| Takeshi Hirota | Last modified date：2024.04.10 |
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https://kyushu-u.elsevierpure.com/en/persons/takeshi-hirota
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Academic Degree
Ph. D.
Field of Specialization
Clinical Pharmacokinetics
Outline Activities
Pharmacogenomics of drug metabolizing enzymes and transporters
Research
Research Interests
Membership in Academic Society
- Nucleosome positioning and the expression mechanisms of drug transporter genes in human kidney
keyword : nucleosome positioning, DNA methylation, drug transporter
2013.12. - Novel blood-based biomarkers associated with the expressions of pharmacokinetics related genes
keyword : biomarker, exosome, microRNA, DNA methylation, immunoprecipitation
2010.04. - Identification of a transcriptional enhancer element upstream from pharmacokinetics related genes by chromosome conformation capture assay
keyword : 3C assay, enhancer, CYP3A4
2010.04. - Mechanisms of microRNA regulation in pharmacokinetics related genes
keyword : pharmacokinetics, microRNA, DNA methylation, histone modification
2006.04. - Epigenetic regulation of gene expression in pharmacokinetics
keyword : pharmacokinetics, epigenetics, DNA methylation, histone modification
2003.04. - Genetic polymorphisms of Pharmacokinetics related genes
keyword : pharmacokinetics, polymorphisms
2000.04.
- Japanese Society of Pharmaceutical Health Care and Sciences
- The Pharmaceutical Society of Japan
- The Japanese Society for the Study of Xenobiotics
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