Updated on 2024/06/10

Information

 

写真a

 
YAMADA TAISHO
 
Organization
Medical Institute of Bioregulation Research Center for Systems Immunology Assistant Professor
Title
Assistant Professor
Profile
In order to identify the molecular mechanism of severe viral disease, I am promoting research with a particular focus on the host's innate immune response.

Degree

  • Ph.D.

Research Interests・Research Keywords

  • Research theme:Elucidation of the molecular mechanisms involved in severe viral disease

    Keyword:Innate immunity, viral infection, interferon, signal transduction

    Research period: 2023.4 - 2024.5

Awards

  • 第17回日本インターフェロン・サイトカイン学会奨励賞

    2021.5  

  • 北海道医学会 研究奨励賞

    2017.3  

  • 北海道大学医学部同窓会 フラテ研究奨励賞

    2017.2  

  • ICI-FIMSA Travel Awards (Austraria)

    2016.8  

Papers

  • Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells Reviewed

    Nabeel Kajihara, Yoshino Tanaka, Riko Takeuchi, Takuto Kobayashi, Masafumi Tanji, Tsukasa Ataka, Shiho Nakano, Taisho Yamada, Akinori Takaoka, Yoshinori Hasegawa, Ken-Ichiro Seino, Haruka Wada

    OncoImmunology   12 ( 1 )   2213132   2023.5

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/2162402x.2023.2213132

  • Innate immune recognition against SARS-CoV-2

    Taisho Yamada, Akinori Takaoka

    Inflammation and Regeneration   43 ( 1 )   2023.1

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    Language:Others   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s41232-023-00259-5

  • Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection Reviewed International journal

    Sunanda Baidya, Yoko Nishimoto, Seiichi Sato, Yasuhiro Shimada, Nozomi Sakurai, Hirotaka Nonaka, Koki Noguchi, Mizuki Kido, Satoshi Tadano, Kozo Ishikawa, Kai Li, Aoi Okubo, Taisho Yamada, Yasuko Orba, Michihito Sasaki, Hirofumi Sawa, Hiroko Miyamoto, Ayato Takada, Takashi Nakamura, Akinori Takaoka

    Viruses   13 ( 9 )   1674 - 1674   2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/v13091674

  • RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells Reviewed International journal

    Taisho Yamada, Seiichi Sato, Yuki Sotoyama, Yasuko Orba, Hirofumi Sawa, Hajime Yamauchi, Michihito Sasaki, Akinori Takaoka

    Nature Immunology   22 ( 7 )   820 - 828   2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41590-021-00942-0

  • Regulation of signaling mediated by nucleic acid sensors for innate interferon-mediated responses during viral infection. Reviewed

    Akinori Takaoka, Taisho Yamada

    International Immunology   15   dxz034   2019.4

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    Language:Others  

    Regulation of signaling mediated by nucleic acid sensors for innate interferon-mediated responses during viral infection.

    DOI: 10.1093/intimm/dxz034

  • Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense Reviewed

    Taisho Yamada, Hiromasa Horimoto, Takeshi Kameyama, Sumio Hayakawa, Hiroaki Yamato, Masayoshi Dazai, Ayato Takada, Hiroshi Kida, Debbie Bott, Angela C. Zhou, David Hutin, Tania H. Watts, Masahiro Asaka, Jason Matthews, Akinori Takaoka

    Nature Immunology   17 ( 6 )   687 - +   2016.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/ni.3422

  • ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses Reviewed

    Sumio Hayakawa, Souichi Shiratori, Hiroaki Yamato, Takeshi Kameyama, Chihiro Kitatsuji, Fumi Kashigi, Showhey Goto, Shoichiro Kameoka, Daisuke Fujikura, Taisho Yamada, Tatsuaki Mizutani, Mika Kazumata, Maiko Sato, Junji Tanaka, Masahiro Asaka, Yusuke Ohba, Tadaaki Miyazaki, Masahiro Imamura, Akinori Takaoka

    Nature Immunology   12 ( 1 )   37 - U56   2011.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/ni.1963

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MISC

  • [NF-kappaB signaling pathway and inflammation].

    Yamada T, Takaoka A

    Nihon rinsho. Japanese journal of clinical medicine   2012.11

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    Language:Others  

    [NF-kappaB signaling pathway and inflammation].

  • 抗ウイルス応答において活性化されるRIG-Iの強力な調節因子ZAPSの同定

    白鳥 聡一, 早川 清雄, 大和 弘明, 亀山 武志, 北辻 千展, 樫木 芙美, 後藤 翔平, 亀岡 章一郎, 藤倉 大輔, 山田 大翔, 水谷 龍明, 数馬田 美香, 佐藤 麻衣子, 田中 淳司, 浅香 正博, 大場 雄介, 宮崎 忠昭, 今村 雅寛, 高岡 晃教

    北海道醫學雜誌 = Acta medica Hokkaidonensia   2012.8

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    Language:Japanese  

Research Projects

  • SARS-CoV-2に対する自然免疫機構と重症化因子の影響に関する分子機構の解明

    Grant number:21K07049  2021 - 2023

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • ヒトサイトメガロウイルス感染に対する新規自然免疫シグナル調節機構の解析

    Grant number:19K16664  2019 - 2020

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • ウイルスに対する免疫応答を規定する非感染状態の免疫システムに関する研究

    Grant number:18K07162  2018 - 2020

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • ヒトサイトメガロウイルス感染により活性化される新規自然免疫応答活性化機構の解析

    Grant number:17K15698  2017 - 2018

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

  • ダイオキシン類曝露による自然免疫応答抑制機構の解明

    Grant number:16H06599  2016 - 2017

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Grant type:Scientific research funding

Class subject

  • 生体応答制御学

    2023.10 - 2024.3   Second semester