Updated on 2025/06/11

Information

 

写真a

 
ISHIHARA TAKESHI
 
Organization
Faculty of Science Department of Biology Professor
Material Management Center （Concurrent）
School of Sciences Department of Biology（Concurrent）
Graduate School of Systems Life Sciences Department of Systems Life Sciences（Concurrent）
Title
Professor
Contact information
メールアドレス
Profile
Animals sense many environmental stimuli and, by responding to them, they behave properly. We are interested in mechanisms on sensory processing in neuronal circuits which regulates behavior. We use C. elegans as a model organism to elucidate molecular mechanisms of informational processing. I give lectures on basic molecular genetics and molecular biology for under graduate student. In addition for members in our lab, I have earnest discussions not only on their students studies but also on the logic and methodology of biological science.
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Research Areas

  • Life Science / Molecular biology

  • Life Science / Neuroscience-general

Degree

  • Ph.D （ 1992.3 The University of Tokyo ）

Research History

  • Kyushu University 理学研究院 Professor 

    2004.4 - Present

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    Country：Japan

  • 九州大学 大学院・理学研究院  Professor 

    2004 - Present

  • National Institute of Genetics  Research Assistant 

    1992.4 - 2004.3

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    Country：Japan

  • 日本学術振興会特別研究員   

    1991.3 - 1992.4

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    Country：Japan

Education

  • The University of Tokyo   理学系研究科   生物化学専攻

    1986.4 - 1992.3

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    Country：Japan

  • The University of Tokyo   理学部   生物化学科

    1982.4 - 1986.3

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    Country：Japan

Research Interests・Research Keywords

  • Research theme： 情報処理

    Keyword： 情報処理

    Research period： 2025

  • Research theme： 学習

    Keyword： 学習

    Research period： 2025

  • Research theme： カルシウムイオン

    Keyword： カルシウムイオン

    Research period： 2025

  • Research theme： C.elegans

    Keyword： C.elegans

    Research period： 2025

  • Research theme： Studies on sensory processing in C. elegans

    Keyword： behavior, brain, neuronal plasticity, C. elegans, genetics

    Research period： 2000.1 - 2032.12

Papers

  • Mechanism of sensory perception unveiled by simultaneous measurement of membrane voltage and intracellular calcium. Reviewed

    Tokunaga T, Sato N, Arai M, Nakamura T, Ishihara T.

    Communications Biology   7 ( 1 )   1150   2024.9

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    生きている線虫を無侵襲条件で、刺激に依存した膜電位と細胞内カルシウム変化を同時高速にイメージング解析し、その発生の分子メカニズムを明らかにするとともにそれぞれがコードする情報の違いを明らかにした。

    DOI： 10.1038/s42003-024-06778-2.

  • Regulation of Diacylglycerol Content in Olfactory Neurons Determines Forgetting or Retrieval of Olfactory Memory in Caenorhabditis elegans Invited Reviewed International journal

    Mary Arai, Itsuki Kurokawa, Hoshinosuke Arakane, Tomohiro Kitazono, Takeshi Ishihara

    JOURNAL OF NEUROSCIENCE   42 ( 43 )   8039 - 8053   2022.10   （ ISSN:0270-6474 eISSN:1529-2401 ）

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Journal of Neuroscience  

    Proper management of memories by forgetting and retrieval is essential for animals to adapt their behavior to changing environments. To elucidate the mechanisms underlying forgetting, we use olfactory learning to an attractive odorant, diacetyl, in Caenorhabditis elegans hermaphrodites as a model. In this learning paradigm, the TIR-1/JNK-1 pathway in AWC sensory neurons accelerates forgetting of the olfactory memory, which is stored as a sensory memory trace in AWA sensory neurons. Our genetic screening revealed that increased neuronal diacylglycerol in the olfactory neuronal circuit, by mutations in diacylglycerol kinase-1, egl-30 or goa-1, Gq and Go type G-proteins, suppresses the forgetting defect in the behavior of tir-1 mutants, although the calcium imaging analyses of the olfactory neurons revealed that the sensory memory trace to the odorant was maintained. In contrast, the expression of a gain-of-function goa-1 gene exclusively in AWC neurons caused a forgetting defect in behavior, although their sensory memory trace declined. Furthermore, the behavioral analysis of animals applied with diacylglycerol analog and measurement of diacylglycerol content by fluorescent imaging suggested that diacylglycerol content in AWC is important for the proper forgetting. These findings raise a possibility that diacylglycerol signaling plays a crucial role in determining whether to forget or to recall in olfactory learning.SIGNIFICANCE STATEMENT Forgetting and retrieval are important processes for proper management of memories, although the mechanisms underlying these processes remain largely unclear. We found that, in Caenorhabditis elegans, diacylglycerol signaling works in a forgetting mechanism downstream of TIR-1/JNK-1 pathway. Mutations that change diacylglycerol content in the olfactory neurons affect behavioral forgetting, although they did not alter the sensory memory trace. This suggests that diacylglycerol in specific neurons may determine the occurrence of retrieving, rather than modifying, the memory traces. Consistent with this hypothesis, application of diacylglycerol analog to animals suggests that diacylglycerol content until memory acquisition decides whether to retrieve or to forget the memory.

    DOI： 10.1523/JNEUROSCI.0090-22.2022

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  • Behavioral Forgetting of Olfactory Learning Is Mediated by Interneuron-Regulated Network Plasticity in Caenorhabditis elegans Invited Reviewed International journal

    #Teo Jamine Hooi-Min, #Kurokawa Itsuki, #Onishi Yuuki, @Sato Noriko, #Kitazono Tomohiro, Tokunaga Terumasa, @Fujiwara Manabi, #Ishihara Takeshi

    ENEURO   9 ( 4 )   ENEURO.0084 - 22.2022   2022.7   （ eISSN:2373-2822 ）

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Society for Neuroscience  

    Forgetting is important for animals to manage acquired memories to enable adaptation to changing environments; however, the neural network in mechanisms of forgetting is not fully understood. To understand the mechanisms underlying forgetting, we examined olfactory adaptation, a form of associative learning, in Caenorhabditis elegans. The forgetting of diacetyl olfactory adaptation in C. elegans is regulated by secreted signals from AWC sensory neurons via the TIR-1/JNK-1 pathway. These signals cause a decline of the sensory memory trace in AWA neurons, where diacetyl is mainly sensed. To further understand the neural network that regulates this forgetting, we investigated the function of interneurons downstream of AWA and AWC neurons. We found that a pair of interneurons, AIA, is indis-pensable for the proper regulation of behavioral forgetting of diacetyl olfactory adaptation. Loss or inactivation of AIA caused the impairment of the chemotaxis recovery after adaptation without causing severe chemotaxis defects in the naive animal. AWA Ca2+ imaging analyses suggested that loss or inactivation of AIA interneurons did not affect the decline of the sensory memory trace after the recovery. Furthermore, AIA responses to diacetyl were observed in naive animals and after the recovery, but not just after the conditioning, suggesting that AIA responses after the recovery are required for the chemotaxis to diacetyl. We propose that the functional neuronal circuit for attractive chemo-taxis to diacetyl is changed temporally at the recovery phase so that AIA interneurons are required for chemotaxis, although AIAs are dispensable for attractive chemotaxis to diacetyl in naive animals.

    DOI： 10.1523/ENEURO.0084-22.2022

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  • Multiple signaling pathways coordinately regulate forgetting of olfactory adaptation through control of sensory responses in caenorhabditis elegans Reviewed International journal

    Tomohiro Kitazono, Sayuri Hara-Kuge, Osamu Matsuda, Akitoshi Inoue, Manabi Fujiwara, Takeshi Ishihara

    Journal of Neuroscience   37 ( 42 )   10240 - 10251   2017.10

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    Language：English   Publishing type：Research paper (scientific journal)  

    Forgetting memories is important for animals to properly respond to continuously changing environments. To elucidate the mechanisms of forgetting, we used one of the behavioral plasticities of Caenorhabditis elegans hermaphrodite, olfactory adaptation to an attractive odorant, diacetyl, as a simple model of learning. In C. elegans, the TIR-1/JNK-1 pathway accelerates forgetting of olfactory adaptation by facilitating neural secretion from AWC sensory neurons. In this study, to identify the downstream effectors of the TIR-1/JNK-1 pathway, we conducted a genetic screen for suppressors of the gain-of-function mutant of tir-1 (ok1052), which shows excessive forgetting. Our screening showed that three proteins—a membrane protein, MACO-1; a receptor tyrosine kinase, SCD-2; and its putative ligand, HEN-1—regulated forgetting downstream of the TIR-1/JNK-1 pathway. We further demonstrated that MACO-1 and SCD-2/HEN-1 functioned in parallel genetic pathways, and only MACO-1 regulated forgetting of olfactory adaptation to isoamyl alcohol, which is an attractive odorant sensed by different types of sensory neurons. In olfactory adaptation, odor-evoked Ca2+ responses in olfactory neurons are attenuated by conditioning and recovered thereafter. A Ca2+ imaging study revealed that this attenuation is sustained longer in maco-1 and scd-2 mutant animals than in wild-type animals like the TIR-1/JNK-1 pathway mutants. Furthermore, temporal silencing by histamine-gated chloride channels revealed that the neuronal activity of AWC neurons after conditioning is important for proper forgetting. We propose that distinct signaling pathways, each of which has a specific function, may coordinately and temporally regulate forgetting by controlling sensory responses.

    DOI： 10.1523/JNEUROSCI.0031-17.2017

  • Forgetting in C. elegans is accelerageted by neuronal communication via the TIR-1/JNK-1 pathway Reviewed International journal

    Akitoshi Inoue, Etsuko Sawatari, Naoki Hisamoto, Tomohiro Kitazono, Takayuki Teramoto, Manabi Fujiwara, Kunihiro Matsumoto, Takeshi Ishihara

    Cell Reports   3 ( 3 )   809 - 819   2013.3

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    線虫の嗅覚順応をモデルとして、忘却機構の解析を行ったところ、忘却を促進するシグナルが外部環境に応じて放出されていることが明らかになった。これは能動的な忘却制御システムがあることを示している。

    DOI： 10.1016/j.celrep.

  • Odour concentration -dependent olfactory preference change in C. elegans. Reviewed International journal

    Yoshida K, Hirotsu T, Tagawa T, Oda S, Wakabayashi T, Iino Y, Ishihara T.

    Nature Communications   3   2012.3

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    動物は、同じ刺激であっても強さに応答を変える場合がある。線虫においては、低濃度では誘引される物質に対して高濃度では忌避するという現象がある。このメカニズムを解析したところ、主に方向転換を使って忌避していること、低濃度の場合と高濃度の場合で感覚するニューロンが異なっていることなどが明らかになった。

  • An expanded palette of genetically encoded Ca2+ indicators Reviewed International coauthorship International journal

    Zhao Y, Araki S, Wu J, Teramoto T, Chang YF, Nakano M, Abdelfattah AS, Fujiwara M, Ishihara T, Nagai T, Campbell RE

    Science   333   2011.9

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    細胞内のCa2+の変化を、蛍光タンパク質Ca2+センサーを用いて調べることができる。この論文では、蛍光タンパク質Ca2+センサーに変異を導入し、これまでの数倍感度が高いセンサーを開発した。さらに、これまでなかった、赤色蛍光タンパク質Ca2+センサーを開発した。これらのセンサーは、培養細胞だけでなく個体で特定の神経細胞での活動測定にも有用であることを明らかにした。

  • Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans. Reviewed International coauthorship International journal

    Shinkai Y, Yamamoto Y, Fujiwara M, Tabata T, Murayama T, Hirotsu T, Ikeda DD, Tsunozaki M, Iino Y, Bargmann CI, Katsura I, Ishihara T.

    Journal of Neuroscience   31 ( 8 )   2011.2

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    動物は、同時に受容している多くの感覚情報のなかから、生存に適した情報を選択して、それに応答して行動している。しかし、その制御を行っている神経・分子メカニズムは、明らかになっていない。本研究では、線虫C. elegansをモデルとして、２つの相反する刺激に対する応答を解析した。その結果、一対に介在ニューロンにおいて、グアニル酸シクラーゼと受容体チロシンキナーゼを介して、情報処理が行われていることを明らかにした。

  • 2.A novel zf-MYND protein, CHB-3, mediates guanylyl cyclase localization to sensory cilia and controls body size of Caenorhabditis elegans. Reviewed International coauthorship International journal

    Fujiwara M, Teramoto T, Ishihara T, Ohshima Y, McIntire SL.

    Plos Genetics   6 ( 11 )   2010.11

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  • A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans. Reviewed International journal

    Hayashi Y., Hirotsu T., Iwata R., Kage-Nakadai E., Kunitomo H., Ishihara T., Iino Y. and Kubo T.

    Nature Neuroscience   12   2009.6

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  • ADBP-1 regulates an ADAR RNA-editing enzyme to antagonize RNAi-mediated gene silencing in C.elegans. Reviewed International journal

    Ohta, H., Fujiwara, M., Ohshima, Y. and Ishihara, T.

    Genetics   2008.7

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  • Caenorhabditis elegans integrates the signals of butanone and food to enhance chemotaxis to butanone. Reviewed International journal

    Torayama I, Ishihara T, Katsura I

    Journal of Neuroscience   2007.1

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  • Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide Reviewed

    Ishihara,T., Shigemoto,R., Mori,K., Takahashi,K., and Nagata,S

    Neuron   8   811   1992

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/0896-6273(92)90101-i

  • Molecular cloning and expression of a cDNA encoding the secretin receptor Reviewed

    Ishihara,T., Nakamura,S., Kaziro,Y., Takahashi,T., Takahashi, K., and Nagata,S

    EMBO Journal   10   1635   1991

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1002/j.1460-2075.1991.tb07686.x

  • Mechanism of sensory perception unveiled by simultaneous measurement of membrane voltage and intracellular calcium Reviewed

    Terumasa Tokunaga, Noriko Sato, Mary Arai, Takumi Nakamura, Takeshi Ishihara

    Communications Biology   7 ( 1 )   1150   2024.9   （ eISSN:2399-3642 ）

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Communications Biology  

    Measuring neuronal activity is important for understanding neuronal function. Ca<sup>2+</sup> imaging by genetically encoded calcium indicators (GECIs) is a powerful way to measure neuronal activity. Although it revealed important aspects of neuronal function, measuring the neuronal membrane voltage is important to understand neuronal function as it triggers neuronal activation. Recent progress of genetically encoded voltage indicators (GEVIs) enabled us fast and precise measurements of neuronal membrane voltage. To clarify the relation of the membrane voltage and intracellular Ca<sup>2+</sup>, we analyzed neuronal activities of olfactory neuron AWA in Caenorhabditis elegans by GCaMP6f (GECI) and paQuasAr3 (GEVI) responding to odorants. We found that the membrane voltage encodes the stimuli change by the timing and the duration by the weak semi-stable depolarization. However, the change of the intracellular Ca<sup>2+</sup> encodes the strength of the stimuli. Furthermore, ODR-3, a G-protein alpha subunit, was shown to be important for stabilizing the membrane voltage. These results suggest that the combination of calcium and voltage imaging provides a deeper understanding of the information in neural circuits. (Figure presented.)

    DOI： 10.1038/s42003-024-06778-2

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  • Ensemble dynamics and information flow deduction from whole-brain imaging data. Reviewed

    Toyoshima Y, Sato H, Nagata D, Kanamori M, Jang MS, Kuze K, Oe S, Teramoto T, Iwasaki Y, Yoshida R, Ishihara T, Iino Y.

    Plos Computational Biology   20 ( 3 )   e1011848   2024.3   （ ISSN:1553-734X eISSN:1553-7358 ）

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：PLoS Computational Biology  

    The recent advancements in large-scale activity imaging of neuronal ensembles offer valuable opportunities to comprehend the process involved in generating brain activity patterns and understanding how information is transmitted between neurons or neuronal ensembles. However, existing methodologies for extracting the underlying properties that generate overall dynamics are still limited. In this study, we applied previously unexplored methodologies to analyze time-lapse 3D imaging (4D imaging) data of head neurons of the nematode Caenorhabditis elegans. By combining time-delay embedding with the independent component analysis, we successfully decomposed whole-brain activities into a small number of component dynamics. Through the integration of results from multiple samples, we extracted common dynamics from neuronal activities that exhibit apparent divergence across different animals. Notably, while several components show common cooperativity across samples, some component pairs exhibited distinct relationships between individual samples. We further developed time series prediction models of synaptic communications. By combining dimension reduction using the general framework, gradient kernel dimension reduction, and probabilistic modeling, the overall relationships of neural activities were incorporated. By this approach, the stochastic but coordinated dynamics were reproduced in the simulated whole-brain neural network. We found that noise in the nervous system is crucial for generating realistic whole-brain dynamics. Furthermore, by evaluating synaptic interaction properties in the models, strong interactions within the core neural circuit, variable sensory transmission and importance of gap junctions were inferred. Virtual optogenetics can be also performed using the model. These analyses provide a solid foundation for understanding information flow in real neural networks.

    DOI： 10.1371/journal.pcbi.1011848

    DOI： 10.1371/journal.pcbi.1011848

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    Open data URL： https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011848

  • WormTensor: a clustering method for time-series whole-brain activity data from C. elegans Reviewed International journal

    Koki Tsuyuzaki , Kentaro Yamamoto, Yu Toyoshima , Hirofumi Sato3, Manami Kanamori , Takayuki Teramoto , Takeshi Ishihara , Yuichi Iino , Itoshi Nikaido

    BMC Bioinformatics   24 ( 1 )   254   2023.6   （ ISSN:1471-2105 eISSN:1471-2105 ）

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Background

    In the field of neuroscience, neural modules and circuits that control biological functions have been found throughout entire neural networks. Correlations in neural activity can be used to identify such neural modules. Recent technological advances enable us to measure whole-brain neural activity with single-cell resolution in several species including $$Caenorhabditis\ elegans$$. Because current neural activity data in C. elegans contain many missing data points, it is necessary to merge results from as many animals as possible to obtain more reliable functional modules.

    Results

    In this work, we developed a new time-series clustering method, , to identify functional modules using whole-brain activity data from C. elegans. uses a distance measure, modified shape-based distance to account for the lags and the mutual inhibition of cell–cell interactions and applies the tensor decomposition algorithm multi-view clustering based on matrix integration using the higher orthogonal iteration of tensors (HOOI) algorithm (), which can estimate both the weight to account for the reliability of data from each animal and the clusters that are common across animals.

    Conclusion

    We applied the method to 24 individual C. elegans and successfully found some known functional modules. Compared with a widely used consensus clustering method to aggregate multiple clustering results, showed higher silhouette coefficients. Our simulation also showed that is robust to contamination from noisy data. is freely available as an /CRAN package https://cran.r-project.org/web/packages/WormTensor.

    DOI： 10.1186/s12859-023-05230-2

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    Other Link： https://link.springer.com/article/10.1186/s12859-023-05230-2/fulltext.html

  • Cell Tracking in C. elegans with Cell Position Heatmap-Based Alignment and Pairwise Detection

    Shiku, K; Shirai, H; Ishihara, T; Bise, R

    2023 45TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY, EMBC   2023   （ ISSN:1557-170X ISBN:979-8-3503-2447-1 eISSN:1558-4615 ）

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    Publisher：Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS  

    3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning. Second, cell detection is often inconsistent in consecutive frames due to touching cells and low-contrast images, and these inconsistent detections affect the tracking performance worse. In this paper, we propose a cell tracking method to address these issues, which has two main contributions. First, we introduce cell position heatmap-based non-rigid alignment with test-time fine-tuning, which can warp the detected points to near the positions at the next frame. Second, we propose a pairwise detection method, which uses the information of detection results at the previous frame for detecting cells at the current frame. The experimental results demonstrate the effectiveness of each module, and the proposed method achieved the best performance in comparison.

    DOI： 10.1109/EMBC40787.2023.10340619

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  • Deducing ensemble dynamics and information flow from the whole-brain imaging data Reviewed

    Yu Toyoshima, Hirofumi Sato, Daiki Nagata, Manami Kanamori, Moon Sun Jang, Koyo Kuze, Suzu Oe, Takayuki Teramoto, Yuishi Iwasaki, Ryo Yoshida, Takeshi Ishihara, Yuichi Iino

    2022.11

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    Publisher：Cold Spring Harbor Laboratory  

    Abstract

    Recent development of large-scale activity imaging of neuronal ensembles provides opportunities for understanding how activity patterns are generated in the brain and how information is transmitted between neurons or neuronal ensembles. However, methodologies for extracting the component properties that generate overall dynamics are still limited. In this study, the results of time-lapse 3D imaging (4D imaging) of head neurons of the nematodeC. eleganswere analyzed by hitherto unemployed methodologies.

    By combining time-delay embedding with independent component analysis, the whole-brain activities were decomposed to a small number of component dynamics. Results from multiple samples, where different subsets of neurons were observed, were further combined by matrix factorization, revealing common dynamics from neuronal activities that are apparently divergent across sampled animals. By this analysis, we could identify components that show common relationships across different samples and those that show relationships distinct between individual samples.

    We also constructed a network model building on time-lagged prediction models of synaptic communications. This was achieved by dimension reduction of 4D imaging data using the general framework gKDR (gradient kernel dimension reduction). The model is able to decompose basal dynamics of the network. We further extended the model by incorporating probabilistic distribution, resulting in models that we call gKDR-GMM and gKDR-GP. The models capture the overall relationships of neural activities and reproduce the stochastic but coordinated dynamics in the neural network simulation. By virtual manipulation of individual neurons and synaptic contacts in this model, information flow could be estimated from whole-brain imaging results.

    DOI： 10.1101/2022.11.18.517011

  • EGL-4/PKG regulates the role of an interneuron in a chemotaxis circuit of C. elegans through mediating integration of sensory signals Invited Reviewed International journal

    #Hino T, #Hirai S, @Ishihara T, @Fujiwara M.

    GENES TO CELLS   26 ( 6 )   411 - 425   2021.6

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    DOI： 10.1111/gtc.12849

  • 3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images Invited Reviewed International coauthorship International journal

    Wen C, Miura T, Voleti V, Yamaguchi K, Tsutsumi M, Yamamoto K, Otomo K, Fujie Y, @Teramoto T, @Ishihara T, Aoki K, Nemoto T, Hillman EM, Kimura KD.

    ELIFE   10   2021.3

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    DOI： 10.7554/eLife.59187

  • Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging Invited Reviewed International journal

    Harada, Kazuki; Chihara, Takami; Hayasaka, Yuki; Mita, Marie; Takizawa, Mai; Ishida, Kentaro; @Arai, Mary; Tsuno, Saki; Matsumoto, Mitsuharu; @Ishihara, Takeshi; Ueda, Hiroshi; Kitaguchi, Tetsuya; Tsuboi, Takashi

    SCIENTIFIC REPORTS   10 ( 1 )   2020.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/s41598-020-76440-4

  • Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans Reviewed

    Yu Toyoshima, Stephen Wu, Manami Kanamori, Hirofumi Sato, Moon Sun Jang, #Suzu Oe, #Yuko Murakami, @Takayuki Teramoto, Chanhyun Park, Yuishi Iwasaki, @Takeshi Ishihara, Ryo Yoshida, Yuichi Iino

    BMC biology   18 ( 1 )   2020.3

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    Background: Annotation of cell identity is an essential process in neuroscience that allows comparison of cells, including that of neural activities across different animals. In Caenorhabditis elegans, although unique identities have been assigned to all neurons, the number of annotatable neurons in an intact animal has been limited due to the lack of quantitative information on the location and identity of neurons. Results: Here, we present a dataset that facilitates the annotation of neuronal identities, and demonstrate its application in a comprehensive analysis of whole-brain imaging. We systematically identified neurons in the head region of 311 adult worms using 35 cell-specific promoters and created a dataset of the expression patterns and the positions of the neurons. We found large positional variations that illustrated the difficulty of the annotation task. We investigated multiple combinations of cell-specific promoters driving distinct fluorescence and generated optimal strains for the annotation of most head neurons in an animal. We also developed an automatic annotation method with human interaction functionality that facilitates annotations needed for whole-brain imaging. Conclusion: Our neuron ID dataset and optimal fluorescent strains enable the annotation of most neurons in the head region of adult C. elegans, both in full-automated fashion and a semi-automated version that includes human interaction functionalities. Our method can potentially be applied to model species used in research other than C. elegans, where the number of available cell-type-specific promoters and their variety will be an important consideration.

    DOI： 10.1186/s12915-020-0745-2

  • Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway Reviewed

    Yoshishige Kimura, Koji Tsutsumi, Alu Konno, Koji Ikegami, Saira Hameed, Tomomi Kaneko, Oktay Ismail Kaplan, @Takayuki Teramoto, @Manabi Fujiwara, @Takeshi Ishihara, Oliver E. Blacque, Mitsutoshi Setou

    Scientific reports   8 ( 1 )   2018.12

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    Glutamylation is a post-translational modification found on tubulin that can alter the interaction between microtubules (MTs) and associated proteins. The molecular mechanisms regulating tubulin glutamylation in response to the environment are not well understood. Here, we show that in the sensory cilia of Caenorhabditis elegans, tubulin glutamylation is upregulated in response to various signals such as temperature, osmolality, and dietary conditions. Similarly, tubulin glutamylation is modified in mammalian photoreceptor cells following light adaptation. A tubulin glutamate ligase gene ttll-4, which is essential for tubulin glutamylation of axonemal MTs in sensory cilia, is activated by p38 MAPK. Amino acid substitution of TTLL-4 has revealed that a Thr residue (a putative MAPK-phosphorylation site) is required for enhancement of tubulin glutamylation. Intraflagellar transport (IFT), a bidirectional trafficking system specifically observed along axonemal MTs, is required for the formation, maintenance, and function of sensory cilia. Measurement of the velocity of IFT particles revealed that starvation accelerates IFT, which was also dependent on the Thr residue of TTLL-4. Similarly, starvation-induced attenuation of avoidance behaviour from high osmolality conditions was also dependent on ttll-4. Our data suggest that a novel evolutionarily conserved regulatory system exists for tubulin glutamylation in sensory cilia in response to the environment.

    DOI： 10.1038/s41598-018-26694-w

  • SPF-CellTracker: Tracking Multiple Cells with Strongly-Correlated Moves Using a Spatial Particle Filter Reviewed International journal

    Hirose, Osamu; Kawaguchi, Shotaro; Tokunaga, Terumasa; Toyoshima, Yu; @Teramoto, Takayuki; @Kuge, Sayuri; @Ishihara, Takeshi; Iino, Yuichi; Yoshida, Ryo

    IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS   15 ( 6 )   1822 - 1831   2018.11

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    DOI： 10.1109/TCBB.2017.2782255

  • Molecular and Neuronal Mechanisms of Forgetting Invited

    @Mary Arai, @Takeshi Ishihara

    Brain and Nerve   70   689 - 697   2018.7

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

    DOI： 10.11477/mf.1416201070

  • An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease Reviewed

    @Sayuri Hara-Kuge, #Tomonobu Nishihara, Tomoki Matsuda, #Tomohiro Kitazono, @Takayuki Teramoto, Takeharu Nagai, @Takeshi Ishihara

    PLoS One   13 ( 4 )   2018.4

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    Sensory processing is regulated by the coordinated excitation and inhibition of neurons in neuronal circuits. The analysis of neuronal activities has greatly benefited from the recent development of genetically encoded Ca2+ indicators (GECIs). These molecules change their fluorescence intensities or colours in response to changing levels of Ca2+ and can, therefore, be used to sensitively monitor intracellular Ca2+ concentration, which enables the detection of neuronal excitation, including action potentials. These GECIs were developed to monitor increases in Ca2+ concentration; therefore, neuronal inhibition cannot be sensitively detected by these GECIs. To overcome this difficulty, we hypothesised that an inverse-type of GECI, whose fluorescence intensity increases as Ca2+ levels decrease, could sensitively monitor reducing intracellular Ca2+ concentrations. We, therefore, developed a Ca2+ indicator named inverse-pericam 2.0 (IP2.0) whose fluorescent intensity decreases 25-fold upon Ca2+ binding in vitro. Using IP2.0, we successfully detected putative neuronal inhibition by monitoring the decrease in intracellular Ca2+ concentration in AWCON and ASEL neurons in Caenorhabditis elegans. Therefore, IP2.0 is a useful tool for studying neuronal inhibition and for the detailed analysis of neuronal activities in vivo.

    DOI： 10.1371/journal.pone.0194707

  • Accurate Automatic Detection of Densely Distributed Cell Nuclei in 3D Space Reviewed

    Yu Toyoshima, Terumasa Tokunaga, Osamu Hirose, Manami Kanamori, Takayuki Teramoto, Moon Sun Jang, Sayuri Kuge, Takeshi Ishihara, Ryo Yoshida, Yuichi Iino

    PLoS Computational Biology   12 ( 6 )   2016.6

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    To measure the activity of neurons using whole-brain activity imaging, precise detection of each neuron or its nucleus is required. In the head region of the nematode C. elegans, the neuronal cell bodies are distributed densely in three-dimensional (3D) space. However, no existing computational methods of image analysis can separate them with sufficient accuracy. Here we propose a highly accurate segmentation method based on the curvatures of the iso-intensity surfaces. To obtain accurate positions of nuclei, we also developed a new procedure for least squares fitting with a Gaussian mixture model. Combining these methods enables accurate detection of densely distributed cell nuclei in a 3D space. The proposed method was implemented as a graphical user interface program that allows visualization and correction of the results of automatic detection. Additionally, the proposed method was applied to time-lapse 3D calcium imaging data, and most of the nuclei in the images were successfully tracked and measured.

    DOI： 10.1371/journal.pcbi.1004970

  • Gonadal Maturation Changes Chemotaxis Behavior and Neural Processing in the Olfactory Circuit of Caenorhabditis elegans Reviewed

    Manabi Fujiwara, Itaru Aoyama, Takahiro Hino, Takayuki Teramoto, Takeshi Ishihara

    Current Biology   26 ( 12 )   1522 - 1531   2016.1

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    Many animal species change their behavior according to their stage of development. However, the mechanisms involved in translating their developmental stage into the modifications of the neuronal circuits that underlie these behavioral changes remain unknown. Here we show that Caenorhabditis elegans changes its olfactory preferences during development. Larvae exhibit a weak chemotactic response to the food-associated odor diacetyl, whereas adults exhibit a strong response. We show that germline loss, caused either by laser ablation of germline precursor cells or mutations, results in a diacetyl-specific chemotactic defect in adult animals. These results suggest that germline cells, which proliferate dramatically during the larval stages, enhance chemotaxis to diacetyl. Removal experiments of specific neurons suggested that AWA olfactory neurons and their downstream interneurons, AIA and AIB, are required for germline-dependent chemotactic enhancement. Calcium imaging in animals lacking germline cells indicates that the neural responses of AWA and AIB to diacetyl stimuli are decreased compared with animals with an intact germline. These changes in neural activities may at least partly explain the behavioral change of animals lacking germline cells. Furthermore, this germline-dependent chemotactic change depends on the transcription factor DAF-16/FOXO. We find that organismal behavior changes throughout development by integrating information about physiological status from internal tissues to modify a simple sensory circuit.

    DOI： 10.1016/j.cub.2016.04.058

  • The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans Reviewed International journal

    Manabi Fujiwara, Takahiro Hino, Ryuta Miyamoto, Hitoshi Inada, Ikue Mori, Makoto Koga, Koji Miyahara, Yasumi Ohshima, Takeshi Ishihara

    GENETICS   201 ( 4 )   1497 - +   2015.12

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    DOI： 10.1534/genetics.115.177543

  • Metabotropic glutamate receptors Modulators of context-dependent feeding behaviour in C. elegans Reviewed International coauthorship

    James Dillon, Christopher J. Franks, Caitriona Murray, Richard J. Edwards, Fernando Calahorro, Takeshi Ishihara, Isao Katsura, Lindy Holden-Dye, Vincent O'Connor

    Journal of Biological Chemistry   290 ( 24 )   15052 - 15065   2015.6

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    Glutamatergic neurotransmission is evolutionarily conserved across animal phyla. A major class of glutamate receptors consists of the metabotropic glutamate receptors (mGluRs). In C. elegans, three mGluR genes, mgl-1, mgl-2, and mgl-3, are organized into three subgroups, similar to their mammalian counterparts. Cellular reporters identified expression of the mgls in the nervous system of C. elegans and overlapping expression in the pharyngeal microcircuit that controls pharyngeal muscle activity and feeding behavior. The overlapping expression of mgls within this circuit allowed the investigation of receptor signaling per se and in the context of receptor interactions within a neural network that regulates feeding.Weutilized the pharmacological manipulation of neuronally regulated pumping of the pharyngeal muscle in the wild-type and mutants to investigate MGL function. This defined a net mgl-1-dependent inhibition of pharyngeal pumping that is modulated by mgl-3 excitation. Optogenetic activation of the pharyngeal glutamatergic inputs combined with electrophysiological recordings from the isolated pharyngeal preparations provided further evidence for a presynaptic mgl-1-dependent regulation of pharyngeal activity. Analysis of mgl-1, mgl-2, and mgl-3 mutant feeding behavior in the intact organism after acute food removal identified a significant role for mgl-1 in the regulation of an adaptive feeding response. Our data describe the molecular and cellular organization of mgl-1, mgl-2, and mgl-3. Pharmacological analysis identified that, in these paradigms, mgl-1 and mgl-3, but not mgl-2, can modulate the pharyngeal microcircuit. Behavioral analysis identified mgl-1 as a significant determinant of the glutamate-dependent modulation of feeding, further highlighting the significance of mGluRs in complex C. elegans behavior.

    DOI： 10.1074/jbc.M114.606608

  • Automated detection and tracking of many cells by using 4D live-cell imaging data

    Terumasa Tokunaga, Osamu Hirose, Shotaro Kawaguchi, Yu Toyoshima, Takayuki Teramoto, Hisaki Ikebata, Sayuri Kuge, Takeshi Ishihara, Yuichi Iino, Ryo Yoshida

    BIOINFORMATICS   30 ( 12 )   2014.6

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    DOI： 10.1093/bioinformatics/btu271

  • Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish Reviewed

    Toshio Shibata, Sanae Sekihara, Takumi Fujikawa, Ryuta Miyaji, Kouki Maki, Takeshi Ishihara, Takumi Koshiba, Shun-Ichiro Kawabata

    Science Signaling   6 ( 285 )   2013.7

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    Cross-linking of proteins by mammalian transglutaminases (TGs) plays important roles in physiological phenomena such as blood coagulation and skin formation. We show that Drosophila TG suppressed innate immune signaling in the gut. RNA interference (RNAi) directed against TG reduced the life span of flies reared under conventional nonsterile conditions but not of those raised under germ-free conditions. In conventionally reared flies, TG RNAi enhanced the expression of genes encoding antimicrobial peptides in the immune deficiency (IMD) pathway. Wild-type flies that ingested gut lysates prepared from conventionally reared TG RNAi-treated flies had shorter life spans. In conventionally reared flies, TG RNAi triggered apoptosis in the gut and induced the nuclear translocation of Relish, the NF-κB (nuclear factor κB)-like transcription factor of the IMD pathway. Wild-type flies that ingested synthetic amine donors, which inhibit the TG-catalyzed protein-protein cross-linking reaction, showed nuclear translocation of Relish and enhanced expression of genes encoding IMD-controlled antimicrobial peptide genes in the gut. We conclude that TG-catalyzed Relish cross-linking suppressed the IMD signaling pathway to enable immune tolerance against commensal microbes.

    DOI： 10.1126/scisignal.2003970

  • A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer Reviewed International journal

    Osamu Sasaki, Misa Kuboyama, Takeshi Ishihara, Emi Suzuki, Shun-ichiro Kawabata, TAKUMI KOSHIBA

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH   1833 ( 5 )   2013.2

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    DOI： 10.1016/j.bbamcr.2013.01.010

  • Temporally-regulated quick activation and inactivation of Ras is important for olfactory behaviour Reviewed International journal

    T. Uozumi, Takaaki Hirotsu, K. Yoshida, R. Yamada, A. Suzuki, G. Taniguchi, Y. Iino, Takeshi Ishihara

    SCIENTIFIC REPORTS   2   2012.7

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    DOI： 10.1038/srep00500

  • Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans. Reviewed International journal

    Yamada K, Hirotsu T, Matsuki M, Butcher RA, Tomioka M, Ishihara T, Clardy J, Kunitomo H, Iino Y.

    Science.   329 ( 5999 )   2010.9

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    動物は、集団密度などの環境によって、外界シグナルに対する応答を変化させる。線虫C. elegansをモデルとして、動物の集団密度が行動可塑性に与える影響を解析した。その結果、線虫は、集団密度の情報をフェロモンとして受容し、ペプチド性シグナルSNET-1と、そのシグナル強度を変化させるNEP-2を介して、嗅覚順応の制御を行っていることを明らかにした。

  • FLR-2, the glycoprotein hormone alpha subunit, is involved in the neural control of intestinal functions in Caenorhabditis elegans. Reviewed International journal

    Oishi A., Gengyo-Ando K., Mitani S., Mohri-Shiomi A., Kimura K.D., Ishihara T., Katsura I.

    Genes to Cells   14   2009.7

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  • Behavioural assay for olfactory plasticity in C. elegans. International journal

    Hirotsu T., Hayashi Y., Iwata R., Kunitomo H., Kage-Nakadai E., Kubo T., Ishihara T. and Iino Y.

    Nature Protocols   2009.7

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  • Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans. Reviewed International coauthorship International journal

    Bauer Huang,SL., Saheki, Y., Vanhoven, MK., Torayama, I., Ishihara, T., Katsura, I, van der Linden, A., Sengupta, P. and Bargmann, CI.

    Neural Development   2007.12

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  • A Genome-wide Survey and Systematic RNAi-based Characterization of Helicase-like Genes in Caenorhabditis elegans. Reviewed International journal

    Eki, T., Ishihara ,T., Katsura, I. & Hanaoka, F.

    DNA Research   2007.8

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  • IFT-81 and IFT74 are required for intraflagellar transport in C. elegans Reviewed International journal

    Kobayashi T, Gengyo-Ando K, Ishihara T, Katsura I, Mitani S

    Genes To Cells   2007.5

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  • Two mutations lead to a super small body size in the nematode C. elegans Reviewed International journal

    Watanabe N, Ishihara T, Ohshima Y

    Genes to Cells   2007.5

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  • Multidrug resistance-associated protein MRP-1 regulates dauer diapause by its export activity in Caenorhabditis elegans. Reviewed International journal

    Yabe T., Suzuki N., Furukawa T.,Ishihara T.,Katsura I.

    Development, 132,3197-3207   2005.1

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  • "FLR-4, a novel Serine/Threonine protein kinase, regulates defecation rhythm in Caenorhabditis elegans." Reviewed International journal

    Take-Uchi M, Kobayashi Y, Kimura KD, Ishihara T, Katsura I.

    Mol Biol Cell, 16.1355-1365(2005)   2005.1

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  • TBX2/TBX3 transcriptional factor homolog controls olfactory adaptation in Caenorhabditis elegans Reviewed International journal

    Miyahara,K., Suzuki,N., Ishihara,T., Tsuchiya,E., Katsura,I.

    Journal of Neurobiology, 58, 392-402 (2004)   2004.1

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    Language：English   Publishing type：Research paper (scientific journal)  

  • SDF-9, a protein tyrosine pshophatse-like molecule, regulates the L3/dauer developmental decision through hormonal signaling in C.elegans. Reviewed International journal

    Ohkura,K, Suzuki,N., Ishihara,T., Katsura,I.

    Development   2003.1

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  • HEN-1, a secretory protein with an LDL receptor motif, regulates sensory integration and learning in Caenorhabditis elegans Reviewed International journal

    Ishihara,T. Iino,Y. Mohri,A., Mori,I., Gengyo-Ando,K., Mitani,S., Katsura,I

    Cell   2002.1

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  • Mutations affecting nerve attachment of Caenorhabditis elegans Reviewed International journal

    Shioi,G., Shoji,M., Nakamura,M., Ishihara,T., Katsura,I., Fujisawa,H., and Takagi,S

    Genetics   2001.1

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  • The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moultingand reproduction in Caenorhabditis elegans Reviewed International coauthorship International journal

    Asahina,M., Ishihara,T., Jindra,M., Kohara,Y., Katsura,I. and Hirose,S

    Genes to Cells   2000.1

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  • Identification and characterization of the high-affinity cholinetransporter Reviewed International journal

    Okuda,T., Haga,T., Kanai,Y., Endou,H., Ishihara,T., and Katsura,I

    Nature Neuroscience   2000.1

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  • Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Reviewed International journal

    Aoki,H., Sato,S., Takanami,T., Ishihara,T., Katsura,I., Takahashi,H., and Higashitani,A.

    Molecular and General Genetics   2000.1

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  • Genomic Organization and Chromosomal Location of the Mouse Vasoactive Intestinal Polypeptide 1 (VPAC1) Receptor Reviewed International journal

    Hashimoto,H. Nishino,A. Shintani,N., Hagihara,N. and Copeland,N.G., Jenkins,N.A., Yamamoto,K., Matsuda,T., Ishihara,T., Nagata,S., and Baba,A.

    Genomics   1999.1

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  • UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans. Reviewed International coauthorship International journal

    Winnier,A.R., Meir,J.Y.-J., Ross,J.M., Tavernarakis,N., Driscoll,M.,Ishihara,T., Katsura,I., and Miller III,D.M.

    Genes and Development   1999.1

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  • A novel WD40 protein, CHE-2, acts cell-autonomously in the formation of C. elegans sensory cilia. Reviewed International journal

    Fujiwara,M., Ishihara,T., and Katsura,I

    Development   1999.1

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  • An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans. Reviewed International journal

    Take-uchi,M. Kawakami,M., Ishihara,T., Amano, K.Kondo, and I.Katsura

    Proc.Natl.Acad.Sci.USA   1998.1

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  • Characterization of a Caenorhabditis elegans recA-like Gene Ce-rdh-1 Involved in Meiotic Recombination Reviewed International journal

    Takanami,T., Sato, S., Ishihara,T., Katsura,I. Takahashi,H. and Higashitani,A.

    DNA Research   1998.1

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  • Characterization of a Caenorhabditis elegans recA-like Gene Ce-rdh-1 Involved in Meiotic Recombination Reviewed

    Takanami,T., Sato, S., Ishihara,T., Katsura,I. Takahashi,H. and Higashitani,A.

    DNA Research   5   373   1998

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  • An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans Reviewed

    Take-uchi,M. Kawakami,M., Ishihara,T., Amano, K.Kondo, and I.Katsura

    Proc.Natl.Acad.Sci.USA   95   11775   1998

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1073/pnas.95.20.11775

  • hch-1, a gene required for normal hatching and normal migration of a neuroblast in C. elegans, encodes a protein related to TOLLOID and BMP-1 Reviewed

    Hishida,R., Ishihara,T., Kondo,K., and Katsura,I.

    EMBO Journal   15   4111   1996

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1002/j.1460-2075.1996.tb00786.x

  • Isolation, characterization, and epistasis of fluoride-resistant mutants of Caenorhabditis elegans. Reviewed

    Katsura,I., Kondo,K., Amano,T., Ishihara,T., and Kawakami,M.

    Genetics   136   145   1994

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1093/genetics/136.1.145

  • Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide Reviewed

    Hashimoto,H., Ishihara,T., Shigemoto,R., Mori,K., and Nagata,S.

    Neuron   11   333   1993

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/0896-6273(93)90188-w

  • Assignment of human pepshinogen C (PGC) gene to chromosome 6. Reviewed

    Takahara,K., Fukushige,S., Murotsu,T., Ichihara,Y., Hayano,T., Ishihara,T.,Takahashi,K., and Matsubara,K.

    Cytogenetics and Cell Genetics,   52   100   1989

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1159/000132853

  • Primary structure and transcriptional regulation of rat pepsinogenC gene. Reviewed

    Ishihara,T., Ichihara,Y., Hayano,T., Katsura,I., Sogawa,K., Fujii-kuriyama,Y., andTakahashi,K.

    Journal of Biological Chemistry   264   10193   1989

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/S0021-9258(18)81784-7

  • DNA methylation and expression of the rat pepsinogen gene in embryonic, adult and neoplastictissues. Reviewed

    Ichinose,M., Miki,K., Furihata,C., Tatematsu,M. Ichihara,Y., Ishihara,T., Katsura,I.,Sogawa,K., Fujii-Kuriyama,Y., Tanji,M., Oka,H., Matsushima,T. and Takahashi,K.

    Cancer Research   48   1603   1988

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  • Cell-specific hypomethylation of the pepsinogen gene in pepsinogen-producing cells.

    Ichinose,M., Miki,K., Tatematsu,M., Furihata,C., Ichihara,Y., Ishihara,T., Tanji,M., Oka,H.,Hinohara,Y., Takahashi,T., Kageyama,T., and Takahashi,K.

    Biochemical and Biophysical Research Communications,   155   670   1988

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/s0006-291x(88)80547-3

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Presentations

  • 神経ペプチドNLP-47とその受容体GNRR-1は、線虫C. elegansの嗅覚学習の忘却を促進する

    #Yuuki Onishi #Jamine Teo, @Takeshi Ishihara

    日本神経科学学会大会（Neuro2024)  2024.7 

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    Event date： 2024.7

    Language：English   Presentation type：Oral presentation (general)  

    Venue：沖縄   Country：Japan  

  • Forgetting of olfactory memory is specifically accelerated through GnRH-related signals by erasing its memory trace in Caenorhabditis elegans International conference

    #Onishi,Y. @Arai.M, #Hooi-Min Teo,J., #Kitazono T, @Ishihara T.

    Neuronal Circuit  2024.3 

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    Event date： 2024.4

    Language：English  

    Venue：Cold Spring Harbor   Country：United States  

  • Identification of Neuropeptides Accelerating Forgetting in C. elegans with A Reverse Genetic Approach International conference

    #Onishi, Y. #Teo, J., #Kitazono, T., ＠Ishihara, T

    23rd International C.elegans Conference  2021.6 

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    Event date： 2024.4

    Language：English  

    Venue：オンライン   Country：Other  

  • Diacylglycerol content controls proper memory utilization through switching between forgetting and retrieving International conference

    @Arai, M., @Ishihara, T.

    International worm meeting 2021  2021.6 

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    Event date： 2024.4

    Language：English   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Other  

  • The regulation of olfactory circuit by EGL-4/PKG International conference

    ＃Hino, T., ＃Hirai, S., ＠Ishihara, T. Fujiwara, M.

    International worm meeting 2021  2021.6 

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    Event date： 2024.4

    Language：English   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Other  

  • 線⾍におけるAWC感覚神経由来の想起抑制シグナルの探索

    #荒⾦ 星之介 ＠ 新井 美存 ＃⼤⻄ 湧⼰ @⽯原 健

    第45回日本分子生物学会  2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Venue：兵庫県   Country：Japan  

  • 線⾍C. elegansの記憶の忘却を制御するシナプス伝達機構

    #星加 智⼦ @新井 美存 @藤原 学 @⽯原 健

    第45回日本分子生物学会  2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Venue：兵庫県   Country：Japan  

  • 線⾍C. elegansの全脳イメージングを⽤いた⾏動可塑性を担う機能的な神経回路の研究

    #青木千春 @⽯原 健

    第45回日本分子生物学会  2023.11 

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    Event date： 2023.11

    Language：Japanese  

    Venue：兵庫県   Country：Japan  

  • GnRH-related signal is required for forgetting of olfactory memory in C. elegans

    #大西湧己　@石原　健

    線虫研究の未来を創る研究会  2023.8 

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    Event date： 2023.8

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：兵庫県   Country：Japan  

  • 老化した線虫C. elegansにおける忘却の表現型

    #中園藍子　#大西湧己　@石原　健

    線虫研究の未来を創る研究会  2023.8 

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    Event date： 2023.8

    Language：Japanese  

    Venue：兵庫県   Country：Japan  

  • Neuropeptide NLP-47 and its receptor GNRR-1 are important for forgetting of olfactory memory in C. elegans International conference

    #Yuuki Onishi, @Mary Arai, #Jamine Hooi Min Teo, #Tomohiro Kitazono, @Takeshi Ishihara

    24th International C.elegans Meeting  2023.6 

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    Event date： 2023.6

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Glasgow   Country：United Kingdom  

  • 線虫の匂い識別行動を指標にした、嗅覚回路における匂い情報伝達経路の解析

    ＃徳升太一　＠⽯原健 ＠藤原学

    第44回日本分子生物学会年会  2022.12 

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    Event date： 2022.12

    Language：Japanese  

    Country：Japan  

  • 線⾍ C. elegans の介在神経における複数の嗅覚情報の統合機構

    ＃東亮太郎 ＠⽯原健 ＠藤原学

    第44回日本分子生物学会年会  2022.12 

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    Event date： 2022.12

    Language：Japanese  

    Country：Japan  

  • Regulation of diacylglycerol content in olfactory neurons determines forgetting or retrieval of olfactory memory in Caenorhabditis elegans Invited International conference

    @Mary Arai, @Takeshi Ishihara

    記憶研究会  2022.10 

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    Event date： 2022.10

    Language：English   Presentation type：Oral presentation (general)  

    Venue：愛知県   Country：Japan  

  • Analyses of neuropeptides and receptors required for forgetting International conference

    #Yuuki Onishi @Takeshi Ishihara

    記憶研究会  2022.10 

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    Event date： 2022.10

    Language：English  

    Venue：愛知県   Country：Japan  

  • Neuropeptide NLP-47 and its receptor GNRR-1 promote forgetting of olfactory memory in C. elegans International conference

    #Onishi, Y. #Teo, J., ＠Ishihara, T

    23rd International C.elegans Conference  2022.6 

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    Event date： 2022.6

    Language：English   Presentation type：Oral presentation (general)  

    Venue：ウィーン   Country：Austria  

  • 線虫の嗅覚記憶の忘却におけるAIA介在神経の関与

    ＃Teo, J. ＠Ishihara, T

    第44回日本分子生物学会年会  2021.12 

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    Event date： 2021.12

    Language：Japanese  

    Country：Japan  

  • 神経ペプチドNLP-47は線虫のC. elegansの嗅覚学習の忘却を促進する

    ＃大西湧己、＃Teo, J.,＠石原　健

    第44回日本分子生物学会年会  2021.12 

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    Event date： 2021.12

    Language：Japanese  

    Country：Japan  

  • 線虫の脳における複数の情報処理の実行機構

    ＠藤原学　＃平井祥太　＠石原健

    第44回日本分子生物学会年会  2021.12 

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    Event date： 2021.12

    Language：Japanese  

    Country：Japan  

  • 線虫 C. elegans を用いて高精度な神経回路解析を行うことを目指し た実験系の改良

    #白井洸充　#大江紗　#村上悠子　豊島有　飯野雄一　他　@石原健

    第44回日本分子生物学会年会  2021.12 

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    Event date： 2021.12

    Language：Japanese  

    Country：Japan  

  • 線虫C. elegansにおいて、忘却促進シグナルを担う因子の逆遺伝学的解析

    ＃大西　湧己, ＃Jamine Hooi Min Teo, 北園　智弘 ＠石原　健

    第43回日本分子生物学会大会  2020.12 

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    Event date： 2020.12

    Language：Japanese  

    Venue：オンライン   Country：Japan  

  • 線虫C. elegansの膜電位応答動態を定量化するための画像処理パイプラインの開発

    徳永 旭将, 佐藤 則子, 岩崎 唯史 , 長村 徹 , 野見山 陸 , @石原 健

    第43回日本分子生物学会大会  2020.12 

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    Event date： 2020.12

    Language：Japanese  

    Venue：オンライン   Country：Japan  

  • 線虫の嗅覚神経においてポリモーダルな情報伝達を可能にする機構の解析

    日野　喬央、藤原　学、石原　健

    次世代脳プロジェクト　冬のシンポジウム  2018.12 

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    Event date： 2020.12 - 2018.12

    Language：Japanese  

    Venue：東京   Country：Japan  

  • 線虫C. elegans の性成熟にともなう匂いの好みの変化とその神経回路基盤

    藤原 学、和田 寛史、石原 健

    第41回日本分子生物学会年会  2018.11 

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    Event date： 2020.11 - 2018.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫C. elegansの嗅覚順応の忘却シグナルを担う神経ペプチドの解析

    大西 湧己、Jamine Hooi Min Teo、北園 智弘、石原 健

    第41回日本分子生物学会年会  2018.11 

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    Event date： 2020.11 - 2018.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫C.elegansのベンズアルデヒドに対する嗅覚順応の忘却変異体の解析

    木代成 優大、竹本 怜央、藤原 学、石原 健

    第41回日本分子生物学会年会  2018.11 

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    Event date： 2020.11 - 2018.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫の、成長に伴う行動変化における神経活動のカルシウムイメージング

    和田 寛史、藤原 学、石原　健

    第41回日本分子生物学会年会  2018.11 

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    Event date： 2020.11 - 2018.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 3DeeCellTracker: 三次元時系列画像データから細胞活動を追跡・抽出する深層学習を用いたソフトウェア

    木村 幸太郎1,2,3、三浦 拓也2、Venkatakaushik Voleti4、藤江 由香子2、@寺本 孝行5、@石原 健5、Elizabeth M.C. Hillman4、Chentao Wen1

    第43回日本神経科学大会  2020.7 

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    Event date： 2020.7

    Language：English   Presentation type：Oral presentation (general)  

    Venue：オンライン   Country：Japan  

  • 線虫の全脳イメージングとその解析

    石原健

    線虫研究の未来を創る会  2018.9 

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    Event date： 2020.1

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  • 線虫C.elegansの嗅覚順応の忘却シグナルを担う神経ペプチドの解析

    大西湧己　石原健

    線虫研究の未来を創る会  2018.9 

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    Event date： 2020.1

    Language：Japanese  

    Country：Japan  

  • 線虫C.elegansを用いたストレスによる感覚応答変化の原因解析

    串田琢哉　藤原学　石原健

    線虫研究の未来を創る会  2018.9 

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    Event date： 2020.1

    Language：Japanese  

    Country：Japan  

  • Cellular analysis if forgetting of an olfactory memory in Caenorhabditis elegans.

    Jamine Teo, Takeshi Ishihara

    線虫研究の未来を創る会  2018.9 

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    Event date： 2020.1

    Language：Japanese  

    Country：Japan  

  • How the gonadal maturation changes the neural processing in the olfactory circuitry of C.elegans.

    藤原学　石原健

    線虫研究の未来を創る会  2018.9 

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    Event date： 2020.1

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  • C. elegans における餌とフェロモンの情報統合回路の光遺伝学的解析

    藤原 学、山本 稜兼、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • The identification of genes responsible for forgetting of the olfactory adaptation to benzaldehyde in C.elegans

    Yuta Kiyonari, Reo Takemoto, Manabi Fujiwara, Takeshi Ishihara

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫の連合学習の記憶に基づく行動スイッチング:中枢神経回路活動可視化による解析

    大江 紗、村上 悠子、寺本 孝行、豊島 有、徳永 旭政、 Wu Stephan、広瀬 修、 Moon-Sun Jang、佐藤 博文、金森 真奈美、久下 小百合、岩崎 唯史、吉田 亮、飯野 雄一、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • Neuronal analyses in forgetting of an olfactory memory in Caenorhabditis elegans

    Jamine H. Teo, Tomohiro Kitazono, Takeshi Ishihara

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • Analyses of the regulation of active forgetting in the olfactory learning of C. elegans

    Mary Arai, Akitoshi Inoue, Takeshi Ishihara

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫において、お互いに補償する経路が飢餓時のジアセチル走性を維持している

    田中 想世花、徳田 雄太、新井 美存、藤原 学、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫C. elegansにおける忘却促進を担うシグナルの解析

    大西　湧己、Jamine Teo、北園　智弘、石原　健

    次世代脳プロジェクト2019年度冬のシンポジウム  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：東京   Country：Japan  

  • Whole neuronal analyses of the behavioral switching depending on associative learning in C. elegans

    大江 紗、村上 悠子、寺本 孝行、豊島 有、徳永 旭政、 Wu Stephan、広瀬 修、 Moon-Sun Jang、佐藤 博文、金森 真奈美、久下 小百合、岩崎 唯史、吉田 亮、飯野 雄一、石原 健

    次世代脳プロジェクト2019年度冬のシンポジウム  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：東京   Country：Japan  

  • Whole-brain calcium imaging analyses of dynamics of neural network in C. elegans

    Murakami Yuko, Suzu Oe, Motonari Ichinose, Takayuki Teramoto, Yu Toyoshima, Terumasa Tokunaga, Osamu Hirose, Wu Stephan, Jang Moon-Song, Hirofumi Sato, Sayuri Kuge, Yuishi Iwasaki, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    次世代脳プロジェクト2019年度冬のシンポジウム  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：東京   Country：Japan  

  • 嗅覚応答にかかわる機能的神経回路の可塑性はいかにして行動を制御するのか

    一ノ瀬 元成、村上 悠子、豊島 有、大江 紗、Stephen Wu、金森 真奈実、寺本 孝行、Moon-Sun Jang、佐藤 博文、吉田　亮、飯野 雄一、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫 C. elegansの腸細胞をモデルとした核内倍加メカニズムの解析

    徳田 雄太、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • Identification of Signaling Factors Accelerating Memory Erasing in C. elegans

    Yuuki Onishi, Jamine H. Teo, Tomohiro Kitazono, Takeshi Ishihara

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 全脳カルシウムイメージングによる線虫の神経動態解析

    村上 悠子、大江 紗、寺本 孝行、豊島 有、徳永 旭政、Stephan Wu、広瀬 修、Jang Moon-Sun、佐藤 博文、金森　真奈美、久下 小百合、 岩崎 唯史、吉田 亮、飯野 雄一、石原 健

    第42回日本分子生物学会年会  2019.12 

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    Event date： 2019.12

    Language：Japanese  

    Venue：福岡   Country：Japan  

  • Analyzing whole-brain dynamics of C. elegans with statistical approach International conference

    Murakami Yuko, Suzu Oe, Motonari Ichinose, Takayuki Teramoto, Yu Toyoshima, Terumasa Tokunaga, Osamu Hirose, Wu Stephan, Jang Moon-Song, Hirofumi Sato, Sayuri Kuge, Yuishi Iwasaki, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    The 20th International Conference on Systems Biology  2019.11 

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    Event date： 2019.11

    Language：Japanese  

    Venue：沖縄   Country：Japan  

  • Optogenetic analyses of information processing in the pheromone and food sensing network.

    Manabi Fujiwara, Ryoken Yamamoto, Takeshi Ishihara

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • The function of calmodulin kinase for the activity-dependent transcriptional regulation in ASI sensory neurons

    吉田　日向子、藤原　学、石原　健

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • Mechanisms of olfactory plasticity for butanone

    I. Kurokawa, N. Iwase, E. Sawatari, K. Kaieda, T. Ishihara

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • Is endoreduplication in intestine regulated by heterochronic genes?

    徳田　雄太、石原　健

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • Molecular and genetic analyses of the mechanism to promote chemotaxis to diacetyl during starvation (飢餓状態においてジアセチル走性を促進する機構の分子遺伝学的解析)

    田中　想世花、徳田　雄太、新井　美存、藤原　学、石原　健

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • Analyses of the regulation of forgetting by the food signals in the olfactory learning of C. elegans

    Mary Arai, Akitoshi Inoue, Takeshi Ishihara

    線虫研究の未来を創る会2019  2019.8 

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    Event date： 2019.8

    Language：Japanese  

    Venue：名古屋   Country：Japan  

  • 線虫の、特定の匂いに特異的な情報処理を可能にするPKG依存的な機構の解析

    日野 喬央、藤原 学、石原 健

    第42回日本神経科学大会  2019.7 

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    Event date： 2019.7 - 2019.6

    Language：Japanese  

    Venue：新潟   Country：Japan  

  • Gonadal maturation changes chemotaxis to a food-associated odorant through a guanylyl cyclase GCY-28. International conference

    M. Fujiwara, H. Wada, T. Ishihara

    22nd International C.elegans Conference  2019.6 

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    Event date： 2019.6

    Language：Japanese  

    Venue：ロサンゼルス   Country：United States  

  • Genetic Analyses of Neuropeptides Regulating Forgetting of Olfactory Adaptation in C. elegans. International conference

    Y. Onishi, J. Teo, T. Kitazono, T. Ishihara

    22nd International C.elegans Conference  2019.6 

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    Event date： 2019.6

    Language：Japanese  

    Venue：ロサンゼルス   Country：United States  

  • Cellular analysis in forgetting of an olfactory memory in Caenorhabditis elegans. International conference

    J.Hooi Min. Teo, Tomohiro Kitazono, Takeshi Ishihara

    22nd International C.elegans Conference  2019.6 

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    Event date： 2019.6

    Language：Japanese  

    Venue：ロサンゼルス   Country：United States  

  • Serotonin and DAG signals regulate active forgetting of olfactory adaptation. International conference

    M. Arai, A. Inoue, T. Ishihara

    22nd International C.elegans Conference  2019.6 

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    Event date： 2019.6

    Language：Japanese  

    Venue：ロサンゼルス   Country：United States  

  • 線虫の頭部全神経細胞の活動データに基づいた行動予測

    村上　悠子、大江　紗、勝目　拓海、寺本　孝行、豊島　有、徳永　旭将、広瀬　修、Wu Stephan、Jang Moon-Song、佐藤　博文、久下　小百合、岩崎　唯史、吉田　亮、飯野　雄一、石原　健

    第7回CREST生命動態領域会議  2019.1 

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    Event date： 2019.1

    Language：Japanese  

    Venue：東京   Country：Japan  

  • Analyzing whole neural activities to elusidate the mechanisms underlying sensory integration International conference

    Yuko Murakami, Suzu Oe, Takumi Katsume, Takayuki Teramoto, Yu Toyoshima, Terumasa Tokunaga, Osamu Hirose, Wu Stephan, Jang Moon-Song, Hirofumi Sato, Sayuri Kuge, Yuishi Iwasaki, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    Symposium on Systems Science of Bio-Navigation 2018  2018.9 

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    Event date： 2018.9

    Language：Japanese  

    Country：Japan  

  • Molecular genetic analysis of gene mutations that inhibit the forgetting of olfactory adaptation regardless of food condition International conference

    Soyoka Tanaka, Mary Arai, Takeshi Ishihara

    The 8th Asia Pacific C.elegans Meeting  2018.7 

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    Event date： 2018.7

    Language：English  

    Country：Korea, Republic of  

  • Analyzing whole neural activities to elucidate the mechanisms underlying sensory integration International conference

    Yuko Murakami, Suzu Oe, Kawahara Yuki, Takumi Katsume, Takayuki Teramoto, Yu Toyoshima, Terumasa Tokunaga, Osamu Hirose, Wu Stephan, Jang Moon-Song, Hirofumi Sato, Sayuri Kuge, Yuishi Iwasaki, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    The 8th Asia Pacific C.elegans Meeting  2018.7 

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    Event date： 2018.7

    Language：English  

    Country：Korea, Republic of  

  • Gonadal maturation changes chemotaxis behavior and neural processing in the olfactory circuit through the function of a guanylyl cyclase, GCY-28. International conference

    Manabi Fujiwara, Hiroshi wada, Takeshi Ishihara

    The 8th Asia Pacific C.elegans Meeting  2018.7 

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    Event date： 2018.7

    Language：English  

    Country：Korea, Republic of  

  • C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    第41回日本神経科学大会  2018.7 

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    Event date： 2018.7 - 2018.1

    Language：Japanese  

    Country：Japan  

  • 感覚統合のメカニズム

    村上 悠子、大江 紗、勝目 拓海、寺本 孝行、豊島 有、徳永 旭将、広瀬 修、Stephan Wu、Song Jang Moon、佐藤 博文、久下 小百合、岩崎 唯史、吉田 亮、飯野 雄一、石原 健

    第41回日本神経科学大会  2018.7 

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    Event date： 2018.7 - 2018.1

    Language：Japanese  

    Country：Japan  

  • 線虫を用いた分子遺伝学的解析による忘却機構の解明

    田中 想世花、新井 美存、石原 健

    第41回日本神経科学大会  2018.7 

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    Event date： 2018.7 - 2018.1

    Language：Japanese  

    Country：Japan  

  • Cellular analysis in forgetting of an olfactory memory in Caenorhabditis elegans

    Jamine H Teo、Tomohiro Kitazono、Takeshi Ishihara

    第41回日本神経科学大会  2018.7 

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    Event date： 2018.7 - 2018.1

    Language：Japanese  

    Country：Japan  

  • 線虫C. elegansの嗅覚回路におけるPKGを介した情報処理機構の解析

    日野 喬央、藤原 学、石原 健

    第41回日本神経科学大会  2018.7 

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    Event date： 2018.7 - 2018.1

    Language：Japanese  

    Country：Japan  

  • C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    学会  2017.12 

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    Event date： 2017.12

    Language：Japanese  

    Venue：神戸ポートアイランド   Country：Japan  

  • 単一ニューロンにおけるCa2+ ダイナミクス

    久下 小百合、寺本 孝行、徳永 旭将、石原 健

    学会  2017.12 

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    Event date： 2017.12

    Language：Japanese  

    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegansにおいて、記憶の忘却は、感覚応答をコントロールを介して、複数のシグナル伝達経路により、協調的・時期特異的に行われる

    北園 智弘、久下 小百合、井上 明俊、藤原 学、石原 健

    学会  2017.12 

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    Event date： 2017.12

    Language：Japanese  

    Venue：神戸ポートアイランド   Country：Japan  

  • C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    学会  2017.12 

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    Event date： 2017.12

    Language：Japanese  

    Venue：神戸ポートアイランド   Country：Japan  

  • Cellular and molecular analyses in forgetting of an olfactory memory in C. elegans

    Jamine H Teo、Tomohiro Kitazono、Takeshi Ishihara

    その他  2017.7 

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    Event date： 2017.7

    Language：English  

    Venue：幕張メッセ   Country：Japan  

  • 抑制性神経活動を検出する消光型蛍光カルシウムプローブタンパク質

    久下 小百合、西原 知伸、松田 知己、寺本 孝行、永井 健治、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫C. elegansにおいて、嗅覚順応の忘却は複数のシグナル伝達経路による感覚応答の調節により、協調的・時間的に制御される

    北園 智弘、久下 小百合、井上 明俊、藤原 学、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫のブタノンエンハンスメントの忘却のメカニズム

    岩瀬 なみ、猿渡 悦子、藤原 学、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • モノアミン神経伝達物質が線虫の嗅覚順応の忘却に与える影響

    高橋 龍、新井 美存、北園 智弘、藤原 学、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 成長に伴う行動変化の役割におけるフェロモンの役割

    和田 寛史

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫C. elegansの成長にともなう化学走性変化を制御する神経機構の解析

    日野 喬央、藤原 学、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫の全脳イメージングによる行動を制御する情報処理機構の解析

    大江 紗、勝目 拓海、寺本 孝行、豊島 有、徳永 旭将、Wu Stephan、広瀬 修、Moon-Sun Jang、佐藤 博文、滝沢 拓己、久下 小百合、岩崎 唯史、吉田 亮、飯野 雄一、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫C. elegansの成長に伴う行動変化とその神経回路基盤

    藤原 学、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • 線虫C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    その他  2017.7 

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    Event date： 2017.7

    Language：Japanese  

    Venue：幕張メッセ   Country：Japan  

  • The role of pheromones in behavioral changes during development of Caenorhabditis elegans. International conference

    H. Wada, R.A. Butcher, M Fujiwara, T Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • An inverse-type of fluorescent Ca2+ indicator for detecting neuronal inhibition International conference

    Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Takayuki Teramoto, Takeharu Nagai and Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Mechanisms of holding memory of butanone enhancement of C. elegans International conference

    N. Iwase, E. Sawatari, M. Fujiwara, T. Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Gonadal maturation changes chemotaxis behavior and neural processing in the olfactory circuit through the function of a guanylyl cyclase, GCY-28 International conference

    Manabi Fujiwara, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Analyses of the mechanisms of information processing controlling behavior　by whole-brain imaging in?C.?elegans. International conference

    Suzu Oe, Yuko Murakami, Takumi Katsume, Takayuki Teramoto, Terumasa Tokunaga, Yu Toyoshima, Wu Stephan, Osamu hirose, Jang Moon-Sung, Hirofumi Sato, Hiroki Takizawa, Sayuri Kuge, Yuishi Iwasaki, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Analysis of the regulation of forgetting by the food signals in the olfactory learning of C. elegans. International conference

    Mary Arai, Akitoshi Inoue, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Analyses of the molecular mechanism regulating developmental change in odor preference of C. elegans International conference

    Takahiro Hino, Manabi Fujiwara, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Analyses in forgetting of an olfactory memory in C. elegans International conference

    Jamine H. Teo, Tomohiro Kitazono, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • Effects of monoamine neurotransmitters on forgetting of olfactory adaptation in C. elegans International conference

    Ryo Takahashi, Mary Arai, Tomohiro Kitazono, Manabi Fujiwara, Takeshi Ishihara

    学会  2017.6 

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    Event date： 2017.6

    Language：English  

    Venue：University of California, Los Angels  

  • 線虫の中枢神経系全体のカルシウムイメージングによる神経回路メカニズムの解析

    石原健、寺本孝行、豊島有、徳永旭将、ステファン・ウー、広瀬修、大江紗、ジャン・ムンソン、佐藤博文、滝沢拓己、久下小百合、岩崎唯史、吉田亮、飯野雄一

    シンポジウム  2017.3 

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    Event date： 2017.3

    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：理化学研究所　生命システム研究センター   Country：Japan  

  • Neuronal circuitry for normal forgetting of an olfactory memory in C. elegans

    Jamine H. Teo、Tomohiro Kitazono、石原 健

    学会  2016.12 

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    Event date： 2016.11 - 2016.12

    Language：English  

    Venue：パシフィコ横浜   Country：Japan  

  • 神経活動の興奮と抑制を同時に測定するためのインバースタイプのカルシウムプローブの開発

    久下 小百合、西原 知伸、高橋 謙次、松田 知己、古家 博信、寺本 孝行、永井 健治、石原 健

    学会  2016.11 

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    Event date： 2016.11 - 2016.12

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    学会  2016.12 

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    Event date： 2016.11 - 2016.12

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫C. elegansの頭部神経系全体のGCaMP6fを用いた活動解析

    大江 紗、寺本 孝行、徳永 旭将、広瀬 修、豊島 有、久下 小百合、飯野 雄一、吉田 亮、石原 健

    学会  2016.12 

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    Event date： 2016.11 - 2016.12

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫C. elegansを用いた成長にともなう化学走性変化の制御機構の解析

    日野 喬央、藤原 学、石原 健

    学会  2016.9 

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    Event date： 2016.9

    Language：Japanese  

    Venue：日本大学国際関係学部三島駅北口校舎   Country：Japan  

  • C. elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井 美存、井上 明俊、石原 健

    学会  2016.9 

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    Event date： 2016.9

    Language：Japanese  

    Venue：日本大学国際関係学部三島駅北口校舎   Country：Japan  

  • Whole brain imaging reveals the roles of gap junctions for the synchronized Invited International conference

    Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English   Presentation type：Symposium, workshop panel (public)  

    Venue：Nagoya University   Country：Japan  

  • Gonadal maturation changes chemotaxis behavior and neural processing in the olfactory circuit of C. elegans International conference

    Manabi Fujiwara, Itaru Aoyama, Takahiro Hino, Takayuki Teramoto, Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • The novel components regulating forgetting of the olfactory adaptation at the downstream of the TIR-1-JNK-1 pathway International conference

    Tomohiro Kitazono

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • An inverse-type fluorescent Ca2+ indicator for detecting neuronal inhibition International conference

    Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Hironobu Furuie, Takayuki Teramoto, Takeharu Nagai, Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • Analyses of the regulation of forgetting by the food signals in the olfactory learning of C. elegans International conference

    Mary Arai, Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • The change of odor preference over development in C. elegans International conference

    Takahiro Hino, Manabi Fujiwara, Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • Analyses of the neuronal activities of the central nervous system by GCaMP6f in C. elegans. International conference

    Suzu Oe

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • AIA interneurons are required for normal forgetting of an olfactory memory International conference

    Jamine H. Teo, Tomohiro Kitazono, Takeshi Ishihara

    学会  2016.7 

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    Event date： 2016.7

    Language：English  

    Venue：Nagoya University   Country：Japan  

  • 線虫C. elegansの神経活動変化のイメージング解析

    青山 到、藤原 学、石原 健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 線虫C. elegansの頭部神経系全体のGCaMP6fを用いた活動解析

    大江 紗、寺本 孝行、徳永 旭将、広瀬 修、豊島 有、久下 小百合、飯野 雄一、吉田 亮、石原 健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 線虫C.elegansの嗅覚学習をモデルとした餌シグナルを介した忘却の制御機構の解析

    新井　美存、石原　健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 線虫C. elegansのAWC受容性の匂い物質に対する嗅覚順応の記憶の忘却機構に異常を持つ変異体の探索

    竹本 怜央、北園 智弘、井上 明俊、石原 健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 抑制性神経活動を検出する消光型蛍光カルシウムプローブタンパク質

    久下　小百合、西原　知伸、松田　知己、古谷　博信、寺本　孝行、永井　健治、石原　健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 線虫C. elegansにおける嗅覚順応の記憶の忘却を制御する新規因子の解析

    北園 智弘、桧垣 早希、井上 明俊、石原 健

    学会  2015.12 

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    Event date： 2015.12

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • Downstream signaling factors of the TIR-1-JNK-1 pathway for forgetting in C.elegans.

    北園　智弘

    研究会-シンポジウム  2015.11 

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    Event date： 2015.11

    Venue：京都ガーデンパレス、京都大学　芝蘭会館   Country：Japan  

  • Analyses of the regulation of forgetting by the food signals in the olfactory learning of C. elegans

    新井　美存、石原　健

    研究会-シンポジウム  2015.11 

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    Event date： 2015.11

    Venue：京都ガーデンパレス、京都大学　芝蘭会館   Country：Japan  

  • Whole-brain Ca2+ imaging of C. elegans reveals the multi-neuronal dynamics that are coordinated by global synaptic connectivity. International conference

    Takayuki Teramoto, Terumasa Tokunaga, Osamu Hirose, Yu Toyoshima, Yuichi Iino, Ryo Yoshida, and Takeshi Ishihara

    シンポジウム  2015.11 

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    Event date： 2015.11

    Language：English  

    Venue：東京大学   Country：Japan  

  • Whole-brain Ca2+ imaging of C. elegans to explore the neuronal mechanisms for behavioral choice. Invited International conference

    Takayuki Teramoto, Terumasa Tokunaga, Osamu Hirose, Yu Toyoshima, Yuichi Iino, Ryo Yoshida, and Takeshi Ishihara

    シンポジウム  2015.10 

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    Event date： 2015.10 - 2015.11

    Language：English  

    Venue：東京大学   Country：Japan  

  • 線虫C.elegansの成長にともなう化学走性変化とその制御機構の解析

    日野　喬央、藤原　学、　石原　健

    その他  2015.7 

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    Event date： 2015.7

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • Whole-brain imaging of C. elegans reveals multi-neuronal dynamics under non-stimulus condition. Invited

    Takayuki Teramoto, Terumasa Tokunaga, Osamu Hirose, Yu Toyoshima, Yuichi Iino, Ryo Yoshida, and Takeshi Ishihara

    シンポジウム  2015.7 

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    Event date： 2015.7

    Venue：神戸国際会議場、神戸国際展示場   Country：Japan  

  • 線虫C. elegansにおいて、嗅覚順応の忘却を制御するTIR-1-JNK-1経路の下流制御因子

    北園智弘、桧垣早希、井上明俊、石原健

    その他  2015.7 

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    Event date： 2015.7

    Language：Japanese  

    Venue：神戸国際展示場   Country：Japan  

  • 線虫の感覚行動のライフサイクルにおける変化

    藤原学、佐藤則子、丸山新一、石原健

    その他  2015.7 

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    Event date： 2015.7

    Language：Japanese  

    Venue：神戸国際会議場   Country：Japan  

  • Screening mutants defective in the forgetting of the olfactory adaptation of the odorants sensed by AWC neurons International conference

    Reo Takemoto, Tomohiro Kitazono, Akitoshi Inoue, Takeshi Ishihara.

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • Whole-brain imaging at cellular resolution reveals multi-neuronal dynamics under non-stimulus condition. International conference

    Takayuki Teramoto, Terumasa Tokunaga, Osamu Hirose, Yu Toyoshima, Yuichi Iino, Ryo Yoshida, and Takeshi Ishihara

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • The germline growth affects the neuronal circuits and the behavioral patterns of worms. International conference

    Manabi Fujiwara, Itaru Aoyama, Shinichi Maruyama, Takeshi Ishihara

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • A quenching-type of fluorescent Ca2+ indicator for detecting neuronal inhibition International conference

    Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Hironobu Furuie, Takayuki Teramoto, Takeharu Nagai and Takeshi Ishihara

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • Analysis of downstream regulatory components of the TIR-1-JNK-1 pathway for forgetting of the olfactory adaptation in C. elegans International conference

    Tomohiro Kitazono

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • Odor preference is changed over development in C. elegans International conference

    Takahiro Hino, Manabi Fujiwara, Takeshi Ishihara

    学会  2015.6 

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    Event date： 2015.6

    Language：English  

    Venue：University of California, LA   Country：United States  

  • Whole-brain imaging of C. elegans reveals multi-neuronal dynamics under non-stimulus condition. International conference

    Takayuki Teramoto, Terumasa Tokunaga, Osamu　Hirose, Yu Toyoshima, Yuichi Iino, Ryo Yoshida, Takeshi Ishihara

    Cold Spring Harbor Laboratory Meeting Wiring the Brain  2015.3 

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    Event date： 2015.3

    Language：English  

    Venue：Cold Spring Harbor Laboratory, Cold Spring Harbor, NY   Country：United States  

  • Analyses of the developmental changes in the odor preference of C. elegans International conference

    Takahiro Hino, Manabi Fujiwara, Takeshi Ishihara

    Cold Spring Harbor Laboratory Meeting Wiring the Brain  2015.3 

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    Event date： 2015.3

    Language：English  

    Venue：Cold Spring Harbor Laboratory, Cold Spring Harbor, NY   Country：United States  

  • 線虫中枢神経系のまるごと計測および定量解析にむけた取り組み Invited

    寺本　孝行, 吉田　亮

    定量生物の会　第７回年会  2015.1 

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    Event date： 2015.1

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：九州大学　筑紫キャンパス   Country：Japan  

  • 4-D imaging of neuronal activities in a local circuit for C. elegans behavioral choice

    寺本　孝行, 石原 健

    包括型脳科学研究推進支援ネットワーク　2014年度シンポジウム　「予測と意思決定」領域会議  2014.12 

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    Event date： 2014.12

    Language：English   Presentation type：Oral presentation (general)  

    Venue：東京医科歯科大学   Country：Japan  

  • 線虫、C.elegansの単一神経細胞におけるカルシウムダイナミクス

    久下　小百合, 寺本　孝行, 石原 健

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫C. elegansの成長に伴う神経活動変化のイメージング解析

    青山　到, 藤原 学, 石原 健

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫C. elegansを用いた成長にともなう行動パターン変化の制御機構の解析

    日野　喬央, 藤原 学, 石原 健

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 嗅覚順応の記憶の忘却を抑制的に制御する分子機構の解析

    伊藤　昂洋, 石原 健

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫の全中枢神経のCa2+イメージングによる刺激に対する応答と無刺激時における神経活動の計測

    寺本　孝行, 久下　小百合, 石原 健, 徳永　旭将, 吉田　亮, 広瀬　修, 豊島　有, 飯野　雄一

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫の感覚行動のライフサイクルにおける変化とその制御機構

    藤原 学, 佐藤　則子, 丸山　新一, 石原 健

    第37回日本分子生物学会年会  2014.11 

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    Event date： 2014.11

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 線虫C. elegansの全中枢神経のCa2+イメージングによる刺激に対する応答と無刺激時における神経活動の計測

    寺本　孝行, 久下　小百合, 石原 健, 徳永　旭将, 吉田　亮, 広瀬　修, 豊島　有, 飯野　雄一

    JST/CREST第3回領域会議  2014.10 

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    Event date： 2014.10

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：沖縄科学技術大学院大学（OIST）   Country：Japan  

  • Active forgetting of the olfactory memory in C. elegans. Invited International conference

    Takeshi Ishihara, Akitoshi Inoue, Tomohiro Kitazono, Etsuko Sawatari, Manabi Fujiwara, Takayuki Teramoto

    Neurobiology:Diverse Species & Conserved Principles  2014.9 

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    Event date： 2014.9

    Language：English   Presentation type：Symposium, workshop panel (public)  

    Venue：Cold Spring Harbor Asia Conference Centre (Suzhou)   Country：China  

  • 線虫C.elegansにおいて、忘却を制御するTIR-1/JNK-1経路の下流因子の解析

    北園智弘, 井上明俊, 石原 健

    第37回　日本神経科学大会  2014.9 

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    Event date： 2014.9

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • 嗅覚順応の忘却を抑制的に制御する分子機構の解明

    伊藤　昂洋, 北園　智弘, 石原 健

    第37回　日本神経科学大会  2014.9 

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    Event date： 2014.9

    Language：Japanese  

    Venue：パシフィコ横浜   Country：Japan  

  • Analyses of molecular mechanisms that negatively regulate forgetting of olfactory adaptation. International conference

    Takahiro Ito, Tomohiro Kitazono, Takeshi Ishihara

    C. elegans Development, Cell Biology and Gene Expression Meeting in associated with The 6th Asia-Pacific C. elegans meeting  2014.7 

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    Event date： 2014.7

    Language：English  

    Venue：Nara prefectural new public hall   Country：Japan  

  • How does the animal change its behavioral patterns during growth? International conference

    Manabi Fujiwara, Noriko Sato, Shinichi Maruyama, Takeshi Ishihara

    C. elegans Development, Cell Biology and Gene Expression Meeting in associated with The 6th Asia-Pacific C. elegans meeting  2014.7 

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    Event date： 2014.7

    Language：English   Presentation type：Oral presentation (general)  

    Venue：Nara prefectural new public hall   Country：Japan  

  • Analyses of the developmental changes in the odor preference of C. elegans International conference

    Takahiro Hino, Manabi Fujiwara, Takeshi Ishihara

    C. elegans Development, Cell Biology and Gene Expression Meeting in associated with The 6th Asia-Pacific C. elegans meeting  2014.7 

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    Event date： 2014.7

    Language：English  

    Venue：Nara prefectural new public hall   Country：Japan  

  • Tracking og Ca2+ dynamics in a whole single neuron International conference

    Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara

    C. elegans Neuro 2014  2014.7 

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    Event date： 2014.7

    Language：English  

    Venue：University of Wisconsin - Madison   Country：United States  

  • 4-D imaging of neuronal activities in the whole central nervous system visualizes correlative patterns between multiple neurons.

    Takayuki Teramoto, Yu Toyoshima, Terumasa Tokunaga, Ryo Yoshida, Yuichi Iino, Takeshi Ishihara

    C. elegans Neuro 2014  2014.7 

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    Event date： 2014.7

    Language：English  

    Venue：University of Wisconsin - Madison   Country：United States  

  • Downstream regulatory components of the TIR-1/JNK-1 pathway for forgetting in C. elegans. International conference

    Tomohiro Kitazono, Akitoshi Inoue, Takeshi Ishihara

    C. elegans Neuro 2014  2014.7 

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    Event date： 2014.7

    Language：English  

    Venue：University of Wisconsin - Madison   Country：United States  

  • The downstream components of the TIR-1/JNK-1 pathway for forgetting in C. elegans

    北園智弘, 井上明俊, 石原 健

    新学術領域「多様性から明らかにする記憶ダイナミズムの共通原理」班会議  2014.6 

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    Event date： 2014.6

    Language：Japanese  

    Venue：シェラトンホテル札幌   Country：Japan  

  • The downstream components of the TIR-1/JNK-1 pathway for forgetting in C. elegans

    北園智弘, 井上明俊, 石原 健

    新学術領域「多様性から明らかにする記憶ダイナミズムの共通原理」班会議  2014.6 

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    Event date： 2014.6

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：シェラトンホテル札幌   Country：Japan  

  • In vivo 4-D Ca2+ imaging of multi-neuronal activities in a local circuit for C. elegans decision-making Invited

    寺本 孝行, 石原 健

    新学術領域研究「予測と意思決定」第７回領域会議  2014.6 

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    Event date： 2014.6

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：九州工業大学   Country：Japan  

  • 線虫C. elegansにおけるcGMP依存性タンパク質キナーゼ EGL-4による特定の匂いへの走性制御機構の解析

    有井 照剛、藤原 学、石原 健

    第34回日本分子生物学会  2011.12 

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    Event date： 2011.12

    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • 4D in vivo Ca2+ imaging of the C. elegans neural network Invited

    寺本 孝行、石原 健

    第34回日本分子生物学会  2011.12 

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    Event date： 2011.12

    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • 線虫C. elegansにおける感覚情報の統合の分子メカニズムの解析

    山本 悠太、新海 陽一、猿渡 悦子、寺本 孝行、石原 健

    第34回日本分子生物学会  2011.12 

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    Event date： 2011.12

    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • Regulatory mechanisms of sensory integration for behavioral choice in C. elegans Invited

    石原健、新海陽一、山本悠太、寺本孝行

    第34回日本神経科学大会  2011.9 

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    Event date： 2011.9

    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • C.ｅｌｅｇａｎｓ神経ネットワークの４次元Ｃａ２＋イメージング

    寺本孝行、石原健

    第34回日本神経科学大会  2011.9 

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    Event date： 2011.9

    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • 線虫C. elegansにおける感覚情報の統合の分子メカニズムの解析

    山本 悠太、新海 陽一、寺本 孝行、石原 健

    第34回日本神経科学大会  2011.9 

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    Event date： 2011.9

    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • Chemotaxis behavior is regulated by germline in C. elegans International conference

    Fujiwara Mnabi, Takeshi Ishihara

    １８ｔｈ　International　C.eｌｅｇａｎｓ　Meeting  2011.6 

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    Event date： 2011.6

    Presentation type：Symposium, workshop panel (public)  

    Venue：Los Angeles U.S.A.   Country：United States  

  • Changes in responsivity of olfactory neurons to odor during olfactory adaptation and recovery in Caenorhabditis elegans International conference

    Swatari Etsuko, Takeshi Ishihara

    １８ｔｈ　International　C.eｌｅｇａｎｓ　Meeting  2011.6 

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    Event date： 2011.6

    Presentation type：Symposium, workshop panel (public)  

    Venue：Los Angeles U.S.A.   Country：United States  

  • The P38/JNK MAP kinase pathway regulates forgetting in Caenorhabditis elegans International conference

    Akitoshi Inoue, Takeshi Ishihara

    １８ｔｈ　International　C.eｌｅｇａｎｓ　Meeting  2011.6 

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    Event date： 2011.6

    Presentation type：Oral presentation (general)  

    Venue：Los Angeles U.S.A.   Country：United States  

  • Molecular and neural mechanisms for behavioral choice between two　conflicting alternatives in C. elegans Invited International conference

    石原健、新海陽一、山本悠太、寺本孝行

    The 3rd International Conference on Cognitive Neurodynamics  2011.6 

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    Event date： 2011.6

    Presentation type：Oral presentation (general)  

    Venue：北海道   Country：Japan  

  • 線虫の匂いの好みを変化させる性腺シグナルの働きと作用機構

    藤原　学、佐藤則子、石原　健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • 線虫C.elegansにおける感覚情報の統合の分子メカニズムの解析

    山本悠太、石原　健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • 線虫C. elegansの嗅覚神経におけるRasの活性化のライブイメージング

    魚住隆行、広津崇亮、寺本孝行、山田龍司、鈴木暁也、石原健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • 線虫C. elegansにおいて記憶の忘却はp38/JNK MAPキナーゼ経路により制御される

    井上明俊、石原　健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • 線虫C. elegansにおけるブタノンエンハンスメントにかかわる記憶の消去の解析

    猿渡　悦子、海江田兼次、石原　健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • 線虫C. elegansにおける嗅覚受容体の網羅的解析

    広津崇亮、桐山恵介、紙崎智子、佐藤則子、石原　健

    BMB2010・第33回日本分子生物学会  2010.12 

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    Event date： 2010.12

    Venue：神戸   Country：Japan  

  • Four-dimensional in vivo Ca2+ imaging of the C. elegans neural network International conference

    寺本　孝行、石原　健

    第16回武田科学振興財団生命科学シンポジウム  2010.11 

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    Event date： 2010.12

    Venue：東京   Country：Japan  

  • Molecular and neural mechanisms of behavioral choice in C. elegans Invited International conference

    Takeshi Ishihara

    2010.11 

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    Event date： 2010.11

    Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

  • 線虫C.elegansを用いた感覚情報の統合のメカニズムの解析

    新海陽一、山本悠太、石原　健

    Neuro 2010  2010.9 

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    Event date： 2010.9

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • The P38/JNK MAP kinase pathway regulates forgetting in Caenorhabditis elegans

    Inoue A, Ishihara T

    Neuro 2010  2010.9 

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    Event date： 2010.9

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • Neural and Behavioral Mechanisms of Response to an Odorant Depending on its Concentration International conference

    Yoshida K, Hirotsu T, Tagawa T, Oda S, Iino Y, Ishihara T.

    East Asia Worm Meeting .  2010.7 

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    Event date： 2010.7

    Presentation type：Oral presentation (general)  

    Venue：Tokyo   Country：Japan  

  • Pheromonal interactions modulate behavioral plasticity in C. elegans International conference

    Yamada K, Hirotsu T, Matsuki M, Butcher R A, Ishihara T, Clardy J, Kunitomo H, Iino Y.

    East Asia Worm Meeting  2010.7 

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    Event date： 2010.7

    Presentation type：Oral presentation (general)  

    Venue：Tokyo   Country：Japan  

  • Live imaging of Ras activity in the olfactory system in C. elegans International conference

    Uozumi T, Hirotsu T, Teramoto T, Yamada R, Suzuki A, Ishihara T.

    NEURONAL DEVELOPMENT,SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting  2010.6 

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    Event date： 2010.6

    Presentation type：Oral presentation (general)  

    Venue：Madison,USA   Country：United States  

  • The P38/JNK MAP kinase pathway regulates forgetting in Caenorhabditis elegans International conference

    Inoue A, Ishihara T

    NEURONAL DEVELOPMENT,SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting  2010.6 

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    Event date： 2010.6

    Presentation type：Oral presentation (general)  

    Venue：Madison,USA   Country：United States  

  • Ascaroside Pheromones Regulate Olfactory Plasticity through the SNET 1 Peptide International conference

    Yamada K, Hirotsu T, Matsuki M, Butcher R A, Ishihara T, Clardy J, Kunitomo H, Iino Y.

    NEURONAL DEVELOPMENT,SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting  2010.6 

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    Event date： 2010.6

    Presentation type：Oral presentation (general)  

    Venue：Madison,USA   Country：United States  

  • Neural and Behavioral Mechanisms of Response to an Odorant Depending on its Concentration International conference

    Yoshida K, Hirotsu T, Tagawa T, Oda S, Iino Y, Ishihara T.

    NEURONAL DEVELOPMENT,SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting  2010.6 

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    Event date： 2010.6

    Presentation type：Oral presentation (general)  

    Venue：Madison,USA   Country：United States  

  • 線虫の神経回路における感覚情報の統合と記憶の忘却のメカニズム Invited

    石原　健

    日本分子生物学会第10回春季シンポジウム  2010.6 

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    Event date： 2010.6

    Presentation type：Oral presentation (general)  

    Venue：宮城県松島町   Country：Japan  

  • MOLECULAR ANALYSES OF THE INTEGRATION OF TWO SENSORY　SIGNALS IN C. ELEGANS International conference

    Shinkai,Y. and Ishihara, T.

    Neuronal Circuits  2010.3 

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    Event date： 2010.3 - 2009.6

    Presentation type：Oral presentation (general)  

    Venue：Cold Spring Harbor   Country：United States  

    MOLECULAR ANALYSES OF THE INTEGRATION OF TWO SENSORY　SIGNALS IN C. ELEGANS

  • 線虫の嗅覚系におけるRasの活性化のライブイメージング

    魚住　隆行, 広津　崇亮, 山田　龍司, 鈴木　暁也、石原　健

    第32回日本分子生物学会  2009.12 

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    Event date： 2009.12

    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫を用いた記憶を忘れるメカニズムの遺伝学的解析

    井上明俊・石原　健

    第32回日本分子生物学会  2009.12 

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    Event date： 2009.12

    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

    Genetic analyses of mechanisms for memory loss in Caenorhabditis elegans

  • 線虫C.elegans　におけるブタノンエンハンスメントに関わる記憶の消去の解析

    海江田　兼次・石原　健

    第32回日本分子生物学会  2009.12 

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    Event date： 2009.12

    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

    Studies on memory decline for butanone enhancement in Caenorhabditis elegans

  • Search for the new regulators of the RNAi pathway in C. elegans

    出水田一生・藤原　学

    第32回日本分子生物学会  2009.12 

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    Event date： 2009.12

    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Live imaging of Ras activity in olfactory neurons in C. elegans.

    Hirotsu T., Yamada R., Suzuki A., Uozumi T., Ishihara T.

    International Symposium on Cellular Signaling  2009.11 

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    Event date： 2009.11

    Presentation type：Oral presentation (general)  

    Venue：筑波   Country：Japan  

  • Molecular mechanisms of sensory integration and memory loss in C. elegans International conference

    石原　健

    神経系の動作原理を明らかにするためのシステム分子行動学  2009.11 

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    Event date： 2009.11

    Presentation type：Oral presentation (general)  

    Venue：静岡   Country：Japan  

    Molecular mechanisms of sensory integration and memory loss in C. elegans

  • 線虫における嗅覚受容体遺伝子の解析

    桐山恵介・広津崇亮・紙崎智子・佐藤則子・石原健

    第3２回日本神経科学大会  2009.9 

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    Event date： 2009.9

    Presentation type：Oral presentation (general)  

    Venue：名古屋   Country：Japan  

    Analysis of putative olfactory receptor genes in C.elegans

  • 線虫の嗅覚神経におけるRasの活性のライブイメージング

    広津崇亮・山田龍司・鈴木暁也・石原健

    第3２回日本神経科学大会  2009.9 

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    Event date： 2009.9

    Presentation type：Oral presentation (general)  

    Venue：名古屋   Country：Japan  

    Live imaging of Ras activity in olfactory neurons in C.elegans

  • 線虫における記憶を忘れるメカニズムの遺伝学的解析

    井上明俊・石原健

    第3２回日本神経科学大会  2009.9 

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    Event date： 2009.9

    Presentation type：Oral presentation (general)  

    Venue：名古屋   Country：Japan  

    Genetic analyses of mechanisms for memory loss in C.elegans

  • Live imaging of Ras activity in olfactory neurons in C. elegans. International conference

    Hirotsu, T., Yamada, R., Suzuki, A. and Ishihara, T.

    17th International C.elegans Meeting  2009.6 

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    Event date： 2009.6

    Presentation type：Oral presentation (general)  

    Venue：Los Angeles   Country：United States  

  • Molecular analysis of the integration of two sensory signals in C. elegans International conference

    Shinkai,Y. and Ishihara, T.

    17th International C.elegans Meeting  2009.6 

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    Event date： 2009.6

    Presentation type：Oral presentation (general)  

    Venue：Los Angeles   Country：United States  

  • Systematic identification of specific receptors for odorants in C. elegans. International conference

    Kiriyama, K., Hirotsu, T., Kamizaki, T., Sato, N. and Ishihara,T.

    17th International C.elegans Meeting  2009.6 

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    Event date： 2009.6

    Presentation type：Oral presentation (general)  

    Venue：Los Angeles   Country：United States  

  • Chemotactic control by a germline signal in C. elegans International conference

    Fujiwara, M., Sato, N., Maruyama, S., Akamine, T. and Ishihara , T.

    17th International C.elegans Meeting  2009.6 

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    Event date： 2009.6

    Presentation type：Oral presentation (general)  

    Venue：Los Angeles   Country：United States  

  • 線虫C. elegansにおけるブタノンエンハンスメントに関わる記憶の消去の解析

    海江田兼次、石原健

    第３１回日本分子生物学会年会･第８１回日本生化学会大会合同大会  2008.12 

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    Event date： 2008.12

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫C.elegans を用いた記憶を忘れるメカニズムの遺伝的解析

    井上明俊、石原　健

    第３１回日本分子生物学会年会･第８１回日本生化学会大会合同大会  2008.12 

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    Event date： 2008.12

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫C.elegansでのCa2+イメージングによる感覚情報統合の可視化

    畑　茉容1, 横田　慎一2, 石原　健1　(1九州大学・院理・生物, 2大阪大学・院・生命機能)

    第３１回日本分子生物学会年会･第８１回日本生化学会大会合同大会  2008.12 

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    Event date： 2008.12

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫C.elegansの神経回路を介した嗅覚順応機構の分子遺伝学的解析

    前田恭介・広津崇亮・石原健

    第３１回日本分子生物学会年会･第８１回日本生化学会大会合同大会  2008.12 

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    Event date： 2008.12

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫C. elegansにおけるブタノンエンハンスメントに関わる記憶の消去の解析

    海江田兼次、石原健

    第３１回日本分子生物学会年会･第８１回日本生化学会大会合同大会  2008.12 

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    Event date： 2008.12

    Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫における感覚情報処理の分子機構 Invited

    石原　健

    第31回日本神経科学大会  2008.7 

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    Event date： 2008.7

    Presentation type：Symposium, workshop panel (public)  

    Venue：東京   Country：Japan  

    Molecular mechanisms of sensory processing in C.elegans

  • 線虫C.elegansの嗅覚応答を制御するG蛋白質シグナル

    広津崇亮、山田龍司、紙崎智子、佐藤則子、石原　健

    第31回日本神経科学大会  2008.7 

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    Event date： 2008.7

    Presentation type：Oral presentation (general)  

    Venue：東京   Country：Japan  

    G protain signaling in olfactory systems of C.elegans.

  • Molecular Mechanisms Of The Integration Of Two Sensory Signals In C.elegans. International conference

    Shinkai, Y., Tsunozaki, M., Bargmann, C. and Ishihara, T.

    NEWRONAL DEVELOPMENT, SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting #2,  2008.6 

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    Event date： 2008.6 - 2008.7

    Presentation type：Oral presentation (general)  

    Venue：Madison   Country：United States  

  • Genetic analyses of the mechanisms for forgetting in Caenorhabditis elegans. International conference

    Inoue, A. and Ishihara, T.

    2008 East Asia Worm Meeting  2008.4 

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    Event date： 2008.4

    Presentation type：Oral presentation (general)  

    Venue：上海   Country：China  

  • A receptor guanylate cyclase, GCY-28, regulates sensory integration and salt Chemotaxis learning in C.elegans. International conference

    Shinkai, Y., Tsunozaki, M., Bargmann, C., and Ishihara, T.

    2008 East Asia Worm Meeting  2008.4 

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    Event date： 2008.4

    Presentation type：Oral presentation (general)  

    Venue：上海   Country：China  

  • 線虫C. elegansにおける忘却を制御するTIR-1/JNK-1経路の下流因子の探索

    北園智弘, 井上明俊, 石原 健

    第36回日本分子生物学会年会  2013.12 

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    Language：Japanese  

    Venue：京都   Country：Japan  

  • A secretory protien OSM-7 is involved in not only chemotaxis buto also resistance to high osmolarity International conference

    Mase K., Ohshima Y., Ishihara T. and Koga M.

    East Asia C. elegans Meeting  2004.6 

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    Venue：淡路夢舞台国際会議場   Country：Japan  

  • MPK-1 MAP kinase regulates the behavioral plasticity under the condition of food-salt coexistence International conference

    Emoto Y., Ohshima Y., Ishihara T. and Koga M.

    East Asia C. elegans Meeting  2004.6 

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    Venue：淡路夢舞台国際会議場   Country：Japan  

  • cGMP-signaling for regulation of body size in C.elegans International conference

    M.Fujiwara, H. Ohta, Y. Ohshima, S.L. Nclatire, T. Ishihara

    East Asia C. elegans Meeting  2004.6 

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    Venue：淡路夢舞台国際会議場   Country：Japan  

  • Receptor tyrosine kinase, SCD-2, regulates sensory integration and behavioral plasticity International conference

    Takeshi Ishihara, Yuichi Iino, Isao Katsura

    East Asia C. elegans Meeting  2004.6 

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    Venue：淡路夢舞台国際会議場   Country：Japan  

  • A secretory protein OSM-7 expressed in hypodermis may regulate chemotaxis to sodium ion and resistance to high osmolariy. International conference

    Mase K., Ohshima Y., Ishihara T. and Koga M.

    West Coast Worm Meeting 2004  2004.8 

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    Venue：University of California, Santa Barbara   Country：United States  

  • cGMP-signaling for regulation of body size in C. elegans International conference

    Fujiwara M, Ohta H, Ohsima Y, McIntire SL, Ishihara T

    West Coast Worm Meeting 2004  2004.8 

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    Venue：University of California, Santa Barbara   Country：United States  

  • RECEPTOR TYROSINE KINASE, SCD-2, REGULATES SENSORY INTEGRATION AND LEARNING IN C. ELEGANS. International conference

    Takeshi Ishihara Yuichi Iino, and Isao Katsura

    Neuronal Plasticity Cold Spring Harbor Symposium  2004.9 

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    Presentation type：Symposium, workshop panel (public)  

    Venue：Cold Spring Harbor   Country：United States  

    （口頭発表）

  • 線虫C. elegans のDBL-1/TGF-β信号伝達系に関する体の大きさの制御機構の解析

    太田博允、藤原 学、大島靖美、石原 健

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • MAPキナーゼBMK1/ERK5ホモログSMA-5 によるC. elegansの個体の大きさの制御

    渡邉直春、石原 健、大島靖美

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegans の分泌タンパク質 OSM-7 は感覚受容と高浸透圧への耐性を制御する

    間瀬慶子、大島靖美、石原 健、古賀誠人

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegans においてMAP-1 MAPキナーゼは餌存在下でのNaclに対する感覚順応を調節する

    江本 由香子、大島 靖美、石原 健、古賀 誠人

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • C. elegans の餌に関わる情報処理に異常がある変異体の解析

    村山　孝、間瀬　慶子、大島　靖美、石原　健、古賀　誠人

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegans の感覚情報をもとにした体のサイズの制御機構

    藤原　学、Steven Mclintire、大島靖美、石原　健,

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegansにおける感覚情報の統合と連合学習の分子機構

    石原　健、池田　大祐、田畑　孝、飯野　雄一、桂　勲

    第27回日本分子生物学会年会  2004.12 

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    Venue：神戸ポートアイランド   Country：Japan  

  • 線虫C. elegansにおける感覚情報処理の分子機構 Invited

    石原　健

    平成15年度生理学研究所研究所シナプス研究会  2004.12 

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    Venue：岡崎市   Country：Japan  

  • Ras-MAPK SIGNALING PATHWAY REGULATES SUPPRESSION OF NaCl ADAPTATION BY FOOD IN C. ELEGANS International conference

    Emoto Y., Ohshima Y., Ishihara T. and Koga M.

    Cold Spring Harbor Laboratory Meetings & Courses LEARNING & MEMORY  2005.4 

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    Venue：Cold Spring Harbor   Country：United States  

  • OSM-7 localized in cuticles affects resistance to environmental stress. International conference

    K. Mase, A. Onodera, S. Yanase, K. Gengyo-Ando, S. Mitani, N. Ishii, Y. Ohshima,

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • Identification of new genes involved in body size regulation by screen utilizing lon-1 promoter gfp fusion International conference

    H. Ohta, M. Fujiwara, Y. Ohshimra and T. Ishihara

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • Ras-MAPK signaling pathway regulates suppression of NaCl adaptation by food in C. elegans. International conference

    Y. Emoto, Y. Ohshima, T. Ishihara and M. Koga :

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • The Ras-MAPK pathway controls neural circuit-dependent odor adaptation by regulating localization of glutamate receptors in C. elegans International conference

    T. Hirotsu, E. Nishida and Y. Iino

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • Sensory regulation of fat storage and body growth in C.elegans International conference

    M. Fujiwara, Y. Ohshima, S. L. McIntire and T. Ishihara

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • Receptor tyrosine kinaze, SCD-2, regulates sensory integration and learning in C. elegans. International conference

    T. Ishihara, T. Tabata, D. D. Ikeda, Y. Iino and I. Katsura

    15th Biennial International C.elegans  2005.6 

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    Venue：University of California,Los Angeles   Country：United States  

  • Ras-MAPK signaling pathway regulates suppression of NaCl adaptation by food in C. elegans　 Ras-MAPKシグナル伝達経路は線虫C. elegans の NaCl への順応の餌による制御を調節する。

    江本 由香子・大島 靖美・石原　健・古賀 誠人

    第２８回日本神経科学大会  2005.7 

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    Country：Japan  

  • C. エレガンスの体のサイズはcGMP信号伝達系を介した感覚情報によって調節される Sensory information through cGMP signaling controls the body growth of C. elegans.

    藤原　学、Steven McIntire、大島靖美、石原　健

    第２８回日本神経科学大会  2005.7 

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    Presentation type：Symposium, workshop panel (public)  

    Venue：横浜   Country：Japan  

  • 線虫C. elegansの受容体チロシンキナーゼSCD-2による感覚情報の統合と学習の制御 Receptor tyrosine kinase, scd-2, regulates sensory integration and learning in C. elegans.

    石原　健、田畑　孝、池田　大祐、飯野　雄一、桂　勲

    第２８回日本神経科学大会、  2005.7 

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    Venue：横浜   Country：Japan  

  • 線虫C. elegansの嗅覚順応のメカニズム：Ras-MAPK経路によるグルタミン酸受容体の制御

    広津　崇亮、石原　健、西田　栄介、飯野　雄一

    日本遺伝学会　第77回大会  2005.9 

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    Venue：東京   Country：Japan  

  • 線虫 C. elegans における体の大きさの制御に関する新規遺伝子の同定

    太田　博允、藤原　学、大島　靖美、石原　健

    日本遺伝学会　第77回大会  2005.9 

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    Venue：東京   Country：Japan  

  • 神経回路における感覚情報統合と連合学習の制御に関わる分子機構の解析

    石原　健

    特定領域研究「統合脳」冬のシンポジウム  2005.12 

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    Venue：東京都   Country：Japan  

  • 線虫C. elegansの個体の大きさを制御するcGMP依存性タンパク質リン酸化酵素EGL-4の上流制御因子の解析

    宮本　竜太、村永　洋一、藤原　学、石原　健

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡   Country：Japan  

  • 線虫C. elegansにおける感覚情報統合に関わる受容体チロシンキナーゼSCD-2の機能解析

    田畑 孝, 村山 孝, 池田 大祐, 飯野 雄一, 桂 勲, 石原 健

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡市   Country：Japan  

  • 線虫における感覚情報の統合を制御する新規分子の探索

    新海 陽一、石原 健

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡市   Country：Japan  

  • 線虫C. elegansにおける高浸透圧ストレスや酸化ストレスに対する応答にクチクラ層の構成成分OSM-7が関与する

    間瀬 慶子、小野寺 章、梁瀬 澄乃、安藤 恵子、三谷 昌平、大島 靖美、桂 勲、石井 直明、石原 健、古賀 誠人

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡   Country：Japan  

  • 線虫 C. elegans のDBL-1/TGF-β信号伝達系が関与する体の大きさの制御機構の解析

    太田 博允、藤原 学、大島 靖美、石原 健

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡市   Country：Japan  

  • 線虫C. elegansの神経回路レベルで成立する嗅覚順応の分子メカニズム

    広津 崇亮、石原 健、西田 栄介、飯野 雄一

    第２８回分子生物学会年会  2005.12 

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    Venue：福岡   Country：Japan  

  • 線虫C. elegansにおける感覚情報の統合と学習の分子機構 Invited

    石原　健

    日本動物学会九州支部・日本植物学会九州支部・日本生態学会九州地区・  2005.12 

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    Presentation type：Oral presentation (general)  

    Venue：福岡   Country：Japan  

  • A genetic screen to identify novel genes regulating integration of sensory signals in C. elegans International conference

    Yoichi Shinkai, Takeshi Ishihara

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  2006.6 

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    Venue：京都府   Country：Japan  

  • A cuticle component OSM-7 regulates responses to osmotic oxidative stresses in C.elegans International conference

    Keiko MASE, Akira ONODERA, Sumino YANASE, Keiko GENGYO-ANDO, Shohei MITANI, Yasumi OHSHIMA, Isao KATSURA, Naoaki ISHII, Takeshi ISHIHARA, Makoto KOGA,

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  2006.6 

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    Venue：京都府   Country：Japan  

  • Screening for novel body-size regulators in C. elegans International conference

    Hiromitsu Ohta, Manabi Fujiwara, Yasumi Ohshima, Takeshi Ishihara

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  2006.6 

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    Venue：京都府   Country：Japan  

  • MPK-1 MAP kinase regulates NaCl learning in C. elegans International conference

    Yukako EMOTO, Yasumi OHSHIMA, Takeshi ISHIHARA, Makoto KOGA

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  2006.6 

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    Venue：京都府   Country：Japan  

  • Sensory information through cGMP signaling controls the energy homeostasis of C.elegans. International conference

    Manabi Fujiwara , Takeshi Ishihara

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  2006.6 

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    Venue：京都府   Country：Japan  

    第20回国際生化学・分子生物学会議/第11回アジア・オセアニア生化学者・分子生物学者連合会議/第79回日本生化学会大会、第29回日本分子生物学会年会

  • A genetic screen to identify novel genes regulating integration of sensory signals in C. elegans International conference

    Shinkai Y., Ishihara T.

    2006 NEURONAL DEVELOPMENT, SYNAPTIC FUNCTION & BEHAVIOR C.elegans Topic Meeting  2006.7 

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    Presentation type：Oral presentation (general)  

    Country：United States  

  • Identifiying genes required for the integration of sensory signals in C. elegans International conference

    Shinkai Y., Ishihara T.

    2006 East Asia C.elegans Meeting  2006.11 

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    Presentation type：Oral presentation (general)  

    Country：Korea, Republic of  

  • SCD-2, a receptor tyrosine kinase, function in interneurons to regulate sensory integration and learning in C. elegans International conference

    Tabata T., Ikeda D., Iino Y., Katsura I.., Murayama T., Ishihara T

    2006 East Asia C.elegans Meeting  2006.11 

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    Presentation type：Oral presentation (general)  

    Country：Korea, Republic of  

  • PDE-2, a cyclic nucleotide phosphodiesterase, controls EGL-4 activity to regulate the body size of C. elegans International conference

    Miyamoto R., Muranaga Y., Koga M., Fujiwara M., Ishihara T.

    2006 East Asia C.elegans Meeting  2006.11 

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    Presentation type：Oral presentation (general)  

    Country：Korea, Republic of  

  • Activity of MPK-1 MAP kinase regulates gustatory adaptation in C.elegans. International conference

    Emoto, Y., Oshima ,Y., Ishihara, T. , Koga ,M.

    The 16th International C.elegans meeting  2007.6 

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    Presentation type：Oral presentation (general)  

    Country：United States  

  • ADBP-1, a novel protein interacting with an RNA editing-enzyme ADR-2, modulates the Somatic expression of transgenes. International conference

    Ohta, H., Fujiwara, M. , Ishihara ,T.

    The 16th International C.elegans meeting  2007.6 

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    Presentation type：Oral presentation (general)  

    Country：United States  

  • Genetic analysis of the sensory integration process in the neuronal circuit. International conference

    Shinkai ,Y .and Ishihara, T.

    The 16th International C.elegans meeting  2007.6 

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    Presentation type：Oral presentation (general)  

    Country：United States  

  • Genetic analyses of mechanism for memory erasing in Caenorhaditis elegans. International conference

    Inoue, A.and Ishihara, T.

    The 16th International C.elegans meeting  2007.6 

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    Presentation type：Oral presentation (general)  

    Country：United States  

  • Activity of MPK-1 MAP kinase regulates gustatory adaptation in C.elegans.

    Emoto,Y., Ohshima, Y., Ishihara, T.and Koga, M.

    第30回日本神経科学大会  2007.9 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Genetic analyses of the sensory integration process in the neuronal circuits in Caenorhaditis elegans.

    Shinkai, Y. and Ishihara, T.

    第30回日本神経科学大会  2007.9 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Genetic analyses of mechanism for memory decline in Caenorhaditis elegans.

    Inoue, A .and Ishihara,T.

    第30回日本神経科学大会  2007.9 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Olfactory processing in C.elegans nervous sysytem. Invited International conference

    石原　健

    The 5th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception.  2007.11 

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    Presentation type：Oral presentation (general)  

    Venue：福岡   Country：Japan  

  • ADBP-1, a novel protein interacting with an RNA editing-enzyme ADR-2, modulates the somatic expression of transgenes.

    太田博允、藤原　学、石原　健

    第30回日本分子生物学会年会・第80回日本生化学会大会  2007.12 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Molecular mechanisms regulating the sensory integration process in C.elegans.

    新海陽一、石原　健

    第30回日本分子生物学会年会・第80回日本生化学会大会  2007.12 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫の神経回路レベルで成立する嗅覚順応の分子メカニズム：Ras-MAPK経路によるグルタミン酸受容体の制御

    広津崇亮、石原　健、西田　栄介、飯野　雄一

    第30回日本分子生物学会年会・第80回日本生化学会大会  2007.12 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • 線虫C.elegansの嗅覚系におけるRas-MAPK経路の下流の探索

    平江　彰伍、広津　崇亮、飯野　雄一、石原　健

    第30回日本分子生物学会年会・第80回日本生化学会大会  2007.12 

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    Presentation type：Oral presentation (general)  

    Venue：横浜   Country：Japan  

  • Forgetting in C. elegans is accelerated by neuronal communication via the p38 MAPK pathway. International conference

    Akitoshi Inoue, Etsuko Sawatari, Takayuki Teramoto, Takeshi Ishihara

    EMBO Conference Series　C.elegans Neurobiology  2012.6 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Heidelberg   Country：Germany  

  • 4-D Ca2+ imaging of the multiple neurons that regulate the sensory integration underlying behavioral choice. International conference

    Takayuki Teramoto, Yuta Yamamoto, Takeshi Ishihara

    EMBO Conference Series　C.elegans Neurobiology  2012.6 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Heidelberg   Country：Germany  

  • snt-3 regulates memory erasing for butanone enhancement in Caenorhabditis elegans. International conference

    Etsuko Sawatari, Kenji Kaieda, Takayuki Teramoto, Takeshi Ishihara

    EMBO Conference Series　C.elegans Neurobiology  2012.6 

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    Language：English  

    Venue：Heidelberg   Country：Germany  

  • Chemotaxis behavior is regulated by germline in C. elegans International conference

    Manabi Fujiwara, Noriko Sato, Shinichi Maruyama, Takeshi Ishihara

    EMBO Conference Series　C.elegans Neurobiology  2012.6 

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    Language：English  

    Venue：Heidelberg   Country：Germany  

  • 線虫C. elegansを用いた忘却シグナルの探索

    北園智弘, 井上明俊, 石原 健

    文部科学省新学術領域研究「包括型脳科学研究推進支援ネットワーク」夏のワークショップ  2012.7 

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    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫C. elegansを用いた忘却シグナルの探索

    北園智弘, 井上明俊, 石原 健

    日本遺伝学会第84回大会  2012.9 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • 生殖細胞が制御する線虫の感覚行動 Invited

    藤原 学, 佐藤則子, 石原 健

    第３５回日本分子生物学会  2012.9 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • 線虫C. elegansにおける３次元構成画像の解析に基づく多数の神経活動の同時測定

    石原 健, 寺本 孝行

    バイオイメージ・インフォマティクス ワークショップ2012  2012.11 

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    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：神戸   Country：Japan  

  • 線虫C. elegansの神経回路における忘却の制御機構 Invited

    石原 健

    記憶回路研究会  2012.11 

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    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：岡崎   Country：Japan  

  • Acceleration of forgetting by neuronal communication in C. elegans. Invited International conference

    Takeshi Ishihara

    INTERNATIONAL SYMPOSIUM ON ORGANIZATION AND FUNCTION OF THE NERVOUS SYSTEM  2012.11 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Tokyo   Country：Japan  

  • 線虫C. elegansを用いた忘却シグナルの探索

    北園智弘, 井上明俊, 石原 健

    第３５回日本分子生物学会  2012.12 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • 線虫C. elegansにおいて記憶の忘却はTIR-1/JNK経路を介した神経間シグナル分泌により促進される

    井上明俊, 猿渡 悦子, 寺本 孝行, 石原 健

    第35回日本分子生物学会年会  2012.12 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • シナプトタグミン類似タンパク質SNT-3は線虫C. elegansにおいてブタノンエンハンスメントの記憶の消去を制御する

    猿渡 悦子, 海江田兼次, 石原 健, 寺本 孝行

    第３５回日本分子生物学会  2012.12 

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    Language：Japanese  

    Venue：福岡   Country：Japan  

  • 線虫の成長に伴う行動変化に関わるミトコンドリアの働き Invited

    藤原 学, 佐藤則子, 石原 健

    第３５回日本分子生物学会  2012.12 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • 4-D Ca2+イメージングによる線虫C. elegansの行動選択を制御する複数ニューロンの活動の可視化と計測 Invited

    寺本 孝行, 石原 健

    第３５回日本分子生物学会  2012.12 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：福岡   Country：Japan  

  • 記憶の忘却を制御するTIR-1/JNK-1経路の下流因子の探索

    北園智弘, 井上明俊, 石原 健

    第36回日本神経科学大会  2013.6 

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    Language：Japanese  

    Venue：京都   Country：Japan  

  • 4-D Ca2+ imaging of the multiple neurons in a local circuit regulating behavioral choice International conference

    Takayuki Teramoto, Yuta Yamamoto, Takeshi Ishihara

    19th International C.elegans Meeting  2013.6 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Los Angels   Country：United States  

  • Ca2+ dynamics of a whole single neuron International conference

    Takayuki Teramoto, Sayuri Kuge, Takeshi Ishihara

    19th International C.elegans Meeting  2013.6 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Los Angels   Country：United States  

  • Identification of regulatory factors for forgetting in C. elegans International conference

    Tomohiro Kitazono, Akitoshi Inoue, Takeshi Ishihara

    19th International C.elegans Meeting  2013.6 

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    Language：English   Presentation type：Oral presentation (general)  

    Venue：Los Angels   Country：United States  

  • C. elegansの中枢神経系まるごとのカルシウムイメージングに向けて Invited

    寺本 孝行, 石原 健

    包括的脳科学研究推進支援ネットワーク　平成25 年度 夏のワークショップ  2013.9 

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    Language：Japanese   Presentation type：Symposium, workshop panel (public)  

    Venue：名古屋   Country：Japan  

  • 線虫の感覚行動のライフサイクルにおける変化

    藤原 学, 佐藤則子, 丸山新一, 石原 健

    第３６回日本分子生物学会  2013.12 

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    Language：Japanese  

    Venue：神戸   Country：Japan  

  • 単一ニューロンにおけるCa2+ダイナミクス

    久下 小百合, 寺本 孝行, 石原 健

    第36回日本分子生物学会年会  2013.12 

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    Language：Japanese  

    Venue：神戸   Country：Japan  

  • 自由行動線虫の全脳神経活動計測における自動追跡システムの開発

    宍戸 耀, 冨菜 雄介, 豊島 有, 金森 真奈美, 久世 晃暢, 村上 悠子, 大江 紗, 石原 健, 飯野 雄一, 三上 秀治

    バイオイメージング  2024.9  日本バイオイメージング学会

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    Language：Japanese  

  • 深層学習による自由行動下線虫の全脳神経活動解析

    椋本 一輝, 冨菜 雄介, 豊島 有, 宍戸 耀, Wen Chentao, 金森 真奈美, 久世 晃暢, 村上 悠子, 大江 紗, 石原 健, 大浪 修一, 飯野 雄一, 三上 秀治

    バイオイメージング  2024.9  日本バイオイメージング学会

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    Language：Japanese  

▼display all

MISC

  • 忘却の分子・神経回路メカニズム

    新井美存　石原健

    BRAIN and NERVE－神経研究の進歩   2018.7

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • 神経の丸ごとの観測による神経回路の解析

    石原 健, Takayuki Teramoto, 飯野雄一

    生体の科学   2014.10

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • 線虫C.elegansにおける連合学習のメカニズム

    石原　健

    神経の分化，回路形成，機能発現　Vol.53 No.4(蛋白質 核酸 酵素2008年3月号増刊)   2008.3

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • 線虫C. elegansの行動可塑性

    石原　健

    実験医学増刊　「脳機能研究の新展開」   2006.9

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

    Behavioral plasticity in C. elegans

  • 感覚情報の統合と連合学習の制御の分子メカニズム

    石原　健

    Clinical Neuroscience Vol.23 No.4 468 2005   2005.4

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • 線虫学習行動の分子遺伝学：連合学習制御遺伝子

    石原　健

    蛋白質・核酸・酵素   2004.1

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • モデル動物を用いた記憶・学習にかかわる制御機構の解析

    石原　健

    Molecular Medicine   2004.1

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • 線虫C.elegansにおける感覚情報の統合と学習に関わる分子メカニズム

    石原　健

    生物物理   2003.1

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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Industrial property rights

Patent   Number of applications: 0   Number of registrations: 1
Utility model   Number of applications: 0   Number of registrations: 0
Design   Number of applications: 0   Number of registrations: 0
Trademark   Number of applications: 0   Number of registrations: 0

Professional Memberships

  • 日本神経科学学会

  • 日本分子生物学会

  • 日本遺伝学会

Academic Activities

  • Screening of academic papers

    Role(s)： Peer review

    2024

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：4

  • Screening of academic papers

    Role(s)： Peer review

    2023

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：4

  • Screening of academic papers

    Role(s)： Peer review

    2022

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：3

  • Screening of academic papers

    Role(s)： Peer review

    2021

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：3

  • Screening of academic papers

    Role(s)： Peer review

    2020

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：5

  • Screening of academic papers

    Role(s)： Peer review

    2019

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：5

  • Screening of academic papers

    Role(s)： Peer review

    2018

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：5

  • Screening of academic papers

    Role(s)： Peer review

    2017

    　More details

    Type：Peer review 

    Number of peer-reviewed articles in foreign language journals：5

  • International Organizing Committee International contribution

    the C. elegans Development, Cell Biology, and Gene Expression Topic Meeting in association with the 6th Asia-Pacific C. elegans Meeting  （ Nara Japan ） 2014.7

    　More details

    Type：Competition, symposium, etc. 

    Number of participants：200

  • 座長（Chairmanship） International contribution

    the C. elegans Development, Cell Biology, and Gene Expression Topic Meeting in association with the 6th Asia-Pacific C. elegans Meeting  （ Nara Japan ） 2014.7

    　More details

    Type：Competition, symposium, etc. 

  • プログラム委員

    日本生化学会大会  （ Japan ） 2012.12

    　More details

    Type：Competition, symposium, etc. 

  • 座長（Chairmanship）

    分子生物学会  （ Japan ） 2012.12

    　More details

    Type：Competition, symposium, etc. 

  • 座長（Chairmanship）

    日本分子生物学会  （ Japan ） 2012.12

    　More details

    Type：Competition, symposium, etc. 

  • プログラム委員

    日本遺伝学会第84回大会  （ Japan ） 2012.9

    　More details

    Type：Competition, symposium, etc. 

  • 座長（Chairmanship）

    日本遺伝学会  （ Japan ） 2012.9

    　More details

    Type：Competition, symposium, etc. 

  • 座長（Chairmanship）

    分子生物学会  （ Japan ） 2011.12

    　More details

    Type：Competition, symposium, etc. 

  • 座長（Chairmanship）

    日本神経科学学会  （ Japan ） 2011.9

    　More details

    Type：Competition, symposium, etc. 

  • 主催

    システム分子行動学　イメージングワークショップ  （ Japan ） 2010.8

    　More details

    Type：Competition, symposium, etc. 

    Number of participants：45

  • ヘッドオーガナイザー International contribution

    East Asia Worm Meeting  （ Korea ） 2006.11 - 2006.4

    　More details

    Type：Competition, symposium, etc. 

    Number of participants：160

  • プログラム委員

    第２８回日本分子生物学会年会  （ Japan ） 2005.12

    　More details

    Type：Competition, symposium, etc. 

    Number of participants：6,000

  • 座長（Chairmanship）

    第２８回日本分子生物学会年会  （ Japan ） 2005.12

    　More details

    Type：Competition, symposium, etc. 

  • オーガナイザー International contribution

    第２回C. elegans 日本集会  （ Japan ） 2000.8 - 2000.4

    　More details

    Type：Competition, symposium, etc. 

    Number of participants：250

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Research Projects

  • Mechanisms for forgetting in olfactory learning in C. elegans

    Grant number：19H03326  2019 - 2022

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Ishihara Takeshi

    　 More details

    Authorship：Principal investigator  Grant type：Scientific research funding

    Animals store various pieces of sensory information as memories, but they adapt to rapidly changing environments by actively forgetting some of those memories. We are studying the mechanism of active forgetting using the nematode C. elegans. In this study, we have revealed that forgetting is controlled by functionally changing the neural circuits after learning. Furthermore, we have demonstrated that memories can become unrecallable even if they exist in the nerve cells, through diacylglycerol. We have also revealed that the recall of these memories is regulated through neural circuits. These findings are crucial for unraveling the mechanisms of active forgetting in higher animals.

    CiNii Research

  • 行動の頑健性と柔軟性を制御する神経回路動態の可視化と機能制御

    Grant number：18H05135  2018 - 2019

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫C. elegansの忘却制御機構から探る記憶のダイナミズム

    Grant number：25115009  2013 - 2018

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫をモデルとした忘却を促進する神経回路の解明

    Grant number：25115724  2013 - 2015

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫中枢神経系の全ニューロンの神経活動を同時にイメージングする方法の確立

    Grant number：24650167  2012 - 2014

    Grants-in-Aid for Scientific Research  Grant-in-Aid for challenging Exploratory Research

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 記憶の忘却を制御する分子・神経回路メカニズムの遺伝学的解析

    Grant number：23370002  2011 - 2013

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Authorship：Principal investigator  Grant type：Scientific research funding

  • 包括型脳科学研究推進支援ネットワーク　行動解析融合型プラットホーム支援活動　ハイスループットモデル動物

    Grant number：221S0003  2010 - 2014

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

    　 More details

    Authorship：Coinvestigator(s)  Grant type：Scientific research funding

  • 神経回路における感覚情報処理の制御機構の解明

    Grant number：20115003  2008 - 2012

    Japan Society for the Promotion of Science・Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Innovative Areas

    　 More details

    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫Ｃ．ｅｌｅｇａｎｓをモデルとした記憶を忘れるメカニズムの分子遺伝学的解析

    Grant number：19657005  2007 - 2009

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Exploratory Research

    　 More details

    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫の神経回路における感覚情報処理制御機構

    2007 - 2008

    内藤記念科学奨励金（研究助成）

    　 More details

    Authorship：Principal investigator  Grant type：Contract research

  • 線虫の神経回路における情報処理機構−多面的なアプローチによる分子遺伝学的研究−

    Grant number：18370004  2006 - 2009

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    　 More details

    Authorship：Principal investigator  Grant type：Scientific research funding

  • 線虫C. elegansの行動を指標とした環境適応戦略の解析

    2006 - 2009

    自然科学系研究助成申請書　（財団法人旭硝子財団）

    　 More details

    Authorship：Principal investigator  Grant type：Contract research

  • 情報の統合と連合学習の素過程の制御を担う神経回路と分子機構

    Grant number：18022031  2006 - 2007

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research on Priority Areas

    　 More details

    Authorship：Principal investigator  Grant type：Scientific research funding

  • 旭硝子財団平成１８年度自然科学系研究助成 線虫C. elegansの行動を指標とした環境適応戦略の解析

    2006

    　 More details

    Grant type：Donation

  • 21COE「統合生命科学」

    2004.4 - 2007.3

    日本学術振興会（日本） 

    　 More details

    Authorship：Coinvestigator(s) 

▼display all

Class subject

  • 生物学演習I

    2024.10 - 2025.3   Second semester

  • 生物科学Ⅱ

    2024.10 - 2024.12   Fall quarter

  • 生物科学特論Ⅳ

    2024.10 - 2024.12   Fall quarter

  • 基礎生命科学

    2024.4 - 2024.9   First semester

  • 細胞生物学

    2024.4 - 2024.9   First semester

  • 生物学演習I

    2023.10 - 2024.3   Second semester

  • 生物科学Ⅱ

    2023.10 - 2023.12   Fall quarter

  • 基礎生命科学

    2023.4 - 2023.9   First semester

  • 生物物理学

    2023.4 - 2023.9   First semester

  • 細胞生物学

    2023.4 - 2023.9   First semester

  • 統合生物科学特論Ⅰ

    2023.4 - 2023.9   First semester

  • Integrative Biology, Advanced CourseⅠ

    2023.4 - 2023.9   First semester

  • 基礎生命科学

    2023.4 - 2023.9   First semester

  • 細胞生物学

    2023.4 - 2023.9   First semester

  • 生物物理学

    2023.4 - 2023.9   First semester

  • 生物学演習I

    2022.10 - 2023.3   Second semester

  • 生物科学Ⅱ

    2022.10 - 2022.12   Fall quarter

  • Basic BiologyⅡ

    2022.10 - 2022.12   Fall quarter

  • 生物科学特論Ⅳ

    2022.10 - 2022.12   Fall quarter

  • 生物科学特論Ⅳ

    2022.10 - 2022.12   Fall quarter

  • 基礎生命科学

    2022.4 - 2022.9   First semester

  • 細胞生物学

    2022.4 - 2022.9   First semester

  • 生物学演習I

    2021.10 - 2022.3   Second semester

  • 生物科学Ⅱ

    2021.10 - 2021.12   Fall quarter

  • Basic BiologyⅡ

    2021.10 - 2021.12   Fall quarter

  • 統合生物科学特論Ⅰ（※生命理学特論Ⅴ）

    2021.4 - 2021.9   First semester

  • 基礎生命科学

    2021.4 - 2021.9   First semester

  • 生物物理学

    2021.4 - 2021.9   First semester

  • 細胞生物学

    2021.4 - 2021.9   First semester

  • 統合生物科学特論Ⅰ

    2021.4 - 2021.9   First semester

  • Integrative Biology, Advanced CourseⅠ

    2021.4 - 2021.9   First semester

  • 統合生物科学特論Ⅰ（※生命理学特論Ⅳ）

    2021.4 - 2021.9   First semester

  • 生物学演習I

    2020.10 - 2021.3   Second semester

  • Molecular Life Sciences, Advanced Course Ⅳ

    2020.10 - 2020.12   Fall quarter

  • 分子生命科学基礎II

    2020.10 - 2020.12   Fall quarter

  • 分子生命科学特論Ⅳ

    2020.10 - 2020.12   Fall quarter

  • 細胞生物学

    2020.4 - 2020.9   First semester

  • 基礎生命科学

    2020.4 - 2020.9   First semester

  • 生物物理学

    2020.4 - 2020.9   First semester

  • 分子遺伝学

    2020.4 - 2020.9   First semester

  • 生物物理学

    2019.10 - 2020.3   Second semester

  • 生物学演習I

    2019.10 - 2020.3   Second semester

  • 遺伝学

    2019.4 - 2019.9   First semester

  • 基礎生命科学

    2019.4 - 2019.9   First semester

  • 分子遺伝学

    2019.4 - 2019.9   First semester

  • 細胞生物学

    2019.4 - 2019.9   First semester

  • 生物学演習I

    2018.10 - 2019.3   Second semester

  • 分子生命科学特論Ⅳ

    2018.10 - 2018.12   Fall quarter

  • Basic Molecular Life Sciences Ⅱ

    2018.10 - 2018.12   Fall quarter

  • 分子遺伝学

    2018.4 - 2018.9   First semester

  • 基礎生命科学

    2018.4 - 2018.9   First semester

  • 遺伝学

    2018.4 - 2018.9   First semester

  • 生化学Ⅰ

    2018.4 - 2018.9   First semester

  • 生物学特別講義Ⅳ

    2018.4 - 2018.9   First semester

  • 細胞生物学

    2018.4 - 2018.9   First semester

  • 生物学演習I

    2017.10 - 2018.3   Second semester

  • 分子生命科学特別講義

    2017.10 - 2018.3   Second semester

  • 分子生命科学特別講義

    2017.10 - 2018.3   Second semester

  • 生物学演習I

    2017.10 - 2018.3   Second semester

  • 分子生物学II

    2017.10 - 2017.12   Fall quarter

  • 分子生命科学Ⅱ

    2017.10 - 2017.12   Fall quarter

  • Basic Molecular Life Sciences Ⅱ

    2017.10 - 2017.12   Fall quarter

  • 分子遺伝学講究

    2017.4 - 2018.3   Full year

  • 分子遺伝学講究

    2017.4 - 2018.3   Full year

  • 分子生命科学特別演習I

    2017.4 - 2018.3   Full year

  • 分子生命科学特別演習II

    2017.4 - 2018.3   Full year

  • 分子遺伝学

    2017.4 - 2017.9   First semester

  • 基礎生命科学

    2017.4 - 2017.9   First semester

  • 遺伝学

    2017.4 - 2017.9   First semester

  • 生化学Ⅰ

    2017.4 - 2017.9   First semester

  • 細胞生物学

    2017.4 - 2017.9   First semester

  • 基礎生命科学

    2017.4 - 2017.9   First semester

  • 分子遺伝学

    2017.4 - 2017.9   First semester

  • 生物学演習I

    2016.10 - 2017.3   Second semester

  • 分子生命科学特別演習I

    2016.4 - 2017.3   Full year

  • 分子遺伝学講究

    2016.4 - 2017.3   Full year

  • 分子生命科学特別演習II

    2016.4 - 2017.3   Full year

  • 細胞生物学

    2016.4 - 2016.9   First semester

  • 分子生物学特論

    2016.4 - 2016.9   First semester

  • 分子遺伝学

    2016.4 - 2016.9   First semester

  • 基礎生命科学

    2016.4 - 2016.9   First semester

  • 分子生物学特論

    2015.10 - 2016.3   Second semester

  • 生物学演習I

    2015.10 - 2016.3   Second semester

  • 分子生命科学特別演習I

    2015.4 - 2016.3   Full year

  • 分子遺伝学講究

    2015.4 - 2016.3   Full year

  • 分子生命科学特別演習II

    2015.4 - 2016.3   Full year

  • 基礎生命科学

    2015.4 - 2015.9   First semester

  • 細胞生物学

    2015.4 - 2015.9   First semester

  • 分子遺伝学

    2015.4 - 2015.9   First semester

  • 分子細胞生物Ｉ

    2014.10 - 2015.3   Second semester

  • 分子生物学特論

    2014.10 - 2015.3   Second semester

  • 生物学演習I

    2014.10 - 2015.3   Second semester

  • 分子生命科学特別演習I

    2014.4 - 2015.3   Full year

  • 分子遺伝学講究

    2014.4 - 2015.3   Full year

  • 分子生命科学特別演習II

    2014.4 - 2015.3   Full year

  • 基礎生命科学

    2014.4 - 2014.9   First semester

  • 分子遺伝学

    2014.4 - 2014.9   First semester

  • 分子生物学特論

    2013.10 - 2014.3   Second semester

  • 生物学演習I

    2013.10 - 2014.3   Second semester

  • 分子細胞生物Ｉ

    2013.10 - 2014.3   Second semester

  • 分子生命科学特別演習I

    2013.4 - 2014.3   Full year

  • 分子遺伝学講究

    2013.4 - 2014.3   Full year

  • 分子生命科学特別演習II

    2013.4 - 2014.3   Full year

  • 分子生物学

    2013.4 - 2013.9   First semester

  • 分子遺伝学

    2013.4 - 2013.9   First semester

  • 遺伝学

    2013.4 - 2013.9   First semester

  • 分子細胞生物Ｉ

    2012.10 - 2013.3   Second semester

  • 分子生物学特論

    2012.10 - 2013.3   Second semester

  • 生物学演習I

    2012.10 - 2013.3   Second semester

  • 分子生命科学特別演習I

    2012.4 - 2013.3   Full year

  • 分子遺伝学講究

    2012.4 - 2013.3   Full year

  • 分子生命科学特別演習II

    2012.4 - 2013.3   Full year

  • 分子生物学

    2012.4 - 2012.9   First semester

  • 分子生物学基礎

    2012.4 - 2012.9   First semester

  • 分子遺伝学

    2012.4 - 2012.9   First semester

  • 遺伝学

    2012.4 - 2012.9   First semester

  • 分子細胞生物Ｉ

    2011.10 - 2012.3   Second semester

  • 分子遺伝学特論

    2011.10 - 2012.3   Second semester

  • 生物学演習III

    2011.10 - 2012.3   Second semester

  • 生物学演習I

    2011.10 - 2012.3   Second semester

  • 生物学特別研究II

    2011.10 - 2012.3   Second semester

  • 分子生命科学特別演習II

    2011.4 - 2012.3   Full year

  • 分子生命科学特別演習I

    2011.4 - 2012.3   Full year

  • 分子遺伝学講究

    2011.4 - 2012.3   Full year

  • 分子生物学

    2011.4 - 2011.9   First semester

  • 生物学コアセミナーB

    2011.4 - 2011.9   First semester

  • 生物学演習II

    2011.4 - 2011.9   First semester

  • 分子遺伝学

    2011.4 - 2011.9   First semester

  • 生物学特別研究I

    2011.4 - 2011.9   First semester

  • 遺伝学

    2011.4 - 2011.9   First semester

  • 生物学演習III

    2010.10 - 2011.3   Second semester

  • 分子細胞生物Ｉ

    2010.10 - 2011.3   Second semester

  • 生物学特別研究II

    2010.10 - 2011.3   Second semester

  • 生物学演習I

    2010.10 - 2011.3   Second semester

  • 分子生命科学特別演習I

    2010.4 - 2011.3   Full year

  • 分子生命科学特別演習II

    2010.4 - 2011.3   Full year

  • 分子遺伝学講究

    2010.4 - 2011.3   Full year

  • 生物学演習II

    2010.4 - 2010.9   First semester

  • 分子生物学基礎

    2010.4 - 2010.9   First semester

  • 分子生物学

    2010.4 - 2010.9   First semester

  • 遺伝学

    2010.4 - 2010.9   First semester

  • 生物学特別研究I

    2010.4 - 2010.9   First semester

  • 分子遺伝学

    2010.4 - 2010.9   First semester

  • 生物学コアセミナーB

    2010.4 - 2010.9   First semester

  • 分子遺伝学特論

    2009.10 - 2010.3   Second semester

  • 生物学特別研究II

    2009.10 - 2010.3   Second semester

  • 生物学演習I

    2009.10 - 2010.3   Second semester

  • 生物学演習III

    2009.10 - 2010.3   Second semester

  • 遺伝学

    2009.4 - 2009.9   First semester

  • 生物学演習II

    2009.4 - 2009.9   First semester

  • 生物学特別研究I

    2009.4 - 2009.9   First semester

  • 生物学コアセミナーB

    2009.4 - 2009.9   First semester

  • 分子遺伝学

    2009.4 - 2009.9   First semester

  • 分子生物学

    2009.4 - 2009.9   First semester

  • 生物学特別研究II

    2008.10 - 2009.3   Second semester

  • 生物学通論

    2008.10 - 2009.3   Second semester

  • 生物学演習III

    2008.10 - 2009.3   Second semester

  • 生物科学特別研究

    2008.4 - 2009.3   Full year

  • 生物科学特別演習

    2008.4 - 2009.3   Full year

  • 生物学特別研究I

    2008.4 - 2008.9   First semester

  • 分子生物学基礎

    2008.4 - 2008.9   First semester

  • 分子生物学

    2008.4 - 2008.9   First semester

  • 分子遺伝学II

    2008.4 - 2008.9   First semester

  • 生物学コアセミナーB

    2008.4 - 2008.9   First semester

  • 遺伝学

    2008.4 - 2008.9   First semester

  • 生物学演習II

    2008.4 - 2008.9   First semester

  • 生物学演習I

    2007.10 - 2008.3   Second semester

  • 生物学演習I

    2007.10 - 2008.3   Second semester

  • 生物学特別研究II

    2007.10 - 2008.3   Second semester

  • 生物学演習III

    2007.10 - 2008.3   Second semester

  • 生物科学特別演習

    2007.4 - 2008.3   Full year

  • 生物科学特別研究

    2007.4 - 2008.3   Full year

  • 分子生物学

    2007.4 - 2007.9   First semester

  • 分子遺伝学特論

    2007.4 - 2007.9   First semester

  • 生物学特別研究I

    2007.4 - 2007.9   First semester

  • 生物学演習II

    2007.4 - 2007.9   First semester

  • 生物学特別研究I

    2007.4 - 2007.9   First semester

  • 遺伝学

    2007.4 - 2007.9   First semester

  • 生物学コアセミナーB

    2007.4 - 2007.9   First semester

  • 分子遺伝学II

    2007.4 - 2007.9   First semester

  • 生物学演習III

    2006.10 - 2007.3   Second semester

  • 分子遺伝学I

    2006.10 - 2007.3   Second semester

  • 生物学演習I

    2006.10 - 2007.3   Second semester

  • 生物学特別研究II

    2006.10 - 2007.3   Second semester

  • 生物学演習III

    2006.10 - 2007.3   Second semester

  • 分子遺伝学 I

    2006.10 - 2007.3   Second semester

  • 生物学演習I

    2006.10 - 2007.3   Second semester

  • 生物学特別研究II

    2006.10 - 2007.3   Second semester

  • 生物科学特別演習

    2006.4 - 2007.3   Full year

  • 生物科学特別研究

    2006.4 - 2007.3   Full year

  • 生物科学特別演習

    2006.4 - 2007.3   Full year

  • 生物科学特別研究

    2006.4 - 2007.3   Full year

  • 生物学演習II

    2006.4 - 2006.9   First semester

  • 分子遺伝学II

    2006.4 - 2006.9   First semester

  • 生物学コアセミナーB

    2006.4 - 2006.9   First semester

  • 生物学特別研究I

    2006.4 - 2006.9   First semester

  • 生物学演習II

    2006.4 - 2006.9   First semester

  • 現代生物学へのいざない

    2006.4 - 2006.9   First semester

  • 分子遺伝学 II

    2006.4 - 2006.9   First semester

  • 生物学コアセミナーB

    2006.4 - 2006.9   First semester

  • 生物学特別研究 I

    2006.4 - 2006.9   First semester

  • 生物学通論

    2005.10 - 2006.3   Second semester

  • 分子遺伝学　I

    2005.10 - 2006.3   Second semester

  • 生物学演習　I

    2005.10 - 2006.3   Second semester

  • 生物学特別研究　II

    2005.10 - 2006.3   Second semester

  • 生物学演習 III

    2005.10 - 2006.3   Second semester

  • 地球と生命

    2005.10 - 2006.3   Second semester

  • 生物科学特別演習

    2005.4 - 2006.3   Full year

  • 生物科学特別研究

    2005.4 - 2006.3   Full year

  • 分子遺伝学特論

    2005.4 - 2005.9   First semester

  • 分子遺伝学 II

    2005.4 - 2005.9   First semester

  • 生物学特別研究　I

    2005.4 - 2005.9   First semester

  • 生物学演習　 II

    2005.4 - 2005.9   First semester

  • 生物学演習 III

    2004.10 - 2005.3   Second semester

  • 分子遺伝学I

    2004.10 - 2005.3   Second semester

  • 生物学演習I

    2004.10 - 2005.3   Second semester

  • 生物学特別研究II

    2004.10 - 2005.3   Second semester

  • 生物科学特別研究

    2004.4 - 2005.3   Full year

  • 生物学演習 II

    2004.4 - 2004.9   First semester

  • 分子遺伝学 II

    2004.4 - 2004.9   First semester

  • 生物学特別研究 I

    2004.4 - 2004.9   First semester

  • 生物学特別演習

    2004.4 - 2004  

  • 生物科学Ⅱ

    2025.10 - 2025.12   Fall quarter

  • Basic BiologyⅡ

    2025.10 - 2025.12   Fall quarter

  • 細胞生物学

    2025.4 - 2025.9   First semester

  • 基礎生命科学

    2025.4 - 2025.9   First semester

  • 生物科学Ⅱ

    2024.10 - 2024.12   Fall quarter

  • Basic BiologyⅡ

    2024.10 - 2024.12   Fall quarter

  • 学際開拓創成セミナーⅠ

    2024.4 - 2025.3   Full year

  • 修士論文

    2024.4 - 2025.3   Full year

  • 中間考査

    2024.4 - 2025.3   Full year

  • システム生命科学特別研究

    2024.4 - 2025.3   Full year

  • システム生命科学特別演習Ⅱ

    2024.4 - 2025.3   Full year

  • システム生命科学特別演習Ⅰ

    2024.4 - 2025.3   Full year

  • 細胞生物学

    2024.4 - 2024.9   First semester

  • 生物科学特別講義Ⅴ

    2024.4 - 2024.9   First semester

  • 生物物理学

    2024.4 - 2024.9   First semester

  • 基礎生命科学

    2024.4 - 2024.9   First semester

  • Special Lecture of BiologyⅤ

    2024.4 - 2024.9   First semester

▼display all

FD Participation

  • 2024.7   Role：Speech   Title：大学教職員職能開発FD「⽣成AIを大学の教育・学習・業務にどのように組み込むか？-第四弾　教育現場における生成AIの導入事例-隣の教室の授業法-」

  • 2024.3   Role：Participation   Title：有体物管理センターの業務および成果有体物収入の配分率の変更について

    Organizer：University-wide

  • 2024.3   Role：Participation   Title：有体物管理センターの業務および成果有体物収入の配分率の変更について

    Organizer：University-wide

  • 2023.3   Role：Participation   Title：【生物学科】大学発明の出願・権利化に関するFD

    Organizer：Undergraduate school department

  • 2022.3   Role：Participation   Title：【生物学科】入学者選抜試験に関するFD

    Organizer：Undergraduate school department

  • 2021.9   Role：Participation   Title：JST 次世代研究者挑戦的研究プログラム 説明会

    Organizer：University-wide

  • 2021.7   Role：Participation   Title：COILとは？九大農学部＆共創学部の実施例

  • 2021.3   Role：Speech   Title：FD講演会「九州大学オンライン授業のグッドプラクティス 〜 リアルタイム型授業編〜」

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2021.3   Role：Speech   Title：FD講演会「九州大学オンライン授業のグッドプラクティス 〜 リアルタイム型授業編〜」

    Organizer：University-wide

  • 2020.12   Role：Participation   Title：【オンライン配信】新型コロナウィルス感染拡大状況での学生のメンタルヘルス

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2020.12   Role：Participation   Title：新型コロナウィルス感染拡大状況での学生のメンタルヘルス

    Organizer：University-wide

  • 2020.11   Role：Participation   Title：事件等発生時の学生対応に関するＦＤ・ＳＤ

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2019.10   Role：Participation   Title：（生物学科FD）科研費改革後の学術研究動向について

    Organizer：Undergraduate school department

  • 2019.9   Role：Participation   Title：M2B学習支援システム講習会☆入門編☆(伊都地区)09:30～11:30

    Organizer：University-wide

  • 2019.7   Role：Participation   Title：３ポリシーに関する全学FD　～日本学術会議分野別参照基準に基づく理学部物理学科の３ポリシー～

    Organizer：University-wide

  • 2018.6   Role：Participation   Title：平成３３年度入学者選抜改革 【九州大学新入試ＱＵＢＥ】

    Organizer：University-wide

  • 2018.5   Role：Moderator   Title：生物学科教育支援室の５年間とこれから

    Organizer：Undergraduate school department

  • 2017.9   Role：Participation   Title：学生に起こりやすい問題とその対応について

    Organizer：Undergraduate school department

  • 2016.8   Role：Participation   Title：高大連携・大学からのアプローチ

    Organizer：Undergraduate school department

  • 2013.3   Role：Participation   Title：「アクティブ・ラーニング：入門と実践」

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2012.3   Role：Participation   Title：心の危機の予防と連携－われわれ教職員にできること

    Organizer：University-wide

  • 2011.12   Role：Participation   Title：システム生命科学府のグローバル化について

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2011.6   Role：Participation   Title：教育の質向上支援プログラム成果発表会

    Organizer：University-wide

  • 2011.3   Role：Participation   Title：卒業研究やカリキュラムのあり方

    Organizer：Undergraduate school department

  • 2011.1   Role：Participation   Title：授業資料の著作権とその対策ー特にWEB配信資料について

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2010.12   Role：Participation   Title：理学研究院男女共同参画推進FD

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2010.9   Role：Participation   Title：学生の自殺予防とメンタルヘルス対応

    Organizer：University-wide

  • 2010.3   Role：Participation   Title：こころが不調になった学生の理解と接し方

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2010.1   Role：Participation   Title：学習成果達成のための教育プログラム開発

    Organizer：University-wide

  • 2009.9   Role：Participation   Title：体験活動を通じた学習成果の達成について

    Organizer：University-wide

  • 2009.7   Role：Participation   Title：自己点検・評価/外部評価の結果とカリキュラム改革

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2008.3   Role：Participation   Title：生物科学部門ファカルティディベロップメント

    Organizer：Undergraduate school department

  • 2007.10   Role：Participation   Title：生物学科コース設置による学部教育の改善

    Organizer：Undergraduate school department

  • 2005.9   Role：Participation   Title：不明

    Organizer：University-wide

  • 2005.3   Role：Participation   Title：不明

    Organizer：[Undergraduate school/graduate school/graduate faculty]

  • 2004.12   Role：Participation   Title：不明

    Organizer：University-wide

▼display all

Visiting, concurrent, or part-time lecturers at other universities, institutions, etc.

  • 2014  東京工業大学生命理工学部  Classification:Part-time lecturer  Domestic/International Classification:Japan 

    Semester, Day Time or Duration：１

  • 2002  神戸大学大学院・医学研究院  Classification:Intensive course  Domestic/International Classification:Japan 

    Semester, Day Time or Duration：後期・集中講義

Social Activities

  • 九州大学生物学科オンライン研究室紹介(2回）

    夢ナビ2023（福岡）  2023.7

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Other

  • 研究紹介

    伝習館高校  2023.2

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Other

  • 九州大学生物学科オンライン研究室紹介

    夢ナビ2020（福岡）  2020.9

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Other

  • 遺伝子からみた情報処理

    夢ナビ2020（福岡）  2020.9

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 遺伝子からみた情報処理

    大分市ホルトホール  2019.2

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 遺伝子からみた情報処理

    春日高校  2014.11

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 研究紹介

    久留米大学付設中学校  2011.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Other

  • 遺伝子からみた情報処理

    宮崎北高校  2011.6

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • リカレント教育

    2010.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 教員免許状更新講習

    2010.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • Qcafe 2009 脳シリーズ 第２話講師

    平成21年度P&Pアウトリーチ：脳を語ろう  西鉄イン　コマンタレブー  2010.1

    　More details

    Audience：General,　Scientific,　Company,　Civic organization,　Governmental agency

    Type：Lecture

  • 教員免許状更新講習

    2009.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 福岡県　２１世紀人材育成推進事業 知の最前線探訪

    福岡県高等教育機構  2007.12

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 福岡県教育委員会 スーパーサイエンスセミナー

    福岡県教育委員会  2007.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 福岡県　２１世紀人材育成推進事業 ハイレベル合宿

    福岡県高等教育機構  2007.8

    　More details

    Audience：Infants,　Schoolchildren,　Junior students,　High school students

    Type：Seminar, workshop

  • 遺伝子からみた情報処理-単純な神経系を持つ線虫をモデルとして

    九州大学大学院理学研究院・生物科学部門  九州大学六本松地区　五号館５１０番  2005.8

    　More details

    Audience：General,　Scientific,　Company,　Civic organization,　Governmental agency

    Type：Lecture

▼display all

Media Coverage

  • 記憶を思い出させるシグナル経路を発⾒ 記憶を“思い出せないこと”と“忘れていること”の違い というタイトルで、私達の研究が紹介された。 Newspaper, magazine

    esse-sense  2022.11

    　More details

    記憶を思い出させるシグナル経路を発⾒
    記憶を“思い出せないこと”と“忘れていること”の違い
    というタイトルで、私達の研究が紹介された。

  • 卓上四季にて紹介される Newspaper, magazine

    北海道新聞  2013.4

    　More details

    卓上四季にて紹介される

  • 積極的に記憶の消去促す神経細胞と制御機構発見」 Newspaper, magazine

    科学新聞  2013.4

    　More details

    積極的に記憶の消去促す神経細胞と制御機構発見」

  • 「記憶の忘却促す細胞を発見」 Newspaper, magazine

    東京新聞  2013.3

    　More details

    「記憶の忘却促す細胞を発見」

  • 「記憶を忘れさせる細胞」 Newspaper, magazine

    西日本新聞  2013.3

    　More details

    「記憶を忘れさせる細胞」

  • 「忘却の仕組み解明へ」 Newspaper, magazine

    毎日新聞  2013.3

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Activities contributing to policy formation, academic promotion, etc.

  • 2016.3 - Present   基礎生物学研究所

    IBBP(大学連携バイオバックアッププロジェクト）運営委員及び九州サテライト代表者