Kyushu University Academic Staff Educational and Research Activities Database
Researcher information (To researchers) Need Help? How to update
Hisao Kondo Last modified date:2023.05.16

Professor / Department of Molecular Cell Biology
Department of Molecular Biology
Faculty of Medical Sciences

Graduate School

E-Mail *Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Ph.D in Medicine
Field of Specialization
Cell Biology
Outline Activities
I have been investigating the biogenesis of organelles, e.g., the Golgi apparatus and ER. Especially, we focus on the clarification of the p97ATPase-mediated membrane fusion.
Research Interests
  • Molecular mechanism of the Golgi biogenesis.
    keyword : p97ATPase, membrane fusion, Golgi
Academic Activities
1. Totsukawa G, Kaneko Y, Uchiyama K, Toh H, Tamura K, Kondo H, VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion., EMBO J, 30, 17, 3455-3474, 2011.09.
2. Briggs LC, Baldwin GS, Miyata N, Kondo H, Zhang X, and Freemont PS., Analysis of nucleotide binding to p97 reveals the properties of a tandem AAA hexameric ATPase., J Biol Chem, 283:13745-13752., 2008.04.
3. Uchiyama K, Totsukawa G, Puhka M, Kaneko Y, Jokitalo E, Dreveny I, Beuron F, Zhang X, Freemont P, and Kondo H., p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis., Developmental Cell, 11: 803-816., 2007.01.
4. Beuron F, Dreveny I, Yuan X, Pye VE, Mckeown C, Briggs LC, Cliff MJ, Kaneko Y, Wallis R, Isaacson RL, Ladbury JE, Matthews SJ, Kondo H, Zhang X, Freemont PS., Conformational changes in the AAA ATPase p97-p47 adaptor complex., EMBO J, 25: 1967-1976., 2006.01.
5. Dreveny I, Kondo H, Uchiyama K, Shaw A, Zhang X and Freemont PS., Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47., EMBO J, 23: 1030-1039., 2004.01.
6. . Uchiyama K, Jokitalo E, Lindman M, Jackman M, Kano F, Murata M, Zhang X and Kondo H., The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle., J Cell Biology, 161: 1067-1079., 2003.01.
7. Uchiyama K, Jokitalo E, Kano F, Murata M, Zhang X, Canas B, Newman R, Rabouille C, Pappin D, Freemont P and Kondo H., VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo., J Cell Biology, 159: 855-866., 2002.01.
8. Zhang X, Shaw A, Bates PA, Newman RH, Gowen B, Orlova E, Gorman MA, Kondo H, Dokurno P, Lally J, Leonard G, Meyer H, van Heel M and Freemont PS., Structure of the AAA ATPase p97., Molecular Cell, 6: 1473-1484., 2000.01.
9. . Kondo H, Rabouille C ( Joint first authorship), Newman R, Hui N, Freemont P and Warren G., Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro., Cell, 92: 603-610., 1998.01.
10. Kondo H, Rabouille C, Newman R, Levine TP, Pappin D, Freemont P and Warren G., p47 is a cofactor for p97-mediated membrane fusion., Nature, 388: 75-78., 1997.01.
Educational Activities
I have been teaching medical students.
Professional and Outreach Activities
Colaboration with Imperial College group.