Kyushu University Academic Staff Educational and Research Activities Database
Researcher information (To researchers) Need Help? How to update
Yoji Hirano Last modified date:2019.08.19

Assistant Professor / Neuro-Psychiatry
Kyushu University Hospital

Graduate School
Administration Post

homepage project manager (content, design, etc) .
Academic Degree
M.D., Ph.D.
Country of degree conferring institution (Overseas)
Field of Specialization
Psychiatry / Clinical Neurophysiology
ORCID(Open Researcher and Contributor ID)
Total Priod of education and research career in the foreign country
Outline Activities
My main focus is to study oscillatory brain dynamics and neuroimaging abnormalities in patients with Schizophrenia and Bipolar disorder.
I'm also a member of ICD-11 field study and a core member of the ICD-11 SCI-11 team.
Research Interests
  • Detecting neural oscillation abnormalities during emotion regulation in patients with schizophrenia.
    keyword : Schizophrenia, Gamma oscillation, Neural oscillation, Emotion regulation
  • Comprehensive research on abnormal γ-band activity in first episode schizophrenia and clinical high risk group.
    keyword : First episode schizophrenia, clinical high risk group, γ-band activity
  • Evaluation of brain function on schizophrenia and bipolar disorder.
    keyword : schizophrenia, bipolar disorder, functional nouroimaging, MEG, cognitive function
Academic Activities
1. Naoya Oribe, Yoji Hirano, Elisabetta del Re, Larry J. Seidman, Raquelle I. Mesholam-Gately, Kristen A. Woodberry, Joanne D. Wojcik, Takefumi Ueno, Shigenobu Kanba, Toshiaki Onitsuka, Martha E. Shenton, Jill M. Goldstein, Margaret A. Niznikiewicz, Robert W. McCarley, Kevin M. Spencer, Progressive reduction of auditory evoked gamma in first episode schizophrenia but not clinical high risk individuals, Schizophrenia Research, 10.1016/j.schres.2019.03.025, 208, 145-152, 2019.06.
2. Yoji Hirano, Naoya Oribe, Shigenobu Kanba, Toshiaki Onitsuka, Paul G Nestor, Kevin M Spencer, Spontaneous Gamma Activity in Schizophrenia, JAMA Psychiatry, 10.1001/jamapsychiatry.2014.2642., 72, 8, 813-821, 2015.08, [URL], We found increased spontaneous gamma activity during auditory steady-state stimulation in schizophrenia (SZ), reflecting a disruption in the normal balance of excitation and inhibition. This phenomenon interacts with evoked oscillations, possibly contributing to the gamma ASSR deficit found in SZ. The similarity of increased spontaneous gamma power in SZ to the findings of increased spontaneous gamma power in animal models of NMDAR hypofunction suggests that spontaneous gamma power could serve as a biomarker for the integrity of NMDARs on parvalbumin-expressing inhibitory interneurons in humans and in animal models of neuropsychiatric disorders..
3. Shogo Hirano, Yoji Hirano, Toshihiko Maekawa, Choji Obayashi, Naoya Oribe, Toshihide Kuroki, Shigenobu Kanba, Toshiaki Onitsuka, Abnormal neural oscillatory activity to speech sounds in schizophrenia: A magnetoencephalography study, The Journal of Neuroscience, 10.1523/JNEUROSCI.5031-07.2008, 28, 19, 4897-4903, 2008.05, [URL].
4. Yoji Hirano, Shogo Hirano, Choji Obayashi, Naoya Oribe, Akira Monji, Kiyoto Kasai, Shigenobu Kanba, Toshiaki Onitsuka, Auditory gating deficit to human voices in schizophrenia: a MEG study, Schizophr Res, 10.1016/j.schres.2009.09.003., 117, 1, 61-67, 2010.03, [URL].
5. Yoji Hirano, Toshiaki Onitsuka, Toshihide Kuroki, Yuji Matsuki, Shogo Hirano, Toshihiko Maekawa, Shigenobu Kanba, Auditory sensory gating to the human voice: A preliminary MEG study, Psychiatry Research - Neuroimaging, 10.1016/j.pscychresns.2007.07.002, 163, 3, 260-269, 2008.08.
6. Naoya Oribe, Yoji Hirano, Shigenobu Kanba, Del Re E, Seidman L, Mesholam-Gately R, Goldstein JM, Shenton M, Spencer KM, McCarley RW, Niznikiewicz M, Progressive Reduction of Visual P300 Amplitude in Patients With First-Episode Schizophrenia: An ERP Study, Schizophr Bull, 10.1093/schbul/sbu083, 41, 460-470, 2015.03, [URL].
7. Naoya Oribe, Yoji Hirano, Shigenobu Kanba, Elisabetta C. del Re, Larry J. Seidman, Raquelle Mesholam-Gately, Kevin M. Spencer, Robert W. McCarley, Margaret A. Niznikiewicz, Early and late stages of visual processing in individuals in prodromal state and first episode schizophrenia: An ERP study, Schizophrenia Research, 10.1016/j.schres.2013.01.015, 146, 1-3, 95-102, 2013.05.
8. Itta Nakamura, Yoji Hirano, Naotoshi Ohara, Shogo Hirano, Takefumi Ueno, Rikako Tsuchimoto, Shigenobu Kanba, Toshiaki Onitsuka, Early Integration Processing between Faces and Vowel Sounds in Human Brain: An MEG Investigation, Neuropsychobiology, 10.1159/000377680, 71, 4, 187-195, 2015.06, [URL].
1. , [URL].
2. Yoji Hirano, Abnormal Neural Oscillation and Auditory Hallucination in Schizophrenia, The International Consortium on Hallucination Research 2018 KYOTO, 2018.09, [URL].
3. Yoji Hirano, Kevin Spencer, Abnormal cortical activities in psychosis: toward translational research, 生物学的精神医学会, 2018.09, [URL].
4. Yoji Hirano, Progressive spontaneous and synchrony gamma-band oscillation deficits in first episode schizophrenia., The 2018 Congress of The Schizophrenia International Research Society, 2018.04.
5. Yoji Hirano, Toshiaki Onitsuka, Kevin M Spencer, Abnormal cortical activities in psychosis: toward translational research, The 21st International Conference on Biomagnetism, 2018.08, [URL].
6. Yoji Hirano, Altered Gamma Oscillation Patterns During Name Recognition in Schizophrenia, 16th International Congress on Schizophrenia Research, 2016.03.
7. Yoji Hirano, Kevin Spencer, Reduced auditory evoked oscillations and underlying structural abnormality in Schizophrenia, Organization for Human Brain Mapping 2015, 2016.06.
Membership in Academic Society
  • Schizophrenia International Research Society
  • Society for Neuroscience
  • Societies of Biological Psychiatry
  • Society for Psychophysiological Research
  • Japanese Societies of Biological Psychiatry
  • World Federation of Societies of Biological Psychiatry
  • APSBMS Outstanding Research Award 2019
  • SIRS Young Investigator Award 2018
  • TSSR Award 2017
  • Fund Award for Brain Science 2015
  • JSBP Young Investigator Program Encouragement Award 2015
  • ICOSR Young Investigator Award 2015
Educational Activities
Clinical training/lecture for medical students and residents and interns.
Research training for graduate students using neuroimaging and electrophysiology techniques in psychosis.
Professional and Outreach Activities
ICD-11 Field Study & ICD-11 SCI-11 core team member. .