Cellular characterization of hiPS CMs cultured on PMEA analogous polymers with different bound water content Reviewed

Hiroko Kurita, Shingo Kobayashi, Takahisa Anada, Masaru Tanaka, Mitsugu Todo

45 ( 1 )   1 - 6   2023.9

特定健診の質問表における咀嚼状態の都道府県差とその要因の検討

宮野 貴士, 穴田 貴久, 古田 美智子, 山下 喜久

口腔衛生学会雑誌   73 ( 2 )   103 - 111   2023.4   （ ISSN:0023-2831 ）

Simple Detection and Culture of Circulating Tumor Cells from Colorectal Cancer Patients Using Poly(2-Methoxyethyl Acrylate)-Coated Plates

Masatoshi Nomura, Yuhki Yokoyama, Daishi Yoshimura, Yasuhisa Minagawa, Aki Yamamoto, Yukiko Tanaka, Naoko Sekiguchi, Daiki Marukawa, Momoko Ichihara, Hiroaki Itakura, Kenichi Matsumoto, Yoshihiro Morimoto, Hideo Tomihara, Akira Inoue, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Hidenori Takahashi, Mamoru Uemura, Shogo Kobayashi, Tsunekazu Mizushima, Takahisa Anada, Masaki Mori, Yuichiro Doki, Masaru Tanaka, Hidetoshi Eguchi, Hirofumi Yamamoto

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   24 ( 4 )   2023.2

Cell Adhesion Strength Indicates the Antithrombogenicity of Poly(2-methoxyethyl acrylate) (PMEA): Potential Candidate for Artificial Small-Diameter Blood Vessel

Md Azizul Haque, Daiki Murakami, Masaru Tanaka

Surfaces   5 ( 3 )   365 - 382   2022.7

Poly(2-Methoxyethyl Acrylate) (PMEA)-Coated Anti-Platelet Adhesive Surfaces to Mimic Native Blood Vessels through HUVECs Attachment, Migration, and Monolayer Formation

Md Azizul Haque, Daiki Murakami, Takahisa Anada, Masaru Tanaka

Coatings   12 ( 6 )   2022.6

Octacalcium phosphate crystals including a higher density dislocation improve its materials osteogenecity. Reviewed International journal

R Hamai, S Sakai, Y Shiwaku, T Anada, K Tsuchiya, T Ishimoto, T Nakano, O Suzuki

Applied Materials Today   26   2021.11

Protein Stabilization Effect of Zwitterionic Osmolyte-bearing Polymer Reviewed International journal

R. Anjum, S. Nishimura, S. Kobayashi, K. Nishida, T. Anada, M. Tanaka

Chemistry Letters   50 ( 9 )   1699 - 1702   2021.7

Attachment and Growth of Fibroblast Cells on Poly(2-methoxyethyl acrylate) Analog Polymers as Coating Materials. Invited Reviewed International journal

R. Anjum, K. Nishida, H. Matsumoto, D. Murakami, S. Kobayashi, T. Anada, M. Tanaka

Coatings   11 ( 4 )   461 - 477   2021.4

Impact of simultaneous hydrolysis of OCP and PLGA on bone induction of a PLGA-OCP composite scaffold in a rat femoral defect. Invited Reviewed International journal

I Oizumi, R Hamai, Y Shiwaku, Y Mori, T Anada, K Baba, N Miyatake, S Hamada, K Tsuchiya, S Nishimura, E Itoi, O Suzuki

Acta Biomater   124   358 - 373   2021.2

Effect of surface modification of Ti-6Al-4V alloy by electron resonance plasma oxidation. Invited Reviewed International journal

M Oikawa, H Masumoto, N Shiraishi, Y Orii, T Anada, O Suzuki, K Sasaki

Dent Mater J   40   228 - 234   2021.1

Chemical stability-sensitive osteoconductive performance of octacalcium phosphate bone substitute in an ovariectomized rat tibia defect. Reviewed International journal

K Baba, Y Shiwaku, R Hamai, Y Mori, T Anada, K Tsuchiya, I Oizumi, N Miyatake, E Itoi, O Suzuki.

ACS Appl Bio Mater   ３   1444 - 1458   2020.2

Angiogenesis involvement by octacalcium phosphate-gelatin composite-driven bone regeneration in rat calvaria critical-sized defect Reviewed

Tsuyoshi Kurobane, Yukari Shiwaku, Takahisa Anada, Ryo Hamai, Kaori Tsuchiya, Kazuyoshi Baba, Masahiro Iikubo, Tetsu Takahashi, Osamu Suzuki

Acta Biomaterialia   88   514 - 526   2019.4

Culture of hybrid spheroids composed of calcium phosphate materials and mesenchymal stem cells on an oxygen-permeable culture device to predict in vivo bone forming capability Reviewed

Tomoya Sato, Takahisa Anada, Ryo Hamai, Yukari Shiwaku, Kaori Tsuchiya, Susumu Sakai, Kazuyoshi Baba, Keiichi Sasaki, Osamu Suzuki

Acta Biomaterialia   88   477 - 490   2019.4

Vascularized bone-mimetic hydrogel constructs by 3D bioprinting to promote osteogenesis and angiogenesis Reviewed

Takahisa Anada, Chi Chun Pan, Alexander M. Stahl, Satomi Mori, Junji Fukuda, Osamu Suzuki, Yunzhi Yang

International journal of molecular sciences   20 ( 5 )   2019.3

Histomorphometric assessments of peri-implant bone around Ti-Nb-Sn alloy implants with low Young's mosulus. Reviewed International journal

N Shiraishi, H Masumoto, K Takahashi, T Tenkumo, T Anada, O Suzuki, T Ogawa, K Sasaki.

Dent Mater J   in press   2019.3

Effect of functionally-Graded Calcium titanate film, prepared by metal-organic chemical vapor deposition, on titanium implant Reviewed

Naru Shiraishi, Risa Ishiko-Uzuka, Kenta Takahashi, Toru Ogawa, Takahisa Anada, Osamu Suzuki, Takashi Goto, Keiichi Sasaki

Applied Sciences (Switzerland)   9 ( 1 )   2019.1

Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling Reviewed

Hiroaki Ayabe, Takahisa Anada, Takuo Kamoya, Tomoya Sato, Masaki Kimura, Emi Yoshizawa, Shunyuu Kikuchi, Yasuharu Ueno, Keisuke Sekine, J. Gray Camp, Barbara Treutlein, Autumn Ferguson, Osamu Suzuki, Takanori Takebe, Hideki Taniguchi

Stem Cell Reports   11 ( 2 )   306 - 316   2018.8

Surface reactivity of octacalcium phosphate-derived fluoride-containing apatite in the presence of polyols and fluoride Reviewed

Sei Tsutsui, Takahisa Anada, Yukari Shiwaku, Kaori Tsuchiya, Hajime Yamazaki, Osamu Suzuki

Journal of Biomedical Materials Research - Part B Applied Biomaterials   106 ( 6 )   2235 - 2244   2018.8

Osteogenic cellular activity around onlaid octacalcium phosphate-gelatin composite onto rat calvaria Reviewed

Ryosuke Iwama, Takahisa Anada, Yukari Shiwaku, Kaori Tsuchiya, Tetsu Takahashi, Osamu Suzuki

Journal of Biomedical Materials Research - Part A   106 ( 5 )   1322 - 1333   2018.5

Capacity of octacalcium phosphate to promote osteoblastic differentiation toward osteocytes in vitro Reviewed

Yuko Sai, Yukari Shiwaku, Takahisa Anada, Kaori Tsuchiya, Tetsu Takahashi, Osamu Suzuki

Acta Biomaterialia   69   362 - 371   2018.3

Effect of polyols on phosphorus-containing calcium fluoride deposition on hydroxyapatite surfaces Reviewed

Sei Tsutsui, Takahisa Anada, Yukari Shiwaku, Atsushi Yamagishi, Osamu Suzuki

Journal of Hard Tissue Biology   27 ( 1 )   34 - 38   2018.1

Oriented bone regenerative capacity of octacalcium phosphate/gelatin composites obtained through two-step crystal preparation method Reviewed

Risa Ishiko-Uzuka, Takahisa Anada, Kazuhito Kobayashi, Tadashi Kawai, Yuji Tanuma, Keiichi Sasaki, Osamu Suzuki

Journal of Biomedical Materials Research - Part B Applied Biomaterials   105 ( 5 )   1029 - 1039   2017.7

Application of an indicator-immobilized-gel-sheet for measuring the pH surrounding a calcium phosphate-based biomaterial Reviewed

Taisuke Masuda, Hisataka Maruyama, Fumihito Arai, Takahisa Anada, Kaori Tsuchiya, Toshio Fukuda, Osamu Suzuki

Journal of Biomaterials Applications   31 ( 9 )   1296 - 1304   2017.4

Effect of resorption rate and osteoconductivity of biodegradable calcium phosphate materials on the acquisition of natural bone strength in the repaired bone Reviewed

Shinpei Chiba, Takahisa Anada, Kentaro Suzuki, Keisuke Saito, Yukari Shiwaku, Naohisa Miyatake, Kazuyoshi Baba, Hideki Imaizumi, Masami Hosaka, Eiji Itoi, Osamu Suzuki

Journal of Biomedical Materials Research - Part A   104 ( 11 )   2833 - 2842   2016.11

An oxygen-permeable spheroid culture chip (Oxy chip) promotes osteoblastic differentiation of mesenchymal stem cells Reviewed

Takuo Kamoya, Takahisa Anada, Yukari Shiwaku, Teruko Takano-Yamamoto, Osamu Suzuki

Sensors and Actuators, B: Chemical   232   75 - 83   2016.9

Comparative study on the resorbability and dissolution behavior of octacalcium phosphate, β-tricalcium phosphate, and hydroxyapatite under physiological conditions Reviewed

35 ( 2 )   216 - 224   2016.3

Evaluation of bioactivity of octacalcium phosphate using osteoblastic cell aggregates on a spheroid culture device Reviewed

Takahisa Anada, Tomoya Sato, Takuo Kamoya, Yukari Shiwaku, Kaori Tsuchiya, Teruko Takano-Yamamoto, Keiichi Sasaki, Osamu Suzuki

Regenerative Therapy   3   58 - 62   2016.3

A 3D culture model study monitoring differentiation of dental epithelial cells into ameloblast-like cells Reviewed

Mayu Tadaki, Takahisa Anada, Yukari Shiwaku, Takashi Nakamura, Masanori Nakamura, Masaru Kojima, Tatsuo Arai, Satoshi Fukumoto, Osamu Suzuki

RSC Advances   6 ( 67 )   62109 - 62118   2016.1

Bone matrix calcification during embryonic and postembryonic rat calvarial development assessed by SEM–EDX spectroscopy, XRD, and FTIR spectroscopy Reviewed

34 ( 1 )   41 - 50   2016.1

Immune cell response and subsequent bone formation induced by implantation of octacalcium phosphate in a rat tibia defect Reviewed

Bunichi Hirayama, Takahisa Anada, Yukari Shiwaku, Naohisa Miyatake, Kaori Tsuchiya, Masanori Nakamura, Tetsu Takahashi, Osamu Suzuki

RSC Advances   6 ( 62 )   57475 - 57484   2016.1

Dose-dependent enhancement of octacalcium phosphate biodegradation with a gelatin matrix during bone regeneration in a rabbit tibial defect model Reviewed

Keisuke Saito, Takahisa Anada, Yukari Shiwaku, Shinpei Chiba, Naohisa Miyatake, Kentaro Suzuki, Kaori Tsuchiya, Osamu Suzuki

RSC Advances   6 ( 69 )   64165 - 64174   2016.1

Enhancement of osteoblastic differentiation in alginate gel beads with bioactive octacalcium phosphate particles Reviewed

Kosei Endo, Takahisa Anada, Masumi Yamada, Minoru Seki, Keiichi Sasaki, Osamu Suzuki

Biomedical Materials (Bristol)   10 ( 6 )   2015.12

Orthotopic Osteogenecity Enhanced by a Porous Gelatin Sponge in a Critical-Sized Rat Calvaria Defect Reviewed

Naofumi Kanda, Takahisa Anada, Takuto Handa, Kazuhito Kobayashi, Yushi Ezoe, Tetsu Takahashi, Osamu Suzuki

Macromolecular Bioscience   15 ( 12 )   1647 - 1655   2015.12

Synthetic octacalcium phosphate-enhanced reparative dentine formation via induction of odontoblast differentiation Reviewed

Xiaogu Wang, Tetsuo Suzawa, Tomohiko Miyauchi, Baohong Zhao, Rika Yasuhara, Takahisa Anada, Masanori Nakamura, Osamu Suzuki, Ryutaro Kamijo

Journal of Tissue Engineering and Regenerative Medicine   9 ( 11 )   1310 - 1320   2015.11

Chondroitin Sulfate-E Binds to Both Osteoactivin and Integrin αvβ3 and Inhibits Osteoclast Differentiation Reviewed

116 ( 10 )   2247 - 2257   2015.10

The role of an octacalcium phosphate in the re-formation of infraspinatus tendon insertion Reviewed

Yoshiaki Itoigawa, Osamu Suzuki, Hirotaka Sano, Takahisa Anada, Takuto Handa, Taku Hatta, Yoshiyuki Kuwahara, Atsushi Takahashi, Yushi Ezoe, Kazuo Kaneko, Eiji Itoi

Journal of Shoulder and Elbow Surgery   24 ( 7 )   e175 - e184   2015.7

Effect of mechanical stress on differentiation of mouse mesenchymal stem cells seeded into an octacalcium phosphate-gelatin scaffold Reviewed

Masakazu Yamada, Takahisa Anada, Taisuke Masuda, Teruko Takano-Yamamoto, Osamu Suzuki

Sensors and Actuators, B: Chemical   220   125 - 130   2015.6

Biomechanical evaluation of Ti-Nb-Sn alloy implants with a low young’s modulus Reviewed

16 ( 3 )   5779 - 5788   2015.3

Characterization of partially hydrolyzed OCP crystals deposited in a gelatin matrix as a scaffold for bone tissue engineering Reviewed

Yushi Ezoe, Takahisa Anada, Hajime Yamazaki, Takuto Handa, Kazuhito Kobayashi, Tetsu Takahashi, Osamu Suzuki

Journal of Nanoparticle Research   17 ( 3 )   2015.1

Bone response to immediate loading through titanium implants with different surface roughness in rats Reviewed

Naoko Sato, Toshie Kuwana, Miou Yamamoto, Hanako Suenaga, Takahisa Anada, Shigeto Koyama, Osamu Suzuki, Keiichi Sasaki

Odontology   102 ( 2 )   249 - 258   2014.1

Osteoconductive property of a mechanical mixture of octacalcium phosphate and amorphous calcium phosphate Reviewed

Kazuhito Kobayashi, Takahisa Anada, Takuto Handa, Naofumi Kanda, Mariko Yoshinari, Tetsu Takahashi, Osamu Suzuki

ACS Applied Materials and Interfaces   6 ( 24 )   22602 - 22611   2014.1

Osteoblastic differentiation of stromal ST-2 cells from octacalcium phosphate exposure via p38 signaling pathway Reviewed

Ryuhei Nishikawa, Takahisa Anada, Risa Ishiko-Uzuka, Osamu Suzuki

Dental Materials Journal   33 ( 2 )   242 - 251   2014.1

Effect of mechanical stress on bone formation by osteoconductive octacalcium phosphate bone substitute materials Reviewed

Osamu Suzuki, Takahisa Anada, Taisuke Masuda

BME = Bio medical engineering / henshu, Nihon ME Gakkai   52   SY - 43   2014.1

Effect of addition of hyaluronic acids on the osteoconductivity and biodegradability of synthetic octacalcium phosphate Reviewed

Kentaro Suzuki, Takahisa Anada, Tatsuya Miyazaki, Naohisa Miyatake, Yoshitomo Honda, Koshi N. Kishimoto, Masami Hosaka, Hideki Imaizumi, Eiji Itoi, Osamu Suzuki

Acta Biomaterialia   10 ( 1 )   531 - 543   2014.1

Compressive force-produced CCN2 induces osteocyte apoptosis through ERK1/2 pathway Reviewed

Kenji Hoshi, Harumi Kawaki, Ichiro Takahashi, Nobuo Takeshita, Masahiro Seiryu, Sakhr A. Murshid, Taisuke Masuda, Takahisa Anada, Ryushi Kato, Hideki Kitaura, Osamu Suzuki, Teruko Takano-Yamamoto

Journal of Bone and Mineral Research   29 ( 5 )   1244 - 1257   2014.1

Characterization and bioactivity of nano-submicro octacalcium phosphate/gelatin composite Reviewed

Kei Ichiro Miura, Takahisa Anada, Yoshitomo Honda, Yukari Shiwaku, Tadashi Kawai, Seishi Echigo, Tetsu Takahashi, Osamu Suzuki

Applied Surface Science   282   138 - 145   2013.10

Labile Zn ions on octacalcium phosphate-derived Zn-containing hydroxyapatite surfaces Reviewed

Yoshitomo Honda, Takahisa Anada, Shinji Morimoto, Osamu Suzuki

Applied Surface Science   273   343 - 348   2013.5

Octacalcium phosphate suppresses chondrogenic differentiation of ATDC5 cells Reviewed

Isao Shibuya, Kentaro Yoshimura, Yoichi Miyamoto, Atsushi Yamada, Masamichi Takami, Tetsuo Suzawa, Dai Suzuki, Noriharu Ikumi, Fumitaka Hiura, Takahisa Anada, Osamu Suzuki, Ryutaro Kamijo

Cell and tissue research   352 ( 2 )   401 - 412   2013.5

Size regulation of chondrocyte spheroids using a PDMS-based cell culture chip Reviewed

Takahisa Anada, Osamu Suzuki

Journal of Robotics and Mechatronics   25 ( 4 )   644 - 649   2013.1

Structural, morphological and surface characteristics of two types of octacalcium phosphate-derived fluoride-containing apatitic calcium phosphates Reviewed

Y. Shiwaku, Takahisa Anada, H. Yamazaki, Y. Honda, S. Morimoto, K. Sasaki, O. Suzuki

Acta Biomaterialia   8 ( 12 )   4417 - 4425   2012.12

An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids Reviewed

Takahisa Anada, Junji Fukuda, Yuko Sai, Osamu Suzuki

Biomaterials   33 ( 33 )   8430 - 8441   2012.11

Biomechanical evaluation of amorphous calcium phosphate coated TNTZ implants prepared using a radiofrequency magnetron sputtering system Reviewed

Naru Shiraishi, Rong Tu, Risa Uzuka, Takahisa Anada, Takayuki Narushima, Takashi Goto, Mitsuo Niinomi, Keiichi Sasaki, Osamu Suzuki

Materials Transactions   53 ( 7 )   1343 - 1348   2012.10

A microfabricated platform to form three-dimensional toroidal multicellular aggregate Reviewed

Taisuke Masuda, Natsuki Takei, Takuma Nakano, Takahisa Anada, Osamu Suzuki, Fumihito Arai

Biomedical Microdevices   14 ( 6 )   1085 - 1093   2012.9

Granule size-dependent bone regenerative capacity of octacalcium phosphate in collagen matrix Reviewed

Yuji Tanuma, Takahisa Anada, Yoshitomo Honda, Tadashi Kawai, Shinji Kamakura, Seishi Echigo, Osamu Suzuki

Tissue Engineering - Part A   18 ( 5-6 )   546 - 557   2012.3

The effect of an octacalcium phosphate co-precipitated gelatin composite on the repair of critical-sized rat calvarial defects Reviewed

T. Handa, Takahisa Anada, Y. Honda, H. Yamazaki, K. Kobayashi, N. Kanda, S. Kamakura, S. Echigo, O. Suzuki

Acta Biomaterialia   8 ( 3 )   1190 - 1200   2012.3

Comparative study on in vitro biocompatibility of synthetic octacalcium phosphate and calcium phosphate ceramics used clinically Reviewed

Shinji Morimoto, Takahisa Anada, Yoshitomo Honda, Osamu Suzuki

Biomedical Materials (Bristol)   7 ( 4 )   2012.1

Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals Reviewed

Hirofumi Kaneko, Junichi Kamiie, Hirotaka Kawakami, Takahisa Anada, Yoshitomo Honda, Naru Shiraishi, Shinji Kamakura, Tetsuya Terasaki, Hidetoshi Shimauchi, Osamu Suzuki

Analytical Biochemistry   418 ( 2 )   276 - 285   2011.11

Characteristics of hydroxyapatite film formed on human enamel with the powder jet deposition technique Reviewed

Ryo Akatsuka, Keiichi Sasaki, Mohammed Saeed Sepasy Zahmaty, Miyoko Noji, Takahisa Anada, Osamu Suzuki, Tsunemoto Kuriyagawa

Journal of Biomedical Materials Research - Part B Applied Biomaterials   98 B ( 2 )   210 - 216   2011.8

Synergistic effects of micro/nano modifications on electrodes for microfluidic electrochemical ELISA Reviewed

Sonthaya Numthuam, Takahiro Kakegawa, Takahisa Anada, Ali Khademhosseini, Hiroaki Suzuki, Junji Fukuda

Sensors and Actuators, B: Chemical   156 ( 2 )   637 - 644   2011.8

Reconstruction of Critical-Sized Bone Defect in Dog Skull by Octacalcium Phosphate Combined with Collagen Reviewed

Tadashi Kawai, Keiko Matsui, Shinya Iibuchi, Takahisa Anada, Yoshitomo Honda, Kazuo Sasaki, Shinji Kamakura, Osamu Suzuki, Seishi Echigo

Clinical Implant Dentistry and Related Research   13 ( 2 )   112 - 123   2011.6

Effect of Zn2+ on the physicochemical characteristics of octacalcium phosphate and its hydrolysis into apatitic phases Reviewed

Yoshitomo Honda, Takahisa Anada, Shinji Morimoto, Yukari Shiwaku, Osamu Suzuki

Crystal Growth and Design   11 ( 5 )   1462 - 1468   2011.5

Evaluation of osteoclastic resorption activity using calcium phosphate coating combined with labeled polyanion Reviewed

Tatsuya Miyazaki, Satoshi Miyauchi, Takahisa Anada, Hideki Imaizumi, Osamu Suzuki

Analytical Biochemistry   410 ( 1 )   7 - 12   2011.3

The effect of synthetic octacalcium phosphate in a collagen scaffold on the osteogenicity of mesenchymal stem cells Reviewed

Tadashi Kawai, Takahisa Anada, Taisuke Masuda, Yoshitomo Honda, Yuhiro Sakai, Yukio Kato, Shinji Kamakura, Seishi Echigo, Osamu Suzuki

European Cells and Materials   22   124 - 136   2011.1

Effect of chondroitin sulfate-E on the osteoclastic differentiation of RAW264 cells Reviewed

Tatsuya Miyazaki, Satoshi Miyauchi, Akira Tawada, Takahisa Anada, Osamu Suzuki

dental materials journal   29 ( 4 )   403 - 410   2010.12

Quality of regenerated bone enhanced by implantation of octacalcium phosphate-collagen composite Reviewed

Taisuke Masuda, Tadashi Kawai, Takahisa Anada, Shinji Kamakura, Osamu Suzuki

Tissue Engineering - Part C: Methods   16 ( 3 )   471 - 478   2010.6

Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation Reviewed

Yusuke Orii, Hiroshi Masumoto, Yoshitomo Honda, Takahisa Anada, Takashi Goto, Keiichi Sasaki, Osamu Suzuki

Journal of Biomedical Materials Research - Part B Applied Biomaterials   93 ( 2 )   476 - 483   2010.5

Three-dimensional cell culture device utilizing thin membrane deformation by decompression Reviewed

Takahisa Anada, Taisuke Masuda, Yoshitomo Honda, Junji Fukuda, Fumihito Arai, Toshio Fukuda, Osamu Suzuki

Sensors and Actuators, B: Chemical   147 ( 1 )   376 - 379   2010.5

Comparative study on bone regeneration by synthetic octacalcium phosphate with various granule sizes Reviewed

Yoshihisa Murakami, Yoshitomo Honda, Takahisa Anada, Hidetoshi Shimauchi, Osamu Suzuki

Acta Biomaterialia   6 ( 4 )   1542 - 1548   2010.4

Preparation and characterization of porous alginate scaffolds containing various amounts of octacalcium phosphate (OCP) crystals Reviewed

Naru Shiraishi, Takahisa Anada, Yoshitomo Honda, Taisuke Masuda, Keiichi Sasaki, Osamu Suzuki

Journal of Materials Science: Materials in Medicine   21 ( 3 )   907 - 914   2010.3

Analysis of physicochemical properties of octacalcium phosphate prepared by hydrolysis and co-precipitation with fluoride ions Reviewed

Yukari Shiwaku, Yoshitomo Honda, Takahisa Anada, Shinji Morimoto, Taisuke Masuda, Keiichi Sasaki, Osamu Suzuki

Journal of the Ceramic Society of Japan   118 ( 1378 )   402 - 405   2010.1

Mechanical stress-related calvaria bone augmentation by onlayed octacalcium phosphate-collagen implant Reviewed

Aritsune Matsui, Takahisa Anada, Taisuke Masuda, Yoshitomo Honda, Naohisa Miyatake, Tadashi Kawai, Shinji Kamakura, Seishi Echigo, Osamu Suzuki

Tissue Engineering - Part A   16 ( 1 )   139 - 151   2010.1

Appositional bone formation by OCP-Collagen composite Reviewed

Y. Suzukfi, S. Kamakura, Y. Honda, Takahisa Anada, K. Hatori, K. Sasaki, O. Suzuki

Journal of Dental Research   88 ( 12 )   1107 - 1112   2009.12

Osteoclast differentiation induced by synthetic octacalcium phosphate through receptor activator of NF-κB ligand expression in osteoblasts Reviewed

15 ( 12 )   3991 - 4000   2009.12

Octacalcium phosphate-precipitated alginate scaffold for bone regeneration Reviewed

Takeshi Fuji, Takahisa Anada, Yoshitomo Honda, Yukari Shiwaku, Hiroko Koike, Shinji Kamakura, Keiichi Sasaki, Osamu Suzuki

Tissue Engineering - Part A   15 ( 11 )   3525 - 3535   2009.11

Molecular mechanisms of mechanical stress response during chondrogenesis Reviewed

Ichiro Takahashi, Taisuke Masuda, Kumiko Kohsaka, Fumie Terao, Takahisa Anada, Yasuyuki Sasano, Teruko Takano-Yamamoto, Osamu Suzuki

Journal of Biomechanical Science and Engineering   4 ( 3 )   307 - 317   2009.9

Synthesis of calcium phosphate-binding liposome for drug delivery Reviewed

Takahisa Anada, Yoichi Takeda, Yoshitomo Honda, Kazuo Sakurai, Osamu Suzuki

Bioorganic and Medicinal Chemistry Letters   19 ( 15 )   4148 - 4150   2009.8

The effect of microstructure of octacalcium phosphate on the bone regenerative property Reviewed

Yoshitomo Honda, Takahisa Anada, Shinji Kamakura, Shinji Morimoto, Tsunemoto Kuriyagawa, Osamu Suzuki

Tissue Engineering - Part A   15 ( 8 )   1965 - 1973   2009.8

Effect of partial hydrolysis of octacalcium phosphate on its osteoconductive characteristics Reviewed

Naohisa Miyatake, Koshi N. Kishimoto, Takahisa Anada, Hideki Imaizumi, Eiji Itoi, Osamu Suzuki

Biomaterials   30 ( 6 )   1005 - 1014   2009.2

Synthetic octacalcium phosphate augments bone regeneration correlated with its content in collagen scaffold Reviewed

Tadashi Kawai, Takahisa Anada, Yoshitomo Honda, Shinji Kamakura, Keiko Matsui, Aritsune Matsui, Kazuo Sasaki, Shinji Morimoto, Seishi Echigo, Osamu Suzuki

Tissue Engineering - Part A   15 ( 1 )   23 - 32   2009.1

Intramembranous bone reaction to synthetic ocp during hydroxyapatite deposition onto the OCP template

Osamu Suzuki, Tazunu Kikawa, Takahisa Anada, Shinji Kamakura, Hideki Imaizumi

8th World Biomaterials Congress 2008, WBC 2008 8th World Biomaterials Congress 2008   1   2008.12

Oversulfated chondroitin sulfate-E binds to BMP-4 and enhances osteoblast differentiation Reviewed

Tatsuya Miyazaki, Satoshi Miyauchi, Akira Tawada, Takahisa Anada, Satoshi Matsuzaka, Osamu Suzuki

Journal of cellular physiology   217 ( 3 )   769 - 777   2008.12

Dose-dependent osteogenic effect of octacalcium phosphate on mouse bone marrow stromal cells Reviewed

Takahisa Anada, Takashi Kumagai, Yoshitomo Honda, Taisuke Masuda, Ryutaro Kamijo, Shinji Kamakura, Nobuhito Yoshihara, Tsunemoto Kuriyagawa, Hidetoshi Shimauchi, Osamu Suzuki

Tissue Engineering - Part A.   14 ( 6 )   965 - 978   2008.6

Development of a cell culture system loading cyclic mechanical strain to chondrogenic cells Reviewed

Taisuke Masuda, Ichiro Takahashi, Takahisa Anada, Fumihito Arai, Toshio Fukuda, Teruko Takano-Yamamoto, Osamu Suzuki

Journal of Biotechnology   133 ( 2 )   231 - 238   2008.1

Delivery of antisense oligonucleotides to nuclear telomere RNA by use of a complex between polysaccharide and polynucleotide Reviewed

Jusaku Minari, Takanori Kubo, Hideki Ohba, Naohiko Shimada, Yoich Takeda, Ryouji Karinaga, Takahisa Anada, Kazuya Koumoto, Takeshi Kawazu, Takeshi Nagasaki, Seiji Shinkai, Kazuo Sakurai

Bulletin of the Chemical Society of Japan   80 ( 6 )   1091 - 1098   2007.12

The primacy of octacalcium phosphate collagen composites in bone regeneration Reviewed

Shinji Kamakura, Kazuo Sasaki, Takahiro Homma, Yoshitomo Honda, Takahisa Anada, Seishi Echigo, Osamu Suzuki

Journal of Biomedical Materials Research - Part A   83 ( 3 )   725 - 733   2007.11

Dehydrothermal treatment of collagen influences on bone regeneration by octacalcium phosphate (OCP) collagen composites Reviewed

Shinji Kamakura, Kazuo Sasaki, Yoshitomo Honda, Takahisa Anada, Keiko Matsui, Seishi Echigo, Osamu Suzuki

Journal of Tissue Engineering and Regenerative Medicine   1 ( 6 )   450 - 456   2007.9

A polysaccharide carrier to effectively deliver native phosphodiester CpG DNA to antigen-presenting cells Reviewed

Naohiko Shimada, Cevayir Coban, Yoichi Takeda, Masami Mizu, Jusaku Minari, Takahisa Anada, Yuichi Torii, Seiji Shinkai, Shizuo Akira, Ken J. Ishii, Kazuo Sakurai

Bioconjugate Chemistry   18 ( 4 )   1280 - 1286   2007.7

Octacalcium phosphate combined with collagen orthotopically enhances bone regeneration Reviewed

Shinji Kamakura, Kazuo Sasaki, Yoshitomo Honda, Takahisa Anada, Osamu Suzuki

Journal of Biomedical Materials Research - Part B Applied Biomaterials   79 ( 2 )   210 - 217   2006.11

Elevated extracellular calcium stimulates secretion of bone morphogenetic protein 2 by a macrophage cell line Reviewed

Yoshitomo Honda, Takahisa Anada, Shinji Kamakura, Masanori Nakamura, Shunji Sugawara, Osamu Suzuki

Biochemical and Biophysical Research Communications   345 ( 3 )   1155 - 1160   2006.7

CpG DNA/zymosan complex to enhance cytokine secretion owing to the cocktail effect Reviewed

Takahisa Anada, Naoko Okada, Jusaku Minari, Ryouji Karinaga, Masami Mizu, Kazuya Koumoto, Seiji Shinkai, Kazuo Sakurai

Bioorganic and Medicinal Chemistry Letters   16 ( 5 )   1301 - 1304   2006.3

Galactose-PEG dual conjugation of β-(1→3)-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake Reviewed

27 ( 8 )   1626 - 1635   2006.3

Cholesterol-appended β-(1→3)-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake Reviewed

78 ( 10 )   1821 - 1830   2005.12

Linear double-stranded DNA that mimics an infective tail of virus genome to enhance transfection Reviewed

Takahisa Anada, Ryouji Karinaga, Kazuya Koumoto, Masami Mizu, Takeshi Nagasaki, Yoshio Kato, Kazunari Taira, Seiji Shinkai, Kazuo Sakurai

Journal of Controlled Release   108 ( 2-3 )   529 - 539   2005.11

PEG-appended β-(1→3)-D-glucan schizophyllan to deliver antisense-oligonucleotides with avoiding lysosomal degradation Reviewed

26 ( 23 )   4866 - 4873   2005.8

Competition between polysaccharide/polynucleotide complexation vs., polynucleotide hybridization; salt concentration dependence of the reaction direction Reviewed

Ryouji Karinaga, Kazuya Koumoto, Jusaku Minari, Masami Mizu, Takahisa Anada, Kazuo Sakurai, Seiji Shinkai

e-Journal of Surface Science and Nanotechnology   3   38 - 45   2005.2

A new polynucleotide-polysaccharide complex and its application to functional oligonucleotide delivery Reviewed

Takahisa Anada, Kazuo Sakurai, Seiji Shinkai

Trends in Glycoscience and Glycotechnology   17 ( 94 )   49 - 57   2005.1

Removal of the side-chain glucose groups from schizophyllan improves the thermal stability of the polycytidylic acid complexes under the physiological conditions Reviewed

Kazuya Koumoto, Ryouji Karinaga, Masami Mizu, Takahisa Anada, Kazuo Sakurai, Toyoki Kunitake, Seiji Shinkai

Biopolymers   75 ( 5 )   403 - 411   2004.12

First observation by fluorescence polarization of complexation between mRNA and the natural polysaccharide schizophyllan Reviewed

Ryouji Karinaga, Masami Mizu, Kazuya Koumoto, Takahisa Anada, Seiji Shinkai, Taro Kimura, Kazuo Sakurai

Chemistry and Biodiversity   1 ( 4 )   634 - 639   2004.12

Proposal of new modification technique for linear double-stranded DNAs using the polysaccharide schizopyllan Reviewed

Takahisa Anada, Hideshi Matsunaga, Ryouji Karinaga, Kazuya Koumoto, Masami Mizu, Koji Nakano, Seiji Shinkai, Kazuo Sakurai

Bioorganic and Medicinal Chemistry Letters   14 ( 22 )   5655 - 5659   2004.11

A polysaccharide carrier for immunostimulatory CpG DNAs to enhance cytokine secretion Reviewed

Masami Mizu, Kazuya Koumoto, Takahisa Anada, Takahiro Matsumoto, Munenori Numata, Seiji Shinkai, Takeshi Nagasaki, Kazuo Sakurai

Journal of the American Chemical Society   126 ( 27 )   8372 - 8373   2004.7

Enhancement of the antisense effect of polysaccharide-polynucleotide complexes by preventing the antisense oligonucleotide from binding to proteins in the culture medium Reviewed

Masami Mizu, Kazuya Koumoto, Takahisa Anada, Ryouji Karinaga, Taro Kimura, Takeshi Nagasaki, Seiji Shinkai, Kazuo Sakurai

Bulletin of the Chemical Society of Japan   77 ( 6 )   1101 - 1110   2004.6

Chemically modified polysaccharide schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake efficiency Reviewed

Takahiro Matsumoto, Munenori Numata, Takahisa Anada, Masami Mizu, Kazuya Koumoto, Kazuo Sakurai, Takeshi Nagasaki, Seiji Shinkai

Biochimica et Biophysica Acta - General Subjects   1670 ( 2 )   91 - 104   2004.1

Antisense oligonucleotides bound in the polysaccharide complex and the enhanced antisense effect due to the low hydrolysis Reviewed

Masami Mizu, Kazuya Koumoto, Takahisa Anada, Kazuo Sakurai, Seiji Shinkai

Biomaterials   25 ( 15 )   3117 - 3123   2004.1

Microanalysis of Nucleic Acids Using the Limulus G Test Reviewed

Takahisa Anada, Kazuya Koumoto, Masami Mizu, Ryouji Karinaga, Kazuo Sakurai, Seiji Shinkai

Analytical Sciences   19 ( 12 )   1567 - 1568   2003.12

Novel DNA/polymer conjugate for intelligent antisense reagent with improved nuclease resistance Reviewed

Masaharu Murata, Wataru Kaku, Takahisa Anada, Yoshikuni Sato, Takeshi Kano, Mizuo Maeda, Yoshiki Katayama

Bioorganic and Medicinal Chemistry Letters   13 ( 22 )   3967 - 3970   2003.11

Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate Reviewed

Masaharu Murata, Wataru Kaku, Takahisa Anada, Yoshikuni Sato, Mizuo Maeda, Yoshiki Katayama

Chemistry Letters   32 ( 11 )   986 - 987   2003.11

Thermo responsive DNA/polymer conjugate for intelligent antisense strategy Reviewed

Masaharu Murata, Wataru Kaku, Takahisa Anada, Nobuaki Soh, Yoshiki Katayama, Mizuo Maeda

Chemistry Letters   32 ( 3 )   266 - 267   2003.3

Oligodeoxynucleotide-modified capillary for electrophoretic separation of single-stranded DNAs with a single-base difference Reviewed

Takahisa Anada, Masako Ogawa, Hisashi Yokomizo, Yoshihisa Ozaki, Tohru Takarada, Yoshiki Katayama, Mizuo Maeda

Analytical Sciences   19 ( 1 )   73 - 77   2003.1

The separation of oligodeoxynucleotides having a single-base difference by affinity capillary electrophoresis using oligodeoxynucleotide-polyacrylamide conjugate Reviewed

Takahisa Anada, Takumi Arisawa, Yoshihisa Ozaki, Tohru Takarada, Yoshiki Katayama, Mizuo Maeda

Electrophoresis   23 ( 14 )   2267 - 2273   2002.7

New fluorescent "off-on" behavior of 9-anthryl aromatic amides through controlling the twisted intramolecular charge transfer relaxation process by complexation with metal ions Reviewed

Tatsuya Morozumi, Takahisa Anada, Hiroshi Nakamura

Journal of Physical Chemistry B   105 ( 15 )   2923 - 2931   2001.4

Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration

Osamu Suzuki, Takahisa Anada

Springer Japan  2015.1 

「アンチエージングシリーズ３・骨研究最前線」リン酸八カルシウム（OCP）を用いる次世代バイオマテリアルの開発

鈴木治，穴田貴久（ Role： Joint author）

エヌ・ティー・エス  2013.10 

Bone regeneration by octacalcium phosphate and collagen composites

Shinji Kamakura, Takahisa Anada, Osamu Suzuki

Nova Science Publishers, Inc.  2010.1 

歯科再生医学

穴田貴久, 鈴木 治

医歯薬出版株式会社 

日本農芸化学会

新規表面修飾技術を応用した強力な骨固着高分子コーティングスクリューの開発

2021 - 2023

日本学術振興会  科学研究費助成事業  基盤研究(C)

細胞内液滴を標的とする高分子医薬

2020

AMED橋渡し研究戦略的推進プログラム・シーズA

骨誘導性セラミックス骨補填材の開発

2018 - 2020

日本学術振興会  科学研究費助成事業  基盤研究(B)

三次元酸素濃度勾配培養による骨発生機序の再構築

2017 - 2019

日本学術振興会  科学研究費助成事業  挑戦的研究（萌芽）

ゲル転写共培養法による厚みのある複合組織体作製と応用

2017 - 2019

日本学術振興会  科学研究費助成事業  基盤研究(B)

有機-無機共沈法で免疫関連タンパク質を集積する硬組織再生材料の開発

2017 - 2018

日本学術振興会  科学研究費助成事業  挑戦的研究（萌芽）

骨芽細胞活性化能を有する生体内分解性骨片接合材の開発

2016 - 2019

日本学術振興会  科学研究費助成事業  基盤研究(C)

骨芽細胞活性化能を有する生体内分解性骨片接合材の開発

2016 - 2018

日本学術振興会  科学研究費助成事業  基盤研究(C)

専門英語（個別テーマ）

2022.10 - 2023.3   Second semester

物質科学工学実験第三

2022.10 - 2023.3   Second semester

身の回りの化学

2022.6 - 2022.8   Summer quarter

分子生命工学演習第八

2022.4 - 2023.3   Full year

安全学（生体材料）

2022.4 - 2022.9   First semester

再生医工材料学

2022.4 - 2022.9   First semester

身の回りの化学

2022.4 - 2022.6   Spring quarter

物質科学工学実験第三

2021.10 - 2022.3   Second semester

身の回りの化学

2021.6 - 2021.8   Summer quarter

安全学（生体材料）

2021.4 - 2021.9   First semester

再生医工材料学

2021.4 - 2021.9   First semester

身の回りの化学

2021.4 - 2021.6   Spring quarter

物質科学工学実験第三

2020.10 - 2021.3   Second semester

専門英語

2020.10 - 2021.3   Second semester

再生医工材料学

2020.10 - 2021.3   Second semester

物質科学工学概論第二

2020.10 - 2021.3   Second semester

身の回りの化学

2020.6 - 2020.8   Summer quarter

安全学（生体材料）

2020.4 - 2020.9   First semester

身の回りの化学

2020.4 - 2020.6   Spring quarter

医療材料設計学

2019.10 - 2020.3   Second semester

学術英語３・個別テーマ（技術英語）

2019.10 - 2020.3   Second semester

安全学（生体材料）

2019.4 - 2019.9   First semester

不明

一般財団法人 化学物質評価研究機構（ＣＥＲＩ） 寄付講座  2019.10

化学への招待「生き物から化学を学んでみよう！」

日本化学会九州支部  2019.8