Tumor-dilated polymersome nanofactories for enhanced enzyme prodrug chemo-immunotherapy

Abd Al-Wali Mohammed M. Japir, Wendong Ke, Junjie Li, Jean Felix Mukerabigwi, Alhadi Ibrahim, Yuheng Wang, Xiang Li, Qinghao Zhou, Fathelrahman Mohammed, Zhishen Ge

Journal of Controlled Release   339   418 - 429   2021.11

Hypoxia-responsive block copolymer polyprodrugs for complementary photodynamic-chemotherapy

Qinghao Zhou, Fathelrahman Mohammed, Yuheng Wang, Jingbo Wang, Nannan Lu, Junjie Li, Zhishen Ge

Journal of Controlled Release   339   130 - 142   2021.11

Enzymatically Transformable Polymersome‐Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer

Junjie Li, Zhishen Ge, Kazuko Toh, Xueying Liu, Anjaneyulu Dirisala, Wendong Ke, Panyue Wen, Hang Zhou, Zheng Wang, Shiyan Xiao, Joachim F. R. Van Guyse, Theofilus A. Tockary, Jinbing Xie, Daniel Gonzalez‐Carter, Hiroaki Kinoh, Satoshi Uchida, Yasutaka Anraku, Kazunori Kataoka

33 ( 49 )   2105254 - 2105254   2021.10

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

Junjie Li, Kazunori Kataoka

Journal of the American Chemical Society   143 ( 2 )   538 - 559   2021.1

Self‐Boosting Catalytic Nanoreactors Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis Reviewed

59 ( 32 )   13526 - 13530   2020.8

Self‐Boosting Catalytic Nanoreactors Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis Reviewed

132 ( 32 )   13628 - 13632   2020.8

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines Reviewed International journal

Anjaneyulu Dirisala, Satoshi Uchida, Kazuko Toh, Junjie Li, Shigehito Osawa, Theofilus A. Tockary, Xueying Liu, Saed Abbasi, Kotaro Hayashi, Yuki Mochida, Shigeto Fukushima, Hiroaki Kinoh, Kensuke Osada, Kazunori Kataoka

Science Advances   6 ( 26 )   eabb8133 - eabb8133   2020.6

Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain Reviewed

Jinbing Xie, Daniel Gonzalez-Carter, Theofilus A. Tockary, Noriko Nakamura, Yonger Xue, Makoto Nakakido, Hiroki Akiba, Anjaneyulu Dirisala, Xueying Liu, Kazuko Toh, Tao Yang, Zengtao Wang, Shigeto Fukushima, Junjie Li, Sabina Quader, Kouhei Tsumoto, Takanori Yokota, Yasutaka Anraku, Kazunori Kataoka

ACS Nano   14 ( 6 )   6729 - 6742   2020.5

Therapeutic Polymersome Nanoreactors with Tumor-Specific Activable Cascade Reactions for Cooperative Cancer Therapy Reviewed

13 ( 2 )   2357 - 2369   2019.1

Sustained and Bioresponsive Two‐Stage Delivery of Therapeutic miRNA via Polyplex Micelle‐Loaded Injectable Hydrogels for Inhibition of Intervertebral Disc Fibrosis Reviewed

リージェンジェ

7   2018.11

Precise tuning of disulfide crosslinking in mRNA polyplex micelles for optimizing extracellular and intracellular nuclease tolerability Reviewed

Journal of drug targeting   2018.11

Intracellular glutathione-depleting polymeric micelles for cisplatin prodrug delivery to overcome cisplatin resistance of cancers Reviewed

Journal of Controlled Release   273   30 - 39   2018.3

Therapeutic Vesicular Nanoreactors with Tumor-Specific Activation and Self-Destruction for Synergistic Tumor Ablation Reviewed

Junjie Li, Anjaneyulu Dirisala, Zhishen Ge, Yuheng Wang, Wei Yin, Wendong Ke, Kazuko Toh, Jinbing Xie, Yu Matsumoto, Yasutaka Anraku, Kensuke Osada, Kazunori Kataoka

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   56 ( 45 )   14025 - 14030   2017.11

Polymer Prodrug-Based Nanoreactors Activated by Tumor Acidity for Orchestrated Oxidation/Chemotherapy Reviewed

Nano letters   17   2017.10

Therapeutic Vesicular Nanoreactors with Tumor‐Specific Activation and Self‐Destruction for Synergistic Tumor Ablation Reviewed

リージェンジェ

129   14213 - 14218   2017.9

Light‐Triggered Clustered Vesicles with Self‐Supplied Oxygen and Tissue Penetrability for Photodynamic Therapy against Hypoxic Tumor Reviewed

リージェンジェ

27 ( 33 )   1702108   2017.9

Integrated Nanoparticles To Synergistically Elevate Tumor Oxidative Stress and Suppress Antioxidative Capability for Amplified Oxidation Therapy Reviewed

ACS applied materials & interfaces   9 ( 35 )   29538 - 29546   2017.8

Smart Asymmetric Vesicles with Triggered Availability of Inner Cell-Penetrating Shells for Specific Intracellular Drug Delivery Reviewed

Junjie Li, Shiyan Xiao, Yixuan Xu, Shuai Zuo, Zengshi Zha, Wendong Ke, Chuanxin He, Zhishen Ge

ACS APPLIED MATERIALS & INTERFACES   9 ( 21 )   17727 - 17735   2017.5

Facile Preparation and Radiotherapy Application of an Amphiphilic Block Copolymer Radiosensitizer Reviewed

Kaijie Zhao, Wendong Ke, Wei Yin, Junjie Li, Ming Qiang, Zhishen Ge

ACS MACRO LETTERS   6 ( 5 )   556 - 560   2017.5

Modular Design and Facile Synthesis of Enzyme-Responsive Peptide-Linked Block Copolymers for Efficient Delivery of Doxorubicin Reviewed

Biomacromolecules   17 ( 10 )   3268 - 3276   2016.9

Finely Tuned Thermo‐Responsive Block Copolymer Micelles for Photothermal Effect‐Triggered Efficient Cellular Internalization Reviewed

リージェンジェ

16 ( 9 )   1265 - 1272   2016.9

Dual Stimuli-Responsive Polymer Prodrugs Quantitatively Loaded by Nanoparticles for Enhanced Cellular Internalization and Triggered Drug Release Reviewed

Mingming Huang, Kaijie Zhao, Lei Wang, Shanqing Lin, Junjie Li, Jingbo Chen, Chengai Zhao, Zhishen Ge

ACS APPLIED MATERIALS & INTERFACES   8 ( 18 )   11226 - 11236   2016.5

Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy Reviewed

Junjie Li, Wendong Ke, Lei Wang, Mingming Huang, Wei Yin, Ping Zhang, Qixian Chen, Zhishen Ge

JOURNAL OF CONTROLLED RELEASE   225   64 - 74   2016.3

Endogenous Stimuli‐Sensitive Multistage Polymeric Micelleplex Anticancer Drug Delivery System for Efficient Tumor Penetration and Cellular Internalization Reviewed

リージェンジェ

4 ( 15 )   2206 - 2219   2015.10

A Near‐Infrared Photothermal Effect‐Responsive Drug Delivery System Based on Indocyanine Green and Doxorubicin‐Loaded Polymeric Micelles Mediated by Reversible Diels–Alder Reaction Reviewed

リージェンジェ

36 ( 20 )   1841 - 1849   2015.10

Endosomal-escape polymers based on multicomponent reaction-synthesized monomers integrating alkyl and imidazolyl moieties for efficient gene delivery Reviewed

ACS Macro Letters   4 ( 10 )   1123 - 1127   2015.9

Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery Reviewed

Junjie Li, Qixian Chen, Zengshi Zha, Hui Li, Kazuko Toh, Anjaneyulu Dirisala, Yu Matsumoto, Kensuke Osada, Kazunori Kataoka, Zhishen Ge

JOURNAL OF CONTROLLED RELEASE   209   77 - 87   2015.7

Gene therapy for nucleus pulposus regeneration by heme oxygenase-1 plasmid DNA carried by mixed polyplex micelles with thermo-responsive heterogeneous coronas Reviewed

Ganjun Feng, Hongying Chen, Junjie Li, Qiang Huang, Melanie J. Gupte, Hao Liu, Yueming Song, Zhishen Ge

BIOMATERIALS   52   1 - 13   2015.6

Polyplex Micelles with Thermoresponsive Heterogeneous Coronas for Prolonged Blood Retention and Promoted Gene Transfection Reviewed

Yang Li, Junjie Li, Biao Chen, Qixian Chen, Guoying Zhang, Shiyong Liu, Zhishen Ge

BIOMACROMOLECULES   15 ( 8 )   2914 - 2923   2014.8