


Kumamaru Wataru | Last modified date:2023.06.19 |

Lecturer /
Department of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University
Maxill Ofacial Surgery
Kyushu University Hospital
Maxill Ofacial Surgery
Kyushu University Hospital
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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/kumamaru-wataru
Reseacher Profiling Tool Kyushu University Pure
Phone
092-642-6452
Fax
092-642-6392
Academic Degree
A study on tumor-specific cytotoxic T lymphocytes in patients with oral squamous cell carcinoma
Country of degree conferring institution (Overseas)
Yes Doctor
Field of Specialization
oral surgery
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
research content:
Controlling metastatic lesions is an important part of improving cancer prognosis, in addition to controlling the primary lesion. we successfully established a cell line derived from lower gingival carcinoma (WK2) as well as a line derived from secondary cervical lymph node metastasis (WK3F) through primary cultures of tissue from a patient with oral squamous cell carcinoma. We then investigated the biological characteristics of the cancer cell lines from these primary and metastatic lesions and analyzed metastasis-related genes. Single cells were established from WK2 early preserved cells. We are analyzing cancer diversity at the single-cell level rather than the bulk. This method is expected to be useful for elucidating metastasis mechanisms and discovering therapeutic target genes.
Education content:
I give lectures and guidance on oral surgery to dental students and residents.
Controlling metastatic lesions is an important part of improving cancer prognosis, in addition to controlling the primary lesion. we successfully established a cell line derived from lower gingival carcinoma (WK2) as well as a line derived from secondary cervical lymph node metastasis (WK3F) through primary cultures of tissue from a patient with oral squamous cell carcinoma. We then investigated the biological characteristics of the cancer cell lines from these primary and metastatic lesions and analyzed metastasis-related genes. Single cells were established from WK2 early preserved cells. We are analyzing cancer diversity at the single-cell level rather than the bulk. This method is expected to be useful for elucidating metastasis mechanisms and discovering therapeutic target genes.
Education content:
I give lectures and guidance on oral surgery to dental students and residents.
Research
Research Interests
Membership in Academic Society
- Biological characterization and analysis of metastasis-related genes in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the oral region
keyword : cancer cell line, metastasis-related genes
2012.04~2022.03. - The development of cancer vaccine therapy with tailor-made medicine
keyword : tumor immunity, cytotoxic T lymphocytes
2009.04~2013.03. - The tumor immunotherapy and identification of cancer-associated antigen by use of improved cDNA library method
keyword : tumor immunity, cytotoxic T lymphocytes, cancer-associated antigen
2006.09~2009.03.
Reports
Papers
- Japan Society for Oral Tumors
- Japanese Stomatological Society
- Asian Journal of Oral and Maxillofacial Surgery
- Japanese Society of Oral and Maxillofacial Surgeons
- Japanese Society for Immunology
Educational
Educational Activities
I am in charge of student lectures, clinical preparatory exercises and OSCE.
I am teaching dental students and residents who came to training in oral surgery.
I am teaching dental students and residents who came to training in oral surgery.
Social


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