九州大学 研究者情報
論文一覧
村田 昌之(むらたまさゆき) データ更新日:2024.04.09

准教授 /  医学研究院 臨床医学部門 感染制御医学


原著論文
1. Matsumoto Y, Murata M, Takayama K, Yamasaki S, Hiramine S, Toyoda K, Kibe Y, Nishida R, Kimura S, Sonoda H, Shiose A, Shimono N., A case of mediastinal abscess and infected aortic aneurysm caused by dissemination of Mycobacterium abscessus subsp. massiliense pulmonary disease, J Infect Chemother. 2023 Jan;29(1):82-86. doi: 10.1016/j.jiac.2022.09.017. Epub 2022 Sep 24., 10.1016/j.jiac.2022.09.017. , 29, 1, 82-86, 2023.01.
2. Nindita Y, Nakatochi M, Ibusuki R, Shimoshikiryo I, Nishimoto D, Shimatani K, Takezaki T, Ikezaki H, Murata M, Hara M, Nishida Y, Tamura T, Hishida A, Nagayoshi M, Okada R, Matsuo K, Ito H, Mikami H, Nakamura Y, Otani T, Suzuki S, Koyama T, Ozaki E, Kuriki K, Takashima N, Miyagawa N, Arisawa K, Katsuura-Kamano S, Momozawa Y, Kubo M, Takeuchi K, Wakai K., Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-cholesterol Levels in J-MICC Study Participants, J Epidemiol. 2023 Apr 5;33(4):193-200. doi: 10.2188/jea.JE20210142. Epub 2022 Feb 22., 10.2188/jea.JE20210142., 33, 4, 193-200, 2023.02.
3. Hara M, Nishida Y, Tanaka K, Shimanoe C, Koga K, Furukawa T, Higaki Y, Shinchi K, Ikezaki H, Murata M, Takeuchi K, Tamura T, Hishida A, Tsukamoto M, Kadomatsu Y, Matsuo K, Oze I, Mikami H, Kusakabe M, Takezaki T, Ibusuki R, Suzuki S, Nakagawa-Senda H, Matsui D, Koyama T, Kuriki K, Takashima N, Nakamura Y, Arisawa K, Katsuura-Kamano S, Wakai K., Moderate-to-vigorous Physical Activity and Sedentary Behavior Are Independently Associated With Renal Function: A Cross-sectional Study, J Epidemiol. 2023 Jun 5;33(6):285-293. doi: 10.2188/jea.JE20210155. Epub 2022 Feb 22., 10.2188/jea.JE20210155., 33, 6, 285-293, 2023.02.
4. Sasaki K, Murata M, Nakamura K, Matsumoto Y, Nakashima Y, Yamasaki S, Ota A, Hiramine S, Takayama K, Ikezaki H, Toyoda K, Ogawa E, Shimono N., A case of severe COVID-19 with pulmonary thromboembolism related to heparin-induced thrombocytopenia during prophylactic anticoagulation therapy, J Infect Chemother. 2022 Aug;28(8):1208-1211. doi: 10.1016/j.jiac.2022.05.001. Epub 2022 May 11., 10.1016/j.jiac.2022.05.001., 28, 8, 1208-1211, 2022.08.
5. Matsunaga T, Kadomatsu Y, Tsukamoto M, Kubo Y, Okada R, Nagayoshi M, Tamura T, Hishida A, Takezaki T, Shimoshikiryo I, Suzuki S, Nakagawa H, Takashima N, Saito Y, Kuriki K, Arisawa K, Katsuura-Kamano S, Kuriyama N, Matsui D, Mikami H, Nakamura Y, Oze I, Ito H, Murata M, Ikezaki H, Nishida Y, Shimanoe C, Takeuchi K, Wakai K., Associations of breastfeeding history with metabolic syndrome and cardiovascular risk factors in community-dwelling parous women: The Japan Multi-Institutional Collaborative Cohort Study, PLoS One. 2022 Jan 19;17(1):e0262252. doi: 10.1371/journal.pone.0262252. eCollection 2022., 10.1371/journal.pone.0262252., 2022.01.
6. Fujii R, Hishida A, Nishiyama T, Nakatochi M, Matsuo K, Ito H, Nishida Y, Shimanoe C, Nakamura Y, Turin TC, Suzuki S, Watanabe M, Ibusuki R, Takezaki T, Mikami H, Nakamura Y, Ikezaki H, Murata M, Kuriki K, Kuriyama N, Matsui D, Arisawa K, Katsuura-Kamano S, Tsukamoto M, Tamura T, Kubo Y, Kondo T, Momozawa Y, Kubo M, Takeuchi K, Wakai K., Assessing the Relationship Between High-sensitivity C-reactive Protein and Kidney Function Employing Mendelian Randomization in the Japanese Community-based J-MICC Study, J Epidemiol. 2022 Nov 5;32(11):483-488. doi: 10.2188/jea.JE20200540. Epub 2021 Jul 10., 10.2188/jea.JE20200540., 32, 11, 483-488, 2022.11.
7. Ohta A, Ogawa E, Murata M, Matsumoto Y, Yamasaki S, Ikezaki H, Furusyo N., Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication, J Med Virol. 2022 Oct;94(10):5007-5014. doi: 10.1002/jmv.27904. Epub 2022 Jun 11., 10.1002/jmv.27904., 94, 10, 5007-5014, 2022.10.
8. Kainuma M, Ouma S, Kawakatsu S, Iritani O, Yamashita KI, Ohara T, Hirano S, Suda S, Hamano T, Hieda S, Yasui M, Yoshiiwa A, Shiota S, Hironishi M, Wada-Isoe K, Sasabayashi D, Yamasaki S, Murata M, Funakoshi K, Hayashi K, Shirafuji N, Sasaki H, Kajimoto Y, Mori Y, Suzuki M, Ito H, Ono K, Tsuboi Y., An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer's disease, Front Pharmacol. 2022 Oct 14;13:991982. doi: 10.3389/fphar.2022.991982. eCollection 2022., 10.3389/fphar.2022.991982., 2022.10.
9. Yuki Nakano, Masayuki Murata, Yuji Matsumoto, Kazuhiro Toyoda, Azusa Ota, Sho Yamasaki, Hisao Otakeno, Kenjo Yokoo, Nobuyuki Shimono, Clinical characteristics and factors related to infection with SCCmec type II and IV Methicillin-resistant Staphylococcus aureus in a Japanese secondary care facility: a single-center retrospective study, J Glob Antimicrob Resist, 10.1016/j.jgar.2022.11.003, 31, 355-362, 2022.11.
10. Harumitsu Suzuki, Yasuyuki Nakamura, Keitaro Matsuo, Nahomi Imaeda, Chiho Goto, Akira Narita, Atsushi Shimizu, Naoyuki Takashima, Kenji Matsui , Katsuyuki Miura , Masahiro Nakatochi, Asahi Hishida, Takashi Tamura, Yuka Kadomatsu, Rieko Okada, Yuichiro Nishida, Chisato Shimanoe, Daisaku Nishimoto, Toshiro Takezaki, Isao Oze, Hidemi Ito, Hiroaki Ikezaki, Masayuki Murata, Daisuke Matsui, Etsuko Ozaki, Haruo Mikami, Yohko Nakamura, Sadao Suzuki, Miki Watanabe, Kokichi Arisawa, Hirokazu Uemura, Kiyonori Kuriki, Yukihide Momozawa, Michiaki Kubo, Yoshikuni Kita, Kenji Takeuchi, Kenji Wakai, A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern, Eur J Clin Nutr. , 10.1038/s41430-020-00823-z, 2021 Jun;75(6):937-945. , 2021.07.
11. Taro Suzuki 1 , Yasuyuki Nakamura 2 3 , Yukio Doi 1 , Akira Narita 4 , Atsushi Shimizu 5 , Nahomi Imaeda 6 7 , Chiho Goto 7 8 , Kenji Matsui 9 , Aya Kadota 3 10 , Katsuyuki Miura 3 10 , Masahiro Nakatochi 11 , Keitaro Tanaka 12 , Megumi Hara 12 , Hiroaki Ikezaki 13 14 , Masayuki Murata 14 , Toshiro Takezaki 15 , Daisaku Nishimoto 16 , Keitaro Matsuo 17 , Isao Oze 17 , Nagato Kuriyama 18 , Etsuko Ozaki 18 , Haruo Mikami 19 , Yohko Nakamura 19 , Miki Watanabe 7 , Sadao Suzuki 7 , Sakurako Katsuura-Kamano 20 , Kokichi Arisawa 20 , Kiyonori Kuriki 21 , Yukihide Momozawa 22 , Michiaki Kubo 22 , Kenji Takeuchi 23 , Yoshikuni Kita 3 24 , Kenji Wakai 23 , J-MICC Research Group, A genome-wide association study on confection consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort Study, Br J Nutr. , 10.1017/S0007114521000684, 2021 Dec 28;126(12):1843-1851., 2021.12.
12. Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Daisaku Nishimoto, Keiichi Shimatani, Toshiro Takezaki, Hiroaki Ikezaki, Masayuki Murata, Megumi Hara, Yuichiro Nishida, Takashi Tamura, Asahi Hishida, Mako Nagayoshi, Rieko Okada, Keitaro Matsuo, Hidemi Ito, Haruo Mikami, Yohko Nakamura, Takahiro Otani, Sadao Suzuki, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Naoko Miyagawa, Kokichi Arisawa, Sakurako Katsuura-Kamao, Yukihide Momozawa, Michiaki Kubo, Kenji Takeuchi, Kenji Wakai, Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants, J Epidemiol., 10.2188/jea.JE20210142, 2021.08.
13. Megumi Hara, Yuichiro Nishida, Keitaro Tanaka, Chisato Shimanoe, Kayoko Koga, Takuma Furukawa, Yasuki Higaki, Koichi Shinchi, Hiroaki Ikezaki, Masayuki Murata, Kenji Takeuchi, Takashi Tamura, Asahi Hishida, Mineko Tsukamoto, Yuka Kadomatsu, Keitaro Matsuo, Isao Oze, Mikami Haruo, Kusakabe Miho, Toshiro Takezaki, Rie Ibusuki, Sadao Suzuki, Hiroko Nakagawa-Senda, Daisuke Matsui, Teruhide Koyama, Kiyonori Kuriki, Naoyuki Takashima, Yasuyuki Nakamura, Kokichi Arisawa, Sakurako Katsuura-Kamano, Kenji Wakai, Moderate-to-vigorous physical activity and sedentary behavior are independently associated with renal function: a cross-sectional study, J Epidemiol., 10.2188/jea.JE20210155, 2021.10.
14. Taro Suzuki, Yasuyuki Nakamura, Keitaro Matsuo, Isao Oze, Yukio Doi, Akira Narita, Atsushi Shimizu, Nahomi Imaeda, Chiho Goto, Kenji Matsui, Masahiro Nakatochi, Katsuyuki Miura, Naoyuki Takashima, Kiyonori Kuriki, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki , Masayuki Murata, Rie Ibusuki, Toshiro Takezaki, Yuriko Koyanagi, Hidemi Ito, Daisuke Matsui, Teruhide Koyama, Haruo Mikami, Yohko Nakamura, Sadao Suzuki, Takeshi Nishiyama, Sakurako Katsuura-Kamano, Kokichi Arisawa, Kenji Takeuchi, Takashi Tamura, Rieko Okada, Yoko Kubo, Yukihide Momozawa, Michiaki Kubo, Yoshikuni Kita, Kenji Wakai, J-MICC Research Group, A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study, Eur J Clin Nutr., 10.1038/s41430-020-00702-7, 75, 3, 480-488, 2021.03.
15. 山本 賢, 吉良 雄一, 平峯 智, 林 武生, 橋本 侑, 眞崎 勝久, 松瀬 大, 吉良 潤一, 篠原 啓介, 筒井 裕之, 松本 佑慈, 太田 梓, 山嵜 奨, 高山 耕治, 池崎 裕昭, 豊田 一弘, 小川 栄一, 貝沼 茂三郎, 村田 昌之, 難治性起立性低血圧から診断された自己免疫性自律神経ガングリオノパチーの1例, 日本病院総合診療医学会雑誌 , 17, 3, 298-303, 2021.05.
16. Ikezaki H, Furusyo N, Yokota Y, Ai M, Asztalos BF, Murata M, Hayashi J, Schaefer EJ , Small Dense Low-Density Lipoprotein Cholesterol and Carotid Intimal Medial Thickness Progression
, J Atheroscler Thromb, 10.5551/jat.54130., 27, 10, 1108-1122, 2020.11.
17. Arisawa K, Katsuura-Kamano S, Uemura H, Tien NV, Hishida A, Tamura T, Kubo Y, Tsukamoto M, Tanaka K, Hara M, Takezaki T, Nishimoto D, Koyama T, Ozaki E, Suzuki S, Nishiyama T, Kuriki K, Kadota A, Takashima N, Ikezaki H, Murata M, Oze I, Matsuo K, Mikami H, Nakamura Y, Takeuchi K, Wakai K , Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study.
, Nutrients., 10.3390/nu12061605, 12, 6, 1605, 2020.05.
18. Koyama T, Kuriyama N, Ozaki E, Tomida S, Uehara R, Nishida Y, Shimanoe C, Hishida A, Tamura T, Tsukamoto M, Kadomatsu Y, Oze I, Matsuo K, Mikami H, Nakamura Y, Ibusuki R, Takezaki T, Suzuki S, Nishiyama T, Kuriki K, Takashima N, Kadota A, Uemura H, Katsuura-Kamano S, Ikezaki H, Murata M, Takeuchi K, Wakai K; Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group , Sedentary Time is Associated with Cardiometabolic Diseases in A Large Japanese Population: A Cross-Sectional Study.
, J Atheroscler Thromb., 27, 10, 1097-1107, 2020.10.
19. Madoka Iwase, Keitaro Matsuo, Masahiro Nakatochi, Isao Oze, Hidemi Ito, Yuriko Koyanagi, Tomotaka Ugai, Yumiko Kasugai, Asahi Hishida, Kenji Takeuchi, Rieko Okada, Yoko Kubo, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki, Masayuki Murata, Toshiro Takezaki, Daisaku Nishimoto, Nagato Kuriyama, Etsuko Ozaki , Sadao Suzuki, Miki Watanabe, Haruo Mikami, Yohko Nakamura, Hirokazu Uemura, Sakurako Katsuura-Kamano, Kiyonori Kuriki, Yoshikuni Kita, Naoyuki Takashima , Masato Nagino, Yukihide Momozawa, Michiaki Kubo, Kenji Wakai, Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan Multi-Institutional Collaborative Cohort Study., J Epidemiol., 31, 3, 172-179, 2021.03.
20. 太田 梓, 村田 昌之, 谷合 啓明, 林 真, 意識障害を来したEdwardsiella tarda敗血症、梨状筋膿瘍の1例, 日本病院総合診療医学会雑誌, 17, 1, 72-77, 2021.01.
21. Usui Y, Matsuo K, Oze I, Ugai T, Koyanagi Y, Maeda Y, Ito H, Hishida A, Takeuchi K, Tamura T, Tsukamoto M, Kadomatsu Y, Hara M, Nishida Y, Shimoshikiryo I, Takezaki T, Ozaki E, Matsui D, Watanabe I, Suzuki S, Watanabe M, Nakagawa-Senda H, Mikami H, Nakamura Y, Arisawa K, Uemura H, Kuriki K, Takashima N, Kadota A, Ikezaki H, Murata M, Nakatochi M, Momozawa Y, Kubo M, Wakai K, Impact of PSCA polymorphisms on the risk of duodenal ulcer, J Epidemiol, doi: 10.2188/jea.JE20190184, 31, 1, 12-20, 2021.01.
22. Masaki Kakimoto, Masayuki Murata, Fujiko Mitsumoto-Kaseida, Eiichi Ogawa, Yuji Matsumoto, Akira Kusaga, Kazuhiro Toyoda, Takeo Hayashi, Kazuya Ura, Keishi Kanno, Norihiro Furusyo, Susumu Tazuma, Toxocariasis suspected of having infiltrated directly from the liver to the lung through the diaphragm, Internal Medicine, 10.2169/internalmedicine.2716-19, 58, 18, 2737-2741, 2019.09, [URL], A 37-year-old woman presented to our hospital with mild abdominal pain experienced for 2 months and hepatic nodules in segments 3 and 8. Peripheral blood eosinophilia was observed, and toxocariasis was serologically diagnosed. Seventeen days after the first imaging evaluation, a new lesion was found in segment 9 of the right lung, which was contiguous through the diaphragm to the hepatic nodule in segment 8. After treatment with albendazole, the liver and lung nodules disappeared. We suspect that larvae had directly invaded the lung from the liver, through the diaphragm..
23. Fujiko Mitsumoto-Kaseida, Masayuki Murata, Koji Takayama, Kazuhiro Toyoda, Eiichi Ogawa, Norihiro Furusyo, Jun Hayashi, Prevalence and characteristics of occult hepatitis B virus infection in Japanese human immunodeficiency virus-infected patients, Journal of Infection and Chemotherapy, 10.1016/j.jiac.2019.06.003, 26, 1, 28-32, 2020.01, [URL], Occult hepatitis B virus (HBV) infection (OBI) is hepatitis B surface antigen (HBsAg) negative but with detectable HBV DNA. Although HIV infection has been reported to be a risk factor for OBI, the prevalence and clinical features of OBI in Japanese HIV infected patients have not been documented. This retrospective, single-center study was conducted to determine the prevalence and characteristic of OBI in Japanese antiretroviral therapy (ART) naïve HIV infected patients. OBI was defined as the presence of serum HBV DNA but without detectable HBsAg. Of the 147 ART naïve HIV infected patients, OBI was detected in 9 (6.1%) patients; 2 (4.3%) of 47 with both anti-HBs and anti-HBc positive, 6 (27.3%) of 22 with anti-HBc alone, and 1 (2.0%) of 50 with both anti-HBs and anti-HBc negative. The mean HBV DNA level was low at 28.7 ± 18.2 IU/mL. The proportion of OBI patients with anti-HBc alone was significantly higher than that of non-OBI patients (66.7% vs 14.5%, P = 0.001). In addition, the prevalence of AIDS (acquired immunodeficiency syndrome)-defining illnesses in the OBI group was significantly higher than in the non-OBI group (77.8% vs 35.5%, P = 0.001). No significant difference was found in the CD4 count or alanine aminotransferase levels of these two groups. This is the first study to reveal the prevalence and clinical features of OBI in Japanese HIV-infected patients. The persistence of anti-HBc alone and AIDS-defining illnesses were associated with the occurrence of OBI in these patients..
24. Fujii R, Hishida A, Nakatochi M, Furusyo N, Murata M, Tanaka K, Shimanoe C, Suzuki S, Watanabe M, Kuriyama N, Koyama T, Takezaki T, Shimoshikiryo I, Arisawa K, Katsuura-Kamano S, Takashima N, Turin TC, Kuriki K, Endoh K, Mikami H, Nakamura Y, Oze I, Ito H, Kubo M, Momozawa Y, Kondo T, Naito M, Wakai K., Association of genetic risk score and chronic kidney disease in a Japanese population.
, Nephrology (Carlton), 10.1111/nep.13479, 2018.08.
25. 山下 有加, 諸熊 由子, 持丸 朋美, 西田 留梨子, 清祐 麻紀子, 堀田 多恵子, 村田 昌之, 下野 信行, 康 東天, GENECUBEで偽陽性反応を示した非結核性抗酸菌の2症例, 日本臨床微生物学雑誌, 27, 4, 306-312, 2017.09.
26. Kato Y, Furusyo N, Tanaka Y, Yamasaki S, Ueyama T, Takayama K, Mitsumoto-Kaseida F, Murata M, Ikezaki H, Hayashi J, Association of the Serum Endostatin Level, Renal Function, and Carotid Atherosclerosis of Healthy Residents of Japan: Results from the Kyushu and
Okinawa Population Study (KOPS)., J Atheroscler Thromb., 10.5551, 2018.09.
27. Tanaka Y, Furusyo N, Kato Y, Ueyama T, Yamasaki S, Ikezaki H, Murata M, Hayashi J, Correlation between Thyroid Stimulating Hormone and Renal Function in Euthyroid Residents of Japan: Results from the Kyushu and Okinawa Population Study (KOPS)., J Atheroscler Thromb., 25, 4, 335-343, 2018.04.
28. Ohta A, Furusyo N, Kishihara Y, Eiraku K, Murata M, Kainuma M, Toyoda K, Ogawa E, Hayashi T, Koga T, Secondary Syphilis with Pulmonary Involvement, Intern Med. , 57, 1, 121-126, 2018.01.
29. Ikezaki H, Furusyo N, Jacques PF, Shimizu M, Murata M, Schaefer EJ, Urita Y, Hayashi J, Higher dietary cholesterol and ω-3 fatty acid intakes are associated with a lower success rate of Helicobacter pylori eradication therapy in Japan., Am J Clin Nutr. , 106, 2, 581-588, 2017.08.
30. Ogawa E, Furusyo N, Murata M, Toyoda K, Hayashi T, Ura K, Potential risk of HBV reactivation in patients with resolved HBV infection undergoing direct-acting antiviral treatment for HCV., Liver Int. , 38, 1, 76-83, 2018.01.
31. Tanaka R, Furusyo N, Takeda R, Yamasaki S, Kusaga A, Ogawa E, Murata M, Nakanishi R, Maehara Y, A case of amebiasis with negative serologic markers that caused intra-abdominal abscess., J Infect Chemother. , 23, 11, 778-781, 2017.11.
32. Kato Y, Furusyo N, Tanaka Y, Ueyama T, Yamasaki S, Murata M, Hayashi J, The Relation between Serum Endostatin Level and Carotid Atherosclerosis in Healthy Residents of Japan: Results from the Kyushu and Okinawa Population Study
(KOPS)., J Atheroscler Thromb, 24, 10, 1023-1030, 2017.10.
33. 林 純, 小森 彩佳, 上山 貴嗣, 坂本 篤彦, 小川 栄一, 村田 昌之, 古庄 憲浩, 高齢高血圧患者における推定塩分摂取量 総合診療医としての管理, 12, 1, 33-35, 2017.03.
34. 上山 貴嗣, 武田 倫子, 立石 悠基, 志水 元洋, 居原 毅, 柿本 聖樹, 小川 栄一, 村田 昌之, 平橋 美奈子, 小田 義直, 古庄 憲浩, シスチン尿症を基礎に複雑性尿路感染症からAAアミロイドーシスを合併した一例, 10, 2, 46-49, 2016.06.
35. Fujiko Mitsumoto-Kaseida, Masayuki Murata, Kazuhiro Toyoda, Yuiko Morokuma, Makiko Kiyosuke, DONGCHON KANG, Norihiro Furusyo, Clinical and pathogenic features of SCCmec type II and IV methicillin- resistant Staphylococcus aureus in Japan, JOURNAL OF INFECTION AND CHEMOTHERAPY, 10.1016/j.jiac.2016.11.001, 23, 2, 90-95, 2017.02.
36. Fujiko Mitsumoto-Kaseida, Masayuki Murata, Kazuya Ura, Koji Takayama, Satoshi Hiramine, Motohiro Shimizu, Kazuhiro Toyoda, Eiichi Ogawa, Norihiro Furusyo, The Expression Level of Neutrophil CD64 Is a Useful Marker of Systemic Inflammation Associated with HIV Infection, AIDS RESEARCH AND HUMAN RETROVIRUSES, 10.1089/aid.2016.0107, 33, 2, 147-156, 2017.02.
37. Eiichi Ogawa, Norihiro Furusyo, Masayuki Murata, Motohiro Shimizu, Kazuhiro Toyoda, Taeko Hotta, Takeshi Uchiumi, Jun Hayashi, Comparison of the Abbott RealTime HCV and Roche COBAS Ampliprep/COBAS TaqMan HCV assays for the monitoring of sofosbuvir-based therapy, ANTIVIRAL THERAPY, 10.3851/IMP3085, 22, 1, 61-70, 2016.09.
38. Eri Kumade, Norihiro Furusyo, Norito Takeshima, Yasuhiro Kishihara, Fujiko Mitsumoto-Kaseida, Yoshitaka Eto, Masayuki Murata, Jun Hayashi, A case of lobar pneumonia and sepsis with death caused by invasive Klebsiella rhinoscleromatis infection, J Infect Chemother, 22, 10, 707-711, 2016.10.
39. Motohiro Shimizu, Norihiro Furusyo, Yuki Tanaka, Yoshifumi Kato, Mitsumoto-Kaseida Fujiko, Koji Takayama, Kazuya Ura, Satoshi Hiramine, Takeo Hayashi, Hiroaki Ikezaki, Takeshi Ihara, Haru Mukae, Eiichi Ogawa, Kazuhiro Toyoda, Masayuki Murata, Jun Hayashi, The relation of postprandial plasma glucose and serum endostatin to the urinary albumin excretion of residents with prediabetes: results from the Kyushu and Okinawa Population Study (KOPS), International Urology and Nephrology, 48, 6, 851-857, 2016.06.
40. Takeo Hayashi, Eiichi Ogawa, Norihiro Furusyo, Masayuki Murata, Jun Hayashi, Influence of insulin resistance on the development of hepatocellular carcinoma after antiviral treatment for non-cirrhotic patients with chronic hepatitis C., Infect Agent Cancer, 10.1186/s13027-016-0056-y, 2016.02.
41. Eiichi Ogawa, Norihiro Furusyo, Masayuki Murata, Takeo Hayashi, Motohiro Shimizu, Haru Mukae, Toyoda K, Taeko Hotta, Takeshi Uchiumi, Jun Hayashi, Impact of HCV kinetics on treatment outcome differs by the type of real-time HCV assay in NS3/4A protease inhibitor-based triple therapy, ANTIVIRAL RESEARCH, 10.1016/j.antiviral.2015.12.001, 126, 35-42, 2016.02.
42. Hiroaki Ikezaki, Norihiro Furusyo, Satoshi Hiramine, Kazuya Ura, Fujiko Mitsumoto-Kaseida, Koji Takayama, Motohiro Shimizu, Toyoda K, Eiichi Ogawa, M KAINUMA, Masayuki Murata, Jun Hayashi, Association of IL28B rs8099917 genotype and female sex with spontaneous clearance of hepatitis C virus infection: a Japanese cross-sectional study, ARCHIVES OF VIROLOGY, 10.1007/s00705-015-2703-9, 161, 3, 641-648, 2016.03.
43. Kazuya Ura, Norihiro Furusyo, Eiichi Ogawa, Takeo Hayashi, Haru Mukae, Motohiro Shimizu, Toyoda K, Masayuki Murata, Jun Hayashi, Serum WFA(+) -M2BP is a non-invasive liver fibrosis marker that can predict the efficacy of direct-acting anti-viral-based triple therapy for chronic hepatitis C, Alimentary Pharmacology and Therapeutics, 43, 1, 114-124, 2016.01.
44. Koji Takayama, Norihiro Furusyo, Eiichi Ogawa, Hiroaki Ikezaki, Motohiro Shimizu, Masayuki Murata, Jun Hayashi, Direct-acting antiviral-based triple therapy on alpha-fetoprotein level in chronic hepatitis C patients, WORLD JOURNAL OF GASTROENTEROLOGY, 10.3748/wjg.v21.i15.4696, 21, 15, 4696-4706, 2015.04.
45. Hiroaki Ikezaki, Norihiro Furusyo, Takeshi Ihara, Takeo Hayashi, Kazuya Ura, Satoshi Hiramine, Fujiko Mitsumoto, Koji Takayama, Masayuki Murata, Takuji Kohzuma, Masumi Ai, Emst J. Schaefer, Jun Hayashi, Glycated albumin as a diagnostic tool for diabetes in a general Japanese population, METABOLISM-CLINICAL AND EXPERIMENTAL, 10.1016/j.metabol.2015.03.003, 64, 6, 698-705, 2015.06.
46. Fujiko Mitsumoto, Masayuki Murata, kazuya Ura, Koji Takayama, Satoshi Hiramine, Motohiro Shimizu, Toyoda K, Eiichi Ogawa, Norihiro Furusyo, Jun Hayashi, The kinetics of the hepatitis B surface antigen level after the initiation of antiretroviral therapy for hepatitis B virus and human immunodeficiency virus coinfected patients, JOURNAL OF INFECTION AND CHEMOTHERAPY, 10.1016/j.jiac.2014.12.003, 21, 3-4, 264-271, 2015.04.
47. 加藤 禎史, 古庄 憲浩, 志水 元洋, 小川 栄一, 山嵜 奨, 迎 はる, 豊田 一弘, 貝沼 茂三郎, 村田 昌之, 林 純, 右上腕リンパ節膿瘍を形成し外科的処置を要した猫ひっかき病の一例, 6, 1, 28-31, 2014.04.
48. 小森 彩佳, 岡田 享子, 大西 八郎, 小川 栄一, 豊田 一弘, 貝沼 茂三郎, 村田 昌之, 古庄 憲浩, 林 純, バセドウ病に対して甲状腺全摘術10年後に緩徐進行1型糖尿病を発症した多腺性自己免疫症候群III型の1例, 6, 1, 16-19, 2014.04.
49. 佐藤 憲仁, 古庄 憲浩, 光本 富士子, 田中 佑樹, 畑島 梓, 小川 栄一, 豊田 一弘, 村田 昌之, 大石 善丈, 小田 義直, 林 純, 腹腔鏡下腹膜生検で判明した腹膜悪性中皮腫の一例, 6, 2, 66-71, 2014.06.
50. 畑島 梓, 古庄 憲浩, 加藤 禎史, 原田 裕士, 大西 八郎, 小川 栄一, 豊田 一弘, 村田 昌之, 林 純, 慢性活動性EBウイルス感染症の関与が考えられた肝脾T細胞性リンパ腫の一例, 6, 2, 55-60, 2014.06.
51. 志水 元洋, 村田 昌之, 光本 富士子, 迎 はる, 小川 栄一, 豊田 一弘, 岡田 享子, 貝沼 茂三郎, 江藤 義隆, 古庄 憲浩, 林 純, 市中感染型MRSAにより生じた化膿性脊椎炎の1例, 30, 5, 805-811, 2014.04.
52. 迎 はる, 古庄 憲浩, 村田 昌之, 小川 栄一, 貝沼 茂三郎, 志水 元洋, 居原 毅, 林 純, A case of granulomatosis with polyangiitis preceded by subacute thyroiditis., 10.1002/ccr3.181., 3, 3, 139-144, 2015.03.
53. 志水 元洋, 古庄 憲浩, 池崎 裕昭, 小川 栄一, 林 武生, 居原 毅, 原田 裕士, 豊田 一弘, 村田 昌之, 林 純, Predictors of kidney tubular dysfunction induced by adefovir treatment for
chronic hepatitis B., 10.3748/wjg.v21.i7.2116., 21, 7, 2116-2123, 2015.02.
54. 志水 元洋, 古庄 憲浩, 光本 富士子, 高山 耕治, 浦 和也, 平峯 智, 池崎 裕昭, 居原 毅, 迎 はる, 小川 栄一, 豊田 一弘, 貝沼 茂三郎, 村田 昌之, 林 純, Subclinical carotid atherosclerosis and triglycerides predict the incidence of
chronic kidney disease in the Japanese general population: results from the
Kyushu and Okinawa Population Study (KOPS)., 238, 2, 207-212, 2015.02.
55. 光本 富士子, 村田 昌之, 加藤 禎史, 浦 和也, 高山 耕治, 平峯 智, 池崎 裕昭, 志水 元洋, 豊田 一弘, 小川 栄一, 相島 慎一, 古庄 憲浩, 林 純, Hepatitis B virus-related immune reconstitution inflammatory syndrome in two
patients coinfected with human immunodeficiency virus diagnosed with a liver
biopsy., 53, 18, 2165-2170, 2014.09.
56. 高山 耕治, 古庄 憲浩, 小川 栄一, 志水 元洋, 平峯 智, 光本 富士子, 浦 和也, 豊田 一弘, 村田 昌之, 林 純, A case of successful treatment with telaprevir-based triple therapy for hepatitis
C infection after treatment failure with vaniprevir-based triple therapy., 10.1016/j.jiac.2014.06.002, 20, 9, 577-581, 2014.09.
57. 貝沼 茂三郎, 古庄 憲浩, 安藤 眞一, 迎 はる, 小川 栄一, 豊田 一弘, 村田 昌之, 林 純, Nocturnal difference in the ultra low frequency band of heart rate variability in
patients stratified by Kampo medicine prescription., 78, 8, 1924-1927, 2014.06.
58. 村田 昌之, 古庄 憲浩, 小川 栄一, 光本 富士子, 平峯 智, 池崎 裕昭, 高山 耕治, 志水 元洋, 豊田 一弘, 貝沼 茂三郎, 林 純, A case of successful hepatitis C virus eradication by 24 weeks of
telaprevir-based triple therapy for a hemophilia patient with hepatitis C
virus/human immunodeficiency virus co-infection who previously failed pegylated
interferon-α and ribavirin therapy, 10.1016/j.jiac.2013.11.006., 20, 5, 320-324, 2014.05.
59. 村田 昌之, 古庄 憲浩, 柳澤 昊永, 林 純, ナノ型乳酸菌Enterococcus faecalis (nEC)含有ガムとグミ摂取によるヒトへの安全性および免疫調節作用に関する検討, 91, 4, 125-130, 2014.04.
60. 古庄 憲浩, 小川 栄一, 村田 昌之, 豊田 一弘, 大西 八郎, 永樂 訓三, 志水 元洋, 原田 裕士, 光本 富士子, 高山 耕治, 貝沼 茂三郎, 岡田 享子, 林 純, Therapeutic drug monitoring of telaprevir in chronic hepatitis C patients receiving telaprevir-based triple therapy is useful for predicting virological
response., 10.1093/jac/dkt371., 2014.02.
61. 光本 富士子, 村田 昌之, 加藤 禎史, 浦 和也, 高山 耕治, 平峯 智, 池崎 裕昭, 志水 元洋, 豊田 一弘, 小川 栄一, 相島 慎一, 古庄 憲浩, 林 純, Hepatitis B virus related immune reconstitution inflammatory syndrome, undergone liver biopsy, in two patients coinfected with human immunodeficiency virus, 2014.01.
62. 居原 毅, 古庄 憲浩, 林 武生, 豊田 一弘, 村田 昌之, 林 純, A population-based epidemiological survey of human parvovirus B19 infection: a
project of the Kyushu and Okinawa Population Study (KOPS)., 10.1007/s00705-013-1746-z., 2013.12.
63. 小川 栄一, 古庄 憲浩, 村田 昌之, 池崎 裕昭, 居原 毅, 林 武生, 豊田 一弘, 岡田 享子, 貝沼 茂三郎, 梶原 英二, 高橋 和弘, 佐藤 丈顕, 林 純, Valuable antiviral therapeutic options for the treatment of chronic hepatitis C
patients with thrombocytopenia., 10.1111/jvh.12109., 2013.12, Thrombocytopenia in patients with chronic hepatitis C may represent an obstacle
for the initiation of antiviral treatment. The aim of this study was to evaluate
factors predictive of successful pegylated interferon (PEG-IFN) α2b and ribavirin
(RBV) treatment for patients with thrombocytopenia with no history of splenectomy
or partial splenic embolization. One hundred and fifty-one chronic hepatitis C
patients (genotype 1: n = 110, genotype 2: n = 41) with TCP (baseline were enrolled. Pretreatment variables included interleukin 28B (IL28B)
genotype (rs8099917) and homoeostasis model assessment of insulin resistance
score (HOMA-IR). The kinetics of haemoglobin and platelets according to the
inosine triphosphatase (ITPA) genotype (rs1127354) were investigated. Sustained
virological response (SVR) was significantly more frequent in hepatitis C virus
(HCV) genotype 2 (65.9%) than in genotype 1 (34.5%) patients (P Multiple logistic regression analysis of HCV genotype 1 extracted IL28B TT
genotype [odds ratio (OR) 5.97, P = 0.006] and HOMA-IR as significant independent pretreatment predictors of SVR. The analyses of HCV
genotype 2 showed that HOMA-IR was significantly related to SVR, but IL28B
genotype was not. Patients with ITPA CC genotype showed a significant haemoglobin
reduction and lower degree of platelets decrease than those with ITPA CA/AA
genotypes. The most common reason for premature discontinuation of treatment was
the development of hepatocellular carcinoma (n = 8, 5.3%). In conclusion, HOMA-IR
is a useful predictor of SVR for patients with thrombocytopenia infected with HCV
genotype 1 or 2 treated with PEG-IFNα2b and RBV. The inclusion of IL28B, ITPA
genotypes and HOMA-IR adds valuable therapeutic information..
64. 村田 昌之, 古庄 憲浩, 小川 栄一, 光本 富士子, 平峯 智, 池崎 裕昭, 高山 耕治, 志水 元洋, 豊田 一弘, 貝沼 茂三郎, 林 純, A case of successful hepatitis C virus eradication by 24 weeks of telaprevir-based triple therapy for a hemophilia patient with hepatitis C virus/human immunodeficiency virus co-infection who previously failed pegylated interferon-α and ribavirin therapy., doi: 10.1016/j.jiac.2013.11.006., 2013.11, In Japan, the human immunodeficiency virus (HIV) and hepatitis C virus (HCV)
coinfection of some patients with hemophilia was caused by the transfusion of
imported blood products, such as unheated coagulation factor. With the
development of antiretroviral therapy (ART) for HIV, chronic HCV infection has
become a major cause of liver disease and mortality for hemophiliac patients
coinfected with HCV/HIV. Data is limited regarding the efficacy and safety of
antiviral therapy with the HCV protease inhibitor telaprevir (TVR) in combination
with pegylated interferon-α (PegIFN-α) and ribavirin (RBV) for hemophilia
patients coinfected with HCV/HIV. We report a case of a Japanese patient with
hemophilia and HCV/HIV coinfection who had partial response to prior to PegIFN-α
and RBV therapy. This is the first published report of 24-week TVR-based triple
therapy for a hemophilia patient coinfected with HCV/HIV. The patient had HCV
genotype 1a infection with a high viral load. His single-nucleotide polymorphism
of the interleukin 28B (rs8099917) gene was the TT major allele. He presented
with undetectable HIV RNA and a high CD4(+) T cell counts by taking ART including
tenofovir, emtricitabine and raltegravir. He was again treated for HCV with TVR
plus PegIFN-α2b and RBV for the first 12 weeks, followed by the continuation of
PegIFN-α2b and RBV for 12 additional weeks while continuing ART. He had rapid
virological response and achieved sustained virological response with the 24-week
treatment. No serious adverse events such as skin rash, severe anemia or
exacerbated bleeding tendency were observed, only a mild headache. No dose
adjustment was necessary when tenofovir and raltegravir were used in combined
with TVR, and no HIV breakthrough was observed. TVR-based triple therapy with ART
could can an effective treatment for hemophilia patients coinfected with HCV
(genotype 1)/HIV regardless of prior response. TVR can be used in combination
with tenofovir, emtricitabine and raltegravir for patients with hemophilia.
Furthermore, patients with undetectable HCV RNA at week 4 could be successfully
treated with a 24-week regimen..
65. 早崎 咲子, 岡田 享子, 貝沼 茂三郎, 池崎 裕昭, 林 武生, 居原 毅, 永樂 訓三, 小川 栄一, 谷合 啓明, 村田 昌之, 古庄 憲浩, 林 純, 当科で経験した菊池病について, 5, 1, 5-9, 2013.09.
66. 加藤 禎史, 古庄 憲浩, 光本 富士子, 村田 昌之, 小川 栄一, 豊田 一弘, 新野 大介, 大島 孝一, 林 純, 不明熱と全身リンパ節腫大が発見の契機となった加齢性Epstein-Barr Virus関連リンパ増殖異常症の一例, 5, 1, 10-14, 2013.09.
67. 高山 耕治, 古庄 憲浩, 岡田 享子, 大西 八郎, 豊田 一弘, 小川 栄一, 貝沼 茂三郎, 村田 昌之, 林 純, 急性心筋梗塞を契機に発見された緩徐進行1型糖尿病(SPIDDM)の一例, 5, 1, 15-18, 2013.09.
68. 小川 栄一, 古庄 憲浩, 村田 昌之, 豊田 一弘, 永樂 訓三, 志水 元洋, 原田 裕士, 光本 富士子, 高山 耕治, 岡田 享子, 貝沼 茂三郎, 林 純, Early phase viral kinetics of chronic hepatitis C patients receiving
telaprevir-based triple therapy: a comparison of two real-time PCR assays., 10.1016/j.antiviral.2013.05.002., 2013.08.
69. 谷合 啓明, 古庄 憲浩, 村田 昌之, 光本 富士子, 志水 元洋, 豊田 一弘, 小川 栄一, 貝沼 茂三郎, 岡田 享子, 林 純, A case report of human immunodeficiency virus-associated anaplastic lymphoma
kinase protein-negative anaplastic large cell lymphoma., 10.1186/2193-1801-2-400, 2013.08, Human immunodeficiency virus (HIV)-associated anaplastic large cell lymphoma
(ALCL) is not so common, and anaplastic lymphoma kinase protein (ALK)-negative
ALCL is rare and has a low survival rate. We report a case of a 31-year-old
Japanese man diagnosed with HIV-associated ALK-negative ALCL who presented with
long-lasting fever of unknown origin. The diagnosis was based on a full work-up
that included inguinal lymph-node biopsy. Eight-cycle chemotherapy that included
cyclophosphamide, doxorubicin, vincristine, and prednisone in addition to
antiretroviral therapy for HIV infection provided a complete remission of his
ALCL and over 5-year survival for him..
70. 古庄 憲浩, 小川 栄一, 村田 昌之, 林 純, C型慢性肝炎合併の閉経後骨粗鬆症に対する塩酸ラロキシフェンの骨への効果と安全性 ペグインターフェロンα2a、リバビリン併用治療中において, 90, 6, 843-845, 2013.06.
71. 加藤 禎史, 古庄 憲浩, 村田 昌之, 小川 栄一, 光本 富士子, 熊手 絵璃, 谷合 啓明, 豊田 一弘, 林 純, 気胸を呈したAIDS合併ニューモシスチス肺炎の一例, 4, 2, 45-49, 2013.06.
72. 畑島 梓, 古庄 憲浩, 光本 富士子, 小川 栄一, 豊田 一弘, 谷合 啓明, 貝沼 茂三郎, 岡田 享子, 村田 昌之, 林 純, 高齢男性に発症した全身性エリテマトーデスの1例, 4, 2, 50-54, 2013.06.
73. 山嵜 奨, 古庄 憲浩, 小川 栄一, 酒見 倫子, 熊手 絵璃, 豊田 一弘, 谷合 啓明, 岡田 享子, 貝沼 茂三郎, 村田 昌之, 林 純, 頸部リンパ節切除後に改善したCastleman病の一例, 4, 2, 55-59, 2013.06.
74. 古庄 憲浩, 居原 毅, 林 武生, 池崎 裕昭, 豊田 一弘, 小川 栄一, 岡田 享子, 貝沼 茂三郎, 村田 昌之, 林 純, The serum undercarboxylated osteocalcin level and the diet of a Japanese
population: results from the Kyushu and Okinawa Population Study (KOPS)., 10.1007/s12020-012-9803-z, 2013.06.
75. 熊手 絵璃, 古庄 憲浩, 光本 富士子, 小川 栄一, 豊田 一弘, 貝沼 茂三郎, 村田 昌之, 林 純, 長期のアデホビル投与によりFanconi症候群を来したB型慢性肝炎の1例, 54, 3, 187-193, 2013.03.
76. Walaa H Ahmed, 古庄 憲浩, Saad Zaky, Abeer Sharaf Eldin, Hany Aboalam, 小川 栄一, 村田 昌之, 林 純, Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for
predicting anemia in Egyptian hepatitis C virus patients., 10.3748/wjg.v19.i9.1387., 2013.03.
77. 岡田 享子, 古庄 憲浩, 小川 栄一, 池崎 裕昭, 居原 毅, 林 武生, 貝沼 茂三郎, 村田 昌之, 林 純, Association between chronic hepatitis C virus infection and high levels of
circulating N-terminal pro-brain natriuretic peptide., 10.1007/s12020-012-9688-x., 2013.02.
78. 林 純, 下野 信行, 古庄 憲浩, 村田 昌之, 保科 隆之, 豊田 一弘, 青木 知信, 井口 厚司, 宮崎 正之, 髙田 徹, 岡田 賢司, 田尾 善昭, 内田 勇二郎, 近藤 浩子, 田邊 雄一, 院内感染対策に対する多施設集団教育の効果, 89, 11, 1561-1568, 2012.12.
79. 安河内 由美, 古庄 憲浩, 豊田 一弘, 谷合 啓明, 小川 栄一, 貝沼 茂三郎, 岡田 享子, 村田 昌之, 丸山 治彦, 林 純, ウエステルマン肺吸虫症の臨床 当科で経験した4症例より, 3, 2, 65-70, 2012.12.
80. 古庄 憲浩, 小川 栄一, 須藤 正幸, 村田 昌之, 居原 毅, 池崎 裕昭, 平峯 智, 迎 はる, 豊田 一弘, 谷合 啓明, 岡田 享子, 貝沼 茂三郎, 梶原 英二, 林 純, Raloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal
women with chronic hepatitis C: a randomized trial., 10.1016/j.jhep.2012.08.003, 2012.12.
81. 光本 富士子, 村田 昌之, 池崎 裕昭, 小川 栄一, 谷合 啓明, 豊田 一弘, 大田黒 滋, 貝沼 茂三郎, 岡田 享子, 古庄 憲浩, 林 純, A case of hepatitis B virus/human immunodeficiency virus coinfection in a
patient who achived hepatitis B surface antigen seroclearance after interferon
therapy followed by antiretroviral therapy without developing immune
reconstitution inflammatory syndrome, 86, 6, 763-767, 2012.11, Coinfection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV)
is common worldwide. The current guidelines for the treatment of HIV infection
recommend that HIV patients coinfected with HBV receive antiretoroviral therapy
(ART) with two nucleoside analogs against HBV. However, an increase in liver
enzymes that is usually attributed to HBV immune reconstitution inflammatory
syndrome (IRIS) sometimes occurs in HBV/HIV-coinfected patients after the
commencement of ART. We report a case of HBV/HIV-coinfection in which the chronic
hepatitis B was successfully treated using interferon (IFN) therapy followed by
ART without the development of IRIS. A Japanese man in thirties was referred to
our hospital because of an acute HIV infection two months after the diagnosis of
an acute HBV infection, which had progressed to a chronic HBV infection. The
laboratory test results were as follows:hepatitis B surface antigen (HBsAg)
positive, hepatitis B e antigen (HBeAg) positive, HBV DNA level of 8.8 Log
copies/mL, HBV genotype A, alanine aminotransferase of 834 IU/L, HIV RNA level of
5 Log copies/mL, and a CD4+ T cell count of 437/microL. The initial treatment was
natural IFNalpha therapy for chronic hepatitis B, and HBeAg seroclearance was
achieved 20 weeks after the start of therapy. Four months after the end of IFN
therapy for 24 weeks, ART including tenofovir and emtricitabine against HBV was
commenced. Six months after starting ART, the patient's serum HBV DNA level had
decreased and become undetectable and HBsAg seroclearance was achieved without an
elevation in liver enzymes. The present case suggests that IFN therapy prior to
ART contributes to a successful outcome for chronic hepatitis B patients
coinfected with HIV, if the HIV status does not require the immediate start of
ART..
82. 小川 栄一, 古庄 憲浩, 村田 昌之, 池崎 裕昭, 居原 毅, 林 武生, 豊田 一弘, 谷合 啓明, 岡田 享子, 貝沼 茂三郎, 林 純, Insulin resistance undermines the advantages of IL28B polymorphism in the
pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C
patients with genotype 1., 10.1016/j.jhep.2012.04.027, 2012.09.
83. 池崎 裕昭, 古庄 憲浩, 大田黒 滋, 居原 毅, 小川 栄一, 豊田 一弘, 谷合 啓明, 貝沼 茂三郎, 岡田 享子, 村田 昌之, 澤山 泰典, 林 純, 骨髄不全症候群を基礎とした輸血歴のない続発性ヘモクロマトーシスの1例, 89, 5, 654-658, 2012.05.
84. 平峯 智, 村田 昌之, 酒見 倫子, 大西 八郎, 小川 栄一, 谷合 啓明, 長崎 洋司, 古庄 憲浩, 林 純, An AIDS patient with adrenal crisis after immune reconstitution
inflammatory syndrome due to Pneumocystis jiroveci pneumonia, 101, 5, 1389-1392, 2012.05.
85. 平峯 智, 村田 昌之, 大西 八郎, 小川 栄一, 谷合 啓明, 古庄 憲浩, 林 純, 早期のART導入が奏功したHIV合併重症化B型急性肝炎(genotype A)の1例, 3, 2, 76-80, 2012.02.
86. 岡田 享子, 古庄 憲浩, 村田 昌之, 澤山 泰典, 貝沼 茂三郎, 林 純, A hypertriglyceridemic state increases high sensitivity C-reactive protein of
Japanese men with normal glucose tolerance., 10.1007/s12020-011-9532-8, 2012.02.
87. 池崎 裕昭, 古庄 憲浩, 居原 毅, 林 武生, 小川 栄一, 豊田 一弘, 谷合 啓明, 貝沼 茂三郎, 村田 昌之, 林 純, Abbott RealTime PCR assay is useful for evaluating virological response to
antiviral treatment for chronic hepatitis C., 10.1007/s10156-011-0249-7, 2011.12.
88. 小川 栄一, 古庄 憲浩, 村田 昌之, 大西 八郎, 豊田 一弘, 谷合 啓明, 居原 毅, 池崎 裕昭, 林 武生, 貝沼 茂三郎, 林 純, Longitudinal assessment of liver stiffness by transient elastography for chronic
hepatitis B patients treated with nucleoside analog., 10.1111/j.1872-034X.2011.00869.x, 2011.12.
89. 古庄 憲浩, Walaa H Ahmed, 永樂 訓三, 豊田 一弘, 小川 栄一, 池崎 裕昭, 居原 毅, 林 武生, 貝沼 茂三郎, 村田 昌之, 林 純, Treatment for Eradication of Helicobacter pylori Infection among Chronic
Hepatitis C Patients., 10.5009/gnl.2011.5.4.447, 2011.12.
90. 廣岡 さとみ, 井浦 とも, 野田 和人, 山田 猛, 村田 昌之, 急性HIV感染症に合併した非典型的Guillain-Barre症候群の1例, 75, 5, 515-517, 2011.11.
91. 平峯 智, 古庄 憲浩, 小川 栄一, 豊田 一弘, 谷合 啓明, 村田 昌之, 林 純, クォンティフェロンTB-2G法および腹腔鏡下腹膜生検により診断した東アフリカ人男性の結核性腹膜炎の一例, 2, 1, 27-33, 2011.10.
92. 林 武生, 貝沼 茂三郎, 谷合 啓明, 村田 昌之, 岡田 享子, 澤山 泰典, 古庄 憲浩, 林 純, 天然型IFNα少量長期投与療法による1型糖尿病発症が疑われたC型慢性肝炎の1例, 52, 6, 335-343, 2011.06.
93. Murata M, Furusyo N, Unno M, Ogawa E, Toyoda K, Taniai H, Ohnishi H, Hayashi J., Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients., World J Gastroenterol. 2011 Jun 28;17(24):2945-52., 17, 24, 2945-52, 2011.06, AIM:
To analyze the association between the emergence of tyrosine-methionine-asparatate-asparatate (YMDD) mutants (reverse transcription; rtM204I/V) and deterioration of liver function during long-term lamivudine treatment of Japanese patients with chronic hepatitis B virus (HBV) infection.
METHODS:
The data of 61 consecutive Japanese patients with chronic hepatitis B who underwent continuous lamivudine treatment for more than 24 mo and had a virological response were analyzed. Analysis of YMDD mutants was done by real-time polymerase chain reaction with LightCycler probe hybridization assay for up to 90 mo (mean, 50.8 mo; range, 24-90 mo).
RESULTS:
A mixed mutant-type (YMDD + tyrosine-isoleucine-asparatate-asparatate: YIDD or tyrosine-valine-asparatate-asparatate: YVDD) or a mutant-type (YIDD or YVDD) were found in 57.4% of 61 patients at 1 year, 78.7% of 61 patients at 2 years, 79.6% of 49 patients at 3 years, 70.5% of 34 patients at 4 years, 68.4% of 19 patients at 5 years, 57.1% of 14 patients at 6 years, and 33.3% of 6 patients at 7 years. Of the 61 patients, 56 (92%) had mixed mutant- or a mutant-type. Only 5 (8%) had no mutants at each observation point. Virological breakthrough was found in 26 (46.4%) of 56 patients with YMDD mutants, 20 of whom had a hepatitis flare-up: the remaining 30 (53.6%) had neither a virological breakthrough nor a flare-up. All 20 patients who developed a hepatitis flare-up had a biochemical and virological response after adefovir was added to the lamivudine treatment.
CONCLUSION:
Our results suggest that it is possible to continue lamivudine treatment, even after the emergence of YMDD mutants, up to the time that the patients develop a hepatitis flare-up..
94. 貝沼 茂三郎, 迎 はる, 古庄 憲浩, 海野 麻美, 白土 基明, 村田 昌之, 林 純, 骨髄異形成症候群による貧血・血小板減少に十全大補湯加膠飴が奏効した1例, 62, 3, 363-368, 2011.05.
95. 古庄 憲浩, 村田 昌之, 小川 栄一, 豊田 一弘, 居原 毅, 池崎 裕昭, 林 武生, 古賀 恒久, 貝沼 茂三郎, 林 純, Ribavirin concentration in the later stages of 48 week pegylated
interferon-alpha2b plus ribavirin therapy for chronic hepatitis C is useful for
predicting virological response., 10.1093/jac/dkr034, 2011.05.
96. 小川 栄一, 村田 昌之, 池崎 裕昭, 居原 毅, 高山 耕治, 豊田 一弘, 貝沼 茂三郎, 澤山 泰典, 古庄 憲浩, 江崎 幹宏, 松本 主之, 後藤 綾子, 山元 英崇, 林 純, 【免疫不全状態における消化管病変】 消化管Kaposi肉腫を合併したHIV感染症の2例, 46, 3, 303-309, 2011.03.
97. 池崎 裕昭, 小川 栄一, 村田 昌之, 居原 毅, 豊田 一弘, 谷合 啓明, 大田黒 滋, 貝沼 茂三郎, 澤山 泰典, 古庄 憲浩, 林 純, A case of AIDS-associated Kaposi's sarcoma with systemic invasion, 85, 1, 54-58, 2011.01.
98. Masayuki Murata, Norihiro Furusyo, Yayoi Fujimoto, Yoko Kanamoto, Shigeru Otaguro, Eiichi Ogawa, Ryo Yasuhara, Naoko Yamamoto, Jun Hayashi., Evaluation of a New Desktop Washer-Disinfector for the Viral Disinfection of Medical Devices., Japanese Journal of Environmental Infections, 22; 118-21, 2007.06.
99. Murata M, Furusyo N, Otaguro S, Nabeshima S, Ariyama I, Hayashi J, HIV Infection with Concomitant Cerebral Toxoplasmosis and Disseminated Histoplasmosis in a 45-Year-Old Man., J Infect Chemother, 13:51-5, 2007.03.
100. Murata M, Nabeshima S, Kikuchi K, Yamaji K, Furusyo N, Hayashi J, A comparison of the antitumor effects of interferon-alpha and beta on human hepatocellular carcinoma cell lines., Cytokine, 33:121-8, 2006.02.
101. Murata M, Kishihara Y, Nabeshima S, Furusyo N, Kuroki M, Hayashi J, Evaluation of a new ozone apparatus, the BOX-O3, for the bacteriological disinfection of medical waste., Japanese society of environmental infections, Vol.19 no.2, 277-80, 2004.01.
102. Murata M, Nabeshima S, Maeda N, Nakashima H, Kashiwagi S & Hayashi J., Increased frequency of IFN-g-producing peripheral CD8+ T cells with memory-phenotype in patients with chronic hepatitis C., Journal of medical virology, 10.1002/jmv.2205, 67, 2, 162-170, 67(2):162-70, 2002.01.

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pure2017年10月2日から、「九州大学研究者情報」を補完するデータベースとして、Elsevier社の「Pure」による研究業績の公開を開始しました。