


Kawabe Yoshinori | Last modified date:2023.01.04 |

Associate Professor /
Molecular and Biochemical Systems Engineering
Department of Chemical Engineering
Faculty of Engineering
Department of Chemical Engineering
Faculty of Engineering
Graduate School
Undergraduate School
E-Mail *Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
Homepage
https://kyushu-u.pure.elsevier.com/en/persons/kawabe-yoshinori
Reseacher Profiling Tool Kyushu University Pure
http://www.chem-eng.kyushu-u.ac.jp/lab3/index.html
Phone
092-802-2753
Fax
092-802-2793
Academic Degree
Doctor of Engineering, Nagoya University, Japan
Country of degree conferring institution (Overseas)
No
Field of Specialization
Biochemical Engineering
Total Priod of education and research career in the foreign country
00years02months
Research
Research Interests
Membership in Academic Society
- Development and application of microalgae biotechnology
keyword : Algae, Microalgae, Chlamydomonas reinhardtii, transgene integration, gene retargeting, recombinant protein production
2017.04. - Mass production sysytem for the biopharmaceutical proteins by transgenic avian bioreactor
keyword : transgenic avian bioreactor, biopharmaceuticals, recombinant proteins, monoclonal antibody, retroviral vector
2004.04. - development of maintainance and efficient derivation for pluripotential stem cells
keyword : pluripotential stem cells, genetically manipulated animals, feeder layer, tissue engineering
2008.04.
Books
1. | Yoshinori Kawabe, Masamichi Kamihira, Production of Antibody by Transgenic Avians. In: Al-Rubeai, M. (eds) Antibody Expression and Production. Cell Engineering, vol 7. Springer, Dordrecht., https://doi.org/10.1007/978-94-007-1257-7_6, pp121-141, 2011.04, [URL]. |
Papers
1. | Yoshinori Kawabe, Masamichi Kamihira, Novel cell lines derived from Chinese hamster kidney tissue, PLoS One, doi: 10.1371/journal.pone.0266061., 17, 3, e0266061, 2022.03, [URL]. |
2. | Guan Huang$, Yoshinori Kawabe$, Kazuki Shirakawa, Tatsuki Akiyama, Masamichi Kamihira ($Co-1st author), Novel transgenic Chlamydomonas reinhardtii strain with retargetable genomic transgene integration using Cre-loxP system , J Biosci Bioeng, https://doi.org/10.1016/j.jbiosc.2021.07.006, 132, 5, 469-478, 2021.07, [URL]. |
3. | Feiyang Zheng, Yoshinori Kawabe, Mai Murakami, Mamika Takahashi, Kyoka Nishihata, Souichiro Yoshida, Akira Ito, Masamichi Kamihira, LINE-1 vectors mediate recombinant antibody gene transfer by retrotransposition in Chinese hamster ovary cells, Biotechnol J, https://doi.org/10.1002/biot.202000620, 16, 7, e2000620, 2021.07, [URL]. |
4. | Ryusei Iwao, Yoshinori Kawabe, Mai Murakami, Akira Ito, Masamichi Kamihira, Targeted Knock-in of Transgenes into the CHO Cell Genome Using CRISPR-mediated Integration Systems, MATEC Web of Conferences, https://doi.org/10.1051/matecconf/202133307001, 333, 07001, The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019), 2021.01, [URL]. |
5. | Feiyang Zheng, Yoshinori Kawabe, Mai Murakami, Mamika Takahashi, Shoichiro Yoshida, Akira Ito, Masamichi Kamihira, Retrotransposon-mediated Gene Transfer for Animal Cells, MATEC Web of Conferences, https://doi.org/10.1051/matecconf/202133307002, 333, 07002, The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019), 2021.01, [URL]. |
6. | Kazuki Shirakawa, Yoshinori Kawabe, Guan Huang, Akira Ito, Masamichi Kamihira, Targeted Gene Integration into Nuclear Genome of Microalgae Using Cre/loxP Recombination System, MATEC Web of Conferences, https://doi.org/10.1051/matecconf/202133307003, 333, 07003, The 18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019), 2021.01, [URL]. |
7. | Ming Shi, Yoshinori Kawabe, Akira Ito, Masamichi Kamihira, Targeted knock-in into the OVA locus of chicken cells using CRISPR/Cas9 system with homology-independent targeted integration, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2019.09.011, 129, 3, 363-370, 2020.03, [URL]. |
8. | Yoshinori Kawabe, Shinya Komatsu, Shodai Komatsu, Mai Murakami, Akira Ito, Tetsushi Sakuma, Takahiro Nakamura, Takashi Yamamoto, Masamichi Kamihira, Targeted knock-in of an scFv-Fc antibody gene into the hprt locus of Chinese hamster ovary cells using CRISPR/Cas9 and CRIS-PITCh systems, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2017.12.003, 125, 5, 599-605, 2018.05, [URL]. |
9. | Yoshinori Kawabe, Takuya Shimomura, Shuohao Huang, Suguru Imanishi, Akira Ito, Masamichi Kamihira, Development of retroviral vectors capable of site-specific gene insertion together with protein delivery, BMC Proceedings, https://doi.org/10.1186/s12919-018-0097-x, 2018, 12(Suppl 1):P-327, 2018.03, [URL]. |
10. | Xue Wang, Yoshinori Kawabe, Takeshi Hada, Akira Ito, Masamichi Kamihira, Cre-mediated transgene integration in Chinese hamster ovary cells using minicircle DNA vectors, Biotechnology Journal, 10.1002/biot.201800063, 13, 7, e1800063, 2018.07, [URL]. |
11. | Xue Wang, Kawabe Yoshinori, Risa Kato, Takeshi Hada, Akira Ito, Yoshimasa Yamana, Masako Kondo, Masamichi Kamihira, Accumulative scFv-Fc antibody gene integration into the hprt chromosomal locus of Chinese hamster ovary cells, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2017.05.017, 124, 5, 583-590, 2017.11, [URL]. |
12. | Kawabe Yoshinori, Takanori Inao, Shodai Komatsu, Guan Huang, Akira Ito, Takeshi Omasa, Masamichi Kamihira, Improved recombinant antibody production by CHO cells using a production enhancer DNA element with repeated transgene integration at a predetermined chromosomal site, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2016.10.011, 123, 3, 390-397, 2017.03, [URL]. |
13. | Kawabe Yoshinori, Takuya Shimomura, Shuohao Huang, Suguru Imanishi, Akira Ito, Masamichi Kamihira, Targeted transgene insertion into the CHO cell genome using Cre recombinase-incorporating integrase-defective retroviral vectors, Biotechnology and Bioengineering, 10.1002/bit.25923, 113, 7, 1600-1610, 2016.07, [URL]. |
14. | Yoshinori Kawabe, Takanori Inao, Shodai Komatsu, Akira Ito, Masamichi Kamihira, Cre-mediated cellular modification for establishing producer CHO cells of recombinant scFv-Fc, BMC Proceedings, 10.1186/1753-6561-9-S9-P5, 9(Suppl 9):P5, 2015.12, [URL]. |
15. | Kawabe Yoshinori, Hirokatsu Makitsubo, Yujiro Kameyama, Shuohao Huang, Akira Ito, Masamichi Kamihira, Repeated integration of antibody genes into a pre-selected chromosomal locus of CHO cells using an accumulative site-specific gene integration system, Cytotechnology, 10.1007/s10616-011-9397-y, 64, 3, 267-279, 2012.05, [URL]. |
16. | Hirokazu Obayashi, Kawabe Yoshinori, Hirokatsu Makitsubo, Ryoko Watanabe, Yujiro Kameyama, Shuohao Huang, Yuta Takenouchi, Akira Ito, Masamichi Kamihira, Accumulative gene integration into a pre-determined site using Cre/loxP, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2011.10.027, 113, 3, 381-388, 2012.03, [URL]. |
17. | Kawabe Y, Hayashida Y, Numata K, Harada S, Hayashida Y, Ito A, Kamihira M, Oral immunotherapy for pollen allergy using T-cell epitope-containing egg white derived from genetically manipulated chickens, PLOS ONE, doi:10.1371/journal.pone.0048512, 7, 10, e48512, 2012.10, [URL]. |
18. | Yujiro Kameyama, Kawabe Yoshinori, Akira Ito, Masamichi Kamihira, An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange, Biotechnology and Bioengineering, 10.1002/bit.22619, 105, 6, 1106-1114, 2010.04, [URL]. |
19. | Carlos Alberto Penno, Kawabe Yoshinori, Akira Ito, Masamichi Kamihira, Production of recombinant human erythropoietin/Fc fusion protein by genetically manipulated chickens, Transgenic Research, 10.1007/s11248-009-9310-z, 19, 2, 187-195, 2010.04, [URL]. |
20. | Kawabe Yoshinori, Tsutomu Naka, Hiroyuki Komatsu, Ken Ichi Nishijima, Shinji Iijima, Masamichi Kamihira, Retroviral Gene Transduction into Chicken Embryo Gonads through Blood Circulation, Journal of Bioscience and Bioengineering, 10.1263/jbb.106.598, 106, 6, 598-601, 2008.12, [URL]. |
21. | Kawabe Yoshinori, Tsutomu Naka, Naoko Ando-Noumi, Hiroyuki Matsumoto, Ken ichiro Ono, Ken ichi Nishijima, Masamichi Kamihira, Shinji Iijima, Transport of human immunoglobulin G and Fc-fusion proteins to chicken egg yolk, Journal of Bioscience and Bioengineering, 10.1263/jbb.102.518, 102, 6, 518-523, 2006.12, [URL]. |
22. | Kawabe Yoshinori, Masamichi Kamihira, Ken ichiro Ono, Kenji Kyogoku, Ken ichi Nishijima, Shinji Iijima, Production of scFv-Fc fusion protein using genetically manipulated quails, Journal of Bioscience and Bioengineering, 10.1263/jbb.102.297, 102, 4, 297-303, 2006.10, [URL]. |
23. | Yoshinori Kawabe, Akitsu Hotta, Ken-ichiro Ono, Kazuhisa Esaka, Ken-ichi Nishijima, Masamichi Kamihira, and Shinji Iijima, Production of chimeric antibodies by transgenic chicken bioreactor, Animal Cell Technology: Basic & Applied Aspects, https://doi.org/10.1007/1-4020-4457-7_42, 14, 307-314, 2006.05, [URL]. |
Presentations
- The Society of Biotechnology, Japan
- The Society of Chemical Engineers, Japan
- Japanese Association for Animal Cell Technology
- The Molecular Biology Society of Japan
Educational


Unauthorized reprint of the contents of this database is prohibited.
