 80-year-old population at the 12-year follow-up

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Hiroki Fujii, Ritsuko Fujisawa, Kazuo Sonoki

    ARCHIVES OF GERONTOLOGY AND GERIATRICS   57 ( 1 )   2013.7

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    DOI: 10.1016/j.archger.2013.02.006

  • High level activities of daily living and disease-specific mortality during a 12-year follow-up of an octogenerarian population

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Hiroki Fujii, Ritsuko Fujisawa

    CLINICAL INTERVENTIONS IN AGING   8   721 - 728   2013.6

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  • Activities of daily living dependency and disease-specific mortality during 12-year follow-up in an 80-year-old population

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Kazuo Sonoki

    AGING CLINICAL AND EXPERIMENTAL RESEARCH   25 ( 2 )   2013.5

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    DOI: 10.1007/s40520-013-0029-6

  • Effects of the Superoxide Dismutase Mimetic Tempol on Impaired Endothelium-Dependent and Endothelium-Independent Relaxations in Type II Diabetic Rats

    Hideyuki Oniki, Kenichi Goto, Koji Fujii, Yasuo Kansui, Noboru Murakami, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    CLINICAL AND EXPERIMENTAL HYPERTENSION   35 ( 2 )   2013.2

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    DOI: 10.3109/10641963.2012.702829

  • Facilitation of sympathetic neurotransmission by phosphatidylinositol-4,5-bisphosphate-dependent regulation of KCNQ channels in rat mesenteric arteries

    Yasuo Kansui, Kenichi Goto, Toshio Ohtsubo, Noboru Murakami, Kunihiko Ichishima, Kiyoshi Matsumura, Takanari Kitazono

    HYPERTENSION RESEARCH   35 ( 9 )   2012.9

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    DOI: 10.1038/hr.2012.61

  • Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of dahl salt-sensitive hypertensive rats

    Kenichi Goto, Yasuo Kansui, Hideyuki Oniki, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    HYPERTENSION RESEARCH   35 ( 8 )   2012.8

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    DOI: 10.1038/hr.2012.36

  • Association of Body Mass Index with Glomerular Filtration Rate in Japanese: A Cross-Sectional Study in Work-Site Population

    Yasuo Kansui, Toshio Ohtsubo, Kenichi Goto, Hideyuki Oniki, Tomoko Yamasaki, Masayo Fukuhara, Yuko Ohta, Kiyoshi Matsumura

    CLINICAL AND EXPERIMENTAL HYPERTENSION   34 ( 2 )   2012.2

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    DOI: 10.3109/10641963.2011.601378

  • Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population

    Yutaka Takata, Toshihiro Ansai, Inho Soh, Shuji Awano, Yutaka Yoshitake, Yasuo Kimura, Ikuo Nakamichi, Kenichi Goto, Ritsuko Fujisawa, Kazuo Sonoki, Akihiro Yoshida, Kuniaki Toyoshima, Tatsuji Nishihara

    ARCHIVES OF GERONTOLOGY AND GERIATRICS   54 ( 1 )   2012.1

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    DOI: 10.1016/j.archger.2011.04.014

  • Association of Serum Uric Acid With Blood Pressure in Japanese Men - Cross-Sectional Study in Work-Site Group

    Yasuo Kansui, Toshio Ohtsubo, Kenichi Goto, Satoko Sakata, Kunihiko Ichishima, Masayo Fukuhara, Yuko Ohta, Kiyoshi Matsumura

    CIRCULATION JOURNAL   75 ( 12 )   2011.12

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    DOI: 10.1253/circj.CJ-11-0592

  • Non-linear relationship between hyperpolarisation and relaxation enables long distance propagation of vasodilation

    JOURNAL OF PHYSIOLOGY-LONDON   589   2607 - 2623   2011.5

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  • 歯学科3年次のPBLテュートリアルに対する学生の評価

    井上博雅, 粟野秀滋, 東泉, 後藤 健一, 辻澤利行, 大住伴子, 高田豊, 安細敏弘, 西原達次

    日本歯科医学教育学会雑誌   27   19 - 26   2011.4

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  • Role of Rho kinase and oxidative stress in cardiac fibrosis induced by aldosterone and salt in angiotensin type 1a receptor knockout mice

    Shuntaro Kagiyama, Kiyoshi Matsumura, Kenichi Goto, Toshio Ohtsubo, Mitsuo Iida

    REGULATORY PEPTIDES   160 ( 1-3 )   2010.2

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    DOI: 10.1016/j.regpep.2009.12.002

  • Improvement of blood Pressure control in a Hypertension Clinic in Japan: a 15-Year Follow-Up Study.

    Yuko Ohta, Kiyoshi Matsumura, Takuya Tsuchihashi, Toshio Ohtsubo, Hisatomi Arima, Yoshikazu Miwa, Kenichi Goto, Yusuke Ohya, Koji Fujii, Keiko Uezono, Isao Abe, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL HYPERTENSION   2009.11

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    DOI: 10.3109/10641960902927960

  • Cilostamide produces hyperpolarization associated with K(ATP) channel activation, but does not augment endothelium-derived hyperpolarization in rat mesenteric arteries

    Yasuo Kansui, Kenichi Goto, Koji Fujii, Hideyuki Oniki, Kiyoshi Matsumura, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY   36   729 - 733   2009.8

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  • Enalapril treatment alters the contribution of epoxyeicosatrienoic acids but not gap junctions to endothelium-derived hyperpolarizing factor activity in mesenteric arteries of spontaneously hypertensive rats

    Anthie Ellis*, Kenichi Goto*, Daniel J. Chaston, Therese D. Brackenbury, Kate R. Meaney, J. R. Falck, Richard J. H. Wojcikiewicz, Caryl E. Hill

    Journal of Pharmacology and Experimental Therapeutics   330   413 - 422   2009.8

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  • Depolarization evoked by acetylcholine in mesenteric arteries of hypertensive rats attenuates endothelium-dependent hyperpolarizing factor

    Kenichi Goto, Frank R Edwards, Caryl E Hill

    JOURNAL OF HYPERTENSION   25 ( 2 )   2007.2

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  • L/N型Ca拮抗薬シルニジピンの腎保護効果 —レニン・アンジオテンシン系抑制薬との併用に関する検討

    土橋卓也, 上野道雄, 冨永光裕, 梶岡智子, 尾中宇蘭, 後藤 健一, 大田祐子, 江藤仁香

    セラピューティック・リサーチ   27   1597 - 1603   2006.8

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  • Chronic fluvastatin treatment alters vascular contraction by inhibiting the Rho/Rho-kinase pathway

    Yasuo Kansui, Koji FUjii, Kenichi Goto, Hideyuki Oniki, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY   33 ( 8 )   2006.8

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  • Effects of angiotensin II receptor antagonist on impaired endothelium-dependent and endothelium-independent relaxations in type II diabetic rats

    Hideyuki Oniki, Koji Fujii, Yasuo Kansui, Kenichi Goto, Mitsuo Iida

    JOURNAL OF HYPERTENSION   24 ( 2 )   2006.2

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  • Antiproteinuric effect of an N-type calcium channel blocker, cilnidipine

    Takuya Tsuchihashi, Michio Ueno, Mitsuhiro Tominaga, Tomoko Kajioka, Uran Onaka, Kimika Eto, Kenichi Goto

    CLINICAL AND EXPERIMENTAL HYPERTENSION   27 ( 8 )   2005.10

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    DOI: 10.1080/10641960500298558

  • Attenuation of conducted vasodilatation in rat mesenteric arteries during hypertension: role of inwardly rectifying potassium channels

    Kenichi Goto, Nicole M Rummery, T. Hilton Grayson, Caryl E Hill

    JOURNAL OF PHYSIOLOGY-LONDON   561   215 - 231   2004.11

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    Language:English  

  • Changes in EDHF in hypertension and ageing: response to chronic treatment with rennin-angiotensin system inhibitors

    Kenichi Goto, Koji Fujii, Yasuo Kansui, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY   31   650 - 655   2004.9

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  • Angiotensin II receptor blockade corrects altered expression of gap junctions in vascular endothelial cells from hypertensive rats

    Yasuo Kansui, Koji Fujii, Keiichiro Nakamura, Kenichi Goto, Hideyuki Oniki, Isao Abe, Yosaburo Shibata, Mitsuo Iida

    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   287 ( 1 )   2004.7

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    DOI: 10.1152/ajpheart.00915.2003

  • Effects of fluvastatin on endothelium-derived hyperpolarizing factor- and nitric oxide-mediated relaxation in arteries of hypertensive rats

    Yasuo Kansui, Koji Fujii, Kenichi Goto, Hideyuki Oniki, Isao Abe, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY   31   354 - 359   2004.5

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  • Developmental changes in myoendothelial gap junction mediated vasodilator activity in the rat saphenous artery

    Shaun L. Sandow*, Kenichi Goto*, Nicole M. Rummery, Caryl E. Hill

    JOURNAL OF PHYSIOLOGY-LONDON   556 ( 3 )   2004.5

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    DOI: 10.1113/jphysiol.2003.058669

  • 早朝高血圧と降圧療法

    尾中宇蘭, 上野道雄, 梶岡智子, 後藤 健一, 江藤仁香, 冨永光裕, 土橋卓也, 藤井弘二

    セラピューティック・リサーチ   24   1857 - 1866   2003.9

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  • Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats

    Tsuneaki Sadanaga, Yusuke Ohya, Toshio Ohtsubo, Kenichi Goto, Koji Fujii, Isao Abe

    HYPERTENSION RESEARCH   25 ( 4 )   2002.7

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  • Critical role of gap junctions in endothelium-dependent hyperpolarization in rat mesenteric arteries

    Kenichi Goto, Koji FUjii, Yasuo Kansui, Isao Abe, Mitsuo Iida

    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY   29 ( 7 )   2002.7

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  • Angiotensin II receptor antagonist improves age-related endothelial dysfunction

    Yasuo Kansui, Koji Fujii, Kenichi Goto, Isao Abe, Mitsuo Iida

    JOURNAL OF HYPERTENSION   20 ( 3 )   2002.3

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  • 高血圧ラットにおける大動脈血管内皮細胞のK+チャネルの変化

    定永恒明, 大屋祐輔, 大坪 俊夫, 後藤 健一, 藤井弘二, 阿部功, 飯田三雄

    血圧   9   287 - 291   2002.3

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  • Bradykinin enhances sympathetic neurotransmission in rat blood vessels

    Yasuo Kansui, Koji Fujii, Kenichi Goto, Isao Abe, Mitsuo Iida

    HYPERTENSION   39 ( 1 )   2002.1

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  • N型Caチャネル阻害作用を有するシルニジピンの直接的な腎保護作用

    上野道雄, 梶岡智子, 佐内透, 赤崎卓, 平野直史, 後藤 健一, 冨永光裕, 大屋祐輔, 土橋卓也, 阿部功

    セラピューティック・リサーチ   22   1521 - 1524   2001.7

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  • Impaired beta-adrenergic hyperpolarization in arteries from prehypertensive spontaneously hypertensive rats

    Kenichi Goto, Koji Fujii, Isao Abe

    HYPERTENSION   37 ( 2 )   2001.2

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  • Renin-angiotensin system blockade improves endothelial dysfunction in hypertension

    Kenichi Goto, Koji Fujii, Uran Onaka, Isao Abe, Masatoshi Fujishima

    HYPERTENSION   36 ( 4 )   2000.10

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  • Angiotensin-converting enzyme inhibitor prevents age-related endothelial dysfunction

    Kenichi Goto, Koji Fujii, Uran Onaka, Isao Abe, Masatoshi Fujishima

    HYPERTENSION   36 ( 4 )   2000.10

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  • Effects of adrenomedullin and PAMP on membrane potential and neurotransmission

    Kenichi Goto, Koji Fujii, Uran Onaka, Isao Abe, Masatoshi Fujishima

    PEPTIDES   21 ( 2 )   2000.2

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  • Sympathetic control of arterial membrane potential by ATP-sensitive K+-channels

    Kenichi Goto, Koji Fujii, Isao Abe, Masatoshi Fujishima

    HYPERTENSION   35 ( 1 )   2000.1

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  • Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats

    Koji Fujii, Uran Onaka, Kenichi Goto, Isao Abe, Masatoshi Fujishima

    HYPERTENSION   34 ( 2 )   1999.8

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▼display all

Books

  • Polyphenols: A Promising Nutritional Strategy for the Prevention and Treatment of Hypertension In: Studies in Natural products Chemistry, ed. by ATTA-UR-RAHMAN, Vol.80

    Kenichi Goto( Role: Sole author)

    Elsevier  2024.3 

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    Responsible for pages:Volume 80, pages 15-54   Language:English   Book type:Scholarly book

  • Association of Disease-Specific Mortality with Physical Fitness Measurements and Nonparticipation in an 80-Year-Old Population. In: Geriatrics, ed. by Craig S. Atwood

    Yutaka Takata, Inho Soh, Shuji Awano, Yutaka Yoshitake, Yasuo Kimura, Ikuo Nakamichi, Sumio Akifusa, Kenichi Goto, Akihiro Yoshida, Ritsuko Fujisawa, Kazuo Sonoki( Role: Joint author)

    InTech  2012.1 

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    Responsible for pages:pp.59-82   Language:English   Book type:Scholarly book

  • Improvement of age-related impairment of endothelium-dependent hyperpolarization by rennin-angiotensin system blockade. In EDHF 2002 (Vanhoutte, P.M., ed.)

    Yasuo Kansui, Koji Fujii, Kenichi Goto, Mitsuo Iida( Role: Joint author)

    Taylor&Francis  2002.1 

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    Responsible for pages:pp.117-123   Language:English   Book type:Scholarly book

  • Effects of a converting enzyme inhibitor, an AT1 receptor antagonist and their combination on endothelial dysfunction in hypertension. In EDHF 2000 (Vanhoutte, P.M., ed.)

    Kenichi Goto, Koji Fujii, Isao Abe.( Role: Joint author)

    Taylor&Francis  2001.1 

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    Responsible for pages:Ch46   Language:English   Book type:Scholarly book

  • Inhibition of converting enzyme prevents the age-related decline in endothelium-dependent hyperpolarization. In EDHF 2000 (Vanhoutte, P.M., ed.)

    Koji Fujii, Kenichi Goto, Isao Abe( Role: Joint author)

    Taylor&Francis  2001.1 

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    Responsible for pages:Ch45   Language:English   Book type:Scholarly book

Presentations

  • 高血圧の予防と改善 ~生活習慣の修正~ Invited

    後藤健一

    令和6年度福岡県医師会生活習慣病健診等従事者講習会  2024.11  福岡県医師会

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    Event date: 2024.11 - 2025.3

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • EQ-5D-5Lを用いた主観的健康観と関連疾患の包括的分析:LIFE Study

    相良久美, 後藤健一, 前田恵, 村田典子, 能登真一, 福田治久

    第83回日本公衆衛生学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:札幌コンベンションセンター  

  • 高齢者における所得水準と健康行動との関連:LIFE Study

    明野由里奈, 後藤健一, 前田恵, 村田典子, 福田治久

    第83回日本公衆衛生学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese  

    Venue:札幌コンベンションセンター  

  • 治療中高血圧者において、室温は家庭血圧値に影響する:福岡高血圧コホート研究

    大森将, 松村潔, 大坪俊夫, 冨永光裕, 鍵山俊太郎, 川崎純也, 赤崎卓, 藤島八重, 阿部功, 二宮利治, 後藤健一, 土橋卓也, 北園孝成

    第46回日本高血圧学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡国際会議場   Country:Japan  

  • 日本人職域集団における睡眠関連呼吸障害と運動負荷後の血圧上昇との関連

    井上美奈子, 坂田智子, 有馬久冨, 大石絵美, 大和いくみ, 茨木愛, 後藤健一, 北園孝成

    第46回日本高血圧学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese  

    Venue:福岡国際会議場   Country:Japan  

  • 高血圧患者の受療状況と脳内出血発症との関連性についての検討:LIFE Study

    本田和也, 後藤健一, 福田治久

    第46回日本高血圧学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese  

    Venue:福岡国際会議場   Country:Japan  

  • Life’s Essential 8における健康行動と新規高血圧発症の関連性:LIFE Study

    相良空美, 後藤健一, 福田治久

    第46回日本高血圧学会総会  2024.10 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡国際会議場   Country:Japan  

  • 生活習慣病を予防して健康寿命をのばしましょう! Invited

    後藤健一

    西日本鉄道株式会社安全衛生大会  2024.2 

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    Event date: 2024.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 重症COVID-19サバイバーの退院180日以内死亡率と総医療費の比較検証:LIFE Study

    川端潤, 後藤健一, 前田恵, 村田典子, 福田治久

    第34回日本疫学会学術総会  2024.2 

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    Event date: 2024.1 - 2024.2

    Language:Japanese  

    Country:Japan  

  • 介護認定調査による高齢高血圧患者の服薬アドヒアランスとその関連要因の検討:LIFE Study

    相良空美, 後藤健一, 福田治久, 村田典子, 前田恵

    第82回日本公衆衛生学会総会  2023.11 

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    Event date: 2023.10 - 2023.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:つくば国際会議場   Country:Japan  

  • 1機会に測定した1回目と2回目の家庭血圧の変化に影響する因子の検討:福岡高血圧コホート(FHC)研究

    寒水康雄, 松村潔, 大森将, 坂田智子, 大坪俊夫, 冨永光裕, 鍵山俊太郎, 川崎純也, 赤崎卓, 藤島八重, 阿部功, 二宮利治, 後藤健一, 土橋卓也, 北園孝成

    第45回日本高血圧学会総会  2023.9 

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • 日本人職域集団における睡眠関連呼吸障害の実態と高血圧との関連ー肥満の有無による検討ー

    井上美奈子, 坂田智子, 有馬久冨, 大石絵美, 大和いくみ, 茨木愛, 後藤健一, 北園孝成

    第45回日本高血圧学会総会  2023.9 

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • 国保加入者における新規高血圧患者の服薬アドヒアランスの実態とその要因の分析:LIFE Study

    相良空美, 後藤健一, 福田治久

    第45回日本高血圧学会総会  2023.9 

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • 保健学部門における国際化推進への取り組み Invited

    後藤健一

    第6回 医系地区 国際化フォーラム  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 本邦の職域男性において、朝食抜きと喫煙の習慣が肥満発症に与える影響

    井上美奈子、後藤健一、北園孝成

    第15回福岡県医学会総会  2023.2 

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    Event date: 2023.2

    Language:Japanese  

    Country:Japan  

  • 健康経営と健康管理

    後藤健一

    西日本鉄道安全衛生大会  2023.2 

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    Event date: 2023.2

    Language:Japanese  

    Country:Japan  

  • 妊婦における食塩・カリウム摂取量が妊娠高血圧症候群の発症に及ぼす影響

    井上美奈子、土橋卓也、坂田智子、荒川仁香、冨永光裕、有馬久富、後藤健一、北園孝成

    第44回日本高血圧学会総会  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:国立京都国際会館   Country:Japan  

  • 日本人職域男性において、朝食抜き・喫煙の習慣が肥満発症に与える影響

    井上美奈子、坂田智子、有馬久富、大和いくみ、茨木愛、後藤健一、北園孝成

    第44回日本高血圧学会総会  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:国立京都国際会館   Country:Japan  

  • 高血圧予防は生活習慣の改善から Invited

    後藤健一

    第18回 九州大学保健学科公開講座  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • コロナ禍の健康管理 Invited

    後藤健一

    西日本鉄道安全衛生大会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Prevention and management of Hypertension Invited International conference

    Kenichi Goto

    Russia-Japan Medical Seminar  2022.2 

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    Event date: 2022.2

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Japan  

  • Prevention and Management of Hypertension in Japan in the time of COVID-19 Invited International conference

    Kenichi Goto

    International Conference "Challenges in NCDs management to achieve the SDGs in the COVID-19 era and beyond"  2022.1 

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    Event date: 2022.1

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Thailand  

  • 日本人職域集団における高血圧サブタイプごとの特性、3年後の血圧管理・治療状況について

    大和いくみ、坂田智子、富田祐亮、茨木愛、川本夕希、井上美奈子、大田祐子、有馬久富、後藤健一、北園孝成

    第43回日本高血圧学会総会  2021.10 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:沖縄   Country:Japan  

  • 日本人地域住民における高血圧管理状況の時代的推移:久山町研究

    大石絵美、坂田智子、秦淳、平川洋一郎、後藤健一、北園孝成、二宮利治

    第43回日本高血圧学会総会  2021.10 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:沖縄   Country:Japan  

  • 心血管予防を目指した高血圧治療 ―肥満に伴う高血圧の病態と治療― Invited

    後藤健一

    九州医療センター 地域医師のための生涯研修セミナー  2021.9 

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    Event date: 2021.9

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Japan  

  • Endothelium-dependent hyperpolarization (EDH) and endothelial dysfunction in hypertension: The role of endothelial ion channels Invited International conference

    Kenichi Goto

    Joint Meeting of The European Society for Clinical Hemorheology and Microcirculation, The International Society for Clinical Hemorheology, The International Society of Biorheology (ESCHM-IISCH-ISB 2021)  2021.7 

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    Event date: 2021.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  • 生体腎移植後に総腸骨動脈狭窄で難治性の高血圧を来した1症例

    大石 年訓, 大和 いくみ, 富田 佑亮, 坂田 智子, 後藤 健一, 北園 孝成

    第9回日本高血圧学会臨床高血圧フォーラム  2021.5 

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    Event date: 2021.5

    Language:Japanese  

    Venue:千里ライフサイエンスセンター   Country:Japan  

  • 日本人職域集団において随時血中トリグリセライド高値は高血圧発症を増加させた

    富田祐亮, 坂田智子, 大石年訓, 大和いくみ,, 茨木愛, 後藤健一, 大坪俊夫, 松村潔, 有馬久富, 福原正代, 北園孝成

    第42回日本高血圧学会総会  2019.6 

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    Event date: 2020.5 - 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • New Insights into RVO 網膜静脈閉塞症の真相を探る Hypertension and Guideline for the management of hypertension 2019 (JSH2019) Invited

    第73回日本臨床眼科学会  2019.10 

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    Event date: 2019.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:国立京都国際会館   Country:Japan  

  • 日本人職域集団におけるBMIと高血圧発症の関連について

    大和いくみ, 坂田智子, 大石年訓, 富田祐亮, 茨木愛, 後藤健一, 大坪俊夫, 松村潔, 有馬久富, 福原正代, 北園孝成

    第42回日本高血圧学会総会  2019.10 

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    Event date: 2019.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 喫煙習慣が高血圧発症に与える影響:職域集団男性での検討

    寒水康雄, 松村潔, 茨木愛, 富田祐亮, 大和いくみ, 清原嘉奈子, 大石絵美, 坂田智子, 大田祐子, 後藤健一, 有馬久富, 福原正代, 大星博明, 北園孝成

    第42回日本高血圧学会総会  2019.10 

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    Event date: 2019.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 高血圧再来患者の血圧管理状況と管理不良群の特徴についての検討

    大和いくみ, 坂田智子, 富田祐亮, 茨木愛, 後藤健一, 大坪俊夫, 松村潔, 北園孝成

    第8回臨床高血圧フォーラム  2019.5 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:久留米   Country:Japan  

  • 今日の血圧は昨日の血圧から予測できるか 朝28日間家庭血圧の時系列解析:福岡高血圧コホート研究.

    大森将, 坂田智子, 松村潔, 大坪俊夫, 冨永光裕, 後藤健, 阿部功, 𡈽橋卓, 北園孝成

    第8回臨床高血圧フォーラム  2019.5 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:久留米   Country:Japan  

  • 降圧治療者における家庭血圧と診察室血圧の差に関する検討 : 福岡高血圧コホート研究

    今津里奈, 荒川仁香, 冨永光裕, 坂田智子, 大森将, 松村潔, 後藤健一, 𡈽橋卓也, 北園孝成

    第8回臨床高血圧フォーラム  2019.5 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:久留米   Country:Japan  

  • 血清尿酸値が高血圧発症に及ぼす影響:職域男性での検討

    寒水康雄、松村潔、守永友希、井上美奈子、清原嘉奈子、大田祐子、後藤健一、大坪俊夫、大星博明、北園孝成

    第41回日本高血圧学会総会  2018.9 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 高感度CRPが高血圧発症に及ぼす影響:職域集団での検討

    寒水康雄、松村潔、守永友希、清原嘉奈子、坂田智子、富田祐亮、大田祐子, 後藤健一、福原正代、大坪俊夫、大星博明、北園孝成

    第7回臨床高血圧フォーラム  2018.5 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Downregulation of endothelial transient receptor potential vanilloid type 4 channel and small-conductance of Ca2+-activated K+ channels underpins impaired endothelium-dependent hyperpolarization in hypertension.

    Seki T, Goto K, Kiyohara K, Kansui Y, Murakami N, Haga Y, Ohtsubo T, Matsumura K, Kitazono T

    2017.10 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 長期的血圧変動に及ぼす睡眠時無呼吸症候群の影響:職域集団における検討

    寒水 康雄、松村 潔、守永 友希、井上 美奈子、坂田 智子、大石 絵美、後藤 健一、福原 正代、大坪 俊夫、大星 博明、北園 孝成

    第40回日本高血圧学会総会  2017.10 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:松山   Country:Japan  

  • 高血圧自然発症ラットの内皮機能障害に対するアンジオテンシン受容体ネプリライシン阻害薬(LCZ696)の効果 ーアンジオテンシン受容体拮抗薬との比較-

    関拓紀, 後藤 健一, 清原嘉奈子, 寒水康雄, 大坪 俊夫, 松村 潔, 北園 孝成

    第39回日本高血圧学会総会  2016.9 

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    Event date: 2016.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台   Country:Japan  

  • Downregulation of endothelial TRPV4 channel contributes to the reduced endothelium-dependent hyperpolarization in genetically hypertensive rats International conference

    Takunori Seki, Kenichi Goto, Kanako Kiyohara, Yasuo Kansui, Noboru Murakami, Yosie Haga, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    The 26th Scientific Meeting of the International Society of Hypertension  2016.9 

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    Event date: 2016.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Korea, Republic of  

  • レニン-アンジオテンシン-アルドステロン系が血圧変動性に及ぼす影響:ABPMを用いた検討

    芳賀祥江, 松村 潔, 瀧口知浩, 関 拓紀, 後藤 健一, 大坪 俊夫, 北園 孝成

    第5回臨床高血圧フォーラム  2016.5 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 高血圧ラットにおける内皮依存性過分極・弛緩反応の減弱にはTRPV4/SKCa 活性化経路の機能異常が関与している

    関拓紀, 後藤 健一, 清原嘉奈子, 寒水康雄, 村上 昇, 芳賀芳江, 大坪 俊夫, 松村 潔, 北園 孝成

    第51回高血圧関連疾患モデル学会  2015.10 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  • 腎虚血再灌流障害におけるxanthine oxidoreductaseの役割

    芳賀祥江, 大坪 俊夫, 関拓紀, 寒水康雄, 後藤 健一, 松村 潔, 北園 孝成

    第38回日本高血圧学会総会  2015.10 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:松山   Country:Japan  

  • 高血圧ラットにおける内皮依存性過分極・弛緩反応の減弱にはTRPV4/SKCa活性化経路の機能異常が関与している

    関拓紀, 後藤 健一, 清原 嘉奈子, 寒水 康雄, 村上 昇, 芳賀 祥江, 大坪 俊夫, 松村 潔, 北園 孝成

    第38回日本高血圧学会総会  2015.10 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:松山   Country:Japan  

  • 血管周囲脂肪組織はカリウムチャネルを介して血管平滑筋の収縮反応を抑制する

    寒水 康雄, 後藤 健一, 大坪 俊夫, 芳賀 祥江, 関拓紀, 大星 博明, 松村 潔, 北園 孝成

    第38回日本高血圧学会総会  2015.10 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:松山   Country:Japan  

  • 高血圧に伴うEDHF反応の障害へのTRPV4チャネルの関与

    関  拓紀, 後藤 健一, 大坪 俊夫, 松村 潔, 北園 孝成

    第21回 九州血液血管研究会  2014.11 

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    Event date: 2014.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡   Country:Japan  

  • 閉塞性睡眠時無呼吸症候群における血圧と心血管危険因子:職域集団における検討

    守永 友希, 松村 潔, 福原 正代, 寒水 康雄, 後藤 健一, 芳賀 祥江, 坂田 智子, 大坪 俊夫, 北園 孝成

    第37回日本高血圧学会総会  2014.10 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 高血圧の血管内皮機能障害にはTransient Receptor Potential Vanilloid 4 (TRPV4) チャネルの機能障害が関与する

    関 拓紀, 後藤 健一, 清原 嘉奈子, 寒水 康雄, 村上 昇, 芳賀 芳江, 大坪 俊夫, 松村 潔, 北園 孝成

    第37回日本高血圧学会総会  2014.10 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 血管周囲脂肪組織によるcGMP非依存性血管弛緩反応の機序の解明と肥満による障害

    寒水 康雄, 後藤 健一, 大坪 俊夫, 芳賀 祥江, 関 拓紀, 大星 博明, 松村 潔, 北園 孝成

    第37回日本高血圧学会総会  2014.10 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 腎臓の虚血再灌流障害におけるXanthine Oxidoreductaseと亜硝酸の役割

    芳賀 祥江, 大坪 俊夫, 関 拓紀, 寒水 康雄, 後藤 健一, 松村 潔, 北園 孝成

    第37回日本高血圧学会総会  2014.10 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • DISRUPTION OF XANTHINE OXIDOREDUCTASE GENE ATTENUATES RENAL ISCHEMIAREPERFUSION INJURY IN MICE International conference

    Yosie Haga, Toshio Ohtsubo, Noboru Murakami, Yasuo Kansui, Kenichi Goto, Takunori Seki, Kiyoshi Matsumura, Takanari Kitazono

    25th Meeting of the International Society of Hypertension  2014.6 

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    Event date: 2014.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Greece  

  • MODULATION OF NITRIC OXIDE-DEPENDENT RELAXATION OF RAT MESENTERIC ARTERY BY PERIVASCULAR ADIPOSE TISSUE International conference

    Yasuo Kansui, Kenichi Goto, Toshio Ohtsubo, Noboru Murakami, Yosie Haga, Takunori Seki, Hiroaki Ooboshi, Kiyoshi Matsumura, Takanari Kitazono

    25th Meeting of the International Society of Hypertension  2014.6 

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    Event date: 2014.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Greece  

  • DYSFUNCTION OF TRPV4-SKCA SIGNALING PATHWAY UNDERPINS IMPAIRED EDHF-MEDIATED RESPONSE IN MESENTERIC ARTERIES OF STROKEPRONE SPONTANEOUSLY HYPERTENSIVE RATS International conference

    Takunori Seki, Kenichi Goto, Kanako Kiyohara, Yasuo Kansui, Noboru Murakami, Yosie Haga, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    25th Meeting of the International Society of Hypertension  2014.6 

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    Event date: 2014.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Greece  

  • 脳卒中易発症性高血圧自然発症ラットの腸間膜動脈では、EDHF反応の障害にはTRPV4/SKCa活性化経路の機能異常が関与している

    関拓紀, 清原嘉奈子, 後藤 健一, 寒水康雄, 村上昇, 芳賀祥江, 大坪 俊夫, 北園 孝成

    第36回日本高血圧学会総会  2013.10 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • Xanthine Oxidoreductaseは、酸化ストレスを介して腎臓の虚血再灌流障害を引き起こす

    芳賀祥江, 村上昇, 大坪 俊夫, 寒水康雄, 後藤 健一, 松村 潔, 北園 孝成

    第36回日本高血圧学会総会  2013.10 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • 一酸化窒素によるcGMP非依存性血管弛緩反応:血管周囲脂肪組織における活性酸素種及びAMPKの役割

    寒水康雄, 後藤 健一, 大坪 俊夫, 村上昇, 清原嘉奈子, 芳賀祥江, 関拓紀, 大星博明, 松村 潔, 北園 孝成

    第36回日本高血圧学会総会  2013.10 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場   Country:Japan  

  • Facilitation of sympathetic neurotransmission by phosphatidylinositol-4,5-bisphosphate-dependent regulation of KCNQ channels in rat mesenteric arteries International conference

    Yasuo Kansui, Kenichi Goto, Toshio Ohtsubo, Noboru Murakami, Kunihiko Ichishima, Kiyoshi Matsumura, Takanari Kitazono

    24th Meeting of the International Society of Hypertension  2012.10 

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    Event date: 2012.9 - 2012.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Australia  

  • Reduced activity of SKCa channels accounts for the impaired EDHF-mediated relaxation in mesenteric arteries of stroke-prone spontaneously hypertensive rats International conference

    Kenichi Goto, Yasuo kansui, Kunihiko Ichishima, Toshio Ohtsubo, Kiyoshi Matsumura, Takanari Kitazono

    24th Meeting of the International Society of Hypertension  2012.10 

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    Event date: 2012.9 - 2012.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Australia  

  • Heterozygous deletion of xanthine oxidoreductase augments adipogenesis in white adipose tissue and induces obesity with insulin resistance International conference

    Noboru Murakami, Toshio Ohtsubo, Yasuo Kansui, Kenichi Goto, Kiyoshi Matsumura, Takanari Kitazono

    24th Meeting of the International Society of Hypertension  2012.10 

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    Event date: 2012.9 - 2012.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Australia  

  • 血管周囲脂肪組織はGuanylate Cyclaseを抑制して一酸化窒素に対する血管弛緩作用を減弱させる

    寒水康雄, 後藤 健一, 大坪 俊夫, 村上昇, 市島久仁彦, 松村 潔, 北園 孝成

    第35回日本高血圧学会総会  2012.9 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ウェスティンナゴヤキャッスル   Country:Japan  

  • 脳卒中易発症高血圧自然発症ラットの腸間膜動脈ではCa2+依存性K+チャネルの機能障害が内皮由来過分極因子を介した弛緩反応の障害に関与している

    後藤 健一, 寒水康雄, 市島久仁彦, 大坪 俊夫, 松村 潔, 北園 孝成

    第35回日本高血圧学会総会  2012.9 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ウェスティンナゴヤ   Country:Japan  

  • Xanthine oxidoreductase の発現低下は白色脂肪細胞における脂肪合成促進を来し、インスリン抵抗性を伴う肥満を惹起する:XOR遺伝子改変マウスを用いた検討

    村上昇, 大坪 俊夫, 寒水康雄, 後藤 健一, 松村 潔, 北園 孝成

    第35回日本高血圧学会総会  2012.9 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ウェスティンナゴヤキャッスル   Country:Japan  

  • 睡眠時無呼吸症候群がメタボリックシンドロームに及ぼす影響:職域集団での検討

    山田靖子, 松村 潔, 北園みゆき, 三好美智子, 大坪 俊夫, 後藤 健一, 福原 正代, 土井 康文, 寒水康雄, 北園 孝成

    第35回日本高血圧学会総会  2012.9 

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    Event date: 2012.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ウェスティンナゴヤキャッスル   Country:Japan  

  • ホスファチジルイノシトール二リン酸代謝はN型Ca2+チャネルを介して血管壁交感神経終末から神経伝達物質放出を促進する

    寒水康雄, 後藤 健一, 大坪 俊夫, 村上昇, 市島久仁彦, 松村 潔, 北園 孝成

    第34回日本高血圧学会総会  2011.10 

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    Event date: 2011.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:栃木県総合文化センター   Country:Japan  

  • 一酸化窒素合成阻害による血圧上昇におけるキサンチンオキシドリダクターゼ(XOR)の役割:XOR遺伝子改変マウスを用いた検討

    村上昇, 大坪 俊夫, 寒水康雄, 後藤 健一, 松村 潔, 北園 孝成

    第34回日本高血圧学会総会  2011.10 

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    Event date: 2011.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:栃木県総合文化センター   Country:Japan  

  • BMIの増加が糸球体濾過率低下に及ぼす影響 -職域男性における検討-

    寒水康雄, 松村 潔, 大坪 俊夫, 後藤 健一, 鬼木秀幸, 山崎朋子, 福原正代, 大田祐子

    第33回日本高血圧学会総会  2010.10 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡国際会議場   Country:Japan  

  • 高脂肪食負荷モデルマウスにおける腎障害・肝障害進展への尿酸産生酵素遺伝子欠損の影響

    大坪 俊夫, 松村 潔, 後藤 健一, 寒水康雄, 鬼木秀幸, 野口英子, 村上昇

    第33回日本高血圧学会総会  2010.10 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡国際会議場   Country:Japan  

  • Dahl食塩感受性高血圧ラットの腸間膜動脈ではBKCaチャネルの活性化により内皮由来過分極因子を介した弛緩反応が保持されており、障害されたNOの代償機構として内皮機能保護的に作用している

    後藤 健一, 松村 潔, 大坪 俊夫, 寒水康雄, 鬼木秀幸

    第33回日本高血圧学会総会  2010.10 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡国際会議場   Country:Japan  

  • Role of xanthine oxidoreductase in high fat diet-induced obesity mice International conference

    Toshio Ohtsubo, Kiyoshi Matsumura, Kenichi Goto, Hideko Noguchi, Hideyuki Oniki, Mitsuo Iida

    The 23rd Scientific Meeting of the International Society of Hypertension  2010.9 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Canada  

  • The association between serum uric acid and blood pressure in Japanese men International conference

    Toshio Ohtsubo, Kiyoshi Matsumura, Kenichi Goto, Hideyuki Oniki, Tomoko Yamasaki, Masayo Fukuhara, Yuko Ohta, Mitsuo Iida

    The 23rd Scientific Meeting of the International Society of Hypertension  2010.9 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Canada  

  • Association of body mass index with glomerular filtration rates in Japanese men International conference

    Kiyoshi Matsumura, Toshio Ohtsubo, Kenichi Goto, Tomoko Yamasaki, Masayo Fukuhara, Hideyuki Oniki, Yuko Ohta, Mitsuo Iida

    The 23rd Scientific Meeting of the International Society of Hypertension  2010.9 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Canada  

  • Effects of Na-K-2Cl cotransporter NKCCl on endothelial function in arteries of salt sensitive hypertensive rats International conference

    Kenichi Goto, Kiyoshi Matsumura, Toshio Ohtsubo, Mitsuo Iida

    The 23rd Scientific Meeting of the International Society of Hypertension  2010.9 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Canada  

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MISC

  • 血管収縮と抵抗

    後藤健一

    レシピプラス Vol.23 No1 降圧薬はこう扱う!   2024.1

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  • 高血圧緊急症と切迫症 Reviewed

    後藤健一

    臨床と研究   2023.1

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  • Alterations in Vascular Chloride Channels and Transporters

    Kenichi Goto, Takanari Kitazono

    Encyclopedia   2022.9

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  • 心血管予防を目指した高血圧治療 ―肥満に伴う高血圧の病態と治療― Reviewed

    後藤健一

    臨床と研究   2021.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 高血圧と血管内皮依存性過分極(EDH) Reviewed

    後藤健一

    福岡医学雑誌   2020.12

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    Repository Public URL: http://hdl.handle.net/2324/4371062

  • Rupture of a heavily calcified aortic arch in a patient with aortitis syndrome, advanced atherosclerosis, and renal ischemia: a dilemma between appropriate blood pressure control and maintenance of renal perfusion. Reviewed

    Shunsuke Yamada, Hideaki Oka, Kenichi Goto, Toshiaki Nakano, Takanari Kitazono

    CEN Case Rep   2020.10

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  • カルシウム拮抗薬

    後藤健一

    臨床と研究 2020, 97(1): 28-32.   2020.1

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  • 教室便り 病態機能内科学分野 Reviewed

    後藤健一

    学士鍋   2018.3

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    Language:Japanese  

  • 九州大学大学院医学研究院病態機能内科学(第二内科) Reviewed

    後藤健一

    日老医誌 2017;54:594―596   2017.10

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  • 多発性嚢胞を合併した原発性アルドステロン症の一例

    井上美奈子、松村潔、富田祐亮、入田英二、後藤健一、大坪俊夫、北園孝成

    血圧   2017.10

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    Language:Japanese  

  • 妊娠経過中に血圧が低下した腎血管性高血圧の一例

    井上美奈子、松村潔、鬼木秀幸、関拓紀、後藤健一、大坪俊夫、北園孝成

    血圧   2016.9

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    Language:Japanese  

  • 進行性の顕性蛋白尿が降圧治療により消失した原発性アルドステロン症の一例

    芳賀祥江、松村潔、瀧口知浩、関拓紀、後藤健一、大坪俊夫、北園孝成

    2016.7

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    Language:Japanese  

  • 自家腎移植が有効であった腎血管性高血圧の一例

    後藤 健一, 松村 潔, 大坪 俊夫, 小内 友紀子, 東間紘, 田邉一成, 飯田三雄

    血圧   2010.5

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    Language:Japanese  

  • 約20年間の降圧治療により良好に経過 した総頚動脈閉塞を伴う腎血管性高血圧の一例

    後藤 健一, 松村 潔, 山田淳平, 大坪 俊夫, 飯田三雄

    血圧   2009.4

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    Language:Japanese  

  • A case of Crohn’s disease associated with Takayasu’s arteritis and Henoch-Schönlein purpura

    2009.2

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    Language:English  

  • 血栓性微小血管障害による血小板減少を伴った加速型-悪性高血圧の1例

    後藤 健一, 松村 潔, 大坪 俊夫, 吉村映里, 山田淳平, 飯田三雄

    血圧   2008.2

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    Language:Japanese  

  • 両側副腎転移にて発見された起源不明の小腸肉腫の1症例 Reviewed

    後藤健一

    九州医療センター臨床研究センター便り   2001.10

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    Language:Japanese  

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Professional Memberships

  • 日本公衆衛生学会

  • 日本循環器病予防学会

  • 日本循環器学会

  • 日本高血圧学会

  • 日本内科学会

Committee Memberships

  • 日本高血圧学会   第46回日本高血圧学会演題選考委員   Domestic

    2024.10   

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    Committee type:Academic society

  • 日本高血圧学会   JHS2025執筆委員   Domestic

    2024.2 - 2025.8   

  • 日本高血圧学会   デジタル技術を活用した血圧管理に関する指針 指針作成委員   Domestic

    2023.1   

  • 日本高血圧学会   専門医資格・施設認定・カリキュラム小委員会委員   Domestic

    2022.11 - 2024.11   

  • 日本高血圧学会   専門医制度委員会委員   Domestic

    2022.11 - 2024.11   

  • 日本高血圧学会   診療・保険委員会委員   Domestic

    2018.12 - 2024.11   

  • 日本高血圧学会   日本高血圧学会高血圧治療ガイドライン2019 Systematic Review 委員   Domestic

    2017.4 - 2019.4   

  • Councilor  

    2011.10 - 2022.10   

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Academic Activities

  • 第46回日本高血圧学会総会 International Session International contribution

    Role(s): Panel moderator, session chair, etc.

    2024.10

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    Type:Academic society, research group, etc. 

  • 九州大学看護共創・実装研究拠点キックオフシンポジウム

    Role(s): Panel moderator, session chair, etc.

    ( 九州大学百年講堂 ) 2024.3

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    Type:Competition, symposium, etc. 

  • Hypertension Research Editorial Board International contribution

    2023.4 - Present

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    Type:Academic society, research group, etc. 

  • 第87回日本循環器学会学術集会

    Role(s): Panel moderator, session chair, etc.

    ( 福岡国際会議場 ) 2023.3

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    Type:Academic society, research group, etc. 

  • Screening of academic papers

    Role(s): Peer review

    2023

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:28

  • Frontiers in Physiology Editorial Board International contribution

    2022.8 - 2024.8

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    Type:Academic society, research group, etc. 

  • Screening of academic papers

    Role(s): Peer review

    2022

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:28

    Number of peer-reviewed articles in Japanese journals:1

  • コメンテーター

    第43回日本高血圧学会総会  ( 沖縄コンベンションセンター ) 2021.10

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    Type:Competition, symposium, etc. 

  • keynote Lecture演者 International contribution

    2021.7

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    Type:Competition, symposium, etc. 

  • Screening of academic papers

    Role(s): Peer review

    2021

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:17

  • Screening of academic papers

    Role(s): Peer review

    2020

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:14

  • シンポジウム演者 International contribution

    第73回日本臨床眼科学会  ( 国立京都国際会館、グランドプリンスホテル京都 ) 2019.10

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    Type:Competition, symposium, etc. 

  • Screening of academic papers

    Role(s): Peer review

    2019

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:7

  • Screening of academic papers

    Role(s): Peer review

    2018

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:7

  • Screening of academic papers

    Role(s): Peer review

    2017

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:3

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Research Projects

  • Development of the common risk approach technique for health promotion of the dialysis patient

    Grant number:24K13740  2024.4 - 2028.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

      More details

    Grant type:Scientific research funding

    CiNii Research

  • ビックデータを活用した降圧薬服薬アドヒアランスのエビデンス構築と保健指導への展開

    Grant number:24K14194  2024 - 2026

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    後藤 健一, 福田 治久

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    Authorship:Principal investigator  Grant type:Scientific research funding

    高血圧は脳心血管病の最大の危険因子であり、健康寿命の短縮を引き起こす。わが国における高血圧患者の管理状況は良好とはいえず、降圧薬服薬アドヒアランス不良が一因となっている。本研究では保健医療ビッグデータを活用し、わが国の高血圧患者の降圧薬服薬アドヒアランスの実態、降圧薬服薬アドヒアランス不良に関与する因子の解明、服薬アドヒアランスと脳心血管病発症リスクとの関連を分析し、日本人高血圧患者における降圧薬服薬アドヒアランスに関する質の高いエビデンスの創出を目指す。本研究の成果を保健指導に活用することで血圧管理不良者を減少させ、脳心血管病発症予防による健康寿命の延伸、および医療費の削減につなげたい。

    CiNii Research

  • Cardiovascular Risk reduction in Atrial Fibrillation Trial (CRAFT)

    Grant number:23K27862  2023.4 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant type:Scientific research funding

    CiNii Research

  • 炎症性腸疾患患者の病状と身体活動量の関連-生活習慣病に着目した患者・家族支援―

    Grant number:23K10372  2023.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    相星 香, 後藤 健一, 藤岡 審

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    Grant type:Scientific research funding

    近年、肥満が炎症性腸疾患の治療反応性に影響を与えること、運動が炎症性腸疾患の疾患活動性を抑制することが報告されており、身体活動量の増加は肥満を含む生活習慣病の改善を介して、炎症性腸疾患患者の生活の質や予後改善をもたらす可能性がある。
    運動を含む生活習慣の改善は患者だけでなく家族も含めて取り組め、看護が支援できる余地も大きいと考える。
    本研究では身体活動量が炎症性腸疾患患者の生活の質や疾患活動性に与える影響について生活習慣病との関連に着目して検討を行い、患者教育プログラムの開発を目指す。

    CiNii Research

  • 心房細動における脳心血管病予防のための降圧目標を解明する国際共同大規模臨床試験

    2023 - 2026

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 炎症性腸疾患患者の病状と身体活動量の関連-生活習慣病に着目した患者・家族支援―

    2023 - 2025

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 高血圧発症予防に向けた先制保健介入モデルの開発

    2022 - 2024

    科学研究費助成事業  日本医療研究開発機構(AMED)

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    Authorship:Coinvestigator(s)  Grant type:Competitive funding other than Grants-in-Aid for Scientific Research

  • 多職種連携による高血圧発症予防に関する研究

    Grant number:21K11023  2021 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    後藤 健一

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    Authorship:Principal investigator  Grant type:Scientific research funding

    わが国の高血圧患者の血圧管理は良好と言えず、とくに中年男性の高血圧有病率の増加が問題となっている。心血管病を予防するためには、高血圧患者の適切な血圧管理のみならず、高血圧を発症させないための予防的方策を確立する必要がある。本研究は、男性比率の高い職域集団を対象に、高血圧発症に関与する因子を明らかにし、適切な指導により高血圧発症予防につなげることを目的とした産業保健師と産業医の多職種連携による研究である。本研究により、わが国の中年男性の高血圧発症リスク因子が明らかとなり高血圧有病率低下につながるとともに、多職種連携コンピテンシーが醸成され、職域の健康管理の質の向上につながることが期待される。

    CiNii Research

  • 若年高血圧に関連する口腔内・腸内細菌を探索し予防と治療につなげる研究

    Grant number:19K10677  2019 - 2024

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    荒川 仁香, 有馬 久富, 後藤 健一, 冨永 光裕, 今津 里奈, 守永 友希, 井上 聡美

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

    まず、ケース・コホート研究の手法を用いて、高血圧患者と福岡県一般住民(非高血圧者)の腸内細菌プロファイルを比較し、高血圧に関連する腸内細菌を同定する。次に、高血圧患者を追跡し、減塩等の食事内容の変化や薬物治療がどのような腸内細菌叢の変化をもたらすかを畜尿による食塩摂取量評価と共に検討する。この結果、減塩を中心とした食事内容とそれに関連する腸内細菌プロファイルが明らかになりえる。そして、この結果をもとに腸内細菌を介した高血圧の新たな予防法や治療法の創出につなげるとともに、腸内細菌をもちいた降圧療法の個別化・最適化につながるものと期待される。

    CiNii Research

  • Cardiovascular Risk Reduction in Atrial Fibrillation Trial

    Grant number:19H03912  2019 - 2023

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    ARIMA HISATOMI

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

    In the present investigator-initiated, international, randomized controlled trial with long-term follow-up, high-risk patients with atrial fibrillation complicated by hypertension were randomly assigned to intensive blood pressure lowering group (target home systolic blood pressure <120 mm Hg) or standard treatment group (target home systolic blood pressure <135mm Hg). A total of 1343 patients with atrial fibrillation have been enrolled and 1016 have started randomized treatment. The mean values of home systolic blood pressure in the intensive blood pressure lowering group (124 mm Hg at 3 months, 122 mm Hg at 6 months, 123 mm Hg at 12 months, 123 mm Hg at 18 months, 122 mm Hg at 24 months and 118 mm Hg at 30 months) were 6-11 mm Hg lower than those in the standard treatment group. The Data Safety Monitoring Board did not point out any safety concerns.

    CiNii Research

  • EDHF産生機構が高血圧で障害される機序の解明

    Grant number:16K09645  2016 - 2018

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • Effect of combined AT1 receptor blocker and NEP inhibitor LCZ696 on endothelium-derived hyperpolarizing factor during hypertension

    2014.10 - 2017.9

    Research commissions

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    Authorship:Principal investigator  Grant type:Other funds from industry-academia collaboration

  • 85歳207名と80歳827名の10年間と15年間死亡・死因追跡コホート調査

    Grant number:24390472  2012 - 2016

    日本学術振興会  科学研究費助成事業  基盤研究(B)

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 高齢者における心臓機能と口腔の関係

    Grant number:23659989  2011 - 2014

    科学研究費助成事業  挑戦的萌芽研究

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    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 血管内皮機能保持における内皮由来過分極因子による代償機構の検討

    Grant number:21890233  2009 - 2010

    日本学術振興会  科学研究費助成事業  研究活動スタート支援

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    Authorship:Principal investigator  Grant type:Scientific research funding

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Class subject

  • 健康支援ケアシステム論Ⅱ

    2023.10 - 2024.3   Second semester

  • 臨床病態学

    2023.10 - 2024.3   Second semester

  • 医学総論Ⅰ

    2023.10 - 2023.12   Fall quarter

  • 終末期医療・ターミナルケア論

    2023.10 - 2023.12   Fall quarter

  • 国際プレゼンテーション(後藤教授)

    2023.4 - 2024.3   Full year

  • 看護学特別研究(後藤教授)

    2023.4 - 2024.3   Full year

  • 臨床看護学特論Ⅱ

    2023.4 - 2024.3   Full year

  • 臨床看護学特論Ⅰ

    2023.4 - 2024.3   Full year

  • 健康支援ケアシステム論Ⅰ

    2023.4 - 2023.9   First semester

  • ヘルスサイエンス論

    2023.4 - 2023.9   First semester

  • 国際社会とチーム医療

    2023.4 - 2023.9   First semester

  • 人体の構造と機能Ⅰ

    2023.4 - 2023.9   First semester

  • 公衆衛生学

    2023.4 - 2023.6   Spring quarter

  • 医学総論

    2022.12 - 2023.2   Winter quarter

  • 臨床病態学

    2022.10 - 2023.3   Second semester

  • 終末期医療・ターミナルケア論

    2022.10 - 2023.3   Second semester

  • 国際保健と医療

    2022.10 - 2023.3   Second semester

  • 3年生系統医学II(腎高血圧)

    2022.10 - 2023.3   Second semester

  • 国際プレゼンテーション(後藤教授)

    2022.4 - 2023.3   Full year

  • 臨床看護学特論Ⅱ

    2022.4 - 2023.3   Full year

  • 臨床看護学特論Ⅰ

    2022.4 - 2023.3   Full year

  • Health Science

    2022.4 - 2022.9   First semester

  • International Society and Multidisciplinary Care

    2022.4 - 2022.9   First semester

  • 健康支援ケアシステム論Ⅰ

    2022.4 - 2022.9   First semester

  • 人体の構造と機能Ⅰ

    2022.4 - 2022.9   First semester

  • 公衆衛生学

    2022.4 - 2022.6   Spring quarter

  • 医学総論

    2021.12 - 2022.2   Winter quarter

  • 臨床病態学

    2021.10 - 2022.3   Second semester

  • 終末期医療・ターミナルケア論

    2021.10 - 2022.3   Second semester

  • 国際保健と医療

    2021.10 - 2022.3   Second semester

  • 3年生系統医学II (腎高血圧)

    2021.10 - 2022.3   Second semester

  • 臨床看護学特論Ⅱ

    2021.4 - 2022.3   Full year

  • 臨床看護学特論Ⅰ

    2021.4 - 2022.3   Full year

  • ヘルスサイエンス論

    2021.4 - 2021.9   First semester

  • 国際社会とチーム医療

    2021.4 - 2021.9   First semester

  • 人体の構造と機能Ⅰ

    2021.4 - 2021.9   First semester

  • 公衆衛生学

    2021.4 - 2021.6   Spring quarter

  • 医学総論

    2020.12 - 2021.2   Winter quarter

  • 臨床病態学

    2020.10 - 2021.3   Second semester

  • 国際保健と医療

    2020.10 - 2021.3   Second semester

  • 国際社会とチーム医療

    2020.4 - 2020.9   First semester

  • 人体の構造と機能I

    2020.4 - 2020.9   First semester

  • 公衆衛生学

    2020.4 - 2020.6   Spring quarter

  • 3年生系統医学II(腎・高血圧

    2019.10 - 2020.3   Second semester

  • 3年生系統医学II(腎・高血圧)

    2018.10 - 2019.3   Second semester

  • 臨床医学群 腎・高血圧

    2017.10 - 2018.3   Second semester

  • 臨床医学群 腎・高血圧

    2016.10 - 2017.3   Second semester

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FD Participation

  • 2024.2   Role:Participation   Title:学生の海外留学における危機管理

    Organizer:Undergraduate school department

  • 2023.9   Role:Participation   Title:保健学部門における生成系AIの可能性と問題点について

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2022.9   Role:Planning   Title:保健学部門における国際化の推進とグローバル人材の育成

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2022.2   Role:Moderator   Title:With/After コロナにおける国際交流の在り方

    Organizer:Undergraduate school department

  • 2022.2   Role:Participation   Title:With/Afterコロナにおける国際交流の在り方

    Organizer:Undergraduate school department

  • 2021.2   Role:Participation   Title:カリキュラム改正に向けたAI教育導入の検討

    Organizer:Undergraduate school department

  • 2020.9   Role:Participation   Title:遠隔授業の現状を踏まえた今後の活用に向けて!

    Organizer:[Undergraduate school/graduate school/graduate faculty]

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Teaching Student Awards

  • 日本高血圧学会Young Investigator Promotion賞 最優秀賞

    Year and month of award:2024.10

    Classification of award-winning students:Doctoral student   Name of award-winning student:本田和也

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    Classification of the awarding organization:Doctoral student   Awarding organization:本田和也

  • 日本高血圧学会女性研究者奨励賞

    Year and month of award:2023.9

    Classification of award-winning students:Doctoral student   Name of award-winning student:相良久美

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    Classification of the awarding organization:Doctoral student   Awarding organization:相良久美

Other educational activity and Special note

  • 2024  Class Teacher 

  • 2023  Class Teacher 

  • 2022  Class Teacher 

  • 2021  Class Teacher 

  • 2018  Special Affairs 

  • 2016  Special Affairs 

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Social Activities

  • 産業医として健康講話を行った

    西日本鉄道株式会社  2024.2

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 産業医として健康講話を行った

    西日本鉄道株式会社  2023.2

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 高血圧予防は生活習慣の改善から

    第18回 九州大学保健学科公開講座  2022.10

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 産業医として健康講話を行った

    西日本鉄道株式会社  2022.3

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 産業医として健康講話を行った

    西鉄人事サービス株式会社  2020.12

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

  • 産業医として健康講話を行った

    西鉄人事サービス株式会社、ANA福岡空港株式会社  2020.6

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Lecture

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Media Coverage

  • とっても健康ランド 高血圧 TV or radio program

    KBC九州朝日放送  2023.8

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    とっても健康ランド 高血圧

Travel Abroad

  • 2002.10 - 2005.9

    Staying countory name 1:Australia   Staying institution name 1:The John Curtin School of Medical Research, Australian National University

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Internal Medicine / Cardiology

Clinician qualification

  • Certifying physician

    The Japanese Society of Internal Medicine(JSIM)

  • Specialist

    The Japanese Circulation Society(JCS)

  • Specialist

    The Japanese Society of Hypertension

  • Specialist

    The Japanese Society of Internal Medicine(JSIM)

Year of medical license acquisition

  • 1994

Notable Clinical Activities

  • 高血圧専門医として診療に従事している