Updated on 2025/06/09

Information

 

写真a

 
YONEKAWA AKIKO
 
Organization
Kyushu University Hospital Center for the Study of Global Infection Assistant Professor
School of Medicine Department of Medicine(Concurrent)
Title
Assistant Professor
Homepage
External link

Research Areas

  • Life Science / Infectious disease medicine

Degree

  • M.D., Ph.D.

Research History

  • Kyushu University Kyushu University Hospital Center for the Study of Global Infection  Assistant Professor 

    2020.4 - Present

Research Interests・Research Keywords

  • Research theme: Infectious disease

    Keyword: Infection and immunity

    Research period: 2021.7 - 2024.7

Papers

  • Parotitis caused by Mycobacteroides abscessus subspecies abscessus

    Yonekawa A., Miyake N., Minami J., Murakami D., Fukano H., Hoshino Y., Kubo K., Chong Y., Akashi K., Shimono N.

    Auris Nasus Larynx   49 ( 3 )   525 - 528   2022.6   ISSN:03858146

     More details

    Language:English   Publisher:Auris Nasus Larynx  

    Rapidly growing mycobacteria rarely causes parotitis. We report a rare case of Mycobacteroides abscessus subspecies abscessus (MAB) parotitis in a previously healthy 26-year-old woman. She presented to the previous hospital with a swelling over the right parotid region, and a computed tomography scan revealed multiple abscesses in the swollen parotid gland. Histopathology showed granulomatous inflammation with acid-fast bacilli; however, a subsequent culture failed to isolate mycobacterium. Despite repeated antibiotic therapy and multiple surgical interventions including partial incision and drainage of the abscesses, the parotitis did not resolved. At six months after presentation, she was referred to our institute. We performed enlarged resection of the necrotic tissue and abscesses, and the sample cultivated after homogenization was positive for mycobacterium. The isolate was finally identified as MAB. She underwent long-term postoperative antibiotic therapy for MAB, with a favorable outcome. To the best of our knowledge, this is the first case of MAB parotitis where the subspecies has been identified. MAB is much more intractable than the other subspecies. We highlight the importance of the correct identification of MAB, which leads to the appropriate treatment.

    DOI: 10.1016/j.anl.2020.11.005

    Scopus

    PubMed

  • Clinical Significance of COVID-19 and Diabetes: In the Pandemic Situation of SARS-CoV-2 Variants including Omicron (B.1.1.529)

    Yonekawa, A; Shimono, N

    BIOLOGY-BASEL   11 ( 3 )   2022.3   ISSN:2079-7737 eISSN:2079-7737

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    Language:English   Publisher:Biology  

    The coronavirus disease 2019 (COVID-19) global pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains uncontrolled, with the spread of emerging variants. According to accumulating evidence, diabetes is one of the leading risk factors for a severe COVID-19 clinical course, depending on the glycemic state before admission and during COVID-19 hospitalization. Multiple factors are thought to be responsible, including an altered immune response, coexisting comorbidity, and disruption of the renin-angiotensin system through the virus–host interaction. However, the precise underlying mechanisms remain under investigation. Alternatively, the focus is currently on the diabetogenic and ketosis-prone potential of SARS-CoV-2 itself, even for probable triggers of stress and steroid-induced hyperglycemia in COVID-19. In this article, we present a comprehensive review of the recent literature on the clinical and experimental findings associated with diabetes and COVID-19, and we discuss their bidirectional relationship, i.e., the risk for an adverse prognosis and the deleterious effects on glycometabolism. Accurate as-sessments of the incidence of new-onset diabetes induced by COVID-19 and its pathogenicity are still unknown, especially in the context of the circulation of SARS-CoV-2 variants, such as Omicron (B.1.1.529), which is a major challenge for the future.

    DOI: 10.3390/biology11030400

    Web of Science

    Scopus

    PubMed

MISC

Professional Memberships

  • The Japanese Society of Internal Medicine

  • The Japanese Association for Infectious Diseases

Outline of Social Contribution and International Cooperation activities

  • 周辺地域の医療機関と連携して、主に院内感染対策の情報交換を行っている。

Notable Clinical Activities

  • 血液・腫瘍・心血管内科および免疫・膠原病・感染症内科において、免疫不全患者を中心とした特殊病態下の感染症診療や、当該病棟の感染予防対策に従事している。 さらに、グローバル感染症センターのスタッフとして、全診療科の血液培養陽性症例への介入、感染症コンサルテーションへの対応、ならびに抗菌薬適正使用支援等を行っている。