Kyushu University Academic Staff Educational and Research Activities Database
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Koji Yoshimoto Last modified date:2022.09.14

Professor / Deaprtment of Neurosurgery, Graduate School of Medical Sciences
Neurological Institute
Faculty of Medical Sciences

Graduate School

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 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
M.D.,Ph. D.
Country of degree conferring institution (Overseas)
Field of Specialization
Total Priod of education and research career in the foreign country
Research Interests
  • Elucidation of metabolic mechanisms of brain tumors
    keyword : Brain tumors  Metabolic mechanisms
  • Dissection of molecular mechanism of glioblastoma and application to the treatment based on transcriptome analysis
    keyword : glioblastoma, transcriptome
  • COX2 expression and its biological function in malignant glioma
    keyword : COX2、malignant glioma
  • Development of a new therapeutic stratergy for GBM treatment targeting the DNA repair system
    keyword : GBM DNA reapir
  • The development of new therapeutic stratergy targeted at brain tumor stem cell
    keyword : Brain tumor stem cell
  • The research about mesenchymal stem cell toward brain tumor
    keyword : mesencymal stem cell
  • The genetic and signal pathway analysis fo brain tumors
    keyword : brain tumor signalling pathway
Academic Activities
1. Hideki Murata, Koji Yoshimoto, Detection of proneural/mesenchymal marker xpression in glioblastoma: temporospatial dynamics and association with chromatin-modifying gene expression, J Neurooncol. 2015;125(1):33-41. , 2016.06.
2. Koji Yoshimoto, Dual optical channel three-dimensional neuroendoscopy: Clinical application as an assistive technique in endoscopic endonasal surgery, 6, 45-50, 2016.06.
3. Yoshimoto K, Ma X, Guan Y, Mizoguchi M, Nakamizo A, Amano T, Hata N, Kuga D,Sasaki T, Expression of stem cell marker and receptor kinase genes in glioblastoma tissue quantified by real-time RT-PCR, Brain Tumor Pahology, 28, 4, 291-6, 2011.10.
4. Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson D, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner D, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS:, Detection of EGFRvIII in routinely processed glioblastoma clinical samples, Clinical Cancer Research, 14(2): 488-493, 2008.01.
1. Koji Yoshimoto, PGFRA amplification is asignificant prognostic marker in patients with IDH wild-type glioblastoma multiforme, WFNOS2022 SEOUL, 2022.03.
2. Koji Yoshimoto, HDAC7 as a possible therapeutic target for mesenchymal glioblastoma, 21Th International Conference on Brain Tumor Research and Therapy , 2016.04.
3. Koji Yoshimoto, Activation of the ATM/Chk2 pathway in intracranial germinomas, 4Th International CNS Germ Cell Tumor Symposium, 2015.04.
4. 吉本 幸司, Endoscopic transsphenoidal surgery
-Early clinical experiences of 3D endoscopy-
, Italian-Japanese Joint Meeting 2012, 2012.11.
5. 吉本 幸司, Diagnostic significance of microRNA and gene expression in glioma patients., The 4th International Symposium of Brain Tumor Pathology, 2012.05.