Updated on 2024/07/28

Information

 

写真a

 
ITOH SHINJI
 
Organization
Kyushu University Hospital Liver Surgery Lecturer
School of Medicine Department of Medicine(Joint Appointment)
Title
Lecturer
Profile
【略歴】平成12年に九州大学第二外科に入局。2年間の一般外科の研修後、九州大学第二外科医員として臨床・研究に従事。肝細胞癌に関する基礎的および臨床的研究を行い、学位を習得した。九州大学病院および関連病院にて消化器癌の診療に従事した。特に肝胆膵悪性腫瘍に対する外科手術および化学療法について専門的に取り組んでいる。平成26年からは九州大学大学院消化器・総合外科の助教、平成29年より助教講師、令和3年より講師、令和5年より診療准教授として肝胆膵疾患領域の外科治療および薬物療法、肝移植の臨床・研究および学生、研修医、大学院生の教育を行っている。 【学会活動】日本外科学会、日本消化器外科学会(評議員)、日本肝胆膵外科学会(評議員)、日本肝臓学会(代議員、支部評議員)、日本胆道学会、日本膵臓学会、日本移植学会(代議員)、日本消化器病学会(学会評議員、支部評議員)、日本癌治療学会(代議員)、日本癌学会(評議員)、日本内視鏡外科学会(評議員)、日本臨床外科学会(評議員)、日本消化器癌発生学会(評議員)、日本がん分子標的治療学会(評議員)、日本がん転移学会、日本外科感染症学会、日本腹部救急医学会(評議員)、日本酸化ストレス学会(評議員)、日本門脈圧亢進症学会(評議員)、日本バイオセラピィ学会、日本肝癌研究会、日本肝がん分子標的治療研究会(世話人)、手術手技研究会、九州外科学会(評議員)

Degree

  • PhD

Research Interests・Research Keywords

  • Research theme:Intratumoral heterogeneity in HBP malignancy

    Keyword:heterogeneity

    Research period: 2020.4

  • Research theme:Immunooncology in HBP malignancy

    Keyword:immunooncology, biomarker

    Research period: 2017.4

  • Research theme:Role of stress response in HBP malignancy

    Keyword:liver cancer, biliary cancer, pancreatic cancer, stress response、nrf2、ferroptosis

    Research period: 2016.4

  • Research theme:Cancer metabolism of HBP surgery

    Keyword:cancer metabolism

    Research period: 2016.4

  • Research theme:Role of microRNA on tumor progression in HBP surgery

    Keyword:micro RNA

    Research period: 2015.4

  • Research theme:Functional Remnant Liver Assessment Predicts Liver-Related Morbidity after Hepatic Resection in Patients with Hepatocellular Carcinoma

    Keyword:Functional remnant liver assessment, morbidity, hepatic resection

    Research period: 2015.4

  • Research theme:Role of Sarcopenia and frailty in patients with liver disease or HBP malignancy

    Keyword:sarcopenia, frailty, physical performance

    Research period: 2015.4

  • Research theme:Efficacy of liver resection

    Keyword:liver resection

    Research period: 2014.4

  • Research theme:Impact of liver transplantation on outcome

    Keyword:liver transplantation

    Research period: 2014.4

Awards

  • 第3回 IJCO Best Reviewer賞

    2023.10   日本癌治療学会  

  • 第2回 IJCO Best Reviewer賞

    2022.11  

  • 福岡県医学会賞奨励賞

    2022.3  

  • 日本消化癌発生学会大原毅賞

    2020.11   日本消化器癌発生学会  

  • 日本肝臓学会冠Award

    2019.11   日本肝臓学会  

  • 日本医師会医学研究奨励賞

    2019.11   日本医師会  

  • 福岡医学会総会一般演題優秀賞

    2019.2   福岡県医師会  

  • 日本肝臓学会研究奨励賞

    2018.6   日本肝臓学会  

  • 日本外科学会研究奨励賞

    2013.4   日本外科学会  

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Papers

  • Clinical effectiveness of surgical treatment after lenvatinib administration for hepatocellular carcinoma. Invited Reviewed International journal

    Itoh S, Toshida K, Morita K, Kurihara T, Nagao Y, Tomino T, Toshima T, Harada N, Mori M, Yoshizumi T.

    Int J Clin Oncol.   2022.11

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  • Impact of Metabolic Activity in Hepatocellular Carcinoma: Association With Immune Status and Vascular Formation Reviewed International journal

    Itoh, Shinji; Yoshizumi, Tomoharu; Kitamura, Yoshiyuki; Yugawa, Kyohei; Iseda, Norifumi; Shimagaki, Tomonari; Nagao, Yoshihiro; Toshima, Takeo; Harada, Noboru; Kohashi, Kenichi; Baba, Shingo; Ishigami, Kousei; Oda, Yoshinao; Mori, Masaki

    HEPATOLOGY COMMUNICATIONS   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/hep4.1715

  • Impact of Immune Response on Outcomes in Hepatocellular Carcinoma: Association With Vascular Formation Reviewed International journal

    Itoh, Shinji; Yoshizumi, Tomoharu; Yugawa, Kyohei; Imai, Daisuke; Yoshiya, Shohei; Takeishi, Kazuki; Toshima, Takeo; Harada, Noboru; Ikegami, Toru; Soejima, Yuji; Kohashi, Kenichi; Oda, Yoshinao; Mori, Masaki

    HEPATOLOGY   72 ( 6 )   1987 - 1999   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/hep.31206

  • Impact of portal-phase signal intensity of dynamic gadoxetic acid-enhanced magnetic resonance imaging in hepatocellular carcinoma Reviewed International journal

    Tomino T, Itoh S*, Okamoto D, Yoshiya S, Nagao Y, Harada N, Fujita N, Ushijima Y, Ishigami K, Yoshizumi T

    J Hepatobiliary Pancreat Sci.   30 ( 9 )   1089 - 1097   2024.9

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    DOI: doi: 10.1002/jhbp.1345

  • Association of gut microbiota with portal vein pressure in patients with liver cirrhosis undergoing living donor liver transplantation Reviewed International journal

    Toshida K, Itoh S*, Kosai-Fujimoto Y, Ishikawa T, Nakayama Y, Tsutsui Y, Iseda N, Izumi T, Bekki Y, Yoshiya S, Toshima T, Nakamuta M, Yoshizumi T

    JGH Open   7 ( 12 )   982 - 989   2023.12

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    DOI: doi: 10.1002/jgh3.13018

  • Effect of duration of adjuvant chemotherapy with S-1 (6 versus 12 months) for resected pancreatic cancer: the multicenter clinical randomized phase II postoperative adjuvant chemotherapy S-1 (PACS-1) trial Reviewed International journal

    Kayashima H, Itoh S*, Shimokawa M, Hayashi H, Takamori H, Fukuzawa K, Ninomiya M, Araki K, Yamashita Y-i, Sugimachi K, Uchiyama H, Morine Y, Utsunomiya T, Uwagawa T, Maeda T, Baba H, Yoshizumi T

    Int J Clin Oncol.   28 ( 11 )   1520 - 1529   2023.11

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    DOI: doi: 10.1007/s10147-023-02399-7

  • Effect of Early Enteral Nutrition on Graft Loss After Living Donor Liver Transplantation: A Propensity Score Matching Analysis Reviewed International journal

    Tomino T, Harada N, Toshida K, Tomiyama T, Kosai Y, Kurihara T, Yoshiya S, Takeishi K, Toshima T, Nagao Y, Morita K, Iguchi T, Itoh S, Yoshizumi T

    Transplant Proc.   55 ( 9 )   2164 - 2170   2023.9

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    DOI: doi:10.1016/j.transproceed.2023.07.029

  • Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma Reviewed International journal

    Hiromatsu M, Toshida K, Itoh S*, Harada N, Kohashi K, Oda Y, Yoshizumi T

    Ann Surg Oncol.   30 ( 13 )   8675 - 8689   2023.9

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    DOI: doi: 10.1245/s10434-023-14053-7

  • Preoperative HALP score is a prognostic factor for intrahepatic cholangiocarcinoma patients undergoing curative hepatic resection: association with sarcopenia and immune microenvironment Reviewed International journal

    Toshida K, Itoh S*, Nakayama Y, Tsutsui Y, Kosai-Fujimoto Y, Tomino T, Yoshiya S, Nagao Y, Harada N, Kohashi K, Oda Y, Yoshizumi T

    Int J Clin Oncol.   28 ( 8 )   1082 - 1091   2023.8

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    DOI: doi: 10.1007/s10147-023-02358-2

  • Clinical significance of circulating-tumour DNA analysis by metastatic sites in pancreatic cancer Reviewed International journal

    Umemoto K, Sunakawa Y, Ueno M, Furukawa M, Mizuno N, Sudo K, Kawamoto Y, Kajiwara T, Ohtsubo K, Okano N, Matsuhashi N, Itoh S, Matsumoto T, Shimizu S, Otsuru T, Hasegawa H, Okuyama H, Ohama H, Moriwaki T, Ohta T, Odegaard JI, Nakamura Y, Bando H, Yoshino T, Ikeda M, Morizane C

    Br J Cancer   128 ( 8 )   1603 - 1608   2023.8

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    DOI: doi: 10.1038/s41416-023-02189-y.

  • Clinical association between intraoperative ICG fluorescence imaging pattern, preoperative Gd-EOB-DTPA-enhanced MRI findings and histological differentiation in hepatocellular carcinoma Reviewed International journal

    TominoT, Itoh S*, Fujita N, Okamoto D, Nakayama Y, Toshida K, Tomiyama T, Tsutsui Y, Kosai Y, Kuri

    Hepatol Res.   53 ( 8 )   723 - 736   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi: 10.1111/hepr.13902

  • The hemoglobin, albumin, lymphocyte, and platelet score is a prognostic factor for Child-Pugh A patients undergoing curative hepatic resection for single and small hepatocellular carcinoma Reviewed International journal

    Toshida K, Itoh S*, Kayashima H, Nagao Y, Yoshiya S, Tomino T, Fujimoto YK, Tsutsui Y, Nakayama Y, Harada N, Yoshizumi T

    Hepatol Res.   53 ( 6 )   522 - 530   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi: 10.1111/hepr.13885

  • Clinical Significance of Signal Regulatory Protein Alpha (SIRPα) Expression in Hepatocellular Carcinoma Reviewed International journal

    30 ( 6 )   3378 - 3389   2023.6

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    DOI: doi: 10.1245/s10434-022-13058-y

  • Prognostic significance for recurrence of FGFR2 in intrahepatic cholangiocarcinoma patients undergoing curative hepatic resection Reviewed International journal

    Toshida K, Itoh S*, Yugawa K, Kosai Y, Tomino T, Yoshiya S, Nagao Y, Kayashima H, Harada N, Kohashi K, Oda Y, Yoshizumi T

    Hepatol Res.   53 ( 5 )   432 - 439   2023.5

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    DOI: doi: 10.1111/hepr.13875.

  • A third dose of the BNT162b2 mRNA vaccine sufficiently improves the neutralizing activity against SARS-CoV-2 variants in liver transplant recipients Reviewed International journal

    Tomiyama T, Suzuki R, Harada N, Tamura T, Toshida K, Kosai-Fujimoto Y, Tomino T, Yoshiya S, Nagao Y, Takeishi K, Itoh S, Kobayashi N, Ito H, Yoshio S, Kanto T, Yoshizumi T, Fukuhara T

    Front Cell Infect Microbiol.   13   1197349   2023.5

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    DOI: doi: 10.3389/fcimb.2023.1197349

  • Textbook outcome in the laparoscopic cholecystectomy of acute cholecystitis Reviewed International journal

    Iseda N, Iguchi T, Itoh S*, Sasaki S, Honboh T, Yoshizumi T, Sadanaga N, Matsuura H

    Asian J Endosc Surg.   16 ( 4 )   741 - 746   2023.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi: 10.1111/ases.13238

  • Cancer-associated fibroblasts promote tumor cell growth via miR-493-5p in intrahepatic cholangiocarcinoma Invited Reviewed International journal

    Toshida K, Itoh S*, Harada N, Morinaga A, Yugawa K, Tomiyama T, Kosai-Fujimoto Y, Tomino T, Kurihara T, Nagao Y, Morita K, Oda Y, Yoshizumi T

    Cancer Sci.   114 ( 3 )   937 - 947   2023.3

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    DOI: doi: 10.1111/cas.15644

  • Predictive Factors for the Resectable Type of Hepatocellular Carcinoma Recurrence After Living Donor Liver Transplant Reviewed International journal

    Kurihara T, Harada N, Morinaga A, Tomiyama T, Toshida K, Kosai Y, Tomino T, Toshima T, Nagao Y, Morita K, Itoh S, Yoshizumi T

    Transplant Proc.   55 ( 1 )   191 - 196   2023.1

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    DOI: doi: 10.1016/j.transproceed.2022.09.031

  • Preoperative serum brain-derived neurotrophic factor as a predictive biomarker for sepsis after living-donor liver transplantation Reviewed International journal

    Tsutsui Y, Yoshio S, Tomiyama T, Shimagaki T, Itoh S, Harada N, Yoshida Y, Yoshikawa S, Kakazu E, Kanto T, Yoshizumi T.

    Hepatol Res.   53 ( 1 )   72 - 83   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi: 10.1111/hepr.13834

  • Comparison of Efficacy and Safety of Atezolizumab Plus Bevacizumab and Lenvatinib as First-Line Therapy for Unresectable Hepatocellular Carcinoma: A Propensity Score Matching Analysis. Reviewed International journal

    Niizeki T, Tokunaga T, Takami Y, Wada Y, Harada M, Shibata M, Nakao K, Sasaki R, Hirai F, Shakado S, Yoshizumi T, Itoh S, Yatsuhashi H, Bekki S, Ido A, Mawatari S, Honda K, Sugimoto R, Senju T, Takahashi H, Kuwashiro T, Maeshiro T, Nakamuta M, Aratake Y, Yamashita T, Otsuka Y, Matsumoto S, Sohda T, Shimose S, Murotani K, Tanaka Y.

    Target Oncol.   2022.11

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  • Low syntaxin 17 expression in donor liver is associated with poor graft prognosis in recipients of living donor liver transplantation. Reviewed International journal

    Tomiyama T, Shimokawa M, Harada N, Toshida K, Morinaga A, Kosai-Fujimoto Y, Tomino T, Kurihara T, Nagao Y, Toshima T, Morita K, Itoh S, Yoshizumi T.

    Hepatol Res   2022.10

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  • Prognostic Impact of Lymphocyte-to-C-Reactive Protein Ratio in Patients Who Underwent Surgical Resection for Pancreatic Cancer. Iseda N, Iguchi T, Hirose K, Itoh S, Honboh T, Sadanaga N, Matsuura H. Reviewed International journal

    Iseda N, Iguchi T, Hirose K, Itoh S, Honboh T, Sadanaga N, Matsuura H.

    Am Surg.   2022.8

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  • Outcomes of living-donor liver transplantation for acute-on-chronic liver failure based on newly proposed criteria in Japan Reviewed International journal

    Toshima T, Harada N, Itoh S, Morita K, Nagao Y, Kurihara T, Tomino T, Kosai-Fujimoto Y, Morinaga A, Tomiyama T, Yoshizumi T.

    Clin Transplant.   2022.8

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  • Impact of JMJD6 on intrahepatic cholangiocarcinoma. Kosai-Fujimoto Y, Itoh S, Yugawa K, Fukuhara T, Okuzaki D, Toshima T, Harada N, Oda Y, Yoshizumi T, Mori M. Reviewed International journal

    Kosai-Fujimoto Y, Itoh S, Yugawa K, Fukuhara T, Okuzaki D, Toshima T, Harada N, Oda Y, Yoshizumi T, Mori M.

    Mol Clin Oncol.   2022.7

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  • Comparison of the prognostic effect of sarcopenia on atezolizumab plus bevacizumab and lenvatinib therapy in hepatocellular carcinoma patients. Reviewed International journal

    Toshida K, Itoh S, Tomiyama T, Morinaga A, Kosai Y, Tomino T, Kurihara T, Nagao Y, Morita K, Harada N, Yoshizumi T.

    JGH Open   2022.7

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  • Up-regulated LRRN2 expression as a marker for graft quality in living donor liver transplantation. Invited Reviewed International journal

    Tomiyama T, Yamamoto T, Takahama S, Toshima T, Itoh S, Harada N, Shimokawa M, Okuzaki D, Mori M, Yoshizumi T.

    Hepatol Commun.   2022.6

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  • Ferroptosis is induced by lenvatinib through fibroblast growth factor receptor-4 inhibition in hepatocellular carcinoma Reviewed International journal

    Iseda N, Itoh S, Toshida K, Tomiyama T, Morinaga A, Shimokawa M, Shimagaki T, Wang H, Kurihara T, Toshima T, Nagao Y, Harada N, Yoshizumi T, Mori M.

    Cancer Sci.   2022.6

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  • Myeloid-derived suppressor cell infiltration is associated with a poor prognosis in patients with hepatocellular carcinoma Reviewed International journal

    Tomiyama T, Itoh S, Iseda N, Toshida K, Morinaga A, Yugawa K, Fujimoto YK, Tomino T, Kurihara T, Nagao Y, Morita K, Harada N, Kohashi K, Oda Y, Mori M, Yoshizumi T.

    Oncol Lett.   2022.5

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  • Association between Sarcopenia and Omega-3 Polyunsaturated Fatty Acid in Patients with Hepatocellular Carcinoma Reviewed International journal

    Itoh S, Nagao Y, Morita K, Kurihara T, Tomino T, Kosai-Fujimoto Y, Harada N, Fujita N, Ushijima Y, Mori M, Yoshizumi T.

    JMA J   2022.4

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  • Impact of Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocellular Carcinoma: Cancer Metabolism and Immune Status Reviewed International journal

    Iseda N, Itoh S, Yoshizumi T, Tomiyama T, Morinaga A, Yugawa K, Shimokawa M, Shimagaki T, Wang H, Kurihara T, Kitamura Y, Nagao Y, Toshima T, Harada N, Kohashi K, Baba S, Ishigami K, Oda Y, Mori M.

    Hepatol Commun.   2022.4

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  • The ratio of serum des-gamma-carboxy prothrombin to tumor volume as a new biomarker for early recurrence of resected hepatocellular carcinoma Reviewed International journal

    Shimagaki T, Yoshizumi T, Itoh S, Iseda N, Tomiyama T, Morinaga A, Wang H, Kurihara T, Nagao Y, Toshima T, Harada N, Kinjo N, Maeda T, Mori M.

    Hepatol Res.   2022.4

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  • Prognostic Impact of the Preoperative Systemic Inflammation Score in Patients With Pancreatic Ductal Adenocarcinoma Reviewed International journal

    Iguchi T, Iseda N, Hirose K, Itoh S, Harada N, Ninomiya M, Sugimachi K, Honboh T, Maeda T, Sadanaga N, Matsuura H.

    Am Surg   2022.4

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  • Clinical effects of the use of the indocyanine green fluorescence imaging technique in laparoscopic partial liver resection. Reviewed International journal

    Itoh S, Tomiyama T, Morinaga A, Kurihara T, Nagao Y, Toshima T, Morita K, Harada N, Mori M, Yoshizumi T.

    Ann Gastroenterol Surg.   2022.3

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  • Mac-2 Binding Protein Glycosylation Isomer as a Prognostic Marker for Hepatocellular Carcinoma With Sustained Virological Response Invited Reviewed International journal

    Harimoto N, Itoh S, Yamanaka T, Hagiwara K, Ishii N, Tsukagoshi M, Watanabe A, Araki K, Yoshizumi T, Shirabe K.

    Anticancer Res.   2022.1

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  • Trends in hepatocellular carcinoma incident cases in Japan between 1996 and 2019 Reviewed International journal

    Nakano M, Yatsuhashi H, Bekki S, Takami Y, Tanaka Y, Yoshimaru Y, Honda K, Komorizono Y, Harada M, Shibata M, Sakisaka S, Shakado S, Nagata K, Yoshizumi T, Itoh S, Sohda T, Oeda S, Nakao K, Sasaki R, Yamashita T, Ido A, Mawatari S, Nakamuta M, Aratake Y, Matsumoto S, Maeshiro T, Goto T, Torimura T.

    Sci Rep.   2022.1

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  • Prognostic significance of preoperative PNI and CA19-9 for pancreatic ductal adenocarcinoma: A multi-institutional retrospective study. Invited Reviewed International journal

    Shinji Itoh, Eiji Tsujita, Kengo Fukuzawa, Keishi Sugimachi, Tomohiri Iguchi, Mizuki Ninomiya, Takashi Maeda, Kiyashi Kajiyama, Eisuke Adachi, Hideaki Uchiyama, Tohru Utsunomiya, Yasuharu Ikeda, Soichirou Maekawa, Takeo Toshima, Noboru Harada, Tomoharu Yoshizumi, Masaki Mori

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]   2021.8

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    DOI: 10.1016/j.pan.2021.08.003

  • Retrospective evaluation of the effect of Ninjin'yoeito in hepatocellular carcinoma patients treated with lenvatinib. Invited Reviewed International journal

    Katsuya Toshida, Shinji Itoh, Tomoharu Yoshizumi, Tomonari Shimagaki, Huanlin Wang, Takeshi Kurihara, Takeo Toshima, Yoshihiro Nagao, Noboru Harada, Kojiro Hata, Yoko Makihara, Hiroyuki Watanabe, Masaki Mori

    Surgery today   2021.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-021-02358-7

  • Lymphocyte-to-C-reactive protein ratio as a prognostic factor for hepatocellular carcinoma. Invited Reviewed International journal

    Norifumi Iseda, Shinji Itoh, Tomoharu Yoshizumi, Takahiro Tomiyama, Akinari Morinaga, Tomonari Shimagaki, Huanlin Wang, Takeshi Kurihara, Takeo Toshima, Yoshihiro Nagao, Noboru Harada, Yoshinao Oda, Masaki Mori

    International journal of clinical oncology   2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10147-021-01985-x

  • Impact and risk factors for skeletal muscle mass loss after hepatic resection in patients with hepatocellular carcinoma. Invited Reviewed International journal

    Shinji Itoh, Tomoharu Yoshizumi, Takahiro Tomiyama, Norifumi Iseda, Akinari Morinaga, Tomonari Shimagaki, Huanlin Wang, Takeshi Kurihara, Yoshihiro Nagao, Takeo Toshima, Noboru Harada, Akihiro Nishie, Kousei Ishigami, Masaki Mori

    JGH open : an open access journal of gastroenterology and hepatology   5 ( 7 )   785 - 792   2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jgh3.12588

  • Lymphocyte-C-reactive protein ratio as a prognostic marker associated with the tumor immune microenvironment in intrahepatic cholangiocarcinoma. Invited Reviewed International journal

    Kyohei Yugawa, Shinji Itoh, Tomoharu Yoshizumi, Akinari Morinaga, Norifumi Iseda, Takeo Toshima, Noboru Harada, Kenichi Kohashi, Yoshinao Oda, Masaki Mori

    International journal of clinical oncology   2021.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10147-021-01962-4

  • Impact of Capicua on Pancreatic Cancer Progression Reviewed International journal

    Yoshiya, Shohei; Itoh, Shinji; Yoshizumi, Tomoharu; Yugawa, Kyohei; Kurihara, Takeshi; Toshima, Takeo; Harada, Noboru; Hashisako, Mikiko; Yonemasu, Hirotoshi; Fukuzawa, Kengo; Oda, Yoshinao; Mori, Masaki

    ANNALS OF SURGICAL ONCOLOGY   28 ( 6 )   3198 - 3207   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-09339-z

  • Identification of SLC38A7 as a Prognostic Marker and Potential Therapeutic Target of Lung Squamous Cell Carcinoma. Invited Reviewed International journal

    Naoki Haratake, Qingjiang Hu, Tatsuro Okamoto, Tomoko Jogo, Gouji Toyokawa, Fumihiko Kinoshita, Tomoyoshi Takenaka, Tetsuzo Tagawa, Norifumi Iseda, Shinji Itoh, Yuichi Yamada, Yoshinao Oda, Mototsugu Shimokawa, Chie Kikutake, Mikita Suyama, Motoko Unoki, Hiroyuki Sasaki, Masaki Mori

    Annals of Surgery   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/SLA.0000000000005001

  • The Significant Prognostic Factors in Prolonged Intensive/High Care Unit Stay After Living Donor Liver Transplantation. Invited Reviewed International journal

    Shohei Yoshiya, Noboru Harada, Takahiro Tomiyama, Kazuki Takeishi, Takeo Toshima, Tomohiro Iguchi, Shinji Itoh, Mizuki Ninomiya, Tomoharu Yoshizumi, Masaki Mori

    Transplantation proceedings   53 ( 5 )   1630 - 1638   2021.6

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    DOI: 10.1016/j.transproceed.2021.02.020

  • Prognostic Impact of Vessels that Encapsulate Tumor Cluster (VETC) in Patients who Underwent Liver Transplantation for Hepatocellular Carcinoma. Invited Reviewed International journal

    Junji Kawasaki, Takeo Toshima, Tomoharu Yoshizumi, Shinji Itoh, Yohei Mano, Huanlin Wang, Norifumi Iseda, Noboru Harada, Yoshinao Oda, Masaki Mori

    Annals of surgical oncology   2021.6

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    DOI: 10.1245/s10434-021-10209-5

  • Feasibility of hepatic resection for liver metastasis of head-and-neck carcinoma or esophageal carcinoma: a multi-center experience. Invited Reviewed International journal

    Takeshi Kurihara, Shinji Itoh, Yasue Kimura, Eiji Oki, Tomoharu Yoshizumi, Mioko Matuo, Ryuji Yasumatsu, Keishi Sugimachi, Masaru Morita, Tetsuya Kusumoto, Kengo Fukuzawa, Naoya Yoshida, Hideo Baba, Masaki Mori

    Surgery today   2021.5

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    DOI: 10.1007/s00595-021-02305-6

  • Prognostic significance of systemic inflammation score in patients who undergo hepatic resection for hepatocellular carcinoma Reviewed International journal

    Inokuchi, Shoichi; Itoh, Shinji; Yoshizumi, Tomoharu; Morinaga, Akinari; Toshima, Takeo; Takeishi, Kazuki; Nagao, Yoshihiro; Harada, Noboru; Ikegami, Toru; Shimokawa, Mototsugu; Mori, Masaki

    LANGENBECKS ARCHIVES OF SURGERY   406 ( 3 )   773 - 779   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00423-021-02103-1

  • Which is better to use "body weight" or "standard liver weight", for predicting small-for-size graft syndrome after living donor liver transplantation? Invited Reviewed International journal

    Takeo Toshima, Tomoharu Yoshizumi, Tomonari Shimagaki, Huanlin Wang, Takeshi Kurihara, Yoshihiro Nagao, Shinji Itoh, Noboru Harada, Masaki Mori

    Annals of gastroenterological surgery   5 ( 3 )   363 - 372   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ags3.12412

  • Myostatin as a fibroblast-activating factor impacts on postoperative outcome in patients with hepatocellular carcinoma. Invited Reviewed International journal

    Sachiyo Yoshio, Tomonari Shimagaki, Ryuki Hashida, Takumi Kawaguchi, Yuriko Tsutsui, Yuzuru Sakamoto, Yuichi Yoshida, Hironari Kawai, Shiori Yoshikawa, Taiji Yamazoe, Taizo Mori, Yosuke Osawa, Shinji Itoh, Moto Fukai, Tomoharu Yoshizumi, Akinobu Taketomi, Masaki Mori, Tatsuya Kanto

    Hepatology research : the official journal of the Japan Society of Hepatology   2021.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13667

  • A no-ligation technique to prevent intraoperative hepatic artery dissection in living-donor liver transplantation Invited Reviewed International journal

    Itoh, Shinji; Yoshizumi, Tomoharu; Harada, Noboru; Toshima, Takeo; Nagao, Yoshihiro; Kurihara, Takeshi; Wang, Huanlin; Shimagaki, Tomonari; Ikegami, Toru; Mori, Masaki

    SURGERY TODAY   2021.4

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    DOI: 10.1007/s00595-021-02276-8

  • ARID1A Deficiency Is Associated With High Programmed Death Ligand 1 Expression in Hepatocellular Carcinoma Reviewed International journal

    Iseda, Norifumi; Itoh, Shinji; Yoshizumi, Tomoharu; Yugawa, Kyohei; Morinaga, Akinari; Tomiyama, Takahiro; Toshima, Takeo; Kohashi, Kenichi; Oda, Yoshinao; Mori, Masaki

    HEPATOLOGY COMMUNICATIONS   5 ( 4 )   675 - 688   2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/hep4.1659

  • Prognostic impact of tumor microvessels in intrahepatic cholangiocarcinoma: association with tumor-infiltrating lymphocytes Reviewed International journal

    Yugawa, Kyohei; Itoh, Shinji; Yoshizumi, Tomoharu; Iseda, Norifumi; Tomiyama, Takahiro; Toshima, Takeo; Harada, Noboru; Kohashi, Kenichi; Oda, Yoshinao; Mori, Masaki

    MODERN PATHOLOGY   34 ( 4 )   798 - 807   2021.4

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    DOI: 10.1038/s41379-020-00702-9

  • Suppression of optineurin impairs the progression of hepatocellular carcinoma through regulating mitophagy Reviewed International journal

    Inokuchi, Shoichi; Yoshizumi, Tomoharu; Toshima, Takeo; Itoh, Shinji; Yugawa, Kyohei; Harada, Noboru; Mori, Hiroyuki; Fukuhara, Takasuke; Matsuura, Yoshiharu; Mori, Masaki

    CANCER MEDICINE   10 ( 5 )   1501 - 1514   2021.3

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    DOI: 10.1002/cam4.3519

  • Obesity is a risk factor for intrahepatic cholangiocarcinoma progression associated with alterations of metabolic activity and immune status Reviewed International journal

    Yugawa, Kyohei; Itoh, Shinji; Iseda, Norifumi; Kurihara, Takeshi; Kitamura, Yoshiyuki; Toshima, Takeo; Harada, Noboru; Kohashi, Kenichi; Baba, Shingo; Ishigami, Kousei; Oda, Yoshinao; Yoshizumi, Tomoharu; Mori, Masaki

    SCIENTIFIC REPORTS   11 ( 1 )   2021.3

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    DOI: 10.1038/s41598-021-85186-6

  • CMTM6 Stabilizes PD-L1 Expression and Is a New Prognostic Impact Factor in Hepatocellular Carcinoma Reviewed International journal

    Yugawa, Kyohei; Itoh, Shinji; Yoshizumi, Tomoharu; Iseda, Norifumi; Tomiyama, Takahiro; Morinaga, Akinari; Toshima, Takeo; Harada, Noboru; Kohashi, Kenichi; Oda, Yoshinao; Mori, Masaki

    HEPATOLOGY COMMUNICATIONS   5 ( 2 )   334 - 348   2021.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/hep4.1643

  • Cancer-associated fibroblasts promote hepatocellular carcinoma progression through downregulation of exosomal miR-150-3p Reviewed International journal

    Yugawa, Kyohei; Yoshizumi, Tomoharu; Mano, Yohei; Itoh, Shinji; Harada, Noboru; Ikegami, Toru; Kohashi, Kenichi; Oda, Yoshinao; Mori, Masaki

    EJSO   47 ( 2 )   384 - 393   2021.2

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    DOI: 10.1016/j.ejso.2020.08.002

  • Simultaneous splenectomy improves outcomes after adult living donor liver transplantation Reviewed International journal

    Yoshizumi, Tomoharu; Itoh, Shinji; Shimokawa, Mototsugu; Inokuchi, Shoichi; Harada, Noboru; Takeishi, Kazuki; Mano, Yohei; Yoshiya, Shohei; Kurihara, Takeshi; Nagao, Yoshihiro; Ikegami, Toru; Soejima, Yuji; Mori, Masaki

    JOURNAL OF HEPATOLOGY   74 ( 2 )   2021.2

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    DOI: 10.1016/j.jhep.2020.08.017

  • Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma Invited Reviewed International journal

    Suzuki, Hideo; Kohjima, Motoyuki; Tanaka, Masatake; Goya, Takeshi; Itoh, Shinji; Yoshizumi, Tomoharu; Mori, Masaki; Tsuda, Mariko; Takahashi, Motoi; Kurokawa, Miho; Imoto, Koji; Tashiro, Shigeki; Kuwano, Akifumi; Kato, Masaki; Okada, Seiji; Nakamuta, Makoto; Ogawa, Yoshihiro

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   2021   2021.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2021/8813410

  • Immune microenvironment in primary and metastatic liver cancers Invited Reviewed International journal

    Itoh, Shinji; Yugawa, Kyohei; Yoshizumi, Tomoharu; Oda, Yoshinao; Mori, Masaki

    HEPATOLOGY RESEARCH   51 ( 1 )   3 - 4   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13607

  • Association of lenvatinib plasma concentration with clinical efficacy and adverse events in patients with hepatocellular carcinoma. Reviewed International journal

    Kojiro Hata, Kimitaka Suetsugu, Nobuaki Egashira, Yoko Makihara, Shinji Itoh, Tomoharu Yoshizumi, Masatake Tanaka, Motoyuki Kohjima, Hiroyuki Watanabe, Satohiro Masuda, Ichiro Ieiri

    Cancer chemotherapy and pharmacology   86 ( 6 )   803 - 813   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00280-020-04178-x

  • Which is better to use "body weight" or "standard liver weight", for predicting small-for-size graft syndrome after living donor liver transplantation? Reviewed International journal

    Toshima, Takeo; Yoshizumi, Tomoharu; Shimagaki, Tomonari; Wang, Huanlin; Kurihara, Takeshi; Nagao, Yoshihiro; Itoh, Shinji; Harada, Noboru; Mori, Masaki

    ANNALS OF GASTROENTEROLOGICAL SURGERY   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ags3.12412

  • Mitochondrial expression of the DNA repair enzyme OGG1 improves the prognosis of pancreatic ductal adenocarcinoma Reviewed International journal

    Inokuchi, Shoichi; Itoh, Shinji; Yoshizumi, Tomoharu; Yugawa, Kyohei; Yoshiya, Shohei; Toshima, Takeo; Takeishi, Kazuki; Iguchi, Tomohiro; Sanefuji, Kensaku; Harada, Noboru; Sugimachi, Keishi; Ikegami, Toru; Kohashi, Kenichi; Taguchi, Kenichi; Yonemasu, Hirotoshi; Fukuzawa, Kengo; Oda, Yoshinao; Mori, Masaki

    PANCREATOLOGY   20 ( 6 )   1175 - 1182   2020.9

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    DOI: 10.1016/j.pan.2020.07.011

  • Use of Mycophenolate Mofetil Suspension as Part of Induction Therapy After Living-Donor Liver Transplant Reviewed International journal

    Harada, Noboru; Yoshizumi, Tomoharu; Yoshiya, Shohei; Takeishi, Kazuki; Toshima, Takeo; Itoh, Shinji; Ikegami, Toru; Fukuda, Mio; Masuda, Satohiro; Mori, Masaki

    EXPERIMENTAL AND CLINICAL TRANSPLANTATION   18 ( 4 )   485 - 490   2020.8

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    DOI: 10.6002/ect.2020.0041

  • Association of inflammatory biomarkers with long-term outcomes after curative surgery for mass-forming intrahepatic cholangiocarcinoma Reviewed

    Masafumi Ohira, Tomoharu Yoshizumi, Kyohei Yugawa, Yukiko Kosai-Fujimoto, Shoichi Inokuchi, Takashi Motomura, Yohei Mano, Takeo Toshima, Shinji Itoh, Noboru Harada, Toru Ikegami, Yuji Soejima, Akinobu Taketomi, Masaki Mori

    Surgery today   50 ( 4 )   379 - 388   2020.4

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    DOI: 10.1007/s00595-019-01905-7

  • Is sarcopenic obesity superior to sarcopenia as a predicting indicator in patients with hepatocellular carcinoma following hepatic resection? Reviewed International journal

    Itoh, Shinji; Yoshizumi, Tomoharu; Mori, Masaki

    HEPATOBILIARY SURGERY AND NUTRITION   9 ( 2 )   202 - 204   2020.4

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    DOI: 10.21037/hbsn.2019.09.14

  • Risk factors for the metabolic syndrome components of hypertension, diabetes mellitus, and dyslipidemia after living donor liver transplantation Reviewed

    Takeo Toshima, Tomoharu Yoshizumi, Shoichi Inokuchi, Yukiko Kosai-Fujimoto, Takeshi Kurihara, Shohei Yoshiya, Yohei Mano, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Yuji Soejima, Mototsugu Shimokawa, Yoshihiko Maehara, Masaki Mori

    HPB   22 ( 4 )   511 - 520   2020.4

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    DOI: 10.1016/j.hpb.2019.08.008

  • Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma Reviewed

    Masahiro Shimokawa, Tomoharu Yoshizumi, Shinji Itoh, Norifumi Iseda, Kazuhito Sakata, Kyohei Yugawa, Takeo Toshima, Noboru Harada, Toru Ikegami, Masaki Mori

    Cancer Science   111 ( 4 )   1228 - 1240   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/cas.14320

  • Living-Donor Liver Transplantation for Patients With Extrahepatic Malignancy A Series of 14 Patients in a Single Institution Reviewed

    Yukiko Kosai-Fujimoto, Tomoharu Yoshizumi, Takahiro Tomiyama, Akinari Morinaga, Norifumi Iseda, Shoichi Inokuchi, Kyohei Yugawa, Shohei Yoshiya, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Masaki Mori

    Transplantation Proceedings   52 ( 3 )   889 - 893   2020.4

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    DOI: 10.1016/j.transproceed.2019.12.041

  • Prognostic impact of 8-hydroxy-deoxyguanosine and its repair enzyme 8-hydroxy-deoxyguanosine DNA glycosylase in hepatocellular carcinoma Reviewed

    Kyohei Yugawa, Shinji Itoh, Tomoharu Yoshizumi, Shohei Yoshiya, Kazuki Takeishi, Takeo Toshima, Noboru Harada, Toru Ikegami, Kenichi Kohashi, Yoshinao Oda, Masaki Mori

    Pathology International   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/pin.12952

  • Prognostic Impact of Osteopenia in Patients Who Underwent Living Donor Liver Transplantation for Hepatocellular Carcinoma Reviewed

    Takeo Toshima, Tomoharu Yoshizumi, Yukiko Kosai-Fujimoto, Shoichi Inokuchi, Shohei Yoshiya, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Yuji Soejima, Masaki Mori

    World journal of surgery   44 ( 1 )   258 - 267   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00268-019-05206-5

  • Predictor of outcome after living donor liver transplantation for patients with hepatocellular carcinoma beyond the Japan criteria Reviewed

    Yusuke Yonemura, Tomoharu Yoshizumi, Shoichi Inokuchi, Yukiko Kosai-Fujimoto, Noboru Harada, Shinji Itoh, Takeo Toshima, Kazuki Takeishi, Shohei Yoshiya, Masaki Mori

    Annals of Gastroenterological Surgery   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ags3.12335

  • Impact of middle hepatic artery reconstruction after living donor liver transplantation using the left lobe Reviewed

    Noboru Harada, Tomoharu Yoshizumi, Hideaki Uchiyama, Toru Ikegami, Shinji Itoh, Kazuki Takeishi, Takeo Toshima, Yoshihiro Nagao, Shohei Yoshiya, Masaki Mori

    Clinical Transplantation   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ctr.13850

  • Surgical Indications for Hepatocellular Carcinoma with Non-hypervascular Hypointense Nodules Detected by Gd-EOB-DTPA-Enhanced MRI Reviewed

    Kazuki Takeishi, Tomoharu Yoshizumi, Shinji Itoh, Kyohei Yugawa, Shohei Yoshiya, Takeo Toshima, Noboru Harada, Toru Ikegami, Akihiro Nishie, Masaki Mori

    Annals of Surgical Oncology   2020.1

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    DOI: 10.1245/s10434-020-08419-4

  • Prognostic nutritional index is superior as a predictor of prognosis among various inflammation-based prognostic scores in patients with hepatocellular carcinoma after curative resection Reviewed

    Daisuke Imai, Takashi Maeda, Mototsugu Shimokawa, Huanlin Wang, Shohei Yoshiya, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Tomoharu Yoshizumi, Masaki Mori

    Hepatology Research   50 ( 1 )   101 - 109   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13431

  • Extensive Thrombectomy as a Legitimate Strategy in Living Donor Liver Transplantation With Advanced Portal Vein Thrombosis Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Yuriko Tsutsui, Noboru Harada, Shinji Itoh, Shohei Yoshiya, Daisuke Imai, Hideaki Uchiyama, Masaki Mori

    Liver Transplantation   25 ( 12 )   1768 - 1777   2019.12

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    DOI: 10.1002/lt.25623

  • The evolution of surgical treatment for gastrointestinal cancers Reviewed

    Yoshihiko Maehara, Yuji Soejima, Tomoharu Yoshizumi, Naoyuki Kawahara, Eiji Oki, Hiroshi Saeki, Tomohiko Akahoshi, Toru Ikegami, Yo ichi Yamashita, Tadashi Furuyama, Keishi Sugimachi, Noboru Harada, Tetsuzo Tagawa, Norifumi Harimoto, Shinji Itoh, Hideto Sonoda, Koji Ando, Yuichiro Nakashima, Yoshihiro Nagao, Nami Yamashita, Yuta Kasagi, Takafumi Yukaya, Takeshi Kurihara, Ryosuke Tsutsumi, Shinkichi Takamori, Shun Sasaki, Tetsuo Ikeda, Yoshikazu Yonemitsu, Takasuke Fukuhara, Hiroyuki Kitao, Makoto Iimori, Yuki Kataoka, Takeshi Wakasa, Masami Suzuki, Koji Teraishi, Yasuto Yoshida, Masaki Mori

    International Journal of Clinical Oncology   24 ( 11 )   1333 - 1349   2019.11

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    DOI: 10.1007/s10147-019-01499-7

  • Elevation of Mac-2 binding protein glycosylation isomer after hepatectomy is associated with post-hepatectomy liver failure, total Pringle time, and renal dysfunction Reviewed

    Daisuke Imai, Takashi Maeda, Huanlin Wang, Kensaku Sanefuji, Hiroto Kayashima, Shohei Yoshiya, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Tomoharu Yoshizumi, Masaki Mori

    Annals of Gastroenterological Surgery   3 ( 5 )   515 - 522   2019.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ags3.12271

  • IFN-γ Promotes Epithelial-Mesenchymal Transition and the Expression of PD-L1 in Pancreatic Cancer Reviewed

    240   115 - 123   2019.8

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    Background: Tumor immune reactions not only provide host defense but also accelerate tumor immune escape and phenotype switching. Here, we examined the association of programmed cell death ligand 1 (PD-L1) expression with epithelial-mesenchymal transition (EMT)–associated markers in pancreatic ductal adenocarcinoma (PDA) within the context of the tumor microenvironment. Materials and methods: PDA samples from 36 patients were analyzed for PD-L1, vimentin, E-cadherin, and Snail expressions and for PDA cell and immune cell infiltration. PD-L1 expression and EMT in PDA cell lines under conditions of altering interferon gamma (IFN-γ) signals were also assessed. Results: Immunohistochemistry revealed a significant correlation between vimentin and PD-L1 expression, whereas double staining showed them to be simultaneously expressed by PDA cells. Positive vimentin expression was associated with the infiltration of a lower number of CD8 + T cells and a higher number of FoxP3 + cells and poor patient prognosis (P = 0.03). PDA tumor cells promoted PD-L1 expression and EMT under the presence of IFN-γ which was inhibited by the signal transducer and activator of transcription (STAT)1 small interfering RNA. Conclusions: Strong correlations were observed between PD-L1 expression, EMT, and the immunosuppressive tumor microenvironment. Targeting STAT1 combined with PD-1/PD-L1 immunotherapy may improve outcomes for patients with PDA.

    DOI: 10.1016/j.jss.2019.02.038

  • The role of DNA repair glycosylase OGG1 in intrahepatic cholangiocarcinoma Reviewed

    Kazuhito Sakata, Tomoharu Yoshizumi, Takuma Izumi, Masahiro Shimokawa, Shinji Itoh, Toru Ikegami, Noboru Harada, Takeo Toshima, Yohei Mano, Masaki Mori

    Anticancer research   39 ( 6 )   3241 - 3248   2019.1

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    DOI: 10.21873/anticanres.13465

  • Efficacy of Neoadjuvant Chemotherapy in Distal Pancreatectomy with En Bloc Celiac Axis Resection (DP-CAR) for Locally Advanced Pancreatic Cancer Reviewed

    Shohei Yoshiya, Kengo Fukuzawa, Shoichi Inokuchi, Yukiko Kosai-Fujimoto, Kensaku Sanefuji, Kentaro Iwaki, Akira Motohiro, Shinji Itoh, Noboru Harada, Toru Ikegami, Tomoharu Yoshizumi, Masaki Mori

    Journal of Gastrointestinal Surgery   2019.1

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    DOI: 10.1007/s11605-019-04324-8

  • Ectopic localization of autophagosome in fatty liver is a key factor for liver regeneration Reviewed

    Yoshihiro Matsumoto, Tomoharu Yoshizumi, Takeo Toshima, Kazuki Takeishi, Takasuke Fukuhara, Shinji Itoh, Toru Ikegami, Yuji Soejima, Masaki Mori

    Organogenesis   15 ( 1 )   24 - 34   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/15476278.2019.1633872

  • Skeletal muscle mass predicts the prognosis of patients with intrahepatic cholangiocarcinoma Reviewed

    Kyohei Yugawa, shinji itoh, Takeshi Kurihara, Shohei Yoshiya, Yohei Mano, kazuki takeishi, Noboru Harada, Toru Ikegami, Yuji Soejima, Masaki Mori, Tomoharu Yoshizumi

    American Journal of Surgery   2019.1

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    DOI: 10.1016/j.amjsurg.2019.03.010

  • Impact of hepatic artery size mismatch between donor and recipient on outcomes after living-donor liver transplantation using the right lobe Reviewed

    Noboru Harada, Tomoharu Yoshizumi, Hideaki Uchiyama, Yuji Soejima, Toru Ikegami, shinji itoh

    Clinical Transplantation   33 ( 1 )   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ctr.13444

  • Feasibility of All-in-One Venoplasty With a Venous Cuff Using an Opened Round Ligament for the Right Lobe Graft in Living Donor Liver Transplantation Reviewed

    Takeo Toshima, Tomoharu Yoshizumi, Masahiro Shimokawa, Toru Ikegami, Noboru Harada, shinji itoh, Yohei Mano, Takashi Motomura, Yuji Soejima, Yoshihiko Maehara

    Liver Transplantation   25 ( 1 )   171 - 175   2019.1

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    DOI: 10.1002/lt.25339

  • Functional Analysis of Human Hepatocytes Isolated From Chimeric Mouse Liver Reviewed

    N. Harimoto, H. Nakagawara, K. Shirabe, Tomoharu Yoshizumi, shinji itoh, Toru Ikegami, Yuji Soejima, Y. Maehara, Y. Ishida, C. Tateno, Y. Tanaka

    Transplantation Proceedings   50 ( 10 )   3858 - 3862   2018.12

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    DOI: 10.1016/j.transproceed.2018.06.035

  • Impact of osteopenia in liver cirrhosis Special reference to standard bone mineral density with age Reviewed

    Takeo Toshima, Tomoharu Yoshizumi, Toru Ikegami, Noboru Harada, shinji itoh, Yohei Mano, Takashi Motomura, Yuji Soejima, Yoshihiko Maehara

    Anticancer research   38 ( 11 )   6465 - 6471   2018.11

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    DOI: 10.21873/anticanres.13009

  • Lymphocyte-to-Monocyte Ratio Is a Predictor of Survival After Liver Transplantation for Hepatocellular Carcinoma Reviewed

    Yohei Mano, Tomoharu Yoshizumi, Kyohei Yugawa, Masafumi Ohira, Takashi Motomura, Takeo Toshima, shinji itoh, Noboru Harada, Toru Ikegami, Yuji Soejima, Yoshihiko Maehara

    Liver Transplantation   24 ( 11 )   1603 - 1611   2018.11

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    DOI: 10.1002/lt.25204

  • Prognostic Significance of Preoperative Controlling Nutritional Status (CONUT) Score in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma A Multi-institutional Study Reviewed

    Norifumi Harimoto, Tomoharu Yoshizumi, Shoichi Inokuchi, shinji itoh, Eisuke Adachi, Yasuharu Ikeda, Hideaki Uchiyama, Tohru Utsunomiya, Kiyoshi Kajiyama, Koichi Kimura, Fumiaki Kishihara, Keishi Sugimachi, Eiji Tsujita, Mizuki Ninomiya, Kengo Fukuzawa, Takashi Maeda, Ken Shirabe, Yoshihiko Maehara

    Annals of Surgical Oncology   25 ( 11 )   3316 - 3323   2018.10

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    DOI: 10.1245/s10434-018-6672-6

  • Serum asunaprevir and daclatasvir concentrations and outcomes in patients with recurrent hepatitis C who have undergone living donor liver transplantation Reviewed

    Noboru Harada, Tomoharu Yoshizumi, Toru Ikegami, shinji itoh, Norihiro Furusho, Masaki Kato, Shinji Shimoda, Takasuke Fukuhara, Yuji Soejima, Yoshihiko Maehara

    Anticancer research   38 ( 9 )   5513 - 5520   2018.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.12885

  • Long-term Outcomes and Risk Factors after Adult Living Donor Liver Transplantation Reviewed

    Daisuke Imai, Tomoharu Yoshizumi, Kazuhito Sakata, Toru Ikegami, shinji itoh, Noboru Harada, Takashi Motomura, Takeo Toshima, Yohei Mano, Yuji Soejima, Yoshihiko Maehara

    Transplantation   102 ( 9 )   e382 - e391   2018.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/TP.0000000000002324

  • Histological architectural classification determines recurrence pattern and prognosis after curative hepatectomy in patients with hepatocellular carcinoma Reviewed

    Hirohisa Okabe, Tomoharu Yoshizumi, Yo Ichi Yamashita, Katsunori Imai, Hiromitsu Hayashi, Shigeki Nakagawa, shinji itoh, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Toru Beppu, Shinichi Aishima, Ken Shirabe, Hideo Baba, Yoshihiko Maehara

    PloS one   13 ( 9 )   2018.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0203856

  • Impact of Splenic Volume and Splenectomy on Prognosis of Hepatocellular Carcinoma Within Milan Criteria After Curative Hepatectomy Reviewed

    Kazuki Takeishi, Hirofumi Kawanaka, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Ken Shirabe, Yoshihiko Maehara

    World Journal of Surgery   42 ( 4 )   1120 - 1128   2018.4

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    DOI: 10.1007/s00268-017-4232-z

  • Potential effect of recombinant thrombomodulin on ischemia–reperfusion liver injury in rats Reviewed

    48 ( 5 )   391 - 396   2018.4

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    Aim: Liver ischemia–reperfusion (I/R) injury is a severe complication of liver surgery. However, the responsible molecular mechanism remains unclear. High-mobility group box 1 (HMGB1) is released from the nuclei of cells and behaves as a damage-associated molecular pattern. The aim of this study is to reveal the roles of HMGB1 and the effects of recombinant thrombomodulin (rTM) in I/R liver injury. Methods: Rats underwent partial hepatic ischemia followed by reperfusion, and changes in HMGB1 were assessed. Recombinant thrombomodulin was used as an inhibitor of HMGB1. Results: In rats with I/R injury, the HMGB1 level significantly decreased in the liver tissue and significantly increased in the serum after surgery (P < 0.001 for both). No difference in the HMGB1 level in the hepatocytes was observed between the rTM(−) group and rTM(+) group after surgery. Conversely, the serum HMGB1 level was significantly lower in the rTM(+) group than the rTM(−) group after surgery (P < 0.001). The levels of tumor necrosis factor-α and interleukin-6 in the liver tissue 24 h after surgery were significantly lower in the rTM(+) group than the rTM(−) group (P < 0.001). The plasma alanine aminotransferase level at 24 h after surgery of the rTM(+) group was significantly decreased after surgery compared with that of the rTM(−) group (P < 0.001). The necrotic area of the liver tissue 24 h after surgery was significantly smaller in the rTM(+) group than the rTM(−) group (P < 0.001). Conclusions: Recombinant thrombomodulin can serve as a treatment for I/R liver injury by inhibiting HMGB1.

    DOI: 10.1111/hepr.13005

  • Associations between antibody to hepatitis B core antigen positivity and outcomes in hepatocellular carcinoma patients undergoing hepatic resection Reviewed

    shinji itoh, Tomoharu Yoshizumi, Takahiro Tomino, Akihisa Nagatsu, Takashi Motomura, Noboru Harada, Norifumi Harimoto, Toru Ikegami, Yuji Soejima, Yoshihiko Maehara

    Hepatology Research   48 ( 3 )   E155 - E161   2018.2

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    DOI: 10.1111/hepr.12939

  • Customization of laparoscopic gastric devascularization and splenectomy for gastric varices based on CT vascular anatomy Reviewed

    Hirofumi Kawanaka, Tomohiko Akahoshi, Yoshihiro Nagao, Nao Kinjo, Daisuke Yoshida, Yoshihiro Matsumoto, Norifumi Harimoto, shinji itoh, Tomoharu Yoshizumi, Yoshihiko Maehara

    Surgical Endoscopy   32 ( 1 )   114 - 126   2018.1

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    DOI: 10.1007/s00464-017-5646-2

  • Slow Gait Speed Is a Risk Factor for Complications After Hepatic Resection Reviewed

    shinji itoh, Tomoharu Yoshizumi, Kazuhisa Sakata, Takashi Motomura, Yohei Mano, Takeo Toshima, Norifumi Harimoto, Noboru Harada, Toru Ikegami, Yuji Soejima, Ryuichi Kusaba, Takahide Kamishima, Akihiro Nishie, Yoshihiko Maehara

    Journal of Gastrointestinal Surgery   2018.1

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    DOI: 10.1007/s11605-018-3993-5

  • Surgery for Hepatocellular Carcinoma in Patients with Child–Pugh B Cirrhosis Hepatic Resection Versus Living Donor Liver Transplantation Reviewed

    1 - 11   2018.1

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    Background: Liver transplantation has been established as the optimal treatment for hepatocellular carcinoma in cirrhotic patients, but hepatic resection is also effective in patients with well-preserved liver function. Determining the suitable surgical treatment for patients with Child–Pugh class B cirrhosis is a more difficult challenge.Methods: We retrospectively compared the results of hepatic resection and living donor liver transplantation for hepatocellular carcinoma in 137 patients with Child–Pugh class B cirrhosis. The procedures were performed at Kyushu University Hospital from April 2014 through October 2016. Results: Patients who underwent hepatic resection were significantly older and had better liver function, larger tumor size, smaller number of tumors, and less surgical stress compared with patients who underwent living donor liver transplantation. The overall survival rate and the recurrence-free survival rate in patients with transplantation were significantly better than that in patients with resection. The multivariate analysis showed that recurrent hepatocellular carcinoma and microvascular invasion were significant prognostic factors for both overall and recurrence-free survival in the hepatic resection group. In the group with protein induced by vitamin K absence or antagonist-II ≥300 mAU/mL, both the overall survival curve and the recurrence-free survival curve in patients with living donor liver transplantation were not significantly different from those in patients with hepatic resection. Conclusions: Living donor liver transplantation for hepatocellular carcinoma in patients with Child–Pugh class B cirrhosis was favorable under the condition of protein induced by vitamin K absence or antagonist-II <300 mAU/mL in selected recipients and donors. Hepatic resection for recurrent hepatocellular carcinoma and excessive blood loss should be avoided in patients with Child–Pugh class B cirrhosis.

    DOI: 10.1007/s00268-018-4493-1

  • Hepatobiliary and Pancreatic Pregnancy induced hepatic veno-occlusive disease requiring liver transplantation Reviewed

    Norifumi Harimoto, K. Yugawa, Toru Ikegami, M. Ohira, Yohei Mano, T. Motomura, Takeo Toshima, shinji itoh, N. Harada, Yuji Soejima, Tomoharu Yoshizumi, Yoshihiko Maehara, Yoshinao Oda

    Journal of Gastroenterology and Hepatology (Australia)   33 ( 1 )   2018.1

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    DOI: 10.1111/jgh.13975

  • Living donor liver transplantation for hepatocellular carcinoma results of prospective patient selection by Kyushu University Criteria in 7 years Reviewed

    Hideaki Uchiyama, shinji itoh, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, Yuji Soejima, Noboru Harada, Kazutoyo Morita, Takeo Toshima, Takashi Motomura, Yoshihiko Maehara

    HPB   19 ( 12 )   1082 - 1090   2017.12

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    DOI: 10.1016/j.hpb.2017.08.004

  • Clinical Outcomes of Living Liver Transplantation According to the Presence of Sarcopenia as Defined by Skeletal Muscle Mass, Hand Grip, and Gait Speed Reviewed

    Norifumi Harimoto, Tomoharu Yoshizumi, T. Izumi, T. Motomura, Noboru Harada, shinji itoh, Toru Ikegami, H. Uchiyama, Yuji Soejima, Akihiro Nishie, T. Kamishima, R. Kusaba, K. Shirabe, Yoshihiko Maehara

    Transplantation Proceedings   49 ( 9 )   2144 - 2152   2017.11

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    DOI: 10.1016/j.transproceed.2017.09.017

  • Prognostic significance of combined albumin–bilirubin and tumor–node–metastasis staging system in patients who underwent hepatic resection for hepatocellular carcinoma Reviewed

    47 ( 12 )   1289 - 1298   2017.11

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    Background: In recent years, the establishment of new staging systems for hepatocellular carcinoma (HCC) has been reported worldwide. The system combining albumin–bilirubin (ALBI) with tumor–node–metastasis stage, developed by the Liver Cancer Study Group of Japan, was called the ALBI-T score. Methods: Patient data were retrospectively collected for 357 consecutive patients who had undergone hepatic resection for HCC with curative intent between January 2004 and December 2015. The overall survival and recurrence-free survival were compared by the Kaplan–Meier method, using different staging systems: the Japan integrated staging (JIS), modified JIS, and ALBI-T. Results: Multivariate analysis identified five poor prognostic factors (higher age, poor differentiation, the presence of microvascular invasion, the presence of intrahepatic metastasis, and blood transfusion) that influenced overall survival, and four poor prognostic factors (the presence of intrahepatic metastasis, serum α-fetoprotein level, blood transfusion, and each staging system (JIS, modified JIS, and ALBI-T score)) that influenced recurrence-free survival. Patients for each these three staging system had a significantly worse prognosis regarding recurrence-free survival, but not with overall survival. The modified JIS score showed the lowest Akaike information criteria statistic value, indicating it had the best ability to predict overall survival compared with the other staging systems. Conclusions: This retrospective analysis showed that, in post-hepatectomy patients with HCC, the ALBI-T score is predictive of worse recurrence-free survival, even when adjustments are made for other known predictors. However, modified JIS is better than ALBI-T in predicting overall survival.

    DOI: 10.1111/hepr.12868

  • Prognostic Significance of Preoperative Controlling Nutritional Status (CONUT) Score in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma Reviewed

    Norifumi Harimoto, Tomoharu Yoshizumi, Kazuhito Sakata, Akihisa Nagatsu, Takashi Motomura, shinji itoh, Noboru Harada, Toru Ikegami, Hideaki Uchiyama, Yuji Soejima, Yoshihiko Maehara

    World Journal of Surgery   41 ( 11 )   2805 - 2812   2017.11

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    DOI: 10.1007/s00268-017-4097-1

  • p62 Promotes Amino Acid Sensitivity of mTOR Pathway and Hepatic Differentiation in Adult Liver Stem/Progenitor Cells Reviewed

    Masakazu Sugiyama, Tomoharu Yoshizumi, Yoshihiro Yoshida, Yuki Bekki, Yoshihiro Matsumoto, Shohei Yoshiya, Takeo Toshima, Toru Ikegami, shinji itoh, Norifumi Harimoto, Shinji Okano, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara

    Journal of Cellular Physiology   232 ( 8 )   2112 - 2124   2017.8

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    DOI: 10.1002/jcp.25653

  • The prognostic impact of programmed cell death ligand 1 and human leukocyte antigen class I in pancreatic cancer Reviewed

    Daisuke Imai, Tomoharu Yoshizumi, Shinji Okano, Hideaki Uchiyama, Toru Ikegami, Norifumi Harimoto, shinji itoh, Yuji Soejima, Shinichi Aishima, Yoshinao Oda, Yoshihiko Maehara

    Cancer Medicine   6 ( 7 )   1614 - 1626   2017.7

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    DOI: 10.1002/cam4.1087

  • Impact and prediction of lymph node involvement in patients with intrahepatic cholangiocarcinoma after curative resection Reviewed

    Noboru Harada, Tomoharu Yoshizumi, Yo Ichi Yamashita, Yuji Soejima, Toru Ikegami, Norifumi Harimoto, shinji itoh, Yoshihiko Maehara

    Anticancer Research   37 ( 7 )   3763 - 3769   2017.7

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    DOI: 10.21873/anticanreS.11751

  • Hepatic stellate cells secreting WFA+-M2BP Its role in biological interactions with Kupffer cells Reviewed

    Yuki Bekki, Tomoharu Yoshizumi, Shinji Shimoda, shinji itoh, Norifumi Harimoto, Toru Ikegami, Atsushi Kuno, Hisashi Narimatsu, Ken Shirabe, Yoshihiko Maehara

    Journal of Gastroenterology and Hepatology (Australia)   32 ( 7 )   1387 - 1393   2017.7

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    DOI: 10.1111/jgh.13708

  • Shape and Enhancement Characteristics of Pancreatic Neuroendocrine Tumor on Preoperative Contrast-enhanced Computed Tomography May be Prognostic Indicators Reviewed

    Hirohisa Okabe, Daisuke Hashimoto, Akira Chikamoto, Morikatsu Yoshida, Katsunobu Taki, Kota Arima, Katsunori Imai, Yoshitaka Tamura, Osamu Ikeda, Takatoshi Ishiko, Hideaki Uchiyama, Toru Ikegami, Norifumi Harimoto, shinji itoh, Yo ichi Yamashita, Tomoharu Yoshizumi, Toru Beppu, Yasuyuki Yamashita, Hideo Baba, Yoshihiko Maehara

    Annals of Surgical Oncology   24 ( 5 )   1399 - 1405   2017.5

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    DOI: 10.1245/s10434-016-5630-4

  • Surgical treatment and outcome of patients with de novo lung cancer after liver transplantation Reviewed

    Fumihiro Shoji, Gouji Toyokawa, Noboru Harada, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tatsuro Okamoto, Yuji Soejima, Tomoharu Yoshizumi, Yoshihiko Maehara

    Anticancer Research   37 ( 5 )   2619 - 2623   2017.5

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    DOI: 10.21873/anticanres.11608

  • Pleural Effusion After Hepatectomy for Hepatocellular Carcinoma Risk Factor Analyses and Its Impact on Oncological Outcomes Reviewed

    Hideaki Uchiyama, Norifumi Harimoto, shinji itoh, Tomoharu Yoshizumi, Toru Ikegami, Yoshihiko Maehara

    World Journal of Surgery   41 ( 4 )   1089 - 1099   2017.4

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    DOI: 10.1007/s00268-016-3826-1

  • Functional remnant liver assessment predicts liver-related morbidity after hepatic resection in patients with hepatocellular carcinoma Reviewed

    shinji itoh, Tomoharu Yoshizumi, Ken Shirabe, Koichi Kimura, Hirohisa Okabe, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Akihiro Nishie, Yoshihiko Maehara

    Hepatology Research   47 ( 5 )   398 - 404   2017.4

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    DOI: 10.1111/hepr.12761

  • Preoperative pancreatic stiffness by real-time tissue elastography to predict pancreatic fistula after pancreaticoduodenectomy Reviewed

    Noboru Harada, Tomoharu Yoshizumi, Takashi Maeda, Hiroto Kayashima, Toru Ikegami, Norifumi Harimoto, shinji itoh, Yoshihiko Maehara

    Anticancer Research   37 ( 4 )   1909 - 1915   2017.4

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    DOI: 10.21873/anticanres.11529

  • Post-hepatectomy refractory ascites in cirrhotic patients with hepatocellular carcinoma Risk factor analysis to overcome this problematic complication Reviewed

    shinji itoh, Hideaki Uchiyama, Yasuharu Ikeda, Kazutoyo Morita, Noboru Harada, Keishi Sugimachi, Hirofumi Kawanaka, Daisuke Korenaga, Tomoharu Yoshizumi, Kenji Takenaka, Yoshihiko Maehara

    Anticancer Research   37 ( 3 )   1381 - 1385   2017.3

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    DOI: 10.21873/anticanres.11459

  • Eversion technique to prevent biliary stricture after living donor liver transplantation in the universal minimal hilar dissection era Reviewed

    Toru Ikegami, Tomonari Shimagaki, Junji Kawasaki, Tomoharu Yoshizumi, Hideaki Uchiyama, Noboru Harada, Norifumi Harimoto, shinji itoh, Yuji Soejima, Yoshihiko Maehara

    Transplantation   101 ( 1 )   e20 - e25   2017.1

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    DOI: 10.1097/TP.0000000000001533

  • Role of autophagy in liver regeneration

    Takeo Toshima, Ken Shirabe, Yoshihiro Matsumoto, Shinji Itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Yoshihiko Maehara

    Autophagy Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging Volume 12   451 - 461   2017.1

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    DOI: 10.1016/B978-0-12-812146-7.00023-8

  • Use of internal jugular vein grafts in reconstructing multiple venous orifices of right hepatic grafts without the middle hepatic vein trunk Reviewed

    Hideaki Uchiyama, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, shinji itoh, Hirohisa Okabe, Yuji Soejima, Yoshihiko Maehara

    Liver Transplantation   23 ( 1 )   110 - 116   2017.1

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    DOI: 10.1002/lt.24644

  • Surgical resection of giant pheochromocytomas arising behind the retrohepatic inferior vena cava Reviewed

    Yuji Soejima, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, shinji itoh, Noboru Harada, Takashi Motomura, Akihisa Nagatsu, Tetsuo Ikeda, Yoshihiko Maehara

    Anticancer Research   37 ( 1 )   277 - 280   2017.1

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    DOI: 10.21873/anticanres.11318

  • Surgical resection for lymph node metastasis after liver transplantation for hepatocellular carcinoma Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Jyunji Kawasaki, Akihisa Nagatsu, Hideaki Uchiyama, Noboru Harada, Norifumi Harimoto, shinji itoh, Takashi Motomura, Yuji Soejima, Yoshihiko Maehara

    Anticancer Research   37 ( 2 )   891 - 896   2017.1

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    DOI: 10.21873/anticanres.11395

  • Left lobe living donor liver transplantation in adults What is the safety limit? Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Kazuhito Sakata, Hideaki Uchiyama, Norifumi Harimoto, Noboru Harada, shinji itoh, Akihisa Nagatsu, Yuji Soejima, Yoshihiko Maehara

    Liver Transplantation   22 ( 12 )   1666 - 1675   2016.12

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    DOI: 10.1002/lt.24611

  • The learning curves in living donor hemiliver graft procurement using small upper midline incision Reviewed

    Toru Ikegami, Norifumi Harimoto, Masahiro Shimokawa, Tomoharu Yoshizumi, Hideaki Uchiyama, shinji itoh, Norihisa Okabe, Kazuhito Sakata, Akihisa Nagatsu, Yuji Soejima, Yoshihiko Maehara

    Clinical Transplantation   30 ( 12 )   1532 - 1537   2016.12

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    DOI: 10.1111/ctr.12850

  • Sarcopenia is a poor prognostic factor following hepatic resection in patients aged 70 years and older with hepatocellular carcinoma Reviewed

    46 ( 12 )   1247 - 1255   2016.11

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    Aim: The present study investigated the effect of sarcopenia on short- and long-term surgical outcomes and identified potential prognostic factors for hepatocellular carcinoma (HCC) following hepatectomy among patients 70 years of age and older. Methods: Patient data were retrospectively collected for 296 consecutive patients who underwent hepatectomy for HCC with curative intent. Patients were assigned to two groups according to age (younger than 70 years, and 70 years and older), and the presence of sarcopenia. The clinicopathological, surgical outcome, and long-term survival data were analyzed. Results: Sarcopenia was present in 112 of 296 (37.8%) patients with HCC, and 35% of patients aged 70 years and older. Elderly patients had significantly lower serum albumin levels, prognostic nutrition index, percentage of liver cirrhosis, and histological intrahepatic metastasis compared with patients younger than 70 years. Overall survival and disease-free survival rates in patients with sarcopenia correlated with significantly poor prognosis in the group aged 70 years and older. Multivariate analysis revealed that sarcopenia was predictive of an unfavorable prognosis. Conclusion: This retrospective analysis revealed that sarcopenia was predictive of worse overall survival and recurrence-free survival after hepatectomy in patients 70 years of age and older with HCC.

    DOI: 10.1111/hepr.12674

  • Inflammation-based prognostic score in patients with living donor liver transplantation for hepatocellular carcinoma Reviewed

    Norifumi Harimoto, Tomoharu Yoshizumi, Tomonari Shimagaki, Akihisa Nagatsu, Takashi Motomura, Noboru Harada, Hirohisa Okabe, shinji itoh, Toru Ikegami, Hideaki Uchiyama, Yuji Soejima, Yoshihiko Maehara

    Anticancer Research   36 ( 10 )   5537 - 5542   2016.10

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    DOI: 10.21873/anticanres.11137

  • The use of left grafts with a replaced or accessory left hepatic artery in adult-to-adult living donor liver transplantation analyses of donor and recipient outcomes Reviewed

    Hideaki Uchiyama, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, shinji itoh, Hirohisa Okabe, Koichi Kimura, Yoshihiko Maehara

    Clinical Transplantation   30 ( 9 )   1021 - 1027   2016.9

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    DOI: 10.1111/ctr.12783

  • Validity of hepatic or pancreatic resection for elderly patients aged 85 years or older at a single community hospital in Japan Reviewed

    shinji itoh, Shunji Kohnoe, Ken Shirabe, Daisuke Yoshida, Hirofumi Kawanaka, Tomoharu Yoshizumi, Toru Ikegami, Yo Ichi Yamashita, Takeshi Kurihara, Yoshihiko Maehara

    Anticancer Research   36 ( 8 )   4289 - 4292   2016.8

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  • Graft selection strategy in adult-to-adult living donor liver transplantation When both hemiliver grafts meet volumetric criteria Reviewed

    Takeshi Kurihara, Tomoharu Yoshizumi, Yoshihiro Yoshida, Toru Ikegami, shinji itoh, Norifumi Harimoto, Mizuki Ninomiya, Hideaki Uchiyama, Hirohisa Okabe, Koichi Kimura, Hirofumi Kawanaka, Ken Shirabe, Yoshihiko Maehara

    Liver Transplantation   22 ( 7 )   914 - 922   2016.7

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    DOI: 10.1002/lt.24431

  • Inquiries About Biomarkers of Acute Liver Failure in Patients Who Underwent Living Donor Liver Transplantation Using a Protein Chip Array Reviewed

    Yo ichi Yamashita, Tomoharu Yoshizumi, Toru Ikegami, Hideaki Uchiyama, Eiji Tsujita, shinji itoh, Norifumi Harimoto, Yuji Soejima, Akinobu Taketomi, Hideo Baba, Yoshihiko Maehara

    Fukuoka Acta Medica   107 ( 7 )   131 - 135   2016.7

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  • Effect of sarcopenic obesity on outcomes of living-donor liver transplantation for hepatocellular carcinoma Reviewed

    shinji itoh, Tomoharu Yoshizumi, Koichi Kimura, Hirohisa Okabe, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Ken Shirabe, Akihiro Nishie, Yoshihiko Maehara

    Anticancer Research   36 ( 6 )   3029 - 3034   2016.6

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  • Relevance of microRNA-18a and microRNA-199a-5p to hepatocellular carcinoma recurrence after living donor liver transplantation Reviewed

    Kazutoyo Morita, Ken Shirabe, Akinobu Taketomi, Yuji Soejima, Tomoharu Yoshizumi, Hideaki Uchiyama, Toru Ikegami, Yo Ichi Yamashita, Keishi Sugimachi, Norifumi Harimoto, shinji itoh, Tetsuo Ikeda, Yoshihiko Maehara

    Liver Transplantation   22 ( 5 )   665 - 676   2016.5

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    DOI: 10.1002/lt.24400

  • CURRENT STATUS OF HEPATOBILIARY PANCREATIC SURGERY FOR ELDERLY PATIENTS Reviewed

    Tomoharu Yoshizumi, Norifumi Harimoto, shinji itoh, Toru Ikegami, Hideaki Uchiyama, Tetsuo Ikeda, Yoshihiko Maehara

    Nihon Geka Gakkai zasshi   117 ( 3 )   174 - 181   2016.5

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  • Diverse basis of β-catenin activation in human hepatocellular carcinoma Implications in biology and prognosis Reviewed

    11 ( 4 )   2016.4

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    Aim: β-catenin signaling is a major oncogenic pathway in hepatocellular carcinoma (HCC). Since β-catenin phosphorylation by glycogen synthase kinase 3β (GSK3β) and casein kinase 1ϵ (CK1ϵ) results in its degradation, mutations affecting these phosphorylation sites cause β-catenin stabilization. However, the relevance of missense mutations in non-phosphorylation sites in exon 3 remains unclear. The current study explores significance of such mutations in addition to addressing the clinical and biological implications of β-catenin activation in human HCC. Methods: Gene alteration in exon3 of CTNNB1, gene expression of β-catenin targets such as glutamate synthetase (GS), axin2, lect2 and regucalcin (RGN), and protein expression of β-catenin were examined in 125 human HCC tissues. Results: Sixteen patients (12.8%) showed conventional missense mutations affecting codons 33, 37, 41, and 45. Fifteen additional patients (12.0%) had other missense mutations in codon 32, 34, and 35. Induction of exon3 mutation caused described β-catenin target gene upregulation in HCC cell line. Interestingly, conventional and non-phosphorylation site mutations were equally associated with upregulation of β-catenin target genes. Nuclear localization of β-catenin was associated with poor overall survival (p = 0.0461). Of these patients with nuclear β-catenin localization, loss of described β-catenin target gene upregulation showed significant poorer overall survival than others (p = 0.0001). Conclusion: This study suggests that both conventional and other missense mutations in exon 3 of CTNNB1 lead to β-catenin activation in human HCC. Additionally, the mechanism of nuclear β-catenin localization without upregulation of described β-catenin target genes might be of clinical importance depending on distinct mechanism.

    DOI: 10.1371/journal.pone.0152695

  • Skeletal muscle mass assessed by computed tomography correlates to muscle strength and physical performance at a liver-related hospital experience Reviewed

    shinji itoh, Ken Shirabe, Tomoharu Yoshizumi, Kazuki Takeishi, Norifumi Harimoto, Toru Ikegami, Hirofumi Kawanaka, Akihiro Nishie, Takahide Kamishima, Yoshihiko Maehara

    Hepatology Research   46 ( 4 )   292 - 297   2016.4

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    DOI: 10.1111/hepr.12537

  • Living donor liver transplantation for intrahepatic arteriovenous fistula with hepatic artery reconstruction using the right gastroepiploic artery Reviewed

    Hideaki Uchiyama, Ken Shirabe, Tomoharu Yoshizumi, Toru Ikegami, Norifumi Harimoto, shinji itoh, Koichi Kimura, Hirohisa Okabe, Yoshihiko Maehara

    Liver Transplantation   22 ( 4 )   552 - 556   2016.4

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    DOI: 10.1002/lt.24377

  • Telaprevir versus simeprevir for the treatment of recurrent hepatitis C after living donor liver transplantation Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Yoshihro Yoshida, Takeshi Kurihara, Norifumi Harimoto, shinji itoh, Masahiro Shimokawa, Takasuke Fukuhara, Ken Shirabe, Yoshihiko Maehara

    Hepatology Research   46 ( 3 )   E136 - E145   2016.3

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    DOI: 10.1111/hepr.12546

  • A Cohort Study for Derivation and Validation of Early Detection of Pancreatic Fistula After Pancreaticoduodenectomy Reviewed

    Kazuki Takeishi, Takashi Maeda, Yo ichi Yamashita, Eiji Tsujita, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Ken Shirabe, Yoshihiko Maehara

    Journal of Gastrointestinal Surgery   20 ( 2 )   385 - 391   2016.2

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    DOI: 10.1007/s11605-015-3030-x

  • Predictors of Benign Status in Liver Tumors Under 3 cm in Diameter Misdiagnosed as Hepatocellular Carcinoma Reviewed

    Koichi Kimura, shinji itoh, Takeshi Kurihara, Yoshihiro Yoshida, Huanlin Wang, Norifumi Harimoto, Akihiro Nishie, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara

    Anticancer Research   36 ( 2 )   793 - 797   2016.2

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  • Impact of recombinant human soluble thrombomodulin for disseminated intravascular coagulation Reviewed

    shinji itoh, Ken Shirabe, Shunji Kohnoe, Noriaki Sadanaga, Kiyoshi Kajiyama, Motoyuki Yamagata, Hideaki Anai, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Yoshihiko Maehara

    Anticancer Research   36 ( 5 )   2493 - 2496   2016.1

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  • Surgical results of pancreaticoduodenectomy for pancreatic ductal adenocarcinoma A multi-institutional retrospective study of 174 patients Reviewed

    Yo Ichi Yamashita, Tomoharu Yoshizumi, Kengo Fukuzawa, Takashi Nishizaki, Eiji Tsujita, Kiyoshi Kajiyama, Yuji Soejima, Motoyuki Yamagata, Kazuharu Yamamoto, Eisuke Adachi, Keishi Sugimachi, Yasuharu Ikeda, Hideaki Uchiyama, Takashi Maeda, shinji itoh, Norifumi Harimoto, Toru Ikegami, Yoshihiko Maehara

    Anticancer Research   36 ( 5 )   2407 - 2412   2016.1

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  • Living Donor Liver Transplantation for Hepatocellular Carcinoma within Milan Criteria in the Present Era Reviewed

    Tomoharu Yoshizumi, Norifumi Harimoto, shinji itoh, Hirohisa Okabe, Koichi Kimura, Hideaki Uchiyama, Toru Ikegami, Tetsuo Ikeda, Yoshihiko Maehara

    Anticancer Research   36 ( 1 )   439 - 445   2016.1

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  • Ischemia-reperfusion injury in fatty liver is mediated by activated NADPH oxidase 2 in rats Reviewed

    Koichi Kimura, Ken Shirabe, Tomoharu Yoshizumi, Kazuki Takeishi, shinji itoh, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Shinji Okano, Yoshihiko Maehara

    Transplantation   100 ( 4 )   791 - 800   2016.1

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    DOI: 10.1097/TP.0000000000001130

  • Impact of recombinant human soluble thrombomodulin for disseminated intravascular coagulation Reviewed

    shinji itoh, Ken Shirabe, Shunji Kohnoe, Noriaki Sadanaga, Kiyoshi Kajiyama, Motoyuki Yamagata, Hideaki Anai, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Yoshihiko Maehara

    Anticancer Research   36 ( 5 )   2493 - 2496   2016.1

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  • Favorable Outcomes of Hepatectomy for Ruptured Hepatocellular Carcinoma Retrospective Analysis of Primary R0-Hepatectomized Patients Reviewed

    Hideaki Uchiyama, Ryosuke Minagawa, shinji itoh, Kiyoshi Kajiyama, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Ken Shirabe, Kenji Takenaka, Yoshihiko Maehara

    Anticancer Research   36 ( 1 )   379 - 385   2016.1

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  • Surgical results of pancreaticoduodenectomy for pancreatic ductal adenocarcinoma A multi-institutional retrospective study of 174 patients Reviewed

    Yo Ichi Yamashita, Tomoharu Yoshizumi, Kengo Fukuzawa, Takashi Nishizaki, Eiji Tsujita, Kiyoshi Kajiyama, Yuji Soejima, Motoyuki Yamagata, Kazuharu Yamamoto, Eisuke Adachi, Keishi Sugimachi, Yasuharu Ikeda, Hideaki Uchiyama, Takashi Maeda, shinji itoh, Norifumi Harimoto, Toru Ikegami, Yoshihiko Maehara

    Anticancer Research   36 ( 5 )   2407 - 2412   2016.1

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  • Living Donor Liver Transplantation for Hepatocellular Carcinoma within Milan Criteria in the Present Era Reviewed

    Tomoharu Yoshizumi, Norifumi Harimoto, shinji itoh, Hirohisa Okabe, Koichi Kimura, Hideaki Uchiyama, Toru Ikegami, Tetsuo Ikeda, Yoshihiko Maehara

    Anticancer Research   36 ( 1 )   439 - 445   2016.1

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  • Ischemia-reperfusion injury in fatty liver is mediated by activated NADPH oxidase 2 in rats Reviewed

    Koichi Kimura, Ken Shirabe, Tomoharu Yoshizumi, Kazuki Takeishi, shinji itoh, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Shinji Okano, Yoshihiko Maehara

    Transplantation   100 ( 4 )   791 - 800   2016.1

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    DOI: 10.1097/TP.0000000000001130

  • Clinicopathologic Features and Outcomes of Non-B, Non-C Hepatocellular Carcinoma After Hepatectomy Reviewed

    Kazuki Takeishi, Takashi Maeda, Ken Shirabe, Eiji Tsujita, Yo ichi Yamashita, Norifumi Harimoto, shinji itoh, Toru Ikegami, Tomoharu Yoshizumi, Yoshihiko Maehara

    Annals of Surgical Oncology   22   1116 - 1124   2015.12

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    DOI: 10.1245/s10434-015-4728-4

  • Risk factors for hepatitis B virus recurrence after living donor liver transplantation A 17-year experience at a single center Reviewed

    Sung Kwan Bae, Shinji Shimoda, Toru Ikegami, Tomoharu Yoshizumi, Norifumi Harimoto, shinji itoh, Yuji Soejima, Hideaki Uchiyama, Ken Shirabe, Yoshihiko Maehara

    Hepatology Research   45 ( 12 )   1203 - 1210   2015.12

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    DOI: 10.1111/hepr.12489

  • Profile of plasma amino acids values as a predictor of sepsis in patients following living donor liver transplantation Special reference to sarcopenia and postoperative early nutrition Reviewed

    Takeo Toshima, Ken Shirabe, Takeshi Kurihara, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Hirofumi Kawanaka, Tetsuo Ikeda, Yoshihiko Maehara

    Hepatology Research   45 ( 12 )   1170 - 1177   2015.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.12484

  • Pancreatic Transection Using Tape Sling and Ultrasonic Aspirator Dissection Technique in Pancreaticoduodenectomy and Distal Pancreatectomy Reviewed

    Hideaki Uchiyama, Kazutoyo Morita, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Ken Shirabe, Kenji Takenaka, Yoshihiko Maehara

    Journal of the American College of Surgeons   221 ( 5 )   e91 - e95   2015.11

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    DOI: 10.1016/j.jamcollsurg.2015.08.005

  • Predictors of the Effectiveness of Prophylactic Drains after Hepatic Resection Reviewed

    Yuki Bekki, Yo Ichi Yamashita, shinji itoh, Norifumi Harimoto, Ken Shirabe, Yoshihiko Maehara

    World Journal of Surgery   39 ( 10 )   2543 - 2549   2015.10

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    DOI: 10.1007/s00268-015-3116-3

  • Indocyanine Green Fluorescent Imaging for Hepatic Resection of the Right Hepatic Vein Drainage Area Reviewed

    Takeshi Kurihara, Yo Ichi Yamashita, Yoshihiro Yoshida, Kazuki Takeishi, shinji itoh, Norifumi Harimoto, Tomoharu Yoshizumi, Ken Shirabe, Tetsuo Ikeda, Yoshihiko Maehara

    Journal of the American College of Surgeons   221 ( 3 )   e49 - e53   2015.9

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    DOI: 10.1016/j.jamcollsurg.2015.05.009

  • The changes in treatment strategies in ABOi living donor liver transplantation for acute liver failure Reviewed

    Mitsuhiro Yasuda, Toru Ikegami, Daisuke Imai, Huanlin Wang, Yuki Bekki, shinji itoh, Tomoharu Yoshizumi, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara

    Journal of Medical Investigation   62 ( 3 )   184 - 187   2015.9

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    DOI: 10.2152/jmi.62.184

  • Optimal changes in portal hemodynamics induced by splenectomy during living donor liver transplantation Reviewed

    Huanlin Wang, Toru Ikegami, Noboru Harada, Tomoharu Yoshizumi, Yuji Soejima, Hideaki Uchiyama, Yo Ichi Yamashita, shinji itoh, Norifumi Harimoto, Hirofumi Kawanaka, Ken Shirabe, Yoshihiko Maehara

    Surgery Today   45 ( 8 )   979 - 985   2015.8

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    DOI: 10.1007/s00595-014-0999-9

  • Surgical results for recurrent hepatocellular carcinoma after curative hepatectomy Repeat hepatectomy versus salvage living donor liver transplantation Reviewed

    Yo Ichi Yamashita, Yoshihiro Yoshida, Takeshi Kurihara, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Hideaki Uchiyama, Ken Shirabe, Yoshihiko Maehara

    Liver Transplantation   21 ( 7 )   961 - 968   2015.7

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    DOI: 10.1002/lt.24111

  • Impact of platelets and serotonin on liver regeneration after living donor hepatectomy Reviewed

    Tomoharu Yoshizumi, shinji itoh, D. Imai, Toru Ikegami, M. Ninomiya, T. Iguchi, Norifumi Harimoto, K. Takeishi, Y. Kimura, H. Uchiyama, Yuji Soejima, Tetsuo Ikeda, H. Kawanaka, K. Shirabe, Yoshihiko Maehara

    Transplantation Proceedings   47 ( 3 )   683 - 685   2015.4

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    DOI: 10.1016/j.transproceed.2014.11.050

  • Triple therapy using direct-acting agents for recurrent hepatitis C after liver transplantation A single-center experience Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Norifumi Harimoto, shinji itoh, K. Takeishi, H. Uchiyama, H. Kawanaka, Y. I. Yamashita, E. Tsujita, Noboru Harada, Eiji Oki, Hiroshi Saeki, Y. Kimura, K. Shirabe, Yoshihiko Maehara

    Transplantation Proceedings   47 ( 3 )   730 - 732   2015.4

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    DOI: 10.1016/j.transproceed.2014.10.058

  • Right paraduodenal hernia successfully treated with laparoscopic surgery Reviewed

    Takahiro Tomino, shinji itoh, Daisuke Yoshida, Takahiro Nishida, Hirofumi Kawanaka, Tetsuo Ikeda, Shunji Kohnoe, Ken Shirabe, Yoshihiko Maehara

    Asian journal of endoscopic surgery   8 ( 1 )   87 - 90   2015.2

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    DOI: 10.1111/ases.12139

  • BiClamp-Fracture Method in Pure Laparoscopic Hepatectomy Verifying its Efficacy Irrespective of Liver Stiffness Reviewed

    Hideaki Uchiyama, Kazutoyo Morita, shinji itoh, Kenji Takenaka, Yoshihiko Maehara

    Surgical Laparoscopy, Endoscopy and Percutaneous Techniques   25 ( 4 )   e113 - e116   2015.1

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    DOI: 10.1097/SLE.0000000000000172

  • Prognostic impact of Des-γ-carboxyl prothrombin in living-donor liver transplantation for recurrent hepatocellular carcinoma Reviewed

    47 ( 3 )   703 - 704   2015.1

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    Background Although the Milan criteria are widely accepted for liver transplantation (LT) in patients for hepatocellular carcinoma (HCC), they have not been fully evaluated for salvage LT in patients with recurrent HCC. We have previously reported outcomes of living-donor LT (LDLT) for HCC and identified 2 risk factors affecting recurrence-free survival (RFS): tumor size >5 cm and des-γ-carboxyl prothrombin (DCP) concentration >300 mAU/mL (Kyushu University criteria). This study was designed to clarify risk factors for tumor recurrence after LDLT in patients with recurrent HCC. Methods Outcomes in 114 patients who underwent LDLT for recurrent HCC were analyzed retrospectively. RFS rates after LDLT were calculated, and risk factors for tumor recurrence were identified. Results The 1-, 3-, and 5-year RFS rates after LDLT were 90.6%, 80.4%, and 78.8%, respectively. Univariate analysis showed that tumor recurrence was associated with alpha-fetoprotein concentration ≥300 ng/mL, DCP concentration ≥300 mAU/mL, tumor number ≥4, tumor size ≥5 cm, transarterial chemotherapy before LDLT, duration of last treatment of HCC to LDLT <3 months, bilobar distribution, exceeding Milan criteria, exceeding Kyushu University criteria, poor differentiation, and histologic vascular invasion. Multivariate analysis showed that DCP ≥300 mAU/mL (P =.03) and duration from last treatment to LDLT <3 months (P =.01) were independent predictors of RFS. Conclusions DCP concentration and time between last treatment and LDLT are prognostic of RFS in patients undergoing LDLT for HCC.

    DOI: 10.1016/j.transproceed.2014.09.178

  • Predictors of intrahepatic multiple recurrences after curative hepatectomy for hepatocellular carcinoma Reviewed

    Kazuki Takeishi, Takashi Maeda, Eiji Tsujita, Yo Ichi Yamashita, Noboru Harada, shinji itoh, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, Ken Shirabe, Yoshihiko Maehara

    Anticancer Research   35 ( 5 )   3061 - 3066   2015.1

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  • Outcomes after laparoscopic hepatectomy in the semi-prone position for hepatocellular carcinoma located in segment 6,7, or 8 Reviewed

    Norifumi Harimoto, Tetsuo Ikeda, Kazuki Takeishi, shinji itoh, Yo Ichi Yamashita, Toru Ikegami, Tomoharu Yoshizumi, Hirofumi Kawanaka, Ken Shirabe, Yoshihiko Maehara

    Anticancer Research   35 ( 7 )   4167 - 4170   2015.1

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  • Long-term outcome of living-donor liver transplantation for combined hepatocellular-cholangiocarcinoma Reviewed

    shinji itoh, Toru Ikegami, Tomoharu Yoshizumi, Huanlin Wang, Kazuki Takeishi, Norifumi Harimoto, Yo Ichi Yamashita, Hirofumi Kawanaka, Shinichi Aishima, Ken Shirabe, Yoshihiko Maehara

    Anticancer Research   35 ( 4 )   2475 - 2476   2015.1

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  • Laparoscopic Splenectomy with Technical Standardization and Selection Criteria for Standard or Hand-Assisted Approach in 390 Patients with Liver Cirrhosis and Portal Hypertension Reviewed

    Hirofumi Kawanaka, Tomohiko Akahoshi, Nao Kinjo, Norifumi Harimoto, shinji itoh, Norifumi Tsutsumi, Yoshihiro Matsumoto, Tomoharu Yoshizumi, Ken Shirabe, Yoshihiko Maehara

    Journal of the American College of Surgeons   221 ( 2 )   354 - 366   2015.1

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    DOI: 10.1016/j.jamcollsurg.2015.04.011

  • Correlation between portal vein anatomy and bile duct variation in 407 living liver donors Reviewed

    K. Takeishi, K. Shirabe, Y. Yoshida, Y. Tsutsui, T. Kurihara, K. Kimura, shinji itoh, Norifumi Harimoto, Y. I. Yamashita, Toru Ikegami, Tomoharu Yoshizumi, Akihiro Nishie, Yoshihiko Maehara

    American Journal of Transplantation   15 ( 1 )   155 - 160   2015.1

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    DOI: 10.1111/ajt.12965

  • Transdisciplinary Approach for Sarcopenia. Clinical significance of sarcopenia in the patients with chronic liver disease Reviewed

    Ken Shirabe, Norifumi Harimoto, Toru Ikegami, Tomoharu Yoshizumi, shinji itoh, Kazuki Takeishi, Takeo Toshima, Kohichi Kimura, Yoshihiro Matsumoto, Yuki Bekki, Daisuke Imai, Yoichi Yamashita, Hirofumi Kawanaka, Yoshihiko Maehara

    Clinical calcium   24 ( 10 )   1493 - 1499   2014.10

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  • Characteristic risk factors in cirrhotic patients for posthepatectomy complications Comparison with noncirrhotic patients Reviewed

    shinji itoh, Hideaki Uchiyama, Hirofumi Kawanaka, Takahiro Higashi, Akinori Egashira, Daihiko Eguchi, Toshiro Okuyama, Masahiro Tateishi, Daisuke Korenaga, Kenji Takenaka

    American Surgeon   80 ( 2 )   166 - 170   2014.2

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  • Effect of body composition on outcomes after hepatic resection for hepatocellular carcinoma Reviewed

    shinji itoh, Ken Shirabe, Yoshihiro Matsumoto, Shohei Yoshiya, Jun Muto, Norifumi Harimoto, Yo Ichi Yamashita, Toru Ikegami, Tomoharu Yoshizumi, Akihiro Nishie, Yoshihiko Maehara

    Annals of Surgical Oncology   21 ( 9 )   3063 - 3068   2014.1

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    DOI: 10.1245/s10434-014-3686-6

  • [Experience of 2013 Japan Exchange Fellow of the Japan Surgical Society and the American College of Surgeons]. Reviewed

    shinji itoh

    Nihon Geka Gakkai zasshi   115 ( 2 )   113 - 115   2014.1

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  • Tape-guided pure laparoscopic hepatectomy for laterally located tumors A technique to yield an appropriate tumor-free surgical margin and to make parenchymal transection easier Reviewed

    Hideaki Uchiyama, Kazutoyo Morita, shinji itoh, Kenji Takenaka

    Journal of the American College of Surgeons   219 ( 3 )   2014.1

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    DOI: 10.1016/j.jamcollsurg.2014.03.059

  • Small upper midline incision for living donor hemi-liver graft procurement in adults Reviewed

    Toru Ikegami, Ken Shirabe, Yo Ichi Yamashita, Tomoharu Yoshizumi, Norifumi Harimoto, Kazuki Takeishi, Eiji Tsujita, shinji itoh, Yoshihiko Maehara

    Journal of the American College of Surgeons   219 ( 3 )   2014.1

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    DOI: 10.1016/j.jamcollsurg.2014.04.021

  • Preemptive thoracic drainage to eradicate postoperative pulmonary complications after living donor liver transplantation Reviewed

    Daisuke Imai, Toru Ikegami, Takeo Toshima, Tomoharu Yoshizumi, Yo Ichi Yamashita, Mizuki Ninomiya, Norifumi Harimoto, shinji itoh, Hideaki Uchiyama, Ken Shirabe, Yoshihiko Maehara

    Journal of the American College of Surgeons   219 ( 6 )   1134 - 1142.e2   2014.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jamcollsurg.2014.09.006

  • Optimizing risk stratification in portal vein thrombosis after splenectomy and its primary prophylaxis with antithrombin III concentrates and danaparoid sodium in liver cirrhosis with portal hypertension Reviewed

    Hirofumi Kawanaka, Tomohiko Akahoshi, shinji itoh, Tomohiro Iguchi, Norifumi Harimoto, Hideaki Uchiyama, Tomoharu Yoshizumi, Ken Shirabe, Kenji Takenaka, Yoshihiko Maehara

    Journal of the American College of Surgeons   219 ( 5 )   865 - 874   2014.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jamcollsurg.2014.07.939

  • Long-term favorable surgical results of laparoscopic hepatic resection for hepatocellular carcinoma in patients with cirrhosis A single-center experience over a 10-year periods Reviewed

    Yo Ichi Yamashita, Tetsuo Ikeda, Takeshi Kurihara, Yoshihiro Yoshida, Kazuki Takeishi, shinji itoh, Norifumi Harimoto, Hirofumi Kawanaka, Ken Shirabe, Yoshihiko Maehara

    Journal of the American College of Surgeons   219 ( 6 )   1117 - 1123   2014.1

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    DOI: 10.1016/j.jamcollsurg.2014.09.003

  • Outcomes of emergency surgery for acute abdomen in dialysis patients Experience of a single community hospital Reviewed

    Takahiro Tomino, Hideaki Uchiyama, shinji itoh, Takahiro Higashi, Ai Edagawa, Akinori Egashira, Daihiko Eguchi, Hirofumi Kawanaka, Toshiroh Okuyama, Masahiro Tateishi, Daisuke Korenaga, Kenji Takenaka

    Surgery Today   44 ( 4 )   690 - 695   2014

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    DOI: 10.1007/s00595-013-0673-7

  • Reduced-dose telaprevir-based triple antiviral therapy for recurrent hepatitis C after living donor liver transplantation Reviewed

    Toru Ikegami, Tomoharu Yoshizumi, Masaki Kato, Satomi Yamamoto, Takasuke Fukuhara, Yoshiharu Matsuura, Shota Nakamura, shinji itoh, Ken Shirabe, Yoshihiko Maehara

    Transplantation   98 ( 9 )   994 - 999   2014

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    DOI: 10.1097/TP.0000000000000166

  • Pure laparoscopic partial hepatectomy using a newly developed vessel sealing device, BiClamp Reviewed

    Hideaki Uchiyama, shinji itoh, Takahiro Higashi, Daisuke Korenaga, Kenji Takenaka

    Surgical Laparoscopy, Endoscopy and Percutaneous Techniques   23 ( 3 )   2013.6

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    DOI: 10.1097/SLE.0b013e3182806535

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Presentations

  • 当院におけるロボット支援肝切除術の短期成績

    伊藤心二、吉屋匠平、戸島剛男、泉 琢磨、伊勢田憲史、筒井由梨子、二宮瑞樹、吉住朋晴

    第36回日本内視鏡外科学会総会  2023.12 

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    Event date: 2023.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • 当院における腹腔鏡下ドナー肝切除

    伊藤心二、内田康幸、福田篤久、戸島剛男、松浦俊治、吉住朋晴

    2023.12 

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    Event date: 2023.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • 肝細胞癌治療における肝切除の役割

    伊藤心二、吉屋匠平、吉住朋晴

    JDDW2023(第21回日本消化器外科学会大会)  2023.11 

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    Event date: 2023.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:神戸市   Country:Japan  

  • 予後向上を目指した進行肝細胞癌に対する薬物療法下での外科治療介入のインパクト Invited

    伊藤心二、利田賢哉、戸島剛男、吉屋匠平、泉 琢磨、伊勢田憲史、筒井由梨子、二宮瑞樹、吉住朋晴

    第61回日本癌治療学会学術集会  2023.10 

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    Event date: 2023.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • 進行肝細胞癌に対する先行薬物治療後の外科治療のインパクト

    伊藤心二、長尾吉泰、吉屋匠平、冨野高広、小斉侑希子、筒井由梨子、利田賢哉、中山湧貴、原田 昇、吉住朋晴

    第78回日本消化器外科学会総会  2023.7 

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    Event date: 2023.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:函館市   Country:Japan  

  • 局所進行肝細胞癌に対する薬物療法後の肝切除の意義 Invited

    伊藤心二、萱島寛人、森田和豊、長尾吉泰、栗原 健、吉屋匠平、冨野高広、小斉侑希子、利田賢哉、中山湧貴、原田 昇、吉住朋晴

    第123回日本外科学会定期学術集会  2023.4 

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    Event date: 2023.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 第109回日本消化器病学会総会

    伊藤心二、吉屋匠平、吉住朋晴

    第109回日本消化器病学会総会  2023.4 

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    Event date: 2023.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:長崎市   Country:Japan  

  • 肝細胞癌に対する腹腔鏡手術のインパクト

    伊藤心二、森田和豊、長尾吉泰、栗原 健、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第35回日本内視鏡外科学会総会  2022.12 

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    Event date: 2022.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋市   Country:Japan  

  • Intermediate stage肝細胞癌に対する肝切除の意義 Invited

    伊藤心二、森田和豊、萱島寛人、長尾吉泰、吉屋匠平、栗原 健、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第84回日本臨床外科学会総会  2022.11 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡市   Country:Japan  

  • 進行肝細胞癌における外科治療の意義 Invited

    伊藤心二、森田和豊、萱島寛人、長尾吉泰、吉屋匠平、栗原 健、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第84回日本臨床外科学会総会  2022.11 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡市   Country:Japan  

  • Intermediate stage肝細胞癌における外科治療の意義

    伊藤心二、原田 昇、吉住朋晴

    第20回日本消化器外科学会大会(JDDW2022)  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡市   Country:Japan  

  • 更なる予後向上を目指した進行肝細胞癌に対する集学的治療における外科治療の役割 Invited

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、吉住朋晴

    第60回日本癌治療学会学術集会  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:神戸市   Country:Japan  

  • Multidisciplinary treatment in HCC: Impact of surgical intervention after systemic therapy

    Shinji Itoh, Katsuya Toshida, Takahiro Tomiyama, Yukiko Kosai, Takahiro Tomino, Takeshi Kurihara, Yoshihiro Nagao, Kazutoyo Morita, Noboru Harada, Tomoharu Yoshizumi

    2022.7 

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    Event date: 2022.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌における集学的治療の一環と しての外科治療の意義

    伊藤心二、吉住朋晴

    第58回日本肝臓学会総会  2022.6 

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    Event date: 2022.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • Multidisciplinary treatment in HCC: Impact of surgery after multi-molecular target agent

    Shinji Itoh, Katsuya Toshida, Takahiro Tomiyama, Akinari Morinaga, Yukiko Kosai, Takahiro Tomino, Takeshi Kurihara, Yoshihiro Nagao, Kazutoyo Morita, Noboru Harada, Tomoharu Yoshizumi

    The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery  2022.6 

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    Event date: 2022.6

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 進行肝細胞癌に対する集学的治療における外科治療の意義

    伊藤心二、森 正樹、吉住朋晴

    第108回日本消化器病学会総会  2022.4 

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    Event date: 2022.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝細胞癌に対する生体肝移植における腫瘍内類洞様血管構造の意義 Invited

    伊藤心二、原田 昇、戸島剛男、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、森 正樹、吉住朋晴

    第83回日本臨床外科学会総会  2021.11 

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    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 原発性肝癌における癌代謝を反映するPET-CTと腫瘍免疫との関係

    伊藤心二、吉住朋晴、森 正樹

    第25回日本肝臓学会大会  2021.11 

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    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝胆膵悪性腫瘍の治療と最近の話題 Invited

    伊藤心二、沖 英次、森 正樹、吉住朋晴

    第59回日本癌治療学会  2021.10 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 肝細胞癌におけるレンバチニブ投与におけるフェロトーシスの役割

    伊藤心二、吉住朋晴、伊勢田憲史、原田 昇、森 正樹

    第80回日本癌学会学術総会  2021.9 

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    Event date: 2021.9

    Language:Japanese  

    Country:Japan  

  • Future perspectives of multidisciplinary treatment in HCC: Association with immune microenvironment

    2021.7 

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    Event date: 2021.7

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 進行肝細胞癌に対する薬物療法と外科治療を中心とした集学的治療

    伊藤心二、吉住朋晴、伊勢田憲史、利田賢哉、冨山貴央、森永哲成、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第57回日本肝癌研究会  2021.7 

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    Event date: 2021.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝悪性疾患における肝移植医療の適応拡大に向けた展望

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第39回日本肝移植学会  2021.6 

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    Event date: 2021.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌集学的治療における層別化治療にむけた展開

    伊藤心二、吉住朋晴、森 正樹

    第57回日本肝臓学会総会  2021.6 

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    Event date: 2021.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌に対するストレス応答蛋白Nrf2と腫瘍免疫,がん代謝との関連

    伊藤心二、吉住朋晴、森 正樹

    第107回日本消化器病学会総会  2021.4 

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    Event date: 2021.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 進行肝細胞癌に対する分子標的治療における手術療法の役割

    伊藤心二、吉住朋晴、栗原 健、島垣智成、王 歓林、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第121回日本外科学会定期学術集会  2021.4 

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    Event date: 2021.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌における微小環境下での腫瘍免疫とがん代謝の意義

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、下川雅弘、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第23回日本肝がん分子標的治療研究会  2021.1 

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    Event date: 2021.1

    Language:Japanese  

    Country:Japan  

  • 九州大学における「肝移植の醍醐味」 Invited

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、湯川恭平、小斉侑希子、井口詔一、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第38回日本肝移植学会  2020.12 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:紙面発表   Country:Japan  

  • 障害肝に対する残肝を考慮したICG蛍光イメージングによる腹腔鏡下肝切除

    伊藤心二、吉住朋晴、栗原 健、王 歓林、島垣智成、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第56回日本肝癌研究会  2020.12 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • DAA治療後の肝細胞癌に対する肝切除の意義

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第75回日本消化器外科学会総会  2020.12 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝胆膵悪性腫瘍における宿主および腫瘍免疫の意義とストレス応答の役割 Invited

    伊藤心二

    第31回日本消化器癌発生学会  2020.11 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  • 原発性肝癌における腫瘍免疫と癌代謝との関係

    伊藤心二、吉住朋晴、湯川恭平、伊勢田憲史、冨山貴央、森永哲成、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第31回日本消化器癌発生学会  2020.11 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝細胞癌における免疫回避調節因子CMTM6の意義

    伊藤心二、吉住朋晴、森 正樹

    2020.11 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝細胞癌における腫瘍免疫の意義と腫瘍内血管構築との関係

    伊藤心二、吉住朋晴、森 正樹

    第56回日本肝臓学会学術集会  2020.8 

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    Event date: 2020.8

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝臓外科における腹腔鏡下系統的肝切除の役割

    伊藤心二、吉住朋晴、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第120回日本外科学会定期学術集会  2020.8 

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    Event date: 2020.8

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝細胞癌(5cm以下、単発)における肝部分切除術と亜区域切除術の選択に関する検討

    伊藤心二、吉住朋晴 、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第81回日本臨床外科学会学術集会  2019.11 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:高知市   Country:Japan  

  • 肝細胞癌に対する腫瘍免疫と腫瘍内血管構築との関係

    伊藤心二、湯川恭平、伊勢田憲史、冨山貴央、森永哲成、小斉侑希子、井口詔一、 吉屋匠平、武石一樹、戸島剛男、原田 昇、池上 徹、吉住朋晴、森 正樹

    第30回日本消化器癌発生学会  2019.11 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • 肝移植外科医へのリクルート Invited

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、湯川恭平、小斉侑希子、井口詔一、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第55回日本移植学会総会  2019.10 

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    Event date: 2019.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:広島市   Country:Japan  

  • 肝臓外科領域におけるフレイルの意義

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第74回日本消化器外科学会総会  2019.7 

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    Event date: 2019.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • Recent treatment strategies for HCC -non-surgical treatment, resection and transplantation-

    Itoh S, Yoshizumi T, Imai D, Yoshiya S, Takeishi K, Harada N, Ikegami T, Mori M

    The 31st Meeting of Japanese Society of Hepato-Biliary-Pancreatic Sugery  2019.6 

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    Event date: 2019.6

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝臓外科における原発性肝癌に対する骨格筋量と免疫栄養指数の意義-サルコペニア判定基準を用いた解析-

    伊藤心二、原田 昇、吉住朋晴

    第55回日本肝臓学会学術集会  2019.5 

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    Event date: 2019.5 - 2020.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝移植周術期における呼吸器合併症対策

    伊藤心二、今井大祐、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二、吉住朋晴

    第31回日本外科感染症学会総会学術集会  2018.11 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌に対する外科治療成績向上のための戦略

    伊藤心二、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二、吉住朋晴

    第80回日本臨床外科学会学術集会  2018.11 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝細胞癌における腫瘍免疫を反映する新たなバイオマーカーの探求

    伊藤心二、吉住朋晴、前原喜彦

    第54回日本肝臓学会学術集会  2018.6 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市   Country:Japan  

  • 肝細胞癌に対する九大基準による生体肝移植の適応拡大

    伊藤心二、吉住朋晴、別城悠樹、間野洋平、本村貴志、戸島剛男、原田 昇、池上 徹、副島雄二、前原喜彦

    第36回日本肝移植研究会  2018.5 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝細胞癌における末梢血液分画比を用いた腫瘍免疫に関する新たなバイオマーカー

    伊藤心二

    第22回日本がん分子標的治療学会学術集会  2018.5 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝細胞癌に対する腫瘍免疫と微小環境をターゲットとした新規治療法の探求

    伊藤心二、吉住朋晴 、前原喜彦

    第104回日本消化器病学会総会  2018.4 

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    Event date: 2018.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 周術期における肝切除合併症回避のための治療戦略

    伊藤心二、吉住朋晴、播本憲史、大平将史、本村貴志、間野洋平、戸島剛男、原田 昇、池上 徹、副島雄二、池田哲夫、前原喜彦

    第79回日本臨床外科学会総会  2017.11 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • Lymphocyte-to-monocyte ratio is associated with PD-L1 expression on tumor progression in hepatocellular carcinoma

    Itoh S, Yoshizumi T, Shimokawa M, Mano Y, Motomura T, Toshima T, Harada N, Harimoto N, Ikegami T, Soejima Y, Maehara Y

    2017.11 

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    Event date: 2017.11

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • Relationship between skeletal muscle mass assessed by computed tomography and muscle strength in patients with liver disease. International conference

    Itoh S, Yoshizumi T, Nagatsu A, Motomura T, Harada N, Harimoto N, Ikegami T, Soejima Y, Ikeda T, Kamishima T, Maehara Y

    40th World Congress of the International College of Surgeons  2016.10 

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    Event date: 2016.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • Surgical treatment of hepatocellular carcinoma with macroscopic portal venous tumor thrombus

    Itoh S, Yoshizumi T, Harimoto N, Kimura K, Okabe H, Harada N, Ikegami T, Uchiyama H, Ikeda T, Maehara Y

    2016.7 

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    Event date: 2016.7

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • Phase I study of sorafenib in combination with uracil-tegafur in patients with unresectable advanced hepatocellular carcinoma in Japan International conference

    Shinji Itoh, Ken Shirabe, Koichi Kimura, Hironao Okabe, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Tomoharu Yoshizumi, Tetsuo Ikeda, Yoshihiko Maehara

    ESMO Asia 2015 Congress  2015.12 

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    Event date: 2015.12

    Language:English  

    Country:Singapore  

  • EOB-MRIを用いた新たな肝予備能評価の意義

    伊藤 心二

    第101回日本消化器病学会総会  2015.4 

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    Event date: 2015.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:仙台市   Country:Japan  

  • 肝細胞癌におけるMRI所見と癌微小環境との関連についての検討

    伊藤心二、冨野高広、利田賢哉 、伊勢田憲史、吉屋匠平、戸島剛男、小田義直、吉住朋晴

    第82回日本癌学会学術集会  2023.9 

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    Event date: 2023.9

    Language:Japanese  

    Venue:横浜市   Country:Japan  

  • 肝内胆管癌における高齢者に対する肝切除の治療成績

    伊藤心二、吉屋匠平、冨野高広、利田賢哉、原田 昇、吉住朋晴

    第59回日本胆道学会学術集会  2023.9 

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    Event date: 2023.9

    Language:Japanese  

    Venue:札幌市   Country:Japan  

  • 肝細胞癌に対する免疫複合療法と外科治療のコンビネーション

    伊藤心二、利田賢哉、長尾吉泰、吉屋匠平、冨野高広、下川雅弘、小斉侑希子、筒井由梨子、中山湧貴、原田 昇、吉住朋晴

    第59回日本肝癌研究会  2023.7 

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    Event date: 2023.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市   Country:Japan  

  • Comparison of background characteristics of patients receiving lenvatinib vs atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma International conference

    Shinji Itoh, Masafumi Ikeda, Daisuke Onozuka, Ryosuke Tateishi, Tatsuya Yamashita, Takuji Okusaka, Naoya Kato, Junji Furuse, Masatoshi Kudo

    APPLE2023  2023.7 

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    Event date: 2023.7

    Language:Japanese  

    Country:Korea, Republic of  

  • 肝細胞癌に対する肝切除術における微小脈管侵襲の意義

    伊藤心二、長尾吉泰、吉屋匠平、冨野高広、下川雅弘、小斉侑希子、筒井由梨子、利田賢哉、中山湧貴、原田 昇、吉住朋晴

    第59回日本肝癌研究会  2023.7 

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    Event date: 2023.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:大阪市   Country:Japan  

  • 当院における生体肝移植術後胆管合併症の現状

    伊藤心二、原田 昇、戸島剛男、長尾吉泰、吉屋匠平、冨野高広、下川雅弘、小斉侑希子、筒井由梨子、利田賢哉、中山湧貴、吉住朋晴

    第41回日本肝移植学会学術集会  2023.6 

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    Event date: 2023.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 基礎と臨床から紐解くこれからの進行肝細胞癌治療 Invited

    伊藤心二

    第27回日本がん分子標的治療学会学術集会  2024.6 

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    Event date: 2023.6

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:佐賀市   Country:Japan  

  • 複合免疫療法時代における肝細胞癌の集学的治療戦略 Invited

    伊藤心二

    第48回日本外科系連合学会学術集会  2023.6 

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    Event date: 2023.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:横浜市   Country:Japan  

  • 薬物療法と外科の協働による肝細胞癌の治療戦略

    伊藤心二、原田 昇、吉住朋晴

    第59回日本肝臓学会総会  2023.6 

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    Event date: 2023.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:奈良市   Country:Japan  

  • 当院でのロボット支援下肝切除術の治療成績

    伊藤心二、吉屋匠平、萱島寛人、長尾吉泰、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第15回日本ロボット外科学会学術集会  2023.2 

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    Event date: 2023.2

    Language:Japanese  

    Country:Japan  

  • 切除不能肝細胞癌における薬物療法に関する 前向き観察研究(PRISM 試験)

    伊藤心二、池田公史、建石良介、山下竜也、奥坂拓志、加藤直也、古瀬純司、工藤正俊

    第27回日本肝がん分子標的治療研究会  2023.1 

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    Event date: 2023.1

    Language:Japanese  

    Country:Japan  

  • 当院におけるロボット支援下肝切除術の導入

    伊藤心二、森田和豊、長尾吉泰、栗原 健、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第35回日本内視鏡外科学会総会  2022.12 

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    Event date: 2022.12

    Language:Japanese  

    Venue:名古屋市   Country:Japan  

  • 当院でのロボット支援下肝切除術の導入

    伊藤心二、吉屋匠平、萱島寛人、長尾吉泰、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第16回肝臓内視鏡外科研究会  2022.11 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡市   Country:Japan  

  • 肝細胞癌に対する集学的治療と低侵襲手術

    伊藤心二、森田和豊、長尾吉泰、栗原 健、冨野高広、小斉侑希子、原田 昇、吉住朋晴

    第32回九州内視鏡・ロボット外科手術研究会  2022.9 

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    Event date: 2022.9

    Language:Japanese  

    Venue:大分市   Country:Japan  

  • 生体肝移植ドナーにおける新たな手術手技

    伊藤心二、原田 昇、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、戸島剛男、森田和豊、吉住朋晴

    第40回日本肝移植学会学術集会  2022.7 

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    Event date: 2022.7

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 肝細胞癌に対する薬物療法における骨格筋量が予後へ及ぼす影響

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、吉住朋晴

    第24回日本肝がん分子標的治療研究会  2022.6 

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    Event date: 2022.6

    Language:Japanese  

    Venue:軽井沢市   Country:Japan  

  • 個別化治療を目指した肝細胞癌における微小環境のバイオマーカーの探求

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、吉住朋晴

    第24回日本肝がん分子標的治療研究会  2022.6 

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    Event date: 2022.6

    Language:Japanese  

    Venue:軽井沢市   Country:Japan  

  • 進行肝細胞癌に対する集学的治療における外科治療の意義

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、吉住朋晴

    第58回日本肝癌研究会  2022.5 

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    Event date: 2022.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 個別化治療を目指した肝細胞癌における微小環境のバイオマーカーの探求

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、森 正樹、吉住朋晴

    第122回日本外科学会定期学術集会  2022.4 

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    Event date: 2022.4

    Language:Japanese  

    Venue:熊本市   Country:Japan  

  • 膵頭十二指腸術後の膵液漏に対する超音波内視鏡下膵管ドレナージ

    伊藤心二、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、吉住朋晴

    第58回日本腹部救急医学会総会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝胆膵外科医における胆道癌へのゲノム医療への関わり

    伊藤心二、吉住朋晴、森 正樹

    第57回日本胆道学会学術集会  2021.10 

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    Event date: 2021.10

    Language:Japanese  

    Country:Japan  

  • 生体肝移植レシピエント手術における新たな手術手技- 肝動脈処理の工夫-

    伊藤心二、原田 昇、戸島剛男、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、森 正樹、吉住朋晴

    第57回日本移植学会  2021.9 

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    Event date: 2021.9

    Language:Japanese  

    Country:Japan  

  • 進行肝細胞癌に対する薬物療法における外科治療の役割

    伊藤心二、吉住朋晴、利田賢哉、冨山貴央、森永哲成、小斉侑希子、冨野高広、栗原 健、長尾吉泰、森田和豊、原田 昇、森 正樹

    第24回日本肝がん分子標的治療研究会  2021.8 

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    Event date: 2021.8

    Language:Japanese  

    Country:Japan  

  • 腫瘍内血管から見た肝細胞癌における新規概念:腫瘍内類洞様血管構造の意義

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第30回日本がん転移学会学術集会  2021.7 

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    Event date: 2021.7

    Language:Japanese  

    Country:Japan  

  • 肝細胞癌に対する腫瘍免疫に着目した個別化治療に向けた展開

    伊藤心二、吉住朋晴、伊勢田憲史、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第57回日本肝癌研究会  2021.7 

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    Event date: 2021.7

    Language:Japanese  

    Country:Japan  

  • Effect of indocyanine green fluorescence navigation in laparoscopic liver resection: a single center experience and propensity score matching study

    Shinji Itoh, Tomoharu Yoshizumi, Takeshi Kurihara, Tomonari Shimagaki, Huanlin Wang, Yoshihiro Nagao, Takeo Toshima, Noboru Harada, Masaki Mori

    2021.6 

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    Event date: 2021.6

    Language:English  

    Country:Japan  

  • 肝細胞癌における腫瘍微小環境下でのPD-L1調節因子CMTM6の生物学的意義

    伊藤心二、森 正樹

    第25回日本がん分子標的治療学会  2021.5 

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    Event date: 2021.5

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • Impact of frailty on short and long-term outcomes in patients after liver resection

    Shinji Itoh, Tomoharu Yoshizumi, Takeshi Kurihara, Shohei Yoshiya, Yoshihiro Nagao, Kazuki Takeishi, Takeo Toshima, Noboru Harada, Toru Ikegami, Masaki Mori

    2021.2 

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    Event date: 2021.2

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝臓外科領域におけるフレイルの意義 Invited

    伊藤心二、吉住朋晴、島垣智成、王 歓林、栗原 健、長尾吉泰、戸島剛男、原田 昇、森 正樹

    第82回日本臨床外科学会学術集会  2020.10 

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    Event date: 2020.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝細胞癌おける8-OHdGとDNA修復酵素OGG1発現の意義

    伊藤心二、湯川恭平、吉住朋晴、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、孝橋賢一、小田義直、森 正樹

    第72回日本酸化ストレス学会学術集会  2020.10 

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    Event date: 2020.10

    Language:Japanese  

    Venue:紙面開催   Country:Japan  

  • 原発性肝癌に対する肝切除術後早期の骨格筋量変化の意義

    伊藤心二、吉住朋晴、森 正樹

    第56回日本肝臓学会学術集会  2020.8 

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    Event date: 2020.8

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:Web   Country:Japan  

  • 肝細胞癌に対する腫瘍免疫の意義

    伊藤心二、吉住朋晴、湯川恭平、伊勢田憲史、冨山貴央、森永哲成、小斉侑希子、井口詔一、吉屋匠平、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第22回日本肝がん分子標的治療研究会  2020.1 

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    Event date: 2020.1

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 障害肝併存肝細胞癌に対する傾向スコアを用いた開腹vs腹腔鏡下肝切除術の検討

    伊藤心二、吉住朋晴、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第32回日本内視鏡外科学会総会  2019.12 

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    Event date: 2019.12

    Language:Japanese  

    Country:Japan  

  • 生体肝移植症例における肝線維化マーカーM2BPGiの意義

    伊藤心二、吉住朋晴、今井大祐、吉屋匠平、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第55回日本移植学会総会  2019.10 

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    Event date: 2019.10

    Language:Japanese  

    Venue:広島市   Country:Japan  

  • 肝内胆管癌における術前栄養・炎症マーカーの意義に関する検討

    伊藤心二、吉住朋晴、今井大祐、吉屋匠平、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第55回日本胆道学会学術集会  2019.10 

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    Event date: 2019.10 - 2020.10

    Language:Japanese  

    Venue:名古屋市   Country:Japan  

  • 障害肝に対する残肝を考慮した腹腔鏡下肝切除

    伊藤心二、吉住朋晴、冨山貴央、伊勢田憲史、森永哲成、井口詔一、湯川恭平、小斉侑希子、吉屋匠平、長尾吉泰、武石一樹、戸島剛男、原田 昇、池上 徹、森 正樹

    第14回肝癌ナビゲーション研究会  2019.9 

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    Event date: 2019.9

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 膵癌における免疫栄養指数の意義ー多施設における解析ー

    伊藤心二、辻田英司、吉住朋晴、福澤謙吾、杉町圭史、二宮瑞樹、前田貴司、梶山 潔、足立英輔、内山秀昭、宇都宮徹、原田 昇、池上 徹、副島雄二、森 正樹

    第50回日本膵臓学会大会  2019.7 

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    Event date: 2019.7

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 障害肝での肝細胞癌に対する傾向スコアを用いた開腹vs腹腔鏡下肝切除の比較検討

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第55回日本肝癌研究会  2019.7 

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    Event date: 2019.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌における肝部分切除術と亜区域切除術の選択に関する検討

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、間野洋平、長尾吉泰、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第119回日本外科学会 定期学術集会  2019.4 

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    Event date: 2019.4

    Language:Japanese  

    Country:Japan  

  • 腹腔鏡下肝切除の定型化に向けた取り組み

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、間野洋平、長尾吉泰、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第11回福岡県医学会総会  2019.2 

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    Event date: 2019.2

    Language:Japanese  

    Venue:福岡市   Country:Japan  

  • 巨大肝腫瘍に対する我々の肝切除術

    伊藤心二、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、湯川恭平、小斉侑希子、井口詔一、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二、森 正樹

    第40回九州肝臓外科研究会  2019.1 

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    Event date: 2019.1

    Language:Japanese  

    Venue:福岡市   Country:Japan  

  • 左半腹臥位を用いた肝右葉前上、後区域領域における腹腔鏡下肝切除術

    伊藤心二、吉住朋晴、池田哲夫、川﨑淳司、島垣智成、坂田一仁、下川雅弘、吉田佳弘、長津明久、本村貴志、原田 昇、播本憲史、池上 徹、副島雄二、前原喜彦

    第10回肝臓内視鏡下外科研究会  2016.11 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 腹腔鏡下肝切除の定型化に向けた取り組み

    伊藤心二、吉住朋晴、栗原 健、吉屋匠平、間野洋平、武石一樹、原田 昇、池上 徹、副島雄二

    第12回肝臓内視鏡外科研究会  2018.11 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 非B非C肝細胞癌に対する肝切除成績およびHBc抗体との関連

    伊藤心二、吉住朋晴、間野洋平、本村貴志、戸島剛男、原田 昇、播本憲史、池上 徹、副島雄二、前原喜彦

    第15回日本消化器外科学会大会  2017.10 

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    Event date: 2017.10

    Language:Japanese  

    Venue:福岡市   Country:Japan  

  • Impact of lymphocyte-to-monocyte ratioon progression in hepatocellular carcinoma associated with PD-L1 expression

    Itoh S, Yoshizumi T, Shimokawa M, Mano Y, Motomura T, Toshima T, Harada N, Harimoto N, Ikegami T, Soejima Y, Maehara Y

    2017.9 

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    Event date: 2017.9

    Language:Japanese  

    Country:Japan  

  • トルバプタンを用いた肝切除術後における腹水発症予防の治療戦略

    伊藤心二、吉住朋晴、間野洋平、本村貴志、戸島剛男、原田 昇、播本憲史、池上 徹、副島雄二、前原喜彦

    第24回日本門脈圧亢進症学会総会  2017.9 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • 肝予備能が低下した肝硬変併存深部肝細胞癌に対する手術手技- Split Enucleation -

    伊藤心二、吉住朋晴、池上 徹、長津明久、本村貴志、間野洋平、原田 昇、播本憲史、副島雄二、池田哲夫、前原喜彦

    第71回手術手技研究会  2017.5 

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    Event date: 2017.5

    Language:Japanese  

    Venue:名古屋市   Country:Japan  

  • The technical evolution for laparoscopic hepatectomy

    2017.4 

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    Event date: 2017.4

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 肝細胞癌における代謝性疾患とB型肝炎既感染との関連に関する研究

    伊藤心二、吉住朋晴、副島雄二、池上 徹、播本憲史、原田 昇、本村貴志、王 歓林、長津明久、吉田佳弘、下川雅弘、坂田一仁、島垣智成、川崎淳司、池田哲夫、前原喜彦

    第103回日本消化器病学会総会  2017.4 

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    Event date: 2017.4

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 腹腔鏡下肝切除の進歩と高齢者肝細胞癌患者への適応拡大

    伊藤心二、吉住朋晴、池田哲夫、王 歓林、長津明久、本村貴志、原田 昇、播本憲史、池上 徹、副島雄二、前原喜彦

    第29回日本内視鏡外科学会総会  2016.12 

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    Event date: 2016.12

    Language:Japanese  

    Venue:横浜市   Country:Japan  

  • 門脈内腫瘍栓を伴う肝細胞癌に対する外科治療を中心とした治療戦略

    伊藤心二、吉住朋晴、副島雄二、池上 徹、播本憲史、原田 昇、本村貴志、王 歓林、長津明久、吉田佳弘、下川雅弘、坂田一仁、島垣智成、川﨑淳司、池田哲夫、前原喜彦

    第78回日本臨床外科学会総会  2016.11 

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    Event date: 2016.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  • ABO血液型不適合生体肝移植の成績向上に向けた我々の戦略

    伊藤心二、吉住朋晴、副島雄二、池上 徹、播本憲史、原田 昇、本村貴志、王 歓林、長津明久、吉田佳弘、下川雅弘、坂田一仁、島垣智成、池田哲夫、前原喜彦

    第52回日本移植学会総会  2016.9 

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    Event date: 2016.9 - 2016.10

    Language:Japanese  

    Venue:東京   Country:Japan  

  • B型肝炎既往感染による肝細胞癌発癌・悪性度への影響に関する研究

    伊藤心二、吉住朋晴、副島雄二、池上 徹、播本憲史、原田 昇、本村貴志、王 歓林、長津明久、吉田佳弘、下川雅弘、坂田一仁、島垣智成、川崎淳司、池田哲夫、前原喜彦

    第27回日本消化器癌発生学会総会  2016.9 

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    Event date: 2016.9

    Language:Japanese  

    Venue:鹿児島市   Country:Japan  

  • 生体肝移植レシピエントにおける新しい肝門部処理〜New hilar dissection〜

    伊藤心二、吉住朋晴、池上 徹、副島雄二、播本憲史、原田 昇、本村貴志、長津明久、王 歓林、前原喜彦

    第34回日本肝移植研究会  2016.7 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:旭川市   Country:Japan  

  • Surgical treatment of hepatocellular carcinoma with macroscopic portal venous tumor thrombus

    Itoh S, Yoshizumi T, Harimoto N, Kimura K, Okabe H,Harada N, Ikegami T, Uchiyama H, Ikeda T, Maehara Y

    2016.6 

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    Event date: 2016.6

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  • 門脈内腫瘍栓を有する進行肝癌に対する外科切除を中心とした治療成績

    伊藤心二、調 憲 、播本憲史、下川雅弘、坂田一仁、吉田佳弘、冨野高広、今井大祐、別城悠樹、王 歓林、木村光一、岡部弘尚、池上 徹、内山秀昭、吉住朋晴、池田哲夫、前原喜彦

    第102回日本消化器病学会総会  2016.4 

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    Event date: 2016.4

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 門脈内腫瘍栓を有する進行肝癌に対する外科治療成績と分子機序に基づいた新しい治療戦略

    伊藤心二、調 憲 、播本憲史、下川雅弘、坂田一仁、吉田佳弘、冨野高広、今井大祐、別城悠樹、王 歓林、木村光一、岡部弘尚池上 徹、内山秀昭、吉住朋晴、池田哲夫、前原喜彦

    第116回日本外科学会定期学術集会  2016.4 

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    Event date: 2016.4

    Language:Japanese  

    Venue:大阪市   Country:Japan  

  • 肝細胞癌に対する腹腔鏡下肝切除術の治療成績

    伊藤心二、池田哲夫、坂田一仁、下川雅弘、吉田佳弘、今井大祐、別城悠樹、木村光一、岡部弘尚、播本憲史、池上 徹、内山秀昭、吉住朋晴、調 憲、前原喜彦

    第28回日本内視鏡外科学会総会  2015.12 

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    Event date: 2015.12

    Language:Japanese  

    Venue:大阪市   Country:Japan  

  • 当教室における血液型不適合生体肝移植の長期成績

    伊藤 心二

    第51回日本移植学会総会  2015.10 

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    Event date: 2015.10

    Language:Japanese  

    Venue:熊本市   Country:Japan  

  • 術前肝細胞癌の診断で術後混合型肝癌と診断された症例に対する生体肝移植の成績

    伊藤心二、調  憲、栗原 健、吉田佳宏、今井大祐、別城悠樹、王 歓林、木村光一、松本佳大、武石一樹、播本憲史、山下洋市、池上 徹、吉住朋晴、川中博文、池田哲夫、前原喜彦

    第23回日本消化器関連学会週間(第13回日本消化器外科学会大会)  2015.10 

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    Event date: 2015.10

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 肝細胞癌に対する生体肝移植術における体内組成評価(骨格筋/内脂肪比)の意義に関する研究

    伊藤 心二

    第70回日本消化器外科学会総会  2015.7 

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    Event date: 2015.7

    Language:Japanese  

    Venue:浜松市   Country:Japan  

  • 腹腔鏡下肝切除術の進歩

    伊藤 心二

    第105回日本消化器学会九州支部例会  2015.6 

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    Event date: 2015.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:長崎市   Country:Japan  

  • 肝細胞癌に対する生体肝移植術におけるBody compositionの意義に関する研究

    伊藤 心二

    第27回日本肝胆膵外科学会総会  2015.6 

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    Event date: 2015.6

    Language:Japanese  

    Venue:東京   Country:Japan  

  • 生体肝移植レシピエントの肝十二指腸靭帯剥離における結紮を用いない肝動脈処理による動脈解離予防効果と剥離手技の定型化

    伊藤 心二

    第69回手術手技研究会  2015.5 

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    Event date: 2015.5

    Language:Japanese  

    Venue:高崎市   Country:Japan  

  • 生体肝移植レシピエントの肝十二指腸靭帯剥離における結紮を用いない肝動脈処理による動脈解離予防効果と剥離手技の定型化

    伊藤 心二

    第33回日本肝移植研究会  2015.5 

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    Event date: 2015.5

    Language:Japanese  

    Country:Japan  

  • EOB-MRIおよび3D-CT volumetryを用いた新たな肝予備能評価

    伊藤 心二

    第115回日本外科学会定期学術集会  2015.4 

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    Event date: 2015.4

    Language:Japanese  

    Venue:名古屋市   Country:Japan  

  • Impact of the Inflammatory Marker Soluble CD163 for Patients with Hepatocellular Carcinoma following Hepatic Resection

    2014.11 

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    Language:Japanese  

    Country:Japan  

  • 大腸癌肝転移に対する腹腔鏡下肝切除術の有用性

    伊藤 心二

    第27回日本内視鏡外科学会総会  2014.10 

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    Language:Japanese  

    Venue:盛岡   Country:Japan  

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MISC

  • ロボット支援下肝切除の現状 Reviewed

    伊藤心二、吉住朋晴

    肝臓   2023.12

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Professional Memberships

  • 九州内視鏡・ロボット外科手術研究会

  • 九州外科学会

  • 日本肝癌研究会

  • 日本肝がん分子標的治療研究会

  • 日本バイオセラピィ学会

  • 日本肝移植学会

  • 日本門脈圧亢進症学会

  • 日本酸化ストレス学会

  • 日本腹部救急医学会

  • 日本外科感染症学会

  • 日本消化器癌発生学会

  • 日本臨床外科学会

  • 日本がん転移学会

  • 日本がん分子標的治療学会

  • 日本内視鏡外科学会

  • 日本癌学会

  • 日本癌治療学会

  • 日本消化器病学会

  • 日本移植学会

  • 日本膵臓学会

  • 日本胆道学会

  • 日本肝臓学会

  • 日本肝胆膵外科学会

  • 日本消化器外科学会

  • 日本外科学会

  • American College of Surgeons

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Committee Memberships

  • Councilor   Domestic

    2023.11 - Present   

  • Councilor   Domestic

    2023.9 - Present   

  • Councilor   Domestic

    2023.9 - Present   

  • Steering committee member   Domestic

    2022.7 - Present   

  • 日本肝臓学会   治験支援委員会委員   Domestic

    2022.7 - Present   

  • Councilor   Domestic

    2022.5 - Present   

  • Councilor   Domestic

    2022.4 - Present   

  • Councilor   Domestic

    2022.3 - Present   

  • Councilor   Domestic

    2022.1 - Present   

  • Councilor   Domestic

    2021.1 - Present   

  • 日本肝がん分子標的治療研究会   世話人   Domestic

    2021.1 - Present   

  • Councilor   Domestic

    2020.6 - Present   

  • Councilor   Domestic

    2019.6 - Present   

  • Councilor   Domestic

    2019.1 - Present   

  • 日本肝臓学会   西部支部評議員   Domestic

    2017.11 - Present   

  • 日本消化器病学会   九州支部評議員   Domestic

    2017.6 - Present   

  • Steering committee member   Domestic

    2013.11 - Present   

  • 日本消化器癌発生学会   財務委員   Domestic

    2013.11 - Present   

  • Councilor   Domestic

    2011.11 - Present   

  • Councilor   Domestic

    2009.6 - Present   

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Academic Activities

  • Screening of academic papers

    Role(s): Peer review

    2023

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:58

    Number of peer-reviewed articles in Japanese journals:2

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:9

  • Screening of academic papers

    Role(s): Peer review

    2022

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:61

    Number of peer-reviewed articles in Japanese journals:1

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2021

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:49

    Number of peer-reviewed articles in Japanese journals:1

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2020

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:41

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2019

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:18

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2018

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:9

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

  • Screening of academic papers

    Role(s): Peer review

    2017

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    Type:Peer review 

    Number of peer-reviewed articles in foreign language journals:3

    Number of peer-reviewed articles in Japanese journals:0

    Proceedings of International Conference Number of peer-reviewed papers:0

    Proceedings of domestic conference Number of peer-reviewed papers:0

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Research Projects

  • IMPACT試験

    2023.7

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    Authorship:Coinvestigator(s) 

  • LEOPARD-Neo試験

    2023.6

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    Authorship:Coinvestigator(s) 

  • GAIA試験

    2023.4

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    Authorship:Coinvestigator(s) 

  • 肝癌微小環境における薬物療法耐性機序解明と新規治療法の開発

    Grant number:23K08133  2023 - 2025

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • PRISM-Bio試験

    2022.7

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    Authorship:Coinvestigator(s) 

  • COSMOS試験

    2021.5

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    Authorship:Coinvestigator(s) 

    肝細胞癌患者の血液循環腫瘍DNAのゲノム・エピゲノム統合解析を行う

  • REPLACEMENT試験

    2020.12

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    Authorship:Coinvestigator(s) 

    BCLC-B(up to 7)の肝細胞癌に対するアテゾリズマブ+ベバシズマブ療法の有効性と安全性を検討する多施設共同第2相試験

  • PRISM試験

    2020.6

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    Authorship:Coinvestigator(s) 

    切除不能肝細胞癌に対する薬物療法によるシークエンシャル治療の実態を明らかにする。切除不能肝細胞癌に対する全身薬物療法を開始する症例を前向きに登録し、各治療ラインにおけるそれぞれの治療レジメンの治療効果を検討する。

  • HAMRET試験

    2020.2

    KSCC(日本) 

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    Authorship:Coinvestigator(s) 

    切除不能肝細胞癌に対する薬物療法によるシークエンシャル治療の実態を明らかにする。切除不能肝細胞癌に対する全身薬物療法(ソラフェニブ、レンバチニブ)を開始する症例を前向きに登録し、一次治療を含めた各治療ラインにおけるそれぞれの治療レジメンの治療効果を検討する。

  • 肝癌における新規細胞死フェロトーシス機序解明と革新的治療法への開発

    Grant number:19K09198  2019 - 2021

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • ストレス応答性転写因子による代謝リプログラミングを標的とした肝癌への革新的治療

    Grant number:16K10576  2016 - 2018

    日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Scientific research funding

  • 治療抵抗性肝細胞癌おけるマイクロRNAの機能解析と新規治療への展開

    Grant number:26893191  2014 - 2015

    日本学術振興会  科学研究費助成事業  研究活動スタート支援

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    Authorship:Principal investigator  Grant type:Scientific research funding

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Other educational activity and Special note

  • 2023  Class Teacher 

  • 2022  Class Teacher 

  • 2021  Class Teacher 

  • 2020  Class Teacher 

  • 2019  Class Teacher 

  • 2018  Class Teacher 

  • 2017  Class Teacher 

  • 2016  Class Teacher 

  • 2015  Class Teacher 

  • 2014  Class Teacher 

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Outline of Social Contribution and International Cooperation activities

  • 日本消化器外科学会評議員として消化器外科の治療向上に寄与している。
    日本癌学会評議員として癌の制圧への研究の向上に寄与している。
    日本肝臓学会評議員・支部評議員として肝疾患の治療向上に寄与している。
    日本肝臓学会治験支援委員会委員として治験支援を行っている。
    日本消化器病学会評議員・支部評議員として消化器病疾患の治療向上に寄与している。
    日本肝胆膵外科学会評議員として難治性肝胆膵癌に対する治療成績の向上に寄与している。
    日本臨床外科学会評議員として外科臨床における治療向上に寄与している。
    日本がん分子標的治療学会評議員として分子標的治療の向上に寄与している。
    日本消化器癌発生学会評議員として消化器癌進展のメカニズムの解明に寄与している。
    日本酸化ストレス学会代議員として酸化ストレス学の向上に寄与している。
    日本肝がん分子標的治療研究会世話人として肝細胞癌に対する治療向上に寄与している。
    日本癌治療学会代議員として癌治療の発展に寄与している。
    日本移植学会代議員として移植医療の向上に寄与している。
    福岡県社会福祉審議会障がい者福祉専門分科会審査部会委員として活動を行っている。

Social Activities

  • 平成29年度福岡県医師会肝臓がん検診講習会福岡地区講師

    福岡県医師会  2017.11

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    Audience: General, Scientific, Company, Civic organization, Governmental agency

    Type:Seminar, workshop

Specialized clinical area

  • Biology / Medicine, Dentistry and Pharmacy / Surgical Clinical Medicine / Liver/Biliary/Pancreatic Surgery

  • Biology / Medicine, Dentistry and Pharmacy / Surgical Clinical Medicine / General Surgery

Clinician qualification

  • Preceptor

    日本膵臓学会

  • Preceptor

    日本胆道学会

  • Certifying physician

    日本移植学会

  • 高度技能指導医

    日本肝胆膵外科学会

  • Specialist

    The Japan Society of Hepatology(JSH)

  • Preceptor

    The Japan Society of Hepatology(JSH)

  • Specialist

    The Japanese Society of Gastroenterology(JSGE)

  • Certifying physician

    The Japan Society for Endoscopic Surgery(JSES)

  • Preceptor

    The Japanese Society of Gastroenterology(JSGE)

  • Specialist

    The Japanese Society of Gastroenterological Surgery

  • Preceptor

    The Japanese Society of Gastroenterological Surgery

  • Certifying physician

    Japan Surgical Society(JSS)

  • Specialist

    Japan Surgical Society(JSS)

  • Preceptor

    Japan Surgical Society(JSS)

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Year of medical license acquisition

  • 2000

Notable Clinical Activities

  • 難治性肝胆膵悪性腫瘍に対する集学的治療(特に手術・薬物療法)に従事 生体肝移植の手術・術前術後管理に従事