Updated on 2025/06/30

Information

 

写真a

 
HIRANO SHOGO
 
Organization
Kyushu University Hospital Neuro-Psychiatry Lecturer
School of Medicine Department of Medicine（Concurrent）
Title
Lecturer
Profile
neurophysiological research of psychiaric patients
External link

Degree

  • PhD

Research History

  • Kyushu University 精神科神経科 Lecturer 

    2025.4

  • 2000年5月~2002年5月　九州大学医学部附属病院　精神科神経科　研修医 2002年5月~2004年5月　国立小倉病院　精神神経科　レジデント 2004年5月~2005年3月　九州大学病院　精神科神経科　医員 2009年5月~2010年9月　九州大学大学院医学研究院　精神病態医学　特別教員 2010年10月~2011年3月　九州大学病院　リハビリテーション部　助教 2011年4月~2014年3月　医療法人豊永会　飯塚記念病院　精神科医師 2014年4月~2017年3月 Post doctoral research fellow, Research Service, Veterans Affairs Boston Healthcare System; and Department of Psychiatry, Harvard Medical School, Boston, U.S.A. 2017年4月~　九州大学病院　精神科神経科　助教   

    2000年5月~2002年5月　九州大学医学部附属病院　精神科神経科　研修医 2002年5月~2004年5月　国立小倉病院　精神神経科　レジデント 2004年5月~2005年3月　九州大学病院　精神科神経科　医員 2009年5月~2010年9月　九州大学大学院医学研究院　精神病態医学　特別教員 2010年10月~2011年3月　九州大学病院　リハビリテーション部　助教 2011年4月~2014年3月　医療法人豊永会　飯塚記念病院　精神科医師 2014年4月~2017年3月 Post doctoral research fellow, Research Service, Veterans Affairs Boston Healthcare System; and Department of Psychiatry, Harvard Medical School, Boston, U.S.A. 2017年4月~　九州大学病院　精神科神経科　助教

Research Interests・Research Keywords

  • Research theme： Neurophysiological research on psychiatric patients

    Keyword： schizophrenia, bipolar disorder, magnetoencephalography, electroencephalography

    Research period： 2005.4 - 2011.3

Awards

  • 第105回日本精神神経学会精神医学奨励賞

    2009.8   日本精神神経学会   Abnormal neural oscillatory activity to speech sounds in schizophrenia: a MEG study.

Papers

  • Phase-Amplitude Coupling of the Electroencephalogram in the Auditory Cortex in Schizophrenia. Invited Reviewed International journal

    @Shogo Hirano, Alexander Nakhnikian, @Yoji Hirano, @Naoya Oribe, @Shigenobu Kanba, @Toshiaki Onitsuka, Margaret Levin, Kevin M. Spencer

    Biological Psychiatry: Cognitive Neuroscience and Neuroimaging   3 ( 1 )   69 - 76   2018.1

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： doi:10.1016/j.bpsc.2017.09.001

  • Abnormal neural oscillatory activity to speech sounds in schizophrenia: a MEG study. Reviewed International journal

    Hirano S, Hirano Y, Maekawa T, Obayashi C, Oribe N, Kuroki T, Kanba S, Onitsuka T

    Journal of Neuroscience   28 ( 19 )   2008.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1523/JNEUROSCI.5031-07.2008

  • Successful Management of ECT-Resistant Interictal Psychosis With Clozapine A Case Report

    Mitoma, R; Hirano, S; Nakao, T

    JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY   44 ( 5 )   527 - 528   2024.9   （ ISSN:0271-0749 eISSN:1533-712X ）

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    Language：English   Publisher：Journal of Clinical Psychopharmacology  

    DOI： 10.1097/JCP.0000000000001904

    Web of Science

    Scopus

    PubMed

  • Aberrant thalamocortical connectivity and shifts between the resting state and task state in patients with schizophrenia

    Takai, Y; Tamura, S; Hoaki, N; Kitajima, K; Nakamura, I; Hirano, S; Ueno, T; Nakao, T; Onitsuka, T; Hirano, Y

    EUROPEAN JOURNAL OF NEUROSCIENCE   59 ( 8 )   1961 - 1976   2024.4   （ ISSN:0953-816X eISSN:1460-9568 ）

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    Language：English   Publisher：European Journal of Neuroscience  

    Prominent pathological hypotheses for schizophrenia include auditory processing deficits and dysconnectivity within cerebral networks. However, most neuroimaging studies have focused on impairments in either resting-state or task-related functional connectivity in patients with schizophrenia. The aims of our study were to examine (1) blood oxygen level-dependent (BOLD) signals during auditory steady-state response (ASSR) tasks, (2) functional connectivity during the resting-state and ASSR tasks and (3) state shifts between the resting-state and ASSR tasks in patients with schizophrenia. To reduce the functional consequences of scanner noise, we employed resting-state and sparse sampling auditory fMRI paradigms in 25 schizophrenia patients and 25 healthy controls. Auditory stimuli were binaural click trains at frequencies of 20, 30, 40 and 80 Hz. Based on the detected ASSR-evoked BOLD signals, we examined the functional connectivity between the thalamus and bilateral auditory cortex during both the resting state and ASSR task state, as well as their alterations. The schizophrenia group exhibited significantly diminished BOLD signals in the bilateral auditory cortex and thalamus during the 80 Hz ASSR task (corrected p < 0.05). We observed a significant inverse relationship between the resting state and ASSR task state in altered functional connectivity within the thalamo-auditory network in schizophrenia patients. Specifically, our findings demonstrated stronger functional connectivity in the resting state (p < 0.004) and reduced functional connectivity during the ASSR task (p = 0.048), which was mediated by abnormal state shifts, within the schizophrenia group. These results highlight the presence of abnormal thalamocortical connectivity associated with deficits in the shift between resting and task states in patients with schizophrenia.

    DOI： 10.1111/ejn.16298

    Web of Science

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  • Spectral decomposition of resting state electroencephalogram reveals unique theta/alpha activity in schizophrenia

    Nakhnikian, A; Oribe, N; Hirano, S; Fujishima, Y; Hirano, Y; Nestor, PG; Francis, GA; Levin, M; Spencer, KM

    EUROPEAN JOURNAL OF NEUROSCIENCE   59 ( 8 )   1946 - 1960   2024.4   （ ISSN:0953-816X eISSN:1460-9568 ）

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    Language：English   Publisher：European Journal of Neuroscience  

    Resting state electroencephalographic (EEG) activity in schizophrenia (SZ) is frequently characterised by increased power at slow frequencies and/or a reduction of peak alpha frequency. Here we investigated the nature of these effects. As most studies to date have been limited by reliance on a priori frequency bands which impose an assumed structure on the data, we performed a data-driven analysis of resting EEG recorded in SZ patients and healthy controls (HC). The sample consisted of 39 chronic SZ and 36 matched HC. The EEG was recorded with a dense electrode array. Power spectral densities were decomposed via Varimax-rotated principal component analysis (PCA) over all participants and for each group separately. Spectral PCA was repeated at the cortical level on cortical current source density computed from standardised low resolution brain electromagnetic tomography. There was a trend for power in the theta/alpha range to be increased in SZ compared to HC, and peak alpha frequency was significantly reduced in SZ. PCA revealed that this frequency shift was because of the presence of a spectral component in the theta/alpha range (6–9 Hz) that was unique to SZ. The source distribution of the SZ > HC theta/alpha effect involved mainly prefrontal and parahippocampal areas. Abnormal low frequency resting EEG activity in SZ was accounted for by a unique theta/alpha oscillation. Other reports have described a similar phenomenon suggesting that the neural circuits oscillating in this range are relevant to SZ pathophysiology.

    DOI： 10.1111/ejn.16244

    Web of Science

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  • Abnormal phase entrainment of low- and high-gamma-band auditory steady-state responses in schizophrenia

    Nakanishi, S; Tamura, S; Hirano, S; Takahashi, J; Kitajima, K; Takai, Y; Mitsudo, T; Togao, O; Nakao, T; Onitsuka, T; Hirano, Y

    FRONTIERS IN NEUROSCIENCE   17   1277733   2023.10   （ ISSN:16624548 eISSN:1662-453X ）

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    Language：English   Publisher：Frontiers in Neuroscience  

    Introduction: Gamma-band oscillatory deficits have attracted considerable attention as promising biomarkers of schizophrenia (SZ). Notably, a reduced auditory steady-state response (ASSR) in the low gamma band (40 Hz) is widely recognized as a robust finding among SZ patients. However, a comprehensive investigation into the potential utility of the high-gamma-band ASSR in detecting altered neural oscillations in SZ has not yet been conducted. Methods: The present study aimed to assess the ASSR using magnetoencephalography (MEG) data obtained during steady-state stimuli at frequencies of 20, 30, 40, and 80 Hz from 23 SZ patients and 21 healthy controls (HCs). To evaluate the ASSR, we examined the evoked power and phase-locking factor (PLF) in the time-frequency domain for both the primary and secondary auditory cortices. Furthermore, we calculated the phase-locking angle (PLA) to examine oscillatory phase lead or delay in SZ patients. Taking advantage of the high spatial resolution of MEG, we also focused on the hemispheric laterality of low- and high-gamma-band ASSR deficits in SZ. Results: We found abnormal phase delay in the 40 Hz ASSR within the bilateral auditory cortex of SZ patients. Regarding the 80 Hz ASSR, our investigation identified an aberrant phase lead in the left secondary auditory cortex in SZ, accompanied by reduced evoked power in both auditory cortices. Discussion: Given that abnormal phase lead on 80 Hz ASSR exhibited the highest discriminative power between HC and SZ, we propose that the examination of PLA in the 80 Hz ASSR holds significant promise as a robust candidate for identifying neurophysiological endophenotypes associated with SZ. Furthermore, the left-hemisphere phase lead observed in the deficits of 80 Hz PLA aligns with numerous prior studies, which have consistently proposed that SZ is characterized by left-lateralized brain dysfunctions.

    DOI： 10.3389/fnins.2023.1277733

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  • 治療抵抗性および超治療抵抗性統合失調症患者における左内側頭頂葉の脳回低形成と表面積減少(Decreased cortical gyrification and surface area in the left medial parietal cortex in patients with treatment-resistant and ultratreatment-resistant schizophrenia)

    Kitajima Kazutoshi, Tamura Shunsuke, Sasabayashi Daiki, Nakajima Shinichiro, Iwata Yusuke, Ueno Fumihiko, Takai Yoshifumi, Takahashi Junichi, Caravaggio Fernando, Mar Wanna, Torres-Carmona Edgardo, Noda Yoshihiro, Gerretsen Philip, de Luca Vincenzo, Mimura Masaru, Hirano Shogo, Nakao Tomohiro, Onitsuka Toshiaki, Remington Gary, Graff-Guerrero Ariel, Hirano Yoji

    Psychiatry and Clinical Neurosciences   77 ( 1-2 )   2 - 11   2023.2   （ ISSN:1323-1316 ）

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    Language：English   Publisher：John Wiley & Sons Australia, Ltd  

    治療抵抗性統合失調症(TRS)に特異的な脳回形成異常と表面積異常を明らかにした。健常対照(HC)24名(平均41.5±13.5歳)、ファーストライン抗精神病薬(FL)に反応した患者(FL-Resp)20名(平均43.8±12.6歳)、クロザピンに反応したTRS患者(CLZ-Resp)19名(平均43.1±13.8歳)、FLおよびクロザピン抵抗性のTRS患者(URS)22名(平均45.9±11.9歳)を対象に、3T MRI画像の解析を行った。局所脳回指数(LGI)および関連する表面積を群間で解析・比較した。その結果、CLZ-RespとURSはともに左内側頭頂葉(Lt-MPC)においてHCおよびFL-Respより低いLGIであった。CLZ-RespとURSはともにFL-RespよりもLt-MPCの表面積が狭かった。LGIと表面積は非TRS(Fl-Resp)およびTRS(CLZ-Resp+URS)で正の相関を示した。Lt-MPCにおけるLGIと表面積を用いた非TRSとTRSのROC曲線下面積はそれぞれ0.79と0.85であった。Lt-MPCの表面積はTRSの陰性症状およびクロザピン血中濃度と逆相関していた。以上から、Lt-MPCのLGIと表面積の変化は、TRSの遺伝的脆弱性に関連する構造的特徴であると考えられた。

  • Decreased cortical gyrification and surface area in the left medial parietal cortex in patients with treatment-resistant and ultratreatment-resistant schizophrenia

    Kitajima, K; Tamura, S; Sasabayashi, D; Nakajima, S; Iwata, Y; Ueno, F; Takai, Y; Takahashi, J; Caravaggio, F; Mar, W; Torres-Carmona, E; Noda, Y; Gerretsen, P; de Luca, V; Mimura, M; Hirano, S; Nakao, T; Onitsuka, T; Remington, G; Graff-Guerrero, A; Hirano, Y

    PSYCHIATRY AND CLINICAL NEUROSCIENCES   77 ( 1 )   2 - 11   2023.1   （ ISSN:1323-1316 eISSN:1440-1819 ）

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    Language：English   Publisher：Psychiatry and Clinical Neurosciences  

    Aim: Validating the vulnerabilities and pathologies underlying treatment-resistant schizophrenia (TRS) is an important challenge in optimizing treatment. Gyrification and surface area (SA), reflecting neurodevelopmental features, have been linked to genetic vulnerability to schizophrenia. The aim of this study was to identify gyrification and SA abnormalities specific to TRS. Methods: We analyzed 3T magnetic resonance imaging findings of 24 healthy controls (HCs), 20 responders to first-line antipsychotics (FL-Resp), and 41 patients with TRS, including 19 clozapine responders (CLZ-Resp) and 22 FL- and clozapine-resistant patients (patients with ultratreatment-resistant schizophrenia [URS]). The local gyrification index (LGI) and associated SA were analyzed across groups. Diagnostic accuracy was verified by receiver operating characteristic curve analysis. Results: Both CLZ-Resp and URS had lower LGI values than HCs (P = 0.041, Hedges g [g<inf>H</inf>] = 0.75; P = 0.013, g<inf>H</inf> = 0.96) and FL-Resp (P = 0.007, g<inf>H</inf> = 1.00; P = 0.002, g<inf>H</inf> = 1.31) in the left medial parietal cortex (Lt-MPC). In addition, both CLZ-Resp and URS had lower SA in the Lt-MPC than FL-Resp (P < 0.001, g<inf>H</inf> = 1.22; P < 0.001, g<inf>H</inf> = 1.75). LGI and SA were positively correlated in non-TRS (FL-Resp) (ρ = 0.64, P = 0.008) and TRS (CLZ-Resp + URS) (ρ = 0.60, P < 0.001). The areas under the receiver operating characteristic curve for non-TRS versus TRS with LGI and SA in the Lt-MPC were 0.79 and 0.85, respectively. SA in the Lt-MPC was inversely correlated with negative symptoms (ρ = −0.40, P = 0.018) and clozapine plasma levels (ρ = −0.35, P = 0.042) in TRS. Conclusion: LGI and SA in the Lt-MPC, a functional hub in the default-mode network, were abnormally reduced in TRS compared with non-TRS. Thus, altered LGI and SA in the Lt-MPC might be structural features associated with genetic vulnerability to TRS.

    DOI： 10.1111/pcn.13482

    Web of Science

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  • Lower Hippocampal Volume in Patients with Schizophrenia and Bipolar Disorder: A Quantitative MRI Study Reviewed International journal

    Sato, Jinya; Hirano, Yoji; Hirakawa, Noriaki; Takahashi, Junichi; Oribe, Naoya; Kuga, Hironori; Nakamura, Itta; Hirano, Shogo; Ueno, Takefumi; Togao, Osamu; Hiwatashi, Akio; Nakao, Tomohiro; Onitsuka, Toshiaki

    JOURNAL OF PERSONALIZED MEDICINE   11 ( 2 )   2021.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3390/jpm11020121

  • Neuroanatomical substrate of chronic psychosis in epilepsy: an MRI study Reviewed International journal

    Hirakawa, Noriaki; Kuga, Hironori; Hirano, Yoji; Sato, Jinya; Oribe, Naoya; Nakamura, Itta; Hirano, Shogo; Ueno, Takefumi; Oda, Yuko; Togao, Osamu; Hiwatashi, Akio; Honda, Hiroshi; Kanba, Shigenobu; Onitsuka, Toshiaki

    BRAIN IMAGING AND BEHAVIOR   14 ( 5 )   1382 - 1387   2020.10

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s11682-019-00044-4

  • Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia: An MEG Study Invited Reviewed International journal

    Ohara, Naotoshi; Hirano, Yoji; Oribe, Naoya; Tamura, Shunsuke; Nakamura, Itta; Hirano, Shogo; Tsuchimoto, Rikako; Ueno, Takefumi; Togao, Osamu; Hiwatashi, Akio; Nakao, Tomohiro; Onitsuka, Toshiaki

    FRONTIERS IN PSYCHIATRY   11   2020.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.3389/fpsyt.2020.554844

  • Right hemisphere pitch-mismatch negativity reduction in patients with major depression: An MEG study Reviewed International journal

    Hirakawa, Noriaki; Hirano, Yoji; Nakamura, Itta; Hirano, Shogo; Sato, Jinya; Oribe, Naoya; Ueno, Takefumi; Kanba, Shigenobu; Onitsuka, Toshiaki

    JOURNAL OF AFFECTIVE DISORDERS   215   225 - 229   2017.6

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jad.2017.03.046

  • Differentiation between major depressive disorder and bipolar disorder by auditory steady-state responses Reviewed International journal

    Isomura, Shuichi; Onitsuka, Toshiaki; Tsuchimoto, Rikako; Nakamura, Itta; Hirano, Shogo; Oda, Yuko; Oribe, Naoya; Hirano, Yoji; Ueno, Takefumi; Kanba, Shigenobu

    JOURNAL OF AFFECTIVE DISORDERS   190   800 - 806   2016.1

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jad.2015.11.034

  • Early Integration Processing between Faces and Vowel Sounds in Human Brain: An MEG Investigation Reviewed International journal

    Nakamura, Itta; Hirano, Yoji; Ohara, Naotoshi; Hirano, Shogo; Ueno, Takefumi; Tsuchimoto, Rikako; Kanba, Shigenobu; Onitsuka, Toshiaki

    NEUROPSYCHOBIOLOGY   71 ( 4 )   187 - 195   2015.6

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1159/000377680

  • Preattentive dysfunction in patients with bipolar disorder as revealed by the pitch-mismatch negativity: a magnetoencephalography (MEG) study Reviewed International journal

    Shimano, Satomi; Onitsuka, Toshiaki; Oribe, Naoya; Maekawa, Toshihiko; Tsuchimoto, Rikako; Hirano, Shogo; Ueno, Takefumi; Hirano, Yoji; Miura, Tomofumi; Kanba, Shigenobu

    BIPOLAR DISORDERS   16 ( 6 )   592 - 599   2014.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/bdi.12208

  • Altered face inversion effect and association between face N170 reduction and social dysfunction in patients with schizophrenia Reviewed International journal

    Tsunoda, Tomoya; Kanba, Shigenobu; Ueno, Takefumi; Hirano, Yoji; Hirano, Shogo; Maekawa, Toshihiko; Onitsuka, Toshiaki

    CLINICAL NEUROPHYSIOLOGY   123 ( 9 )   1762 - 1768   2012.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.clinph.2012.01.024

  • Gamma Band Neural Synchronization Deficits for Auditory Steady State Responses in Bipolar Disorder Patients Reviewed International journal

    Oda, Yuko; Onitsuka, Toshiaki; Tsuchimoto, Rikako; Hirano, Shogo; Oribe, Naoya; Ueno, Takefumi; Hirano, Yoji; Nakamura, Itta; Miura, Tomofumi; Kanba, Shigenobu

    PLOS ONE   7 ( 7 )   2012.7

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1371/journal.pone.0039955

  • Reduced high and low frequency gamma synchronization in patients with chronic schizophrenia Reviewed International journal

    Tsuchimoto, Rikako; Kanba, Shigenobu; Hirano, Shogo; Oribe, Naoya; Ueno, Takefumi; Hirano, Yoji; Nakamura, Itta; Oda, Yuko; Miura, Tomofumi; Onitsuka, Toshiaki

    SCHIZOPHRENIA RESEARCH   133 ( 1-3 )   99 - 105   2011.12

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.schres.2011.07.020

  • Stability of the Rayleigh distribution. Reviewed International journal

    Ueno T, Hirano S, Hirano Y, Oribe N, Nakamura I, Oda Y, Kanba S, Onitsuka T

    CISP 2011 4th International Congress on 5   2376 - 2378   2011.10

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Differentiation between bipolar disorder and schizophrenia revealed by neural oscillation to speech sounds: an MEG study. Reviewed International journal

    Oribe, Naoya; Onitsuka, Toshiaki; Hirano, Shogo; Hirano, Yoji; Maekawa, Toshihiko; Obayashi, Choji; Ueno, Takefumi; Kasai, Kiyoto; Kanba, Shigenobu

    Bipolar Disorders   12 ( 8 )   2010.12

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Auditory gating deficit to human voices in schizophrenia: A MEG study. Reviewed International journal

    Hirano, Yoji; Hirano, Shogo; Maekawa, Toshihiko; Obayashi, Choji; Oribe, Naoya; Monji, Akira; Kasai, Kiyoto; Kanba, Shigenobu; Onitsuka, Toshiaki

    Schizophrenia Research   117 ( 1 )   2010.3

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  • Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia Reviewed International journal

    Obayashi, Choji; Nakashima, Taisuke; Onitsuka, Toshiaki; Maekawa, Toshihiko; Hirano, Yoji; Hirano, Shogo; Oribe, Naoya; Kaneko, Kunihiko; Kanba, Shigenobu; Tobimatsu, Shozo

    CLINICAL NEUROPHYSIOLOGY   120 ( 8 )   1525 - 1533   2009.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.clinph.2009.06.016

  • Locked to stimulation: significance level of the phase-locking factor. Reviewed International journal

    Ueno, Takefumi; Hirano, Shogo; Hirano, Yoji; Kanba, Shigenobu; Kobayashi, Shinji; Onitsuka, Toshiaki

    Conf Proc Imaging Signal Processing IEEE.   2009.8

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Auditory sensory gating to the human voice: A preliminary MEG study Reviewed International journal

    Hirano, Yoji; Onitsuka, Toshiaki; Kuroki, Toshihide; Matsuki, Yuji; Hirano, Shogo; Maekawa, Toshihiko; Kanba, Shigenobu

    PSYCHIATRY RESEARCH-NEUROIMAGING   163 ( 3 )   260 - 269   2008.8

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.pscychresns.2007.07.002

  • Attitude of patients with mood disorder toward clinical trials in Japan. Reviewed International journal

    Hirano S, Onitsuka T, Kuroki T, Yokota K, Higuchi T, Watanabe K, Nakamura J, Kanba S

    Journal of Clinical Psychopharmacology   27   2007.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/jcp.0b013e31802e98af

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Books

  • 神経生理学と精神医学：脳波, 誘発電位, そしてγ振動と, 精神疾患の原因に迫りつつある生理学の現状.　加藤 忠史(責任編集) : 精神医学の科学的基盤／POWERMOOK 精神医学の基盤4.

    平野 昭吾, 平河 則明, 平野 羊嗣, 鬼塚 俊明（Role：Joint author）

    学樹書院  2020.1 

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    Language：Japanese   Book type：Scholarly book

  • Schizophrenia. In: Tobimatsu S, Kakigi R(eds): Clinical applications of magnetoencephalography.

    Onitsuka T, Hirano S（Role：Joint author）

    Springer Japan  2016.2 

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    Language：English   Book type：Scholarly book

  • 視床−大脳皮質系と脳波生成. 脳科学エッセンシャル−精神疾患の生物学的理解のために. 専門医のための精神科臨床リュミエール16

    平野昭吾（Role：Joint author）

    中山書店  2010.7 

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    Responsible for pages：pp. 54-55   Language：Japanese   Book type：Scholarly book

Presentations

  • 統合失調症患者の聴覚皮質における位相振幅カップリング-脳波研究- Invited

    平野昭吾

    第41回日本生物学的精神医学会  2019.6 

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    Event date： 2019.6

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：朱鷺メッセ, 新潟市   Country：Japan  

  • Phase-amplitude coupling of the electroencephalogram in the auditory cortex in schizophrenia. International conference

    Shogo Hirano, @Alexander Nakhnikian, Yoji Hirano, Naoya Oribe, Shigenobu Kanba, Toshiaki Onitsuka, @Margaret Levin, @Kevin M. Spencer

    14th World Congress of Biological Psychiatry  2019.6 

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    Event date： 2019.6

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Vancouver Convention Centre, Vancouver   Country：Canada  

  • 統合失調症における聴覚ニューラルオシレーション研究 Invited

    平野昭吾

    第14回日本統合失調症学会  2019.4 

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    Event date： 2019.4 - 2020.4

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：北海道大学学術交流会館, 札幌市   Country：Japan  

  • Neural oscillation in phonetic discrimination: a MEG study. International conference

    平野昭吾、中村一太、上野雄文、鬼塚俊明、神庭重信

    Neuroscience 2010  2010.11 

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    Event date： 2010.11

    Presentation type：Oral presentation (general)  

    Venue：San Diego   Country：United States  

  • Auditory steady state response in patients with bipolar disorder: a magnetoencephalography study. International conference

    平野昭吾、織部直弥、土本利架子、大林長二、平野羊嗣、福嶋倫子、前川敏彦、上野雄文、鬼塚俊明、神庭重信

    Annual meeting of OHBM  2009.6 

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    Event date： 2009.6

    Presentation type：Oral presentation (general)  

    Venue：San Francisco   Country：United States  

  • 統合失調症におけるneural oscillation研究. Invited

    平野昭吾

    第31回日本生物学的精神医学会  2009.4 

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    Event date： 2009.4

    Presentation type：Symposium, workshop panel (public)  

    Venue：京都府   Country：Japan  

  • Abnormal neural oscillatory activity to speech sounds in schizophrenia: an MEG study. International conference

    平野昭吾、平野羊嗣、前川敏彦、大林長二、織部直弥、黒木俊秀、神庭重信、鬼塚俊明

    First conference of international society for the advancement of clinical magnetoencephalography  2007.8 

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    Event date： 2007.8

    Presentation type：Oral presentation (general)  

    Venue：松島   Country：Japan  

  • 言語音および非言語音に対する統合失調症者の脳磁図誘発γ帯域反応についての検討.

    平野昭吾

    第29回日本生物学的精神医学会  2007.7 

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    Event date： 2007.7

    Presentation type：Oral presentation (general)  

    Venue：札幌市   Country：Japan  

  • 頭部外傷後発症の精神病症状を伴う双極性障害にカルバマゼピンが奏功した1例

    丸山 大輝, 中澤 太郎, 豊見山 泰史, 平野 昭吾, 中尾 智博

    九州神経精神医学  2024.4  九州精神神経学会

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    Language：Japanese  

  • 非薬物療法としてメタ認知トレーニングが有効であった妄想性障害の一例

    立川 夏帆, 畑部 暢三, 高井 善史, 平野 羊嗣, 平野 昭吾, 加藤 隆弘, 中尾 智博

    九州神経精神医学  2024.8  九州精神神経学会

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    Language：Japanese  

  • 若年性ミオクロニーてんかんにおける聴性,および体性感覚性定常状態反応の異常

    三笘 良, 田村 俊介, 光藤 貴子, 成 儒彬, 重藤 寛史, 平野 羊嗣, 平野 昭吾, 中尾 智博

    てんかん研究  2023.9  (一社)日本てんかん学会

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    Language：Japanese  

  • 統合失調症者におけるメタ記憶障害に関するfMRI研究　症例研究による予備的検討

    甲斐 直路, 田村 俊介, 高井 善史, 榎本 美奈, 光藤 崇子, 平野 昭吾, 宮田 淳, 帆秋 伸彦, 平野 羊嗣, 中尾 智博

    九州神経精神医学  2024.4  九州精神神経学会

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    Language：Japanese  

  • 発作間欠期てんかん性精神病における聴性定常反応

    藤野 勝, 成 儒彬, 三笘 良, 高井 善史, 平野 昭吾, 中尾 智博

    てんかん研究  2024.9  (一社)日本てんかん学会

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    Language：Japanese  

  • 発作性運動誘発性ジスキネジアにおける体性感覚定常反応課題時の皮質活動異常

    三笘 良, 田村 俊介, 成 儒彬, 眞崎 勝久, 平野 昭吾, 中尾 智博

    精神神経学雑誌  2023.6  (公社)日本精神神経学会

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    Language：Japanese  

  • 心因性非てんかん性発作に対するBrexpiprazoleの有用性

    三笘 良, 平野 昭吾, 中尾 智博

    てんかん研究  2024.9  (一社)日本てんかん学会

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    Language：Japanese  

  • 多施設臨床脳波データのSuStaln解析による統合失調症者の層別化

    田村 俊介, 中島 振一郎, 品川 俊一郎, 成 儒彬, 中西 翔一郎, 三笘 良, 高井 善史, 平野 昭吾, 尾久 守侑, 黒瀬 心, 船橋 英樹, 藤元 貴子, 鶴田 健二, 中尾 周平, 高木 俊輔, 越山 太輔, 小池 進介, 織部 直弥, 光藤 崇子, 樋口 悠子, 朴 秀賢, 新井 脩泰, 元村 英史, 鬼塚 俊明, 石田 康, 平野 羊嗣

    精神神経学雑誌  2024.6  (公社)日本精神神経学会

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    Language：Japanese  

  • パーキンソン病に伴う器質性妄想性障害に対して,抗パーキンソン病薬を増量し奏効した一例

    矢野 智子, 平野 昭吾, 中尾 智博

    九州神経精神医学  2023.8  九州精神神経学会

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    Language：Japanese  

  • てんかん患者に合併した精神病症状

    山田 亮, 三笘 良, 平野 昭吾, 平野 羊嗣, 中尾 智博

    九州神経精神医学  2023.8  九州精神神経学会

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    Language：Japanese  

  • てんかん外科術後にde novo精神病を呈した3症例

    三苫 良, 下川 能史, 迎 伸孝, 酒井 康成, 重藤 寛史, 酒田 あゆみ, 渡邊 恵利子, 平野 昭吾, 平野 羊嗣

    てんかん研究  2022.8  (一社)日本てんかん学会

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    Language：Japanese  

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MISC

  • Language-Related Neurophysiological Deficits in Schizophrenia. Reviewed

    Shogo Hirano, @Kevin M. Spencer, Toshiaki Onitsuka, Yoji Hirano

    Clinical EEG and Neuroscience   2020.7

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    Language：English   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

    DOI： 10.1016/j.jad.2015.11.034.

  • 統合失調症のMEG研究.

    平野昭吾、鬼塚俊明、神庭重信

    精神科   2006.9

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

Professional Memberships

  • The Japanese society of psychiatry and neurology

  • The Kyushu association of neuropsychiatry

  • Japanese Society of Clinical Neurophysiology

Committee Memberships

  • 日本臨床神経生理学会   代議員   Domestic

    2021.4 - 2025.3   

Academic Activities

  • Screening of academic papers

    Role(s)： Peer review

    2021

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    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：2

  • Screening of academic papers

    Role(s)： Peer review

    2020

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    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：2

  • シンポジスト

    第41回日本生物学的精神医学会  （ Japan ） 2019.6

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    Type：Competition, symposium, etc. 

  • シンポジスト

    第14回日本統合失調症学会  （ Japan ） 2019.4

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    Type：Competition, symposium, etc. 

  • Screening of academic papers

    Role(s)： Peer review

    2019

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    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：3

  • シンポジスト

    第31回日本生物学的精神医学会  （ Japan ） 2009.4

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    Type：Competition, symposium, etc. 

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Research Projects

  • Cross frequency coupling on EEG in schizophrenia

    Grant number：21K07482  2021 - 2023

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Hirano Shogo

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    Authorship：Principal investigator  Grant type：Scientific research funding

    We evaluated resting state and 40Hz auditory steady state response (ASSR) with EEG in 61 patients with schizophrenia (SZ) and 62 healthy control subjects (HC). SZ showed decreased phase locking factor (PLF) on ASSR condition compared to HC. Regarding cross-frequency coupling, firstly, SZ showed decreased phase amplitude coupling (PAC) between 3-7Hz phase and 57-100Hz amplitude. Secondly, SZ showed decreased amplitude amplitude coupling (AAC) between 3-9Hz amplitude and 30-100Hz amplitude.

    CiNii Research

  • 統合失調症における周波数間カップリング-脳磁図研究-

    Grant number：18K07602  2018 - 2020

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 統合失調症患者における感覚ゲーティング異常の詳細検討-脳磁図研究-

    Grant number：25861016  2013 - 2015

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 統合失調症患者における感覚ゲーティング異常の詳細検討-脳磁図研究-

    2013 - 2015

    武田科学振興財団　医学系研究奨励（精神・神経・脳領域）

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    Authorship：Principal investigator  Grant type：Contract research

  • 発症前後の統合失調症における聴覚誘発神経振動（ASSR）の経時変化の検討

    2013 - 2014

    先進医薬研究振興財団　精神薬療分野　海外留学助成

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    Authorship：Principal investigator  Grant type：Contract research

  • 統合失調症患者における感覚ゲーティング異常の詳細検討 –脳磁図研究-

    2012 - 2013

    先進医薬研究振興財団　精神薬料分野　若手研究者助成

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    Authorship：Principal investigator  Grant type：Contract research

  • 統合失調症患者における音声処理についての研究

    2011 - 2012

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

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    Authorship：Principal investigator  Grant type：Scientific research funding

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Travel Abroad

  • 2017.11

    Staying countory name 1：United States   Staying institution name 1：Neural Dynamics Laboratory, Research Service, Veterans Affairs Boston Healthcare System and Department of Psychiatry, Harvard Medical School

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Clinical Internal Medicine / Psychiatry and Neuroscience

Clinician qualification

  • 精神保健指定医

    厚生労働省

  • Specialist

    The Japanese Society of Psychiatry and Neurology（JSPN）

  • Preceptor

    The Japanese Society of Psychiatry and Neurology（JSPN）

Year of medical license acquisition

  • 2000