Updated on 2024/07/28

Information

 

写真a

 
AKASAKI YUKIO
 
Organization
Kyushu University Hospital Orthopedic Surgery Lecturer
School of Medicine Department of Medicine(Joint Appointment)
Title
Lecturer
Contact information
メールアドレス
Profile
Surgecal and pharmacological treatment for knee joint disorders and rhuematoid arthritis Research on the pathogenesis and treatment of osteoarthritis and the surgical treatment for knee joint disorders

Degree

  • Doctor of Medical Science

Research Interests・Research Keywords

  • Research theme:Interlocking open-wedge Distal tibial Tuberosity Osteotomy: Stabilizing technique in the Retro-tubercle without complementary Screw Fixation

    Keyword:IL-DTO

    Research period: 2023.4

  • Research theme:UKA in a super-aging society

    Keyword:UKA, super-aging society

    Research period: 2021.4

  • Research theme:Promotion of Knee Cartilage Degradation by IκB Kinase ε in the Pathogenesis of Osteoarthritis in Human and Murine Models

    Keyword:IKKε

    Research period: 2020.4 - 2024.6

  • Research theme:C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis

    Keyword:DEPP

    Research period: 2019.4 - 2022.3

  • Research theme:GRK5 inhibition as a new therapeutic target for osteoarthritis

    Keyword:GRK5

    Research period: 2018.4

  • Research theme:Activation of FOXO transcription factor for inhibition of cartilage degradation

    Keyword:FOXO transcription factor

    Research period: 2015.4

  • Research theme:Transthyretin and Amyloid deposition in osteoarthritis

    Keyword:Amyloid Transthyretin

    Research period: 2015.4

  • Research theme:The anti-inflammtory effects of intra-articularly injected statins on osteoarthritis

    Keyword:statins intra-articular osteoarthritis anti-inflammation

    Research period: 2009.4

Awards

  • 第22回日本軟骨代謝学会賞

    2017.3   日本軟骨代謝学会   FOXO転写因子は、活性酸素分解酵素とオートファジー関連蛋白を制御し、軟骨細胞の酸化ストレス抵抗を維持する

  • 九州大学整形外科研究奨励賞(骨々賞)

    2008.11   九州大学整形外科学教室   スタチンの関節内投与による変形性関節症進行予防

  • New Investigator Recognition Award (NIRA)

    2008.3   54th Annual Meeting of the Orthopaedic Research Society  

Papers

  • Interlocking Open-Wedge Distal Tibial Tuberosity Osteotomy: Stabilizing Technique in the Retro-Tubercle Without Complementary Screw Fixation Reviewed International journal

    Yukio Akasaki, Tomohiro Horikawa, Satoshi Hamai, Shinya Kawahara, Taishi Sato, Yasuharu Nakashima

    Arthroscopy Techniques   2024.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Promotion of Knee Cartilage Degradation by IκB Kinase ε in the Pathogenesis of Osteoarthritis in Human and Murine Models Reviewed International journal

    2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Similar Short-Term KOOS Between Open-Wedge High Tibial Osteotomy and Total Knee Arthroplasty in Patients Over Age 60: A Propensity Score-Matched Cohort Study Reviewed International journal

    Sakai M, Akasaki Y, Akiyama T, Horikawa T, Okazaki K, Hamai S, Tsushima H, Kawahara S, Kurakazu I, Kubota K, Mizu-Uchi H, Nakashima Y

    Mod Rheumatol. 2023 Apr 13;33(3):623-628.   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Fluvastatin promotes chondrogenic differentiation of adipose-derived mesenchymal stem cells by inducing bone morphogenetic protein 2 Reviewed International journal

    Kuwahara M, Akasaki Y, Goto N, Kurakazu I, Sueishi T, Toya M, Uchida T, Tsutsui T, Hirose R, Tsushima H, Nakashima Y.

    BMC Pharmacology and Toxicology. 23(1):61. 2022   2022.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  • C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis Reviewed International journal

    Kuwahara M, Akasaki Y, Kurakazu I, Sueishi T, Toya M, Uchida T, Tsutsui T, Hirose R, Tsushima H, Teramura T, Nakashima Y.

    FASEB J.   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  • G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis Reviewed International journal

    Toya M, Akasaki Y, Sueishi T, Kurakazu I, Kuwahara M, Uchida T, Tsutsui T, Tsushima H, Yamada H, Lotz MK, Nakashima Y.

    Scientific Reports   2021.5

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  • Angular accuracy of plain radiographic measurements in leg alignment: Teleoroentgenogram versus orthoroentgenogram Reviewed International journal

    Takakura K, Akasaki Y, Kuramoto T, Onizuka Y, Hattori A, Hamai S, Tsushima H, Kawahara S, Nakashima Y, Kato T.

    J Orthop Sci.   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  • TGFβ1 signaling protects chondrocytes against oxidative stress via FOXO1–autophagy axis. Reviewed International journal

    2021.5

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  • Transverse osteotomy closer to tibial plateau is associated with larger postoperative change in valgus laxity after open-wedge high tibial osteotomy Reviewed International journal

    Soejima Y, Akasaki Y, Hamai S, Tsushima H, Kawahara S, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc.   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Morphological changes affecting ipsilateral and contralateral leg alignment after total hip arthroplasty Reviewed International journal

    Akasaki Y, Kitade K, Motomura G, Hamai S, Ikemura S, Fujii M, Kawahara S, Nakashima Y.

    J Orthop   2020.12

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  • Distal tuberosity osteotomy in open-wedge high tibial osteotomy does not exacerbate patellofemoral osteoarthritis on arthroscopic evaluation. Reviewed International journal

    Horikawa T, Kubota K, Hara S, Akasaki Y.

    Knee Surg Sports Traumatol Arthrosc   2020.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  • GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signalling. Reviewed International journal

    2020.4

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  • The influence of post-operative knee coronal alignment parameters on long-term patient-reported outcomes after closed-wedge high tibial osteotomy. Invited Reviewed International journal

    Goto N, Akasaki Y, Okazaki K, Kuwashima U, Iwasaki K, Kawamura H, Mizu-Uchi H, Hamai S, Tsushima H, Kawahara S, Nakashima Y.

    J Orthop   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Patient-specific prediction of joint line convergence angle after high tibial osteotomy using a whole-leg radiograph standing on lateral-wedge insole. Reviewed International journal

    Akasaki Y, Mizu-Uchi H, Hamai S, Tsushima H, Kawahara S, Horikawa T, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc   2019.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  • FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling. Reviewed International journal

    2019.11

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Transthyretin deposition in articular cartilage: A novel mechanism in the pathogenesis of osteoarthritis. Reviewed International journal

    Yukio Akasaki, Reixach N, Matsuzaki T, Alvarez-Garcia O, Olmer M, Yukihide Iwamoto, Buxbaum JN, Lotz MK

    Arthritis and Rheumatology   2015.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  • A simple predictive formula for the blood requirement in patients with high-energy blunt injuries transferred within one hour post-trauma.

    Yukio Akasaki, Hiroshi Sugimori, MOMII KENTA, Tomohiko Akahoshi, Matsuura Suguru, Yukihide Iwamoto, Yoshihiko Maehara, Makoto Hashizume

    Acute Medicine & Surgery   2015.4

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    Language:English  

  • FoxO Transcription Factors Support Oxidative Stress Resistance in Human Chondrocytes. Reviewed International journal

    Arthritis and Rheumatology   2014.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. Reviewed International journal

    Yukio Akasaki, Hasegawa A, Saito M, Asahara H, Yukihide Iwamoto, Lotz MK

    Osteoarthritis and Cartilage   2014.1

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Total knee arthroplasty following failed high tibial osteotomy: mid-term comparison of posterior cruciate-retaining versus posterior stabilized prosthesis Reviewed International journal

    Akasaki Y, Matsuda S, Miura H, Okazaki K, Moro-Oka TA, Mizu-Uchi H, Iwamoto Y

    Knee Surgery Sports Traumatology Arthroscopy   2009.5

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  • Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation Reviewed International journal

    Akasaki Y, Matsuda S, Nakayama K, Fukagawa S, Miura H, Iwamoto Y

    Osteoarthritis and Cartilage.   2009.2

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  • Contact stress analysis of the conforming post-cam mechanism in posterior-stabilized total knee arthroplasty Reviewed International journal

    Akasaki Y, Matsuda S, Shimoto T, Miura H, Higaki H, Iwamoto Y

    Journal of Arthroplasty   2008.8

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  • Synovial-tissue resident macrophages play proinflammatory functions in the pathogenesis of RA while maintaining the phenotypes in the steady state Reviewed International journal

    Kai K, Yamada H, Tsurui R, Sakuraba K, Fujimura K, Kawahara S, Akasaki Y, Tsushima H, Fujiwara T, Hara D, Fukushi JI, Sawa S, Nakashima Y.

    Immunol Med.2024 Jan 3:1-10.   2024.1

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  • Interaction between functional capability and sleep quality at midterm after total knee arthroplasty: a Japanese retrospective cohort study Reviewed International journal

    Hamai S, Harada S, Tsushima H, Kozuma R, Yamate S, Kawahara S, Akasaki Y, Harada T, Kokubu Y, Konishi T, Nakashima Y.

    Sci Rep.2023 Oct 26;13(1):18373.   2023.10

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  • "Grand-piano sign" as a femoral rotational indicator in both varus and valgus knees: a simulation study of anterior resection surface in total knee arthroplasty Reviewed International journal

    Kokubu Y, Kawahara S, Hamai S, Akasaki Y, Tsushima H, Miyachika S, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc. 2023 Aug;31(8):3259-3267.   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritis Reviewed International journal

    Ohzono H, Hu Y, Nagira K, Kanaya H, Okubo N, Olmer M, Gotoh M, Kurakazu I, Akasaki Y, Kawata M, Chen E, Chu AC, Johnson KA, Lotz MK

    Ann Rheum Dis. 2023 Feb;82(2):262-271.   2023.3

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  • Is there a reduction in hip destruction under a treat-to-target strategy in patients with rheumatoid arthritis? Reviewed International journal

    Tsushima H, Takahide S, Akasaki Y, Fujiwara T, Hara D, Ikemura S, Sakuraba K, Kamura S, Miyahara H, Yamada H, Fukushi JI, Nakashima Y.

    Mod Rheumatol. 2023 Feb 14:road021   2023.2

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  • Preoperative Virtual Total Knee Arthroplasty Surgery Using a Computed Tomography-based 3-dimensional Model With Variation in Reference Points and Target Alignment to Predict Femoral Component Sizing Reviewed International journal

    Ishibashi S, Mizu-Uchi H, Kawahara S, Tsushima H, Akasaki Y, Nakashima Y

    Arthroplast Today. 17:27-35. 2022   2022.6

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  • Smaller femoral neck anteversion in varus knees than in healthy and valgus knees Invited Reviewed International journal

    Kawahara S, Hara D, Murakami K, Hamai S, Akasaki Y, Tsushima H, Banks SA, Nakashima Y.

    Clin Anat. 35(8):1044-1050. 2022   2022.6

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  • Sagittal femoral bowing contributes to distal femoral valgus angle deviation in malrotated preoperative radiographs Invited Reviewed International journal

    Kokubu Y, Kawahara S, Hamai S, Akasaki Y, Tsushima H, Momii K, Nakashima Y

    BMC Musculoskelet Disord. 23(1):579. 2022   2022.6

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  • Improved surgical procedure of primary constrained total knee arthroplasty which enables use of the femoral diaphyseal straight extension stem Invited Reviewed International journal

    Kawahara S, Mawatari T, Matsui G, Hamai S, Akasaki Y, Tsushima H, Nakashima Y

    BMC Musculoskelet Disord. 23(1):408. 2022   2022.6

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  • Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry Reviewed International journal

    Fujiwara T, Kondo M, Yamada H, Haraguchi A, Fujimura K, Sakuraba K, Kamura S, Fukushi JI, Miyahara H, Inoue Y, Tsuru T, Shuto T, Yoshizawa S, Suematsu E, Miyamura T, Ayano M, Mitoma H, Arinobu Y, Niiro H, Ohishi M, Hirata A, Tokunaga S, Takada A, Hara D, Tsushima H, Akasaki Y, Ikemura S, Sueishi T, Toya M, Sakuragi T, Tsutsui T, Kai K, Arisumi S, Nakashima Y.

    Arthritis Res Ther. 24(1):53. 2022   2022.6

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  • Frequency and risk factor analyses of bone erosion of the distal interphalangeal joint in patients with rheumatoid arthritis: a cross-sectional study Reviewed International journal

    Ikemura S, Hagio S, Akasaki Y, Fujiwara T, Tsushima H, Nakashima Y.

    Acta Reumatol Port.   2021.5

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  • Autoreactivity of Peripheral Helper T Cells in the Joints of Rheumatoid Arthritis Reviewed International journal

    Sakuragi T, Yamada H, Haraguchi A, Kai K, Fukushi JI, Ikemura S, Akasaki Y, Fujiwara T, Tsushima H, Tsutsui T, Kondo M, Yoshikai Y, Okada S, Nakashima Y.

    J Immunol.   2021.5

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  • Effect of osteoarthritis severity on survival and clinical outcomes after high tibial osteotomy Reviewed International journal

    Kuwashima U, Iwasaki K, Kurakazu I, Akasaki Y, Nakashima Y, Itoh M, Itou J, Okazaki K.

    Knee   2021.3

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  • Axial But Not Sagittal Hinge Axis Affects Posterior Tibial Slope in Medial Open-wedge High Tibial Osteotomy: A Three-dimensional Surgical Simulation Study Reviewed International journal

    Teng Y, Mizu-Uchi H, Xia Y, Akasaki Y, Akiyama T, Kawahara S, Nakashima Y.

    Arthroscopy   2021.2

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  • Prognostic factors for the short-term mortality of patients with rheumatoid arthritis admitted to intensive care units Reviewed International journal

    Fujiwara T, Tokuda K, Momii K, Shiomoto K, Tsushima H, Akasaki Y, Ikemura S, Fukushi JI, Maki J, Kaku N, Akahoshi T, Taguchi T, Nakashima Y.

    BMC Rheumatol   2020.12

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  • Malrotation of whole-leg radiograph less than 10 degrees does not influence preoperative planning in open-wedge high tibial osteotomy Reviewed International journal

    Kawahara S, Mawatari T, Matsui G, Mizu-Uchi H, Hamai S, Akasaki Y, Tsushima H, Nakashima Y.

    J Orthop Res   2020.9

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  • Does Preparation of the Subtalar Joint for Primary Union Affect Clinical Outcome in Patients Undergoing Intramedullary Nail for Rheumatoid Arthritis of the Hindfoot and Ankle? Reviewed International journal

    Yoshimoto K, Fukushi JI, Tsushima H, Kamura S, Miyahara HA, Mizu-Uchi H, Akasaki Y, Nakashima Y.

    J Foot Ankle Surg. 59(5):984-987. 2020   2020.4

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  • Patient reported outcomes after high tibial osteotomy show comparable results at different ages in the mid-term to long-term follow-up. Reviewed International journal

    Kuwashima U, Okazaki K, Iwasaki K, Akasaki Y, Kawamura H, Mizu-Uchi H, Hamai S, Nakashima Y.

    J Orthop Sci. 2019 Jan 11.   2018.12

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  • In vivo kinematics of gait in posterior-stabilized and bicruciate-stabilized total knee arthroplasties using image-matching techniques. Reviewed International journal

    Murakami K, Hamai S, Okazaki K, Wang Y, Ikebe S, Higaki H, Shimoto T, Mizu-Uchi H, Akasaki Y, Nakashima Y.

    Int Orthop. 42(11):2573-2581. 2018   2018.12

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  • Knee kinematics in bi-cruciate stabilized total knee arthroplasty during squatting and stair-climbing activities. Reviewed International journal

    Murakami K, Hamai S, Okazaki K, Gondo H, Wang Y, Ikebe S, Higaki H, Shimoto T, Mizu-Uchi H, Akasaki Y, Nakashima Y.

    J Orthop. 15(2):650-654. 2018   2018.12

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  • Bony landmarks with tibial cutting surface are useful to avoid rotational mismatch in total knee arthroplasty. Reviewed International journal

    Ma Y, Mizu-Uchi H, Ushio T, Hamai S, Akasaki Y, Murakami K, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1570-1579.   2018.12

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  • Medial soft tissue contracture does not always exist in varus osteoarthritis knees in total knee arthroplasty. Reviewed International journal

    Ushio T, Mizu-Uchi H, Okazaki K, Miyama K, Akasaki Y, Ma Y, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1642-1650.   2018.12

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  • Recreational sports, workout and gym activities after total knee arthroplasty: Asian cohort study. Reviewed International journal

    Matsushita Y, Hamai S, Okazaki K, Murakami K, Ma Y, Kiyohara M, Mizu-Uchi H, Akasaki Y, Nakashima Y.

    J Orthop. 16(1):41-44. 2018   2018.12

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  • Degenerative changes in cartilage likely occur in the medial compartment after anterior cruciate ligament reconstruction. Reviewed International journal

    Ushio T, Okazaki K, Osaki K, Takayama Y, Sagiyama K, Mizu-Uchi H, Hamai S, Akasaki Y, Honda H, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc. 2019 Mar 16.   2018.12

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  • Alignment factors affecting the medial meniscus extrusion increases the risk of osteoarthritis development. Reviewed International journal

    Goto N, Okazaki K, Akiyama T, Akasaki Y, Mizu-Uchi H, Hamai S, Nakamura S, Nakashima Y.

    Knee Surg Sports Traumatol Arthrosc. 2018 Nov 19.   2018.12

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  • FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis. Reviewed International journal

    Matsuzaki T, Alvarez-Garcia O, Mokuda S, Nagira K, Olmer M, Gamini R, Miyata K, Akasaki Y, Su AI, Asahara H, Lotz MK.

    Sci Transl Med. 14;10(428). 2018   2018.3

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  • Effects of tibial baseplate shape on rotational alignment in total knee arthroplasty: three-dimensional surgical simulation using osteoarthritis knees. Reviewed International journal

    Ma Y, Mizu-Uchi H, Okazaki K, Ushio T, Murakami K, Hamai S, Akasaki Y, Nakashima Y.

    Arch Orthop Trauma Surg. 138(1):105-114. 2018   2018.1

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  • Anterior cruciate ligament reconstruction in a patient who has received systemic steroids for autoimmune disease. Reviewed International journal

    Ushio T, Okazaki K, Mizu-Uchi H, Hamai S, Akasaki Y, Nakashima Y.

    Asia Pac J Sports Med Arthrosc Rehabil Technol. 5;11:12-14. 2017   2017.6

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  • A single intra-articular injection of fluvastatin-PLGA microspheres reduces cartilage degradation in rabbits with experimental osteoarthritis. Reviewed International journal

    Goto N, Okazaki K, Akasaki Y, Ishihara K, Murakami K, Koyano K, Ayukawa Y, Yasunami N, Masuzaki T, Nakashima Y.

    J Orthop Res. 35(11):2465-2475. 2017   2017.6

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  • Three-dimensional analysis of accuracy of patient-matched instrumentation in total knee arthroplasty: Evaluation of intraoperative techniques and postoperative alignment. Reviewed International journal

    Kuwashima U, Mizu-Uchi H, Okazaki K, Hamai S, Akasaki Y, Murakami K, Nakashima Y.

    J Orthop Sci. 22(6):1077-1083. 2017   2017.6

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  • Transthyretin deposition promotes progression of osteoarthritis. Reviewed International journal

    Matsuzaki T, Akasaki Y, Olmer M, Alvarez-Garcia O, Reixach N, Buxbaum JN, Lotz MK.

    Aging Cell. 16(6):1313-1322. 2017   2017.6

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  • Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis. Reviewed International journal

    Yamada H, Haraguchi A, Sakuraba K, Okazaki K, Fukushi JI, Mizu-Uchi H, Akasaki Y, Esaki Y, Kamura S, Fujimura K, Kondo M, Miyahara H, Nakashima Y, Yoshikai Y.

    RMD Open. 13;3(1):e000487. 2017   2017.6

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  • Minimum 10-year results of cementless total hip arthroplasty in patients with rheumatoid arthritis. Reviewed International journal

    Haraguchi A, Nakashima Y, Miyahara H, Esaki Y, Okazaki K, Fukushi JI, Hirata G, Ikemura S, Kamura S, Sakuraba K, Fujimura K, Akasaki Y, Yamada H.

    Mod Rheumatol. 27(4):598-604. 2017   2017.4

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  • Characterisation of osteophytes as an autologous bone graft source: An experimental study in vivo and in vitro. Reviewed International journal

    Ishihara K, Okazaki K, Akiyama T, Yukio Akasaki, Yasuharu Nakashima

    Bone Joint Res   2017.2

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  • Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage. Reviewed International journal

    Hasegawa A, Yonezawa T, Taniguchi N, Otabe K, Yukio Akasaki, Matsukawa T, Saito M, Neo M, Marmorstein LY, Lotz MK

    Arthritis and Rheumatology   2017.1

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  • Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy. Reviewed International journal

    Alvarez-Garcia O, Olmer M, Akagi R, Yukio Akasaki, Fisch KM, Shen T, Su AI, Lotz MK

    Osteoarthritis and Cartilage   2016.4

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  • In Vivo Kinematics of Healthy and Osteoarthritic Knees During Stepping Using Density-Based Image-Matching Techniques. Reviewed International journal

    Hamai S, Okazaki K, Ikebe S, Murakami K, Higaki H, Nakahara H, Shimoto T, Mizu-Uchi H, Yukio Akasaki, Yukihide Iwamoto

    J Appl Biomech   2016.3

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  • Outcome of Joint-Preserving Arthroplasty for Rheumatoid Forefoot Deformities. Reviewed International journal

    Jun-ichi Fukushi, Yasuharu Nakashima, Okazaki K, Yamada H, Mawatari T, Ohishi M, Oyamada A, Yukio Akasaki, Yukihide Iwamoto

    Foot & Ankle International   2016.3

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  • Contact stress analysis of the anterior tibial post in bi-cruciate stabilized and mobile-bearing posterior stabilized total knee arthroplasty designs. Reviewed International journal

    Kuwashima U, Hamai S, Okazaki K, Ikebe S, Higaki H, Mizu-Uchi H, Yukio Akasaki, Murakami K, Yukihide Iwamoto

    J Mech Behav Biomed Mater   2016.3

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  • Delayed diagnosis of ankylosing spondylitis in a Japanese population. Reviewed International journal

    Yasuharu Nakashima, Ohishi M, Okazaki K, Jun-ichi Fukushi, Oyamada A, Hara D, Doi T, Yukio Akasaki, Yamada H, Yukihide Iwamoto

    Modern Rheumatology   2016.1

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  • Glucosamine activates autophagy in vitro and in vivo. Reviewed International journal

    Arthritis and Rheumatology   2013.6

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  • The evaluation of post-operative alignment in total knee replacement using a CT-based navigation system. Reviewed International journal

    Mizu-uchi H, Matsuda S, Miura H, Okazaki K, Akasaki Y, Iwamoto Y

    Journal of Bone and Joint Surgery British   2008.8

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Books

  • [膝周囲骨切り術]内側開大式粗面下脛骨骨切り術 新OS NEXUS 膝関節の再建手術

    赤崎幸穂

    2022.6 

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    Language:Japanese  

  • [総論:治療法]手術療法・関節鏡視下手術 膝関節外科学

    赤崎幸穂

    2021.6 

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    Language:Japanese  

  • [総論:検査・周術期管理]Ⅰ 術前 1.体位と術野の準備 ⑥大腿骨骨折 整形外科Knack&Pitfalls 整形外科手術の要点と盲点

    赤崎幸穂

    2011.6 

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  • [各論:個別のテクニック]Ⅰ 感染症 1.開放創の処置 整形外科Knack&Pitfalls 整形外科手術の要点と盲点

    赤崎幸穂

    2011.6 

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    Language:Japanese  

Presentations

  • IκB kinase ε(IKKε) inhibition attenuates cartilage degradation by regulating NF-κB signaling International conference

    2023.2 

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    Event date: 2024.4

    Language:Japanese  

    Country:United States  

  • RA患者クラスター分析からみえる層別化医療の展望 - FRANK registry-

    赤崎幸穂, 近藤正一, 山田久方, 宮原寿明, 福士純一, 井上靖, 都留智巳, 首藤敏秀, 吉澤誠司, 宮村知也,新納宏昭, 綾野雅宏, 大石正信, 加茂健太, 前山彰, 藤原稔史, 津嶋秀俊, 原大介, 平田明恵, 中島康晴

    第65回九州リウマチ学会  2023.3 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • NF-κB経路を制御する新規OA標的(GRK5とIKKε)と既存薬(アンレキサノクス)によるOA新薬開発

    赤崎幸穂, 内田泰輔, 居石卓也, 廣瀬良太, 兵藤裕貴, 境真未子, 中島康晴

    第38回日本整形外科学会基礎学術集会  2023.10 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • インターロッキングOW-DTO:前後スクリュー固定を必要としない粗面下骨切りの工夫

    赤崎幸穂、堀川朝広、秋山武徳

    第1回日本膝関節学会  2023.12 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 再生医療が応えるアンメットニーズは?

    赤崎幸穂

    第1回日本膝関節学会  2023.12 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • OW-DTO術後の脛骨後傾変化の特徴 ~従来法との比較~

    赤崎幸穂, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第143回西日本整形・災害外科学会  2022.6 

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    Event date: 2022.6

    Language:Japanese  

    Country:Japan  

  • The regulation of cartilage degradation by GRK-5 during osteoarthritis development International conference

    Takuya Sueishi, Yukio Akasaki, Norio Goto, Ichiro Kurakazu, Masakazu Toya, Masanari Kuwahara, Yasuharu Nakashima

    Orthopaedic Research Society 2019 Annual Meeting  2019.2 

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    Event date: 2019.2

    Language:English  

    Country:United States  

  • 外側楔状足底板を使用した術前立位Xpによる高位脛骨骨切り術後のJLCAの予測

    赤崎幸穂、水内秀城、牛尾哲郎

    第10回JOSKAS  2018.6 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変性軟骨組織におけるTransthyretin性アミロイド沈着の病態意義の検討

    赤崎幸穂、松本嘉寛、後藤徳雄、居石卓也、倉員市郎、遠矢正和、中島康晴

    第50回日本結合組織学会学術大会  2018.5 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Forkhead box O(FOXO)転写因子は、オートファジー関連蛋白を制御し、軟骨細胞の酸化ストレス抵抗を維持する

    赤崎幸穂、林田光正、後藤徳雄、倉員市郎、居石卓也、遠矢政和、中島康晴

    第91回日本整形外科学会学術総会  2018.5 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変形性膝関節症に対する高位脛骨骨切り術の手術時年齢が術後長期成績へ与える影響

    赤崎幸穂、福士純一、池村聡、後藤徳雄、倉員市郎、居石卓也、遠矢政和、岡崎賢、中島康晴

    第62回日本リウマチ学会学術集会  2018.4 

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    Event date: 2018.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Transthyretin and Amyloid deposition in Osteoarthritis International conference

    Yukio Akasaki, Martin K. Lotz, Tokio Matsuzaki, Oscar Alvarez-Garcia, KEN OKAZAKI, Yasuharu Nakashima

    The ORS 2017 Annual Meeting  2017.3 

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    Event date: 2017.3

    Language:English  

    Country:United States  

  • FOXO転写因子は、活性酸素分解酵素とオートファジー関連蛋白を制御し、軟骨細胞の酸化ストレス抵抗を維持する

    赤崎 幸穂, Oscar A. Garcia, 齊藤雅彦, Beatriz Carame´s, 岩本 幸英, Martin K. Lotz

    第30回日本軟骨代謝学会  2017.3 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • Transthyretin and amyloid in cartilage aging and osteoarthritis International conference

    Yukio Akasaki, Alvarez-Garcia O, Reixach N, Buxbaum JN, Yukihide Iwamoto, Lotz MK

    The 2015 Osteoarthritis Research Society International (OARSI) World Congress  2015.4 

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    Event date: 2015.5

    Language:English  

    Country:United States  

  • Clinical Results of PCL-Retaining TKA were inferior to PCL-Substituting TKA after Tibial Osteotomy International conference

    Yukio Akasaki; Shuichi Matsuda; Ken Okazaki; Yasutaka Tashiro; Hideki Mizu-uchi; Hiroaki Mitsuyasu; Yukihide Iwamoto

    2012 Annual Meeting of American Academy of Orthopaedic Surgeons  2011.2 

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    Event date: 2011.2

    Presentation type:Oral presentation (general)  

    Country:United States  

  • Statins prevent production of monocyte chemoattractant protein-1 and matrix-metalloproteinase-3 in IL-1β stimulated synoviocytes through inhibition of protein isoprenylation International conference

    2009.2 

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    Event date: 2009.2

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Las Vegas   Country:United States  

  • Statin prevents cartilage degradation and synovial inflammation in experimental osteoarthritis. International conference

    2008.3 

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    Event date: 2008.3

    Language:English   Presentation type:Oral presentation (general)  

    Venue:San Francisco   Country:United States  

  • Statin induces chondrogenic differentiation in bone marrow stromal cells. International conference

    Akasaki Y, Matsuda S, Nakayama K, Mizu-uchi H, Fukagawa S, Iwamoto Y.

    53th Annual Meeting of the Orthopaedic Research Society  2007.2 

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    Event date: 2007.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • Transthyretin and Amyloid in Cartilage Aging and Osteoarthritis. International conference

    Yukio Akasaki, Reixach N, Alvarez-Garcia O, Olmer M, Yukihide Iwamoto, Buxbaum J, Lotz MK

    The 2014 American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) Annual Meeting.  2014.11 

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    Country:United States  

  • The Effect of Intra-articularly Injected Statin on Cartilage Degradation and Synovial Inflammation in Experimental Osteoarthritis. International conference

    Yukio Akasaki, Shuichi Matsuda, Nakayama K, Fukagawa S, Mitsuyasu H, Hiromasa Miura, Yukihide Iwamoto

    The 7th Biennial ISAKOS Congress  2009.4 

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    Language:English  

    Country:Japan  

  • Inhibition of geranylgeranylation reduces MCP-1 production in IL-1β-stimulated human synoviocytes. International conference

    2012.2 

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    Venue:San Francisco, CA, USA   Country:United States  

  • Dysregulated FOXO Transcription Factors in Articular Cartilage in Aging and Osteoarthritis. International conference

    Yukio Akasaki, Liu-Bryan R, Terkeltaub R, Lotz M

    The 2013 Osteoarthritis Research Society International (OARSI) World Congress  2013.4 

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    Language:English  

    Country:United States  

  • Downregulated Forkhead-Box Class O Transcription Factors Attenuate Oxidative Stress Resistance In Human Chondrocytes. International conference

    Yukio Akasaki, Lotz M

    The 2013 American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) Annual Meeting  2013.10 

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    Country:United States  

  • 術前%MAが0%以下の症例に対するUKAの術後1年成績

    赤崎幸穂, 濵井敏, 川原慎也, 佐藤太志, 中島康晴

    第28回Fukuoka Knee Society  2023.10 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • IκB kinase ε(IKKε)は、NF-κB経路を介して軟骨変性を促進する

    内田泰輔,赤崎幸穂,居石卓也,遠矢政和,桑原正成,廣瀬良太,兵藤裕貴,津嶋秀俊,中島康晴

    第35回日本軟骨代謝学会  2023.3 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • OW-DTO術後の脛骨後傾変化の特徴 ~従来法との比較~

    赤崎幸穂, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第48回九州膝関節研究会  2023.3 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • OW-HTO後に外反laxityが増大する症例は、骨切り開始点が関節面寄りであった

    赤崎幸穂, 副島悠, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第96回日本整形外科学会学術総会  2023.5 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • UKA脛骨骨切り髄外ガイドの矢状面での術中設置について

    赤崎幸穂, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第145回西日本整形・災害外科学会学術集会  2023.6 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 患者クラスター分析からみえるRA外科介入の対象群 - FRANK registry-

    赤崎幸穂, 近藤正一, 宮原寿明, 福士純一, 大石正信, 前山彰, 藤原稔史, 原大介, 中島康晴

    第52回 日本リウマチの外科学会  2023.9 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 関節リウマチに対する人工膝関節単顆置換術(UKA)の是非の検証

    赤崎幸穂, 藤原稔史, 原大介, 山田久方, 濵井敏, 川原慎也, 佐藤太志, 中島康晴

    第66回九州リウマチ学会  2023.9 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • IκB kinase (IKK)およびTANK-binding kinase 1 (TBK1)の半月板変性に対する関与およびIKKε/TBK1阻害薬の治療効果についての検討

    廣瀬良太, 赤崎幸穂, 桑原正成, 内田泰輔, 兵藤裕貴, 津嶋秀俊,中島康晴

    第38回日本整形外科学会基礎学術集会  2023.10 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • UKA脛骨髄外ロッド設置時のデバイス使用とワンポイントnaviによるクロスチェックの有用性

    赤崎幸穂, 井上隆広, 濵井敏, 川原慎也, 佐藤太志, 中島康晴

    第146回西日本整形・災害外科学会学術集会  2023.11 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 早期荷重OW-DTO後の脛骨後傾変化の特徴 ~従来法との比較~

    赤崎幸穂, 濵井敏, 川原慎也, 佐藤太志, 中島康晴

    第1回日本膝関節学会  2023.12 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • 簡易デバイスを用いたUKA脛骨髄外ロッドの後傾角の任意設定

    赤崎幸穂, 濵井敏, 川原慎也, 佐藤太志, 中島康晴

    第1回日本膝関節学会  2023.12 

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    Event date: 2024.4

    Language:Japanese  

    Country:Japan  

  • IκB kinase ε(IKKε)阻害は、NF-κB経路を介して軟骨変性を抑制する

    内田泰輔,赤崎幸穂,居石卓也,倉員市郎,遠矢政和,桑原正成,廣瀬良太,津嶋秀俊,中島康晴

    第37回 日本整形外科学会基礎学術集会  2022.10 

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    Event date: 2022.10

    Language:Japanese  

    Country:Japan  

  • Propensity score matchingによる60歳以上の変形性膝関節症に対するHTOとTKAの臨床成績の比較

    堀川朝広, 赤崎幸穂, 秋山武徳, 岡崎賢, 久保田健治, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第2回 日本Knee Osteotomy and Joint Preservation研究会  2022.10 

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    Event date: 2022.10

    Language:Japanese  

    Country:Japan  

  • OW-HTOの期待・満足度に影響する因子の検討

    赤崎幸穂, 木原大護, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第2回 日本Knee Osteotomy and Joint Preservation研究会  2022.10 

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    Event date: 2022.10

    Language:Japanese  

    Country:Japan  

  • OW-DTO術後の脛骨後傾変化の特徴 ~従来法との比較~

    赤崎幸穂, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第2回 日本Knee Osteotomy and Joint Preservation研究会  2022.10 

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    Event date: 2022.10

    Language:Japanese  

    Country:Japan  

  • IκB kinase ε(IKKε)阻害薬は、NF-κB経路を介して軟骨変性を抑制し、OA治療薬候補となる

    内田泰輔,赤崎幸穂,居石卓也,倉員市郎,遠矢政和,桑原正成,廣瀬良太,兵藤裕貴,津嶋秀俊,中島康晴

    第2回 日本Knee Osteotomy and Joint Preservation研究会  2022.10 

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    Event date: 2022.10

    Language:Japanese  

    Country:Japan  

  • OW-HTO術後の満足度・期待度に影響する因子の検討

    木原大護, 赤崎幸穂, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第47回九州膝関節研究会  2022.7 

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    Event date: 2022.7

    Language:Japanese  

    Country:Japan  

  • Propensity score matchingによる60歳以上の変形性膝関節症に対するHTOとTKAの臨床成績の比較

    赤崎幸穂, 秋山武徳, 堀川朝広, 久保田健治, 境真未子, 濵井敏, 津嶋秀俊, 川原慎也, 水内秀城, 中島康晴

    第47回九州膝関節研究会  2022.7 

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    Event date: 2022.7

    Language:Japanese  

    Country:Japan  

  • 当院におけるRA膝に対するTKAの変遷と長期患者立脚評価

    倉員太志, 赤崎幸穂, 池村聡, 藤原稔史, 津嶋秀俊, 山田久方, 中島康晴

    第143回西日本整形・災害外科学会  2022.6 

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    Event date: 2022.6

    Language:Japanese  

    Country:Japan  

  • GRK5 Deletion Suppresses The Progression Of Inflammatory Arthritis In Mice. International conference

    Toya M, Akasaki Y, Tsushima H, Sueishi T, Kurakazu I, Kuwahara M, Uchida T, Nakashima Y

    The 2020 Annual Meeting of Orthopaedic Research Society  2021.2 

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    Event date: 2022.5

    Language:English  

    Country:Japan  

  • GRK5 (G protein-coupled receptor kinase 5)阻害は自然免疫細胞及び線維芽細胞様滑膜細胞を介して炎症性関節炎の発症・増悪を抑制する

    遠矢政和, 赤崎幸穂, 津嶋秀俊, 居石卓也, 倉員市郎, 桑原正成, 内田泰輔, 池村 聡, 藤原稔史, 山田久方, 中島康晴

    第65回 日本リウマチ学会総会・学術集会  2021.4 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 60歳以上の変形性膝関節症に対するHTOとTKAの短期臨床成績の比較

    境真未子,赤崎幸穂,秋山武徳,堀川朝広,岡崎 賢,濱井 敏,津嶋秀俊,川原慎也,中島康晴

    第141回西日本整形・災害外科学会  2021.5 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • OW-HTO前後における内側laxityの変化に影響する因子の検討

    副島 悠, 赤崎幸穂, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第141回西日本整形・災害外科学会  2021.5 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • GRK5 (G protein-coupled receptor kinase 5)阻害は自然免疫細胞及び線維芽細胞様滑膜細胞を介して炎症性関節炎の発症・増悪を抑制する

    遠矢政和, 赤崎幸穂, 津嶋秀俊, 居石卓也, 倉員市郎, 桑原正成, 内田泰輔, 筒井知明, 中島康晴

    第42回 日本炎症・再生医学会  2021.7 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • OW-HTOにおけるunder-correctionの要因の検討

    赤崎幸穂, 秋山武徳, 北 拓海, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第46回九州膝関節研究会  2021.7 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 60歳以上の変形性膝関節症に対するHTOとTKAの短期臨床成績の比較

    赤崎幸穂, 池村 聡, 藤原稔史, 津嶋秀俊, 原 大介, 中島康晴

    第50回日本リウマチ外科学会  2021.9 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • C10orf10/Decidual protein induced by progesterone (DEPP)はオートファジーフラックスを介して軟骨細胞の酸化ストレス抵抗性を維持する

    桑原正成, 赤崎幸穂, 倉員市郎, 居石卓也, 遠矢政和, 内田泰輔, 筒井知明, 津嶋秀俊, 中島康晴

    第36回 日本整形外科学会基礎学術集会  2021.10 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • OW-HTO術後の満足度・期待度に影響する因子の検討

    木原大護, 赤崎幸穂, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第26回Fukuoka Knee Society  2021.10 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 全下肢長尺撮影条件による下肢アライメント計測値の精度

    赤崎幸穂, 高倉健太, 鬼塚泰裕, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第26回Fukuoka Knee Society  2021.10 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 外側楔状足底板を使用した全下肢立位XpによるHTO後JLCA変化の患者ごとの術前予測

    赤崎幸穂, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第9回日本Knee Osteotomyフォーラム  2021.12 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • OW-HTO術後の満足度・期待度に影響する因子の検討

    木原大護, 赤崎幸穂, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第142回西日本整形・災害外科学会  2021.12 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 粗面下骨切りOW-HTO(DTO)の短期成績〜従来式OW-HTOとの比較〜

    副島 悠, 赤崎幸穂, 濵井 敏, 津嶋秀俊, 川原慎也, 有薗 剛, 中島康晴

    第142回西日本整形・災害外科学会  2021.12 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • 全下肢長尺撮影条件による下肢アライメント計測値の精度

    赤崎幸穂, 高倉健太, 鬼塚泰裕, 服部昭子, 倉本 卓, 加藤豊幸, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第1回日本Knee Osteotomy and Joint Preservation研究会  2021.12 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • GRK5 阻害薬は、NF-κB経路を介して軟骨変性を抑制し、OA治療薬候補となる

    赤崎幸穂, 居石卓也, 桑原正成, 内田泰輔, 筒井知明, 津嶋秀俊, Martin Lotz, 中島康晴

    第1回日本Knee Osteotomy and Joint Preservation研究会  2021.12 

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    Event date: 2022.5

    Language:Japanese  

    Country:Japan  

  • TGFβ-Alk5-Smad3 Signaling Promotes FOXO1 Expression And Protects Chondrocytes Against Oxidative Stress By Regulating Autophagy. International conference

    2021.2 

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    Event date: 2022.5

    Language:English  

    Country:Japan  

  • C10orf10/DEPPはミトコンドリアオートファジー活性化により変形性関節症病態における軟骨細胞生存を維持する

    桑原正成, 赤崎幸穂, 津嶋秀俊, 池村聡, 藤原稔史, 倉員市郎, 居石卓也, 遠矢政和, 内田泰輔, 廣瀬良太, 山田久方, 中島康晴

    第63回 九州リウマチ学会  2022.4 

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    Event date: 2022.4

    Language:Japanese  

    Country:Japan  

  • C10orf10/decidual protein induced by progesteroneの軟骨細胞における機能解析と変形性関節症の病態への関与

    桑原正成, 赤崎幸穂, 倉員市郎, 居石卓也, 遠矢政和, 内田泰輔, 筒井知明, 廣瀬良太, 津嶋秀俊, 中島康晴

    第66回 日本リウマチ学会総会・学術集会  2022.4 

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    Event date: 2022.4

    Language:Japanese  

    Country:Japan  

  • Propensity score matchingによる60歳以上の変形性膝関節症に対するHTOとTKAの臨床成績の比較

    堀川朝広, 赤崎幸穂, 秋山武徳, 岡崎賢, 久保田健治, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第66回 日本リウマチ学会総会・学術集会  2022.4 

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    Event date: 2022.4

    Language:Japanese  

    Country:Japan  

  • C10orf10/DEPP is a positive regulator of autophagy under stress conditions and maintains chondrocyte viability. International conference

    Kuwahara M, Akasaki Y, Kurakazu I, Sueishi T, Toya M, Uchida T, Tsutsui T, Hirose R, Tsushima H, Nakashima Y

    The 2022 Annual Meeting of Orthopaedic Research Society  2022.2 

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    Event date: 2022.2

    Language:English  

    Country:United States  

  • C10orf10/DEPPはミトコンドリアオートファジーを亢進させることで、軟骨細胞の酸化ストレス抵抗性を維持する

    桑原正成, 赤崎幸穂, 倉員市郎, 居石卓也, 遠矢政和, 内田泰輔, 筒井知明, 廣瀬良太, 津嶋秀俊, 中島康晴

    第34回日本軟骨代謝学会  2022.2 

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    Event date: 2022.2

    Language:Japanese  

    Country:Japan  

  • キナーゼX阻害は、NF-κBおよびC/EBPβの核内移行を制御して軟骨の変性を抑える

    内田泰輔,赤崎幸穂,居石卓也,遠矢政和,桑原正成,筒井知明,廣瀬良太,津嶋秀俊,中島康晴

    第34回日本軟骨代謝学会  2022.2 

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    Event date: 2022.2

    Language:Japanese  

    Country:Japan  

  • GRK5 (G protein-coupled receptor kinase 5) の阻害はNFκBシグナルの抑制を介して炎症性関節炎の進行を抑制する

    遠矢政和, 赤崎幸穂, 津嶋秀俊, 居石卓也, 桑原正成, 内田泰輔, 筒井知明, 池村 聡, 藤原稔史, 山田久方, 中島康晴

    第61回 九州リウマチ学会  2021.3 

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    Event date: 2021.3

    Language:Japanese  

    Country:Japan  

  • 外側楔状足底板を使用した高位脛骨骨切り術後JLCA変化の患者ごとの術前予測

    赤崎幸穂, 水内秀城, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第12回JOSKAS  2020.12 

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    Event date: 2020.12

    Language:Japanese  

    Country:Japan  

  • Fluvastatinはヒト脂肪由来間葉系幹細胞の軟骨分化を促進する

    桑原正成, 赤崎幸穂, 後藤徳雄, 津嶋秀俊, 倉員市郎, 居石卓也, 遠矢政和, 内田泰輔, 中島康晴

    第35回 日本整形外科学会基礎学術集会  2020.10 

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    Event date: 2020.10 - 2020.11

    Language:Japanese  

    Country:Japan  

  • 外側楔状足底板を使用した全下肢立位Xpによる患者特有のHTO前後JLCA変化の術前予測

    赤崎幸穂, 池村 聡, 藤原稔史, 津嶋秀俊, 山田久方, 中島康晴

    第64回 日本リウマチ学会総会・学術集会  2020.8 

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    Event date: 2020.8

    Language:Japanese  

    Country:Japan  

  • GRK5(G protein-coupled receptor kinase 5)阻害は炎症性関節炎の進行を抑制する

    遠矢政和, 赤崎幸穂, 津嶋秀俊, 居石卓也, 倉員市郎, 桑原正成, 内田泰輔, 池村 聡, 藤原稔史, 筒井智子, 山田久方, 中島康晴

    第64回 日本リウマチ学会総会・学術集会  2020.8 

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    Event date: 2020.8

    Language:Japanese  

    Country:Japan  

  • 外側楔状足底板を使用した全下肢立位XpによるHTO前後JLCA変化の術前予測

    赤崎幸穂, 水内秀城, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第47回日本関節病学会  2019.11 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • G protein-coupled receptor kinase (GRK)-5阻害は、NFκB経路の制御を介して変形性関節症における軟骨変性を抑制する

    居石卓也, 赤崎幸穂, 池村聡, 藤原稔史, 津嶋秀俊, 倉員市郎, 遠矢政和, 桑原正成, 内田泰輔, 中島康晴

    第83回九州リウマチ学会  2019.9 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • G protein-coupled receptor kinase (GRK)-5阻害は、NFκB経路の制御を介して変形性関節症における軟骨変性を抑制する

    居石卓也, 赤崎幸穂, 津嶋秀俊, 倉員市郎, 遠矢政和, 桑原正成, 内田泰輔, 中島康晴

    第37回日本骨代謝学会学術集会  2019.10 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • 炎症性関節炎の病態形成におけるGRK5(G protein-coupled receptor kinase 5)の機能解析

    遠矢 政和, 赤崎 幸穂, 津嶋 秀俊, 居石 卓也, 倉員 市郎, 桑原 正成, 内田 泰輔, 池村 聡, 藤原 稔史, 山田 久方, 中島 康晴

    第34回 日本整形外科学会基礎学術集会  2019.10 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • THA前後における下肢アライメント変化の影響因子:同側vs対側

    北出一季, 赤崎幸穂, 福士純一, 本村悟朗, 濵井敏, 池村聡, 藤井政徳, 山口亮介, 水内秀城, 中島康晴

    第139回西日本整形・災害外科学会  2019.6 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • 高位脛骨骨切り術後長期における患者立脚型評価不良例の検討

    赤崎幸穂, 岩崎賢優, 水内秀城, 川村秀哉

    第11回JOSKAS  2019.6 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • 先天性脊椎骨端異形成症による高度外反変形に対して、大腿骨遠位V字骨切り術を施行した1例

    赤崎幸穂

    第6回九州Knee Osteotomy研究会  2019.8 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • 当科における膝滑膜炎に対する関節鏡下滑膜切除術

    赤崎幸穂, 池村聡, 藤原稔史, 津嶋秀俊, 中島康晴

    第48回日本リウマチ外科学会  2019.9 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • 当科における粗面下遠位骨切りOWHTO術後の画像および関節鏡評価

    赤崎幸穂, 水内秀城, 濵井 敏, 津嶋秀俊, 川原慎也, 中島康晴

    第25回Fukuoka Knee Society  2019.11 

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    Event date: 2020.6

    Language:Japanese  

    Country:Japan  

  • GRK5 Deletion Suppresses The Progression Of Inflammatory Arthritis In Mice. International conference

    Toya M, Akasaki Y, Tsushima H, Sueishi T, Kurakazu I, Kuwahara M, Uchida T, Nakashima Y

    Orthopaedic Research Society 2020 Annual Meeting  2020.2 

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    Event date: 2020.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • インプラント設置後の大腿骨・脛骨骨切り面の位置関係を考慮した術中屈曲ギャップ評価

    赤崎幸穂, 水内秀城, 濵井敏, 津嶋秀俊, 川原慎也, 中島康晴

    第50回日本人工関節学会  2020.2 

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    Event date: 2020.2

    Language:Japanese  

    Country:Japan  

  • TGFβ-Alk5-Smad3 Signaling Promotes FOXO1 Expression And Protects Chondrocytes Against Oxidative Stress By Regulating Autophagy. International conference

    2020.2 

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    Event date: 2020.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • FoxO1転写因子はp21の発現および細胞周期抑制を促進し、TGFβシグナルによる軟骨分化を制御する

    倉員 市郎, 赤崎 幸穂, 林田 光正, 後藤 徳雄, 居石 卓也, 遠矢 政和, 桑原 正成, 中島 康晴

    第34回 日本整形外科学会基礎学術集会  2019.10 

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    Event date: 2019.10

    Language:Japanese  

    Country:Japan  

  • OW-HTO前後における内側laxityの変化に影響する因子の検討

    赤崎幸穂、水内秀城、濵井 敏、中島康晴

    第45回九州膝関節研究会  2019.3 

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    Event date: 2019.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • FoxO1転写因子はTGFβ1シグナルによる軟骨分化を制御する

    倉員市郎、赤崎幸穂、林田光正、後藤徳雄、居石卓也、遠矢政和、桑原正成、中島康晴

    第32回日本軟骨代謝学会  2019.2 

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    Event date: 2019.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • FoxO1 transcription factor regulates chondrogenic differentiation via TGFβ1 signaling International conference

    2019.2 

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    Event date: 2019.2

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  • JourneyⅡBCSの術中屈曲ギャップ評価に大腿骨と脛骨骨切り面の位置関係が及ぼす影響

    赤崎幸穂、水内秀城、濵井 敏、中島康晴

    第24回Fukuoka knee society  2018.10 

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • G protein-coupled receptor kinase (GRK)-5阻害は、NFκB経路の制御を介して変形性関節症における軟骨変性を抑制する

    居石卓也, 赤崎幸穂, 後藤徳雄, 倉員市郎, 遠矢政和, 桑原正成, 中島康晴

    第33回日本整形外科学会基礎学術集会  2018.9 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • サルコイドーシスに伴う難治性膝関節滑膜炎の1例

    赤崎幸穂、安元慧大朗、福士純一、池村聡、藤原稔史、中島康晴

    第56回九州リウマチ学会  2018.9 

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    Event date: 2018.9

    Language:Japanese  

    Country:Japan  

  • 高位脛骨骨切術後長期における患者立脚型評価不良例の検討

    赤崎幸穂

    第5回九州knee osteotomy 研究会  2018.7 

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    Event date: 2018.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • G protein-coupled receptor kinase (GRK)-5阻害は, NFκB経路を介した炎症反応を抑えることにより変形性関節症の軟骨変性を抑制する

    居石卓也, 赤崎幸穂, 福士純一, 池村聡, 後藤徳雄, 倉員市郎, 遠矢政和, 中島康晴

    第62回日本リウマチ学会総会・学術集会  2018.4 

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    Event date: 2018.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 樹枝状脂肪腫(lipoma arborescens)による両膝関節炎の1例

    赤崎幸穂, 福士純一, 池村 聡, 中島康晴

    第55回九州リウマチ学会  2018.3 

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    Event date: 2018.3

    Language:Japanese  

    Country:Japan  

  • 外側楔状足底板を使用した術前立位Xpによる高位脛骨骨切り術後のJLCAの予測

    赤崎幸穂、後藤徳雄、水内秀城、濱井 敏、中島康晴

    九州膝研究会  2018.3 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 外側楔状足底板を使用した術前立位Xpによる高位脛骨骨切り術後のJLCAの予測

    赤崎幸穂、後藤徳雄、水内秀城、濱井 敏、中島康晴

    第23回Fukuoka Knee Society  2017.10 

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    Event date: 2017.10 - 2017.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変性軟骨過程におけるTransthyretin性アミロイド沈着の病的意義

    赤崎幸穂, 福士純一, 池村 聡, 中島康晴

    第54回九州リウマチ学会  2017.9 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 脛骨外側プラトー骨折後の外反変形膝に対してDouble Level Osteotomyを施行した1例

    赤崎幸穂

    第4 回 九州Knee Osteotomy 研究会  2017.8 

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    Event date: 2017.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変形性関節症におけるFOXO転写因子の発現異常と機能解析

    赤崎幸穂, 岡崎 賢, 福士純一, 池村 聡, 原口 明久, 居石 卓也, 中島康晴

    第61回日本リウマチ学会総会・学術集会  2017.4 

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    Event date: 2017.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • TKAのキネマティックスと患者満足度 International conference

    赤崎幸穂, 岡崎 賢, 水内秀城, 濱井 敏

    2017.4 

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    Event date: 2017.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変形性関節症におけるtransthyretin性アミロイド沈着の病的意義

    赤崎 幸穂, Martin K. Lotz, 岡崎 賢, 岩本 幸英

    第31回日本整形外科学会基礎学術集会  2016.10 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 軟骨変性過程におけるTransthyretin性アミロイド沈着の病的意義の検討

    赤崎 幸穂, Martin K. Lotz, 岡崎 賢, 水内 秀城, 濵井 敏, 岩本 幸英

    第8回日本関節鏡・膝・スポーツ整形外科学会  2016.7 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 変形性関節症におけるTransthyretin性アミロイド沈着の病態意義の検討

    赤崎幸穂, Martin K. Lotz, 岡崎 賢, 岩本幸英

    第89回日本整形外科学会学術総会  2016.5 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 変性軟骨過程におけるTransthyretin性アミロイド沈着の病態意義の検討

    赤崎幸穂, 岡崎 賢, 岩本幸英

    第60回日本リウマチ学会総会・学術集会  2016.4 

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    Event date: 2016.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 変性軟骨におけるTransthyretin性アミロイド沈着

    赤崎幸穂, Martin K. Lotz, 岡崎 賢, 岩本幸英

    第29回日本軟骨代謝学会  2016.2 

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    Event date: 2016.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島   Country:Japan  

  • Transthyretin Deposition Accelerates the Development of Experimental Osteoarthritis in Mice. International conference

    Matsuzaki T, Alvarez-Garcia O, Akasaki Y, Reixach N, Buxbaum J, Lotz MK

    The 2015 American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) Annual Meeting  2015.11 

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    Event date: 2015.11

    Language:English  

    Country:United States  

  • 軟骨変性過程におけるForkhead box O (FOXO) 転写因子の役割

    赤崎幸穂, Martin K. Lotz, 浅原弘嗣, 岩本幸英

    第30回日本整形外科学会基礎学集会  2015.10 

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    Event date: 2015.10 - 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:富山   Country:Japan  

  • Suppression of REDD1 in OA cartilage, a novel mechanism for dysregulated mTOR activation International conference

    Alvarez-Garcia O, Akagi R, Yukio Akasaki, Fisch KM, Su AI, Lotz MK

    The 2015 Osteoarthritis Research Society International (OARSI) World Congress  2015.4 

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    Event date: 2015.4 - 2015.5

    Language:English  

    Country:United States  

  • 家兎変形性関節症モデルに対するスタチン関節内投与の効果

    赤崎 幸穂、松田 秀一、中山 功一、深川 真吾、光安 浩章、三浦 裕正、岩本 幸英

    第23回日本整形外科学会基礎学集会  2008.10 

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    Event date: 2008.10

    Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  • 家兎変形性関節症モデルに対するスタチン関節内投与の効果

    赤崎 幸穂、松田 秀一、中山 功一、深川 真吾、三浦 裕正、岩本 幸英

    第21回 日本軟骨代謝学会  2008.3 

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    Event date: 2008.3

    Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

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MISC

  • 新規NF‒κB シグナル促進因子(GRK5 とIKKε)の阻害薬(アンレキサノクス)を用いたOA 治療薬開発 Reviewed

    赤崎幸穂, 居石卓也, 内田泰輔, 廣瀬良太, 兵藤裕貴, 境真未子, 中島康晴

    整形・災害外科66:1441-1450,2023   2023.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • GRK5とIKKεのデュアル阻害薬(アンレキサノクス)を用いたOA治療薬開発 Reviewed

    赤崎幸穂, 居石卓也, 内田泰輔, 廣瀬良太, 兵藤裕貴, 境真未子, 中島康晴

    2023.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Vocabulary GRK5

    2020.12

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • スタチンの関節内投与による抗炎症効果 ~変形性関節症に対する治療薬としての可能性~

    赤崎幸穂, 松田秀一,岩本幸英

    2009.11

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Industrial property rights

Patent   Number of applications: 2   Number of registrations: 0
Utility model   Number of applications: 0   Number of registrations: 0
Design   Number of applications: 0   Number of registrations: 0
Trademark   Number of applications: 0   Number of registrations: 0

Professional Memberships

  • 日本リウマチ学会

  • 日本軟骨代謝学会

  • 西日本整形・災害外科学会

  • 日本整形外科学会

  • 日本人工関節学会

  • 日本膝関節学会

  • 九州リウマチ学会

  • 日本knee osteotomy and joint preservation 研究会

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Committee Memberships

  • Councilor   Domestic

    2023.4 - 2028.3   

  • Organizer   Domestic

    2020.10 - 2031.12   

  • Organizer   Domestic

    2020.3 - 2031.12   

Academic Activities

  • Screening of academic papers

    Role(s): Peer review

    2023

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

  • Screening of academic papers

    Role(s): Peer review

    2022

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:2

  • Screening of academic papers

    Role(s): Peer review

    2021

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:3

  • Screening of academic papers

    Role(s): Peer review

    2020

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:9

  • Screening of academic papers

    Role(s): Peer review

    2019

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:8

  • Screening of academic papers

    Role(s): Peer review

    2018

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:10

  • Screening of academic papers

    Role(s): Peer review

    2017

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:5

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Research Projects

  • アンレキサノクスとヒアルロン酸を原薬とした変形性関節症(OA)治療薬の開発

    2022.9 - 2033.6

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    Authorship:Principal investigator 

    本研究課題の最終目標は、アンレキサノクスとヒアルロン酸を原薬としたOA疾患修飾効果を発揮する新規関節内投与治療薬を開発し、実用化することである。九州大学整形外科において、アンレキサノクスの薬効機序(GRK5およびIKKεの機能阻害による軟骨変性抑制・OA病態修飾作用)を解明し、溶媒添加により関節腔内注射に適した剤形を決定した。臨床用法用量も設定できている。アンレキサノクスとヒアルロン酸の相乗効果に関する特許のPCT出願も完了した。
    製薬会社と共同研究契約を締結しており、品質規格設定、非臨床安全性試験内容の設定に関するPMDA対面助言を行う。その後に、日本医療研究開発機構の橋渡し研究プログラムなどにグラント申請して、非臨床GLP試験を実施し、第Ⅰ/Ⅱ相治験実施を目指す。

  • 日本整形外科学会プロジェクト研究事業:久山町研究におけるロコモ・フレイルコホートの設立

    2022.4 - 2025.3

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    Authorship:Principal investigator 

  • 実臨床に即した変形性関節症の病期特異的治療ターゲットの探索

    2022 - 2024

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 実臨床に即した変形性関節症の病期特異的治療ターゲットの探索

    Grant number:22K09306  2022 - 2024

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 久山町研究におけるロコモ・フレイルコホートの設立

    2022 - 2024

    日本整形外科学会プロジェクト研究事業

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    Authorship:Principal investigator  Grant type:Contract research

  • IKKε阻害による変形性関節症に対する関節内投与治療薬の開発

    2021 - 2022

    令和3 年度 橋渡し研究・新規開発シーズ(シーズA 九州大学公募)

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    Authorship:Principal investigator  Grant type:Contract research

  • 変形性関節症に対する新規関節内投与治療薬の開発

    2020 - 2021

    橋渡し研究戦略的推進プログラム

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    Authorship:Principal investigator  Grant type:Contract research

  • 高密度スキャフォールドフリー脂肪由来幹細胞構造体を用いた骨軟骨組織再生の実用化推進臨床研究

    2017.7 - 2020.3

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    Authorship:Coinvestigator(s) 

  • 変形性関節症の早期病態に即した治療標的分子の探索

    Grant number:17H05097  2017 - 2021

    科学研究費助成事業  若手研究(A)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 高密度スキャフォールドフリー脂肪由来幹細胞構造体を用いた骨軟骨組織再生の実用化推進臨床研究

    2017 - 2019

    AMED再生医療実用化研究事業(01)

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    Authorship:Coinvestigator(s)  Grant type:Contract research

  • 変形性関節症の早期病態に即した治療標的分子の探索

    2017 - 2018

    武田科学振興財団 「2017年度 医学系研究奨励」

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    Authorship:Principal investigator  Grant type:Contract research

  • FOXOターゲット因子、C10orf10/DEPP蛋白の軟骨細胞における機能解析と軟骨変性治療標的としての有用性の検討

    2017

    第34回整形災害外科学研究助成財団

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    Authorship:Principal investigator  Grant type:Contract research

  • 長寿遺伝子であるFOXO転写因子の活性化による変形性関節症治療

    2016 - 2017

    平成28年度長寿科学研究者支援事業

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    Authorship:Principal investigator  Grant type:Contract research

  • 間葉系幹細胞移植と併用したスタチン製剤の関節内投与による軟骨再生促進の試み

    2016

    中冨健康科学振興財団研究助成金

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    Authorship:Principal investigator  Grant type:Contract research

  • 変形性関節症における新しい病態機序-Transthyretin性アミロイド沈着-

    2015 - 2016

    日本学術振興会  科学研究費助成事業  研究活動スタート支援

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 軟骨変性と軟骨再生過程における低分子量G蛋白と細胞骨格・接着因子の関与の解明

    2012 - 2013

    日本学術振興会  海外特別研究員

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    Authorship:Principal investigator  Grant type:Joint research

  • 変形性関節症に対する新規治療薬の開発-既存の高脂血症薬(スタチン)を用いて-

    2007

    九州大学21COE プログラム若手研究者研究費

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    Authorship:Principal investigator  Grant type:On-campus funds, funds, etc.

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Class subject

  • 保健学科臨床医学論Ⅱ_コンタクトスポーツ外傷

    2023.10 - 2024.3   Second semester

  • 脊椎運動器:コンタクトスポーツの医学

    2023.4 - 2023.9   First semester

  • 脊椎運動器:膝関節の外傷

    2023.4 - 2023.9   First semester

  • 病態制御学1ー①関節疾患

    2023.4 - 2023.9   First semester

  • 保健学科臨床医学論Ⅱ_コンタクトスポーツ外傷

    2022.10 - 2023.3   Second semester

  • 病態制御学1ー①関節疾患

    2022.4 - 2022.9   First semester

  • 脊椎運動器:膝関節の外傷

    2022.4 - 2022.9   First semester

  • 脊椎運動器:コンタクトスポーツの医学

    2022.4 - 2022.9   First semester

  • スポーツ医学_スポーツ外傷ににおける下肢外傷・障害

    2021.10 - 2022.3   Second semester

  • スポーツ医学_コンタクトスポーツ

    2021.10 - 2022.3   Second semester

  • 保健学科臨床医学論Ⅱ_コンタクトスポーツ外傷

    2021.10 - 2022.3   Second semester

  • 病態制御学1ー①関節疾患

    2021.4 - 2021.9   First semester

  • 脊椎運動器:膝関節の外傷

    2021.4 - 2021.9   First semester

  • 保健学科臨床医学論Ⅱ_コンタクトスポーツ外傷

    2020.10 - 2021.3   Second semester

  • スポーツ医学_コンタクトスポーツ

    2020.10 - 2021.3   Second semester

  • スポーツ医学_スポーツ外傷ににおける下肢外傷・障害

    2020.10 - 2021.3   Second semester

  • 脊椎運動器:膝関節の外傷

    2020.4 - 2020.9   First semester

  • 病態制御学1ー①関節疾患

    2020.4 - 2020.9   First semester

  • 保健学科臨床医学論Ⅱ_コンタクトスポーツ外傷

    2019.10 - 2020.3   Second semester

  • スポーツ医学_コンタクトスポーツ

    2019.10 - 2020.3   Second semester

  • 脊椎運動器:膝関節の外傷

    2019.4 - 2019.9   First semester

  • 病態制御学1ー①関節疾患

    2019.4 - 2019.9   First semester

  • 脊椎運動器:膝関節の外傷

    2018.4 - 2018.9   First semester

  • 総合医学Ⅶ「医療イノベーション科目Ⅰ」軟骨再生治療の現状と展望

    2017.10 - 2018.3   Second semester

  • 脊椎運動器:膝関節の外傷

    2017.4 - 2017.9   First semester

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Outline of Social Contribution and International Cooperation activities

  • 国際診療支援センターを通じた海外からの整形外科患者受け入れの窓口担当

Travel Abroad

  • 2012.4 - 2015.2

    Staying countory name 1:United States   Staying institution name 1:The Scripps Research Institute

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Surgical Clinical Medicine / Orthopedic Surgery

Clinician qualification

  • Specialist

    The Japanese Orthopaedic Association(JOA)

  • Specialist

    Japan College of Rheumatology(JCR)

Year of medical license acquisition

  • 2002

Notable Clinical Activities

  • 人工膝関節置換術、膝周囲骨切り術