九州大学 研究者情報
論文一覧
荻野 洋一郎(おぎの よういちろう) データ更新日:2024.04.18

准教授 /  歯学研究院 歯学部門 口腔機能修復学講座クラウンブリッジ補綴学分野


原著論文
1. Yoshioka K, Ogino Y, Kawasaki M, Ayukawa Y., An observational study of oral functions in patients aged from 20 to 49 years., J Oral Sci., 10.2334/josnusd.23-0311., 66, 1, 75-78, 2024.01, Purpose: The purpose of this study was to analyze oral functions (MOF: maximum occlusal force; MTP: maximum tongue pressure; and MF: masticatory function) in Eichner A subjects aged from 20 to 49 years.

Methods: The data of three oral functions in Eichner A patients aged from 20 to 49 years were extracted. The mean values, subjects with lower values than the thresholds, and the differences among ages, and between sexes were investigated retrospectively.

Results: Although the mean values of these oral functions in 183 subjects were higher than the thresholds, the numbers of the subjects with lower values than the thresholds were 30 in MTP, 19 in MOF, and only three in MF. No significant effects of ages on all oral functions were identified and all functions in males were significantly higher than those in females. The subjects whose two functions were lower than the thresholds were nine females, eight of whom were associated with malalignment.

Conclusion: Although the mean values of oral functions were higher than the thresholds, some patients showed lower values, especially in MOF and MTP, even though they were unaware of any inconvenience. Patients with malalignment might be associated with declined oral functions.

Keywords: malalignment; masticatory function; maximum occlusal force; maximum tongue pressure; middle-aged population; young adulthood..
2. Kawasaki M, Ogino Y, Moroi R, Ayukawa Y., Comprehensive Analyses of Masticatory Function in Maxillectomy Patients with Functioning Removable Prostheses: A Retrospective Cross-Sectional Study.
, J Clin Med. , 10.3390/jcm12155117., 12, 15, 5117-5117, 2023.08, The aim of this retrospective cross-sectional study was to comprehensively assess masticatory function in maxillectomy patients with functioning removable prostheses. Their general and oral profiles, the measurement values of their oral functions, including masticatory function, and the history of tumor therapy were extracted from medical charts. The correlations of masticatory function with numerical data and the effects of tumor therapy-related factors on masticatory function were evaluated. In addition, a stepwise conditional logistic regression analysis was performed to identify the potential predictive factors comprehensively. The data from 55 maxillectomy patients revealed that the median value of masticatory function (138.0 mg/dL) was higher than the threshold (100.0 mg/dL) based on the concept of oral hypofunction. Moderate correlations of masticatory function with the number of remaining teeth, the number of functioning occlusal supports, and maximum occlusal force were found, as well as a weak correlation with maximum tongue pressure. These variables also showed statistically significant coefficients (p
3. Tanaka, K, Tsuchiya, A, Ogino, Y, Ayukawa, Y, Ishikawa, K., Comparison of calcite and vaterite as precursors for CO3Ap artificial bone fabrication through a dissolution–precipitation reaction, Ceramics International, 2022, 48(18), pp. 26425–26431, 2022.09, Carbonate apatite (CO3Ap) artificial bone is fabricated in an aqueous solution using calcium carbonate as a precursor. CO3Ap has attracted attention because it demonstrates high osteoconductivity and can replace a damaged bone based on the bone remodeling process. This study aims to compare vaterite and calcite, which are metastable and stable polymorphs of calcium carbonate, respectively, as precursors. When the vaterite granules, which have higher solubility and consist of smaller crystals than calcite, prepared from calcium oxide granules were immersed in disodium hydrogen phosphate solution, the compositional transformation to CO3Ap was quicker than that of calcite. Based on the investigations on rabbit femurs, it was observed that the remodeling of CO3Ap to a new bone was faster when vaterite was used as a precursor compared to when calcite was used as a precursor. It is concluded that vaterite can be a better precursor than calcite for CO3Ap artificial bone fabrication. .
4. Imai M, Ogino Y, Tanaka H, Koyano K, Ayukawa Y, Toyoshima T., Primary stability of different implant macrodesigns in a sinus floor elevation simulated model: an ex vivo study, BMC Oral Health. 2022 Aug 8;22(1):332. , doi: 10.1186/s12903-022-02345-5., 2022.08.
5. 荻野洋一郎, 下顎辺縁切除患者に顎義歯の設計変更で対応した症例, 顎顔面補綴
MAXILLOFACIAL PROSTHETICS
, 2021.12.
6. Ogino Y, Ayukawa Y, Tachikawa N, Shimogishi M, Miyamoto Y, Kudoh K, Fukuda N, Ishikawa K, Koyano K., Staged Sinus Floor Elevation Using Novel Low-Crystalline Carbonate Apatite Granules: Prospective Results after 3-Year Functional Loading., Materials (Basel)., doi: 10.3390/ma14195760., 14, 19, 5760, 2021.10, The aim of this study was to evaluate clinical outcomes of staged sinus floor elevation (SFE) using novel low-crystalline carbonate apatite (CO3Ap) granules. Patients who needed SFE for implant placement were recruited into this clinical trial. A staged procedure (lateral window technique using CO3Ap granules, followed by implant placement after 7 ± 2 months) was employed in 13 patients. Bone-height increase and insertion torque values (ITVs) were assessed along with histological evaluation. The survival and success rates of 3-year functioning implants were also evaluated. Mean of bone-height increase after SFE using CO3Ap granules was 7.2 ± 2.5 mm and this increase allowed implant placement in all cases (17 implants). Mean of ITV was 25.1 ± 13.2 Ncm and primary stability was achieved successfully in all cases. Histological analyses revealed mature new bone formation (36.8 ± 17.3%) and residual CO3Ap granules (16.2 ± 10.1%) in the compartment after SFE. The survival and success rates after 3-year functional loading were 100% and no complications were found. These results clearly indicate the clinical usefulness of CO3Ap granules for SFE..
7. Murakami K, Ayukawa Y, Ogino Y, Nakagawa A, Horikawa T, Yamaguchi E,    Takaki K, Koyano K. , Clinical effectiveness of implant support for distal extension removable partial dentures: functional evaluation using occlusal force measurement and masticatory efficiency., Int J Implant Dent., doi: 10.1186/s40729-021-00381-4., 7, 1, 101, 2021.10.
8. Ogino Y, Suzuki H, Ayukawa Y, Ueno Y, Jinnouchi A, Koyano K., Masticatory performance and other oral functions in commu, J Oral Sci., doi: 10.2334/josnusd.21-0265., 63, 4, 330-333, 2021.10.
9. Ogino Y, Suzuki H, Ayukawa Y, Jinnouchi A, Koyano K., Analyses of Swallowing Function and Its Related Factors in Community-Dwelling Elderly Patients: A Case-Control Study., J Clin Med., doi: 10.3390/jcm10153437., 10, 15, 3437, 2021.08.
10. 大木郷資,荻野洋一郎,今井実喜生,上田将之,木下康平,松村英尚,古谷野潔, マウスガードの咬合接触範囲が起立動作能力に与える影響についての検討, スポーツ歯学, 2021年25巻1号,8-13, 2021.08.
11. Kinoshita K, Ogino Y, Oki K, Yamasaki Y, Tsukiyama Y, Ayukawa Y, Koyano K., A Prospective Comparative Study of Mastication Predominance and Masticatory Performance in Kennedy Class I Patients., Healthcare (Basel). , doi: 10.3390/healthcare9060660., 9, 6, 660, 2021.06.
12. Oki K, Ogino Y, Takamoto Y, Imai M, Takemura Y, Ayukawa Y, Koyano K., The Significance of Posterior Occlusal Support of Teeth and Removable Prostheses in Oral Functions and Standing Motion., Int J Environ Res Public Health. , doi: 10.3390/ijerph18136776., 18, 13, 6776, 2021.06.
13. Ogino Y, Fujikawa N, Koga S, Moroi R, Koyano K. , A retrospective cross-sectional analysis of swallowing and tongue functions in maxillectomy patients., Support Care Cancer., doi: 10.1007/s00520-021-06186-w., 29, 10, 6079-6085, 2021.10, Purpose: To investigate the profiles of swallowing and tongue functions, and to identify factors influencing swallowing in maxillectomy patients.

Methods: Maxillectomy patients whose swallowing function defined by Eating Assessment Tool (EAT-10) score and tongue functions (oral diadochokinesis: ODK, maximum tongue pressure: MTP) with or without obturator prostheses had been evaluated were enrolled in this study. The effects of the history of radiotherapy and soft palate defect on swallowing function were evaluated. The effect of radiotherapy on oral dryness was also evaluated. To examine correlations of swallowing function with continuous variables, Spearman correlation coefficients were calculated.

Results: A total of 47 maxillectomy patients (23 males and 24 females, median age: 71 [IQR: 63-76]) were registered. The median value of EAT-10 scores was 3 [IQR: 0-14]. Patients with the history of radiotherapy, but not with soft palate defect, showed significantly declined swallowing function. ODK and MTP of patients wearing obturator prostheses were significantly improved. No significant effect of radiotherapy on oral dryness was found. A significant correlation was found between EAT-10 score and MTP (P = 0.04).

Conclusions: Swallowing function in maxillectomy patients was relatively impaired and the patients with the history of radiotherapy showed lower swallowing function. Obturator prostheses could contribute to the improvement of MTP and ODK (/ta/). MTP may play a crucial role in swallowing in maxillectomy patients..
14. Ogino Y, Matsushita Y, Sasaki M, Ayukawa Y, Koyano K., A 3-Year Prospective Study on Radiographic Marginal Bone Evaluation Around Platform-Shifting Implants with Internal Conical Connections., Int J Oral Maxillofac Implants. 2021 May-Jun;36(3):574-580.
, doi: 10.11607/jomi.8425., 36, 3, 574-580, 2021.06.
15. Kihara M, Ogino Y, Matsushita Y, Morita T, Sawae Y, Ayukawa Y, Koyano K., In Vitro Assessment of the Effect of Implant Position on Biomechanical Behaviors of Implant-Supported Removable Partial Dentures in Kennedy Class II Condition, MATERIALS, 10.3390/ma14092145, 14, 9, 2021.05.
16. Oki K, Ogino Y, Tsukiyama Y, Yamasaki Y, Koyano K, The impacts of prosthetic interventions on mastication predominance in Kennedy Class Ⅱ patients., J Prosthodont Res., doi: 10.2186/jpr.JPR_D_20_00055., 65, 3, 327-331, 2021.08.
17. Haraguchi T, Ayukawa Y, Shibata Y, Takeshita T, Atsuta I, Ogino Y, Yasunami N, Yamashita Y, Koyano K., Effect of Calcium Chloride Hydrothermal Treatment of Titanium on Protein, Cellular, and Bacterial Adhesion Properties.
, J Clin Med. , doi: 10.3390/jcm9082627., 13, 9, 2020.08.
18. Koga S, Ogino Y, Fujikawa N, Ueno M, Kotaki Y, Koyano K., Oral health-related quality of life and oral hygiene condition in patients with maxillofacial defects: A retrospective analysis.
, J Prosthodont Res., 10.1016/j.jpor.2019.11.003., 2020.02, Purpose: The purpose of this study was to evaluate the effect of oral rehabilitation (maxillofacial prosthetic intervention and oral hygiene instruction) on oral health-related Quality of Life (OHRQoL) and oral hygiene condition in patients with maxillofacial defects and to explore the correlation between them in these patients.Methods: Twenty-five patients with maxillofacial defects who had been treated since April 2016 to March 2018 were included in this study. The scores of the Oral Health Impact Profile (OHIP) and O’Leary’s Plaque Control Record (PCR) were also identified as the scores of OHRQoL and oral hygiene condition, respectively. Statistical analyses were performed to compare between the scores of “pre” and “post” prosthetic treatment and to evaluate patient-related factors influencing these variables (age, the number of residual teeth and occlusal supports, and occlusal units (OUs)). The effect of combined chemo-radiotherapy (CRT) on each score was also assessed statistically. Furthermore, the correlation of OHIP and PCR scores was explored statistically.Results: Both oral rehabilitations could significantly improve OHIP and PCR scores. Significant correlations of the change of OHIP scores with age and OUs were detected. CRT had no significant effect on OHIP and PCR scores. No correlations between OHIP and PCR were observed. Conclusions: Although oral rehabilitation such as maxillofacial prosthetic treatment and oral hygiene instruction would be highly effective for improvement of OHRQoL and oral hygiene condition in patients with maxillofacial defects, there was no correlation between them..
19. 古賀小百合,荻野洋一郎,藤川夏恵,上野真智子,古谷野潔, 顎補綴患者への口腔衛生指導の効果—PCR による比較検証—, 顎顔面補綴 2019, 42(2), 78-82, 42, 2, 78-82, 2019.12.
20. Matsuzaki T, Ayukawa Y, Matsushita Y, Sakai N, Matsuzaki M, Masuzaki T, Haraguchi T, Ogino Y, Koyano K., Effect of post-osseointegration loading magnitude on the dynamics of peri-implant bone: a finite element analysis and in vivo study.
, J Prosthodont Res., doi: 10.1016/j.jpor.2018.10.009., 63, 4, 453-459, 2019.10.
21. 鈴木宏樹 荻野洋一郎 熱田 生, 「噛める」から「食べられる」を目指して―舌圧の重要性を再考する―, ザ・クインテッセンス 2019年1月号, 2019.01.
22. Kudoh K, Fukuda N, Kasugai S, Tachikawa N, Koyano K, Matsushita Y, Ogino Y, Ishikawa K, Miyamoto Y., Maxillary Sinus Floor Augmentation Using Low-Crystalline Carbonate Apatite Granules With Simultaneous Implant Installation: First-in-Human Clinical Trial., J Oral Maxillofac Surg., doi: 10.1016/j.joms.2018.11.026., 77, 5, 985e1-985e11, 2019.05, Purpose: Carbonate apatite (CO3Ap), an inorganic component of human bone, can be fabricated in chemically pure form from calcium carbonate block via a dissolution-precipitation reaction. A first-in-human clinical trial was conducted in which low-crystalline CO3Ap granules were evaluated for safety and efficacy in sinus floor augmentation and simultaneous implant installation.

Materials and methods: Procedures were performed in 8 patients (9 implants) with 2 granule sizes: small (300 to 600 μm) and medium (600 to 1,000 μm). Panoramic radiographic assessment was performed immediately after augmentation, 7 ± 2 months after augmentation, 6 ± 2 months after prosthetic loading, and 12 ± 2 months after prosthetic loading.

Results: Postoperative healing was uniformly uneventful, with no abnormal bleeding, pain, or swelling, and all implants achieved successful osseointegration. The mean residual maxillary molar bone height was 5.2 ± 0.8 mm preoperatively and increased to 14.0 ± 1.9 mm after augmentation. Implants 9.0 to 11.5 mm in length were placed. The post-augmentation height decreased to 12.4 ± 1.3 mm at 7 ± 2 months; after prosthetic loading, it decreased to 11.9 ± 0.8 mm at 6 ± 2 months and 11.7 ± 0.6 mm at 12 ± 2 months. No abnormal bone resorption of the augmented areas was observed, and bone height supporting the implants was maintained. The overall implant survival rate was 100%, with no implant failures or complications during the first year.

Conclusions: Low-crystalline CO3Ap granules were useful and safe for sinus floor augmentation and simultaneous implant installation, providing a promising bone substitute for dental implant surgery..
23. Nishimura T, Ogino Y, Ayukawa Y, Koyano K., Influence of the wettability of different titanium surface topographies on initial cellular behavior., Dent Mater J., 2018.06, This study examined the influence of the time-dependent wettability of different surface topographies on initial cellular behavior. Titanium disks with smooth topography (SM) and three kinds of rough topography (sandblasted (SA), microtopography (M) and nanotopography (N)) were prepared. Time-dependent changes in surface wettability were observed in all surfaces as shown in previous studies. On SM surfaces, hydrophobic alteration influenced cell spreading and the activity of RhoA (a small GTPase protein of the Rho family), while no alterations were observed on rough surfaces except for the number of adherent cells. Serum adsorption could recover these functional deteriorations by hydrophobic alteration. These findings suggest that surface topography is a more potent regulator in initial cellular behaviors such as cell spreading and RhoA activation than surface wettability..
24. Gunge H, Ogino Y, Kihara M, Tsukiyama Y, Koyano K., Retrospective clinical evaluation of posterior monolithic zirconia restorations after 1 to 3.5 years of clinical service., J Oral Sci., 24, 60, 154-158, 2018.03.
25. Kaku T, Ogino Y, Matsushita Y, Koyano K., Technique for identifying keratinized gingival tissue and soft tissue morphology on 3-dimensional implant-planning software images., J Prosthet Dent., doi: 10.1016/j.prosdent., 116, 1, 21-24, 2016.05.
26. Nagasawa M, Cooper LF, Ogino Y, Mendonca D, Liang R, Yang S, Mendonca G, Uoshima K., Topography Influences Adherent Cell Regulation of Osteoclastogenesis, J Dent Res., 10.1177/0022034515616760, 95, 3, 319-326, 2016.03.
27. YOICHIRO OGINO, Ruiwei Liang, Daniela Mendonca, Gustavo Mendonca, Masako Nagasawa, kiyoshi koyano, Lyndon F. Cooper, RhoA-Mediated Functions in C3H10T1/2 Osteoprogenitors Are Substrate Topography-Dependent., J Cell Physiol, doi: 10.1002/jcp.25100., 231, 3, 568-575, 2016.03.
28. 荻野 洋一郎, 鮎川 保則, 富田陽子, 古谷野 潔, Prosthetic aspects in adult osteopetrosis., J Prosthet Dent., 2014.10, Osteopetrosis (OP) is a rare condition characterized by skeletal sclerosis caused by dysfunctional osteoclasts. Though many reports have described severe infantile-malignant autosomal recessive OP, few have described the prosthetic management of adult OP. This report discusses the prosthetic treatment of adult OP. Although prosthodontists should try to reconstruct occlusal function as much as possible, a conservative prosthodontic approach may be a reasonable and recommended treatment option for minimizing the risk of further osteomyelitis and osteonecrosis..
29. YOICHIRO OGINO, Kihara Masafumi, Junichi Yamda, Kohei Toriya, kiyoshi koyano, Implant Treatments for Edentulous Maxilla with Anterior Hyperfunction., J Oral Implantol., doi: 10.1563/AAID-JOI-D-13-00123. , 41, 6, 731-735, 2015.12.
30. Daisuke Kondo, YOICHIRO OGINO, Yasunori AYUKAWA, Shinji Sakai, KOEI KAWAKAMI, kiyoshi koyano, Bone Regeneration of Tibial Defects in Rats with Enzymatic Hydrogelation of Gelatin Derivative and Recombinant Human Platelet-Derived Growth Factor-BB Complex, INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS, 28, 5, 1377-1385, 2013.09.
31. YOICHIRO OGINO, 骨格性下顎前突を伴ったEichnerC2症例(上顎無菌顎)に対する補綴治療., 日本補綴歯科学会誌, 2013.04.
32. ATSUTA IKIRU, Yasunori AYUKAWA, Akihiro Furuhashi, YOICHIRO OGINO, Moriyama Yasuko, Yoshihiro Tsukiyama, kiyoshi koyano, In Vivo and In Vitro Studies of Epithelial Cell Behavior around Titanium Implants with Machined and Rough Surfaces., Clin Implant Dent Relat Res. , 10.1111/cid.12043, 2013.02.
33. Atsuta I, Ayukawa Y, Ogino Y, Moriyama Y, Koyano K. , Evaluations of epithelial sealing and peri-implant epithelial down-growth around “step-type” implants. , Clin Oral Implants Res, 2011.04.
34. Moriyama Y. Ayukawa Y. Ogino Y. Atsuta I. Todo M. Takao Y. Koyano K. , Local application of fluvastatin improves peri-implant bone quantity and mechanical properties: a rodent study. , Acta Biomaterialia. 6(4):1610-8, 2010 Apr. , 2010.04.
35. Masuzaki T, Ayukawa Y, Moriyama Y, Jinno Y, Atsuta I, Ogino Y, Koyano K., The effect of a single remote injection of statin-impregnated poly (lactic-co-glycolic acid) microspheres on osteogenesis around titanium implants in rat tibia, Biomaterials, 31(12): 3327-3334, 2010 Apr., 2010.04.
36. Ayukawa Y, Ogino Y, Moriyama Y, Atsuta I, Jinno Y, Kihara M, Tsukiyama Y, Koyano K., Simvastatin enhances bone formation around titanium implants in rat tibiae , Journal of Oral Rehabilitation, 37, 2, 123-130, 2010.02.
37. Jinno Y. Ayukawa Y. Ogino Y. Atsuta I. Tsukiyama Y. Koyano K. , Vertical bone augmentation with fluvastatin in an injectable delivery system: a rat study. , Clinical Oral Implants Research., 20(8):756-60, 2009.08.
38. Ogino Y. Ayukawa Y. Kukita T. Atsuta I. Koyano K. , Platelet-rich plasma suppresses osteoclastogenesis by promoting the secretion of osteoprotegerin.

, Journal of Periodontal Research, 44(2):217-24, 2009 Apr. , 2009.04.
39. Ayukawa Y. Yasukawa E. Moriyama Y. Ogino Y. Wada H. Atsuta I. Koyano K. , Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats.
, Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics
, . 107(3):336-42, 2009 Mar. , 2009.03.
40. Yoichiro Ogino, Kohei Toriya, Yasunori Ayukawa, Kiyoshi Koyano, Prosthetic and Surgical Managements of Peri-implantitis at the Flap Reconstruction Site., Prosthodontic Research & Practice Vol.7 No.2, 2008, Vol.7 No.2, 231-233, 2008, 2008.07.
41. Moriyama Y. Ayukawa Y. Ogino Y. Atsuta I. Koyano K. , Topical application of statin affects bone healing around implants., Clinical Oral Implants Research., Clinical Oral Implants Research. 19(6):600-5, 2008 Jun., 2008.07.
42. Yoichiro Ogino,Yasunori Ayukawa,Toshio Kukita,Kiyoshi Koyano, The contribution of platelet-derived growth factor, transforming growth factor-β1 and insulin-like growth factor-I in platelet-rich plasma (PRP) to the proliferation of osteoblast-like cells., Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics., 2006.05.
43. Yoichiro Ogino, DDS, PhD,a Yasunori Ayukawa, DDS, PhD,b Yoshihiro Tsukiyama, DDS, PhD,c, The effect of platelet-rich plasma on the cellular response of rat bone
marrow cells in vitro, Oral Surg Oral Med Oral Pathol Oral Radiol
Endod
, 10.1016/j.tripleo.2005.03.007, 100, 3, 302-307, Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 2005;100:302-7, 2005.10.

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