Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(公社)日本口腔外科学会  

症例は74歳女性で、腎細胞癌および脳転移に対する薬物療法目的に入院となった。入院時に右側口底部の違和感を認めたため当科受診となり、画像所見で右側舌下腺腫瘍を認め、局所麻酔下に切開生検を行い、腎細胞癌の舌下腺転移と診断された。カボザンチニブによる薬物治療を開始したところ、治療開始から6ヵ月で原発巣、脳転移巣の著明な縮小に加え、舌下腺の転移病変もほぼ消失が得られた。その後も薬物療法は継続中で、治療開始後1年5ヵ月経過した現在も原発巣・転移巣ともに増大は認めていない。

Publisher：Journal of Oral and Maxillofacial Surgery Medicine and Pathology  

An osteoma is a benign tumor consisting of a proliferation of mature bone. The osteomas are categorized as per their origin into peripheral and central. Peripheral osteoma is a rare entity originating from the periosteum. Peripheral osteomas are found in areas, such as the paranasal sinuses and mandible, but rarely occur in the maxilla. Herein, we describe a case of giant peripheral osteoma that developed in the maxilla and then grew to such an extent that it became difficult for the patient to masticate. The patient was a 61-year-old woman who visited our hospital complaining of a painless mass on her palate that gradually increased in size starting from 15 years ago. A bone-like hard mass with a major axis of approximately 65 mm was found covering the entire palate. The tumor was pedunculated and the base was at the alveolar crest of the maxillary molars. The computed tomography findings showed a well-defined mass surrounded by cortical bone, with a mixture of internal cortical bone-like and cancellous or spongy bone-like parts. A biopsy was performed, and the diagnosis of osteoma was confirmed. Tumor resection was then performed. The size of the resected specimen was 67 × 58 × 29 mm. Histopathologically, it was classified as a cancellous osteoma and was finally diagnosed as peripheral osteoma. The patient was observed for 1 year following the operation and no recurrence was observed.

DOI： 10.1016/j.ajoms.2022.02.006

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Language：Japanese  

Language：Japanese   Presentation type：Oral presentation (general)