Updated on 2024/10/02

Information

 

写真a

 
NOBUKUNI KEIKO
 
Organization
Kyushu University Hospital Operating Rooms Assistant Professor
School of Medicine Department of Medicine(Concurrent)
Title
Assistant Professor
Contact information
メールアドレス
Tel
0926425714
Profile
手術麻酔業務。術前外来。医学部学生の臨床実習、講義。初期研修医・後期研修医への指導。院内看護師への講義。
External link

Degree

  • None

Research Interests・Research Keywords

  • Research theme:Effect of Flumazenil on Postoperative Memory Retention Time after General Anesthesia with Remimazolam: A Randomized Controlled Trial

    Keyword:remimazolam,flumazenil

    Research period: 2023.1 - 2024.5

Papers

  • Recovery of memory retention after anesthesia with remimazolam:an exploratory, randomized, open, propofol-controlled,single-center clinical trial Reviewed International journal

    Keiko Nobukuni, Kazuhiro Shirozu, Aiko Maeda, Kouta Funakoshi, Midoriko Higashi, Ken Yamaura

    JA Clin Rep.   2023.7

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Redistributional Hypothermia Prevention by Prewarming with Forced-Air: Exploratory, Open, Randomized, Clinical Trial of Efficacy

    Shirozu, K; Nobukuni, K; Maki, J; Nagamatsu, K; Tanaka, R; Oya, K; Funakoshi, K; Higashi, M; Yamaura, K

    THERAPEUTIC HYPOTHERMIA AND TEMPERATURE MANAGEMENT   13 ( 2 )   55 - 61   2023.6   ISSN:2153-7658 eISSN:2153-7933

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    Language:English   Publisher:Therapeutic Hypothermia and Temperature Management  

    Avoiding redistributional hypothermia that decreases core temperature by 0.5-1.5°C within the 1st hour of surgery is difficult. The efficacy of prewarming using a forced-air warming (FAW) device with a lower-body blanket on redistribution hypothermia during epidural procedures have not been investigated. After ethics approval, 113 patients undergoing laparoscopic surgery under general anesthesia combined with epidural anesthesia were enrolled. Intervention (prewarming) group patients who were warmed from operating room entry, including during epidural anesthesia, was compared with the control group that was warmed from just before surgery started. In total, 104 patients (52, control; 52, prewarming) were analyzed. In the prewarming group, compared to the control group, the core temperature 20 minutes after anesthesia induction (36.9 ± 0.4 vs. 37.1 ± 0.4°C, p < 0.02) was significantly higher. The core temperature was higher in the prewarming group than in the control group until 3 hours after the surgery. In the prewarming group, compared to the control group, the core temperature-time integral below baseline till 180 minutes after surgery start (65.1 ± 64.0 vs. 8.1 ± 18.6°C/min, p < 0.0001) or 30 minutes after anesthesia induction (5.3 ± 6.2 vs. 2.0 ± 4.7°C/min, p < 0.0001) were significantly smaller. Postoperative shivering was comparable between the groups. Prewarming during epidural catheter insertion with a FAW device could safely prevent a core temperature decrease induced by redistribution or heat loss without additional preparation, effort, space, or time requirements.

    DOI: 10.1089/ther.2022.0009

    Web of Science

    Scopus

    PubMed

  • Comparison of Changes in Chest Wall Mechanics and Respiratory Timing Between Patient-Controlled Epidural Analgesia and Intravenous Patient-Controlled Analgesia After Laparoscopic Gastrectomy: A Randomized Controlled Trial

    Asada, M; Nobukuni, K; Yoshino, J; Fujimura, N

    CUREUS JOURNAL OF MEDICAL SCIENCE   15 ( 4 )   e37276   2023.4   ISSN:2168-8184 eISSN:2168-8184

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  • Neurological sedative indicators during general anesthesia with remimazolam Reviewed International journal

    Kazuhiro Shirozu, Keiko Nobukuni, Shota Tsumura, Kazuya Imura, Kosuke Nakamura, Shinnosuke Takamori, Midoriko Higashi, Ken Yamaura

    J Anesth.   36 ( 2 )   194 - 200   2022.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Comparison of the occurrence of postoperative shivering between sevoflurane and desflurane anesthesia Reviewed International journal

    Kazuhiro Shirozu, Keiko Nobukuni, Kaoru Umehara, Masako Nagamatsu, Midoriko Higashi, Ken Yamaura

    Ther Hypothermia Temp Manag.   12 ( 3 )   177 - 181   2022.1   ISSN:2153-7658 eISSN:2153-7933

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/ther.2021.0029

    Web of Science

    Scopus

    PubMed

  • Anesthetic management of cesarean section in a patient with Takayasu’s arteritis: A case report Reviewed International journal

    8 ( 1 )   2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

  • The effect of remimazolam on postoperative memory retention and delayed regeneration in breast surgery patients: Rationale and design of an exploratory randomized, open, propofol-controlled, single-canter clinical trial: A study protocol Reviewed International journal

    Kazuhiro Shirozu, Keiko Nobukuni, Kouta Funakoshi, Taizo Nakamura, Makoto Sumie, Midoriko Higashi, Ken Yamaura

    Medicine   100 ( 48 )   2021.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Anesthetic management using low fraction of inspiratory oxygen for living donor liver transplantation in a patient with hepatopulmonary syndrome complicated by interstitial pneumonia: a case report Reviewed International journal

    Keita Takahashi, Kazuya Imura, Keiko Nobukuni, Shoichi Sasaki, Taichi Nagano, Noboru Harada, Tomoharu Yoshizumi, Midoriko Higashi, Ken Yamaura

    Transplantation Proceedings   53 ( 8 )   2556 - 2558   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Retrolaminar versus epidural block for postoperative analgesia after minor video-assisted thoracic surgery:a retrospective, matched, non-inferiority study. Reviewed International journal

    Keiko Nobukuni, Mariko Hatta, Toshiaki Nakagaki, Jun Yoshino, Toshiro Obuchi, Naoyuki Fujimura

    J Thorac Dis.   13 ( 5 )   2758 - 2767   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

  • 閉塞性肥大型心筋症合併患者に対する生体腎移植術の麻酔経験 Reviewed

    信國 桂子、八田 万里子、中垣 俊明、吉野 淳、藤村 直幸

    麻酔   70 ( 6 )   651 - 655   2021.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • バルーン大動脈弁形成術後に消化管手術を行った重症先天性大動脈弁狭窄症の1症例 Reviewed

    篠塚 翔、吉野 淳、石橋 忠幸、信國 桂子、八田 万里子、藤村 直幸

    麻酔   69 ( 12 )   1308 - 1312   2020.12

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 単心室に対するmodified Blalock-Taussing shuntに連続的中心静脈血酸素飽和度モニタリングが有用であった1症例 Reviewed

    浅田 雅子、信國 桂子、平本 有美、吉野 淳

    麻酔   69 ( 9 )   1003 - 1008   2020.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 外傷性肋骨骨折に対し超音波ガイド下持続椎弓後面ブロックにて疼痛管理を行った1症例 Reviewed

    橋本卓磨、犬塚愛美、信國桂子、八田万里子、吉野淳、藤村直幸

    日本救急医学会雑誌   31 ( 2 )   53 - 58   2020.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 低用量レミフェンタニル持続投与による硬膜外穿刺時の和痛 Reviewed

    信國 桂子、坂本 陽子、前田 祥範、宮川 貴圭

    麻酔   62 ( 5 )   580 - 582   2013.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

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Presentations

  • 筋電図方式筋弛緩モニタリングが手術体位により困難であった一症例

    @信國桂子、@白水和宏、@東みどり子、@山浦健

    第45回日本手術医学会総会  2023.11 

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    Event date: 2023.11

    Language:Japanese  

    Country:Japan  

  • Redistributional hypothermia prevention by pre-warming with forced-air during epidural anesthesia: exploratory, open, randomized, clinical trial of efficacy and safety International conference

    Keiko Nobukuni, Kazuhiro Shirozu, Kanako Nagamatsu, Ryudo Tanaka, Kaiki Oya, Midoriko Higashi, Ken Yamaura

    ANESTHESIOLOGY 2022 annual meeting  2022.10 

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    Event date: 2022.10

    Language:English  

    Country:United States  

  • レミマゾラムが健忘に及ぼす影響-プロポフォール対照探索的オープンランダム化比較試験-

    信國桂子、古川愛菜、白水和宏、前田愛子、東みどり子、山浦健

    九州麻酔科学会第60回大会  2022.9 

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    Event date: 2022.9 - 2022.10

    Language:Japanese  

    Country:Japan  

  • Postoperative shivering following sevoflurane and desflurane anesthesia International conference

    Keiko Nobukuni, Kazuhiro Shirozu, Kaoru Umehara, Midoriko Higashi, Ken Yamaura

    Euroanaesthesia2021  2021.12 

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    Event date: 2021.12

    Language:English  

    Country:Germany  

  • 進行性骨化性線維異形成症の麻酔経験

    谷口純彬、信國桂子、白水和宏、東みどり子、山浦健

    九州麻酔科学会第59回大会  2021.9 

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    Event date: 2021.9 - 2021.10

    Language:Japanese  

    Country:Japan  

  • 胸腔鏡下手術における硬膜外麻酔と超音波ガイド下椎弓後面・脊柱起立筋膜面ブロックの術後鎮痛効果

    信國桂子、藤村直幸、八田万里子、吉野淳

    第46回日本集中治療学会学術集会  2019.3 

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    Event date: 2019.3

    Language:Japanese  

    Country:Japan  

  • 閉塞性肥大型心筋症合併患者に対する生体腎移植術の麻酔経験

    信國 桂子、藤村 直幸、石橋 忠幸、八田 万里子、吉野 淳

    九州麻酔科学会第56回大会  2018.9 

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    Event date: 2018.9

    Language:Japanese  

    Country:Japan  

  • Failed Fontan患者に対する非心臓手術の麻酔経験

    信國桂子、八田万里子、吉野淳

    日本心臓血管麻酔学会第23学術大会  2018.9 

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    Event date: 2018.9

    Language:Japanese  

    Country:Japan  

  • 釀膿胸膜切除術に対する超音波ガイド下retrolaminar blockの術後鎮痛効果

    信國桂子、藤村 直幸、田中 万里子、中垣 俊明、吉野 淳、漢那 朝雄、財津 昭憲

    第45回日本集中治療医学会学術集会  2018.2 

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    Event date: 2018.2

    Language:Japanese  

    Country:Japan  

  • アンダーボディブランケットは腹部手術において高い保温効果を発揮する

    信國桂子、宮崎良平、外須美夫

    第64回日本麻酔科学会学術集会  2017.6 

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    Event date: 2017.6

    Language:Japanese  

    Country:Japan  

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Professional Memberships

  • 日本麻酔科学会、日本集中治療医学会、日本心臓血管麻酔学会

Research Projects

  • 異常低血圧を回避する循環作動薬・輸液量自動調節ソフトウェアの探索的臨床試験

    2024.1 - 2024.3

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    Authorship:Coinvestigator(s) 

Outline of Social Contribution and International Cooperation activities

  • 救命救急士の気管挿管実習