2025/04/17 更新

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写真a

ヤタベ ルイ
矢田部 塁
YATABE RUI
所属
システム情報科学研究院 情報エレクトロニクス部門 学術研究員
職名
学術研究員
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メールアドレス
電話番号
0928023762
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機能性材料を用いた匂いセンサの研究開発を行っている。 味覚センサにも使用される脂質高分子膜などのソフトマテリアルの表面の分析なども行っている。これらの分析に用いる機器の開発も行っている。有機無機問わず分析の分野にかかわっている。
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学位

  • 工学博士

経歴

  • 京セラ株式会社   

    京セラ株式会社

  • なし   

研究テーマ・研究キーワード

  • 研究テーマ: 表面分析用分光分析装置の開発

    研究キーワード: 表面分析 分光分析

    研究期間: 2016年7月 - 2020年3月

  • 研究テーマ: 機能性材料を用いた匂いセンサの研究

    研究キーワード: 匂い センサ

    研究期間: 2015年4月 - 2018年3月

  • 研究テーマ: 味覚センサ用脂質高分子膜の表面解析

    研究キーワード: 有機 表面分析 味覚センサ 脂質高分子膜

    研究期間: 2014年3月 - 2016年7月

  • 研究テーマ: 1.表面プラズモン共鳴(SPR)センサと抗原抗体反応を用いた低分子量物質の高感度検知のためのセンサの開発。主に表面開始原子移動ラジカル重合を用いてポリマー表面でセンサを作製している。 2.味覚センサに用いられる脂質高分子膜の構造解析も行っている。

    研究キーワード: 表面プラズモン共鳴, 表面開始原子移動ラジカル重合, 抗原抗体反応, トリニトロトルエン

    研究期間: 2011年4月 - 2018年3月

受賞

  • 第16回(2012年)応用物理学会九州支部発表奨励賞

    2012年12月   応用物理学会九州支部   表面開始原子移動ラジカル重合を用いたSPRセンサチップの作製

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    In this study, we modified a surface plasmon resonance immunosensor chip with a polymer using surface-initiated atom transfer polymerization (SI-ATRP) for the highly sensitive detection of 2,4,6-trinitrotoluene (TNT). To immobilize a TNT analogue on the polymer, mono-2-(methacryloyloxy)ethylsuccinate (MES), which has a carboxyl group was used in this study. However, the anti-TNT antibody may adsorb non-specifically on the polymer surface by an electrostatic interaction because MES is negatively charged. Therefore, a mixed monomer with MES and diethylaminoethylmethacrylate (DEAEM), which has a tertiary amino group and is positively charged, was prepared to obtain electro neutrality for suppressing the nonspecific adsorption. The detection of TNT was performed by inhibition assay using the polymer surface. To obtain high sensitivity to TNT, the affinity between the surface and the antibody was optimized with controlling the density of the initiator for ATRP by mixing two types of self-assembled monolayer reagents. As a result, a limit of detection of 5.7 pg/mL (ppt) was achieved for TNT using the optimized surface.

論文

  • Analysis of a lipid/polymer membrane for bitterness sensing with a preconditioning process

    Yatabe Rui

    Sensors   15 ( 9 )   2015年9月

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    記述言語:英語  

  • Fabrication of surface plasmon resonance sensor surface with control of the non-specific adsorption and affinity for the detection of 2,4,6-trinitrotoluene using an antifouling copolymer 招待 査読 国際誌

    Yatabe Rui, Takeshi Onodera, Kiyoshi Toko

    frontiers in BIOENGINEERING AND BIOTECHNOLOGY   2 ( 10 )   2014年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    We fabricated a surface plasmon resonance (SPR) sensor using a hydrophilic polymer for the highly sensitive detection of 2,4,6-trinitrotoluene (TNT). The hydrophilic polymer was made from mono-2-(methacryloyloxy)ethylsuccinate (MES) and 2-hydroxyethylmethacrylate (HEMA) by surface-initiated atom transfer radical polymerization. The detection ofTNTwas carried out by displacement assay with the SPR measurement. In displacement assay, the affinity between anti-TNT antibody and the sensor surface, affects to the sensitivity. In the SPR measurement, non-specific adsorption should be controlled because SPR sensor cannot discriminate between specific and non-specific adsorption. Therefore, the affinity and non-specific adsorption were controlled by changing the ratio of HEMA to MES. A detection limit of 0.4 ng/ml (ppb) for TNT was achieved using a sensor surface with the lowest affinity without non-specific adsorption.

    DOI: 10.3389/fbioe.2014.00010

  • Fabrication of an SPR Sensor Surface with Antifouling Properties Using Surface Initiated Atom Transfer Polymerization for Highly Sensitive Detection of 2,4,6-Trinitrotoluene

    Yatabe Rui, Takeshi Onodera, Kiyoshi Toko

    Sensors   13   9294 - 9304   2013年7月

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    記述言語:英語  

    DOI: doi:10.3390/s130709294

  • Highly Sensitive Detection of 2,4,6-trinitrotoluene (TNT) Using Poly(vinylamine-co-N-vinylformamide) Based Surface Plasmon Resonance (SPR) Immunosensor

    Yatabe Rui, Takeshi Onodera, Kiyoshi Toko

    Sensors and Materials   25 ( 1 )   45 - 56   2013年1月

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    記述言語:英語  

  • Development of two-dimensional qualitative visualization method for isoflavones secreted from soybean roots using sheets with immobilized bovine serum albumin. 国際誌

    Takeshi Onodera, Haruna Miyazaki, Xinzhu Li, Jin Wang, Masaru Nakayasu, Rui Yatabe, Yusuke Tahara, Ai Hosoki, Nozomu Sakurai, Akifumi Sugiyama

    Biosensors & bioelectronics   196   113705 - 113705   2022年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    A visualization method for the qualitative evaluation of soybean isoflavones secreted from soybean roots by transferring them onto a sheet with immobilized bovine serum albumin (BSA) was developed. BSA was chemically bonded onto a glass microfiber filter. The fluorescence quenching resulting from the interaction of BSA with soybean isoflavones such as daidzein and daidzin was utilized. Fluorescence images before and after soybean roots were placed in contact with the sheets with immobilized BSA were taken with an electron-multiplying charge-coupled device camera. The fluorescence quenching in the images was visualized and analyzed. Soybean isoflavones were extracted from the sheets for quantitative analysis, and the correlation coefficient between the quenched fluorescence intensity per sheet and the total amount of soybean isoflavones was 0.78 (p < 0.01), indicating a high correlation. The quenched fluorescence intensity was lower in pumpkin roots, which do not secrete soybean isoflavone. It was found from analyzed images that soybean isoflavone is secreted in larger amounts from the basal region of the taproot and the tips of the lateral roots of soybean.

    DOI: 10.1016/j.bios.2021.113705

  • Odor recognition of thermal decomposition products of electric cables using odor sensing arrays

    Yuanchang Liu, Shintaro Furuno, Sosuke Akagawa, Rui Yatabe, Takeshi Onodera, Nobuyuki Fujiwara, Hidekazu Takeda, Seiichi Uchida, Kiyoshi Toko

    Chemosensors   9 ( 9 )   2021年9月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    An odor sensing system with chemosensitive resistors was used to identify the gases generated from overheated cables to prevent fire. Three different electric cables for a distribution cabi-net were used. The cables had an insulation layer made of polyvinyl chloride (PVC) or cross-linked polyethylene (XLPE). The heat resistance of the cables was tested by differential thermal and ther-mogravimetric analyses. The thermal decomposition products of the cables were investigated by gas chromatography-mass spectrometry (GC-MS). For the odor sensing system, two types of 16-channel array were used to detect the generated gases. One contains high-polarity GC stationary phase materials and the other contains GC stationary phase materials of high to low polarity. The system could distinguish among three cable samples at 270 °C with an accuracy of about 75&#37; through both arrays trained with machine learning. Furthermore, the system could achieve a recall rate of 90&#37; and a precision rate of 70&#37; when the abnormal temperature was set above the cables’ allowable conductor temperature at 130 °C. The odor sensing system could effectively detect the abnormal heating of the cables before the occurrence of fire. Therefore, it is helpful for fire prediction and detection systems in factories and substations.

    DOI: 10.3390/chemosensors9090261

  • Erratum: Ink-jet printed, blended polymer-based microdisk resonators for controlling non-specific adsorption of biomolecules: Publisher's note (Optics Letters (2021) 46:13 (262-265) DOI: 10.1364/OL.412993)

    Abdul Nasir, Rui Yatabe, Yuya Mikami, Hiroaki Yoshioka, Nilesh Vasa, Yuji Oki

    Optics Letters   46 ( 13 )   3070   2021年7月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    This publisher's note contains corrections toOpt. Lett. 46, 262 (2021).

    DOI: 10.1364/OL.433647

  • Fully room temperature and label free biosensing based on an ink-jet printed polymer microdisk laser

    Abdul Nasir, Yuaya Mikami, Rui Yatabe, Hiroaki Yoshioka, Nilesh Vasa, Yuji Oki

    Optical Materials Express   11 ( 3 )   592 - 602   2021年3月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    Materials with biomolecule-compatible functional groups are desirable for the fabrication of microdisk lasers used in bio-sensing applications. In this study, a microdisk laser was fabricated using a low-viscosity hyper branched polymer FC-V-50 using ink-jet printing, and was surface-modified at room temperature within a relatively short time compared to conventional methods. The carboxyl functional group of the FC-V-50 polymer was used for surface modification and biotinylation. The adsorption characteristics of the microdisk laser were evaluated using bovine serum albumin, avidin, and streptavidin. This study reports the first demonstration of label-free biosensing using the FC-V-50 polymer-based microdisk laser.

    DOI: 10.1364/OME.415000

  • Odor Sensor System Using Chemosensitive Resistor Array and Machine Learning

    Rui Yatabe, Atsushi Shunori, Bartosz Wyszynski, Yosuke Hanai, Atsuo Nakao, Masaya Nakatani, Akio Oki, Hiroaki Oka, Takashi Washio, Kiyoshi Toko

    IEEE Sensors Journal   21 ( 2 )   2077 - 2083   2021年1月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    In this study, we developed an odor sensor system using chemosensitive resistors, which outputted multichannel data. Mixtures of gas chromatography stationary materials (GC materials) and carbon black were used as the chemosensitive resistors. The interaction between the chemosensitive resistors and gas species shifted the electrical resistance of the resistors. Sixteen different chemosensitive resistors were fabricated on an odor sensor chip. In addition, a compact measurement instrument was fabricated. Sixteen channel data were obtained from the measurements of gas species using the instrument. The data were analyzed using machine learning algorithms available on Weka software. As a result, the sensor system successfully identified alcoholic beverages. Finally, we demonstrated the classification of restroom odor in a field test. The classification was successful with an accuracy of 97.9&#37;.

    DOI: 10.1109/JSEN.2020.3016678

  • Ink-jet printed, blended polymer-based microdisk resonators for controlling non-specific adsorption of biomolecules

    Abdul Nasir, Rui Yatabe, Yuya Mikami, Hiroki Yoshioka, Nilesh Vasa, Yuji Oki

    Optics Letters   46 ( 2 )   262 - 265   2021年1月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    A blended FC-V-50 and TZ-001 polymer-based microdisk laser was fabricated by the ink-jet printing method and used for biosensing applications. The FC-V-50 polymer has a negative charge due to the presence of carboxyl functional groups, and the TZ-001 polymer has a positive charge due to the tertiary amine group at a pH of seven. In biosensing applications, non-specific adsorption due to opposite charges of biomolecules and microdisk surfaces can adversely affect the performance of the biosensor. By mixing FC-V-50 and TZ-001 polymers in different ratios, the microdisk surface charge was controlled, and the non-specific adsorption of bovine serum albumin and lysozyme was studied. In addition, the label-free biosensing of streptavidin was demonstrated using a blended polymer-based microdisk laser. This work reports, to the best of our knowledge, the first demonstration of a blended polymer microdisk laser for controlling the non-specific adsorption of biomolecules.

    DOI: 10.1364/OL.412993

  • Effect of Edge Angle of Ink-Jet Printed Microdisk Lasers on Mode Shift Due to Protein Adsorption

    Abdul Nasir, Yuya Mikami, Taku Takagishi, Rui Yatabe, Hiroaki Yoshioka, Nilesh Vasa, Yuji Oki

    2020 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2020 - Proceedings   2020年8月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    Hyper branched polymer FC-V-50 based microdisk lasers with different edge angles were fabricated by ink-jet printing method. Then, effect of edge angle on mode shift was investigated by monitoring the physical adsorption of BSA protein.

    DOI: 10.1364/CLEOPR.2020.C2D_2

  • Surfactant cleaning of lipid polymer membranes of bitterness sensor

    Xiao Wu, Yapeng Yuan, Yusuke Tahara, Rui Yatabe, Hidekazu Ikezaki, Kiyoshi Toko

    ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings   2019年5月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    The bitterness sensor with negatively charged lipid polymer membrane has been reported to perform high sensitivity and selectivity to bitterness of medicines. However, the conventional cleaning solution cannot completely remove residual substances after measuring high concentration bitter samples. Surfactant is an important cleaning agent used for membrane materials. This paper reported the effects of four kinds of surfactants in cleaning the lipid polymer membrane of the bitterness sensor. Among these surfactants, anionic surfactant linear alkylbenzene sulfonate (LAS) showed no detectable impact on membrane integrity and a good cleaning effect for the bitterness sensor.

    DOI: 10.1109/ISOEN.2019.8823187

  • Multichannel Odor Sensor System using Chemosensitive Resistors and Machine Learning

    Atsushi Shunori, Rui Yatabe, Bartosz Wyszynski, Yosuke Hanai, Atsuo Nakao, Masaya Nakatani, Akio Oki, Hiroaki Oka, Takashi Washio, Kiyoshi Toko

    ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings   2019年5月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    In this study, we have fabricated multichannel odor sensor using chemosensitive resistors. The chemosensitive resistors were made from complex of carbon black and gas chromatography stationary materials (GC materials). The electrical resistance of the chemosensitive resistor changed by sensing gas species. We have fabricated an odor sensor chip, which had 16 types of chemosensitive resistors. In addition, we developed a measurement instrument with compact size. The odor sensor chip was embedded in the instrument to construct an odor sensor system. The sensor system outputted the data of 16 channels if sensing gas species. The data have been analyzed using machine learning algorithms that were available on software Weka. As a result, it was successful to identify alcohol beverages by sensing their odor using the sensor system.

    DOI: 10.1109/ISOEN.2019.8823511

  • Field-effect transistor array modified by a stationary phase to generate informative signal patterns for machine learning-assisted recognition of gas-phase chemicals

    Toshihiro Yoshizumi, Tatsuro Goda, Rui Yatabe, Akio Oki, Akira Matsumoto, Hiroaki Oka, Takashi Washio, Kiyoshi Toko, Yuji Miyahara

    Molecular Systems Design and Engineering   4 ( 2 )   386 - 389   2019年4月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    We propose an artificial intelligence-based chemical-sensing system integrating a porous gate field-effect transistor (PGFET) array modified by gas chromatography stationary phase materials and machine-learning techniques. The chemically sensitive PGFET array generates cross-reactive signals for computational analysis and shows potential for applications to compact intelligent sensing devices, including mobile electronic noses.

    DOI: 10.1039/c8me00097b

  • An SPR sensor chip based on peptide-modified single-walled carbon nanotubes with enhanced sensitivity and selectivity in the detection of 2,4,6-trinitrotoluene explosives

    Jin Wang, Sanyang Du, Takeshi Onodera, Rui Yatabe, Masayoshi Tanaka, Mina Okochi, Kiyoshi Toko

    Sensors (Switzerland)   18 ( 12 )   2018年12月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    In this study, we developed a surface plasmon resonance (SPR) sensor chip based on 2,4,6-trinitrotoluene (TNT) recognition peptide-modified single-walled carbon nanotubes (SWCNTs). The carboxylic acid-functionalized SWCNTs were immobilized on a 3-aminopropyltriethoxysilane (APTES)-modified SPR Au chip surface. Through π-stacking between the aromatic amino acids and SWCNTs, the TNT recognition peptide TNTHCDR3 was immobilized onto the surface of the SWCNTs. The peptide–SWCNTs-modified sensor surface was confirmed and evaluated by atomic force microscope (AFM) observation. The peptide–SWCNTs hybrid SPR sensor chip exhibited enhanced sensitivity with a limit of detection (LOD) of 772 ppb and highly selective detection compared with commercialized carboxymethylated dextran matrix sensor chips.

    DOI: 10.3390/s18124461

  • Highly Selective Rational Design of Peptide-Based Surface Plasmon Resonance Sensor for Direct Determination of 2,4,6-trinitrotoluene (TNT) Explosive

    Jin Wang, Masaki Muto, Rui Yatabe, Yusuke Tahara, Takeshi Onodera, Masayoshi Tanaka, Mina Okochi, Kiyoshi Toko

    Sensors and Actuators, B: Chemical   264   279 - 284   2018年7月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    In this study, 2,4,6-trinitrotoluene (TNT) binding peptide was synthesized and screened for TNT specific detection using surface plasmon resonance (SPR) sensor. The TNT binding peptide was rational design and synthesized through amino acid sequence from complementarity determining region (CDR) in the anti-TNT monoclonal antibody, which was produced from hybridoma cell using TNP-KLH conjugate as antigen. Three TNT binding peptide sequences were obtained from the heavy chain of CDR1 named TNTHCDR1, TNTHCDR2 from CDR2 and TNTHCDR3 from CDR3 of anti-TNT antibody. Screening process of three candidate peptides were carried out by using the SPR sensor with direct determination, which the peptide was directly immobilized on the sensor chip CM7 surface through amine coupling reaction. The results demonstrated that peptide TNTHCDR3 was determined as TNT binding peptide and no non-specific binding was observed. The selectivity of TNT binding peptide TNTHCDR3 was also testified by six kinds of TNT analogues. The results indicated the specific binding between TNT and peptide TNTHCDR3.

    DOI: 10.1016/j.snb.2018.02.075

  • Laser-induced damage threshold test for interfacial analysis of lipid polymer membrane

    Satoshi Ikezawa, Yusuke Tahara, Rui Yatabe, Masatoshi Kozaki, Kiyoshi Toko

    Proceedings of the International Conference on Sensing Technology, ICST   2017-December   1 - 4   2018年2月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    This paper describes a preliminary test for sum-frequency generation (SFG) spectroscopy analysis of lipid polymer membranes. The SFG technique is used to analyze surface and structural information of molecules at gas-solid, gas-liquid, liquid-solid interfaces. A specially designed SFG system, which allows to analyze orientational polarization of polymer molecules at interfaces between a lipid polymer membrane and liquid/gas/solid, is being developed in our laboratory. A laser-induced damage threshold test of lipid polymer membranes was conducted in an early stage of this work.

    DOI: 10.1109/ICSensT.2017.8304474

  • Improved durability and sensitivity of bitterness-sensing membrane for medicines

    Xiao Wu, Hideya Onitake, Zhiqin Huang, Takeshi Shiino, Yusuke Tahara, Rui Yatabe, Hidekazu Ikezaki, Kiyoshi Toko

    Sensors (Switzerland)   17 ( 11 )   2017年11月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    This paper reports the improvement of a bitterness sensor based on a lipid polymer membrane consisting of phosphoric acid di-n-decyl ester (PADE) as a lipid and bis(1-butylpentyl) adipate (BBPA) and tributyl o-acetylcitrate (TBAC) as plasticizers. Although the commercialized bitterness sensor (BT0) has high sensitivity and selectivity to the bitterness of medicines, the sensor response gradually decreases to almost zero after two years at room temperature and humidity in a laboratory. To reveal the reason for the deterioration of the response, we investigated sensor membranes by measuring the membrane potential, contact angle, and adsorption amount, as well as by performing gas chromatography-mass spectrometry (GC-MS), liquid chromatography-tandem mass spectrometry (LC-MS/MS).We found that the change in the surface charge density caused by the hydrolysis of TBAC led to the deterioration of the response. The acidic environment generated by PADE promoted TBAC hydrolysis. Finally, we succeeded in fabricating a new membrane for sensing the bitterness of medicines with higher durability and sensitivity by adjusting the proportions of the lipid and plasticizers.

    DOI: 10.3390/s17112541

  • Rational design of peptide-functionalized surface plasmon resonance sensor for specific detection of TNT explosive

    Jin Wang, Masaki Muto, Rui Yatabe, Takeshi Onodera, Masayoshi Tanaka, Mina Okochi, Kiyoshi Toko

    Sensors (Switzerland)   17 ( 10 )   2017年10月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    In this study, a rationally-designed 2,4,6-trinitrotoluene (TNT) binding peptide derived from an amino acid sequence of the complementarity-determining region (CDR) of an anti-TNT monoclonal antibody was used for TNT detection based on a maleimide-functionalized surface plasmon resonance (SPR) sensor. By antigen-docking simulation and screening, the TNT binding candidate peptides were obtained as TNTHCDR1 derived from the heavy chain of CDR1, TNTHCDR2 derived from CDR2, and TNTHCDR3 from CDR3 of an anti-TNT antibody. The binding events between candidate peptides and TNT were evaluated using the SPR sensor by direct determination based on the 3-aminopropyltriethoxysilane (APTES) surface. The TNT binding peptide was directly immobilized on the maleimide-functionalized sensor chip surface from N-γ-maleimidobutyryl-oxysuccinimide ester (GMBS). The results demonstrated that peptide TNTHCDR3 was identified and selected as a TNT binding peptide among the other two candidate peptides. Five kinds of TNT analogues were also investigated to testify the selectivity of TNT binding peptide TNTHCDR3. Furthermore, the results indicated that the APTES-GMBS-based SPR sensor chip procedure featured a great potential application for the direct detection of TNT.

    DOI: 10.3390/s17102249

  • Array of chemosensitive resistors with composites of gas chromatography (GC) materials and carbon black for detection and recognition of VOCs: A basic study

    Bartosz Wyszynski, Rui Yatabe, Atsuo Nakao, Masaya Nakatani, Akio Oki, Hiroaki Oka, Kiyoshi Toko

    Sensors (Switzerland)   17 ( 7 )   2017年7月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    Mimicking the biological olfaction, large odor-sensor arrays can be used to acquire a broad range of chemical information, with a potentially high degree of redundancy, to allow for enhanced control over the sensitivity and selectivity of artificial olfaction systems. The arrays should consist of the largest possible number of individual sensing elements while being miniaturized. Chemosensitive resistors are one of the sensing platforms that have a potential to satisfy these two conditions. In this work we test viability of fabricating a 16-element chemosensitive resistor array for detection and recognition of volatile organic compounds (VOCs). The sensors were fabricated using blends of carbon black and gas chromatography (GC) stationary-phase materials preselected based on their sorption properties. Blends of the selected GC materials with carbon black particles were subsequently coated over chemosensitive resistor devices and the resulting sensors/arrays evaluated in exposure experiments against vapors of pyrrole, benzenal, nonanal, and 2-phenethylamine at 150, 300, 450, and 900 ppb. Responses of the fabricated 16-element array were stable and differed for each individual odorant sample, proving the blends of GC materials with carbon black particles can be effectively used for fabrication of large odor-sensing arrays based on chemosensitive resistors. The obtained results suggest that the proposed sensing devices could be effective in discriminating odor/vapor samples at the sub-ppm level.

    DOI: 10.3390/s17071606

  • Development of sweetness sensor for high-potency sweeteners using lipid polymer membrane

    Yusuke Tahara, Tomohiro Hattori, Xiao Wu, Rui Yatabe, Hidekazu Ikezaki, Masaaki Habara, Kiyoshi Toko

    ISOEN 2017 - ISOCS/IEEE International Symposium on Olfaction and Electronic Nose, Proceedings   2017年7月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    High-potency sweeteners are applied to low-calorie diets and bitterness-masking ingredients in pharmaceutical products. We have studied taste sensors with lipid polymer membranes based on potentiometric measurement system for high-potency sweeteners. However, the sensor also responds to astringency substances because of hydrophobic characteristics of the lipid polymer membrane. In this study, we developed a new taste sensor using a lipid polymer membrane for saccharin sodium and acesulfame potassium as negatively charged high-potency sweeteners. We optimized the quantities and types of lipids and plasticizers for the fabrication of the sensor with high selectivity and sensitivity. We succeeded in the fabrication of the new sensor, the output of which could be suppressed under-5 mV for astringency substances. Moreover, the sensor has a good sensitivity and selectivity for saccharin sodium and acesulfame potassium.

    DOI: 10.1109/ISOEN.2017.7968932

  • Molecularly imprinted sol-gel-based QCM sensor arrays for the detection and recognition of volatile aldehydes

    Chuanjun Liu, Bartosz Wyszynski, Rui Yatabe, Kenshi Hayashi, Kiyoshi Toko

    Sensors (Switzerland)   17 ( 2 )   2017年2月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    The detection and recognition of metabolically derived aldehydes, which have been identified as important products of oxidative stress and biomarkers of cancers; are considered as an effective approach for early cancer detection as well as health status monitoring. Quartz crystal microbalance (QCM) sensor arrays based on molecularly imprinted sol-gel (MISG) materials were developed in this work for highly sensitive detection and highly selective recognition of typical aldehyde vapors including hexanal (HAL); nonanal (NAL) and bezaldehyde (BAL). The MISGs were prepared by a sol-gel procedure using two matrix precursors: tetraethyl orthosilicate (TEOS) and tetrabutoxytitanium (TBOT). Aminopropyltriethoxysilane (APT); diethylaminopropyltrimethoxysilane (EAP) and trimethoxy-phenylsilane (TMP) were added as functional monomers to adjust the imprinting effect of the matrix. Hexanoic acid (HA); nonanoic acid (NA) and benzoic acid (BA) were used as psuedotemplates in view of their analogous structure to the target molecules as well as the strong hydrogen-bonding interaction with the matrix. Totally 13 types of MISGs with different components were prepared and coated on QCM electrodes by spin coating. Their sensing characters towards the three aldehyde vapors with different concentrations were investigated qualitatively. The results demonstrated that the response of individual sensors to each target strongly depended on the matrix precursors; functional monomers and template molecules. An optimization of the 13 MISG materials was carried out based on statistical analysis such as principle component analysis (PCA); multivariate analysis of covariance (MANCOVA) and hierarchical cluster analysis (HCA). The optimized sensor array consisting of five channels showed a high discrimination ability on the aldehyde vapors; which was confirmed by quantitative comparison with a randomly selected array. It was suggested that both the molecularly imprinting (MIP) effect and the matrix effect contributed to the sensitivity and selectivity of the optimized sensor array. The developed MISGs were expected to be promising materials for the detection and recognition of volatile aldehydes contained in exhaled breath or human body odor.

    DOI: 10.3390/s17020382

  • Taste sensor using strongly hydrophobic membranes to measure hydrophobic substances

    Xiao Wu, Ke Ji, Rixin Wang, Yusuke Tahara, Rui Yatabe, Kiyoshi Toko

    Proceedings of the International Conference on Sensing Technology, ICST   2016年12月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    A taste sensor using a lipid/polymer membrane, i.e., an electronic tongue with global selectivity, has been developed for objective evaluation of the taste of foods and beverages. Moreover, the taste sensor has been also contributing to safety of foods, e.g., the sensor membrane with strong hydrophobicity was used to detect sodium dodecyl sulfate (SDS), a negatively charged surfactant, which was generally added into the pesticide because of its strongly melting effect. An immersion process in monosodium glutamate (MSG) solution, called 'MSG preconditioning' was needed to obtain the change in membrane electric potential caused by adsorption (CPA) for sensor membrane before measurement. However, what happened to sensor membrane during MSG preconditioning is unclear. In this paper, we examined the relationship between the CPA value and the period of MSG preconditioning. The amount of adsorbed SDS and MSG was measured to figure out whether the CPA value is related to the amount of adsorption. As a result, with the precondition process progressed, the CPA values showed concentration dependence on SDS concentration, and increased to a peak by preconditioning for one day then decreased to a stable state after that. The amount of adsorbed SDS depended on the SDS concentration but did not change with the increasing of preconditioning time. In conclusion, we revealed that the most suitable time of MSG preconditioning for the membrane for SDS was one day. The CPA value was affected by both the surface charge density and the amount of absorption.

    DOI: 10.1109/ICSensT.2016.7796341

  • Quantitative prediction of bitterness masking effect of high-potency sweeteners using taste sensor

    Xiao Wu, Hideya Onitake, Tamami Haraguchi, Yusuke Tahara, Rui Yatabe, Miyako Yoshida, Takahiro Uchida, Hidekazu Ikezaki, Kiyoshi Toko

    Sensors and Actuators, B: Chemical   235   11 - 17   2016年11月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    A taste sensor based on lipid/polymer membranes has been reported being possible to detect the masking of bitter substances or masking on bitterness receptors (physical masking or biochemical masking). However, it was difficult to express the bitterness suppression by sweeteners, which is decided by the balance of substances produced in human's brain (functional masking). High-potency sweeteners are one of the sweeteners used for bitterness-masking in food and pharmaceutical industry. The objective of this study is to evaluate the bitterness-masking effect of high-potency sweeteners using the taste sensor. A bitterness sensor was used to evaluate the bitterness of quinine hydrochloride, and sweetness sensors for high-potency sweeteners were used to evaluate the sweetness of aspartame and saccharine sodium. The sensory evaluation was also carried out to examine the bitterness suppression effect of high-potency sweeteners. The bitterness-prediction formulas were proposed with the aid of a model regression analysis using two outputs from the bitterness sensor and the sweetness sensor for high-potency sweeteners. As a result, the predicted bitterness showed a good correlation with the human taste when aspartame or saccharine sodium was added to quinine hydrochloride. Thus, this study provided an effective method to evaluate the bitterness suppressed by high-potency sweeteners.

    DOI: 10.1016/j.snb.2016.05.009

  • Research on the changes to the lipid/polymer membrane used in the acidic bitterness sensor caused by preconditioning

    Yuhei Harada, Junpei Noda, Rui Yatabe, Hidekazu Ikezaki, Kiyoshi Toko

    Sensors (Switzerland)   16 ( 2 )   2016年2月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    A taste sensor that uses lipid/polymer membranes can evaluate aftertastes felt by humans using Change in membrane Potential caused by Adsorption (CPA) measurements. The sensor membrane for evaluating bitterness, which is caused by acidic bitter substances such as iso-alpha acid contained in beer, needs an immersion process in monosodium glutamate (MSG) solution, called “MSG preconditioning”. However, what happens to the lipid/polymer membrane during MSG preconditioning is not clear. Therefore, we carried out three experiments to investigate the changes in the lipid/polymer membrane caused by the MSG preconditioning, i.e., measurements of the taste sensor, measurements of the amount of the bitterness substance adsorbed onto the membrane and measurements of the contact angle of the membrane surface. The CPA values increased as the preconditioning process progressed, and became stable after 3 d of preconditioning. The response potentials to the reference solution showed the same tendency of the CPA value change during the preconditioning period. The contact angle of the lipid/polymer membrane surface decreased after 7 d of MSG preconditioning; in short, the surface of the lipid/polymer membrane became hydrophilic during MSG preconditioning. The amount of adsorbed iso-alpha acid was increased until 5 d preconditioning, and then it decreased. In this study, we revealed that the CPA values increased with the progress of MSG preconditioning in spite of the decrease of the amount of iso-alpha acid adsorbed onto the lipid/polymer membrane, and it was indicated that the CPA values increase because the sensor sensitivity was improved by the MSG preconditioning.

    DOI: 10.3390/s16020230

  • Research on the Changes to the Lipid/Polymer Membrane Used in the Acidic Bitterness Sensor Caused by Preconditioning

    Yatabe Rui

    Sensors   16   2016年2月

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    記述言語:英語  

    DOI: doi:10.3390

  • Analysis of a lipid/polymer membrane for bitterness sensing with a preconditioning process

    Rui Yatabe, Junpei Noda, Yusuke Tahara, Yoshinobu Naito, Hidekazu Ikezaki, Kiyoshi Toko

    Sensors (Switzerland)   15 ( 9 )   22439 - 22450   2015年9月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    It is possible to evaluate the taste of foods or medicines using a taste sensor. The taste sensor converts information on taste into an electrical signal using several lipid/polymer membranes. A lipid/polymer membrane for bitterness sensing can evaluate aftertaste after immersion in monosodium glutamate (MSG), which is called “preconditioning”. However, we have not yet analyzed the change in the surface structure of the membrane as a result of preconditioning. Thus, we analyzed the change in the surface by performing contact angle and surface zeta potential measurements, Fourier transform infrared spectroscopy (FTIR), X-ray photon spectroscopy (XPS) and gas cluster ion beam time-of-flight secondary ion mass spectrometry (GCIB-TOF-SIMS). After preconditioning, the concentrations of MSG and tetradodecylammonium bromide (TDAB), contained in the lipid membrane were found to be higher in the surface region than in the bulk region. The effect of preconditioning was revealed by the above analysis methods.

    DOI: 10.3390/s150922439

  • Development and investigation of a sweetness sensor for sugars -effect of lipids- 査読 国際誌

    Masato Yasuura, Qingyue Shen, Yatabe Rui, Kiyoshi Toko

    Sensors and Materials   Vol.27 ( No.5 )   351 - 358   2015年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  • Sensitive detection of 2,4,6-trinitrotoluene by surface plasmon fluorescence spectroscopy

    Satoshi Ito, Shuhei Tanaka, Rui Yatabe, Takeshi Onodera, Kiyoshi Toko

    Proceedings of IEEE Sensors   2014-December ( December )   325 - 328   2014年12月

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    記述言語:その他   掲載種別:研究論文(その他学術会議資料等)  

    We developed a compact measurement system for surface plasmon fluorescence spectroscopy (SPFS) and a sensor surface for the detection of 2,4,6-trinitrotoluene (TNT). We employed a laser diode as a light source in the optical system for exciting fluorescence. Then, a fan-shaped beam was irradiated from the laser diode to a Au thin film using a beam expander. Fluorescence emission was captured using a photomultiplier detector. The sensor surface was modified with TNT analogues via a self-assembled monolayer. A limit of detection in the ppt range for TNT was obtained using a fluorescence-labeled anti- TNT monoclonal antibody in the SPFS system by indirect competitive assay.

    DOI: 10.1109/ICSENS.2014.6984999

  • Sensitive Detection of Capsaicinoids Using a Surface Plasmon Resonance Sensor with Anti-Homovanillic Acid Polyclonal Antibodies

    Shingo Nakamura, Yatabe Rui, Takeshi Onodera, Kiyoshi Toko

    Biosensors   3   374 - 384   2013年11月

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    記述言語:英語  

    DOI: 10.3390/bios3040374

  • Fabrication of an SPR sensor surface with antifouling properties for highly sensitive detection of 2,4,6-trinitrotoluene using surface-initiated atom transfer polymerization

    Rui Yatabe, Takeshi Onodera, Kiyoshi Toko

    Sensors (Switzerland)   13 ( 7 )   9294 - 9304   2013年7月

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    記述言語:その他   掲載種別:研究論文(学術雑誌)  

    In this study, we modified a surface plasmon resonance immunosensor chip with a polymer using surface-initiated atom transfer polymerization (SI-ATRP) for the highly sensitive detection of 2,4,6-trinitrotoluene (TNT). To immobilize a TNT analogue on the polymer, mono-2-(methacryloyloxy)ethylsuccinate (MES), which has a carboxyl group, was used in this study. However, the anti-TNT antibody may adsorb non-specifically on the polymer surface by an electrostatic interaction because MES is negatively charged. Therefore, a mixed monomer with MES and diethylaminoethylmethacrylate (DEAEM), which has a tertiary amino group and is positively charged, was prepared to obtain electroneutrality for suppressing the nonspecific adsorption. The detection of TNT was performed by inhibition assay using the polymer surface. To ensure high sensitivity to TNT, the affinity between the surface and the antibody was optimized by controlling the density of the initiator for ATRP by mixing two types of self-assembled monolayer reagents. As a result, a limit of detection of 5.7 pg/mL (ppt) for TNT was achieved using the optimized surface. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

    DOI: 10.3390/s130709294

  • Preparation and Characteristics of Rat Anti-1,3,5-Trinitroperhydro-1,3,5-Triazine (RDX) Monoclonal Antibody and Detection of RDX Using Surface Plasmon Resonance Immunosensor

    Yusuke Tanaka, Yatabe Rui, Kazutaka Nagatomo, Takeshi Onodera, Kiyoshi Matsumoto, Kiyoshi Toko

    IEEE Sensors Journal   13 ( 11 )   4452 - 4458   2013年6月

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    記述言語:英語  

    DOI: 10.1109/JSEN.2013.2269697

  • Photo-rechargeable Battery Based on Photo-induced Copper Intercalation into Quasi-One-Dimensional Compound KFeS2

    Shogo Takenoshita, Yatabe Rui, Masatoshi Kozaki, Hisao Kuriyaki, Kiyoshi Toko

    Extended Abstracts of the 2011 Conference on Solid State Devices and Materials   326 - 327   2011年9月

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    記述言語:英語  

▼全件表示

講演・口頭発表等

  • SI-ATRPを用いたSPRセンサチップにおける非特異吸着の抑制

    矢田部 塁, 小野寺 武, 都甲 潔

    応用物理学会九州支部学術講演会  2013年11月 

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    開催年月日: 2013年11月 - 2013年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:長崎大学   国名:日本国  

  • 表面開始原子移動ラジカル重合を用いたSPRセンサチップの作製

    矢田部 塁, 小野寺 武, 都甲 潔

    応用物理学会九州支部学術講演会  2012年12月 

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    開催年月日: 2012年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:佐賀大学   国名:日本国  

  • 擬1次元化合物KFeS2膜電極の作製

    矢田部 塁, 栗焼 久夫

    応用物理学会九州支部学術講演会  2004年11月 

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    開催年月日: 2004年11月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:琉球大学   国名:日本国  

  • 擬1次元カルコゲン化合物の2次電池への適用(Ⅱ)

    矢田部 塁, 西森 喬, 栗焼 久夫

    応用物理学会九州支部学術講演会  2003年12月 

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    開催年月日: 2003年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:長崎ハウステンボス   国名:日本国  

  • 表面開始原子移動ラジカル重合を用いたSPR免疫センサによるTNTの高感度検出

    矢田部 塁, 小野寺 武, 都甲 潔

    応用物理学会学術講演会  2013年3月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:神奈川工科大学   国名:日本国  

  • ポリビニルアミンを用いたSPRセンサチップの開発

    矢田部 塁, 小野寺 武, 都甲 潔

    応用物理学会学術講演会  2012年3月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:早稲田大学   国名:日本国  

  • ポリビニルアミンを用いたSPR免疫センサによるTNT高感度検出

    矢田部 塁, 小野寺 武, 都甲 潔

    電気学会センサ・マイクロマシン部門総合研究会  2012年6月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:京都大学   国名:日本国  

  • Fabrication of the SPR sensor chip by Surface Initiated-Atom Transfer Radical Polymerization 国際会議

    矢田部 塁, 小野寺 武, 都甲 潔

    JSPS若手研究者派遣プロジェクト  2013年1月 

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    記述言語:英語   会議種別:シンポジウム・ワークショップ パネル(公募)  

    開催地:九州大学   国名:日本国  

  • ポリビニルアミンを用いたSPRセンサ表面の開発

    石井 良典, 矢田部 塁, 小野寺 武, 都甲 潔

    電気学会全国大会  2014年3月 

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    開催年月日: 2014年3月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:愛媛大学   国名:日本国  

  • 表面プラズモン増強蛍光分光測定装置に用いるセンサ表面の開発

    伊藤 智, 田中 秀平, 矢田部 塁, 小野寺 武, 都甲 潔

    電気学会全国大会  2014年3月 

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    開催年月日: 2014年3月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:愛媛大学   国名:日本国  

  • 表面プラズモン共鳴センサを用いたフルフラールの検出

    羅 浩宇, 馬 苗苗, 田 勝煕, 矢田部 塁, 小野寺 武, 中本 高道, 都甲 潔

    電気学会全国大会  2014年3月 

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    開催年月日: 2014年3月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:愛媛大学   国名:日本国  

  • 表面プラズモン共鳴バイオセンサを用いた体臭成分の検知

    小野寺 武, 馬 苗苗, 羅 浩宇, 矢田部 塁, 中本 高道, 都甲 潔

    電子情報通信学会技術研究報告  2014年1月 

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    開催年月日: 2014年1月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:佐賀大学   国名:日本国  

  • 表面プラズモン共鳴センサを用いた体臭成分の検知

    小野寺 武, 馬 苗苗, 矢田部 塁, 中本 高道, 都甲 潔

    応用物理学会九州支部学術講演会  2013年11月 

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    開催年月日: 2013年11月 - 2013年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:長崎大学   国名:日本国  

  • フォーカシングATR法を用いた表面プラズモン増強蛍光分光測定装置の開発

    田中 秀平, 矢田部 塁, 伊藤 智, 小野寺 武, 都甲 潔

    応用物理学会九州支部学術講演会  2013年11月 

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    開催年月日: 2013年11月 - 2013年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:長崎大学   国名:日本国  

  • 擬1次元化合物KFeS2膜電極の作製(Ⅱ)

    中村 豪, 松尾 龍馬, 矢田部 塁, 栗焼 久夫

    応用物理学会九州支部学術講演会  2005年11月 

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    開催年月日: 2005年11月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:福岡工業大学   国名:日本国  

  • 擬1次元カルコゲン化合物の2次電池への適用(Ⅰ)

    西森 喬, 矢田部 塁, 栗焼 久夫

    応用物理学会九州支部学術講演会  2003年12月 

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    開催年月日: 2003年12月

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:長崎ハウステンボス   国名:日本国  

  • 擬1次元化合物KFeS2の電極材料特性

    西森 喬, 矢田部 塁, 栗焼 久夫

    応用物理学会学術講演会  2003年8月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  • 擬1次元化合物KFeS2の低温ヨウ素熱処理

    栗焼 久夫, 竹中 幹一郎, 矢田部 塁

    日本物理学会  2004年3月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:九州大学   国名:日本国  

  • Photo-rechargeable Battery Based on Photo-induced Copper Intercalation into Quasi-One-Dimensional Compound KFeS2 国際会議

    竹之下 翔吾, 矢田部 塁, 神崎 雅俊, 栗焼 久夫, 都甲 潔

    2011 International Conference on Solid State Devices and Materials (SSDM2011)  2011年9月 

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    記述言語:英語   会議種別:口頭発表(一般)  

    国名:日本国  

  • 擬一次元化合物KFeS2へのCuイオンインターカレーション

    竹之下 翔吾, 矢田部 塁, 神崎 雅俊, 栗焼 久夫, 都甲 潔

    応用物理学会学術講演会  2011年9月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  • KFeS2電極の多孔質化による充電量の改善

    工藤 靖明, 竹之下 翔吾, 矢田部 塁, 栗焼 久夫, 都甲 潔

    応用物理学会学術講演会  2012年3月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:早稲田大学   国名:日本国  

  • SENSITIVE DETECTION OF LOW-MOLECULAR WEIGHT SUBSTANCES USING SPR IMMUNOSENSOR 国際会議

    小野寺 武, 矢田部 塁, 田中 裕輔, 中村 真悟, 都甲 潔

    China-Japan Join Symposium on Sensing Technology  2012年4月 

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    記述言語:英語   会議種別:口頭発表(一般)  

    国名:中華人民共和国  

  • RDX高感度検出のための表面プラズモン共鳴免疫センサ

    田中 裕輔, 矢田部 塁, 中村 真悟, 小野寺 武, 都甲 潔

    電気関係学会九州支部連合大会  2012年9月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  • 水晶振動子マイクロバランスセンサを用いたコルチゾール検出

    可 凱丹, 田原 祐助, 小野寺 武, 矢田部 塁, 栗焼 久夫, 都甲 潔

    応用物理学会九州支部学術講演会  2012年12月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:佐賀大学   国名:日本国  

  • 表面プラズモン共鳴(SPR)免疫センサを用いた唾液中ストレスバイオマーカーの高感度検出

    切通 哲朗, 田原 祐助, 小野寺 武, 矢田部 塁, 都甲 潔

    応用物理学会九州支部学術講演会  2012年12月 

     詳細を見る

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:佐賀大学   国名:日本国  

  • 表面プラズモン共鳴(SPR)免疫センサを用いたカプサイシンの高感度検出

    中村 真悟, 矢田部 塁, 田中 裕輔, 小野寺 武, 都甲 潔

    応用物理学会九州支部学術講演会  2012年12月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:佐賀大学   国名:日本国  

  • Development of Surface Plasmon Resonance Biosensor for Antibiotic 国際会議

    小野寺 武, Praveen Singh, 矢田部 塁, 海野 薫, 都甲 潔

    JSPS若手研究者派遣プロジェクト  2013年1月 

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    記述言語:英語   会議種別:口頭発表(一般)  

    開催地:九州大学   国名:日本国  

  • 表面プラズモン共鳴(SPR)免疫センサを用いたカプサイシノイドの検出

    田 勝煕, 馬 苗苗, 安浦 雅人, 矢田部 塁, 小野寺 武, 都甲 潔

    電気学会センサ・マイクロマシン部門総合研究会  2013年8月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  • 表面プラズモン共鳴免疫センサを用いたフルフラールの検出

    馬 苗苗, 田 勝煕, 田中 秀平, 矢田部 塁, 小野寺 武, 都甲 潔

    電気関係学会九州支部連合大会  2013年9月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  • Measurement System for Surface Plasmon Fluorescence Spectroscopy Using ATR Method with Focused Beam 国際会議

    田中 秀平, 矢田部 塁, 小野寺 武, 都甲 潔

    The 10th Asian Conference on Chemical Sensors  2013年11月 

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    記述言語:英語   会議種別:口頭発表(一般)  

    国名:タイ王国  

  • 表面プラズモン共鳴センサを用いたフルフラールの検出

    羅 浩宇, 馬 苗苗, 田 勝煕, 矢田部 塁, 小野寺 武, 中本 高道, 都甲 潔

    電気学会全国大会  2014年1月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

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所属学協会

  • 応用物理学会