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Hiroyuki Tashiro Last modified date:2023.11.22

Lecturer / Division of Medical Technology
Department of Health Sciences
Faculty of Medical Sciences


Graduate School
Undergraduate School


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Homepage
https://kyushu-u.elsevierpure.com/en/persons/hiroyuki-tashiro
 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Ph.D.
Country of degree conferring institution (Overseas)
Yes Doctor
Field of Specialization
Medical Engineering
ORCID(Open Researcher and Contributor ID)
0000-0001-5669-154X
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
[Research activity]
We develope an artificial vision system for a human body.
The objective of this R&D is to assist the blind and people with seriously damaged eyes because of damaged retina functions to recover visual functions by replacing damaged areas with an artificial system.

[Education activity]
I teach compendium of medical engineering.

[Social activity]
I assist research and development at the manufacturer of medical devices as a consulting engineer.
Research
Research Interests
  • Development of Artificial Vision System
    keyword : Aritificial Vision System, Artificial Retina, Visual Prosthesis, Artificail Organ
    2001.09The objective of R&D of artificial vision system is to assist the blind and people with seriously damaged eyes because of damaged retina functions to recover visual functions by replacing damaged areas with an artificial system. More specifically, an artificial system capable of simulating the visual function by allowing the signals of an imaging device implanted inside of the eye or outside of the body to directly transmit an electric stimulus to retina cells through an electrode capable of stimulating the retina will be developed..
  • Development of medical equipment applying neuromodulation
    keyword : Neuromodulation, tDCS, rTMS, MicroCurrent Stimulation
    2016.04.
  • Optimization of environmental lighting in ultrasonography
    keyword : ultrasonography, environmental lighting, comfort, fatigue
    2006.01~2012.03.
Current and Past Project
  • In Japan, there are more than 300,000 visually impaired people, of which 170,000 are said to be blind. There is no effective treatment and it is considered impossible to recover their sight. We develope an artificial sight system based on the Suprachoroidal Transretinal Stimulation (or STS) method which replaces the impaired visual function with artificial devices, and evaluate biocompatibility and durability of the device.
  • The objective of R&D of artificial vision system is to assist the blind and people with seriously damaged eyes because of damaged retina functions to recover visual functions by replacing damaged areas with an artificial system. More specifically, an artificial system capable of simulating the visual function by allowing the signals of an imaging device implanted inside of the eye or outside of the body to directly transmit an electric stimulus to retina cells through an electrode capable of stimulating the retina will be developed.
Academic Activities
Books
1. Marko B. Popovic, Kathleen A. Lamkin-Kannard, Hiroyuki Tashiro, Philipp Beckerle, Steffen Willwacher, Minas Liarokapis, Michelle J. Johnson, Adam D. Goodworth, Pinar Boyraz, Ivo Dobrev, Biomechatronics, Academic Press, Elsevier, 10.1016/C2016-0-04132-3, Chapter 19, Practice Problems, pp. 567-604, 2019.04, [URL].
2. Hiroyuki Tashiro, Marko B. Popovic, Ivo Dobrev, Yasuo Terasawa, Biomechatronics, Academic Press, Elsevier, 10.1016/C2016-0-04132-3, Chapter 7, Artificial Organs, Tissues, and Support Systems, pp. 175-199, 2019.04, [URL].
3. Hiroyuki Tashiro, Marko B. Popovic, Keiji Iramina, Yasuo Terasawa, Jun Ohta, Biomechatronics, Academic Press, Elsevier, 10.1016/C2016-0-04132-3, Chapter 6, Direct Neural Interface, pp. 139-174, 2019.04, [URL].
4. Takashi Tokuda, Jun Ohta, Hiroyuki Tashiro, Yasuo Terasawa, John G. Webster (ed.), Wiley Encyclopedia of Electrical and Electronics Engineering, John Wiley & Sons, 10.1002/047134608x.w8370, Retinal Prosthesis, 17 pages, 2018.05, [URL], Retinal prosthesis technologies have been intensively studied over the past decades and some projects are in the clinical trial or conditional commercialization phase. Electronic components play essential roles in the retinal prosthesis technologies. In this article, we present basic aspects and the status of the retinal prosthesis field from an electronics-oriented viewpoint. Important concepts, stimulation schemes, device designs, and other essential elements related to retinal prosthesis are discussed. Some leading projects in the field are also mentioned together with reference information..
5. HANDBOOK OF PRACTICAL IMAGE ANALYSIS IN MEDICINE, Chapter 4 Biomedical Optics, 4.6.2Funduscopy.
Reports
1. Monitor adjustment on ultrasonography, [URL].
2. Aim for the Achievment of Visual Prosthetis.
Papers
1. Yasuo Terasawa, Hiroyuki Tashiro, Tokio Ueno, Jun Ohta, Precise Temporal Control of Interferential Neural Stimulation via Phase Modulation, IEEE Transactions on Biomedical Engineering, 10.1109/TBME.2021.3091689, 69, 1, 220-228, 2022.01, [URL], Objective: Noninvasive neural stimulation via temporally interferential (TI) electrical field is currently an area of interest as a noninvasive method of brain stimulation. The major limitation of TI stimulation is the difficulty of precise temporal control of the stimulation, due to the nature of the sinusoidal envelope generated by the interference. The purpose of this study was to investigate the possibility of improving interferential stimulation by introducing precise temporal control using phase modulation. Methods: In conventional TI, a sinusoidal current is applied to two electrode pairs with slightly different frequencies, to cause interference. In this paper we describe phase modulation interference (PMI). Instead of shifting frequency, the phase of a sinusoidal wave was partially modulated, causing a transient increase or decrease of the envelope. The spatial distribution of envelope modulation amplitude by TI and PMI was visualized using both electromagnetic simulation and actual measurement using tissue phantom. Results: The measured voltage transient in the tissue phantom produce a precise, temporally controlled pulse-like envelope using PMI. The spatial distributions of the amplitude of the envelope modulation by TI and PMI did not differ significantly, and were consistent with electromagnetic simulation. Conclusion: PMI allows precise temporal control of interferential stimulation, thus increasing the practical utility of interferential stimulation. Significance: PMI improves interferential stimulation, allowing more temporally precise stimulation to neural tissue located distantly from the stimulating electrodes..
2. Shuhei Nomura, Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Makito Haruta, Kiyotaka Sasagawa, Hironari Takehara, Jun Ohta, Randles Circuit Model for Characterizing a Porous Stimulating Electrode of the Retinal Prosthesis, IEEJ Transactions on Sensors and Micromachines, Vol. 141, Issue 5, pp. 134-140 (2021). , [URL].
3. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Jun Ohta, Porosification of Surface of Platinum Electrode by Anisotropic Etching, Sensors and Materials, 10.18494/SAM.2019.2334, 6, 2, 1957-1971, 2019.06, [URL].
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6. Yurina Yoshimura, Haruna Doi, Yasuo Terasawa, Hiroyuki Tashiro, Study on purity required for preparation process of photoswitch molecule (BENAQ) by cytotoxicity test of Nitroazobenzene S1, IEICE Technical Report, vol. 117, no. 416, MBE2017-77, pp. 59-64 (2018)., [URL].
7. Mariko Kuwabara, Hiroyuki Tashiro, Yukari Nakano, Yasuo Terasawa, Hajime Sawai, Jun Ohta, Comparative Study of Sevoflurane and Isoflurane Anesthesia for the Long-term Safety Evaluation of Visual Prosthesis with Rabbits, Sensors and Materials, 10.18494/SAM.2018.1715, 30, 2, 287-297, S&M1491, 2018.01, [URL].
8. Hiroyuki Tashiro, Mariko Kuwabara, Yukari Nakano, Yasuo Terasawa, Koji Osawa, Yurina Yoshimura, Haruna Doi, Jun Ohta, In Vitro and In Vivo Long-term Electrochemical Properties of Electrodes with Femtosecond-laser-induced Porosity for Visual Prostheses Based on Suprachoroidal Transretinal Stimulation, Sensors and Materials, 10.18494/SAM.2018.1723, 30, 2, 251-268, S&M1489, 2018.01, [URL].
9. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Jun Ohta, Safety and Efficacy of Semichronic Suprachoroidal Transretinal Stimulation with Femtosecond Laser-induced Porosity and Smooth-surface Electrodes, Sensors and Materials, 10.18494/SAM.2018.1652, 30, 2, 235-249, S&M1488, 2018.01, [URL].
10. Mariko Kuwabara, Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Yurina Yoshimura, Koji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Long-Term Analysis of In Vivo Characteristics of Recording Electrode Using Electrochemical Impedance Spectroscopy, Sensors and Materials, http://dx.doi.org/10.18494/SAM.2017.1635, 29, 12, 1689-1702, 2017.12, [URL].
11. Mariko Kuwabara, Hiroyuki Tashiro, Yasuo Terasawa, Koji Osawa, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Development of Chronic Implantable Electrodes for Long-term Visual Evoked Potential Recording in Rabbits, Advanced Biomedical Engineering, 10.14326/abe.6.59, 6, 59-67, 2017.05, [URL].
12. Hiroyuki Tashiro, Yasuo Terasawa, Kuwabara Mariko, Koji Osawa, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Initial Evaluation of the Safety and Durability of Retinal Prostheses Based on Suprachoroidal– transretinal Stimulation using Bullet-shaped Platinum Electrodes, Advanced Biomedical Engineering, http://doi.org/10.14326/abe.6.8, 6, 8-14, 2017.02, [URL].
13. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Takashi Tokuda, Jun Ohta, Mechanical Machining-based Three-Dimensional Electrode Array for Chronic Neural Stimulation, Advanced Biomedical Engineering, 10.14326/abe.5.137, 5, 137-141, Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Takashi Tokuda, Jun Ohta, Mechanical Machining-based Three-Dimensional Electrode Array for Chronic Neural Stimulation, Advanced Biomedical Engineering, Vol. 5, pp. 137-141 (2016)., 2016.12, [URL].
14. Hiroyuki Tashiro, Yasuo Terasawa, Kazutoshi Haraguchi, Koji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Feasibility Study of High-Performance Implantable Stimulation Electrode with Nanocomposite Gel Coating as a Brain-Machine Interface Device, Sensors and Materials, 10.18494/SAM.2016.1290, 28, 12, 1283-1293, 2016.12, [URL].
15. , [URL].
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17. Yasuo Terasawa, Hiroyuki Tashiro, Akihiro Uehara, Tohru Saitoh, Motoki Ozawa, Takashi Tokuda, Jun Ohta, The development of a multichannel electrode array for retinal prostheses, Jounal of Artificial Organs, 10.1007/s10047-006-0352-1, 9, 263-266, 2006.09.
Presentations
1. Kenji Sugie, Kiyotaka Sasagawa, Hironari Takehara, Makito Haruta, Hiroyuki Tashiro, Jun Ohta, Implantable CMOS Image Sensor with Neural Amplifier for Imaging and Electrophysiological Recording, 10th International IEEE EMBS Conference on Neural Engineering (NER'21), 2021.05.
2. Kyosuke Naganuma, Yasumi Ohta, Yoshinori Sunaga, Hironari Takehara, Makito Haruta, Hiroyuki Tashiro, Kiyotaka Sasagawa, Yasemin M. Akay, Metin Akay, Jun Ohta, Nano-Pt Coating on Electrode Surface of a Multifunctional Neural Probe with a CMOS Image Sensor, 10th International IEEE EMBS Conference on Neural Engineering (NER'21), 2021.05.
3. Yasuo Terasawa, Hiroyuki Tashiro, Jun Ohta, Visualizing Electric Field patterns generated by Temporal Interference Stimulation of Retina: Measurements using a phantom eye, The Association for Research in Vision & Ophthalmology (ARVO) 2021 Annual Meeting, 2021.05, [URL].
4. Yasuo Terasawa, Hiroyuki Tashiro, Jun Ohta, Atsushi Tanaka, Spatiotemporal Aspects of Suprachoroial Retinal Stimulation using Temporally Interfering Electric Fields, 2020 The Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, 2020.05, [URL].
5. Yasuo Terasawa, Hiroyuki Tashiro, Jun Ohta, Suprachoroial retinal stimulation using temporally interfering electric fields: A simulation study, Artificial Vision 2019, 2019.12, [URL].
6. Hiroyuki Tashiro, A review of optical neural stimulation: considering applications to artificial retina, 2019 NAIST NCTU Joint Workshop on Biomedical Devices and Materials, 2019.12.
7. Shuhei Nomura, Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Jun Ohta, Electrochemical Characterization of Implantable Porous Electrode During Long-Term In Vivo Stimulation Using Electrochemical Impedance Spectroscopy, International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications (Bio4Apps 2018/2019), 2019.01, [URL].
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10. Yurina Yoshimura, Haruna Doi, Yasuo Terasawa, Hiroyuki Tashiro, Study on purity required for preparation process of photoswitch molecule (BENAQ) by cytotoxicity test of Nitroazobenzene S1, IEICE Technical Committee on ME and Bio Cybernetics (MBE), IEICE-MBE2017-77, Kyushu Institute of Technology, Japan, 2018. 1.27., [URL].
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14. Mariko Kuwabara, Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Analysis of the Porous Stimulation Electrode Characteristic Using Electrochemical Impedance Spectroscopy in Visual Prostheses, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2017), 2017.07, [URL].
15. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Motoki Ozawa, Stability of the suprachoroidal electrode array during one-month implantation in rabbit eyes, The Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) 2017, 2017.05, [URL].
16. Kuwabara Mariko, Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Yurina Yoshimura, Kouji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Long-term Analysis of the In Vivo Characteristics of a Recording Electrode with Electrochemical Impedance Spectroscopy, International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications (Bio4Apps 2016), 2016.12, [URL].
17. Hiroyuki Tashiro, Yasuo Terasawa, Kazutoshi Haraguchi, Koji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Possibility and limitation of electrode performance improvement by hydrogel coating for neural stimulation, JST 2016 Taiwan-Japan Joint Symposium, 2016.10.
18. Mariko Kuwabara, Hiroyuki Tashiro, Yasuo Terasawa, Kouji Osawa, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Development of Chronic Implantable Electrodes for Long-term Visual Evoked Potential Recording to Evaluate the Safety of Visual Prostheses in Rabbits, 生体医工学シンポジウム2016, 2016.09.
19. Hiroyuki Tashiro, Yasuo Terasawa, Mariko Kuwabara, Koji Osawa, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Development of an Evaluation System for Chronic Safety of Retinal Prostheses, 生体医工学シンポジウム2016, 2016.09.
20. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Kazutoshi Haraguchi, Fabrication and in-vitro characterization of novel hydrogel-based electrodes for visual prostheses, The Association for Research in Vision and Ophthalmology (ARVO) 2016 Annual Meeting, 2016.05, [URL].
21. Hiroyuki Tashiro, Yasuo Terasawa, Kazutoshi Haraguchi, Kouji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Feasibility study of high performance implantable stimulation electrode with nanocomposite gel coating for brain-machine interface (BMI) device, International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS and Applications 2015 (Bio4Apps 2015), 2015.12.
22. Hiroyuki Tashiro, Yasuo Terasawa, Kouji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Safety requirements of active implantable medical device, such as retinal prosthesis, at the stage of preclinical development, 2015 Japan-Taiwan Joint Workshop on Retinal Prostesis, 2015.10.
23. Hiroyuki Tashiro, Yasuo Terasawa, Kouji Osawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Current state of the development of retinal prosthesis with Suprachoroidal- Transretinal Stimulation, 2014 Taiwan-Japan Joint Symposium, 2014.12.
24. , [URL].
25. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Oosawa, Motoki Ozawa, An Analysis of Abnormal Peak in Cyclic Voltammogram of Porous Platinum Electrode, 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society(EMBS), 2014.08, [URL].
26. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Charge Injection Capacities of Femtosecond Laser-induced Porous Electrodes measured in vitro and in vivo: Comparison between porous and smooth electrodes, The Association for Research in Vision and Ophthalmology(ARVO) 2014 Annual Meeting, 2014.05, [URL].
27. Hiroyuki Tashiro, Yasuo Terasawa, Yukari Nakano, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Takashi Tokuda, Jun Ohta, Takashi Fujikado, Safety Assessment of Chronic Suprachoroidal-Transretinal Stimulation in Normal Rabbits by the Femtosecond Laserinduced Porous Electrodes, The Association for Research in Vision and Ophthalmology(ARVO) 2014 Annual Meeting, 2014.05, [URL].
28. Yasuo Terasawa, Hiroyuki Tashiro, Kouji Oosawa, Yukari Nakano, Motoki Ozawa, Safety Assessment of Semichronic Suprachoroidal Electrical Stimulation to Rabbit Retina, The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’13), 2013.07.
29. Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, Kouji Osawa, Motoki Ozawa, In vivo chronological observation of electrochemical properties of porous electrodes with chronic suprachoroidal-transretinal stimulation, The Association for Research in Vision and Ophthalmology(ARVO) 2013 Annual Meeting, 2013.05, [URL].
30. Yasuo Terasawa, Hiroyuki Tashiro, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Jun Ohta, Takashi Fujikado, Porous Platinum Electrodes for Retinal Prostheses, The 2012 Association for Research in Vision and Ophthalmology Annual Meeting (ARVO2012 Annual Meeting), 2012.05, [URL].
31. Hiroyuki Tashiro, Yasuo Terasawa, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Jun Ohta, Takashi Fujikado, In vivo Characterization of Electrochemically-Treated Platinum Bulk Electrodes for Retinal Prostheses, The 2012 Association for Research in Vision and Ophthalmology Annual Meeting (ARVO2012 Annual Meeting), 2012.05, [URL].
32. Hiroyuki Tashiro, Yasuo Terasawa, Masayuki Shinomiya, Motoki Ozawa, Toshihiko Noda, Jun Ohta, Long-term Suprachoroidal-transretinal Stimulation By The Bullet-shaped Platinum Electrodes In Normal Rabbits, The 2011 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, 2011.05, [URL].
33. Yasuo Terasawa, Hiroyuki Tashiro, Kouji Osawa, Motoki Ozawa, Toshihiko Noda, Jun Ohta, Fabrication of an Electrode Array with Thick Film Platinum Wire Using Laser Micromachining, The 2011 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, 2011.05, [URL].
34. Effect of Installation Position and illuminance level of the illumination in Ultrasound Room on Luminance Ratio of CRT Monitor of Ultrasound Equipment.
35. Yasuo Terasawa, Hiroyuki Tashiro, Mariko Taguchi, Kouji Osawa, Chisato Taki, Masayoshi Nakatani, Motoki Ozawa, Jun Ohta, Chronic recording of visually evoked cortical potentials for long-term evaluation of visual prothetheses, The 2nd Meeting of the International Federation for Artificial Organs, 2007.10.
36. An avaluation of charge injection capability of a platinum thin-film electrode for the artificial vison system.
37. Establishment of electrode impedance measurement method in vivo for the artificial vision system.
Membership in Academic Society
  • IEEE Engineering in Medicine and Biology Society (EMBS)
  • The Association for Research in Vision and Ophthalmology (ARVO)
  • Japan Society for Artificial Organs
  • Japanese Society for Medical and Biological Engineering
Awards
  • Paper Award (Sakamoto Award), Japanese Society for Medical and Biological Engineering
Educational
Educational Activities
I instruct teach medical engineering, medical informatics, and clinical physiology.
Social
Professional and Outreach Activities
I assist research and development of medical devices as a consulting engineer..