YASUO SHINOBU
Organization
Faculty of Agriculture Department of Bioresource Sciences Professor
Graduate School of Bioresource and Bioenvironmental Sciences Department of Bioresource Sciences（Concurrent）
School of Agriculture Department of Bioresource and Bioenvironment（Concurrent）
Graduate School of Bioresource and Bioenvironmental Sciences Department of Bioresource Sciences（Concurrent）
School of Agriculture Department of Bioresource and Bioenvironment（Concurrent）
Title
Professor
Profile
In organisms living in temperate zones, various biological functions are regulated by seasonal changes in environment (i.e., photoperiod), including metabolism, immune functions, stress responses, affect, and reproduction. The photoperiodic responses are associated with the circadian clock (internal clock) and its main output hormones, melatonin or glucocorticoids. We are trying to clarify the molecular mechanisms of photoperiodic responses, focusing on brain and peripheral organs of mammmals by means of molecular, morphological, physiological, and functional techniques. This study is important for not only the control of animal production but also therapeutic target for the seasonal affective disorder in human.
Disruption of the circadian clock by irregular light-dark cycles, e.g., shift work or irregular light exposure, is a serious problem in the world. Numerous studies report that the circadian disruption increases risk of many diseases such as cancer. We are trying to identify functional nutrients that can ameliorate or prevent the circadian disruption caused by irregular light-dark cycles, and to clarify the effect of dietary rhythms on the clock-associated physiology and behavior.
External link
Research Areas
Research Areas
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Life Science / Nutrition science and health science
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Life Science / Animal production science
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Life Science / Animal life science
Degree
Degree
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Ph.D (agriculture)
Research History
Research History
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Kyushu University Professor
2024.10 - Present
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Kyushu University Faculty of Agriculture Professor
2022.4 - Present
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Kyushu University Faculty of Agriculture Associate Professor
2009.12 - 2022.4
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2004.01~2005.10 名古屋大学大学院生命農学研究科 産官学連携研究員 2005.11~2007.10 Institute of Anatomy II, Goethe University Frankfurt, 日本学術振興会海外特別研究員 2007.11~2009.11 Institute of Anatomy II, Goethe University Frankfurt, 博士研究員
Education
Education
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Nagoya University 大学院生命農学研究科
- 2003.12
Research Interests・Research Keywords
Research Interests・Research Keywords
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Research theme： Mechanisms underlying interactions among multi-scale rhythms including seasonal, sexual, and circadian rhythms
Keyword： 季節、性周期、概日時計、陶器うつ
Research period： 2024.10
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Research theme： Studies on cyclic environment and stress physiology
Keyword： stress, environmental enrichment, brain
Research period： 2019.3
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Research theme： Effect of dietary rhythms on brain functions
Keyword： Dietary rhythm, mouse, behavior, neuron
Research period： 2017.4 - 2025.3
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Research theme： Effect of photoperiod during early life stages on learning, memory, neurodevelopment, and metabolism in adulthood.
Keyword： photoperiodism, neurogenesis, neuronal network, affective behaviors, body weight, metabolism
Research period： 2014.4
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Research theme： Search of amino acids that affect the circadian clock
Keyword： amino acids, circadian clock, mouse
Research period： 2010.12 - 2018.3
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Research theme： Chrononutritional studies on the circadian disruption: approach using chronic jet lag mice
Keyword： circadian disruption, chronic jet lag, mouse
Research period： 2010.4
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Research theme： Mechanisms controlling photoperiodic responses in metabolism and mood
Keyword： metabolism, stress, seasonal affective disorder, brain
Research period： 2009.12
Awards
Awards
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九州大学農学研究院賞
2016.1 九州大学農学研究院
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文部科学大臣表彰 若手科学者賞
2015.4 文部科学省 哺乳類の季節リズムに関する基盤研究
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季節性感情障害（冬季うつ病）の病態を反映するマウスモデルを世界に先駆けて見出し、その制御機構の一端を解明した。本研究成果は、季節性感情障害の研究に強力なツールを提供するもので、新しい治療法や予防法の研究開発を飛躍的に発展させると期待される。
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日本時間生物学会学術奨励賞
2010.11 日本時間生物学会 脊椎動物の光周性を支配する脳内メカニズムの解明
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Young Investigator Award of European Biological Rhythms Society
2009.9 Organizing committee of the meeting for 11th Congress of the European Biological Rhythms Society Identification of endocannabinoid in the hypophysial pars tuberalis of the Syrian hamster and its possible role for seasonal prolactin secretion
Papers
Papers
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Nishino, D; Haginouchi, T; Shimogiri, T; Muroya, S; Kawabata, K; Urasoko, S; Oshima, I; Yasuo, S; Gotoh, T
METABOLITES 15 ( 3 ) 2025.3 （ ISSN:2218-1989 eISSN:2218-1989 ）
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Language：English Publisher：Metabolites
Objectives: This study investigated the long-term effects of maternal undernutrition on overall muscle metabolism, growth performance, and muscle characteristics in postnatal offspring of Wagyu (Japanese Black) cattle. Methods: Wagyu cows were divided into nutrient-adequate (control, CNT; n = 4, 120% of requirements) and nutrient-restricted groups (NR; n = 4; 60% of requirements), and treated from day 35 of gestation until parturition. Diets were delivered on the basis of crude protein requirements, meeting 100% and 80% of dry matter requirements in CNT and NR groups, respectively. All offspring were provided with the same diet from birth to 300 days of age (d). Longissimus thoracis muscle (LM) samples were collected from the postnatal offspring. Results: The NR offspring had lower birth body weight, but their body weight caught up before weaning. These offspring showed enhanced efficiency in nutrient utilization during the post-weaning growth period. Comprehensive analyses of metabolites and transcripts revealed the accumulation of proteinogenic amino acid, asparagine, in NR offspring LM at 300 d, while the abundance of nicotinamide adenine dinucleotide (NADH) and succinate were reduced. These changes were accompanied by decreased gene expression of nicotinamide phosphoribosyltransferase (NAMPT), NADH: ubiquinone oxidoreductase subunit A12 (NDUFA12), and NADH dehydrogenase subunit 5 (ND5), which are essential for mitochondrial energy production. Additionally, NR offspring LM exhibited decreased abundance of neurotransmitter, along with a higher proportion of slow-oxidative myofibers and a lower proportion of fast-oxidative myofibers at 300 d. Conclusions: Offspring from nutrient-restricted cows might suppress muscle energy production, primarily in the mitochondria, and conserve energy expenditure for muscle protein synthesis. These findings suggest that maternal undernutrition programs a thrifty metabolism in offspring muscle, with long-term effects.
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Matsuda, M; Nishi, T; Yoshida, Y; Terada, Y; Matsuda-Hayama, C; Kumamoto, T; Hamamura, K; Kohro-Ikeda, E; Yasuo, S; Koyanagi, S; Matsunaga, N; Ohdo, S
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 752 151470 2025.3 （ ISSN:0006-291X eISSN:1090-2104 ）
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Language：English Publisher：Biochemical and Biophysical Research Communications
Circadian rhythm alterations are related to the onset and severity of various diseases. The expression of the dopamine receptor D3 (DRD3) is regulated by clock genes, and DRD3 functional abnormalities are linked to various neurological diseases. However, the relationship between DRD3 function and circadian machinery is unclear. Here, we demonstrate the influence of DRD3 on the circadian machinery. Although the expression of DRD3 in mouse suprachiasmatic nucleus (SCN) did not show a circadian rhythm, the expression of Per1 mRNA was altered in the SCN of Drd3 knockout (Drd3−/−) mice compared to that in wild-type (WT) mice. These differences were caused by the upregulation of the DRD3–extracellular signal–regulated kinase–cAMP response element binding protein (DRD3–ERK–CREB) signaling pathway in cultured cells and SCN. In addition, Drd3−/− mice demonstrated increased period length of locomotor activity than WT mice only under constant dark conditions. Expression of clock genes in the liver, which does not express DRD3, was affected by the loss of DRD3 only under constant dark conditions, similar to that in the SCN. These results suggest that DRD3 expressed in the SCN regulates the central clock via endogenous ligands and affects peripheral organs. This may provide new evidence to unravel the relationship between dopamine neurotransmission and the circadian clock, which has not yet been fully elucidated.
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Yasuo, S
ZOOLOGICAL SCIENCE 42 ( 1 ) 2025.2 （ ISSN:0289-0003 ）
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Language：English Publisher：Zoological science
For the survival and efficient breeding of wild-living animals, it is crucial to predict seasonal changes and prepare appropriate physiological functions and neurobehavioral mechanisms. In mammals, photoperiod serves as a reliable cue for seasonal changes in the environment, primarily transmitted by melatonin. This review focuses on the seasonal adaptation of mammalian development, specifically the effect of early-life photoperiod on reproductive, somatic, and neurobehavioral development in small- and large-sized mammals. Prediction of seasons through early-life photoperiod is particularly important for small mammals, which have relatively short longevity, to adjust their maximum growth and breeding ability in appropriate seasons during the birth year or the following round. Brain plasticity, as well as cognitive and emotional behaviors, are also highly modulated by early-life photoperiods for successful mating and spatial memory for foraging. This review first summarizes the basic knowledge and recent progress in the programming and epigenetic regulatory mechanisms of reproductive and neurobehavioral development in small mammals, including C57BL/6J mice, which cannot produce detectable amounts of melatonin. The review then focuses on the influence of perinatal environmental conditions or birth season on adult phenotypes in large livestock and humans. Studies have advanced on the concept of the developmental origins of health and disease (DOHaD). Evidence from large mammals suggests that the prediction of seasons is crucial for high-fitness functions over several years. Finally, this review discusses the association of the season of birth with life course physiology and diseases in humans, and the possible mechanisms.
DOI： 10.2108/zs240059
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Sex-dependent effects of chronic jet lag on circadian rhythm and metabolism in mice
Ma, TT; Matsuo, R; Kurogi, K; Miyamoto, S; Morita, T; Shinozuka, M; Taniguchi, F; Ikegami, K; Yasuo, S
BIOLOGY OF SEX DIFFERENCES 15 ( 1 ) 102 2024.12 （ eISSN:2042-6410 ）
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Language：English Publisher：Biology of Sex Differences
頻繁に明暗周期をずらして長期的にマウスの時差ぼけ状態を誘導する「慢性的時差ぼけ条件」において、メスの体内時計がオスよりも乱れやすいことを発見した。また、オスでは当該条件で過剰な体重増加や耐糖能異常が生じる一方で、メスでは体重減少が見られるなど、性別により代謝異常の現れ方が大きく異なることを見出した。さらに、精巣を摘出したオスでは、メスのように体内時計が時差ぼけに対して乱れやすくなり、テストステロンを投与すると強靭性が回復したことから、テストステロンがオス特有の慢性的時差ぼけ反応の鍵であることを解明した。
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Mukai, K; Qiu, XC; Takai, Y; Yasuo, S; Oshima, Y; Shimasaki, Y
ANTIOXIDANTS 13 ( 7 ) 2024.7 （ ISSN:2076-3921 eISSN:2076-3921 ）
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Language：English Publisher：Antioxidants
Diurnal rhythms in physiological functions contribute to homeostasis in many organisms. Although relationships between molecular biology and diurnal rhythms have been well studied in model organisms like higher plants, those in harmful algal bloom species are poorly understood. Here we measured several physiological parameters and the expression patterns of photosynthesis-related and antioxidant-enzyme genes in the Chattonella marina complex to understand the biological meaning of diurnal rhythm. Under a light–dark cycle, Fv/Fm and expression of psbA, psbD, and 2-Cys prx showed significant increases in the light and decreases during the dark. These rhythms remained even under continuous dark conditions. DCMU suppressed the induction of psbA, psbD, and 2-Cys prx expression under both light regimes. Oxidative stress levels and H2O2 scavenging activities were relatively stable, and there was no significant correlation between H2O2 scavenging activities and antioxidant-enzyme gene expression. These results indicate that the Chattonella marina complex has developed mechanisms for efficient photosynthetic energy production in the light. Our results showed that this species has a diurnal rhythm and a biological clock. These phenomena are thought to contribute to the efficiency of physiological activities centered on photosynthesis and cell growth related to the diurnal vertical movement of this species.
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Prostaglandin F2α Affects the Cycle of Clock Gene Expression and Mouse Behavior. International journal
Yuya Tsurudome, Yuya Yoshida, Kengo Hamamura, Takashi Ogino, Sai Yasukochi, Shinobu Yasuo, Ayaka Iwamoto, Tatsuya Yoshihara, Tomoaki Inazumi, Soken Tsuchiya, Toru Takeo, Naomi Nakagata, Shigekazu Higuchi, Yukihiko Sugimoto, Akito Tsuruta, Satoru Koyanagi, Naoya Matsunaga, Shigehiro Ohdo
International journal of molecular sciences 25 ( 3 ) 2024.2 （ ISSN:1661-6596 eISSN:1422-0067 ）
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Language：English Publishing type：Research paper (scientific journal) Publisher：International Journal of Molecular Sciences
Prostaglandins are bioactive compounds, and the activation of their receptors affects the expression of clock genes. However, the prostaglandin F receptor (Ptgfr) has no known relationship with biological rhythms. Here, we first measured the locomotor period lengths of Ptgfr-KO (B6.129-Ptgfrtm1Sna) mice and found that they were longer under constant dark conditions (DD) than those of wild-type (C57BL/6J) mice. We then investigated the clock gene patterns within the suprachiasmatic nucleus in Ptgfr-KO mice under DD and observed a decrease in the expression of the clock gene cryptochrome 1 (Cry1), which is related to the circadian cycle. Moreover, the expression of Cry1, Cry2, and Period2 (Per2) mRNA were significantly altered in the mouse liver in Ptgfr-KO mice under DD. In the wild-type mouse, the plasma prostaglandin F2α (PGF2α) levels showed a circadian rhythm under a 12 h cycle of light-dark conditions. In addition, in vitro experiments showed that the addition of PTGFR agonists altered the amplitude of Per2::luc activity, and this alteration differed with the timing of the agonist addition. These results lead us to hypothesize that the plasma rhythm of PGF2α is important for driving clock genes, thus suggesting the involvement of PGF2α- and Ptgfr-targeting drugs in the biological clock cycle.
DOI： 10.3390/ijms25031841
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Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion. International journal
Kaito Kurogi, Fuka Taniguchi, Ryohei Matsuo, Marina Shinozuka, Raiki Suzaki, Shinobu Yasuo
European journal of pharmacology 960 176126 - 176126 2023.12 （ ISSN:0014-2999 eISSN:1879-0712 ）
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Language：English Publishing type：Research paper (scientific journal) Publisher：European Journal of Pharmacology
Psycho-environmental stress-based animal models of anxiety and depression are useful for investigating pathological mechanisms and drug development. Although several rodent-based studies have reported the beneficial effects of environmental enrichment (EE) on brain plasticity and anxiety- and depression-like behaviors, other studies have reported inverse effects. Here, we found that housing male mice in EE involving large cages and other EE materials increased anxiety- and depression-like behaviors in open field and tail suspension tests (TST). We further confirmed that housing in large cages was sufficient to induce increased depression-like behaviors in the TST and reduce the saccharine preference percentage, a sign of anhedonia, in male mice. In these experiments, the number of animals per cage was equivalent to that in standard cage housing, suggesting that low density in large cages may be a determining factor for behavioral alteration. In mice housed in large cages, sex-specific dysregulation of brain monoamine systems was observed; dopamine turnover to homovanillic acid or norepinephrine in the prefrontal cortex was elevated in males, while serotonin turnover to 5-hydroxyindoleacetic acid in the amygdala was increased in females. Finally, we demonstrated that daily intraperitoneal injections of bupropion, a dopamine and norepinephrine reuptake inhibitor, counteracted large-cage housing-induced changes in depression- and anhedonia-like behaviors in male mice. Our results suggest that housing in large cages with a low density of mice is a novel paradigm to clarify the mechanisms of environmental stress-induced emotional dysregulation and to identify drugs or food factors to alleviate the dysregulation.
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Temporal patterns of increased growth hormone secretion in mice after oral administration of L- ornithine: possible involvement of ghrelin receptors Reviewed International journal
Emi Taniguchi, Ayumi Hattori, Kaito Kurogi, Yukihiro Hishida, Fumiko Watanabe, Mitsuhiro Furuse, Shinobu Yasuo
The Journal of Veterinary Medical Science 84 1283 - 1287 2022.9
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Language：English Publishing type：Research paper (scientific journal)
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Intake of l-serine before bedtime prevents the delay of the circadian phase in real life Reviewed International journal
Michihiro Ohashi, Sang-Il Lee, Taisuke Eto, Nobuo Uotsu, Chie Tarumizu, Sayuri Matsuoka, Shinobu Yasuo, Shigekazu Higuchi
Journal of Physiological Anthropology 41 ( 1 ) 31 2022.8 （ ISSN:1880-6805 eISSN:1880-6805 ）
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Language：English Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC
Abstract
Background
It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid l-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of l-serine before bedtime on circadian phase in real life and whether its effect depends on the initial circadian phase.
Methods
The subjects were 33 healthy male and female university students and they were divided into an l-serine group (n = 16) and a placebo group (n = 17). This study was conducted in a double-blind manner in autumn and winter. After a baseline period for 1 week, the subjects took 3.0 g of l-serine or a placebo 30 min before bedtime for 2 weeks. Saliva was collected twice a week at home every hour under a dim light condition from 20:00 to 1 h after habitual bedtime. Dim light melatonin onset (DLMO) was used as an index of phase of the circadian rhythm.
Results
DLMO after intervention was significantly delayed compared to the baseline DLMO in the placebo group (p = 0.02) but not in the l-serine group. There was a significant difference in the amount of changes in DLMO between the two groups (p = 0.04). There were no significant changes in sleeping habits after intervention in the two groups. There were significant positive correlations between advance of DLMO and DLMO before intervention in the l-serine group (r = 0.53, p < 0.05) and the placebo group (r = 0.69, p < 0.01). There was no significant difference in the slopes of regression lines between the two groups (p = 0.71), but the intercept in the l-serine group was significantly higher than that in the placebo group (p < 0.01). The levels of light exposure were not significantly different between the two groups.
Conclusions
Our findings suggest that intake of l-serine before bedtime for multiple days might attenuate the circadian phase delay in the real world and that this effect does not depend on the initial circadian phase.
Trial registration
This study is registered with University Hospital Medical Information Network in Japan (UMIN000024435. Registered on October 17, 2016).DOI： 10.1186/s40101-022-00306-z
Other Link： https://link.springer.com/article/10.1186/s40101-022-00306-z/fulltext.html
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Effect of regular and irregular stimulation cycles of dexamethasone on circadian clock in NIH3T3 cells. Reviewed International journal
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
Chronobiology international 39 ( 1 ) 1 - 9 2022.1 （ ISSN:0742-0528 eISSN:1525-6073 ）
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Language：English Publishing type：Research paper (scientific journal) Publisher：Chronobiology International
Animal studies have shown that irregular light-dark cycles cause circadian desynchronization, while few studies have addressed the effect of regular/irregular stimulation cycles of signaling hormones on the cellular clock in vitro. Here, we examined how cellular clocks respond to regular and irregular stimulation cycles of dexamethasone, using NIH3T3 cells transfected with the Bmal1 promoter-driven luciferase (Bmal1-Luc) reporter gene. Cyclic stimulation with dexamethasone at different time intervals (18-28 h, 3 times regularly) revealed that Bmal1-Luc bioluminescence rhythms can be entrained to 22 and 24 h cycles during the stimulation period, but not to other cycles. The rhythm entrained for 24 h cycles persisted for at least one day after the last stimulation. Irregular dexamethasone treatment (16, 24, and 16 h, sequentially; short-term jet lag protocol) resulted in an overall upregulation and phase shifts of the temporal expression of several clock genes and cell cycle genes, including c-Myc and p53. Regular dexamethasone stimulation three times with 24 h cycles also caused upregulation of Per1 and Per2 expression, but not c-Myc and p53 expression. In conclusion, our study identified the entrainable range of the circadian clock in NIH3T3 cells to the dexamethasone stimulation cycle and demonstrated that irregular dexamethasone treatment could disturb the expression of cell cycle genes.
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Spermidine resets circadian clock phase in NIH3T3 cells. Reviewed
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
Biomedical research (Tokyo, Japan) 42 ( 5 ) 221 - 227 2021.9
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Irregular light-dark cycles desynchronize the circadian clock via hormonal and neuronal pathways and increase the risk of various diseases. This study demonstrated that a single pulse of spermidine-a polyamine-strongly induced circadian phase advances in the presence or absence of dexamethasone (a synthetic glucocorticoid) in NIH3T3 cells transfected with the Bmal1 promotor-driven luciferase reporter gene. The spermidine-induced phase advances were 2-3 fold greater than were the dexamethasone-induced shifts. The phase resetting effect of spermidine occurred in a dose- and time-dependent manner and was not blocked by RU486, an antagonist of glucocorticoid receptors. Spermidine treatment modulated the expression of clock genes within 60 min, which was sooner than changes in the expression of autophagy-related genes. These findings suggested that spermidine is a potent modulator of the circadian phase, acting through glucocorticoid receptor-independent pathways, and may be useful for treating diseases related to circadian desynchrony.
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Photoperiodic changes in hippocampal neurogenesis and plasma metabolomic profiles in relation to depression-like behavior in mice Invited Reviewed International journal
Emi Taniguchi, Ayako Tashiro, Ayumi Hattori, Mitsuhiro Furuse, Shinobu Yasuo
Behavioural Brain Research, 402:113100 402 113100 2021.4
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Language：English Publishing type：Research paper (scientific journal)
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Effect of postnatal photoperiod on DNA methylation dynamics in the mouse brain Reviewed
Nozomu Takaki, Tatsuhiro Uchiwa, Mitsuhiro Furuse, Shinobu Yasuo
Brain Research 1733 2020.4
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Season of birth influences the onset of psychiatric diseases in mammals. Recent studies using rodent models have revealed that photoperiod during early life stages has a strong impact on affective and cognitive behaviors, neuronal activity, and hippocampal neurogenesis/astrogenesis in later life. The present study examined the effect of postnatal photoperiod on global DNA methylation and hydroxymethylation dynamics in the mouse brain. Male mice born under short-day (SD) conditions were divided into SD and long-day (LD) groups on the day of birth. Temporal expression of DNA methyltransferases (DNMT1/3a) with 5-methylcytosine (5-mC) levels, as well as protein levels of ten-eleven translocation (TET) 2 with 5-hydroxymethylcytosine (5-hmC) levels, were analyzed from postnatal day 4 (P4) to P21. Levels of 5-hmC in all hippocampal areas were higher in the LD group than in the SD group at P21, with a positive correlation between 5-hmC levels and TET2 levels throughout the experimental period. Inconsistent results were observed between DNMT1/3a mRNA levels and 5-mC levels. On the other hand, in the OB, mRNA levels of DNMT1 and DNMT3a were slightly lower in the LD group similar to 5-mC levels, but TET2 and 5-hmC levels were not influenced by the photoperiod. In conclusion, postnatal exposure of mice to LD conditions induces an increase in TET2-dependent DNA hydroxymethylation in the hippocampus, which might be involved in the long-term effects of postnatal photoperiod on neurogenesis and affective/cognitive behaviors.
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Naho Morisaki, Chie Nagata, Shinobu Yasuo, Seiichi Morokuma, Kiyoko Kato, Masafumi Sanefuji, Eiji Shibata, Mayumi Tsuji, Ayako Senju, Toshihiro Kawamoto, Shoichi Ohga, Koichi Kusuhara
British Journal of Nutrition 120 ( 12 ) 1432 - 1440 2018.12
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Clinical trials show that protein supplement increases infant size in malnourished populations; however, epidemiological studies in high-income countries have reported mixed results. Although these findings suggest a non-linear relationship between maternal macronutrient intake and fetal growth, this relationship has not been closely examined. We assessed the association between maternal protein intake and fetal growth among 91 637 Japanese women with singletons in a nation-wide cohort study using validated FFQ. The respondents answered the FFQ twice, once during early pregnancy (FFQ1; 16·3 (sd 6·0) weeks), and second during mid-pregnancy (FFQ2, 28·1 (sd 4·1) weeks). Daily energy intake and percentage energy from protein, fats and carbohydrates were 7477 (sd 2577) kJ and 13·5 (sd 2·0), 29·5 (sd 6·5) and 55·3 (sd 7·8) %, respectively, for FFQ1, and 7184 (sd 2506) kJ and 13·6 (sd 2·1), 29·8 (sd 6·6) and 55·3 (sd 7·9) %, respectively, for FFQ2. The average birth weight was 3028 (sd 406) g, and 6350 infants (6·9 %) were small for gestational age (SGA). In both phases of the survey, birth weight was highest and the risk of SGA was lowest when the percentage energy from protein was 12 %, regardless of whether isoenergetic replacement was with fat or carbohydrates. Furthermore, when protein density in the maternal diet was held constant, birth weight was highest when 25 % of energy intake came from fat and 61 % came from carbohydrates during early pregnancy. We found maternal protein intake to have an inverse U-curve relationship with fetal growth. Our results strongly suggest that the effect of protein on birth weight is non-linear, and that a balanced diet fulfilling the minimum requirement for all macronutrients was ideal for avoiding fetal growth restriction.
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Early-life photoperiod influences depression-like behavior, prepulse inhibition of the acoustic startle response, and hippocampal astrogenesis in mice Reviewed International journal
Yusuke Takaia, Misato Kawaia, Tadashi Ogob, Takashi Ichinoseb, Shigeki Furuyab, Nozomu Takakia, Yukihiro Tonea, Hiroshi Udoc, Mitsuhiro Furusea, Shinobu Yasuoa
Neuroscience 374 133 - 143 2018.3
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Maternal stress during the lactation period rather than the gestation period strongly influences the amino acid composition in milk and affects growth and behaviour in offspring
Tkkuma Nishigawa, Satsuki Nagamachi, Mayumi Takakura, Hiromi Ikeda, Momoko Kodaira, Takeshi Yamaguchi, Vishwajit Surchowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Journal of the Faculty of Agriculture, Kyushu University 63 ( 1 ) 61 - 70 2018.2
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Language：English Publishing type：Research paper (scientific journal)
It is well known that maternal stress during the gestation and lactation periods induces abnormal behavior in the offspring and causes a lowering of the offspring's body weight. However, the negative effects of maternal stress on the mother's milk, which is one of the most important connecting factors between mothers and their offspring, are not yet fully understood. The present study aimed to investigate how free amino acids in milk, as well as the growth and behavior of offspring, are changed by maternal stress during the gestation and lactation periods. Although maternal stress during the gestation period did not affect the growth of offspring or the free amino acid composition in the milk, the offspring in the stressed group showed lower locomotor activity. However, maternal stress during the lactation period caused a reduction in body weight in the offspring following the stress load. It increased the concentration in the milk of several amino acids, such as taurine, aspartic acid and β-alanine, while it decreased the concentration of most of the free amino acids in the maternal plasma. Notably, the body weight of offspring at postnatal age 11 days was negatively correlated with taurine concentration in the milk. These results show that maternal stress during the lactation period may have a great impact on the free amino acid composition of the milk, which may partly, but not entirely, be the cause of lower body weight in the offspring.
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Satsuki Nagamachi, Takuma Nishigawa, Mayumi Takakura, Hiromi Ikeda, Momoko Kodaira, Takeshi Yamaguchi, Vishwajit Sur Chowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Journal of Veterinary Medical Science 80 ( 2 ) 235 - 241 2018.2
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The growth of offspring is affected not only by the protein in maternal milk but also by the free amino acids (FAAs) contained in it. L-Serine (L-Ser) is known as an important FAA for the development of the central nervous system and behavioral activity. However, it is not clear whether L-Ser is transported into the pool of FAAs contained in milk and thereby affects the growth of offspring. Using mice, the current study investigated the effects of dietary L-Ser during pregnancy and lactation on milk and plasma FAA composition, as well as on growth, behavior, and plasma FAAs of offspring. Dietary L-Ser did not significantly affect the maternal, anxiety-like, or cognitive behaviors of either the dam or the offspring. The FAA composition notably differed between plasma and milk in dams. In milk, dietary L-Ser increased free L-Ser levels, while glutamic acid, L-alanine, D-alanine and taurine levels were decreased. The body weight of the offspring was lowered by dietary L-Ser. The concentrations of plasma FAAs in 13-day-old offspring (fed only milk) were not altered, but 20-day-old offspring (fed both milk and parental diet) showed higher plasma L-Ser and D-Ser concentrations as a result of the dietary L-Ser treatment. In conclusion, the present study found that dietary L-Ser transported easily from maternal plasma to milk and that dietary L-Ser treatment could change the FAA composition of milk, but that an enhanced level of L-Ser in milk did not enhance the plasma L-Ser level in the offspring.
DOI： 10.1292/jvms.17-0577
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L-Serine enhances light-induced circadian phase resetting in mice and humans Reviewed International journal
Shinobu Yasuo, Ayaka Iwamoto, Sang-il Lee, Shotaro Ochiai, Rina Hitachi, Satomi Shibata, Nobuo Uotsu, Chie Tarumizu, Sayuri Matsuoka, Mitsuhiro Furuse, Shigekazu Higuchi
Journal of Nutrition 147 ( 12 ) 2347 - 2355 2017.12
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約24時間のリズムを刻む概日時計（体内時計）は食事の時刻や内容により調節される。しかし、特定の栄養素が概日時計に及ぼす影響については不明な点が多い。本研究では、概日時計に影響を及ぼすアミノ酸を同定することを目的とした。
CBA/Nマウスにおいて、回転輪活動リズムの位相変化量を指標として解析を行った。20種類のアミノ酸のうち、L-セリンを投与したマウスでは、光による概日時計の位相変化が強まることが判明した。この効果はGABA-A受容体アンタゴニストであるピクロトキシンにより阻害された。また、明暗周期を6時間前進させてL-セリンを経口投与したところ、新しい明暗周期に対する再同調が早まった。
L-セリンの効果をヒトで実証するため、L-セリンが光による概日時計の位相前進に及ぼす影響について、男子大学生を対象として解析した。L-セリンを就寝前に摂取して翌朝に強い光を浴びると、概日時計の位相の指標であるメラトニン分泌開始時刻が有意に大きく前進した。
以上の結果から、光による概日時計のリセットがL-セリンの摂取により強まることが解明された。本成果により、概日時計の乱れや時差ぼけの改善にL-セリンが有用である可能性が示唆された。 -
Mao Nagasawa, Tsuyoshi Otsuka, Yuki Togo, Masakazu Yamanaga, Junki Yoshida, Nobuo Uotsu, Sachiyuki Teramoto, Shinobu Yasuo, Mitsuhiro Furuse
Amino Acids 49 ( 9 ) 1561 - 1570 2017.9
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In the present study, the effects of both single (6 mmol l-serine/10 ml/kg orally administrated) and chronic (2% l-serine solution freely given for 28 days) treatments on depression-like behavior were evaluated in Wistar rats, representing the control, and Wistar Kyoto rats, representing an animal model of depression. Both single and chronic l-serine treatments decreased the duration of immobility, which is an index of a depressive-like state, in the forced swimming test in both strains. However, the decreases in the duration of immobility appear to be regulated differently by the different mechanisms involved in single and chronic l-serine treatments. In the prefrontal cortex and hippocampus, single l-serine treatment increased the concentrations of l-serine, but not d-serine, while chronic l-serine treatment increased those of d-serine, but not l-serine. These data suggest that the antidepressant-like effects of single and chronic l-serine treatments may have been induced by the increased l-serine and d-serine concentrations, respectively, in the brain. In addition, chronic l-serine treatment increased cystathionine concentrations in the hippocampus and prefrontal cortex in Wistar rats, but not in Wistar Kyoto rats, suggesting that Wistar Kyoto rats have an abnormality in the serine–cystathionine metabolic pathway. In conclusion, single and chronic l-serine treatments may induce antidepressant-like effects via the different mechanisms related to serine metabolism in the brain.
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Takeshi Yamaguchi, Mao Nagasawa, Hiromi Ikeda, Momoko Kodaira, Kimie Minaminaka, Vishwajit S. Chowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Behavioural Brain Research 328 227 - 234 2017.6
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Attention-deficit hyperactivity disorder (ADHD) is defined as attention deficiency, restlessness and distraction. The main characteristics of ADHD are hyperactivity, impulsiveness and carelessness. There is a possibility that these abnormal behaviors, in particular hyperactivity, are derived from abnormal dopamine (DA) neurotransmission. To elucidate the mechanism of high locomotor activity, the relationship between innate activity levels and brain monoamines and amino acids was investigated in this study. Differences in locomotor activity between ICR, C57BL/6J and CBA/N mice were determined using the open field test. Among the three strains, ICR mice showed the greatest amount of locomotor activity. The level of striatal and cerebellar DA was lower in ICR mice than in C57BL/6J mice, while the level of L-tyrosine (L-Tyr), a DA precursor, was higher in ICR mice. These results suggest that the metabolic conversion of L-Tyr to DA is lower in ICR mice than it is in C57BL/6J mice. Next, the effects of intraperitoneal injection of (6R)-5, 6, 7, 8-tetrahydro-L-biopterin dihydrochloride (BH4) (a co-enzyme for tyrosine hydroxylase) and L-3,4-dihydroxyphenylalanine (L-DOPA) on DA metabolism and behavior in ICR mice were investigated. The DA level in the brain was increased by BH4 administration, but the increased DA did not influence behavior. However, L-DOPA administration drastically lowered locomotor activity and increased DA concentration in several parts of the brain. The reduced locomotor activity may have been a consequence of the overproduction of DA. In conclusion, the high level of locomotor activity in ICR mice may be explained by a strain-specific DA metabolism.
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Changes in photoperiod alter Glut4 expression in skeletal muscle of C57BL/6J mice Reviewed International journal
Ayako Tashiro, Satomi Shibata, Yusuke Takai, Tatsuhiro Uchiwa, Mitsuhiro Furuse, Shinobu Yasuo
Biochemical and Biophysical Research Communications 485 82 - 88 2017.3
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Momoko Kodaira, Mao Nagasawa, Takeshi Yamaguchi, Hiromi Ikeda, Kimie Minaminaka, Vishwajit S. Chowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Mechanisms of Ageing and Development 162 72 - 79 2017.3
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Aging and stress affect quality of life, and proper nourishment is one of means of preventing this effect. Today, there is a focus on the amount of protein consumed by elderly people; however, changes in the amino acid metabolism of individuals have not been fully considered. In addition, the difference between average life span and healthy life years is larger in females than it is in males. To prolong the healthy life years of females, in the present study we evaluated the influence of stress and aging on metabolism and emotional behavior by comparing young and middle-aged female mice. After 28 consecutive days of immobilization stress, behavioral tests were conducted and tissue sampling was performed. The results showed that the body weight of middle-aged mice was severely lowered by stress, but emotional behaviors were hardly influenced by either aging or stress. Aging influenced changes in amino acid metabolism in the brain and increased various amino acid levels in the uterus and ovary. In conclusion, we found that aged mice were more susceptible to stress in terms of body-weight reduction, and that amino acid metabolisms in the brain and genital organs were largely influenced by aging rather than by stress.
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Hiromi Ikeda, Mao Nagasawa, Takeshi Yamaguchi, Kimie Minaminaka, Ryosei Goda, Vishwajit S. Chowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Animal Science Journal 88 ( 3 ) 533 - 545 2017.3
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The Djungarian hamster and the Roborovskii hamster belong to the same genus of Phodopus. However, the Djungarian hamster is tame and shows sedative behavior, while Roborovskii hamster is not tame and shows high levels of locomotor activity. Hyperactivity occurs in animals with tameless behavior. Tameness or tamelessness behavior is very important because tameness helps for breeding and controlling as well as it enables a strong human-animal bond. In the present study, we examined the relationships between activity levels and cognitive function in Djungarian and Roborovskii hamsters. Three types of behavioral tests were performed to analyze their activity levels, memory and leaning ability. The levels of L- and D-amino acids and monoamines in the brain were then determined. Roborovskii hamsters showed significantly higher locomotor activity than Djungarian hamsters. Memory ability was not significantly different between the two hamsters, but Roborovskii hamsters showed lower learning ability. Brain levels of D-serine which is related to enhancement in memory and learning ability, were significantly higher in Djungarian hamsters, but the reverse was true for brain dopamine and serotonin levels. These results suggest that these differences in brain metabolism may be related to the behavioral differences between the two hamsters.
DOI： 10.1111/asj.12659
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Gut microbiota of mice putatively modifies amino acid metabolism in the host brain Reviewed
Takahiro Kawase, Mao Nagasawa, Hiromi Ikeda, Shinobu Yasuo, Yasuhiro Koga, Mitsuhiro Furuse
British Journal of Nutrition 117 ( 6 ) 775 - 783 2017.3
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Recently, it has been found that the gut microbiota influences functions of the host brain by affecting monoamine metabolism. The present study focused on the relationship between the gut microbiota and the brain amino acids. Specific pathogen-free (SPF) and germ-free (GF) mice were used as experimental models. Plasma and brain regions were sampled from mice at 7 and 16 weeks of age, and analysed for free d- and l-amino acids, which are believed to affect many physiological functions. At 7 weeks of age, plasma concentrations of d-aspartic acid (d-Asp), l-alanine (l-Ala), l-glutamine (l-Gln) and taurine were higher in SPF mice than in GF mice, but no differences were found at 16 weeks of age. Similar patterns were observed for the concentrations of l-Asp in striatum, cerebral cortex and hippocampus, and l-arginine (l-Arg), l-Ala and l-valine (l-Val) in striatum. In addition, the concentrations of l-Asp, d-Ala, l-histidine, l-isoleucine (l-Ile), l-leucine (l-Leu), l-phenylalanine and l-Val were significantly higher in plasma of SPF mice when compared with those of GF mice. The concentrations of l-Arg, l-Gln, l-Ile and l-Leu were significantly higher in SPF than in GF mice, but those of d-Asp, d-serine and l-serine were higher in some brain regions of GF mice than in those of SPF mice. In conclusion, the concentration of amino acids in the host brain seems to be dependent on presence of the gut microbiota. Amino acid metabolism in the host brain may be modified by manipulating microbiota communities.
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Takuma Nishigawa, Satsuki Nagamachi, Vishwajit S. Chowdhury, Shinobu Yasuo, Mitsuhiro Furuse
Biochemical and Biophysical Research Communications 2017.1
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Taurine, one of the sulfur-containing amino acids, has several functions in vivo. It has been reported that taurine acts on γ-aminobutyric acid receptors as an agonist and to promote inhibitory neurotransmission. Milk, especially colostrum, contains taurine and it is known that milk taurine is essential for the normal development of offspring. β-Alanine is transported via a taurine transporter and a protein-assisted amino acid transporter, the same ones that transport taurine. The present study aimed to investigate whether the growth and behavior of offspring could be altered by modification of the taurine concentration in milk. Pregnant ICR mice were separated into 3 groups: 1) a control group, 2) a taurine group, and 3) a β-alanine group. During the lactation periods, dams were administered, respectively, with 0.9% saline (10 ml/kg, i.p.), taurine dissolved in 0.9% saline (43 mg/10 ml/kg, i.p.), or β-alanine dissolved in 0.9% saline (31 mg/10 ml/kg, i.p.). Interestingly, the taurine concentration in milk was significantly decreased by the administration of β-alanine, but not altered by the taurine treatment. The body weight of offspring was significantly lower in the β-alanine group. β-Alanine treatment caused a significant decline in taurine concentration in the brains of offspring, and it was negatively correlated with total distance traveled in the open field test at postnatal day 15. Thus, decreased taurine concentration in the brain induced hyperactivity in offspring. These results suggested that milk taurine may have important role of regulating the growth and behavior of offspring.
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Exposure of C57BL/6J mice to long photoperiod during early life stages increases body weight and alters plasma metabolomic profiles in adulthood Reviewed International journal
Tatsuhiro Uchiwa, Yusuke Takai, Ayako Tashiro, Mitsuhiro Furuse, Yasuo Shinobu
Physiological Reports 4 e12974 2016.9
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Hericium erinaceus extracts alter behavioral rhythm in mice Reviewed International journal
Shoko Furuta, Rika Kuwahara, Eri Hiraki, Koichiro Ohnuki, Shinobu Yasuo, Kuniyoshi Shimizu
Biomedical Research 37 227-232 2016.3
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Dietary protein ingested before and during short photoperiods makes an impact on affect-related behaviours and plasma composition of amino acids in mice Reviewed International journal
Tsuyoshi Otsuka, Ryosei Goda, Ayaka Iwamoto, Misato Kawai, Satori Shibata, Yoshiaki Oka, Wataru Mizunoya, Mitsuhiro Furuse, Yasuo Shinobu
British Journal of Nutrition 114 1734 - 1743 2015.11
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Antidepressant-like effect of bright light is potentiated by L-serine administration in a mouse model of seasonal affective disorder Reviewed International journal
Misato Kawai, Ryosei Goda, Tsuyoshi Otsuka, Ayaka Iwamoto, Nobuo Uotsu, Mitsuhiro Furuse, Yasuo Shinobu
Brain Research Bulletin 118 25 - 33 2015.9
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Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder Reviewed International journal
Andras D. Nagy, Ayaka Iwamoto, Misato Kawai, Ryosei Goda, Haruka Matsuo, Tsuyoshi Otsuka, Mao Nagasawa, Mitsuhiro Furuse, Yasuo Shinobu
Chronobiology International 32 447 - 457 2015.5
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Serotonin levels in the dorsal raphe nuclei of both chipmunks and mice are enhanced by long photoperiod, but brain dopamine level response to photoperiod is species-specific Reviewed International journal
Ryosei Goda, Tsuyoshi Otsuka, Ayaka Iwamoto, Misato Kawai, Satomi Shibata, Mitsuhiro Furuse, Yasuo Shinobu
Neuroscience Letters ( 593 ) 95 - 100 2015.4
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Effects of time of l-ornithine administration on the diurnal rhythms of plasma growth hormone, melatonin, and corticosterone levels in mice Reviewed International journal
Haruka Matsuo, Ayaka Iwamoto, Tsuyoshi Otsuka, Yukihiro Hishida, Saori Akiduki, Mami Aoki, Shozo Tomonaga, Mitsuhiro Furuse, Yasuo Shinobu
Chronobiology International 32 225 - 234 2015.3
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2-Arachidonoyl glycerol sensitizes the pars distalis and enhances forskolin-stimulated prolactin secretion in Syrian hamsters Reviewed International journal
Yasuo Shinobu, Claudia Fischer, Joerg Bojunga, Masayuki Iigo, Horst-Werner Korf
Chronobiology International 31 337 - 342 2014.4
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Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice Reviewed International journal
Ayaka Iwamoto, Misato Kawai, Furuse Mitsuhiro, Yasuo Shinobu
Chronobiology International 31 189 - 198 2014.3
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Photoperiodic responses of depression-like behavior, the brain serotonergic system, and peripheral metabolism in laboratory mice Reviewed International journal
Tsuyoshi Otsuka, Misato Kawai, Yuki Togo, Ryosei Goda, Takahiro Kawase, Haruka Matsuo, Ayaka Iwamoto, Mao Nagasawa, Furuse Mitsuhiro, Yasuo Shinobu
Psychoneuroendocrinology 40 37 - 47 2014.2
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Melatonin-induced changes in the expression of thyroid hormone-converting enzymes in hypothalamus depend on the timing of melatonin injections and genetic background in mice. Reviewed International journal
Goto Mariko, Matsuo Haruka, Iigo Masayuki, Furuse Mitsuhiro, Horst-Werner Korf, Yasuo Shinobu
General and Comparative Endocrinology 186C 33 - 40 2013.3
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Photoperiod regulates dietary preferences and energy metabolism in young developing Fischer 344 rats but not in same-age Wistar rats Reviewed International journal
Togo Yuki, Otsuka Tsuyoshi, Goto Mariko, Furuse Mitsuhiro, Yasuo Shinobu
American Journal of Physiology-Endocrinology and Metabolism 303 ( 6 ) E777 - E786 2012.9
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Photoperiod regulates corticosterone rhythms by altered adrenal sensitivity via melatonin-independent mechanisms in Fischer 344 rats and C57BL/6J mice Reviewed International journal
Otsuka Tsuyoshi, Goto Mariko, Kawai Misato, Togo Yuki, Sato Katsuyoshi, Katoh Kazuo, Furuse Mitsuhiro, Yasuo Shinobu
PLoS ONE 7 ( 6 ) 2012.6
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Localization of an endocannabinoid system in the hypophysial pars tuberalis and pars distalis of man Reviewed International journal
Shinobu Yasuo, Claudia Unfried, Matthias Kettner, Gerd Geisslinger, Horst-Werner Korf
Cell and Tissue Research 2010.11
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An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes Reviewed International journal
Shinobu Yasuo, Marco Koch, Helmut Schmidt, Simone Ziebell, Joerg Bojung, Gerd Geisslinger, Horst-Werner Korf
Cell and Tissue Research 2010.4
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Photoperiodic control of TSH-b expression in the mammalian pars tuberalis has different impact on the induction and suppression of hypothalamo-hypophysial gonadal axis Reviewed International journal
Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
Journal of Neuroendocrinology 2010.1
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Involvement of thyrotropin in photoperiodic signal transduction in mice Reviewed International journal
Hiroko Ono, Hoshino Yuta, Shinobu Yasuo, Miwa Watanabe, Nakane Yusuke, Atsushi Murai, Shizufumi Ebihara, Horst-Werner Korf, Takashi Yoshimura
Proceedings of the National Academy of Sciences of the United States of America 2009.11
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Impact of melatonin and molecular clockwork components on the expression of thyrotropin-beta chain (Tshb) and the Tsh receptor in the mouse pars tuberalis Reviewed International journal
Claudia Unfried, Nariman Ansari, Shinobu Yasuo, Horst-Werner Korf, Charlotte von Gall
Endocrinology 2009.10
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Melatonin transmits photoperiodic signals through the MT1 melatonin receptor Reviewed International journal
Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
Journal of Neuroscience 2009.3
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Genetic and Molecular Analysis of wild-derived arrhythmic mice Reviewed International journal
Tsuyoshi Watanabe, Suzuki Tohru, Akira Ishikawa, Yuki Yokota, Hiroki R. Ueda, Rikuhiro G. Yamada, Hajime Tei, Saki Imai, Shigeru Tomida, Junya Kobayashi, Emiko Naito, Shinobu Yasuo, Nobuhiro Nakao, Takao Namikawa, Takashi Yoshimura, Shizufumi Ebihara
PLoS ONE 2009.1
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Rhythmic expression of clock genes in the ependymal cell layer of the third ventricle of rodents is independent of melatonin signaling Reviewed International journal
Shinobu Yasuo, Charlotte von Gall, David R Weaver, Horst-Werner Korf
European Journal of Neuroscience 2008.12
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Thyrotrophin in the pars tuberalis triggers photoperiodic response Reviewed International journal
Nobuhiro Nakao, Hiroko Ono, Takashi Yamamura, Tsubasa Anraku, Tsuyoshi Takagi, Kumiko Higashi, Shinobu Yasuo, Yasuhiro Katou, Saburo Kageyama, Yumiko Uno, Takeya Kasukawa, Masayuki Iigo, Peter J. Sharp, Atsushi Iwasawa, Yutaka Suzuki, Sumio Sugano, Teruyuki Niimi, Makoto Mizutani, Takao Namikawa, Shizufumi Ebihara, Hiroki R. Ueda, Takashi Yoshimura
Nature 2008.3
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Temporal dynamics of type 2 deiodinase expression after melatonin injections in Syrian hamsters Reviewed International journal
Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
Endocrinology 2007.9
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Photoperiodic changes in hypothalamic insulin receptor gene expression are regulated by gonadal testosterone Reviewed International journal
Tsubasa Anraku, Tsuyoshi Takagi, Nobuhiro Nakao, Miwa Watanabe, Shinobu Yasuo, Yasuhiro Katou, Yukihiro Ueda, Atsushi Murai, Masayuki Iigo, Shizufumi Ebihara, Takashi Yoshimura
Brain Research 2007.8
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Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in pre-ovulatory ovarian follicles Reviewed International journal
Nobuhiro Nakao, Shinobu Yasuo, Atsuko Nishimura, Takashi Yamamura, Tuyoshi Watanabe, Tubasa Anraku, Toshiyuki Okano, Yoshitaka Fukada, Peter J. Sharp, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2007.7
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Molecular evolution of prepro-thyrotropin-releasing hormone in the chicken (Gallus gallus) and its expression in the brain Reviewed International journal
Yasuhiro Aoki, Hiroko Ono, Shinobu Yasuo, Tomohiro Masuda, Takashi Yoshimura, Shizufumi Ebihara, Masayuki Iigo, Tadashi Yanagisawa
Zoological Science 2007.7
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Involvement of Transforming Growth Factor {alpha} in the Photoperiodic Regulation of Reproduction in Birds Reviewed International journal
Tsuyoshi Takagi, Takashi Yamamura, Tubasa Anraku, Shinobu Yasuo, Nobuhiro Nakao, Miwa Watanabe, Masayuki Iigo, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2007.6
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Differential response of type 2 deiodinase gene expression to photoperiod between photoperiodic Fischer 344 and nonphotoperiodic Wistar rats Reviewed International journal
Shinobu Yasuo, Miwa Watanabe, Masayuki Iigo, Takahiro J. Nakamura, Tsuyoshi Watanabe, Tsuyoshi Takagi, Hiroko Ono, Shizufumi Ebihara, Takashi Yoshimura
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2007.3
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Hypothalamic expression of thyroid hormone-activating and –inactivating enzyme genes in relation to photorefractoriness in birds and mammals Reviewed International journal
Tsuyoshi Watanabe, Takashi Yamamura, Miwa Watanabe, Shinobu Yasuo, Nobuhiro Nakao, Alistair Dawson, Shizufumi Ebihara, Takashi Yoshimura
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2007.1
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T3 implantation mimics photoperiodically reduced encasement of nerve terminals by glial processed in the median eminence of Japanese quail Reviewed International journal
Takahi Yamamura, Shinobu Yasuo, Kanjun Hirunagi, Shizufumi Ebihara, Takashi Yoshimura
Cell and Tissue Reserch 2006.4
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Peripheral clock gene expression in CS mice with bimodal locomotor rhythms Reviewed International journal
Tsuyoshi Watanabe, Hitomi Kojima, Shigeru Tomida, Takahiro J Nakamura, Nobuhiro Nakao, Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara
Neuroscience Research 2006.4
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Possible involvement of organic anion transporting polypeptide (Oatp) 1c1 in the photoperiodic response of gonads in birds Reviewed International journal
Nobuhiro Nakao, Tsuyoshi Takagi, Masayuki Iigo, Toshiro Tsukamoto, Shinobu Yasuo, Tomohiro Masuda, Tadashi Yanagisawa, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2006.3
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Long day suppressed expression of type 2 deiodinase gene in the mediobasal hypothalamus of the Saanen goat, a short day breeder: Implication for seasonal window of thyroid hormone action on reproductive neuroendocrine axis Reviewed International journal
Shinobu Yasuo, Nobuhiro Nakao, Satoshi Ohkura, Masayuki Iigo, Satoko Hagiwara, Akemitsu Goto, Hiroshi Ando, Takashi Yamamura, Miwa atanabe, Tsuyoshi Watanabe, Sen-ichi Oda, Kei-ichiro Maeda, Gerald Lincoln, Hiroaki Okamura, Shizuhumi Ebihara, Takashi Yoshimura
Endocrinology 2006.1
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Conservation of novel Mahya genes shows the existence of neural functions common between Hymenoptera and Deuterostome Reviewed International journal
Mayumi Tsuchimoto, Shinobu Yasuo, Masahiro Funada, Makoto Aoki, Hiromi Sasagawa, Sydney A. Cameron, Yasuo Kitagawa, Tatsuhiko Kadowaki
Development Genes and Evolution 215 ( 11 ) 564 - 574 2005.11
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The reciprocal switching of two thyroid hormone-activating and –inactivating enzyme genes is involved in the photoperiodic gonadal response of Japanese quail Reviewed International journal
Shinobu Yasuo, Miwa Watanabe, Nobuhiro Nakao, Tsuyoshi Takagi, Brian K. Follett, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2005.6
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Oral thyroxine administration mimics photoperiodically induced gonadal growth in Japanese quail Reviewed International journal
Shinobu Yasuo, Shizuhumi Ebihara, Takashi Yoshimura
Animal Science Journal 2004.10
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Photoperiodic regulation of type 2 deiodinase gene in Djungarian hamster: possible homologies between avian and mammalian photoperiodic regulation of reproduction Reviewed International journal
Miwa Watanabe, Shinobu Yasuo, Takashi Yamamura, Nobuhiro Nakao, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2004.4
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Circadian expression of clock gene in the optic tectum of Japanese quail Reviewed International journal
Shinobu Yasuo, Shizufumi Ebihara, Takashi Yoshimura
Brain Research 2004.4
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Characterization of the two distinct subtypes of metabotropic glutamate receptors from honeybee, Apis mellifera Reviewed International journal
Masahiro Funada, Shinobu Yasuo, Takashi Yoshimura,, Shizuhumi Ebihara, Hiromi Sasagawa, Yasuo Kitagawa, Tatsuhiko Kadowaki
Neuroscience Letters 2004.4
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Photoinducible phase specific light induction of Cry1 gene in the pars tuberalis of Japanese quail Reviewed International journal
Shinobu Yasuo, Miwa Watanabe, Akira Tsukada, Tsuyoshi Takagi, Kiyoshi Shimada, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2004.4
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Expression of IKKalpha mRNA in the suprachiasmatic nucleus and circadian rhythms of mice lacking IKKalpha Reviewed International journal
Noriko Hayashi, Shinobu Yasuo, Shizufumi Ebihara, Takashi Yoshimura
Brain Research 2003.12
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Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds Reviewed International journal
Takashi Yoshimura, Shinobu Yasuo, Miwa Watanabe, Masayuki Iigo, Takashi Yamamura, Kanjun Hirunagi, Shizufumi Ebihara
Nature 2003.11
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Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo Reviewed International journal
Naritoshi Okabayashi, Shinobu Yasuo, Miwa Watanabe, Takao Namikawa, Shizufumi Ebihara, Takashi Yoshimura
Brain Research 2003.11
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Circadian clock genes and photoperiodism: Comprehensive analysis of clock genes expression in the mediobasal hypothalamus, the suprachiasmatic nucleus and the pineal gland of Japanese quail under various light schedules Reviewed International journal
Shinobu Yasuo, Miwa Watanabe, Naritoshi Okabayashi, Shizufumi Ebihara, Takashi Yoshimura
Endocrinology 2003.9
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Language：English Publishing type：Research paper (scientific journal)
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Mapping quantitative trait loci affecting circadian photosensitivity in retinally degenerate mice Reviewed International journal
Takashi Yoshimura, Yuki Yokota, Akira Ishikawa, Shinobu Yasuo, Noriko Hayashi, Tohru Suzuki, Naritoshi Okabayashi, Takao Namikawa, Shizufumi Ebihara
Journal of Biological Rhythms 2002.12
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Language：English Publishing type：Research paper (scientific journal)
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Effect of melatonin administration on qPer2, qPer3, and qClock gene expression in the suprachiasmatic nucleus of Japanese quail Reviewed International journal
Shinobu Yasuo, Takashi Yoshimura, Paul A. Bartell, Masayuki Iigo, Eri Makino, Naritoshi Okabayashi, Shizufumi Ebihara
European Journal of Neuroscience 2002.10
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Language：English Publishing type：Research paper (scientific journal)
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Identification of the suprachiasmatic nucleus in birds Reviewed International journal
Takashi Yoshimura, Shinobu Yasuo, Yoshikazu Suzuki, Eri Makino, Yuki Yokota, Shizufumi Ebihara
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2001.4
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Language：English Publishing type：Research paper (scientific journal)
Books
Books
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JATAFFジャーナル 特集「時間栄養学の発展と最新知見」
安尾しのぶ（「食事リズムと認知機能および気分の関連」）
公益社団法人農林水産・食品産業技術振興協会 2024.10
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Internal desynchrony in mice under social jetlag-like conditions. Circadian Clocks, edited by K. Honma and S. Honma
Shinobu Yasuo, Saki Fukushima, Dan Yang, Daisuke Maji（Role：Joint author）
Hokkaido University Press,2023, Proceeding Volume for SSBR 2022 2023.9
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Language：English Book type：Scholarly book
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「アグリバイオ」臨時増刊号 肥満・メタボリックシンドロームと時間栄養学
安尾しのぶ（Role：Joint author）
北隆館 2020.7
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Responsible for pages：Vol.4(8), 13-17 Language：Japanese Book type：Scholarly book
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「時間栄養学」 第25章 季節性リズムと食・栄養
安尾しのぶ（Role：Joint author）
化学同人 2020.6
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Language：Japanese Book type：Scholarly book
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Chrononutritional modulation of sleep and the circadian clock by amino acids. In: Neurological Modulation of Sleep: Mechanisms and Functions in Sleep Health, Second Edition
Shinobu Yasuo（Role：Joint author）
Elsevier 2020.1
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Responsible for pages：375-383 Language：Japanese Book type：Scholarly book
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「食品機能性成分の吸収・代謝・作用機序」 第1章 アミノ酸「ストレス・睡眠関連アミノ酸」
古瀬充宏、安尾しのぶ（Role：Joint author）
シーエムシー出版 2018.4
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Language：Japanese Book type：Scholarly book
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「光周性の分子生物学」 12章 哺乳類の光周性と概年リズム: 3節 メラトニンと性腺活動の光周性
安尾しのぶ（Role：Joint author）
シュプリンガージャパン 2009.7
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Language：Japanese Book type：Scholarly book
Presentations
Presentations
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乱れやすい体内時計を整えるための時間栄養学・時間生薬学の取り組み Invited
安尾しのぶ
第44回日本看護科学学会学術集会 2024.12
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Event date： 2024.12
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
Venue：熊本城ホール Country：Japan
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周期的な環境エンリッチメントによるマウスの情動・認知行動変化メカニズムの解析
黒木海斗、馬天天、篠塚まりな、森田竜未、宮本舜佑、洲崎礼紀、谷口楓果、岩佐菜月美、石村公花、松尾涼平、池上啓介、安尾しのぶ
第31回日本時間生物学会学術大会 2024.11
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Event date： 2024.11
Language：Japanese Presentation type：Poster presentation
Venue：富山国際会議場 Country：Japan
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胎児期や生後初期の光環境によるエピジェネティック制御機構〜げっ歯類・家畜モデルを用いたアプローチ〜 Invited
安尾しのぶ
第12回新胎児学研究会（ 2024.11
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Event date： 2024.11
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：九州大学 Country：Japan
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哺乳期の日長に対するマウスの脳部位・末梢組織特異的な応答性
松尾涼平、石村公花、岩佐菜月美、黒木海斗、池上啓介、安尾しのぶ
第31回日本時間生物学会学術大会 2024.11
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Event date： 2024.11
Language：Japanese Presentation type：Poster presentation
Venue：富山国際会議場 Country：Japan
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哺乳期の日長によるウシ骨格筋のエピジェネティック制御
松尾涼平、塚谷春香、黒木海斗、後藤貴文、池上啓介、安尾しのぶ
日本畜産学会第132回大会 2024.9
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Event date： 2024.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：京都大学 Country：Japan
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哺乳期の日長が脳および末梢臓器に及ぼす長期的影響の解析
石村 公花、岩佐 菜月美、黒木 海斗、松尾 涼平、池上 啓介、安尾 しのぶ
日本畜産学会第132回大会 2024.9
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Event date： 2024.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：京都大学 Country：Japan
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初期成長期の光環境による代謝プログラミングとエピジェネティック制御機構
安尾しのぶ
日本畜産学会第132回大会 2024.9
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Event date： 2024.9
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：京都大学 Country：Japan
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ダルスの飲水投与が活動リズムおよび認知機能に及ぼす影響
宮本 舜佑、篠塚 まりな、谷口 楓果、森田 竜未、池上 啓介、熊谷 祐也、岸村 栄毅、中熊 大英、池口 主弥、安尾 しのぶ
第11回日本時間栄養学会学術大会 2024.8
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Event date： 2024.8
Language：Japanese Presentation type：Poster presentation
Venue：東京工業大学 Country：Japan
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Weekly Environmental Enrichment Alters Affective and Cognitive Behaviors and Hippocampal Gene Expression Profiles in Mice International conference
Kaito Kurogi, Ma Tiantian, Marina Shinozuka, Tatsumi Morita, Shunsuke Miyamoto, Raiki Suzaki, Fuka Taniguchi, Natsumi Iwasa, Kimika Ishimura, Ryohei Matsuo, Keisuke Ikegami, Shinobu Yasuo
International Chronobiology Summer School 2024 2024.8
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Event date： 2024.8
Language：English Presentation type：Poster presentation
Venue：名古屋大学 Country：Japan
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Sex-dependent effects of chronic jet lag on circadian rhythm and metabolism in mice International conference
Tiantian Ma, Marina Shinozuka, Shunsuke Miyamoto, Morita Tatsumi, Fuka Taniguchi, Keisuke Ikegami, Shinobu Yasuo
Sapporo Symposium on Biological Rhythms 2024 2024.8
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Event date： 2024.8
Language：English Presentation type：Poster presentation
Venue：北海道大学 Country：Japan
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Effect of early-life photoperiod on body weight gain in mice and epigenetic regulation of skeletal muscle in cows International conference
Ryohei Matsuo, Haruka Tsukatani, Kaito Kurogi, Keisuke Ikegami, Shinobu Yasuo
Sapporo Symposium on Biological Rhythms 2024 2024.8
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Event date： 2024.8
Language：English Presentation type：Poster presentation
Venue：北海道大学 Country：Japan
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Impact of early-life photoperiod on development and epigenetic mechanisms in mammals Invited International conference
Shinobu Yasuo
Asian Forum on Chronobiology 2024 2024.8
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Event date： 2024.8
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：北海道大学 Country：Japan
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概日時計の内的脱同調を改善するための生薬の探索
森田竜未、馬天天、黒木海斗、池上啓介、大賀勇人、佐藤岳、間地大輔、安尾しのぶ
第11回日本時間栄養学会学術大会 2024.8
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Event date： 2024.8
Language：Japanese Presentation type：Poster presentation
Venue：東京工業大学 Country：Japan
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光環境のかく乱による概日時計および代謝機能の性依存的な変調 Invited
安尾しのぶ
第51回日本毒性学会学術年会 2024.7
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Event date： 2024.7
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：福岡市国際会館 Country：Japan
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社会的時差ぼけ様条件下における概日時計の内的脱同調およびその改善に向けた生薬の探索
安尾しのぶ、福島早記、森田竜未、大賀勇人、佐藤岳、間地大輔
第24回日本抗加齢医学会総会 2024.6
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Event date： 2024.6
Language：Japanese Presentation type：Poster presentation
Venue： 熊本城ホール（熊本県熊本市） Country：Japan
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慢性的な明暗シフトが概日時計および代謝に及ぼす影響の性差 Invited
安尾しのぶ
第101回日本生理学会大会 2024.3
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Event date： 2024.3
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：北九州市 Country：Japan
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食事リズムと脳機能の関係から導く現代社会の健康増進 Invited
安尾しのぶ
第63回日本心身医学会九州地方会 2024.1
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Event date： 2024.1
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：福岡市, 中村学園大学 Country：Japan
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Sex-dependent effect of chronic jet lag on circadian clock and metabolism Invited International conference
Shinobu Yasuo and Tiantian Ma
China-Japan Chronobiology Summit Forum in 2023 2023.12
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Event date： 2023.12
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：Northwest A&F University Country：China
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初期成長期の日長による脳神経発達および増体の調節
松尾涼平、黒木海斗、安尾しのぶ
日本発達神経科学会第12回学術集会 2023.11
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Event date： 2023.11
Language：Japanese Presentation type：Poster presentation
Venue：福岡市、九州大学 Country：Japan
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L-オルニチンの経口投与による成長ホルモン分泌促進の機序解析
黒木 海斗、松尾 涼平、洲崎 礼紀、谷口 栄望、服部 歩実、菱田 幸宏、渡邊 史子、古瀬 充宏、安尾 しのぶ
日本アミノ酸学会第17回学術大会 2023.10
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Event date： 2023.10
Language：Japanese Presentation type：Symposium, workshop panel (public)
Venue：福岡市 西新プラザ Country：Japan
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Sex-dependent effects of chronic jetlag on circadian clock and metabolism in mice
Tiantian Ma, Marina Shinozuka, Fuka Taniguchi, Shunsuke Miyamoto, Keisuke Ikegami, Shinobu Yasuo
日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会合同大会 2023.9
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Event date： 2023.9
Language：English Presentation type：Poster presentation
Venue：横浜市, パシフィコ横浜 Country：Japan
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慢性的な時差環境における概日時計および代謝の乱れの性差
馬天天、篠塚まりな、谷口楓果、宮本舜佑、池上啓介、安尾しのぶ
第10回日本時間栄養学会学術大会 2023.8
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Event date： 2023.8
Language：Japanese Presentation type：Poster presentation
Venue：広島市, 広島大学 Country：Japan
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周期的な環境エンリッチメントによる時間ストレス学的研究
洲崎礼紀、福島早記、黒木海斗、松尾涼平、丸山創平、篠塚まりな、青木一生、吉岡真理子、住本夏美、安尾しのぶ
第10回日本時間栄養学会学術大会 2023.8
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Event date： 2023.8
Language：Japanese Presentation type：Poster presentation
Venue：広島市, 広島大学 Country：Japan
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周期的な環境エンリッチメントが生体に及ぼす影響の系統差および性差
谷口楓果、吉岡真理子、黒木海斗、洲崎礼紀、篠塚まりな、安尾しのぶ
第10回日本時間栄養学会学術大会 2023.8
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Event date： 2023.8
Language：Japanese Presentation type：Poster presentation
Venue：広島市, 広島大学 Country：Japan
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Seasonal adaptation of growth, muscle, and brain via early-life photoperiod Invited
Shinobu Yasuo
第100回日本生理学会大会 2023.3
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Event date： 2023.3
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：京都市, 国立京都国際会館 Country：Japan
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漸進的な日長の延長によるマウスの増体促進および哺乳期の日長によるウシ骨格筋のエピジェネティック制御
松尾涼平、黒木海斗、丸山創平、Dan Yang、Viet Phuong Tran、高井優生、大嶋雄治、後藤貴文、安尾しのぶ
第29回日本時間生物学会学術大会 2022.12
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Event date： 2022.12
Language：Japanese Presentation type：Poster presentation
Venue：栃木県宇都宮市, 宇都宮大学 Country：Japan
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食のタイミングと脳機能：機能性成分による体内時計の保護へ向けて
安尾しのぶ
第29回日本時間生物学会学術大会 2022.12
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Event date： 2022.12
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：栃木県宇都宮市, 宇都宮大学 Country：Japan
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周期的な住環境変化に対する行動解析および脳内遺伝子応答の網羅的解析
黒木海斗、松尾涼平、洲崎礼紀、篠塚まりな、谷口楓果、高井優生、大嶋雄治、安尾 しのぶ
第29回日本時間生物学会学術大会 2022.12
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Event date： 2022.12
Language：Japanese Presentation type：Poster presentation
Venue：栃木県宇都宮市, 宇都宮大学 Country：Japan
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夜型給餌リズム下の記憶低下に対する大豆イソフラボンの改善効果および海馬の各種遺伝子発現に対する影響
丸山創平、黒木海斗、松尾涼平、青木一生、篠塚まりな、安尾しのぶ
第29回日本時間生物学会学術大会 2022.12
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Event date： 2022.12
Language：Japanese Presentation type：Poster presentation
Venue：栃木県宇都宮市, 宇都宮大学 Country：Japan
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周期的な住環境変化に対する脳内遺伝子応答の網羅解析
黒木海斗 、松尾涼平、洲崎礼紀、篠塚 まりな、谷口楓果、高井優生、大嶋雄治、安尾しのぶ
日本畜産学会第130回大会 2022.9
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Event date： 2022.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学およびオンライン Country：Japan
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哺乳期の日長によるマウスの増体促進メカニズムおよびウシ骨格筋のエピジェネティック制御
松尾涼平、黒木海斗、丸山創平、Dan Yang、Viet Phuong Tran、高井優生、大嶋雄治、後藤貴文、安尾しのぶ
日本畜産学会第130回大会 2022.9
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Event date： 2022.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学およびオンライン Country：Japan
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哺乳期の日長によるマウスの増体促進メカニズムおよびウシ骨格筋のエピジェネティック制御
松尾涼平、黒木海斗、丸山創平、Dan Yang、Viet Phuong Tran、高井優生、大嶋雄治、後藤貴文、安尾しのぶ
第9回日本時間栄養学会学術大会 2022.8
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Event date： 2022.8
Language：Japanese Presentation type：Poster presentation
Venue：福岡市, グローカルホテル糸島 Country：Japan
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Internal desynchrony in mice under social jetlag-like condition Invited International conference
Shinobu Yasuo, Saki Fukushima, Dan Yang, Hiroko Miyazaki, Daisuke Maji
Sapporo Symposium on Biological Rhythm in 2022 2022.8
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Event date： 2022.8
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：札幌市, 北海道大学 Country：Japan
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オルニチンによる成長ホルモン分泌促進機序の解析
黒木海斗、松尾涼平、洲崎礼紀、谷口 栄望、服部歩実、菱田幸宏、渡邊史子、古瀬充宏、安尾しのぶ
第9回日本時間栄養学会学術大会 2022.8
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Event date： 2022.8
Language：Japanese Presentation type：Poster presentation
Venue：福岡市, グローカルホテル糸島 Country：Japan
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夜型給餌リズム下の記憶低下に対する大豆イソフラボンの改善効果
丸山創平、黒木海斗、松尾涼平、青木一生、篠塚まりな、安尾しのぶ
第9回日本時間栄養学会学術大会 2022.8
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Event date： 2022.8
Language：Japanese Presentation type：Poster presentation
Venue：福岡市, グローカルホテル糸島 Country：Japan
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脳機能と時間栄養学
安尾しのぶ
第76回日本栄養・食糧学会大会 2022.6
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Event date： 2022.6
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：兵庫県神戸市 Country：Japan
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食事リズムによる体内時計調節とアンチエイジング Invited
安尾しのぶ
第4回日本抗加齢医学会 九州地方会学術総会 2022.2
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Event date： 2022.2
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：福岡県福岡市 Country：Japan
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Spermidine resets circadian clock phase in vitro
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
第28回日本時間生物学会学術大会 2021.11
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Event date： 2021.11
Language：English Presentation type：Poster presentation
Venue：沖縄県那覇市 Country：Japan
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社会的時差ぼけ様条件下の中高齢マウスにおける概日時計の内的脱同調
福島早記、大坪駿、柴田健児、黒木海斗、宮﨑裕子、間地大輔、古瀬充宏、安尾しのぶ
第28回日本時間生物学会学術大会 2021.11
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Event date： 2021.11
Language：Japanese Presentation type：Poster presentation
Venue：沖縄県那覇市 Country：Japan
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Establishment of cellular jet lag model and identification of spermidine as a potent modulator of circadian clock phase in NIH3T3 cells
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
第8回日本時間栄養学会学術大会 2021.8
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Event date： 2021.8
Language：English Presentation type：Poster presentation
Venue：オンライン Country：Japan
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Establishment of cellular jet lag model and search for nutrients that modulate circadian phase International conference
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
5th Asian Forum on Chronobiology 2021.7
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Event date： 2021.7
Language：English Presentation type：Symposium, workshop panel (public)
Venue：オンライン Country：Japan
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体内時計と環境リズムの関係から切り拓くアンチエイジングの可能性 Invited
安尾しのぶ、福島早記、Dan Yang、宮崎裕子、間地大輔
第21回日本抗加齢医学会総会 2021.6
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Event date： 2021.6
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
Venue：京都、オンライン Country：Japan
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Interaction effect of regular and irregular stimulation cycles of dexamethasone and insulin on circadian clock in NIH3T3 cells
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
第27回日本時間生物学会学術大会 2020.9
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Event date： 2020.9
Language：Japanese Presentation type：Poster presentation
Venue：オンライン Country：Japan
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明暗周期の乱れや週サイクルの環境エンリッチメントが中高齢マウスに及ぼす影響
福島早記、Dan Yang、谷口栄望、服部歩実、宮﨑裕子、間地大輔、古瀬充宏、安尾しのぶ
第27回日本時間生物学会学術大会 2020.9
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Event date： 2020.9
Language：Japanese Presentation type：Poster presentation
Venue：オンライン Country：Japan
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時間制限給餌による恒明条件下の短期記憶低下の改善
大坪駿、柴田健児、福島早記、古瀬充宏、安尾しのぶ
第7回 日本時間栄養学会学術大会 2020.8
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Event date： 2020.8
Language：Japanese Presentation type：Symposium, workshop panel (public)
Venue：オンライン Country：Japan
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Chrononutritional modulation of the circadian clock by amino acids Invited International conference
Shinobu Yasuo
The 7th International Conference of Food Factors 2019.12
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Event date： 2019.12
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：神戸 Country：Japan
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Entrainment of the circadian clock of NIH3T3 cells to stimulation cycle: in vitro model for jet lag
Dan Yang, Hideaki Oike, Mitsuhiro Furuse, Shinobu Yasuo
第26回 日本時間生物学会学術大会 2019.10
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Event date： 2019.10
Language：Japanese Presentation type：Poster presentation
Venue：金沢 Country：Japan
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L-セリンと光による協調的な遺伝子発現調節の網羅解析
安尾しのぶ、谷口栄望、服部歩実、田代絢子、古瀬充宏
日本アミノ酸学会第13回学術大会 2019.10
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Event date： 2019.10
Language：Japanese Presentation type：Oral presentation (general)
Venue：岩手大学 Country：Japan
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摂食時刻の違いがマウスの各種行動や海馬の神経可塑性関連因子に及ぼす影響
大坪駿、菊竹鴻太、服部歩実、谷口栄望、古瀬充宏、安尾しのぶ
第26回 日本時間生物学会学術大会 2019.10
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Event date： 2019.10
Language：Japanese Presentation type：Poster presentation
Venue：金沢 Country：Japan
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大学生における食事習慣と精神的健康および性格との関連
服部歩実、古田和敬、大坪駿、柴田健児、古瀬充宏、安尾しのぶ
第26回 日本時間生物学会学術大会 2019.10
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Event date： 2019.10
Language：Japanese Presentation type：Poster presentation
Venue：金沢 Country：Japan
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自然日長シミュレーションを用いた情動行動や遺伝子発現の季節変動解析
柴田健児、大坪駿、谷口栄望、服部歩実、古瀬充宏、安尾しのぶ
日本畜産学会第126回大会 2019.9
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Event date： 2019.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：岩手大学 Country：Japan
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摂食時刻の違いが情動・記憶・学習や海馬の時計遺伝子発現に及ぼす影響
安尾しのぶ、菊竹鴻太、大坪駿、古田和敬、古瀬充宏
第73回日本栄養・食糧学会大会 2019.5
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Event date： 2019.5
Language：Japanese Presentation type：Oral presentation (general)
Venue：静岡県立大学 Country：Japan
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生体の季節リズムを利用した 代謝プログラミングの畜産応用 Invited
安尾しのぶ
日本農芸化学会2019年度大会 2019.3
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Event date： 2019.3
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：東京農業大学 Country：Japan
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日長による神経新生の調節
#谷口栄望、#高木望、#刀根享大、#服部歩実、古瀬充宏、安尾しのぶ
第25回 日本時間生物学会学術大会 2018.10
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Event date： 2018.10
Language：Japanese Presentation type：Poster presentation
Venue：長崎大学 Country：Japan
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発達期の日長によるDNAメチル化酵素の発現調節
#高木望、古瀬充宏、安尾しのぶ
第25回 日本時間生物学会学術大会 2018.10
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Event date： 2018.10
Language：Japanese Presentation type：Poster presentation
Venue：長崎大学 Country：Japan
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アミノ酸による体内時計の調整：マウスからヒトへの応用展開 Invited
安尾しのぶ
第60回歯科基礎医学会学術大会 2018.9
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Event date： 2018.9
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：九州大学 Country：Japan
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食事リズムが情動行動や記憶・学習行動に及ぼす影響
安尾しのぶ、#菊竹鴻太、#大坪駿
第5回 時間栄養科学研究会 2018.8
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Event date： 2018.8
Language：Japanese Presentation type：Symposium, workshop panel (public)
Venue：女子栄養大学 Country：Japan
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Early-life photoperiod alters affective behaviors, memory and learning, and hippocampal morphology International conference
Yasuo S, #Tone Y, #Takai Y, #Kawai M, #Takaki M
Asian Forum of Chronobiology 2018 2018.7
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Event date： 2018.7
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：Sapporo Convention Center Country：Japan
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Effect of early-life photoperiod on affective behaviors, memory and learning, neurogenesis, and neuronal development
Yasuo S, #Tone Y, #Takai Y, #Kawai M, #Takaki M, Furuse M
第41 回日本神経科学大会 2018.7
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Event date： 2018.7
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：神戸コンベンションセンター Country：Japan
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哺乳期の日長が黒毛和種の成長や骨格筋関連指標に及ぼす影響
安尾しのぶ、打和龍宏、高木望、古閑弘晃、志賀灯、高橋秀之、後藤貴文、古瀬充宏
日本畜産学会第124回大会 2018.3
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Event date： 2018.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京大学 Country：Japan
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発達期における神経新生の光周性はNitric oxide系により制御される
高木望、高井佑輔、古瀬充宏、安尾しのぶ
第24回 日本時間生物学会学術大会 2017.10
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Event date： 2017.10
Language：Japanese Presentation type：Poster presentation
Venue：京都大学 Country：Japan
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哺乳期までの長日飼育は記憶・学習能力を高める
刀根享大、打和龍宏、菊竹鴻太、高木望、古瀬充宏、安尾しのぶ
第24回 日本時間生物学会学術大会 2017.10
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Event date： 2017.10
Language：Japanese Presentation type：Poster presentation
Venue：京都大学 Country：Japan
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哺乳期の日長を利用した代謝プログラミングの試み
打和龍宏、高木望、古閑弘晃、志賀灯、高橋秀之、後藤貴文、古瀬充宏、安尾しのぶ
第24回 日本時間生物学会学術大会 2017.10
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Event date： 2017.10
Language：Japanese Presentation type：Poster presentation
Venue：京都大学 Country：Japan
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哺乳期の日長による代謝プログラミング：畜産への応用に向けた試み
安尾しのぶ、打和龍宏、高木望、古閑弘晃、後藤貴文
第4回時間栄養科学研究会／第12回ニュートリズム検討会 2017.8
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Event date： 2017.8
Language：Japanese Presentation type：Symposium, workshop panel (public)
Venue：名古屋大学 Country：Japan
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動物の季節リズム研究における応用と代替法の可能性 Invited
安尾 しのぶ, 田代 絢子, 高井 佑輔
第29回日本動物実験代替法学会 2016.11
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Event date： 2016.11
Language：Japanese Presentation type：Oral presentation (general)
Venue：九州大学医学部 Country：Japan
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うつ様行動の光周性反応に及ぼす骨格筋グルココルチコイド受容体の影響
田代 絢子, 高井 佑輔, 打和 龍宏, 清水 宣明, 田中 廣壽, 古瀬 充宏, 安尾 しのぶ
第23回日本時間生物学会学術大会 2016.11
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Event date： 2016.11
Language：Japanese Presentation type：Poster presentation
Venue：名古屋大学 Country：Japan
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哺乳期の日長は成熟後の体重や代謝に影響を与える
打和 龍宏, 高井 佑輔, 田代 絢子, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第23回日本時間生物学会学術大会 2016.11
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Event date： 2016.11
Language：Japanese Presentation type：Poster presentation
Venue：名古屋大学 Country：Japan
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オルニチンの時間栄養学〜ホルモンリズム調節の観点から〜 Invited
安尾 しのぶ
第2回シトルリン・オルニチン研究懇談会 2016.9
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Event date： 2016.9
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：大手町サンスカイルーム Country：Japan
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体内時計の調節因子としてのアミノ酸および香り成分 Invited
安尾 しのぶ
第14回果実酒・果実飲料と健康に関する研究会 2016.9
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Event date： 2016.9
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：和歌山医科大学 Country：Japan
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うつ様行動の光周性における骨格筋グルココルチコイド受容体の役割
田代 絢子, 高井 佑輔, 打和 龍宏, 清水 宣明, 田中 廣壽, 古瀬 充宏, 安尾 しのぶ
第3回時間栄養科学研究会 2016.8
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Event date： 2016.8
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学 Country：Japan
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The role of skeletal muscle glucocorticoid receptors in photoperiodic response of depression-like behaviors International conference
Ayako Tashiro, Ryosei Goda, Satomi Shibata, Yusuke Takai, Tsuyoshi Otsuka, Tatsuhiro Uchiwa, Mitsuhiro Furuse, Shinobu Yasuo
17th AAAP Animal Science Congress 2016.8
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Event date： 2016.8
Language：English Presentation type：Oral presentation (general)
Venue：Kyushu Sangyo University Country：Japan
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Effect of postnatal photoperiod on body weight and metabolomics profiles in skeletal muscle and plasma in mice International conference
Tatsuhiro Uchiwa, Yusuke Takai, Ayako Tashiro, Satomi Shibata, Mitsuhiro Furuse, Shinobu Yasuo
17th AAAP Animal Science Congress 2016.8
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Event date： 2016.8
Language：English Presentation type：Oral presentation (general)
Venue：Kyushu Sangyo University Country：Japan
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Effect of photoperiod during perinatal period on neurogenesis and stress-related behaviors in mice International conference
Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasuo
17th AAAP Animal Science Congress 2016.8
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Event date： 2016.8
Language：English Presentation type：Oral presentation (general)
Venue：Kyushu Sangyo University Country：Japan
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哺乳期の日長は成熟後のマウスの体重や血漿・骨格筋メタボロームに影響を及ぼす
打和 龍宏, 高井 佑輔, 田代 絢子, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第3回時間栄養科学研究会 2016.8
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Event date： 2016.8
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学 Country：Japan
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アミノ酸栄養による体内時計の調節とヒトへの応用展開 Invited
安尾 しのぶ, 樋口 重和, 魚津 伸夫, 垂水 千恵, 雄長 誠
第70回栄養・食料学会大会 2016.5
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Event date： 2016.5
Language：Japanese Presentation type：Symposium, workshop panel (public)
Venue：武庫川女子大学 Country：Japan
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Effect of perinatal photoperiod on neurogenesis and affective behaviors in mice International conference
Yusuke Takai, Misato Kawai, Tadashi Ogo, Takashi Ichinose, Shigeki Furuya, Hiroshi Udo, Mitsuhiro Furuse, Shinobu Yasuo
64th NIBB Conference "Evolution of Seasonal Timers" 2016.4
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Event date： 2016.4
Language：English Presentation type：Symposium, workshop panel (public)
Venue：岡﨑コンファレンスセンター Country：Japan
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幼若期における短日条件がマウスの神経新生・分化に及ぼす影響
高井 佑輔, 池田 裕美, 有働 洋, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第121回大会 2016.3
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Event date： 2016.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：日本獣医生命科学大学 Country：Japan
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若齢期の日長がマウスの成長や代謝に及ぼす影響
打和 龍宏, 高井 佑輔, 田代 絢子, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第121回大会 2016.3
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Event date： 2016.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：日本獣医生命科学大学 Country：Japan
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動物モデルを用いた季節性感情障害の解析と改善法の探索 Invited
安尾 しのぶ
第18回日本補完代替医療学会学術集会 2015.11
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Event date： 2015.11
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：石川県文教会館 Country：Japan
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情動の光周性における骨格筋グルココルチコイド受容体の役割
田代 絢子, 五田 亮世, 柴田 里美, 高井 佑輔, 大塚 剛司, 古瀬 充宏, 安尾 しのぶ
第21回日本時間生物学会学術大会 2015.11
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Event date： 2015.11
Language：Japanese Presentation type：Poster presentation
Venue：東京大学 Country：Japan
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初期成長期における日長が情動行動や神経新生に及ぼす影響
高井 佑輔, 河井 美里, 市瀬 嵩志, 古屋 茂樹, 有働 洋, 古瀬 充宏, 安尾 しのぶ
第21回日本時間生物学会学術大会 2015.11
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Event date： 2015.11
Language：Japanese Presentation type：Poster presentation
Venue：東京大学 Country：Japan
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幼若期の日長は情動行動・神経新生・脳内遊離アミノ酸組成に影響を及ぼす
高井 佑輔, 河井 美里, 小河 匡, 池田 裕美, 市瀬 嵩志, 古屋 茂樹, 有働 洋, 古瀬 充宏, 安尾 しのぶ
日本アミノ酸学会第9回学術大会 2015.10
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Event date： 2015.10
Language：Japanese Presentation type：Poster presentation
Venue：滋賀県立大学 Country：Japan
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骨格筋におけるグルココルチコイド関連遺伝子やグルコース輸送体の発現に及ぼす日長の影響
田代 絢子, 柴田 里美, 高井 佑輔, 大塚 剛司, 五田 亮世, 古瀬 充宏, 安尾 しのぶ
第2回時間栄養科学研究会 2015.9
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Event date： 2015.9
Language：Japanese Presentation type：Poster presentation
Venue：早稲田大学 Country：Japan
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Photoperiodic responsiveness of depression-like behavior and the brain serotonergic system in mice. International conference
Tsuyoshi Otsuka, Ayaka Iwamoto, Misato Kawai, Takahiro Kawase, Ryosei Goda, Mitsuhiro Furuse, Shinobu Yasuo
2014 Meeting of the Society for Research on Biological Rhythms 2015.6
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Event date： 2015.6
Language：English Presentation type：Symposium, workshop panel (public)
Venue：Big Sky (Montana) Country：United States
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Affect-related behaviors and plasma composition of amino acids in mice under short day were modified by dietary proteins. International conference
Tsuyoshi Otsuka, Ryosei Goda, Ayaka Iwamoto, Misato Kawai, Satori Shibata, Yoshiaki Oka, Wataru Mizunoya, Mitsuhiro Furuse, Shinobu Yasuo
The 12th Asian Congress of Nutrition 2015.5
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Event date： 2015.5
Language：English Presentation type：Symposium, workshop panel (public)
Venue：Yokohama Country：Japan
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うつ様行動や筋分解関連遺伝子発現の光習性に及ぼす副腎摘出の影響
五田 亮世, 柴田 里美, 高井 佑輔, 田代 絢子, 大塚 剛司, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第119回大会 2015.3
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Event date： 2015.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：宇都宮大学 Country：Japan
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初期成長期における日長の違いが情動行動や神経新生に与える影響
高井 佑輔, 河井 美里, 小河 匡, 市瀬 嵩志, 古屋 茂樹, 有働 洋, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第119回大会 2015.3
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Event date： 2015.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：宇都宮大学 Country：Japan
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骨格筋におけるグルココルチコイド関連遺伝子やグルコース輸送体の発現に及ぼす日長の影響
田代 絢子, 柴田 里美, 大塚 剛司, 五田 亮世, 高井 佑輔, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第119回大会 2015.3
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Event date： 2015.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：宇都宮大学 Country：Japan
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情動の季節リズムと脳−末梢連関 Invited
安尾 しのぶ
第120回日本解剖学会・第92回日本生理学会 合同大会 2015.3
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Event date： 2015.3
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：神戸国際会議場・展示場 Country：Japan
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アミノ酸栄養と体内時計 Invited
安尾 しのぶ
第1回時間栄養科学研究会 2015.2
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Event date： 2015.2
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：早稲田大学 Country：Japan
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概日時計調節アミノ酸の探索とリズム関連疾患への応用
安尾 しのぶ
第21回日本時間生物学会学術大会 2014.11
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Event date： 2014.11
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：九州大学医学部（福岡） Country：Japan
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Effects of L-serine Intake on Light-induced Circadian Phase Advance in Human
落合 将太郎, 松森 考平, 李 相逸, 垂水 千恵, 魚津 伸夫, 安尾 しのぶ, 樋口 重和
第21回日本時間生物学会学術大会 2014.11
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Event date： 2014.11
Language：Japanese Presentation type：Poster presentation
Venue：九州大学医学部（福岡） Country：Japan
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副腎除去は情動行動および筋代謝の光周性を阻害する
五田 亮世, 大塚 剛司, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第21回日本時間生物学会学術大会 2014.11
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Event date： 2014.11
Language：Japanese Presentation type：Poster presentation
Venue：九州大学医学部（福岡） Country：Japan
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慢性的時差ぼけ処理がCBA/Nマウスの概日時計および情動行動に及ぼす影響
柴田 里美, 岩本 綾香, 古瀬 充宏, 安尾 しのぶ
第21回日本時間生物学会学術大会 2014.11
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Event date： 2014.11
Language：Japanese Presentation type：Poster presentation
Venue：九州大学医学部（福岡） Country：Japan
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短日条件におけるマウスの情動関連行動の栄養学的制御
大塚 剛司, 岩本 綾香, 河井 美里, 五田 亮世, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第16回ペット栄養学会 2014.7
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Event date： 2014.7
Language：Japanese Presentation type：Oral presentation (general)
Venue：日本獣医生命科学大学 Country：Japan
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概日時計調節機能をもつアミノ酸の同定と機能解析
安尾 しのぶ, 岩本 綾香, 河井 美里, 山崎 いづみ, 古瀬 充宏
第68回日本栄養・食糧学会大会 2014.5
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Event date： 2014.5 - 2014.6
Language：Japanese Presentation type：Oral presentation (general)
Venue：酪農学園大学 Country：Japan
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短日条件におけるマウスの情動関連行動を制御できる食餌タンパク質の探索
大塚 剛司, 岩本 綾香, 河井 美里, 五田 亮世, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第118回日本畜産学会 2014.3
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Event date： 2014.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：つくば国際会議場 Country：Japan
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高照度光および L-セリンが短日条件におけるマウスのうつ様行動に及ぼす影響
河井 美里, 大塚 剛司, 山崎 いづみ, 古瀬 充宏, 安尾 しのぶ
第20回日本時間生物学会学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：近畿大学 Country：Japan
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昼行性シマリスの脳内モノアミン含量に及ぼす日長の影響
五田 亮世, 大塚 剛司, 岩本 綾香, 河井 美里, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第20回日本時間生物学会学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：近畿大学 Country：Japan
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様々な食餌タンパク質が短日条件におけるマウスの情動関連行動に及ぼす影響
大塚 剛司, 岩本 綾香, 河井 美里, 五田 亮世, 柴田 里美, 古瀬 充宏, 安尾 しのぶ
第20回日本時間生物学会学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：近畿大学 Country：Japan
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概日時計を調節できるアミノ酸の探索：L-セリンによる光応答性の増強
岩本 綾香, 山崎 いづみ, 古瀬 充宏, 安尾 しのぶ
第20回日本時間生物学会学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：近畿大学 Country：Japan
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L-セリンは光による概日時計のリセットを強化する
岩本 綾香, 山崎 いづみ, 古瀬 充宏, 安尾 しのぶ
日本アミノ酸学会第7回学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：熊本市医師会館 Country：Japan
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短日条件における高照度光の抗うつ様効果とL-セリンによる増強
河井 美里, 大塚 剛司, 山崎 いづみ, 古瀬 充宏, 安尾 しのぶ
日本アミノ酸学会第7回学術大会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Poster presentation
Venue：熊本市医師会館 Country：Japan
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概日時計を調節する機能性食品因子の解析 Invited
安尾 しのぶ
第21回「食と健康」講演会 2013.11
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Event date： 2013.11
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：東京 Country：Japan
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Photoperiodic responses of the brain serotonergic system and mood-related behaviors in mammals Invited International conference
Shinobu Yasuo, Tsuyoshi Otsuka, Misato Kawai, Mitsuhiro Furuse
12th Congress of the European Biological Rhythms Society 2013.8
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Event date： 2013.8
Language：English Presentation type：Symposium, workshop panel (public)
Venue：Munich Country：Germany
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Effects of photoperiod on depression-like behaviors, brain serotonergic system, and glucose tolerance in mice International conference
Tsuyoshi Otsuka, Ayaka Iwamoto, Misato Kawai, Takahiro Kawase, Ryosei Goda, Mitsuhiro Furuse, Shinobu Yasuo
12th Congress of the European Biological Rhythms Society 2013.8
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Event date： 2013.8
Language：English Presentation type：Poster presentation
Venue：Munich Country：Germany
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光条件変化がマウスの糖耐性およびスクロース嗜好性に及ぼす影響
大塚 剛司, 岩本 綾香, 川瀬 貴博, 五田 亮世, 河井 美里, 古瀬 充宏, 安尾 しのぶ
第15回ペット栄養学会 2013.7
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Event date： 2013.7
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京大学 Country：Japan
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Pathophysiological analysis of seasonal affective disorder using an animal model: photoperiodic regulation in serotonergic system and metabolism Invited International conference
Shinobu Yasuo
Neuro2013 2013.6
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Event date： 2013.6
Language：English Presentation type：Symposium, workshop panel (nominated)
Venue：Kyoto International Conference Center, Kyoto Country：Japan
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マウスのセロトニン神経系、糖耐性およびスクロース嗜好性は光条件に調節される
大塚 剛司, 松尾 陽香, 岩本 綾香, 河井 美里, 五田亮世, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第116回大会 2013.3
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Event date： 2013.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：安田女子大学（広島） Country：Japan
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日長と照度がマウスの活動および深部体温リズムに及ぼす影響
五田 亮世, 岩本 綾香, 岡本 剛, 古瀬 充宏, 安尾 しのぶ
日本畜産学会第116回大会 2013.3
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Event date： 2013.3
Language：Japanese Presentation type：Oral presentation (general)
Venue：安田女子大学（広島） Country：Japan
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モデル動物を用いた冬季うつ病の病態解析と治療に向けた試み Invited
安尾 しのぶ
第86回日本薬理学会年会 2013.3
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Event date： 2013.3
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：福岡国際会議場（福岡） Country：Japan
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冬季うつ病の動物モデルを用いた病態解析：神経行動から代謝特性まで Invited
安尾 しのぶ
第8回NutriRhythm検討会 2012.12
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Event date： 2012.12
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：東京国際フォーラム（東京） Country：Japan
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日長がFischer 344ラットの血漿遊離アミノ酸濃度に及ぼす影響
河井 美里, 大塚 剛司, 長澤 麻央, 古瀬 充宏, 安尾 しのぶ
第5回暖地畜産学会 2012.11
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Event date： 2012.11
Language：Japanese Presentation type：Oral presentation (general)
Venue：九州大学（福岡） Country：Japan
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概日時計に影響を及ぼすアミノ酸の探索
岩本 綾香, 河井 美里, 松尾 陽香, 古瀬 充宏, 安尾 しのぶ
日本アミノ酸学会第6回学術大会 2012.9
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Event date： 2012.9
Language：Japanese Presentation type：Poster presentation
Venue：千葉大学園芸学部（千葉） Country：Japan
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L-オルニチンの投与時刻依存的なホルモン分泌リズム制御
松尾 陽香, 岩本 綾香, 大塚 剛司, 秋月 さおり, 青木 麻実, 古瀬 充宏, 安尾 しのぶ
日本アミノ酸学会第6回学術大会 2012.9
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Event date： 2012.9
Language：Japanese Presentation type：Poster presentation
Venue：千葉大学園芸学部（千葉） Country：Japan
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日長と照度の組み合わせがマウスの情動行動および糖代謝に及ぼす影響
大塚 剛司, 松尾 陽香, 岩本 綾香, 河井 美里, 五田亮世, 古瀬 充宏, 安尾 しのぶ
第19回日本時間生物学会学術大会 2012.9
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Event date： 2012.9
Language：Japanese Presentation type：Poster presentation
Venue：北海道大学（札幌） Country：Japan
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季節性感情障害のモデル動物についての可能性を探る
安尾 しのぶ, 大塚 剛司, 河井 美里
第19回日本時間生物学会学術大会 2012.9
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Event date： 2012.9
Language：Japanese Presentation type：Poster presentation
Venue：北海道大学（札幌） Country：Japan
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季節の生体リズムと食 Invited
安尾 しのぶ
睡眠学会第37回学術集会 2012.6
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Event date： 2012.6
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：パシフィコ横浜（横浜） Country：Japan
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マウスにおける情動行動の光周性反応
大塚剛司、都合勇希、友永省三、長澤麻央、後藤真梨子、古瀬充宏、安尾しのぶ
第115回日本畜産学会 2012.3
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Event date： 2012.3
Presentation type：Oral presentation (general)
Venue：名古屋 Country：Japan
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L-リジン欠乏が哺乳類の概日時計機構に及ぼす影響
松尾陽香、後藤真梨子、古瀬充宏、安尾しのぶ
第115回日本畜産学会 2012.3
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Event date： 2012.3
Presentation type：Oral presentation (general)
Venue：名古屋 Country：Japan
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Senstizing effects of 2-arachidonoylglycerol in hypophysis and hypothalamus of mammals International conference
Yasuo S, Unfried C, Bojunga J, Iigo M, Otsuka T, Togo Y, Schreiber Y, Geisslinger G, Korf HW
107th Annual Meeting of Anatomische Gesellshaft 2012.3
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Event date： 2012.3
Presentation type：Oral presentation (general)
Venue：Frankfurt am Main Country：Germany
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アミノ酸栄養と概日時計 Invited
安尾 しのぶ
第6回栄養改善学会若手の会冬期シンポジウム 2011.12
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Event date： 2011.12
Presentation type：Oral presentation (general)
Venue：福岡 Country：Japan
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季節性感情障害の病態モデル動物の開発と解析
安尾 しのぶ
第18回日本時間生物学会学術大会 2011.11
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Event date： 2011.11
Presentation type：Oral presentation (general)
Venue：名古屋 Country：Japan
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日長が季節繁殖性および周年繁殖性のラットの栄養選択性に及ぼす影響
都合 勇希、大塚 剛司、後藤 真梨子、古瀬 充宏、安尾 しのぶ
第18回日本時間生物学会学術大会 2011.11
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Event date： 2011.11
Presentation type：Poster presentation
Venue：名古屋 Country：Japan
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哺乳類の糖質コルチコイド分泌を制御する光周性制御機構
後藤真梨子、大塚剛司、河井美里、都合勇希、佐藤勝祥、加藤和雄、古瀬充宏、安尾しのぶ
第18回日本時間生物学会学術大会 2011.11
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Event date： 2011.11
Presentation type：Poster presentation
Venue：名古屋 Country：Japan
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マウスを用いた情動の光周性反応の解析
大塚剛司、都合勇希、後藤真梨子、長澤麻央、友永省三、古瀬充宏、安尾しのぶ
第18回日本時間生物学会学術大会 2011.11
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Event date： 2011.11
Presentation type：Poster presentation
Venue：名古屋 Country：Japan
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L-リジン欠乏がマウスの概日時計に及ぼす影響
松尾陽香，後藤真梨子，古瀬充宏，安尾しのぶ
日本アミノ酸学会第5回学術大会 2011.11
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Event date： 2011.11
Presentation type：Poster presentation
Venue：名古屋 Country：Japan
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光周性の分子神経内分泌と季節栄養学
安尾しのぶ
家畜栄養生理研究会秋季集談会 2011.10
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Event date： 2011.10
Presentation type：Symposium, workshop panel (nominated)
Venue：仙台 Country：Japan
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Melatonin transmits the photoperiodic signals through MT1 receptor International conference
Yasuo S, Yoshimura T, Ebihara S, Korf HW
Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference “Melatonin Receptors: Actions and Therapeutic” 2011.6
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Event date： 2011.6 - 2011.7
Presentation type：Symposium, workshop panel (nominated)
Venue：Snowmass Village, CO Country：United States
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日長がFischer 344 ラットの不安行動に及ぼす影響
大塚剛司、都合勇希、古瀬充宏、安尾しのぶ
第17回 日本時間生物学会 2010.11
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Event date： 2010.11
Presentation type：Poster presentation
Venue：東京 Country：Japan
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Multiple messengers from the hypophysial pars tuberalis: their functions and signaling pathways Invited International conference
Shinobu Yasuo
25th Conference of European Comparative Endocrinologists 2010.9
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Event date： 2010.8 - 2010.9
Presentation type：Symposium, workshop panel (nominated)
Venue：Pecs Country：Hungary
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哺乳類の下垂体隆起葉におけるエンドカンナビノイドシステムとプロラクチン分泌の光周性制御機構
安尾しのぶ、Marco Koch、Helmut Schmidt、Simone Ziebell、Gerd Geisslinger、Horst-Werner Korf
第112回日本畜産学会 2010.3
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Event date： 2010.3
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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Identification of endocannabinoid in the hypophysial pars tuberalis of the Syrian hamster: its possible role for seasonal prolactin secretion Invited International conference
Shinobu Yasuo, Marco Koch, Simone Zeibell, Helmut Schmidt, Gerd Geisslinger, Horst-Werner Korf
11th Congress of the European Biological Rhythms Society 2009.8
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Event date： 2009.8
Presentation type：Oral presentation (invited, special)
Venue：Strasbourg Country：France
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Delayed response of thyrotropin-beta subunit gene to melatonin in the pars tuberalis of Syrian hamsters International conference
Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
11th Congress of the European Biological Rhythms Society 2009.8
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Event date： 2009.8
Presentation type：Poster presentation
Venue：Strasbourg Country：France
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Identification of endocannabinoid in the hypophysial pars tuberalis of the Syrian hamster, a photoperiodic species International conference
Shinobu Yasuo, Marco Koch, Simone Zeibell, Helmut Schmidt, Gerd Geisslinger, Horst-Werner Korf
104th Annual Meeting of the Anatomische Gesellschaft 2009.3
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Event date： 2009.3
Presentation type：Oral presentation (general)
Venue：Antwerp Country：Belgium
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Expression of Faah in the ependymal cell layer of the infundibular recess is regulated by the photoperiod International conference
Shinobu Yasuo, Horst-Werner Korf
Leopoldina Symposium on Lipid Signaling 2008.9
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Event date： 2008.9
Presentation type：Symposium, workshop panel (nominated)
Venue：Frankfurt am Main Country：Germany
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Expression of fatty acid amide hydrolase in the ependymal cell layer of the infundibular recess depends on the photoperiod International conference
Shinobu Yasuo, Horst-Werner Korf
25. Arbeitstagung der Anatomischen Gesellschaft 2008.9
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Event date： 2008.9
Presentation type：Oral presentation (general)
Venue：Wurzburg Country：Germany
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Rhythmic expression of clock genes in the ependymal cell layer of the third ventricle: possible role for the photoperiodic response of gonads in mammals International conference
Shinobu Yasuo, Charlotte von Gall, Elmar Christ, Horst-Werner Korf
103rd Annual Meeting of the Anatomische Gesellschaft 2008.3
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Event date： 2008.3
Presentation type：Oral presentation (general)
Venue：Innsbruck Country：Austria
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Identification of the melatonin receptor subtype involved in the photoperiodic response in mammals International conference
Shinobu Yasuo, Horst-Werner Korf
24. Arbeitstagung der Anatomischen Gesellschaft 2007.9
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Event date： 2007.9
Presentation type：Symposium, workshop panel (nominated)
Venue：Wurzburg Country：Germany
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Effects of melatonin injections on type 2 deiodinase mRNA levels in the mediobasal hypothalamus of male golden hamsters International conference
Shinobu Yasuo, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
102nd Annual Meeting of the Anatomische Gesellschaft 2007.4
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Event date： 2007.4
Presentation type：Oral presentation (general)
Venue：Giessen Country：Germany
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ハムスターにおける光周性制御機構：メラトニンによるtype2 deiodinaseの発現調節
安尾しのぶ、海老原史樹文、吉村崇、Horst-Werner Korf
第13回時間生物学会 2006.11
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Event date： 2006.11
Presentation type：Symposium, workshop panel (nominated)
Venue：東京 Country：Japan
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Reciprocal switching of type 2 and type 3 deiodinase genes is involved in the photoperiodic gonadal response of Japanese quail International conference
Shinobu Yasuo, Miwa Watanabe, nobuhiro nakao, Tsuyoshi Takagi, Shizufumi Ebihara, Takashi Yoshimura
24th International Ornithological Congress 2006.8
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Event date： 2006.8
Presentation type：Symposium, workshop panel (public)
Venue：Hamburg Country：Germany
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Melatonin suppress type 2 deiodinase mRNA levels in the mediobasal hypothalamus of male golden hamsters already one day after the onset of treatment International conference
Shinobu Yasuo, Nariman Ansari, Qian Zhang, Takashi Yoshimura, Shizufumi Ebihara, Horst-Werner Korf
23rd Conference of European Comparative Endocrinologists 2006.8
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Event date： 2006.8
Presentation type：Oral presentation (general)
Venue：Manchester Country：United Kingdom
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Long-day suppressed expression of type 2 deiodinase in the mediobasal hypothalamus of the Saanen goat, a short-day breeder International conference
Shinobu Yasuo, Nobuhiro Nakao, Satoshi Ohkura, Masayuki Iigo, Sen-ichi Oda, Kei-ichiro Maeda, Takashi Yamamura, Miwa Watanabe, Tsuyoshi Watanabe, Gerald Lincoln, Hiroaki Okamura, Shizufumi Ebihara, Takashi Yoshimura
10th meeting of Society for Research on Biological Rhythms 2006.5
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Event date： 2006.5
Presentation type：Poster presentation
Venue：Sandestin FL Country：United States
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ヤギの季節繁殖の制御機構
安尾しのぶ、中尾暢宏、大蔵聡、飯郷雅之、織田銑一、前多敬一郎、山村崇、渡邊美和、渡辺剛史、岡村裕昭、海老原史樹文、吉村崇
第106回日本畜産学会 2006.3
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Event date： 2006.3
Presentation type：Oral presentation (general)
Venue：福岡 Country：Japan
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短日繁殖動物における光周性制御機構：ヤギ（日本ザーネン種）におけるType 2 deiodinaseの発現
安尾しのぶ、中尾暢宏、大蔵聡、飯郷雅之、織田銑一、前多敬一郎、山村崇、渡邊美和、渡辺剛史、岡村裕昭、海老原史樹文、吉村崇
第12回時間生物学会 2005.11
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Event date： 2005.11
Presentation type：Symposium, workshop panel (public)
Venue：つくば Country：Japan
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Fine tuning of photoperiodic time information in avian brain Invited International conference
Shinobu Yasuo, Miwa Watanabe, Masayuki Iigo, Takashi amamura, Nobuhiro Nakao, Tsuyoshi Takagi, Shizufumi Ebihara, Takashi Yoshimura
10th Congress of the European Pineal and Biological Rhythms Society 2005.9
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Event date： 2005.9
Presentation type：Oral presentation (general)
Venue：Frankfurt am Main Country：Germany
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季節繁殖性と周年繁殖性の制御機構：ラットにおけるtype 2 deiodinaseの発現
安尾しのぶ、渡邊美和、中村孝博、渡邊剛史、海老原史樹文、吉村崇
第104回日本畜産学会 2005.3
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Event date： 2005.3
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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季節繁殖性および周年繁殖性のラットにおけるType 2 deiodinaseの発現
安尾しのぶ、渡邊美和、中村孝博、渡辺剛史、海老原史樹文、吉村崇
第10回時間生物学会 2004.11
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Event date： 2004.11
Presentation type：Poster presentation
Venue：滋賀 Country：Japan
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Photoperiodic regulation of phase relationship between Per2 and Cry1 genes expression in the pars tuberalis of Japanese quail International conference
Shinobu Yasuo, Miwa Watanabe, Akira Tsukada, Kiyoshi Shimada, Shizufumi Ebihara, and Takashi Yoshimura
9th meeting of Society for Research on Biological Rhythms 2004.6
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Event date： 2004.6
Presentation type：Poster presentation
Venue：Whistler BC Country：Canada
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Clock genes and photoperiodism in Japanese quail International conference
Shinobu Yasuo, Miwa Watanabe, Akira Tsukada, Kiyoshi Shimada, Shizufumi Ebihara, and Takashi Yoshimura
8th International Symposium on Avian Endocrinology 2004.6
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Event date： 2004.6
Presentation type：Poster presentation
Venue：Scottsdale AR Country：United States
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鳥類の時計遺伝子と光周性
安尾しのぶ、渡邊美和、塚田光、島田清司、海老原史樹文、吉村崇
第103回日本畜産学会 2004.3
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Event date： 2004.3
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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鳥類の時計遺伝子と光周性
安尾しのぶ、吉村崇、岡林生才、渡邊美和、海老原史樹文
第9回時間生物学会 2003.11
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Event date： 2003.11
Presentation type：Poster presentation
Venue：名古屋 Country：Japan
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Clock genes and photoperiodism in Japanese quail International conference
Shinobu Yasuo, Miwa Watanabe, Naritoshi Okabayashi, Shizufumi Ebihara, and Takashi Yoshimura
1st Worrd Congress of Chronobiology 2003.9
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Event date： 2003.9
Presentation type：Poster presentation
Venue：Sapporo Country：Japan
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鳥類の光周性の分子機構I：時計遺伝子と光周性
安尾しのぶ、岡林生才、渡邊美和、海老原史樹文、吉村崇
第101回日本畜産学会 2003.3
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Event date： 2003.3
Presentation type：Oral presentation (general)
Venue：つくば Country：Japan
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Effect of melatonin administration on expression of clock genes in the suprachiasmatic nucleus of Japanese quail International conference
Shinobu Yasuo, Takashi Yoshimura, Paul Bartell, Masayuki Iigo, Eri Makino, Naritoshi Okabayashi, Shizufumi Ebihara.
8th meeting of Society for Research on Biological Rhythms 2002.5
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Event date： 2002.5
Presentation type：Poster presentation
Venue：Jacksonville FL Country：United States
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ウズラ視交叉上核(SCN)における時計遺伝子の発現とメラトニンの影響
安尾しのぶ、吉村崇、牧野江里、Paul Bartell、岡林生才、飯郷雅之、海老原史樹文
第100回日本畜産学会 2002.3
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Event date： 2002.3
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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ウズラの卵巣には時計が存在する
安尾しのぶ、岡林生才、海老原史樹文、吉村崇
第100回日本畜産学会 2002.3
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Event date： 2002.3
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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卵巣における時計遺伝子の発現
安尾しのぶ、吉村崇、岡林生才、海老原史樹文
第8回時間生物学会 2001.11
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Event date： 2001.11
Presentation type：Poster presentation
Venue：山口 Country：Japan
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Effects of melatonin on clock genes expression of the SCN in Japanese quail International conference
Shinobu Yasuo, Takashi Yoshimura, Paul Bartell, Masayuki Iigo, Eri Makino, Naritoshi Okabayashi, Shizufumi Ebihara.
International Symposium on Molecular Clock Kobe-Awaji 2001.9
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Event date： 2001.9
Presentation type：Poster presentation
Venue：Kobe Country：Japan
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鳥類の視交叉上核(SCN)に対するメラトニンの影響
安尾しのぶ、吉村崇、牧野江里、横田祐樹、飯郷雅之、Paul Bartell、海老原史樹文
第98回日本畜産学会 2001.3
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Event date： 2001.3
Presentation type：Oral presentation (general)
Venue：仙台 Country：Japan
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鳥類視交叉上核(SCN)の特性
安尾しのぶ、吉村崇、横田祐樹、牧野江里、飯郷雅之、Paul Bartell、海老原史樹文
第7回日本時間生物学会 2000.11
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Event date： 2000.11
Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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鳥類の視交叉上核(SCN)の同定
安尾しのぶ、吉村崇、鈴木喜和、横田祐樹、牧野江里、海老原史樹文
第97回日本畜産学会 2000.3
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Event date： 2000.3
Presentation type：Oral presentation (general)
Venue：京都 Country：Japan
MISC
MISC
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概日時計の乱れの性差と時間栄養学 Invited
安尾しのぶ
日本農学アカデミー会報 第42号 2024.12
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共創的な生体リズム研究拠点を目指して
安尾しのぶ
日本時間生物学会誌 2024.11
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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時間栄養学はストレス社会にどのように貢献できるか
谷口楓果、洲崎礼紀、安尾しのぶ
時間栄養学研究の最前線 2024.3
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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時間栄養学における動物実験代替法の可能性
Yang Dan, 福島早記, 洲崎礼記, 安尾しのぶ
時間栄養学研究の最前線 2021.6
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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光周性の分子神経内分泌と季節栄養学
安尾しのぶ、都合勇希、大塚剛司、後藤真梨子、古瀬充宏
家畜栄養生理研究会 2011.10
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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動物における光周性の分子・神経内分泌基盤
安尾しのぶ
日本時間生物学会会誌 2011.6
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Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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The hypophysial pars tuberalis transduces photoperiodic signals via multiple pathways and messenger molecules
Shinobu Yasuo, Horst-Werner Korf
General and Comparative Endocrinology 2011.5
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Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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The hypophysial pars tuberalis transduces photoperiodic signals via multiple pathways and messenger molecules
Yasuo Shinobu, Horst-Werner Korf
Gen Comp Endocrinol 2011.3
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Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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下垂体隆起葉における光周性シグナル分子
安尾しのぶ、Horst-Werner Korf
日本時間生物学会誌 2010.5
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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Comparative analysis of the molecular basis of the photoperiodism
Shinobu Yasuo, Takashi Yoshimura
Integrative and Comparative Biology, 49 (5), 507-518 2009.5
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Language：English
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Molecular mechanism of photoperiodic time measurement in the brain of Japanese quail
Shinobu Yasuo, Miwa Watanabe, Masayuki Iigo, Takashi Yamamura, Nobuhiro Nakao, Tsuyoshi Takagi, Shizufumi Ebihara, Takashi Yoshimura
Choronobiology International 23, 307-315 2006.1
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Language：English
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Photoperiodic time measurement
Takashi Yoshimura, Shinobu Yasuo, Takashi Yamamura, Nobuhiro Nakao, Shizufumi Ebihara
Functional Avian Endocrinology. A Dawson & PJ Sharp Eds, Narosa Publishing House, New Delhi, India, pp141-150 2005.1
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Language：English
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脊椎動物の光周性
中尾暢宏、安尾しのぶ、山村崇、海老原史樹文、吉村崇
比較生理学会誌 22(1), 20-26 2005.1
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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脊椎動物における光周性の制御機構
海老原史樹文、安尾しのぶ、吉村崇
生物物理 45(4), 185-191 2005.1
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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生物はいかにして季節を読み取っているか？
山村崇、安尾しのぶ、中尾暢宏、海老原史樹文、吉村崇
化学と生物 43(3)172-176 2005.1
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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Melatonin regulation of clock genes in birds
Shizufumi Ebihara, Shinobu Yasuo, Takashi Yoshimura
Functional Avian Endocrinology. A Dawson & PJ Sharp Eds, Narosa Publishing House, New Delhi, India, pp215-222 2005.1
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Language：English
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鳥類の時計遺伝子と光周性
安尾しのぶ、渡邊美和、海老原史樹文、吉村崇
時間生物学会誌 10(1), 135-40 2004.1
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Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
Professional Memberships
Professional Memberships
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Japanese Society for Anti-aging Medicine
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Japan Chrono-Nutrition Society
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日本時間栄養学会
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Warm Regional Society of Animal Science, Japan
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Japanese Society of Animal Science
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The Japanese Society for Amino Acid Sciences
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Japanese Society for Chronobiology
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Japan Society of Nutrition and Food Science
Committee Memberships
Committee Memberships
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日本学術会議 畜産学分科会 Organizer Domestic
2023.10 - 2029.9
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日本学術会議 IUNS分科会 連携会員 Domestic
2023.10 - 2029.9
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日本学術会議 連携会員 Domestic
2023.10 - 2029.9
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日本学術会議 畜産学分科会 連携会員、幹事 Domestic
2023.10 - 2029.9
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日本学術会議 生物リズム分科会 連携会員 Domestic
2023.10 - 2029.9
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日本時間栄養学会 Vice-chairman Domestic
2023.1 - 2028.12
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日本時間生物学会 Executive Domestic
2023.1 - 2025.12
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日本暖地畜産学会 編集委員 Domestic
2017.10 - 2019.9
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日本時間栄養学会 幹事 Domestic
2014.10 - 2025.3
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日本畜産学会 若手奨励・男女共同参画推進委員会委員 Domestic
2013.6 - 2015.3
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日本時間生物学会 Councilor Domestic
2010.2 - 2025.3
Academic Activities
Academic Activities
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第11回日本時間栄養学会学術大会 シンポジウム座長
Role(s)： Panel moderator, session chair, etc.
2024.8
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Type：Competition, symposium, etc.
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第14回家畜感染症学会シンポジウム・総会 大会長
第14回家畜感染症学会シンポジウム・総会 （ Japan ） 2024.6
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Type：Competition, symposium, etc.
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第78 回日本栄養・食糧学会大会シンポジウムオーガナイザー
Role(s)： Planning, management, etc.
2024.5
More details
Type：Competition, symposium, etc.
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第78 回日本栄養・食糧学会大会プログラム委員
Role(s)： Planning, management, etc.
2024.5
More details
Type：Competition, symposium, etc.
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日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会 合同大会 副大会長、プログラム委員会委員
日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会 合同大会 （ Japan ） 2023.9
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Type：Competition, symposium, etc.
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Screening of academic papers
Role(s)： Peer review
2023
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Type：Peer review
Number of peer-reviewed articles in foreign language journals：5
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優秀発表賞選考委員会委員
第9回日本時間栄養学会学術大会 （ Japan ） 2022.8
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Type：Competition, symposium, etc.
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第9回日本時間栄養学会学術大会 大会長
第9回日本時間栄養学会学術大会 （ Japan ） 2022.8
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Type：Competition, symposium, etc.
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Screening of academic papers
Role(s)： Peer review
2022
More details
Type：Peer review
Number of peer-reviewed articles in foreign language journals：10
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組織委員会委員、プログラム委員会委員
第28回日本時間生物学会学術大会 （ Japan ） 2021.11 - Present
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Type：Competition, symposium, etc.
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実行委員会委員
第14回日本暖地畜産学会大会 （ Japan ） 2021.10
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Type：Competition, symposium, etc.
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優秀発表賞選考委員会委員長
第8回日本時間栄養学会学術大会 （ Japan ） 2021.8
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Type：Competition, symposium, etc.
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日本畜産学会機関誌 Animal Science Journal
2021.4 - 2025.4
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Type：Academic society, research group, etc.
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日本畜産学会機関誌 Animal Science Journal
2021.4 - 2023.4
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Type：Academic society, research group, etc.
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実行委員会委員
第128回日本畜産学会大会 （ Japan ） 2021.3
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Type：Competition, symposium, etc.
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Screening of academic papers
Role(s)： Peer review
2021
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Type：Peer review
Number of peer-reviewed articles in foreign language journals：6
Number of peer-reviewed articles in Japanese journals：1
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座長
第27回日本時間生物学会学術大会 （ Japan ） 2020.9
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Type：Competition, symposium, etc.
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プログラム委員会委員
第27回日本時間生物学会学術大会 （ Japan ） 2020.9
More details
Type：Competition, symposium, etc.
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Screening of academic papers
Role(s)： Peer review
2020
More details
Type：Peer review
Number of peer-reviewed articles in foreign language journals：3
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Screening of academic papers
Role(s)： Peer review
2019
More details
Type：Peer review
Number of peer-reviewed articles in foreign language journals：4
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Screening of academic papers
Role(s)： Peer review
2018
More details
Type：Peer review
Number of peer-reviewed articles in foreign language journals：8
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日本暖地畜産学会報
2017.10 - 2019.9
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Type：Academic society, research group, etc.
-
Screening of academic papers
Role(s)： Peer review
2017
More details
Type：Peer review
Number of peer-reviewed articles in foreign language journals：9
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大会組織準備委員会委員 International contribution
17th Asian-Australasian Association of Animal Production Societies (AAAP) Animal Science Congres （ Japan ） 2016.8
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Type：Competition, symposium, etc.
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座長（Chairmanship）
第116回日本畜産学会 （ Japan ） 2013.3
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Type：Competition, symposium, etc.
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座長（Chairmanship）
第115回日本畜産学会 （ Japan ） 2012.3
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Type：Competition, symposium, etc.
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座長（Chairmanship）
第112回日本畜産学会 （ Japan ） 2010.3
More details
Type：Competition, symposium, etc.
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日本学術会議 生物リズム分科会主催 公開シンポジウム 「睡眠・冬眠と体内時計 〜生物リズムの進化から未来社会を考える〜」座長
Role(s)： Panel moderator, session chair, etc.
More details
Type：Competition, symposium, etc.
Research Projects
Research Projects
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代謝刷り込み型牛放牧肥育技術の高度化事業
2025.4 - 2028.3
日本中央競馬会畜産振興事業
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Authorship：Coinvestigator(s) Grant type：Contract research
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マルチスケールリズムの相互作用に伴う性依存的な生体変調機序の統合理解と予測技術への応用
2024.10 - 2030.3
日本医療研究開発機構 革新的先端研究開発支援事業 AMED-CREST
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Authorship：Principal investigator Grant type：Contract research
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次世代和牛生産システム構築拠点
2024.10 - 2026.3
JST共創の場形成支援プログラム
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Authorship：Coinvestigator(s) Grant type：Contract research
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負の情動改善を伴う我が国に適した採卵鶏飼育法の構築
2022 - 2023
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
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Authorship：Coinvestigator(s) Grant type：Scientific research funding
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周期的環境を利用した新しいストレスバイオロジーの開拓
2021.4 - 2028.3
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Authorship：Principal investigator
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周期的環境を利用した新しいストレスバイオロジーの開拓
2021 - 2025.3
創発的研究支援事業
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Authorship：Principal investigator Grant type：Contract research
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代謝刷り込みによる牛放牧肥育技術開発事業
2021 - 2023
日本中央競馬会畜産振興事業
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Authorship：Coinvestigator(s) Grant type：Contract research
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L-オルニチンによる成長ホルモン分泌促進メカニズムの解析
2020.12 - 2023.5
Joint research
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Authorship：Principal investigator Grant type：Other funds from industry-academia collaboration
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成長初期の光環境応答性を利用した産肉性制御システムの生物学的基盤
2020.4 - 2024.3
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Authorship：Principal investigator
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大豆イソフラボンによる概日時計の保護に関する研究
2020.4 - 2023.3
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Authorship：Principal investigator
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不規則な明暗周期による概日時計の乱れとその改善効果を評価するための細胞実験系の確立
2020.4 - 2021.3
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Authorship：Principal investigator
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Mechanisms underlying beef production system with enduring effects of early-life photoperiod
Grant number：20K06366 2020 - 2022
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Yasuo Shinobu
More details
Authorship：Principal investigator Grant type：Scientific research funding
Appropriate management of lighting condition is important in livestock. The present study analyzed effect of postnatal photoperiod on growth and muscle development as well as molecular/epigenetic mechanisms using mice and Japanese Black cows. Gradually increasing photoperiod promoted body weight gain in mice. RNA-seq analysis revealed that expression of hypothalamic genes involved in growth and neuron development were widely altered by postnatal photoperiod. Cows exposed to long-day condition during postnatal period exhibited higher weight of total carcass at slaughter, compared to those exposed to short-day condition. Several modifications of histone proteins were significantly altered by postnatal photoperiod over several years.
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不規則な明暗周期による概日時計の乱れとその改善効果を評価するための細胞実験系の確立
2020
公益財団法人アサヒグループ学術振興財団 研究助成
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Authorship：Principal investigator Grant type：Contract research
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大豆イソフラボンによる概日時計の保護に関する研究
2020
公益財団法人不二たん白質研究振興財団 研究助成
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Authorship：Principal investigator Grant type：Contract research
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体内時計の撹乱評価モデルの確立と撹乱予防栄養素の探索
2019.4 - 2020.3
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Authorship：Principal investigator
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体内時計の撹乱評価モデルの確立と撹乱予防栄養素の探索
2019
サッポロ生物科学振興財団 研究助成
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Authorship：Principal investigator Grant type：Contract research
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食事リズムによる脳機能の調整
2018.4 - 2020.3
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Authorship：Principal investigator
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食事リズムによる脳機能の調整
2018 - 2019
ロッテ財団 第5回「奨励研究助成」
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Authorship：Principal investigator Grant type：Contract research
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L-オルニチンによるホルモン分泌調節機序
2017.5 - 2020.3
Joint research
More details
Authorship：Principal investigator Grant type：Other funds from industry-academia collaboration
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異なるライフステージに及ぶ影響を視野に入れた食事リズムと脳機能との関連解析
2017.4 - 2019.3
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Authorship：Principal investigator
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異なるライフステージに及ぶ影響を視野に入れた食事リズムと脳機能との関連解析
Grant number：17K19914 2017 - 2018
Grants-in-Aid for Scientific Research Grant-in-Aid for challenging Exploratory Research
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Authorship：Principal investigator Grant type：Scientific research funding
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研究補助者雇用支援（教授・准教授育児期支援）
2017 - 2018
研究補助者雇用支援（教授・准教授育児期支援）
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Authorship：Principal investigator Grant type：On-campus funds, funds, etc.
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L-セリンの脳内作用機序に関する研究
2016.7 - 2017.8
Joint research
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Authorship：Principal investigator Grant type：Other funds from industry-academia collaboration
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哺乳期の長日処理による黒毛和種の代謝調節
2016
伊藤記念財団平成28年度研究助成
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Authorship：Principal investigator Grant type：Contract research
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若齢期の日長が成熟後の神経形態および記憶・学習能力に及ぼす影響
2016
農学研究院若手教員支援事業（チャレンジ研究支援（Ⅱ型））
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Authorship：Principal investigator Grant type：On-campus funds, funds, etc.
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生体の光応答性と代謝プログラミングを活用した新規家畜生産システムの開発
2015.7 - 2018.3
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Authorship：Principal investigator
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L-セリンによる生物時計制御
2015.5 - 2016.4
Joint research
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Authorship：Principal investigator Grant type：Other funds from industry-academia collaboration
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アミノ酸栄養と運動による総合的な体内時計調整への挑戦
2015.4 - 2017.3
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Authorship：Principal investigator
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光条件の操作による家禽の肉質制御
2015.4 - 2016.3
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Authorship：Principal investigator
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生体の光応答性と代謝プログラミングを活用した新規家畜生産システムの開発
2015 - 2017
農林水産業・食品産業科学技術研究推進事業 シーズ創出ステージ
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Authorship：Principal investigator Grant type：Contract research
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アミノ酸栄養と運動による総合的な体内時計調整への挑戦
Grant number：15K12341 2015 - 2016
Grants-in-Aid for Scientific Research Grant-in-Aid for challenging Exploratory Research
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Authorship：Principal investigator Grant type：Scientific research funding
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光条件の操作による家禽の肉質制御
2015
財団法人旗影会 研究助成
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Authorship：Principal investigator Grant type：Contract research
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情動の季節リズムを制御する脳−末梢臓器連関
2014.3 - 2018.3
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Authorship：Principal investigator
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末梢臓器の代謝に着目した情動の季節リズム制御機構
2014
九州大学教育研究プログラム・研究拠点形成プロジェクト FSタイプ
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Authorship：Principal investigator Grant type：On-campus funds, funds, etc.
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L-セリンによる生物時計制御
2013.6 - 2014.5
Joint research
More details
Authorship：Principal investigator Grant type：Other funds from industry-academia collaboration
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様々なタンパク質源摂取による冬季うつ病の予防改善効果の解析
2013 - 2014
浦上食品・食文化振興財団研究助成
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Authorship：Principal investigator Grant type：Contract research
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概日リズムの攪乱を改善する栄養素の解析：慢性的時差ぼけモデルを用いたアプローチ
2013 - 2014
三島海雲記念財団学術研究奨励金
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Authorship：Principal investigator Grant type：Contract research
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概日リズム調節機能をもつ栄養素の解析
2012.4 - 2015.3
More details
Authorship：Principal investigator
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栄養の概日リズム調節特性を利用した光栄養療法の開発
2012 - 2013
Grants-in-Aid for Scientific Research Grant-in-Aid for challenging Exploratory Research
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Authorship：Coinvestigator(s) Grant type：Scientific research funding
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情動の季節リズムを制御する光時空間的生体機構
Grant number：24780286 2012 - 2013
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
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Authorship：Principal investigator Grant type：Scientific research funding
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医農理工文連携による 「におい」の最先端総合研究
2012 - 2013
九州大学教育研究プログラム・研究拠点形成プロジェクト E-3タイプ
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Authorship：Coinvestigator(s) Grant type：On-campus funds, funds, etc.
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概日時計を調節する機能性食品因子の解析
2012
財団法人食生活研究会 研究助成
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Authorship：Principal investigator Grant type：Contract research
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情動の季節周期を制御する分子神経基盤
2011.4 - 2015.3
More details
Authorship：Principal investigator
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新規アミノ酸栄養学の構築とその応用に関する研究
2011 - 2013
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)
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Authorship：Coinvestigator(s) Grant type：Scientific research funding
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概日リズム調節機能をもつ栄養素の解析
2011 - 2012
上原記念生命科学財団 平成23年度研究奨励金
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Authorship：Principal investigator Grant type：Contract research
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情動の季節周期を制御する分子神経基盤
2011 - 2012
住友財団 基礎科学研究助成
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Authorship：Principal investigator Grant type：Contract research
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自然由来揮発成分の生物時計を切り口とした機能解析
2011 - 2012
農学研究院若手教員支援事業（プロジェクト支援）
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Authorship：Coinvestigator(s) Grant type：On-campus funds, funds, etc.
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情動・代謝を制御する光周性機構の解明と栄養学的考察
2010 - 2011
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (Start-up)
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Authorship：Principal investigator Grant type：Scientific research funding
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情動機能の季節変化を制御するメカニズムの解明
2010
（財）武田科学 平成22年度ライフサイエンス研究奨励
More details
Authorship：Principal investigator Grant type：Contract research
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アミノ酸が家禽の概日時計および光周性機構に及ぼす影響
2010
(財)九州大学後援会 平成22年度研究助成
More details
Authorship：Principal investigator Grant type：Contract research
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アミノ酸栄養が家禽動物の概日時計および光周性機構に及ぼす影響の解明
2010
(財)旗影会 平成22年度研究助成
More details
Authorship：Principal investigator Grant type：Contract research
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エンドカンナビノイドの新規作用機序とその生物学的意義の解明
2010
九州大学教育研究プログラム・研究拠点形成プロジェクト 「萌芽的若手研究」
More details
Authorship：Principal investigator Grant type：On-campus funds, funds, etc.
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哺乳類の視床下部内側基底部における光周性制御機構
2006 - 2007
Japan Society for the Promotion of Science Postdoctoral Fellowships for Research Abroad
More details
Authorship：Principal investigator Grant type：Joint research
Educational Activities
Educational Activities
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I am in charge of cell biology, animal physiology, or animal husbandry management for undergraduates, and regulatory biology and related seminars for graduates.
Class subject
Class subject
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動物生理学Ⅱ
2025.12 - 2026.2 Winter quarter
-
動物生産科学概論
2025.10 - 2026.3 Second semester
-
動物飼養生体制御学実験
2025.10 - 2026.3 Second semester
-
動物・海洋生物科学演習第一
2025.10 - 2026.3 Second semester
-
動物・海洋生物科学演習第二
2025.10 - 2026.3 Second semester
-
生体制御システム学特論
2025.10 - 2026.3 Fall quarter
-
農学入門II
2025.4 - 2026.3 Full year
-
飼料学実験
2025.4 - 2025.9 First semester
-
Environmental and Ecological Science for Animal Production Ⅰ
2025.4 - 2025.9 Spring quarter
-
動物飼養生体制御学Ⅰ
2025.4 - 2025.6 Spring quarter
-
動物生理学Ⅱ
2024.12 - 2025.2 Winter quarter
-
動物生産科学概論
2024.10 - 2025.3 Second semester
-
動物飼養生体制御学実験
2024.10 - 2025.3 Second semester
-
細胞生物学
2024.10 - 2025.3 Second semester
-
動物・海洋生物科学演習第一
2024.10 - 2025.3 Second semester
-
動物・海洋生物科学演習第二
2024.10 - 2025.3 Second semester
-
生体制御システム学特論
2024.10 - 2024.12 Fall quarter
-
農学入門II
2024.4 - 2025.3 Full year
-
飼料学実験
2024.4 - 2024.9 First semester
-
Environmental and Ecological Science for Animal Production Ⅰ
2024.4 - 2024.6 Spring quarter
-
動物飼養生体制御学Ⅰ
2024.4 - 2024.6 Spring quarter
-
動物生理学Ⅱ
2023.12 - 2024.2 Winter quarter
-
動物生産科学概論
2023.10 - 2024.3 Second semester
-
動物飼養生体制御学実験
2023.10 - 2024.3 Second semester
-
細胞生物学
2023.10 - 2024.3 Second semester
-
動物・海洋生物科学演習第一
2023.10 - 2024.3 Second semester
-
動物・海洋生物科学演習第二
2023.10 - 2024.3 Second semester
-
生体制御システム学特論
2023.10 - 2023.12 Fall quarter
-
農学入門II
2023.4 - 2024.3 Full year
-
飼料学実験
2023.4 - 2023.9 First semester
-
Environmental and Ecological Science for Animal Production Ⅰ
2023.4 - 2023.6 Spring quarter
-
動物飼養生体制御学Ⅰ
2023.4 - 2023.6 Spring quarter
-
動物生理学Ⅱ
2022.12 - 2023.2 Winter quarter
-
動物生産科学概論
2022.10 - 2023.3 Second semester
-
細胞生物学
2022.10 - 2023.3 Second semester
-
動物・海洋生物科学演習第二
2022.10 - 2023.3 Second semester
-
動物飼養生体制御学実験
2022.10 - 2023.3 Second semester
-
動物・海洋生物科学演習第一
2022.10 - 2023.3 Second semester
-
動物生理学Ⅰ
2022.10 - 2022.12 Fall quarter
-
生体制御システム学特論
2022.10 - 2022.12 Fall quarter
-
動物飼養生体制御学II
2022.6 - 2022.8 Summer quarter
-
農学入門II
2022.4 - 2023.3 Full year
-
Environmental and Ecological Science for Animal Production
2022.4 - 2022.9 First semester
-
Animal and Marine Life Science
2022.4 - 2022.9 First semester
-
飼料学実験
2022.4 - 2022.9 First semester
-
動物飼養生体制御学I
2022.4 - 2022.6 Spring quarter
-
動物生理学Ⅱ
2021.12 - 2022.2 Winter quarter
-
動物生産科学概論
2021.10 - 2022.3 Second semester
-
家畜飼養管理学実験
2021.10 - 2022.3 Second semester
-
動物・海洋生物科学演習第一
2021.10 - 2022.3 Second semester
-
動物・海洋生物科学演習第二
2021.10 - 2022.3 Second semester
-
細胞生物学
2021.10 - 2022.3 Second semester
-
動物生理学Ⅰ
2021.10 - 2021.12 Fall quarter
-
生体制御システム学特論
2021.10 - 2021.12 Fall quarter
-
農学入門II
2021.4 - 2022.3 Full year
-
Environmental and Ecological Science for Animal Production
2021.4 - 2021.9 First semester
-
飼料学実験
2021.4 - 2021.9 First semester
-
家畜飼養管理学
2021.4 - 2021.9 First semester
-
Animal and Marine Life Science
2021.4 - 2021.9 First semester
-
動物・海洋生物科学プロジェクト演習
2020.10 - 2021.3 Second semester
-
動物生産科学概論
2020.10 - 2021.3 Second semester
-
動物生理学
2020.10 - 2021.3 Second semester
-
家畜飼養管理学実験
2020.10 - 2021.3 Second semester
-
細胞生物学
2020.10 - 2021.3 Second semester
-
動物・海洋生物科学演習第二
2020.10 - 2021.3 Second semester
-
動物・海洋生物科学演習第一
2020.10 - 2021.3 Second semester
-
生体制御システム学特論
2020.10 - 2020.12 Fall quarter
-
農学入門II
2020.4 - 2021.3 Full year
-
Animal and Marine Life Science
2020.4 - 2020.9 First semester
-
家畜飼養管理学
2020.4 - 2020.9 First semester
-
飼料学実験
2020.4 - 2020.9 First semester
-
Environmental and Ecological Science for Animal Production
2020.4 - 2020.9 First semester
-
生体制御システム学特論
2019.10 - 2020.3 Second semester
-
動物生産科学概論
2019.10 - 2020.3 Second semester
-
動物生理学
2019.10 - 2020.3 Second semester
-
家畜飼養管理学実験
2019.10 - 2020.3 Second semester
-
細胞生物学
2019.10 - 2020.3 Second semester
-
動物・海洋生物科学演習第二
2019.10 - 2020.3 Second semester
-
動物・海洋生物科学演習第一
2019.10 - 2020.3 Second semester
-
動物・海洋生物科学プロジェクト演習
2019.10 - 2020.3 Second semester
-
農学入門II
2019.4 - 2020.3 Full year
-
Animal and Marine Life Science
2019.4 - 2019.9 First semester
-
家畜飼養管理学
2019.4 - 2019.9 First semester
-
Environmental and Ecological Science for Animal Production
2019.4 - 2019.9 First semester
-
生体制御システム学特論
2018.10 - 2019.3 Second semester
-
動物生産科学概論
2018.10 - 2019.3 Second semester
-
動物生理学
2018.10 - 2019.3 Second semester
-
家畜飼養管理学実験
2018.10 - 2019.3 Second semester
-
細胞生物学
2018.10 - 2019.3 Second semester
-
動物・海洋生物科学演習第二
2018.10 - 2019.3 Second semester
-
動物・海洋生物科学演習第一
2018.10 - 2019.3 Second semester
-
動物・海洋生物科学プロジェクト演習
2018.10 - 2019.3 Second semester
-
農学入門II
2018.4 - 2019.3 Full year
-
Animal and Marine Life Science
2018.4 - 2018.9 First semester
-
家畜飼養管理学
2018.4 - 2018.9 First semester
-
Environmental and Ecological Science for Animal Production
2018.4 - 2018.9 First semester
-
飼養管理学演習
2017.10 - 2018.3 Second semester
-
動物生理学
2017.10 - 2018.3 Second semester
-
家畜飼養管理学実験
2017.10 - 2018.3 Second semester
-
細胞生物学
2017.10 - 2018.3 Second semester
-
生体制御システム学特論
2017.10 - 2018.3 Second semester
-
生体制御システム学演習
2017.10 - 2018.3 Second semester
-
動物・海洋生物資源学輪講
2017.4 - 2018.3 Full year
-
農学入門II
2017.4 - 2018.3 Full year
-
動物生体機能学特論
2017.4 - 2017.9 First semester
-
家畜飼養管理学
2017.4 - 2017.9 First semester
-
Environmental and Ecological Science for Animal Production
2017.4 - 2017.9 First semester
-
Animal and Marine Life Science
2017.4 - 2017.9 First semester
-
飼養管理学演習
2016.10 - 2017.3 Second semester
-
動物生理学
2016.10 - 2017.3 Second semester
-
家畜飼養管理学実験
2016.10 - 2017.3 Second semester
-
細胞生物学
2016.10 - 2017.3 Second semester
-
生体制御システム学特論
2016.10 - 2017.3 Second semester
-
生体制御システム学演習
2016.10 - 2017.3 Second semester
-
動物・海洋生物資源学輪講
2016.4 - 2017.3 Full year
-
農学入門II
2016.4 - 2017.3 Full year
-
動物生体機能学特論
2016.4 - 2016.9 First semester
-
家畜飼養管理学
2016.4 - 2016.9 First semester
-
Environmental and Ecological Science for Animal Production
2016.4 - 2016.9 First semester
-
Animal and Marine Life Science
2016.4 - 2016.9 First semester
-
飼養管理学演習
2015.10 - 2016.3 Second semester
-
動物生理学
2015.10 - 2016.3 Second semester
-
家畜飼養管理学実験
2015.10 - 2016.3 Second semester
-
細胞生物学
2015.10 - 2016.3 Second semester
-
生体制御システム学特論
2015.10 - 2016.3 Second semester
-
生体制御システム学演習
2015.10 - 2016.3 Second semester
-
動物・海洋生物資源学輪講
2015.4 - 2016.3 Full year
-
農学入門II
2015.4 - 2016.3 Full year
-
動物生体機能学特論
2015.4 - 2015.9 First semester
-
家畜飼養管理学
2015.4 - 2015.9 First semester
-
Environmental and Ecological Science for Animal Production
2015.4 - 2015.9 First semester
-
Animal and Marine Life Science
2015.4 - 2015.9 First semester
-
飼養管理学演習
2014.10 - 2015.3 Second semester
-
科学英語
2014.10 - 2015.3 Second semester
-
家畜飼養管理学実験
2014.10 - 2015.3 Second semester
-
細胞生物学
2014.10 - 2015.3 Second semester
-
生体制御システム学特論
2014.10 - 2015.3 Second semester
-
生体制御システム学演習
2014.10 - 2015.3 Second semester
-
動物・海洋生物資源学輪講
2014.4 - 2015.3 Full year
-
農学入門II
2014.4 - 2015.3 Full year
-
動物生体機能学特論
2014.4 - 2014.9 First semester
-
動物遺伝育種学
2014.4 - 2014.9 First semester
-
Environmental and Ecological Science for Animal Production
2014.4 - 2014.9 First semester
-
Animal and Marine Life Science
2014.4 - 2014.9 First semester
-
飼養管理学演習
2013.10 - 2014.3 Second semester
-
家畜飼養管理学実験
2013.10 - 2014.3 Second semester
-
細胞生物学
2013.10 - 2014.3 Second semester
-
生体制御システム学特論
2013.10 - 2014.3 Second semester
-
動物・海洋生物資源学輪講
2013.4 - 2014.3 Full year
-
動物生産科学概要
2013.4 - 2014.3 Full year
-
動物生体機能学特論
2013.4 - 2013.9 First semester
-
動物遺伝育種学
2013.4 - 2013.9 First semester
-
Environmental and Ecological Science for Animal Production
2013.4 - 2013.9 First semester
-
Animal and Marine Life Science
2013.4 - 2013.9 First semester
-
飼養管理学演習
2012.10 - 2013.3 Second semester
-
家畜飼養管理学実験
2012.10 - 2013.3 Second semester
-
細胞生物学
2012.10 - 2013.3 Second semester
-
生体制御システム学特論
2012.10 - 2013.3 Second semester
-
動物・海洋生物資源学輪講
2012.4 - 2013.3 Full year
-
動物生産科学概要
2012.4 - 2013.3 Full year
-
Environmental and Ecological Science for Animal Production
2012.4 - 2012.9 First semester
-
動物遺伝育種学
2012.4 - 2012.9 First semester
-
動物生体機能学特論
2012.4 - 2012.9 First semester
-
飼養管理学演習
2011.10 - 2012.3 Second semester
-
家畜飼養管理学実験
2011.10 - 2012.3 Second semester
-
細胞生物学
2011.10 - 2012.3 Second semester
-
生体制御システム学特論
2011.10 - 2012.3 Second semester
-
生体制御システム学演習
2011.10 - 2012.3 Second semester
-
動物・海洋生物資源学輪講
2011.4 - 2012.3 Full year
-
動物生産科学概要
2011.4 - 2012.3 Full year
-
動物生体機能学特論
2011.4 - 2011.9 First semester
-
動物遺伝育種学
2011.4 - 2011.9 First semester
-
コアセミナー
2011.4 - 2011.9 First semester
-
飼養管理学演習
2010.10 - 2011.3 Second semester
-
細胞生物学
2010.10 - 2011.3 Second semester
-
生体制御システム学特論
2010.10 - 2011.3 Second semester
-
動物・海洋生物資源学輪講
2010.4 - 2011.3 Full year
-
動物生産科学概要
2010.4 - 2011.3 Full year
-
動物生体機能学特論
2010.4 - 2010.9 First semester
-
動物遺伝育種学
2010.4 - 2010.9 First semester
-
動物生産科学概要
2009.10 - 2010.3 Second semester
FD Participation
FD Participation
-
2025.1 Role：Participation Title：農学研究院FD：DX化によって広がる研究の可能性
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2024.12 Role：Participation Title：競争的資金獲得に向けた農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2023.11 Role：Participation Title：農学研究院FD：遺伝子組換え実験の安全管理について
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2023.9 Role：Participation Title：M2Bシステムの使い方 ～Moodleのバージョンアップによる変更点を中心に紹介します～
Organizer：University-wide
-
2022.3 Role：Participation Title：全学FD:メンタルヘルス講演会
Organizer：University-wide
-
2021.9 Role：Participation Title：JST 次世代研究者挑戦的研究プログラム 説明会
Organizer：University-wide
-
2021.7 Role：Participation Title：農学研究院FD「科研費を獲りにいこう！ 科研費獲得の技術と工夫」
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2020.12 Role：Participation Title：大学の研究評価の現状と農学研究院の「部局独自の評価基準」案における業績分析
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2020.12 Role：Participation Title：農学研究院ＦＤ「大学の研究評価の現状と農学研究院の「部局独自の評価基準」案における業績分析」
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2020.9 Role：Participation Title：科研費を獲りにいこう！ 勝ち抜く気合と技術
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2020.9 Role：Participation Title：農学研究院ＦＤ「科研費を獲りにいこう！」
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2020.6 Role：Participation Title：農学研究院ＦＤ「九州大学はどのような教育を目指していくのか」
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2019.12 Role：Participation Title：令和元年度 農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2018.3 Role：Participation Title：平成29年度 第5回農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2017.9 Role：Participation Title：平成29年度 第3回農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2016.11 Role：Participation Title：平成２８年度第2回農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2016.7 Role：Participation Title：平成２８年度第１回農学研究院ＦＤ
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2016.2 Role：Participation Title：平成27年度農学研究院第3回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2015.11 Role：Participation Title：平成27年度農学研究院第2回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2015.9 Role：Participation Title：平成27年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2014.9 Role：Participation Title：新GPA制度に係るFD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2014.7 Role：Participation Title：平成26年度農学研究院第2回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2014.5 Role：Participation Title：平成26年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2013.11 Role：Participation Title：平成25年度農学研究院第2回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2013.7 Role：Participation Title：平成25年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2012.11 Role：Participation Title：平成24年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2011.9 Role：Participation Title：平成23年度農学研究院第5回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2011.8 Role：Participation Title：平成23年度農学研究院第4回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2011.7 Role：Participation Title：平成23年度農学研究院第3回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2011.5 Role：Participation Title：平成23年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2011.3 Role：Participation Title：平成22年度農学研究院第5回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2010.9 Role：Participation Title：平成22年度農学研究院第4回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2010.7 Role：Participation Title：平成22年度農学研究院第3回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2010.6 Role：Participation Title：平成22年度農学研究院第2回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2010.4 Role：Participation Title：平成22年度農学研究院第1回FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
-
2010.1 Role：Participation Title：農学研究院FD
Organizer：[Undergraduate school/graduate school/graduate faculty]
Visiting, concurrent, or part-time lecturers at other universities, institutions, etc.
Visiting, concurrent, or part-time lecturers at other universities, institutions, etc.
-
2023 東北大学 Classification:Intensive course Domestic/International Classification:Japan
-
2023 早稲田大学 Classification:Part-time lecturer Domestic/International Classification:Japan
-
2022 早稲田大学 Classification:Part-time lecturer Domestic/International Classification:Japan
Social Activities
Social Activities
-
体内時計のしくみを活用した現代社会の健康増進 ～生活リズム・ライフステージ・性差を考慮したヘルスケアへ向けて～
Role(s)：Lecturer
九州大学 九大フェスタ in 東京 研究成果発表会 2024.8
-
体内時計にあわせた食生活から考える未来の健康科学
佐賀清和高等学校 2022.10
More details
Audience：Infants, Schoolchildren, Junior students, High school students
Type：Seminar, workshop
-
日本食品保険指導士会九州支部 指導士スキルアップ研修における講師
日本食品保険指導士会九州支部 2022.2
More details
Audience：General, Scientific, Company, Civic organization, Governmental agency
Type：Seminar, workshop
-
高校生の進路選択のための夢ナビ講義動画および夢ナビライブ出演
フロムページ 2021.10
More details
Audience：Infants, Schoolchildren, Junior students, High school students
Type：Seminar, workshop
-
長崎県の栄養士会により開催された生涯教育研修会にて、時間栄養学に関するセミナーを行なった。
長崎県栄養士会 2019.9
More details
Audience：General, Scientific, Company, Civic organization, Governmental agency
Type：Seminar, workshop
-
中学生のための九大模擬授業
糸島市 2018.10
More details
Audience：Infants, Schoolchildren, Junior students, High school students
Type：Seminar, workshop
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福岡市科学館にて、「体内時計ってなんだろう？」と題した一般講演会を開催した。
福岡市科学館/九州山口沖縄リズム研究会 福岡市科学館 2018.4
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Audience：General, Scientific, Company, Civic organization, Governmental agency
Type：Lecture
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平成28年度女子中高生の進路選択応援事業
2016.8
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Audience：Infants, Schoolchildren, Junior students, High school students
Type：Seminar, workshop
Media Coverage
Media Coverage
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Females are more prone to circadian clock disruption than males ̶ Expectations for shift worker health management incorporating gender differences Internet
Science Japan JST News 2025.4
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JST News 2025年3月号の英語版
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雌性生物雄性更易紊乱，有望推僢基于性Ģ差的班健康管理餡化 Internet
中国向けポータルサイト「客観日本」 2025.3
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JST News 2025年3月号の中国語版
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Chronic jet lag disrupts metabolism differently in male and female mice Internet
九州大学 海外向けホームページ 2025.3
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令和6年12月9日のプレスリリース「メスの体内時計は時差ぼけに弱い ～マウス実験で発見、性差を考慮したシフトワーカーの健康管理に期待～」と関連
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Sex differences of chronic jet lag in mice Internet
EulekAlert 2025.3
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令和7年3月20日の海外プレスリリース「Chronic jet lag disrupts metabolism differently in male and female mice」についての報道
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Jet Lag Affects Male and Female Mice Differently, Study Finds Internet
Psychreg 2025.3
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令和7年3月20日の海外プレスリリース「Chronic jet lag disrupts metabolism differently in male and female mice」についての報道
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Chronic jet lag disrupts metabolism differently in male and female mice, study finds Internet
Medical Press 2025.3
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令和7年3月20日の海外プレスリリース「Chronic jet lag disrupts metabolism differently in male and female mice」についての報道
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Chronic Jet Lag Impairs Circadian Rhythms Differently in Males and Females, Study Finds Internet
Sustain Health 2025.3
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令和7年3月20日の海外プレスリリース「Chronic jet lag disrupts metabolism differently in male and female mice」についての報道
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メスの体内時計はオスよりも乱れやすい Newspaper, magazine
JST News 2025年3月号 2025.3
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令和6年12月9日のプレスリリース「メスの体内時計は時差ぼけに弱い ～マウス実験で発見、性差を考慮したシフトワーカーの健康管理に期待～」と関連
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体内時計 乱れに性差 シフト勤務・時差ぼけ 健康管理へ応用期待 Newspaper, magazine
日刊工業新聞 2024.12
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令和6年12月9日のプレスリリース「メスの体内時計は時差ぼけに弱い ～マウス実験で発見、性差を考慮したシフトワーカーの健康管理に期待～」についての報道
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プレスリリース「メスの体内時計は時差ぼけに弱い ～マウス実験で発見、性差を考慮したシフトワーカーの健康管理に期待～」 Internet
九州大学・JSTホームページ 2024.12
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ロッテ財団の研究助成で実施した体内時計と脳機能に関する研究についての紹介記事 Newspaper, magazine
日本経済新聞 2022.3
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ロッテ財団の研究助成で実施した体内時計と脳機能に関する研究についての紹介記事
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平成29年10月26日のプレスリリース「アミノ酸の一種L-セリン摂取で体内時計の修正が容易に－体内時計の乱れや時差ぼけの改善に期待－」についての報道 Newspaper, magazine
西日本新聞 2017.11
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平成29年10月26日のプレスリリース「アミノ酸の一種L-セリン摂取で体内時計の修正が容易に－体内時計の乱れや時差ぼけの改善に期待－」についての報道
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情動の光周性に関する学会発表紹介記事 Newspaper, magazine
Medical Tribune 2012.3
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情動の光周性に関する学会発表紹介記事
Acceptance of Foreign Researchers, etc.
Acceptance of Foreign Researchers, etc.
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University of Pecs
Acceptance period： 2012.4 - 2012.10 （Period）：1 month or more
Nationality：Hungary
Business entity：Private/Foundation
Travel Abroad
Travel Abroad
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2023.12
Staying countory name 1：China Staying institution name 1：Northwest A&F University
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2014.2
Staying countory name 1：Germany Staying institution name 1：Leibniz Institute for Farm Animal Biology
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2013.8 - 2013.9
Staying countory name 1：Germany Staying institution name 1：Technical University Munich
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2013.8
Staying countory name 1：Germany Staying institution name 1：Ludwig Maximilian University Munich
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2012.3
Staying countory name 1：Germany Staying institution name 1：Goethe University Frankfurt am Main
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2011.6 - 2011.7
Staying countory name 1：United States Staying institution name 1：Snowmass Village, CO
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2010.8 - 2010.9
Staying countory name 1：Hungary Staying institution name 1：University of Pecs Medical School
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2007.11 - 2009.11
Staying countory name 1：Germany Staying institution name 1：Institute of Anatomy II, Goethe University Frankfurt
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2005.11 - 2007.10
Staying countory name 1：Germany Staying institution name 1：Institute of Anatomy II, Goethe University Frankfurt