Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Hiroaki Niiro Last modified date:2021.06.28

Professor / Department of Medical Education / Department of Medical Education / Faculty of Medical Sciences


Papers
1. Higashioka K, Yoshimura M, Sakuragi T, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Horiuchi T, Akashi K, Niiro H, Human PD-1hiCD8+ T cells are a cellular source of IL-21 in rheumatoid arthritis, Front Immunol, 10.3389/fimmu.2021.654623, 12, 654623, 2021.03.
2. Nakayama T, Yoshimura M, Higashioka K, Miyawaki K, Ota Y, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Akashi K, Horiuchi T, Niiro H, Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis, Cell Immunol, 10.1016/j.cellimm.2020.104263., 360, 104263, 2021.02.
3. Higashioka K, Kikushige Y, Ayano M, Kimono Y, Mitoma H, Kikukawa M, Akahoshi M, Arinobu Y, Horiuchi T, Akashi K, Niiro H, Generation of a novel CD30+ B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis, Clin Exp Immunol, 10.1111/cei.13477, 2020.06.
4. Higashioka K, Ota Y, Maehara T, Moriyama M, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Horiuchi T, Nakamura S, Akashi K, Niiro H, Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease, BMC Immunol, 10.1186/s12865-020-00361-0, 2020.06.
5. Inokuchi S, Mitoma H, Kawano S, Nakano S, Ayano M, Kimoto Y, Akahoshi M, Arinobu Y, Tsukamoto H, Akashi K, Horiuchi T, Niiro H, Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells, J Immunol, 10.4049/jimmunol.1901304, 2020.04.
6. Takaki-Kuwahara A, Arinobu Y, Miyawaki K, Yamada H, Tsuzuki H, Irino K, Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Tsukamoto H, Horiuchi T, Niiro H, Akashi K, CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines, Arthritis Res Ther, 0.1186/s13075-019-1984-x, 21, 1, 198, 2019.08.
7. Nakaoka Y, Isobe M, Tanaka Y, Ishii T, Ooka S, Niiro H, Tamura N, Banno S, Yoshifuji H, Sakata Y, Kawakami A, Atsumi T, Furuta S, Kohsaka H, Suzuki K, Hara R, Maejima Y, Tsukamoto H, Takasaki Y, Yamashita K, Okada N, Yamakido S, Takei S, Yokota S, Nishimoto N, Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study, Rheumatology, 10.1093/rheumatology/kez630, 2020.01.
8. Ayano M, Tsukamoto H, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Miyamoto T, Horiuchi T, Niiro H, Nagafuji K, Harada M, Akashi K, CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan., Arthritis Res Ther, 10.1186/s13075-019-1823-0., 2019.01.
9. Otsuka Y, Kiyohara C, Kashiwado Y, Sawabe T, Nagano S, Kimoto Y, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T, Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study., PLoS One, 2018.04.
10. Wakasaki T, Niiro H, Jabbarzadeh-Tabrizi S, Ohashi M, Kimitsuki T, Nakagawa T, Komune S, Akashi K, Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration., BMC Neurosci , 10.1186/s12868-017-0382-z, 18, 64, 2017.06.
11. Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota S-I, Ota Y, Mitoma H, Akahoshi H, Mori Y, Iwasaki H, Niiro H, Tsukamoto H, Akashi K, Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes. , Immunology, 10.1111/imm.12667, 150, 1, 64-73, 2017.01.
12. Hidemi Nakagawa, Hiroaki Niiro, Kenji Ootaki, Brodalumab, a human anti-interleukin-17-receptor antibody in the treatment of Japanese patients with moderate-to-severe plaque psoriasis: Efficacy and safety results from a phase II randomized controlled study., J Dermatol Sci., 10.1016/j.jdermsci.2015.10.009, 81, 1, 44-52, 2016.01.
13. Tomomi Tsuru, Yoshiya Tanaka, Mitsumasa Kishimoto, Kazuyoshi Saito, Seiji Yoshizawa, Yoshinari Takasaki, Tomoya Miyamura, Hiroaki Niiro, Shinji Morimoto, Junichi Yamamoto, Rocio Lledo-Garcia, Jing Shao, Shuichiro Tatematsu, Osamu Togo, Takao Koike, Safety, Pharmacokinetics and Pharmacodynamics of Epratuzumab in Japanese Patients with Moderate-to-Severe Systemic Lupus Erythematosus: Results from a Phase 1/2 Randomized Study. , Mod Rheumatol., 10.3109/14397595.2015.1079292, 26, 1, 87-93, 2016.01.
14. 綾野 雅宏, 塚本 浩, 河野 健太郎, 上田 尚靖, 田中 淳, Hiroki Mitoma, Mitsuteru Akahoshi, Yojiro Arinobu, Hiroaki Niiro, Takahiko Horiuchi, koichi akashi, Increased CD226 Expression on CD8+ T Cells Is Associated with Upregulated Cytokine Production and Endothelial Cell Injury in Patients with Systemic Sclerosis., J Immunol., 10.4049/jimmunol.1403046, 195, 3, 892-900, 2015.08.
15. Nobuyuki Ono, Hiroaki Niiro, Akira Ueda, Takuya Sawabe, Hiroaki Nishizaka, Isao Furugo, Seigi Yoshizawa, Shigeru Yoshizawa, Hiroshi Tsukamoto, Chikako Kiyohara, Yoshifumi Tada, Takahiko Horiuchi, Characteristics of MPO-ANCA-positive granulomatosis with polyangiitis: a retrospective multi-center study in Japan, Rheumatol Int, 10.1007/s00296-014-3106-z, 35, 3, 555-559, 2015.03.
16. Kensuke Oryoji, Chikako Kiyohara, Takahiko Horiuchi, Hiroshi Tsukamoto, Hiroaki Niiro, Terufumi Shimoda, Koichi Akashi, Toshihiko Yanase, Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A, MODERN RHEUMATOLOGY, 10.3109/14397595.2013.852838, 24, 1, 86-92, 2014.01.
17. Yuki H, Ueno S, Tatetsu H, Hiroaki Niiro, Tadafumi Iino, Endo S, Kawano Y, Komohara Y, Takeya M, Hata H, Okada S, Watanabe T, koichi akashi, Mitsuya H, Okuno Y, PU.1 is a potent tumor suppressor in classical Hodgkin lymphoma cells., Blood, 10.1182/blood-2012-05-431429, 121, 6, 962-970, 2013.03.
18. Ueda N, Hiroshi Tsukamoto, Hiroki Mitoma, Ayano M, Tanaka A, Ohta S, Inoue Y, Yojiro Arinobu, Hiroaki Niiro, koichi akashi, Takahiko Horiuchi, The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α., Inflamm Bowel Dis, 10.1097/MIB.0b013e318280b169, 19, 6, 1224-1231, 2013.05.
19. Atsushi Tanaka, Hiroshi Tsukamoto, Hiroaki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Inoue Yasushi, Yojiro Arinobu, Hiroaki Niiro, Takahiko Horiuchi, koichi akashi, Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.
, Arthritis Res Ther, 14, 6, R244, 2012.11.
20. Shigeru Iwata, Kunihiro Yamaoka, Hiroaki Niiro, Kazuhisa Nakano, Sheau-Pey Wang, koichi akashi, Yoshiya Tanaka, Amplification of toll-like receptor-mediated signaling through Syk in human B activation. , J Allergy Clin Immunol , 10.1016/j.jaci.2012.03.014., 129, 6, 1594-1601, 2012.06.
21. Niiro H, Jabbarzadeh-Tabrizi S, Kikushige Y, Shima T, Noda K, Ota SI, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, and Akashi K, CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells., Blood, 119, 10, 2263-2273, 2012.03.
22. Shimoda S, Harada K, Niiro H, Shirabe K, Taketomi A, Maehara Y, Tsuneyama K, Nakanuma Y, Leung P, Ansari AA, Gershwin ME, and Akashi K, Interaction between Toll-like receptors and natural iiller cells in the destruction of bile ducts in primary biliary cirrhosis., Hepatology, 53, 4, 1270-1281, 2011.04.
23. Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, and Akashi K, Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis: predominant reconstitution of Th1 CD4+ T cells., Rheumatology, 50, 5, 944-952, 2011.05.
24. Wakasaki T, Masuda M, Niiro H, Jabbarzadeh-Tabrizi S, Noda K, Taniyama T, Komune S, and Akashi K, A critical role of c-Cbl interacting protein of 85 kDa in the development and progression of head and neck squamous cell carcinomas via the Ras-ERK pathway., Neoplasia, 12, 10, 789-796, 2010.10.
25. Uchino A, Tsukamoto H, Nakashima H, Yoshizawa S, Furugo I, Mitoma H, Oryoji K, Shimoda T, Niiro H, Tada Y, Yano T, Nonaka T, Oishi R, Akashi K, and Horiuchi T, Tacrolimus is effective for lupus nephritis patients with persistent proteinuria, Clin Exp Rheumatol, 28, 1, 6-12, 2010.01.
26. Yoshimoto G, Miyamoto T, Jabbarzadeh-Tabrizi S, Iino T, Rocnik JL, Kikushige Y, Mori Y, Shima T, Iwasaki H, Takenaka K, Nagafuji K, Mizuno S-I, Niiro H, Gilliland GD, and Akashi K, FLT3-ITD upregulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation , Blood, 114, 24, 5034-5043, 2009.12.
27. Shimoda S, Harada K, Niiro H, Taketomi A, Maehara Y, Tsuneyama K, Kikuchi K, Nakanuma Y, Mackay IR, Gershwin EM, and Akashi K, CX3CL1 (FRACTALKINE): A SIGNPOST FOR BILIARY INFLAMMATION IN PRIMARY BILIARY CIRRHOSIS., Hepatology, 2009.09.
28. Ueno S, Tatetsu H, Hata H, Iino T, Niiro H, Akashi K, Tenen DG, Mitsuya H, and Okuno Y, PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL., Oncogene, 2009.09.
29. Mori Y, Iwasaki H, Kohno K, Yoshimoto G, Kikushige Y, Okeda A, Uike N, Niiro H, Takenaka K, Nagafuji K, Miyamoto T, Harada M, Takatsu K, Akashi K, Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor., J Exp Med, 206(1): 183-193, 2009.01.
30. Jabbarzadeh-Tabrizi S, Niiro H, Masui M, Yoshimoto G, Iino T, Kikushige Y, Wakasaki T, Baba E, Shimoda S, Miyamoto T, Hara T, Akashi , T cell leukemia/lymphoma 1 and Galectin-1 regulate survival/cell death pathways in human naïve and IgM+ memory B cells through altering balances in Bcl-2 family proteins., J. Immunol, 182(3): 1490-1499, 2009.02.
31. Koyama M, Hashimoto D, Aoyama K, Matsuoka K, Karube K, Niiro H, Harada M, Tanimoto M, Akashi K, and Teshima T, Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells. , Blood, 113(9): 2088-2095, 2009.02.