Kyushu University Academic Staff Educational and Research Activities Database
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Motoaki Shiratsuchi Last modified date:2019.12.23

Lecturer / Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences
Department of Endocrine and Metabolic Diseases / Diabetes Mellitus
Kyushu University Hospital


Graduate School
Undergraduate School


E-Mail
Phone
092-642-5281
Fax
092-642-5287
Academic Degree
PhD
Country of degree conferring institution (Overseas)
No
Field of Specialization
Internal Medicine, Hematology, Immunology
ORCID(Open Researcher and Contributor ID)
0000-0002-0403-0122
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
Research) 1.Study of a new pore-forming protein expressed on macrophages
Education) 1.Education of residents of clinical medicine and hematology
Social activities) 1.Clinical works on internal medicine
Research
Research Interests
  • A study of a new pore-forming protein expressed on macrophages
    keyword : macrophage, pore-forming protein, perforin
    2008.12Development of dendritic cell therapy for telomerase catarytic subunit of myeloma cells..
Academic Activities
Papers
1. Ryan M McCormack, Lesley R de Armas, Motoaki Shiratsuchi, Desiree G Fiorentino, Melissa L Olsson, Mathias G Lichtenheld, Alejo Morales, Kirill Lyapichev, Louis E Gonzalez, Natasa Strbo, Neelima Sukumar, Olivera Stojadinovic, Gregory V Plano, George P Munson, Marjana Tomic-Canic, Robert S Kirsner, David G Russell, Eckhard R Podack, Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria., eLife, 10.7554, 2015.09.
2. Junichi Kiyasu, Hiroaki Miyoshi, Akie Hirata, Fumiko Arakawa, Ayako Ichikawa, Daisuke Niino, Yasuo Sugita, Yuji Yufu, Ilseung Choi, Yasunobu Abe, Naokuni Uike, Koji Nagafuji, Takashi Okamura, koichi akashi, Hijioka M, Ito T, Igarashi H, Fujimori N, Lee L, Nakamura T, Jensen RT, Takayanagi R., Motoaki Shiratsuchi, Koichi Oshima, Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma, Blood, 126, 19, 2193-2201, 2015.11.
3. McCormack R, de Armas LR, Motoaki Shiratsuchi, Ramos JE, Podack ER, Inhibition of intracellular bacterial replication in fibroblasts is dependent on the perforin-like protein (perforin-2) encoded by macrophage-expressed gene 1., J Innate Immun, 5, 2, 185-194, 2013.02.
4. Motoaki Shiratsuchi, Koichiro Muta, Yasunobu Abe, Seiichi Motomura, Fumihiro Taguchi, Hiroshi Takatsuki, Naokuni Uike, Tsukuru Umemura, Hajime Nawata, Junji Nishimura, Clinical Significance of Telomerase Activity in Multiple Myeloma, Cancer, 10.1002/cncr.10472, 94, 8, 2232-2238, 94巻、8号、2232頁〜2238頁, 2002.04.
5. Shiratsuchi M, Muta K, Minami R, Motomura S, Suehiro Y, Abe Y, Shiokawa S, Umemura T, Fukui T, Nishimura J, Nawata H, Aberrant BCR-ABL transcript with intronic insertion in a patient with Philadelphia chromosome-positive chronic myeloid leukemia: Implications for disease progression., Leukemia and Lymphoma, 10.3109/10428190109057996, 41, 3-4, 411-415, 41巻、3-4号、411頁〜415頁, 2001.01.
6. Shiratsuchi M, Muta K, Umemura T, Nishimura J, Nawata H, Kozuru M, Telomerase Activity in Myeloma Cells Is Closely Related to Cell Cycle Status, But Not to Apoptotic Signals Induced by Interferon-α., LEUKEMIA LYMPHOMA, 34, 3-4, 349-359, 34巻、3-4号、349頁〜359頁, 1999.01.
Presentations
1. Motoaki Shiratsuchi, Tetsuya Fukuda, Tadafumi Iino, Atsuhiko Hasegawa, Junichirou Yasunaga, Ken Watanabe, Akie Hirata, Hayato Utsunomiya, Hirofumi Ohno, Takashi Ishida, Koichi Akashi, Masao Matsuoka, Mari Kannagi, and Youko Suehiro, Tax-Targeting Dendritic Cell Therapy for ATL: A Phase Ia/Ib Clinical Study, 60th ASH Annual Meeting and Exposition, 2018.12.
2. The value of endothelial function test for the prediction of transplantation-related complications.
Membership in Academic Society
  • The Japanese Society of Internal Medicine
  • Japanese Society of Hematology
  • The Japan Society for Hematopoietic Cell Transplantation
  • The Japan Geriatrics Sciety
  • Japan Society for the Study of Obesity
Educational
Educational Activities
Education of residents on clinical medicine and hematology.
Social
Professional and Outreach Activities
Clinical works on internal medicine..