Publisher：Trials  

Background: Periodontal disease during pregnancy has been associated with an increased risk of preterm birth (PTB) and low birth weight (LBW). However, most previous interventional studies have reported that scaling and root planing (SRP), a form of basic periodontal treatment, is insufficient to effectively prevent PTB and LBW. Recent systematic reviews and meta-analyses suggest that combining SRP with routine use of chlorhexidine gluconate (CHG) mouthwash may reduce the risk of these adverse birth outcomes by approximately half. This study will be among the first randomized controlled trials (RCTs) to evaluate the potential synergistic effects of this combined approach on improving birth outcomes. Methods: This multi-center, three-arm RCT will be conducted at two hospitals in Dhaka and Bogura, Bangladesh, between April 2025 and September 2026. A total of 480 pregnant women less than 20 weeks’ gestation attending antenatal checkups will be recruited. Participants diagnosed with periodontal disease will be randomly assigned to either an intervention group or a positive control group. Participants without periodontal disease will be assigned to a negative control group. The intervention consists of SRP combined with continued use of CHG mouthwash throughout pregnancy. The primary outcome will be the rate of PTB. Secondary outcomes include the birth weight of the newborn baby, maternal periodontal status, and oral health-related quality of life (OHRQoL). Effectiveness will be assessed by comparing outcomes across the study groups. Discussion: The oral health intervention is expected to improve both birth outcomes and maternal oral health. Demonstrating its effectiveness in a real-world setting may support the integration of oral health care into broader maternal, neonatal, and child health strategies, particularly in resource-limited settings. Trial registration: UMIN Clinical Trials Registry. UMIN000057519. Registered on April 4, 2025. https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000065719.

DOI： 10.1186/s13063-025-09355-y

Scopus

Publisher：東京医学社  

DOI： 10.24479/peri.0000002572

CiNii Research

Language：English   Publisher：Faculty of Arts and Science, Kyushu Unieversity  

The prevalence of obesity, hypertension (HTN), and type 2 diabetes mellitus (T2DM) is increasing worldwide, with significant public health implications, particularly in low- and middle-income regions. However, epidemiological data for remote rural districts in Sabah, Malaysia remains limited. This report aimed to assess the epidemiology of noncommunicable diseases (NCDs) such as obesity, HTN and T2DM among voluntary health checkup participants across selected districts in Sabah, Malaysia. A total of 1,247 adults aged 18 years or above underwent health checkups as part of Sabah state’s rural outreach activities, which included anthropometric measurements, blood pressure assessment, and blood glucose tests. Data analysis revealed that the proportion of obesity, HTN, and suspected T2DM was 21.7%, 40.3%, 28.1%, respectively. The percentage of participants who had both HTN and suspected T2DM was 13.7%. Older age was significantly associated with HTN and suspected T2DM. Higher rates of HTN were observed among males. Significantly higher odds ratios for having obesity, HTN, suspected T2DM, were found in rural districts including Beaufort, Tawau, and Lahad Datu districts, compared to the urban district of Kota Kinabalu. Participants in rural districts had a significantly higher likelihood of having two or more of these NCDs (comorbidity) than participants in the Kota Kinabalu district after controlling for sex and age. The findings highlight the urgent need for targeted community health interventions and policies addressing lifestyle modifications, with a focus on at-risk demographics in rural areas. This study provides a foundation for future research on NCDs in Sabah and emphasizes the importance of preventative measures in reducing the growing burden of obesity, HTN, and T2DM in Malaysia.

DOI： 10.15017/7339194

CiNii Research

DOI： 10.3233/SHTI240436

Publisher：Nutrients  

This study examined the association of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake during the second trimester with low birth weight (LBW) in pregnant Japanese women and was conducted in conjunction with the Japan Pregnancy Eating and Activity Cohort (J-PEACH) study. The study included 504 pregnant women from four Japanese sites. During the second trimester (14–27 weeks), the participants filled out a self-administered questionnaire assessing the frequency of DHA and EPA supplement intake in the past month, as well as a brief-type self-administered diet history questionnaire (BDHQ). The analysis involved data from two time points: responses to the BDHQ and infant data at birth. In total, 471 and 33 participants were classified into the normal birth weight and LBW groups, respectively. The participants were divided into high-, medium-, and low-intake groups based on their total dietary and EPA and DHA supplementary intakes. The Cochran–Armitage trend test was used to analyze the data; the prevalence of LBW was higher in the low-intake group (p = 0.04). There was no significant sex-based trend (p = 0.27 and p = 0.35). In Japanese women, low dietary and supplementary EPA and DHA intake until the second trimester were risk factors for LBW.

DOI： 10.3390/nu15224831

Scopus

Event date： 2017.3

Language：Japanese  

Country：Japan  

モンゴル助産師会と日本助産師会はICM Twinning Projectの一環で、モンゴルにおける妊婦肥満に関する共同研究を行った。2017年にモンゴルで初めての助産師と褥婦を対象とした全国的質問紙調査を行うために、2016年8月にWorkshop&Seminarに参加したモンゴル助産師会会員96名を対象にプレ質問紙調査を行った。モンゴル助産師の多くは、自国の妊婦肥満とそれに伴う大きな児の出産を認識していた。妊婦健診にてBMIを測定すると回答した助産師が半数のみであり、モンゴルにおける助産業務の検討を行う必要性が示唆された。

Event date： 2023.6

Language：Japanese  

Country：Japan  

Event date： 2021.6

Language：Japanese  

Venue：Online   Country：Indonesia  

Event date： 2019.6

Language：English  

The Japanese Midwives Association (JMA) and Mongolian Midwives Association (MMA) began a collaborative research (ICM Twinning Project) with active research starting in 2016, to clarify the Mongolian midwives’ & mothers’ recognition of obesity during pregnancy, and to consider methods for supporting their healthcare. In 2018 we conducted the 2nd National Consciousness Survey.
The proportion of mothers receiving nutritional guidance increased, with the pregnant women's obesity prevention pamphlet & the App used at high rates. However, the proportion of those unconcerned about weight gain has not changed, and it is necessary to examine specific midwifery support methods to promote maternal behavioral change in the future.

Event date： 2018.3

Language：Japanese  

Venue：横浜   Country：Japan  

モンゴル助産師の妊婦肥満に対する認識を明らかにするために、モンゴルで初めてのモンゴル助産師を対象とした全国的質問紙調査を行った。結果、モンゴル助産師の多くは自国の妊婦肥満とそれに伴う大きな児の出産を認識していた。また、ウランバートル市内の助産師と、他21県の助産師の認識の差を調査し、市内の方が日常的な運動不足により妊婦肥満が増加している可能性と、妊婦肥満に関する情報を受ける機会が多いため問題意識が高い可能性が示唆された。