記述言語：日本語  

COVID-19に関連した経済不安が大学生の健康に及ぼす影響‐大学実態調査より‐

記述言語：英語   掲載種別：研究論文（学術雑誌）  

In 1952, the Japanese Society for Hygiene had once passed a resolution at its 22nd symposium on population control, recommending the suppression of population growth based on the idea of cultivating a healthier population in the area of eugenics. Over half a century has now passed since this recommendation; Japan is witnessing an aging of the population (it is estimated that over 65-year-olds made up 27.7% of the population in 2017) and a decline in the birth rate (total fertility rate 1.43 births per woman in 2017) at a rate that is unparalleled in the world; Japan is faced with a "super-aging" society with low birth rate. In 2017, the Society passed a resolution to encourage all scientists to engage in academic researches to address the issue of the declining birth rate that Japan is currently facing. In this commentary, the Society hereby declares that the entire text of the 1952 proposal is revoked and the ideas relating to eugenics is rejected. Since the Society has set up a working group on the issue in 2016, there have been three symposiums, and working group committee members began publishing a series of articles in the Society's Japanese language journal. This commentary primarily provides an overview of the findings from the published articles, which will form the scientific basis for the Society's declaration. The areas we covered here included the following: (1) improving the social and work environment to balance between the personal and professional life; (2) proactive education on reproductive health; (3) children's health begins with nutritional management in women of reproductive age; (4) workplace environment and occupational health; (5) workplace measures to counter the declining birth rate; (6) research into the effect of environmental chemicals on sexual maturity, reproductive function, and the children of next generation; and (7) comprehensive research into the relationship among contemporary society, parental stress, and healthy child-rearing. Based on the seven topics, we will set out a declaration to address Japan's aging society with low birth rate.

DOI： 10.1186/s12199-019-0768-x

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

学術研究からの少子化対策－非正規雇用と結婚、妊娠出産、育児

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Background: Menstrual problems can significantly impact daily and work life. In reaction to a shrinking population, the Japanese government is encouraging more women to participate in the labor force. Actual success in achieving this aim, however, is limited. Specifically, participation in the workforce by women during their reproductive years is impacted by their health, which involves not only work conditions, but also traditional family circumstances. Therefore, it is important to further assess and gather more information about the health status of women who work during their reproductive years in Japan. Specifically, women's health can be represented by menstruation status, which is a pivotal indicator. In this study, we assessed the association between short rest periods in work intervals and menstruation and other health status indicators among female workers in Japan.
Methods: Study participants were recruited from the alumnae of a university, which provided a uniform educational level. All 9864 female alumnae were asked to join the survey and 1630 (17%) accepted. The final sample of study participants (n = 505) were aged 23-43 years, had maintained the same job status for at least 1 year, and were not shift workers, had no maternal status, and did not lack any related information. The participants were divided into two groups according to interval time, with 11 h between end of work and resumption of daily work as a benchmark. This interval time was based on EU regulations and the goal set by the government of Japan. Health outcomes included: menstrual cycle, dysmenorrhoea symptoms, anxiety regarding health, and satisfaction in terms of health. Multiple logistic regression analyses were conducted to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for health indexes in association with interval time by adjusting for confounding variables that included both psychosocial and biological factors.
Results: We compared the health status of women in the workforce with and without a sufficient interval time of 11 h/day. Workers who had a short interval time had a significantly higher prevalence of anxiety about health and dissatisfaction with their health. For menstruation status, only abnormal menstruation cycles were observed more often among workers in the short interval group than those of the long interval group. However, this association disappeared when biological confounding factors were adjusted in a multivariable regression model. Dysmenorrhea symptoms did not show a statistically significant association with short interval time.
Conclusions: This study found a significant association between a short interval time of less than 11 h/day and subjective health indicators and the menstrual health status of women in the workforce. Menstrual health was more affected by biological factors than social psychological factors. A long work time and short interval time could increase worker anxiety and dissatisfaction and may deteriorate the menstrual cycle.

DOI： 10.1186/s13030-017-0112-x

記述言語：その他  

Female non-regular workers in Japan: their current status and health.

DOI： 10.2486/indhealth.2016-0105

記述言語：英語   掲載種別：研究論文（学術雑誌）  

This study aimed to quantify the contributions of the factors that have influenced changes in income-related health inequalities. We used data from a nationally representative sample of Japanese men and women aged 20-59 years who participated in eight repeated cross-sectional surveys between 1986 and 2007. A concentration index (Cl) was used to measure income-related inequalities in self-rated health (SRH) and decomposed into contributing factors. We then examined temporal changes in CIs and their contributing factors. Results showed that income-related inequalities in SRH, unfavourable to low-income groups, persisted throughout the study period. Despite widening income inequalities, inequalities in SRH narrowed during the period of economic stagnation since the late 1990s because of the profound deterioration in SRH among middle- to high-income groups. Decomposition analysis showed that income itself and unemployment or economic inactivity were the most important contributors to inequalities in SRH for both sexes at almost all time points. However, from 1986 to 2007, the relative contribution of income to these inequalities decreased from 78% to 14% in men and from 85% to 38% in women. By contrast, the relative contribution of unemployment or economic inactivity increased from 18% to 77% in men and from 10% to 31% in women. Our results suggest that a reduction in avoidable health inequalities could be achieved by reducing the influence of unemployment or economic inactivity on health. (C) 2012 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.socscimed.2012.11.042

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Objective: Self-rated health (SRH) reflects lifestyle habits, chronic disease, and psychosocial conditions. The aim of this study was to examine the relationship between transitions in SRH and health indicators among Japanese white-collar workers. Methods: Three-year medical examination data from an occupational field was used. The distribution of data related to SRH, lifestyle habits, treatment of chronic disease, laboratory data abnormalities, job stress, and sickness absences were compared using ridit analysis, and the odds ratios and 95% confidence intervals were calculated using the first year of observation as a reference. Results: During the observation period, the proportion of workers with poor SRH, self-rated lifestyle habits, sleep, dietary habits, and body mass index increased. Particularly, high job stress (heavy job burden and low job control) and few sickness absences were strongly related to poor SRH. Conclusions: Unfavorable lifestyles and work-related conditions worsened as SRH declined among workers. The results suggest that health indicators related to SRH are different according to the population. Tracking changes in SRH using indices related to SRH is useful for evaluating the health status in a target group.

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Background Precarious employment is one of the social determinants of health. In 2010, 34.4% of Japanese workers fell into this employment category. The purpose of our study was to assess whether the use of annual health check-ups varied by worker contract type. Methods Using 2007 nationally representative survey data, we compared the annual health check-up compliance of permanently employed full-time workers versus that of precariously employed workers (hourly, dispatched, and fixed-term workers). Results Dispatched workers and hourly workers received health check-ups less often compared with permanent workers. Hourly young male workers received health check-ups five times less frequently than permanent workers. The percentage of workers who consulted a physician after receiving advice to do so did not differ by employment types, except in older men. Conclusions In Japan, workers with precarious employment, most notably hourly and dispatched workers, had a lower rate of health check-ups compared with full-time workers in permanent positions. Am. J. Ind. Med. 55:884892, 2012. (C) 2012 Wiley Periodicals, Inc.

DOI： 10.1002/ajim.22090

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Effect of unequal employment status on workers' health: Results from a Japanese national survey
This study assesses the possibility of a period effect on Japanese workers' health and its association with historical changes in the work environment. We used multi-year national cross-sectional surveys, the Comprehensive Survey of Living Conditions for 2001, 2004, and 2007, and estimated the period effect on the health of employed workers aged 18-65 years. The prevalence of ill-health indicators (poor self-rated health status, subjective symptoms, and the number of respondents receiving consultations from medical doctors and other health professionals) significantly increased during this period. Deteriorating trends in these health indicators persisted after adjusting for age and cohort effects and for individual factors such as employment, marital, and child-rearing status. Furthermore, after adjusting for income level as an individual factor, deteriorating trends remained for the poor self-rated health status of male employees, subjective symptoms of female employees, and receiving medical consultations for both genders. The health status of employed workers in Japan deteriorated, especially from 2004 to 2007, regardless of age and cohort effects. After taking individual socio-economic factors and the effects of the recession on society into consideration, we hypothesized a posteriori that the increase in precarious non-regular work may be the main factor underlying this period effect and may be the cause of the deterioration in workers' health. (C) 2012 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.socscimed.2011.11.039

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.socscimed.2012.03.032

記述言語：英語   掲載種別：研究論文（学術雑誌）  

This study assesses the possibility of a period effect on Japanese workers' health and its association with historical changes in the work environment. We used multi-year national cross-sectional surveys, the Comprehensive Survey of Living Conditions for 2001, 2004, and 2007, and estimated the period effect on the health of employed workers aged 18-65 years. The prevalence of ill-health indicators (poor self-rated health status, subjective symptoms, and the number of respondents receiving consultations from medical doctors and other health professionals) significantly increased during this period. Deteriorating trends in these health indicators persisted after adjusting for age and cohort effects and for individual factors such as employment, marital, and child-rearing status. Furthermore, after adjusting for income level as an individual factor, deteriorating trends remained for the poor self-rated health status of male employees, subjective symptoms of female employees, and receiving medical consultations for both genders. The health status of employed workers in Japan deteriorated, especially from 2004 to 2007, regardless of age and cohort effects. After taking individual socio-economic factors and the effects of the recession on society into consideration, we hypothesized a posteriori that the increase in precarious non-regular work may be the main factor underlying this period effect and may be the cause of the deterioration in workers' health.

DOI： 10.1016/j.socscimed.2011.11.039

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Recent studies suggest that unstable employment contracts may affect the health of workers. Many Japanese workers working full time in ostensibly permanent positions actually operate within unstable and precarious employment conditions. We compared the health status of Japanese workers with precarious employment contracts with that of permanent workers using the 2007 Comprehensive Survey of Living Conditions of the People on Health and Welfare (n=205,994). We classified their employment status as 'permanent' vs. 'precarious' (part-time, dispatch, or contract/non-regular) and compared their health conditions. Among both sexes, precarious workers were more likely than permanent workers to have poor self-rated health or more subjective symptoms, with more workers in full-time employment suffering from serious psychological distress (SPD) and more female workers who smoke. Using logistic regression, we identified a positive association between precarious employment and SPD and current smoking among workers engaged in full-time employment after adjusting for age, marital status, and work-related conditions. This study demonstrates that precarious employment contracts are associated with poor self-rated health, psychological distress, and tobacco use, especially among people working full-time jobs. These results suggest that engagement in full-time work tinder unstable employment status impairs workers' health.

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Chronic kidney disease (CKD) is an important risk factor for cardiovascular disease. The metabolic risk factors obesity, hypertension, diabetes, and dyslipidemia are closely associated with renal dysfunction. As psychosocial stress affects these risk factors, here, we examined relationships between metabolic risk factors and renal function, and their association with job stress. The participants were 1,231 Japanese male office workers attending annual health examinations. The estimated glomerular filtration rate (eGFR) was determined using the equation recommended by the Japanese Society for Nephrology: eGFR (mL/min/1.73 m(2)) = 194x age(-0.287) x Cr-1.094. Job stress was measured using the Job Content Questionnaire based on the job demand-control model. The job strain index equaled the job demand scores divided by the job control scores. The participants were classified into four ordinal groups of job strain index, based on previous studies (i.e., <= 0.4 the lowest, 0.4-0.5 lower, 0.5-0.6 higher, or >= 0.6 the highest). A significant correlation was found between lowered eGFR and each of the metabolic risk factors waist circumference, systolic and diastolic blood pressure, and total cholesterol (p < 0.001). Furthermore, job stress had an interactive effect on the relationships between eGFR and systolic and diastolic blood pressure, and triglycerides, depending on the job strain index (highest vs. lowest) (p < 0.05). The highly stressed workers exhibited a close association of eGFR with metabolic risk factors like hypertension and dyslipidemia. Therefore, intensive management may be important for preventing the progression of renal dysfunction and cardiovascular complications in those experiencing stress.

DOI： 10.1620/tjem.226.101

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1136/bmjopen-2012-000958

記述言語：その他  

[Factors associated with working among female physicians in Japan].

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）  

A focus exclusively on waist circumference, the main component used in the diagnosis of metabolic syndrome (MetS), may lead to ignoring non-obese individuals with other MetS components, including high levels of blood pressure, fasting blood glucose, and triglycerides and low levels of high-density lipoprotein. This study investigated lifestyles and eating behaviors among non-obese individuals with components of MetS. Of the 918 Japanese male workers, 151 subjects (16.4%) had a waist circumference < 85 cm with more than one MetS component. This non-obese high-risk group for MetS gained weight in adulthood, consume alcohol, and engage in less leisure-time physical activity compared to 317 subjects (34.5%) with a waist circumference < 85 cm and without MetS components (p < 0.05). The remaining 450 subjects (49%) were obese with a waist circumference >= 85, including 93 men with MetS. A lack of leisure-time physical activity was associated with the non-obese high-risk group for MetS [odds ratio 1.59, 95% confidence interval 1.02 - 2.49] compared to the 317 non-obese men without MetS (reference group). Such a difference in physical activity was not found between the 450 obese subjects and the reference group. Instead, eating behaviors, such as eating rapidly, preference for fatty foods, and eating out for dinner, were significantly associated with MetS. Thus, men with smaller waist circumferences and any MetS component should be carefully monitored for physical activity to prevent further development of MetS, while men with larger waist circumferences including MetS need to be monitored for unfavorable eating behaviors.

DOI： 10.1620/tjem.223.269

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Background: In the past decade, the changing labor market seems to have rejected the traditional standards employment and has begun to support a variety of non-standard forms of work in their place. The purpose of our study was to compare the degree of job stress, sources of job stress, and association of high job stress with health among permanent and fixed-term workers.Methods: Our study subjects were 709 male workers aged 30 to 49 years in a suburb of Tokyo, Japan. In 2008, we conducted a cross-sectional study to compare job stress using an effort-reward imbalance (ERI) model questionnaire. Lifestyles, subjective symptoms, and body mass index were also observed from the 2008 health check-up data.Results: The rate of job stress of the high-risk group measured by ERI questionnaire was not different between permanent and fixed-term workers. However, the content of the ERI components differed. Permanent workers were distressed more by effort, overwork, or job demand, while fixed-term workers were distressed more by their job insecurity. Moreover, higher ERI was associated with existence of subjective symptoms (OR = 2.07, 95% CI: 1.42-3.03) and obesity (OR = 2.84, 95% CI:1.78-4.53) in fixed-term workers while this tendency was not found in permanent workers.Conclusions: Our study showed that workers with different employment types, permanent and fixed-term, have dissimilar sources of job stress even though their degree of job stress seems to be the same. High ERI was associated with existing subjective symptoms and obesity in fixed-term workers. Therefore, understanding different sources of job stress and their association with health among permanent and fixed-term workers should be considered to prevent further health problems. © 2010 Inoue et al
licensee BioMed Central Ltd.

DOI： 10.1186/1751-0759-4-16

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Background Recent studies on the association between the metabolic syndrome (MetS) and depression have reported conflicting findings. This 1-year cohort study aims to evaluate the association of MetS with the development of both depression and anxiety.
Methods The cohort comprised 956 Japanese male employees of an enterprise (mean age, 42.7 years; SD, 10.2 years). MetS was diagnosed according to the International Diabetes Federation criteria. The psychological conditions of depression and anxiety were assessed in 2 successive years by using the profile of mood states (POMS) questionnaire and by conducting clinical interviews as per the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). We evaluated the temporal and dose-response relationships between MetS and the development of depression and anxiety, controlling for potential confounding factors like age and lifestyle-related factors.
Results We identified a positive relationship between MetS at baseline and new-onset depression in the subsequent year (OR 2.14, 95% Cl 1.10-4.17). Of the five MetS components examined only waist circumference, was significantly related to new-onset depression (OR 2.08, 1.23-3.50). Trend analysis revealed a significant positive trend of association between the number of MetS components identified and new-onset depression (P(trend) < 0.01), but not between Mets and new-onset anxiety.
Conclusions Our results suggest that MetS is a predictive factor for the development of depression, and that waist circumference largely contributes to the association between MetS and depression. Copyright (C) 2009 John Wiley & Sons, Ltd.

DOI： 10.1002/dmrr.1041

記述言語：その他  

[Health status of precarious workers in "Toshikoshi Haken Mura (Dispatch Workers' New Year Village)"].

DOI： 10.1539/sangyoeisei.C9002

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Galanin-like peptide (GALP) is a newly discovered 60 amino acid peptide from the porcine hypothalamus. GALP has been shown to be expressed predominantly in the arcuate nucleus (ARC) of the rat hypothalamus, a region considered to be one of the most important feeding-regulating centers in the brain. GALP-containing neurons in the ARC express leptin receptors, but relationships between GALP and other feeding-regulating neurons have not yet been fully elucidated. Given that Orexin (OX)-containing neurons make synaptic inputs to the ARC, we thus examined the relationship between GALP and OX in the ARC by use of a dual immunostaining technique. OX-immunoreactive fibers appeared to be closely apposed to GALP-immunoreactive cell bodies and their processes. We also examined whether the OX receptor, OX(1)-R was expressed in the GALP-containing neurons. Immunoreactivity for both OX(1)-R and GALP was detectable in 9.6 % neurons (range 4.2-14.6%) in the ARC. These findings strongly suggest that GALP may participate in the regulation of feeding behavior under the influence of leptin and OX.

記述言語：英語   掲載種別：研究論文（学術雑誌）  

The distribution and ultrastructural localization of the orexin-1 receptor (OX(1)R) in the rat arcuate nucleus were studied using immunocytochemical techniques. OX(1)R-containing neurons were found throughout the nucleus, but were concentrated in its posterior region. Both OX(1)R-positive perikarya and dendrites were found to receive synapses from other unknown axon terminals. In addition, a small number of OX(1)R-positive axon terminals were observed. These OX(1)R-immunoreactive axon terminals were often found to make synapses on unidentified immunonegative dendritic processes. The present results indicate that orexin may act on food intake regulating neurons through both pre- and post-synaptic OX(1)R.

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Immunohistochemistry and Western blotting were used to determine the distribution of orexin receptors in the rat brain. Strong orexin receptor 1 (OX1R) immunoreactivity was detected in the hypothalamus including the arcuate, ventromedial, and tuberomammillary nuclei that are involved in feeding regulation. The neuropeptide Y- and proopiomelanocortin-containing neurons of the arcuate nucleus, which act to stimulate or to inhibit feeding, respectively, displayed intense OX1R immunoreactivity by double immunostaining. Western blotting analysis yielded a 50-kDa major band of OX1R.

記述言語：日本語  

Consultaion-liaison Service in University Hospitals

担当ページ：限界への挑戦―摂食障害の男性例   記述言語：日本語   著書種別：学術書

担当ページ：Chapter 6 : The Role of Glucocorticoids and Retinoic Acid in the Pituitary Endocrine Cell Differentiation.   記述言語：英語   著書種別：学術書

担当ページ：心身症を治す―消化性潰瘍   記述言語：日本語   著書種別：学術書

記述言語：日本語  

クルズス診療科（2）心療内科

記述言語：日本語  

この疾患をどう治す

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非正規研究者の健康状況に関する調査—非常勤講師アンケートからー

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労働者のメンタルヘルスの年次比較―国民生活基礎調査から―

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高学歴女性の雇用形態と健康―職種を含めた解析―

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非正規雇用の多様性と健康問題

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非正規雇用の多様性と健康問題―現場の声から―

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工学系大学の女性研究者の現状と産業保健上の課題

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非正規研究者の健康状況に関する調査―非常勤講師アンケートからー

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理工系単科大学における障害者支援のあり方 ―肢体不自由学生の事例より―

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単科大学における障害者支援―肢体不自由学生の事例を通して考える―

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「研究・教育界における不安定雇用 非常勤講師の生活と健康」

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非正規研究者の健康状況ー非常勤講師健康調査よりー

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理工系大学における障害学生支援 ―合理的配慮の実情と課題―

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大学における障害学生支援のあり方 ―合理的配慮をめぐる現状と課題―

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大学非正規教員の就労と健康－非常勤講師健康調査から―

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非正規雇用者の健康状態と職業特性

記述言語：日本語  

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大学非正規教員の就労と健康―非常勤講師健康調査から―

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大学非正規教員の健康ー非常勤講師健康調査より―

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工学系女性研究者の現状と非正規雇用

記述言語：日本語  

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若年労働者の雇用形態変化と心理的ストレスとの関連 －10年間のコホート研究から―.

記述言語：日本語  

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不安定就労世帯 健康と幸福度.

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運動の有能性に着目したサポートが運動教室中の身体活動量に及ぼす影響

記述言語：日本語  

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脊髄損傷を有する車椅子使用者の生活活動強度推定に関する予備検討

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非正規研究者の健康問題と就労－大学非常勤講師アンケートから－

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労働契約法改正と雇止め：大学非常勤講師を例として

記述言語：英語  

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Effects of electrical muscle stimulation on cognitive performance and cerebral perfusion.

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Mood changes induced by Electrical Muscle Stimulation and voluntary exercise

記述言語：英語  

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Sympathetic nervous system activity during electrical muscle stimulation and voluntary exercise

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Effects of electrical muscle stimulation on cognitive performance and cerebral perfusion.

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持続可能な地域包括ケアシステム構築に向けて ー担い手である中高年者ボランティアの特徴ー

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ランダムフォレストを⽤いた ⾞椅⼦利⽤者の活動強度の推定

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Does structure of the brain predict cognitive performance at rest and during exercise?

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Differential effects of electrical muscle stimulation and voluntary exercise on cognitive performance: role of sympathetic nervous system activation

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Effects of acute exercise on cognitive performance: an fMRI study

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Beneficial effects of acute exercise on cognitive performance via arousal-related brain network activation

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車椅子使用者を対象とした身体活動強度推定に関する心拍データの寄与度

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COVID-19と不安定雇用（3）：労働力調査による多様な就業・産業別休業者の動向

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COVID-19と不安定雇用（1）：労働力調査と米国雇用統計より―易解雇集団の特徴

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COVID-19と不安定雇用（2）：労働力調査と大学実態調査より―就労学生への影響

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COVID-19に関連した経済不安が大学生の健康に及ぼす影響‐大学実態調査より‐

記述言語：日本語  

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リアルタイム遠隔運動プログラムが高齢者の身体活動に与える効果

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COVID-19に関連した経済不安と大学生の健康 ―学生生活実態調査より―

記述言語：日本語  

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COVID-19に関連した経済不安が大学生の健康に及ぼす影響 −実態調査より−