Kyushu University Academic Staff Educational and Research Activities Database
List of Presentations
Kenji Hamase Last modified date:2024.04.17

Professor / Department of Chemo-Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences


Presentations
1. Kenji HAMASE, Chiral amino acid analysis for drug discovery and diagnosis, 39th International annual meeting in pharmaceutical science, 2024.03.
2. Kenji HAMASE, Three/four dimensional chiral HPLC analysis of amino acids in mammals; Their origins, regulation systems and diagnostic values, 33rd International Symposium on Pharmaceutical and Biomedical Analysis, 2023.07.
3. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Tomonori KIMURA, Kenji HAMASE, Selective determination of D-amino acids in human plasma using a two-dimensional LC-MS/MS system toward early-diagnosis of chronic kidney disease, 33rd International Symposium on Pharmaceutical and Biomedical Analysis, 2023.07.
4. Yuri NAGATA, Takeyuki AKITA, Chiharu ISHII, Mai OYAIDE, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development of an enantioselective three-dimensional HPLC system for the simultaneous determination of aliphatic amino acids in human plasma and urine, 51st International Symposium on High- Performance Liquid Phase Separations and Related Techniques, 2023.06.
5. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Tomonori KIMURA, Kenji HAMASE, Screening of new diagnostic markers for chronic kidney disease focusing on chiral amino acids using a highly selective two-dimensional LC-MS/MS system, 51st International Symposium on High- Performance Liquid Phase Separations and Related Techniques, 2023.06.
6. Kenji HAMASE, Chiharu ISHII, Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Wolfgang LINDNER, Multi-dimensional HPLC concepts integrating highly efficient enantioselective columns for the analysis of chiral amino acids in complicated real-world samples, 51st International Symposium on High- Performance Liquid Phase Separations and Related Techniques, 2023.06.
7. Mai OYAIDE, Chiharu ISHII, Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Tomonori KIMURA, Kenji HAMASE, Development of a three-dimensional HPLC system for the determination of hydroxy amino acid enantiomers in the plasma of patients with renal disorder, 51st International Symposium on High- Performance Liquid Phase Separations and Related Techniques, 2023.06.
8. Aogu FURUSHO, Chiharu ISHII, Takeyuki AKITA, Hiroshi NARAOKA, Kenji HAMASE, Three dimensional HPLC determination of chiral amino acids in the Hayabusa2 return sample from Ryugu, 51st International Symposium on High- Performance Liquid Phase Separations and Related Techniques, 2023.06.
9. Mai OYAIDE, Chiharu ISHII, Aogu FURUSHO, Masashi MITA, Takeyuki AKITA, Tomomi IDE, Tomonori KIMURA, Kenji HAMASE, Three-dimensional HPLC determination of serine/threonine/allo-threonine enantiomers in the plasma of patients with chronic kidney disease, 日本薬学会第143年会次世代薬学アジアシンポジウム, 2023.03.
10. Kenji HAMASE, Multi-dimensional and enantioselective HPLC analysis of amino acids and related compounds - method development and application to real-world samples -, RSC Tokyo International Conference 2022, 2022.12.
11. Chiharu ISHII, Yukiko SHIMIZU, Takeyuki AKITA, Masashi MITA, Tadashi OKAMURA, Kenji HAMASE, Selective determination of D-amino acids in the rat plasma and urine using a two-dimensional LC-MS/MS system and their regulation by D-amino acid oxidase, 12th International symposium on drug analysis & 32nd International symposium on pharmaceutical and biomedical analysis, 2022.09.
12. Kenji HAMASE, Multi-dimensional HPLC analysis of chiral amino acids in complicated matrices including clinical, food and extraterrestrial samples, 12th International symposium on drug analysis & 32nd International symposium on pharmaceutical and biomedical analysis, 2022.09.
13. Kenji HAMASE, Multi-dimensional HPLC analysis of chiral amino acids in complicated matrices including clinical, food and extraterrestrial samples, 12th International symposium on drug analysis & 32nd International symposium on pharmaceutical and biomedical analysis, 2022.09.
14. Chiharu ISHII, Yukiko SHIMIZU, Takeyuki AKITA, Masashi MITA, Tadashi OKAMURA, Kenji HAMASE, Simultaneous determination of chiral amino acids in the plasma and brain of DAO deficient rats using a highly selective two-dimensional LC-MS/MS system, The 5th International conference of D-amino acid research, 2022.07.
15. Kenji HAMASE, Enantioselective analysis of amino acids and related compounds using multi-dimensional HPLC and its medical applications, The 5th International conference of D-amino acid research, 2022.07.
16. Hsin-Miao TSAI, Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Development of an enantioselective three-dimensional HPLC system for the determination of lactate, hydroxybutyrates and malate in human urine, 第29回クロマトグラフィーシンポジウム, 2022.06.
17. Siew Hwei YAP, Yi Xian ER, Soo Ching LEE, Cheng Siang LEE, Aogu FURUSHO, Chiharu ISHII, Nurul Syuhada ZULHAMI, Masashi MITA, Kenji HAMASE, Kok Hoong LEONG, Yvonne Ai Lian LIM, Reena RAJASURIAR , Plasma D-amino acids are associated with gut microbial diversity and specific bacterial taxa in people living with and without HIV, Asia-Pacific AIDS and Co-infections Conference, 2022.06.
18. Kenji HAMASE, Enantioselective analysis of amino acids and related compounds for biomarker screening using micro/narrowbore three-dimensional HPLC, Pacifichem 2021, 2021.12.
19. Chiharu ISHII, Yukiko SHIMIZU, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Tadashi OKAMURA, Kenji HAMASE, Determination of plasma D-amino acids in human and laboratory rodents with various D-amino acid oxidase activities using a two-dimensional HPLC-MS/MS system, Pacifichem 2021, 2021.12.
20. Hsin-Miao TSAI, Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Two-dimensional chiral HPLC analysis of lactate, hydroxybutyrates and malate in mammalian physiological fluids and food samples, クロマトグラフィー次世代技術セミナー2021, 2021.10.
21. Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Akira FUJII, Masanobu NAGANO, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Enantioselective determination of lactate in vinegars including Japanese traditional kurozu samples and the developmental changes during fermentation processes, クロマトグラフィー次世代技術セミナー2021, 2021.10.
22. Chiharu ISHII, Yukiko SHIMIZU, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Tadashi OKAMURA, Kenji HAMASE, Development of a two-dimensional LC-MS/MS system for the selective determination of intrinsic chiral amino acids and application to mammalian plasma, 31st International Symposium on Pharmaceutical and Biomedical Analysis, 2021.08.
23. Aogu FURUSHO, Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Kenji HAMASE, Development of a highly sensitive and selective three-dimensional HPLC system for the determination of chiral amino acids in carbonaceous meteorites, 31st International Symposium on Pharmaceutical and Biomedical Analysis, 2021.08.
24. Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Akira FUJII, Masanobu NAGANO, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Enantioselective determination of lactate in various food samples including Japanese traditional amber rice vinegar and the developmental changes during fermentation processes, 31st International Symposium on Pharmaceutical and Biomedical Analysis, 2021.08.
25. Masataka KAJIWARA, Takeyuki AKITA, Chiharu ISHII, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development of a high-performance three-dimensional HPLC system for the determination of Ser and Asp enantiomers in human physiological fluids, 31st International Symposium on Pharmaceutical and Biomedical Analysis, 2021.08.
26. Hsin-Miao TSAI, Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Enantioselective determination of lactate, hydroxybutyrates and malate in mammalian plasma using a two-dimensional chiral HPLC system, 31st International Symposium on Pharmaceutical and Biomedical Analysis, 2021.08.
27. Hsin-Miao TSAI, Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Development of a two-dimensional chiral HPLC system for the simultaneous determination of lactate, hydroxybutyrates and malate, 第28回クロマトグラフィーシンポジウム , 2021.06.
28. Chin-Ling HSIEH, Chiharu ISHII, Takeyuki AKITA, Akira FUJII, Masanobu NAGANO, Masashi MITA, Jen-Ai LEE, Kenji HAMASE, Enantioselective analysis of lactate in Japanese traditional amber rice vinegar and the developmental changes during fermentation processes, 第28回クロマトグラフィーシンポジウム, 2021.06.
29. Kenji HAMASE, Multi-dimensional HPLC analysis of D-amino acids and related compounds and its clinical applications, 第43回日本分子生物学会年会, 2020.12.
30. Kenji HAMASE, Chiral analysis of amino acids and related compounds using multi-dimensional HPLC for medical applications, Molecular Chirality Asia 2020 Online, 2020.11.
31. Kenji HAMASE, Chiral amino acid analysis using multi-dimensional HPLC and medical applications, 第二回台湾薬学合同学術研討会, 2020.11.
32. Chin-Ling HSIEH, Takeyuki AKITA, Masanobu NAGANO, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, 3D-HPLC determination of lactic acid enantiomers in food samples and alteration of their amounts in the plasma after ingesting fermented products, 第31回クロマトグラフィー科学会議, 2020.11.
33. Kenji HAMASE, Multi-dimensional chiral HPLC analysis of amino acids and related compounds in real world samples, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
34. Reiko KOGA, Yohei SAKAGUCHI, Masashi MITA, Tomomi IDE, Hideyuki YOSHIDA, Hitoshi NOHTA, Kenji HAMASE, Development of a three-dimensional HPLC system for the enantioselective determination of urea-cycle amino acids in mammalian urine, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
35. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Two-dimensional HPLC-MS/MS determination of intrinsic chiral amino acids in the plasma of mammals with various D-amino acid oxidase activities, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
36. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Development of a validated three-dimensional chiral HPLC system for the determination of lactate and 3-hydroxybutyrate in human plasma, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
37. Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Kenji HAMASE, Enantioselective three-dimensional HPLC determination of amino acids in carbonaceous meteorites, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
38. Karina Akemy IKEJIRI, Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, 2D-HPLC determination of serine, alanine and aspartic acid enantiomers as their DBD derivatives in the human physiological fluids and food samples, 第30回クロマトグラフィー科学会議, 2019.12.
39. Reiko KOGA, Haruka KAJIKI, Yohei SAKAGUCHI, Masashi MITA, Tomomi IDE, Hideyuki YOSHIDA, Hitoshi NOHTA, Kenji HAMASE,, Determination of urea-cycle-related amino acid enantiomers in human physiological fluids using a three-dimensional HPLC system, The 4th International Conference of D-Amino Acid Research, 2019.09.
40. Jumpei SASABE, Masataka SUZUKI, Yusuke GONDA, Chiharu ISHII, Maiko NAKANE, Masashi MITA, Kenji HAMASE, Metabolism of microbial D-amino acids in mammals, The 4th International Conference of D-Amino Acid Research, 2019.09.
41. Yukiko SHIMIZU, Reiko YANOBU-TAKANASHI, Kenji HAMASE, Establish of a new D-amino acid oxidase (Dao) deficient rat, The 4th International Conference of D-Amino Acid Research, 2019.09.
42. Po-Yeh LIN, Chin‐Ling HSIEH, Chia-Yu LIN, Shih-Ming CHEN, Shiow-Yunn SHEU, Kenji HAMASE, Jen-Ai LEE, Determination of urinary lactate and 3-hydroxybutyrate enantiomers in nephrotoxic serum nephritis mice with saikosaponin C treatment, The 4th International Conference of D-Amino Acid Research, 2019.09.
43. Yusuke GONDA,Masataka SUZUKI, Marina YAMADA, Arno A. VANDEBROEK, Masashi MITA, Kenji HAMASE, Masato YASUI, Jumpei SASABE, Serum D-serine accumulation after proximal renal tubular damage involves neutral amino acid transporter Asc-1, The 4th International Conference of D-Amino Acid Research, 2019.09.
44. Takeyuki AKITA, Natsuki YOSHIOKA,Masashi MITA, Kenji HAMASE, Chiral recognition mechanism of pirkle-type stationary phases in D-amino acid analyses, The 4th International Conference of D-Amino Acid Research, 2019.09.
45. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Enantioselective analysis of lactate and 3-hydroxybutyrate in human samples using a selective and stable 3D-HPLC system, The 4th International Conference of D-Amino Acid Research, 2019.09.
46. Natsuki YOSHIOKA, Shoto ISHIGO, Takeyuki AKITA, Masashi MITA, Kenji HAMASE, Rapid two-dimensional HPLC analysis of D-serine in the human plasma using a high-performance chiral stationary phase, The 4th International Conference of D-Amino Acid Research, 2019.09.
47. Kenji HAMASE, Enantioselective and multi-dimensional HPLC analysis of amino acids as their free/protein bound forms for the screening of novel biomarkers, 30th International Symposium on Pharmaceutical and Biomedical Analysis , 2019.09.
48. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE,Kenji HAMASE, Development of a highly selective two-dimensional HPLC-MS/MS system for the screening of intrinsic D-amino acids in human clinical samples, 30th International Symposium on Pharmaceutical and Biomedical Analysis, 2019.09.
49. Atsushi HESAKA, Shinsuke SAKAI, Kenji HAMASE, Tatsuhiko IKEDA, Rakan MATSUI, Masashi MITA, Masaru HORIO, Yoshitaka ISAKA, Tomonori KIMURA, The intra-body dynamics of D-serine reflects kidney function and disease, The 4th International Conference of D-Amino Acid Research, 2019.09.
50. Sui-Wen HSIAO, #Chiharu ISHII,# Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Tomomi IDE,Ching-Kuo LEE, Kenji HAMASE, Determination of phenylalanine enantiomers in mammalian plasma and urine using two-dimensional HPLC, 第32回バイオメディカル分析科学シンポジウム, 2019.08.
51. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Enantioselective determination of lactate and 3-hydroxybutyrate in human clinical samples using a 3D-HPLC system, 第56回化学関連支部合同九州大会, 2019.07.
52. Kenji HAMASE,Aogu FURUSHO, Chin-Ling HSIEH, Reiko KOGA, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Wolfgang LINDNER, Multi-dimensional HPLC analysis of chiral α-amino acids and carboxylic acids in extraterrestrial materials, 31st International Symposium on Chirality, 2019.07.
53. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Design and development of a highly selective chiral 3D-HPLC system for the determination of lactate and 3-hydroxybutyrate enantiomers in human physiological fluids, 31st International Symposium on Chirality, 2019.07.
54. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Multi-dimensional HPLC determination of lactate and 3-hydroxybutyrate enantiomers and application to human physiological fluids, 第37回九州分析化学若手の会 夏季セミナー, 2019.07.
55. Chin-Ling HSIEH, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Three-dimensional HPLC determination of lactate and 3-hydroxybutyrate enantiomers in mammalian urine, 第26回クロマトグラフィーシンポジウム, 2019.06.
56. Kenji HAMASE, Reiko KOGA, Masashi MITA, Tomomi IDE, Wolfgang LINDNER, Three-dimensional HPLC analysis of chiral amino acids, peptides and carboxylic acids in human clinical samples, 48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2019.06.
57. Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Kenji HAMASE, Three-dimensional chiral HPLC analysis of extraterrestrial amino acids in carbonaceous chondrites, 48th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2019.06.
58. Kenji HAMASE, Enantioselective multi-dimensional HPLC analysis of amino acids and related compounds in complex matrices; Application to food and extraterrestrial samples, 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
59. Chiharu ISHII, Takeyuki AKITA, Masashi MITA,Kenji HAMASE, Determination of D-amino acids in fermented products using an automated two-dimensional HPLC-MS/MS system, 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
60. Chidchanok RUJIRACHATKUL, Natsuki YOSHIOKA, Takeyuki AKITA, Masanobu NAGANO, Masashi MITA, Tomomi IDE, Boonchoo SRITULARAK, Kenji HAMASE, Two-dimensional HPLC separation of D-Ser, D-Ala and D-Asp in human physiological fluids and fermented products using a high performance Pirkle-type enantioselective column, 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
61. Pornpoj PHRUTTIWANICHAKUN, Takeyuki AKITA, Masanobu NAGANO,Masashi MITA, Kenji HAMASE, Development of a two-dimensional HPLC system for the analysis of β-alanine, γ-aminobutyric acid and related amino acid enantiomers in Japanese traditional black vinegar (Kurozu), 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
62. Kenta SAKAI, Takeyuki AKITA,Masashi MITA, Tomomi IDE,Kenji HAMASE, Development of an online two-dimensional HPLC system for leucine skeletal isomers and their enantioselective determination in mammals, 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
63. Miho TAKAHASHI, Aogu FURUSHO, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development of a three-dimensional HPLC system for the determination of acidic amino acid enantiomers in human physiological fluids, 35th International Annual Meeting in Pharmaceutical Sciences (IAMPS35) and CU-MPU International Collaborative Research Conference, 2019.03.
64. Kenji HAMASE, Chiral amino acid analysis using 2D/3D-HPLC for the screening of functional molecules and biomarkers, 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019), 2019.03.
65. Kenji HAMASE, Chiharu ISHII, Aogu FURUSHO, Reiko KOGA, Takeyuki AKITA, Masashi MITA, Masanobu NAGANO, Tomomi IDE, Tomonori KIMURA, Wolfgang LINDNER, Chiral amino acid metabolomics studies using two/three-dimensional HPLC for the screening of new biomarkers and designing functional foods/beverages, The 11th International Symposium on Drug Analysis & The 29th International Symposium on Pharmaceutical and Biomedical Analysis, 2018.09.
66. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development and validation of an on-line two-dimensional HPLC-MS/MS system for the determination of intrinsic chiral amino acids in human physiological fluids, The 11th International Symposium on Drug Analysis & The 29th International Symposium on Pharmaceutical and Biomedical Analysis, 2018.09.
67. Kenji HAMASE, Chiral amino acid analysis using multi-dimensional HPLC: A new frontier of the amino acid and protein research, 15th Conference of the International Society of Tryptophan Research, 2018.09.
68. Takeyuki AKITA, Asumi YOSHIDA, Masashi MITA, Akio OJIDA, Kenji HAMASE, A novel fluorescence derivatizing reagent for chiral amino acid metabolome analysis including tryptophan with high emission intensity, 15th Conference of the International Society of Tryptophan Research, 2018.09.
69. Po-Yeh LIN, Chin-Ling HSIEH, Shin-Ming CHEN, Chia-En LIN, Chia-Yu LIN,Kenji HAMASE, Jen-Ai LEE , Analysis of 3-hydroxybutyrate enantiomers in the urine and serum of mice model of accelerated nephrotoxic serum nephritis, 第31回バイオメディカル分析科学シンポジウム, 2018.08.
70. Takeyuki AKITA, Kenji UEKI, Masashi MITA, Kenji HAMASE, Design and development of multi-mode HPLC stationary phases for chiral separation of amino acids and related compounds, 25th International Symposium on Electro-and Liquid Phase-Separation Techniques, 2018.08.
71. Reiko KOGA, Ena YANO, Tomoko SHINOJIMA, Masashi MITA, Tomomi IDE, Hideyuki YOSHIDA,Hitoshi NOHTA, Kenji HAMASE, Enantioselective and simultaneous 2D-HPLC determination of citrulline and homocitrulline in human clinical samples, 47th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2018.08.
72. Kenji HAMASE, Reiko KOGA, Aogu FURUSHO, Chin-Ling HSIEH, Nutchaya SEREEKITTIKUL, Takeyuki AKITA, Masashi MITA, Tomomi IDE,Jen-Ai LEE, Wolfgang LINDNER, Three-dimensional chiral HPLC analysis of amino acids and related compounds in complex biological matrices including human clinical samples, 47th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2018.08.
73. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Selective screening of free D-amino acids in the physiological fluids and D-form residues in the proteins using an automated two-dimensional HPLC-MS/MS system, 2018 Sino-Japanese Joint Symposium on Separation Sciences, 2018.07.
74. Aogu Furusho, Reiko KOGA, Takeyuki AKITA, Masashi MITA, Tomonori KIMURA, Kenji HAMASE, Development of a three-dimentional HPLC system and application to the chiral amino acid analysis in the plasma of patients with kidney difunction, 2018 Sino-Japanese Joint Symposium on Separation Sciences, 2018.07.
75. Kenji HAMASE, Multi-dimensional chiral HPLC: A promising approach to expand the frontier of amino acid, peptide and protein research, 2018 Sino-Japanese Joint Symposium on Separation Sciences, 2018.07.
76. Aogu FURUSHO, Reiko KOGA, Takeyuki AKITA, Masashi MITA, Tomonori KIMURA, Kenji HAMASE, Three-dimensional HPLC analysis of chiral amino acids in the plasma of patients with chronic kidney disease, 47th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2018.07.
77. Kenji HAMASE, Multi-dimensional HPLC with fluorescence detection as a promising method for trace analysis of chiral amino acids and hydroxy acids in clinical, food and extraterrestrial samples, XVIII International Symposium on Luminescence Spectrometry, 2018.06.
78. Chin-Ling HSIEH, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Development of a three-dimensional HPLC system with fluorescence detection for the simultaneous determination of lactate and 3-hydroxybutyrate enantiomers in human clinical samples, XVIII International Symposium on Luminescence Spectrometry, 2018.06.
79. Pitchapa PUTRAKUL, Nutchaya SEREEKITTIKUL, Chiharu ISHII, Panitch BOONSNONGCHEEP, Kenji HAMASE, Benyakan PONGKITWITOON, Development of a microbore reverse-phase HPLC for determination of capsaicinoids in Capsicum extracts, The 5th International Conference on Current Drug Development 2018 (CDD 2018) and The 3rd International Conference on Herbal and Traditional Medicine 2018 (HTM 2018), 2018.05.
80. Chiharu ISHII,Masashi MITA,Takeyuki AKITA,Tomomi IDE,Kenji HAMASE, Development of a fully automated two-dimensional HPLC-MS/MS system for the determination of amino acid enantiomers in human physiological fluids and fermented beverages, 34th International Annual Meeting In Pharmaceutical Sciences & 2nd CU FPHS-RIKEN CDB Symposium, 2018.03.
81. Siralak LAORATANAPONG,Nutchaya SEREEKITTIKUL,Kenji UEKI,Takeyuki AKITA,Masashi MITA,Tomomi IDE,Boonchoo SRITULARAK,Kenji HAMASE, Two-dimensional HPLC analysis of Asp-Gly and Gly-Asp enantiomers in human samples and fermented products, 34th International Annual Meeting In Pharmaceutical Sciences & 2nd CU FPHS-RIKEN CDB Symposium, 2018.03.
82. Kenji HAMASE, Takeyuki AKITA, Masashi MITA, Hiroshi NARAOKA, Wolfgang LINDNER, Multi-dimensional chiral HPLC analysis of amino acids in clinical samples and extraterrestrial materials, 46th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.11.
83. Kenta SAKAI, Kenji UEKI, Reiko KOGA, Yurika MIYOSHI, Takeyuki AKITA, Masashi MITA, Ryuichi KONNO, Tomomi IDE, Kenji HAMASE, Development of a two-dimensional chiral HPLC system for leucine structural isomers and determination of their urinary levels, 46th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.11.
84. Nutchaya SEREEKITTIKUL, Reiko KOGA, Aogu FURUSHO, Roland REISCHL, Masashi MITA, Masanobu NAGANO, Tomomi IDE, Wolfgang LINDNER, Kenji HAMASE, Multi-dimensional HPLC analysis of serine containing chiral depeptides in human physiological fluids and fermented products, 46th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.11.
85. Aogu FURUSHO, Reiko KOGA, Yurika MIYOSHI, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Design and development of a three-dimensional HPLC system for chiral amino acid analysis in human clinical samples, 46th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.11.
86. Nutchaya SEREEKITTIKUL, Reiko KOGA, Aogu FURUSHO, Roland REISCHL, Masashi MITA, Wolfgang LINDNER, Kenji HAMASE, Development of the multi-dimensional HPLC system for serine containing chiral dipeptides and application to clinical/food samples, 第35回九州分析化学若手の会夏季セミナー, 2017.07.
87. Bing ZHAO, Takeyuki AKITA, Aogu FURUSHO, Masashi MITA, Kenji HAMASE, Characterization of NBD-amino acids with low fluorescence intensities and application to enantioselective HPLC analysis, 第35回九州分析化学若手の会夏季セミナー, 2017.07.
88. Kenji HAMASE, Reiko KOGA, Yurika MIYOSHI, Masashi MITA, Jen-Ai LEE, Wolfgang LINDNER, Multi-dimensional HPLC analysis of D-amino acids and related compounds in complicated biological matrices and its clinical applications, The 3rd International Conference of D-Amino Acid Research, 2017.07, 臨床試料、食品試料、宇宙試料など、様々なサンプルにおいて格段に分離能が向上した三次元HPLCシステムを構築し、その有用性を報告した。.
89. Reiko KOGA, Yu SATO, Masashi MITA, Hiroshi NARAOKA, Kenji HAMASE, Multi-dimensional HPLC analysis of extraterrestrial amino acid enantiomers in various cosmic samples, The 3rd International Conference of D-Amino Acid Research, 2017.07.
90. Chin-Ling HSIEH, Aogu FURUSHO, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Enantioselective and simultaneous determination of lactate and 3-hydroxybutyrate in human clinical samples using a narrowbore two-dimensional HPLC system, The 3rd International Conference of D-Amino Acid Research, 2017.07.
91. Kenji HAMASE, Reiko KOGA, Yurika MIYOSHI, Masashi MITA, Wolfgang LINDNER, Three-dimensional HPLC analysis of amino acid enantiomers in complicated real world samples, 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.06.
92. Chiharu ISHII, Tetsuya MIYAMOTO, Shoto ISHIGO, Masashi MITA, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Accumulation of D-amino acid residues in various proteins during storage, 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.06.
93. Kenji UEKI, Takeyuki AKITA, Yasuhiko KADOTA, Yasuhiro NISHIO, Yurika MIYOSHI, Masashi MITA, Akio OJIDA, Kenji HAMASE, Development of high resolusion Pirkle-type chiral stationary phases and application to D-amino acid analysis in biological matrices, 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.06.
94. Chin-Ling HSIEH, Aogu FURUSHO, Masashi MITA, Tomomi IDE, Jen-Ai LEE, Kenji HAMASE, Development of a two-dimensional HPLC system for the simultaneous determination of lactate and 3-hydroxybutyrate enantiomers in biological matrices including human clinical samples, 第24回クロマトグラフィーシンポジウム, 2017.06.
95. Kenji HAMASE, Multi-dimensional HPLC analysis of chiral amino acids for drug discovery and diagnosis, The JSPS-NRCT Follow-Up Seminar 2017 and 33rd International Annual Meeting in Pharmaceutical Sciences, 2017.03.
96. Kenji HAMASE, Reiko KOGA, Takeyuki AKITA, Yurika MIYOSHI, Masashi MITA, Hiroshi Naraoka, Wolfgang LINDNER, Chiral amino acid metabolomics using multi-dimensional, XVII International Symposium on Luminescence Spectrometry, 2016.11.
97. Yurika MIYOSHI, Maiko NAKANE, Yoshikazu SUGITO, Yosuke TOJO, Reiko KOGA, Masanobu NAGANO, Masashi MITA, Kenji HAMASE, Two-demensional HPLC-FL determination of chiral amino acids in foodstuffs, XVII International Symposium on Luminescence Spectrometry, 2016.11.
98. Yuki MAEDA, Yu SATO, Reiko KOGA, Yurika MIYOSHI, Yasuhiko KADOTA, Yasuhiro NISHIO, Masashi MITA, Kenji HAMASE, Development of a highly sensitive micro-2D-HPLC system for chiral amino acid metabolomics, XVII International Symposium on Luminescence Spectrometry, 2016.11.
99. Kenji UEKI, Takeyuki AKITA, Yu SATO, Reiko KOGA, Yasuhiko KADOTA, Yasuhiro NISHIO, Yurika MIYOSHI, Masashi MITA, Akio OJIDA, Kenji HAMASE, Design of a novel high resolution Pirkle-type chiral stationary phase and separation of NBD-amino acid enantiomers, XVII International Symposium on Luminescence Spectrometry, 2016.11.
100. Kentaro KOBAYASHI, Yumi IWASHITA, Reiko KOGA, Yurika MIYOSHI, Muneki ISOKAWA, Masashi MITA, Makoto TSUNODA, Tadashi Ueda, Kenji HAMASE, Simultaneous determination of sulfur-containing amino acid stereoisomers using a 2D-HPLC system in the urine of homocystinuria model with cystathionine β-synthase deficiency, XVII International Symposium on Luminescence Spectrometry, 2016.11.
101. Reiko KOGA, Yu SATO, Kenji UEKI, Yasuhiko KADOTA, Yasuhiro NISHIO, Masashi MITA, Tomomi IDE, Kenji HAMASE, Design and development of an enansioselective three-dimensional HPLC system for the highly selective fluorescence determination of chiral amino acids, XVII International Symposium on Luminescence Spectrometry, 2016.11.
102. Yu SATO, Reiko KOGA, Masashi MITA, Hiroshi NARAOKA, Kenji HAMASE, Enantioselective two-dimensional HPLC determination of α-amino acids in extraterrestrial samples, XVII International Symposium on Luminescence Spectrometry, 2016.11.
103. Nutchaya SEREEKITTIKUL, Karen Naomi IKEJIRI, Aogu FURUSHO, Reiko KOGA, Roland REISCHL, Masashi MITA, Wolfgang LINDNER, Kenji HAMASE, Two-dimensional HPLC analysis of serine containing chiral peptides, 第27回クロマトグラフィー科学会議, 2016.11.
104. Karen Naomi IKEJIRI, Reiko KOGA, Aogu FURUSHO, Masashi MITA, Kenji HAMASE, Development of a 2D-HPLC system for enantioselective determination of chiral dipeptides containing alanine, 第27回クロマトグラフィー科学会議, 2016.11.
105. Kenji HAMASE, Reiko KOGA, Yurika MIYOSHI, Masashi MITA, Wolfgang LINDNER, Chiral amino acid analysis: New frontier of drug discovery and diagnosis, 27th International Symposium on Pharmaceutical and Biomedical Analysis, 2016.11.
106. Chiharu ISHII, Shoto ISHIGO, Tetsuya MIYAMOTO, Yurika MIYOSHI, Masashi MITA, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Determination of D-amino acid residues in proteins stored under various pH conditions, 27th International Symposium on Pharmaceutical and Biomedical Analysis, 2016.11.
107. Kenji HAMASE, Yurika MIYOSHI, Masashi MITA, Wolfgang LINDNER, Chiral amino acid targeted metabolomics as a new strategy for biomarker screening and designing functional foods/beverages, 44th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2016.06.
108. Yuko SAITSU, Yurika MIYOSHI, Yu SATO, Eiichi NEGISHI, Takafumi SUMIYAMA, Masanobu NAGANO, Masashi MITA, Kenji HAMASE, Development of a 2D-HPLC system for NBD-amino acids using a blue LED fluorescence detector and determination of amino acid enantiomers in fermented products, 44th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2016.06.
109. Reiko KOGA, Yurika MIYOSHI, Yu SATO, Masashi MITA, Ryuichi KONNO, Wolfgang LINDNER, Kenji HAMASE, Enantioselective 2D-HPLC determination of citrulline and ornithine in the urine of D-amino acid oxidase deficient mice, 44th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2016.06.
110. Yu-Chun CHIU, Jen-Ai LEE, Shih-Ming CHEN, Yurika MIYOSHI, Yu SATO, Masashi MITA, Masanobu NAGANO, Tomomi IDE, Kenji HAMASE, Simultaneous determination of lactate and 3-hydroxybutyrate enantiomers using a 2D-HPLC system with various Pirkle-type columns, 第23回クロマトグラフィーシンポジウム, 2016.06.
111. Kenji HAMASE, Yurika MIYOSHI, Masashi MITA, Wolfgang LINDNER, Chiral amino acid metabolomics for drug discovery, clinical diagnosis and designing functional foods/ beverages, 26th International Symposium on Pharmaceutical and Biomedical Analysis, 2015.07.
112. Yurika MIYOSHI, Jumpei SASABE, Masataka SUZUKI, Yayoi YONENAGA, Yu SATO, Maiko NAKANE, Masashi MITA, Sadakazu AISO, Kenji HAMASE, Two-dimensional HPLC-FL/MS/MS determination of chiral amino acids in physiological fluids of model mice of ischemic acute kidney injury, 26th International Symposium on Pharmaceutical and Biomedical Analysis, 2015.07.
113. Kenji HAMASE, Yurika MIYOSHI, Yayoi YONENAGA, Hirohisa ONIGAHARA, Yusuke ITO, Masashi MITA, Jumpei SASABE, Sadakazu AISO, Wolfgang LINDNER, Chiral amino acid targeted metabolomics for clinical diagnosis using enantioselective two-dimensional HPLC tandem-mass spectrometry, 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2015.06.
114. Soto ISHIGO, Eiichi NEGISHI, Yurika MIYOSHI, Hirohisa ONIGAHARA, Masashi MITA, Tadashi UEDA, Kenji HAMASE, Determination of trace levels of D-Asp and D-Glu residues in proteins using a two-dimensional HPLC-MS/MS system, 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2015.06.
115. Reiko KOGA, Yurika MIYOSHI, Hirohisa ONIGAHARA, Masashi MITA, Ryuichi KONNO, Wolfgang LINDNER, Kenji HAMASE, Enantioselective determination of phenylalanine, tyrosine and 3,4-dihydroxyphenylalanine in the model mice with metabolic disorders, 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2015.06.
116. Kenji HAMASE, Chiral amino acid metabolomics for clinical diagnosis, Molecular Chirality Asia 2014, 2014.10.
117. Soto ISHIGO, Reina FUJITA, Yurika MIYOSHI, Eiichi NEGISHI, Hirohisa ONIGAHARA, Masashi MITA, Tetsuya MIYAMOTO, Haruhiko MASAKI, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Determination of trace amounts of D-amino acid residues in proteins using a two-dimensional chiral HPLC-MS/MS system, Molecular Chirality Asia 2014, 2014.10.
118. Kenji HAMASE, Yurika MIYOSHI, Jumpei SASABE, Tomonori KIMURA, Masashi MITA, Ryohei YAMAMOTO, Yoshitaka ISAKA, Sadakazu AISO, Wolfgang LINDNER, Chiral amino acid metabolomics using two-dimensional HPLC for novel biomarker screening, 30th International Symposium on Chromatography, 2014.09, 二次元HPLCを用いるキラルアミノ酸メタボロミクスを利用し、新たなバイオマーカーの探索を行っている。技術開発および実際の精神神経疾患、腎不全などのマーカー探索を行なった結果を発表した。.
119. Sachi YOKOI, Yurika MIYOSHI, Eiichi NEGISHI, Masashi MITA, Tadashi UEDA, Kenji HAMASE, Development of a two-dimensional chiral HPLC system for the simultaneous determination of cystine isomers, 30th International Symposium on Chromatography, 2014.09.
120. Yurika MIYOSHI, Nao KUSANO, Yayoi YONENAGA, Hirohisa ONIGAHARA, Jumpei SASABE, Eiichi NEGISHI, Maiko NAKANE, Masashi MITA, Tomonori KIMURA, Ryohei YAMAMOTO, Yoshitaka ISAKA, Sadakazu AISO, Kenji HAMASE, Enantioselective determination of all proteinogenic amino acids in the serum and urine of patients/mice with renal dysfunction using a two-dimensional HPLC-FL/MS/MS system, 30th International Symposium on Chromatography, 2014.09.
121. Hirohisa ONIGAHARA, Nao KUSANO, Yurika MIYOSHI, Yasuhiko KADOTA, Yasuhiro NISHIO, Masashi MITA, Akio OJIDA, Wolfgang LINDNER, Kenji HAMASE, Design and development of novel high-performance Pirkle-type stationary phases for chiral amino acid metabolomics studies, 30th International Symposium on Chromatography, 2014.09.
122. Tsubasa OYAMA, Eiichi NEGISHI, Nao KUSANO, Hirohisa ONIGAHARA, Yurika MIYOSHI, Masashi MITA, Sumio OHTSUKI, Akio OJIDA, Wolfgang LINDNER, Kenji HAMASE, Development of a 2D-HPLC system for chiral amino acid analysis using a novel FL/MS/MS reagent with 6-methoxy-4-quinolone moiety, 30th International Symposium on Chromatography, 2014.09.
123. Yurika MIYOSHI, Eiichi NEGISHI, Masanobu NAGANO, Jumpei SASABE, Maiko NAKANE, Masashi MITA, Ryuichi KONNO, Sadakazu AISO, Kenji HAMASE, Chiral amino acid metabolomics using two-dimensional HPLC focusing on neuro-active amino acids, The 2nd International Conference of D-Amino Acid Research, 2014.09.
124. Shoto ISHIGO, Reina FUJITA, Yurika MIYOSHI, Eiichi NEGISHI, Hirohisa ONIGAHARA, Masashi MITA, Tetsuya MIYAMOTO, Haruhiko MASAKI, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Establishment of a two-dimensional chiral HPLC-MS/MS system for the determination of trace amounts of D-amino acid residues in proteins, The 2nd International Conference of D-Amino Acid Research, 2014.09.
125. Tsubasa OYAMA, Eiichi NEGISHI, Hirohisa ONIGAHARA, Yurika MIYOSHI, Masashi MITA, Sumio OHTSUKI, Akio OJIDA, Wolfgang LINDNER, Kenji HAMASE, Establishment of a 2D-HPLC system for chiral amino acid metabolomics using a novel FL/MS/MS reagent with 6-methoxy-4-quinolone moiety and its deuterated analog, The 2nd International Conference of D-Amino Acid Research, 2014.09.
126. Reiko KOGA, Yurika MIYOSHI, Hirohisa ONIGAHARA, Masashi MITA, Wolfgang LINDNER, Kenji HAMASE, Establishment of a 2D-HPLC system for the enantioselective determination of aromatic amino acids, The 2nd International Conference of D-Amino Acid Research, 2014.09.
127. Hirohisa ONIGAHARA, Nao KUSANO, Yurika MIYOSHI, Yasuhiko KADOTA, Yasuhiro NISHIO, Masashi MITA, Akio OJIDA, Wolfgang LINDNER, Kenji HAMASE, Development of novel high-performance Pirkle-type chiral stationary phases having branched aliphatic amino acids, The 2nd International Conference of D-Amino Acid Research, 2014.09.
128. Yayoi YONENEGA, Yurika MIYOSHI, Hirohisa ONIGAHARA, Eiichi NEGISHI, Masashi MITA, Jumpei SASABE, Sadakazu AISO, Kenji HAMASE, Chiral amino acid metabolomics of human urine using two-dimensional high-performance liquid chromatography, The 2nd International Conference of D-Amino Acid Research, 2014.09.
129. Kenji HAMASE, Yurika MIYOSHI, Tomonori KIMURA, Jumpei SASABE, Nao KUSANO, Hirohisa ONIGAHARA, Masashi MITA, Ryohei YAMAMOTO, Yoshitaka ISAKA, Sadakazu AISO, Wolfgang LINDNER, Chiral amino acid metabolomics for the diagnosis of renal disorders using an enantioselective 2D-HPLC-FL/MS/MS system, 41st International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2014.05.
130. Shu-Ling Liu, Jen-Ai Lee, Shiow-Yunn Sheu, Tsubasa Oyama, Yurika MIYOSHI, Masashi Mita, Kenji Hamase, Development of a two-dimensional HPLC system for the simultaneous determination of lactate and 3-hydroxybutyrate enantiomers, 日本薬学会第134年会 , 2014.03.
131. Kenji Hamase, Yusuke ITO, Hirohisa ONIGAHARA, Nao KUSANO, Yurika MIYOSHI, Masashi MITA, Wolfgang LINDNER, Chiral amino acid metabolomics for the sensitive diagnosis of metabolic disorders, 40th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2013.11.
132. Yurika MIYOSHI, Masanobu NAGANO, Yusuke ITO, Shoto ISHIGO, Kazunori HASHIGUCHI, Naoto HISHIDA, Eiichi NEGISHI, Maiko NAKANE, Masashi MITA, Kenji Hamase, Determination of D-amino acids in the Japanese traditional amber rice vinegar “Kurozu” by using a 2D-HPLC-FL/MS/MS system, 40th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 2013.11.
133. Kenji HAMASE, Yurika MIYOSHI, Nao KUSANO, Jumpei SASABE, Yosuke TOJO, Masashi MITA, Sadakazu AISO, Wolfgang LINDNER, Chiral amino acid metabolome analysis for biomarker assay in clinical diagnosis using enantioselective 2D-HPLC, 39th International Symposium on High-Performance Liquid Phase Separations and Related Techniques , 2013.06.
134. Nao KUSANO, Jumpei SASABE, Hirohisa ONIGAHARA, Yurika MIYOSHI, Masashi MITA, Sadakazu AISO, Wolfgang LINDNER, Kenji HAMASE, Simultaneous two-dimensional high-performance liquid chromatographic determination of all proteinogenic amino acid enantiomers in human serum using high performance Pirkle-type chiral stationary phases, 39th International Symposium on High-Performance Liquid Phase Separations and Related Techniques , 2013.06.
135. Tsubasa OYAMA, Eiichi NEGISHI, Nao KUSANO, Hirohisa ONIGAHARA, Yurika MIYOSHI, Masashi MITA, Manabu NAKAZONO, Sumio OHTSUKI, Akio OJIDA, Wolfgang LINDNER, Kenji HAMASE, Design and synthesis of a novel reagent with 6-MOQ moiety for amino acid labeling and chiral separations of all proteinogenic amino acids, 39th International Symposium on High-Performance Liquid Phase Separations and Related Techniques , 2013.06.
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