Updated on 2024/12/11

Information

 

写真a

 
SANO TOMOMI
 
Organization
Faculty of Dental Science Department of Dental Science Assistant Professor
School of Dentistry Department of Dentistry(Concurrent)
Graduate School of Dental Science (Concurrent)
Graduate School of Dental Science Department of Dental Science(Concurrent)
Title
Assistant Professor
External link

Degree

  • Ph.D.

Research Interests・Research Keywords

  • Research theme:basic medical science

    Keyword:inflammation, miRNA, singaling

    Research period: 2011.4

Awards

  • 第96回日本薬理学会年会 優秀ポスター賞

    2022.12   日本薬理学会  

  • 保存学会奨励賞

    2018.6  

     More details

    歯周炎症が、全身性に増幅される機序を脂肪細胞-マクロファージ相互作用の観点から検討する目的で、共培養系を確立し炎症脂肪組織における高発現遺伝子を網羅的に解析した結果、マクロファージと脂肪細胞の共培養系において、成熟樹状細胞を誘引するCCL19の遺伝子発現が亢進することを見出し、CCL19とその受容体CCR7に着目した。遺伝性・食餌性肥満マウスでは、LPS注入後の血清CCL19濃度が増大し、CCR7欠損マウスでは、食餌誘導性肥満およびインスリン抵抗性の発症が抑制され、アディポネクチン経路および熱産生が亢進した。この現象はエピカテキン (EC) を添加した高脂肪食負荷マウスにおいても観察された。また、脂肪組織において炎症細胞浸潤はみられず、CD11c陽性細胞は野生型マウスでのみ観察された。すなわち、CCL19-CCR7経路が成熟樹状細胞の脂肪組織への遊走・浸潤に関与し、アディポネクチンシグナルおよび熱産生機能の抑制を介して肥満、インスリン抵抗性の発症に関与することを世界に先駆けて示したことに新規性がある。

  • 50th Perio Expo 2017 Poster Award

    2017.5   UNC  

     More details

    Epicatechin (EC) intake appears to be beneficial for the prevention of cardiovascular disorders, and it is well known that adipose tissue inflammation is one of the major risk factors for coronary heart diseases. Additionally, periodontal inflammation has been suggested to accelerate cardiovascular risk via enhancing adipose tissue inflammation. The purpose of the present study was to determine the in vitro and in vivo effects of EC on adipose tissue inflammation and obesity.
    DNA microarray analysis was performed to evaluate the effects of EC on gene expression in adipocytes co-cultured with endotoxin-stimulated macrophages. To determine the in vivo effects, C57BL/6 mice were fed either a high-fat diet (HFD) or HFD combined with EC, and metabolic changes were observed.
    EC suppressed the expression of many inflammatory genes in the adipocytes co-cultured with endotoxin-stimulated macrophages. Specifically, EC markedly suppressed chemokine (C-C motif) ligand 19 (CCL19) expression. The in vivo study indicated that mice fed the EC-supplemented HFD were protected from diet-induced obesity and insulin resistance. The expression levels of genes associated with inflammation in adipose tissue and in the liver were downregulated in this group of mice.
    EC exerts beneficial effects for the prevention of adipose tissue inflammation and insulin resistance. Since the mice deficient in the CCL19 receptor were protected from diet-induced obesity and insulin resistance, the beneficial effects of EC could be mediated, at least in part, by marked suppression of CCL19 expression. Thus, EC may also exert beneficial effects against periodontal inflammation-associated augmentation of cardiovascular risk.

Papers

  • Epicatechin suppresses the expression of C-C motif chemokine ligand 19 and ameliorates periodontitis. Reviewed

    Tomomi Sano, Yusuke Nakatsu, Meiqun Yuan, Rongzhi Li, Tomoichiro Asano, Atsushi Yasunaga, Takashi Kanematsu

    Journal of Functional Foods   122   106512   2024.10

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jff.2024.106512

  • Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure. Reviewed International journal

    Sano T, Sanada T, Sotomaru Y, Shinjo T, Iwashita M, Yamashita A, Fukuda T, Sanui T, Asano T, Kanematsu T, Nishimura F

    Nutr Metab   2019.7

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance. Reviewed International journal

    T Sano, S Nagayasu, S Suzuki, M Iwashita, A Yamashita, T Shinjo, T Sanui, A Kushiyama, T Kanematsu, T Asano, F Nishimura

    Nutr Metab Cardiovasc Dis.   2017.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling Reviewed International journal

    T sano, M Iwashita, S Nagayasu, A Yamashita, T Shinjo, A Hashikata, T Asano, A Kushiyama, N Ishimaru, Y Takahama, F Nishimura

    Obesity   23 ( 7 )   1460 - 1471   2015.7

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/oby.21127

  • Prolyl isomerase Pin1 in skeletal muscles contributes to systemic energy metabolism and exercise capacity through regulating SERCA activity Reviewed International journal

    Yusuke Nakatsu, Yasuka Matsunaga, Mikako Nakanishi, Takeshi Yamamotoya, Tomomi Sano, Takashi Kanematsu, Tomoichiro Asano

    Biochemical and Biophysical Research Communications   2024.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • miR-582-5p targets Skp1 and regulates NF-κB signaling-mediated inflammation. Reviewed International journal

    2023.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.abb.2022.109501.

  • miR-1260b inhibits periodontal bone loss by targeting ATF6β mediated regulation of ER stress Reviewed International journal

    2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis Reviewed International journal

    2022.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00592-022-01930-y

  • RANKL elevation activates the NIK/NF-κB pathway, inducing obesity in ovariectomized mice. Reviewed International journal

    254 ( 1 )   27 - 36   2022.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1530/JOE-21-0424

  • A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation Reviewed International journal

    Yamashita A, Sano T, Iwashita M, Nishimura F.

    Case Rep Dermatol Med.   2021.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2021/5548760

  • Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain. Reviewed International journal

    Hayashi M, Iwashita M, Nishimura Y, Shinjo T, Sano T, Yamashita A, Fukuda T, Sanui T, Asano T, Nishimura F.

    BMJ Open Diabetes Res Care.   9 ( 1 )   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1136/bmjdrc-2020-001871.

  • Expression of PRIP, a phosphatidylinositol 4,5-bisphosphate binding protein, attenuates PI3K/AKT signaling and suppresses tumor growth in a xenograft mouse model Reviewed International journal

    Maetani Y, Asano S, Mizokami A, Yamawaki Y, Sano T, Hirata M, Irifune M, Kanematsu T.

    Biochem Biophys Res Commun.   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Adipocyte-specific GPRC6A ablation promotes diet-induced obesity by inhibiting lipolysis. Reviewed International journal

    Mukai S, Mizokami A, Otani T, Sano T, Matsuda M, Chishaki S, Gao J, Kawakubo-Yasukochi T, Tang R, Kanematsu T, Takeuchi H, Jimi E, Hirata M.

    J Biol Chem.   2021.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • SPOCK1 induces adipose tissue maturation: New insights into the function of SPOCK1 in metabolism Reviewed International journal

    Rehab Alshargabi, Takanori Shinjo, Misaki Iwashita, Akiko Yamashita, Tomomi Sano, Yuki Nishimura, Masato Hayashi, Tatsuro Zeze, Takao Fukuda, Terukazu Sanui, Fusanori Nishimura

    Biochem Biophys Res Commun   2020.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbrc.2020.09.129

  • SPOCK1 Is a Novel Inducer of Epithelial to Mesenchymal Transition in Drug-Induced Gingival Overgrowth. Reviewed International journal

    Alshargabi R, Sano T, Yamashita A, Takano A, Sanada T, Iwashita M, Shinjo T, Fukuda T, Sanui T, Kishida S, Nishimura F.

    Sci Rep.   10 ( 1 )   9785   2020.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Anti-inflammatory effects of miRNA-146a induced in adipose and periodontal tissues Reviewed

    Taiki Sanada, Tomomi Sano, Yusuke Sotomaru, Rehab Alshargabi, Yosuke Yamawaki, Akiko Yamashita, Hiroaki Matsunaga, Misaki Iwashita, Takanori Shinjo, Takashi Kanematsu, Tomoichiro Asano, Fusanori Nishimura

    Biochemistry and Biophysics Reports   22   2020.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbrep.2020.100757

  • Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice. Invited Reviewed International journal

    Inoue MK, Matsunaga Y, Nakatsu Y, Yamamotoya T, Ueda K, Kushiyama A, Sakoda H, Fujishiro M, Ono H, Iwashita M, Sano T, Nishimura F, Morii K, Sasaki K, Masaki T, Asano T

    Diabetol Metab Synd   2019.7

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16. Reviewed International journal

    Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.

    Cell Rep.   2019.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles. Reviewed International journal

    2019.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • IL-17A synergistically enhances TNFα-induced IL-6 and CCL20 production in 3T3-L1 adipocytes. Reviewed International journal

    新城 尊徳, 岩下 未咲, 山下 明子, 佐野 朋美, 鶴田 満大, 松永 紘明, 讃井 彰一, 浅野 知一郎, 西村 英紀

    477 ( 2 )   241 - 246   2016.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-kappa B activation Invited Reviewed International journal

    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM   309 ( 3 )   E214 - E223   2015.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpendo.00553.2014

  • High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice Invited Reviewed International journal

    DIABETOLOGY & METABOLIC SYNDROME   7   2015.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s13098-015-0047-y

▼display all

Books

  • QUINT DIARY 2023

    ( Role: Joint author)

    2023.1 

     More details

    Language:Japanese   Book type:Scholarly book

  • 糖尿病合併症 管理・フォローアップ Ⅲ章「慢性合併症の管理」.

    佐野朋美、西村英紀( Role: Joint author)

    文光堂  2021.2 

     More details

    Language:Japanese  

  • 月刊糖尿病 6「歯周病と糖尿病」. Vol.11 No.4

    佐野朋美、西村英紀

    2019.10 

     More details

    Language:Japanese  

  • 患者さんのエイジングに備える・高齢者への歯周治療と口腔管理

    佐野 朋美他

    インターアクション株式会社  2018.3 

     More details

    Language:Japanese  

Presentations

  • Deficiency of PLCL in tumor-associated macrophages induces cancer malignancy by exacerbating the tumor microenvironment

    2023.12 

     More details

    Event date: 2023.12

    Language:English  

    Country:Japan  

  • Epicatechin exerts anti-inflammatory effect on periodontitis through suppression of CCL19 expression

    Tomomi Sano, Rongzhi Li, Fusanori Nishimura, Takashi Kanematsu

    2023.10 

     More details

    Event date: 2023.10 - 2023.11

    Language:English  

    Country:Japan  

  • RAW264.7においてmiR-15b-5pはCcr7を標的とし、M1マクロファージへの分化を抑制する

    佐野朋美、溝上顕子、兼松隆

    第76回日本薬理学会西南部会  2023.10 

     More details

    Event date: 2023.10

    Language:Japanese  

    Venue:沖縄   Country:Japan  

  • Study on the effect of PRIP on the polarization of M1/M2 macrophages

    Tomomi Sano, Malaz Elsheikh, Akiko Mizokami, Tamotsu Kiyoshima, Takashi Kanematsu

    2023.9 

     More details

    Event date: 2023.9

    Language:English  

    Country:Japan  

  • miR-582-5p, that targets Skp1 and suppresses NF-κB signaling-mediated inflammation, is down-regulated in periodontitis and obesity

    日本歯科保存学会2023年度春季大会 (第158回)  2023.6 

     More details

    Event date: 2023.6

    Language:English  

    Venue:松江   Country:Japan  

  • Regulatory mechanisms of tumor-associated macrophages in the tumor microenvironment

    Tomomi Sano, Du Haiyan, Akiko Mizokami, Takashi Kanematsu

    2022.9 

     More details

    Event date: 2023.6

    Language:English  

    Country:Japan  

  • Identification and characterization of a microRNA regulating adipocyte inflammation

    Malaz Elsheikh, Tomomi Sano, Akiko Mizokami, Takashi Kanematsu

    2022.9 

     More details

    Event date: 2023.6

    Language:English  

    Country:Japan  

  • MicroRNA targeting Skp1 regulates inflammatory response through NF-κB signaling pathway 

    第96回日本薬理学会年会  2022.12 

     More details

    Event date: 2023.6

    Language:English  

    Venue:横浜   Country:Japan  

  • 脂肪組織炎症でCCL19-CCR7経路が制御するmicroRNAの同定

    佐野朋美、Malaz Elsheikh、溝上顕子、兼松隆

    第63回歯科基礎医学会学術大会  2021.10 

     More details

    Event date: 2021.10

    Language:Japanese  

    Venue:Web   Country:Japan  

  • Identification of microRNAs involved in adipose tissue inflammation.

    Tomomi Sano

    2019 Taiwan Academy of Periodontology Annual Meeting and International Symposium  2019.11 

     More details

    Event date: 2019.11

    Language:English  

    Country:Taiwan, Province of China  

  • Anti-inflammatory effects of miRNA-146a induced in adipose and periodontal tissues. International conference

    Tomomi Sano

    The 59th General Session of Korean Academy of Periodontology  2019.11 

     More details

    Event date: 2019.11

    Language:English  

    Country:Korea, Republic of  

  • 脂肪・歯周組織で発現誘導されるmiRNA-146aによる抗炎症効果の検討

    真田大樹、佐野朋美

    第151回日本歯科保存学会2019年度秋季学術大会  2019.10 

     More details

    Event date: 2019.10

    Language:Japanese  

    Venue:福岡国際会議場(福岡市)   Country:Japan  

  • IDENTIFICATION OF MICRORNAS INVOLVED IN ADIPOSE TISSUE INFLAMMATION. International conference

    Sano Tomomi

    13th Asian Pacific Society of Periodontology Meeting  2019.9 

     More details

    Event date: 2019.9

    Language:English  

    Country:Malaysia  

  • Increased energy expenditure and resistance to obesity in CCR7KO mice. International conference

    Sano Tomomi

    The 96th General Session of the IADR  2018.7 

     More details

    Event date: 2019.6

    Language:English  

    Country:Japan  

  • The Role of Proteoglycans In Drug Induced Gingival Overgrowth (DIGO)

    Rehab Alshargabi, Tomomi Sano

    2018.11 

     More details

    Event date: 2019.6

    Language:English  

    Country:Japan  

  • 脂肪・歯周組織における抗炎症効果の検討

    眞田大樹、佐野朋美

    平成30年度 日本歯周病学会九州五大学・日本臨床歯周病学会九州支部・合同研修会  2018.11 

     More details

    Event date: 2019.6

    Language:Japanese  

    Country:Japan  

  • 脂肪・歯周組織で発現誘導されるmiRNAによる抗炎症効果の検討

    眞田大樹、佐野朋美

    第62回春季日本歯周病学会学術大会  2019.5 

     More details

    Event date: 2019.5

    Language:Japanese  

    Venue:神奈川県民ホール(横浜市)   Country:Japan  

  • CCR7欠損マウスにおける脂肪および歯周組織炎症抑制機序の考察

    佐野朋美

    第61回秋季日本歯周病学会学術大会  2018.10 

     More details

    Event date: 2018.10

    Language:Japanese  

    Country:Japan  

  • Influences of energy metabolism via CCL19-CCR7 pathway on diet-induced obesity and insulin resistance. International conference

    The 12th meeting of the Asian Pacific Society of Periodontology.  2017.9 

     More details

    Event date: 2018.6

    Language:English  

    Country:Korea, Republic of  

  • Study on the mechanism of increased energy expenditure of CCR7 deficient mouse. International conference

    The 65th Annual Meeting of Japanese Association for Dental Research.  2017.11 

     More details

    Event date: 2018.6

    Language:English  

    Country:Japan  

  • エピカテキンは歯肉線維芽細胞─マクロファージ相互作用による過剰な炎症反応を抑制する

    眞田 大樹、佐野 朋美

    日本歯周病学会60周年記念京都大会  2017.12 

     More details

    Event date: 2018.6

    Language:Japanese  

    Country:Japan  

  • 炎症脂肪/歯周組織における抗炎症分子の探索研究

    眞田 大樹、佐野 朋美

    日本歯科保存学会2018年度春季学術大会  2018.6 

     More details

    Event date: 2018.6

    Language:Japanese  

    Country:Japan  

  • CCR7欠損マウスにおけるエネルギー消費亢進機序についての検討

    佐野 朋美

    日本歯科保存学会2017年度秋季学術大会  2017.10 

     More details

    Event date: 2017.10 - 2018.6

    Language:Japanese  

    Country:Japan  

  • CCL19-CCR7経路を介したエネルギー代謝機構が肥満およびインスリン抵抗性に及ぼす影響の機序に関する検討

    佐野 朋美

    日本歯科保存学会2017年度春季学術大会  2017.6 

     More details

    Event date: 2017.6

    Language:Japanese  

    Venue:青森   Country:Japan  

  • エネルギー代謝機構がCCL19-CCR7経路を介した肥満およびインスリン抵抗性に及ぼす影響に関する検討

    佐野 朋美

    第60回日本糖尿病学会年次学術集会  2017.5 

     More details

    Event date: 2017.5

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  • Epicatechin Down-regulates Adipose Tissue CCL19 Expression, Thereby Ameliorates Diet-induced Obesity and Insulin Resistance International conference

    UNC Perio 2017 EXPO  2017.5 

     More details

    Event date: 2017.5

    Language:English  

    Country:United States  

  • Epicatechin Down-regulates Inflammatory Genes in Adipocytes Co-cultured with Endotoxin-activated Macrophages International conference

    The 95th General Session & Exhibition of the IADR  2017.3 

     More details

    Event date: 2017.3

    Language:English  

    Country:United States  

  • Epicatechin Down-regulates Adipose Tissue CCL19 Expression, Thereby Ameliorates Diet-induced Obesity International conference

    The 95th General Session & Exhibition of the IADR  2017.3 

     More details

    Event date: 2017.3

    Language:English  

    Country:United States  

  • IL-17Aは3T3-L1脂肪細胞におけるTNF-α誘導性IL-6・CCL20産生を相乗的に増強する

    佐野 朋美

    第145回日本歯科保存学会秋季学術大会  2016.10 

     More details

    Event date: 2017.2

    Language:Japanese  

    Venue:松本   Country:Japan  

  • エピカテキンは脂肪細胞‐マクロファージ相互作用による過剰な炎症反応を抑制する

    佐野 朋美

    第59回秋季日本歯周病学会学術大会  2016.10 

     More details

    Event date: 2017.2

    Language:Japanese  

    Venue:新潟   Country:Japan  

  • TLR-4リガンド刺激マクロファージと共存する脂肪細胞で発現するケモカインの網羅的解析

    佐野 朋美

    第55回春季日本歯周病学会学術大会  2012.5 

     More details

    Event date: 2016.5

    Language:Japanese  

    Venue:札幌コンベンションセンター(北海道)   Country:Japan  

  • CCL19-CCR7経路がエネルギー消費に及ぼす影響に関する検討

    佐野 朋美

    第58回春季日本歯周病学会学術大会  2015.5 

     More details

    Event date: 2015.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:幕張メッセ(千葉)   Country:Japan  

  • CCR7経路が肥満およびインスリン抵抗性に及ぼす影響に関する検討

    佐野 朋美

    第57回春季日本歯周病学会学術大会  2014.5 

     More details

    Event date: 2014.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長良川国際会議場(岐阜)   Country:Japan  

  • CCR7経路が肥満およびインスリン抵抗性に及ぼす影響に関する検討

    岩下 未咲, 佐野 朋美

    第57回日本糖尿病学会年次学術集会  2014.5 

     More details

    Event date: 2014.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪国際会議場(大阪)   Country:Japan  

▼display all

MISC

  • Epicatechin: Potential Use as Anti-Obese and Anti-Periodontal Nutrient Invited Reviewed

    Tomomi Sano, Malaz Elsheikh, Takashi Kanematsu

    Current Oral Health Reports   2024.9

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: 10.1007/s40496-024-00390-3

  • The Influence of Periodontal Burden on Metabolic Control of Diabetes - Myth or Reality? - from a Nutritional Perspective.

    Current Oral Health Reports   2017.6

     More details

    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Professional Memberships

  • Japanese Association for Oral Biology

  • The International Association for Dental Research

  • 日本薬理学会

  • 日本生化学会

Academic Activities

  • Screening of academic papers

    Role(s): Peer review

    2023

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

  • Screening of academic papers

    Role(s): Peer review

    2022

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:3

  • Screening of academic papers

    Role(s): Peer review

    2021

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

  • Screening of academic papers

    Role(s): Peer review

    2020

     More details

    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:4

Research Projects

  • miRNAを標的とした薬剤性歯肉増殖症新規治療薬の開発

    Grant number:24K12947  2024 - 2026

    日本学術振興会  科学研究費助成事業  基盤研究(C)

      More details

    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 組織慢性炎症を制御するM2マクロファージの機能解析研究

    Grant number:24K12872  2024 - 2026

    日本学術振興会  科学研究費助成事業  基盤研究(C)

      More details

    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • マクロファージ機能を制御するmiRNAを応用した新規歯周病治療薬の開発

    Grant number:23K09119  2023 - 2025

    日本学術振興会  科学研究費助成事業  基盤研究(C)

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • 歯肉増殖症や肥満に関わる新規分子SPOCK1のシグナリング経路の探索

    Grant number:21K09897  2021 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(C)

      More details

    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 抗腫瘍免疫を賦活化する新しい制癌シグナル分子の機能解明研究

    Grant number:21K09817  2021 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(C)

      More details

    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 肥満および歯周炎に共通のmiRNAを標的とした新規抗炎症治療薬の開発

    Grant number:20K18512  2020 - 2022

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • SPOCK-1生体タンパクを応用した安全性に優れた革新的歯周病予防薬の開発

    Grant number:19K22721  2019 - 2021

    日本学術振興会  科学研究費助成事業  挑戦的研究(萌芽)

      More details

    Authorship:Coinvestigator(s)  Grant type:Scientific research funding

  • 抗炎症miRNA内包エクソソームを用いた肥満糖尿病性歯周炎の新規治療法の開発

    Grant number:18K17071  2018 - 2020

    日本学術振興会  科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • エピカテキンの抗炎症効果の検証~脂肪組織炎症および実験的歯周炎モデルにおける検討

    Grant number:16H07067  2016 - 2017

    日本学術振興会  科学研究費助成事業  研究活動スタート支援

      More details

    Authorship:Principal investigator  Grant type:Scientific research funding

  • CCL19-CCR7経路を標的とした脂肪組織炎症および歯周炎抑制効果の検討

    2016

    平成28年度 研究活動基礎支援制度 ダイバーシティ研究環境実現イニシアティブ

      More details

    Authorship:Principal investigator  Grant type:On-campus funds, funds, etc.

▼display all

Class subject

  • 薬理学3

    2024.12 - 2025.2   Winter quarter

  • Aging Science and Pharmacology(Core) D

    2024.12 - 2025.2   Winter quarter

  • Aging Science and Pharmacology(Upper-grade) D

    2024.12 - 2025.2   Winter quarter

  • 臨床歯科薬理学

    2024.10 - 2024.12   Fall quarter

  • Aging Science and Pharmacology(Core) C

    2024.10 - 2024.12   Fall quarter

  • Aging Science and Pharmacology(Upper-grade) C

    2024.10 - 2024.12   Fall quarter

  • 薬理学2

    2024.6 - 2024.8   Summer quarter

  • Aging Science and Pharmacology(Core) B

    2024.6 - 2024.8   Summer quarter

  • Aging Science and Pharmacology(Upper-grade) B

    2024.6 - 2024.8   Summer quarter

  • Aging Science and Pharmacology(Core) A

    2024.4 - 2024.6   Spring quarter

  • Aging Science and Pharmacology(Upper-grade) A

    2024.4 - 2024.6   Spring quarter

  • 薬理学1

    2024.4 - 2024.6   Spring quarter

  • リサーチエクスポージャー

    2024.4 - 2024.6   Spring quarter

  • Aging Science and Pharmacology (Upper-grade) D

    2023.12 - 2024.2   Winter quarter

  • 薬理学3

    2023.12 - 2024.2   Winter quarter

  • Aging Science and Pharmacology(Core) D

    2023.12 - 2024.2   Winter quarter

  • Aging Science and Pharmacology (Upper-grade) C

    2023.10 - 2023.12   Fall quarter

  • 臨床歯科薬理学

    2023.10 - 2023.12   Fall quarter

  • Aging Science and Pharmacology(Core) C

    2023.10 - 2023.12   Fall quarter

  • Aging Science and Pharmacology (Upper-grade) B

    2023.6 - 2023.8   Summer quarter

  • 薬理学2

    2023.6 - 2023.8   Summer quarter

  • Aging Science and Pharmacology(Core) B

    2023.6 - 2023.8   Summer quarter

  • 歯科薬理学

    2023.4 - 2024.3   Full year

  • リサーチエクスポージャー

    2023.4 - 2024.3   Full year

  • 薬理学1

    2023.4 - 2023.6   Spring quarter

  • Aging Science and Pharmacology(Core) A

    2023.4 - 2023.6   Spring quarter

  • Aging Science and Pharmacology (Upper-grade) A

    2023.4 - 2023.6   Spring quarter

  • 歯科薬理学

    2022.4 - 2023.3   Full year

  • 口腔機能分子科学(低年次)

    2022.4 - 2023.3   Full year

  • 口腔機能分子科学(コア)

    2022.4 - 2023.3   Full year

  • リサーチエクスポージャー

    2022.4 - 2022.9   First semester

  • Advanced Dental Science Research(口腔機能分子科学)

    2021.4 - 2022.3   Full year

  • 歯科薬理学

    2021.4 - 2021.9   First semester

  • Advanced Dental Science Research(口腔機能分子科学)

    2020.12 - 2021.2   Winter quarter

  • 歯科薬理学

    2020.10 - 2021.3   Second semester

  • 歯周病学Ⅱ

    2020.4 - 2020.9   First semester

  • 総合歯科学

    2019.10 - 2020.3   Second semester

  • 歯周病学Ⅰ

    2019.10 - 2020.3   Second semester

  • 歯周病学Ⅱ

    2019.4 - 2019.9   First semester

  • 総合歯科学

    2018.10 - 2019.3   Second semester

  • 歯周病学Ⅱ

    2018.4 - 2018.9   First semester

  • 歯周病学Ⅰ

    2017.10 - 2018.3   Second semester

  • 総合歯科学

    2017.10 - 2018.3   Second semester

  • 総合歯科学

    2016.10 - 2017.3   Second semester

▼display all

FD Participation

  • 2020.6   Role:Participation   Title:ジャーナルをめぐる現状と論文の投稿・入手について

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2019.6   Role:Participation   Title:科研費申請のススメ

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2018.10   Role:Panelist   Title:馬出地区3部局合同男女共同参画FD

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2018.8   Role:Participation   Title:IR室による歯学研究院の研究力分析

    Organizer:[Undergraduate school/graduate school/graduate faculty]

  • 2018.3   Role:Participation   Title:東京医歯大における国家試験対策の実践

    Organizer:[Undergraduate school/graduate school/graduate faculty]

Year of medical license acquisition

  • 2011