Life Science / Hygiene and public health

Life Science / Nephrology

QT Interval Prolongation and Dementia in a General Japanese Population: the Hisayama Study Reviewed

Mashima T, Oishi E, Honda T, Hata J, Minohara T, Ohara T, Nakao T, Kitazono T, Yamaura K, Ninomiya T.

J Atheroscler Thromb   2025.7

Global Effect of Cardiovascular Risk Factors on Lifetime Estimates Reviewed

Global Cardiovascular Risk Consortium; Magnussen C, Alegre-Diaz J, Al-Nasser LA, Amouyel P, Aviles-Santa L, Bakker SJL, Ballantyne CM, Bernabé-Ortiz A, Bobak M, Boffetta P, Brenner H, Brunström M, Can G, Carrillo-Larco RM, Checkley W, Dallongeville J, De Bacquer D, de Gaetano G, de Lemos JA, di Carluccio E, Dobson A, Donfrancesco C, Dörr M, d'Orsi E, Drygas W, Dullaart RPF, Engström G, Ferrario MM, Ferrières J, Figtree GA, Gaye B, Ghayour-Mobarhan M, Goldbourt U, Gonzalez C, Gossling A, Grassi G, Gupta PC, He J, Hodge AM, Hozawa A, Hveem K, Iacoviello L, Ikram MK, Inoue M, Irazola V, Jobe M, Jousilahti P, Kaleebu P, Kavousi M, Kee F, Khalili D, Klotsche J, Koenig W, Kontsevaya A, Kowlessur S, Kuri-Morales P, Kuulasmaa K, Kweon SS, Lackner KJ, Landmesser U, Leistner DM, Leiva Sisnieguez CE, Leong D, Lind L, Linneberg A, Lorenz T, Lyngbakken MN, Malekzadeh R, Malyutina S, Mathiesen EB, McElduff P, Melander O, Metspalu A, Miranda JJ, Moitry M, Mugisha J, Munzinger J, Nalini M, Nambi V, Nilsson PM, Ninomiya T, Omland T, Ong SK, Oppermann K, Pajak A, Palmieri L, Panagiotakos D, Park SK, Pednekar MS, Perianayagam A, Peters A, Poustchi H, Prabhakaran D, Prentice AM, Prescott E, Quyyumi A, Risérus U, Sakata S, Salazar M, et al.

N Engl J Med   393   125 - 138   2025.7

Differential brain volume between obese and underweight cognitively normal older adults with frailty in the JPSC-AD Reviewed

Ishizuka N, Akasaka H, Sato M, Sato Y, Hosokawa K, Takahashi J, Yonezawa H, Terayama Y, Ohara T, Honda T, Shibata M, Hata J, Tatewaki Y, Taki Y, Mikami T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T, Maeda T; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

Sci Rep   15   19702 - 0   2025.6

Secular Trends in the Prevalence of Total and Latent Prostate Cancer over Half a Century According to Consecutive Autopsy Cases in a Japanese community: The Hisayama Study Reviewed

Taira J, Kawatoko K, Takamatsu D, Shiota M, Ogata H, Hata J, Oishi E, Sakata S, Furuta Y, Shibata M, Ohara T, Oda Y, Eto M, Ninomiya T.

Eur Urol Open Sci   78   9 - 15   2025.6

Developing and Validating a New Atrial Fibrillation Risk Score Using Medical Examination Items in a Japanese Population　- The Suita Study Reviewed

Arafa A, Kato Y, Sakata S, Ninomiya T, Khairan P, Kawachi H, Nakao YM, Matsumoto C, Mizuno A, Kokubo Y.

Circ J   89   819 - 825   2025.5

Influence of chronic pain on regional brain volume reduction in a general older Japanese population: a longitudinal imaging analysis from the Hisayama Study Reviewed

Nakamura Y, Shibata M, Hirabayashi N, Nakazawa T, Furuta Y, Hata J, Hosoi M, Sudo N, Yamaura K, Ninomiya T.

Brain Commun   7   fcaf149 - fcaf149   2025.4

Association of sarcopenia with regional brain atrophy and white matter lesions in a general older population: the Hisayama Study Reviewed

Tajimi T, Hirabayashi N, Furuta Y, Nakazawa T, Honda T, Hata J, Ohara T, Shibata M, Kitazono T, Nakashima Y, Ninomiya T.

Geroscience   47   1187 - 1198   2025.2

The prevalence of chronic pain and its impact on activities of daily living disability and depressive symptoms according to multiple definitions in a Japanese population: the Hisayama study Reviewed

Shibata M, Hosoi M, Anno K, Hirabayashi N, Morisaki Y, Saito T, Sudo N, Ninomiya T.

Pain Rep   10   e1250 - e1250   2025.2

Green tea consumption and cerebral white matter lesions in community-dwelling older adults without dementia Reviewed

Shibata S, Noguchi-Shinohara M, Shima A, Ozaki T, Usui Y, Taki Y, Uchida K, Honda T, Hata J, Ohara T, Mikami T, Maeda T, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T, Ono K; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

NPJ Sci Food   9   2 - 2   2025.1

Association between hypothalamic Alzheimer's disease pathology and body mass index: The Hisayama study Reviewed

Yagita K, Honda H, Ohara T, Koyama S, Noguchi H, Oda Y, Yamasaki R, Isobe N, Ninomiya T.

Neuropathology   44   388 - 400   2024.12

Behavioral and psychological symptoms and brain volumes in community-dwelling older persons from the Nakayama Study Reviewed

Tachibana A, Iga JI, Ozaki T, Yoshino Y, Yamazaki K, Ochi S, Kawabe K, Horiuchi F, Yoshida T, Shimizu H, Mori T, Tatewaki Y, Taki Y, Ninomiya T, Ueno SI.

Sci Rep   14   26097 - 26097   2024.12

Association between dynapenic obesity and risk of cardiovascular disease: The Hisayama study Reviewed

Setoyama Y, Honda T, Tajimi T, Sakata S, Oishi E, Furuta Y, Shibata M, Hata J, Kitazono T, Nakashima Y, Ninomiya T.

J Cachexia Sarcopenia Muscle   15   2338 - 2348   2024.12

Skin carotenoid scores and metabolic syndrome in a general Japanese population: the Hisayama study Reviewed

Kimura Y, Hata J, Shibata M, Honda T, Sakata S, Furuta Y, Oishi E, Kitazono T, Ninomiya T.

Int J Obes (Lond)   48   1465 - 1471   2024.12

Novel method for classification of prion diseases by detecting PrP(res) signal patterns from formalin-fixed paraffin-embedded samples Reviewed

Koyama S, Yagita K, Hamasaki H, Noguchi H, Shijo M, Matsuzono K, Takase KI, Kai K, Aishima SI, Itoh K, Ninomiya T, Sasagasako N, Honda H.

Prion   18   40 - 53   2024.12

Associations between the Serum Triglyceride Level and Kidney Outcome in Patients with Chronic Kidney Disease: The Fukuoka Kidney disease Registry Study Reviewed

Seki M, Nakano T, Tanaka S, Kitamura H, Hiyamuta H, Ninomiya T, Tsuruya K, Kitazono T.

J Atheroscler Thromb   31   1556 - 1570   2024.11

Common protein-altering variant in GFAP is associated with white matter lesions in the older Japanese population Reviewed

Furuta Y, Akiyama M, Hirabayashi N, Honda T, Shibata M, Ohara T, Hata J, Terao C, Momozawa Y, Tatewaki Y, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; Japan Prospective Studies for Aging and Dementia (JPSC-AD) Study Group.

NPJ Genom Med   9   59 - 59   2024.11

Genetic Risk Stratification of Primary Open-Angle Glaucoma in Japanese Individuals Reviewed

Akiyama M, Tamiya G, Fujiwara K, Shiga Y, Yokoyama Y, Hashimoto K, Sato M, Sato K, Narita A, Hashimoto S, Ueda E, Furuta Y, Hata J, Miyake M, Ikeda HO, Suda K, Numa S, Mori Y, Morino K, Murakami Y, Shimokawa S, Nakamura S, Yawata N, Fujisawa K, Yamana S, Mori K, Ikeda Y, Miyata K, Mori K, Ogino K, Koyanagi Y, Kamatani Y; Biobank Japan Project; Ninomiya T, Sonoda KH, Nakazawa T; Japan Glaucoma Society Omics Group; Genomic Research Committee of the Japanese Ophthalmological Society.

Ophthalmology   131   1271 - 1280   2024.11

Vascular Calcification Is Accelerated by Hyponatremia and Low Osmolality Reviewed

Matsueda S, Yamada S, Torisu K, Kitamura H, Ninomiya T, Nakano T, Kitazono T.

Arterioscler Thromb Vasc Biol   44   1925 - 1943   2024.9

Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function Reviewed

Shima A, Noguchi-Shinohara M, Shibata S, Usui Y, Tatewaki Y, Thyreau B, Hata J, Ohara T, Honda T, Taki Y, Nakaji S, Maeda T, Mimura M, Nakashima K, Iga JI, Takebayashi M, Nishijo H, Ninomiya T, Ono K; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

NPJ Aging   10   39 - 39   2024.9

Association between Vascular Calcification and Intraplaque Hemorrhage in Coronary Atherosclerosis from Autopsy: The Hisayama Study Reviewed

Nakano T, Kitamura H, Hata J, Maki K, Oda Y, Kitazono T, Ninomiya T.

J Atheroscler Thromb   31   1225 - 1237   2024.8

Association between corneal hysteresis and glaucoma in a Japanese population: the Hisayama Study Reviewed

Fujiwara K, Ueda E, Hata J, Nakano S, Hashimoto S, Nakamura S, Murakami Y, Kubota T, Yoshitomi T, Ninomiya T, Sonoda KH.

Br J Ophthalmol   108   1204 - 1209   2024.8

Risks of Dementia in a General Japanese Older Population With Preserved Ratio Impaired Spirometry: The Hisayama Study Reviewed

Kawatoko K, Washio Y, Ohara T, Fukuyama S, Honda T, Hata J, Nakazawa T, Kan-O K, Inoue H, Matsumoto K, Nakao T, Kitazono T, Okamoto I, Ninomiya T.

J Epidemiol   34   331 - 339   2024.7

Day-to-day home blood pressure variability and risk of atrial fibrillation in a general Japanese population: the Hisayama Study Reviewed

Maezono A, Sakata S, Hata J, Oishi E, Furuta Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T.

Eur J Prev Cardiol   31   1115 - 1122   2024.7

Plasma biomarkers for predicting the development of dementia in a community-dwelling older Japanese population Reviewed

Ohara T, Tatebe H, Hata J, Honda T, Shibata M, Matsuura S, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Tokuda T, Ninomiya T; JPSC‐AD (Japan Prospective Studies Collaboration for Aging and Dementia) study group.

Psychiatry Clin Neurosci   78   362 - 371   2024.6

Association between masticatory function, frailty, and functional disability: an observational study Reviewed

Furuhashi H, Honda T, Furuta Y, Tomooka S, Tajimi T, Kimura Y, Yoshida D, Ninomiya T.

BMC Geriatr   24   538 - 538   2024.6

Autonomic nervous system function assessed by heart rate variability and the presence of symptoms affecting activities of daily living in community-dwelling residents with chronic pain: The Hisayama Study Reviewed

Nakamura Y, Shibata M, Morisaki Y, Hirabayashi N, Higashioka M, Hata J, Hosoi M, Sudo N, Yamaura K, Ninomiya T.

Eur J Pain   28   831 - 844   2024.5

Association between retinopathy and risk of dementia in a general Japanese population: the Hisayama Study Reviewed

Nakamura S, Ueda E, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakazawa T, Nakao T, Kitazono T, Sonoda KH, Ninomiya T.

Sci Rep   14   12017 - 12017   2024.5

Association Between Serum NT-proBNP and Gray Matter Atrophy Patterns in an Older Japanese Population: The Hisayama Study Reviewed

Hirabayashi N, Hata J, Furuta Y, Nakazawa T, Ohara T, Shibata M, Yamashita F, Kitazono T, Sudo N, Ninomiya T.

J Gerontol A Biol Sci Med Sci   79   glae075 - glae075   2024.5

Brain atrophy in normal older adult links tooth loss and diet changes to future cognitive decline Reviewed

Nakamura H, Noguchi-Shinohara M, Ishimiya-Jokaji M, Kobayashi Y, Isa M, Ide K, Kawano T, Kawashiri S, Uchida K, Tatewaki Y, Taki Y, Ohara T, Ninomiya T, Ono K.

NPJ Aging   10   20 - 20   2024.3

Descriptive epidemiology of muscle-strengthening activities in Japanese middle-aged and older adults: the Hisayama Study Reviewed

Honda T, Hata J, Shibata M, Sakata S, Furuta Y, Oishi E, Kitazono T, Ninomiya T.

BMJ Public Health   2   e000186 - e000186   2024.3

Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD) Reviewed

Tachibana A, Iga JI, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group.

Sci Rep   14   7374 - 7374   2024.3

Longitudinal association of sedentary time with diabetes mellitus and markers of glucose metabolism in middle-aged and older adults: The Hisayama Study Reviewed

Tsuda S, Honda T, Higashioka M, Hata J, Nakano T, Kitazono T, Ninomiya T.

J Diabetes Investig   15   245 - 246   2024.2

Serum Lipopolysaccharide-binding Protein Levels and the Incidence of Metabolic Syndrome in a General Japanese Population: the Hisayama Study Reviewed

Tomooka S, Oishi E, Asada M, Sakata S, Hata J, Chen S, Honda T, Suzuki K, Watanabe H, Murayama N, Wada N, Kitazono T, Ninomiya T.

J Epidemiol   34   1 - 7   2024.1

Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies Reviewed

Laguzzi F, Åkesson A, Marklund M, Qian F, Gigante B, Bartz TM, Bassett JK, Birukov A, Campos H, Hirakawa Y, Imamura F, Jäger S, Lankinen M, Murphy RA, Senn M, Tanaka T, Tintle N, Virtanen JK, Yamagishi K, Allison M, Brouwer IA, De Faire U, Eiriksdottir G, Ferrucci L, Forouhi NG, Geleijnse JM, Hodge AM, Kimura H, Laakso M, Risérus U, van Westing AC, Bandinelli S, Baylin A, Giles GG, Gudnason V, Iso H, Lemaitre RN, Ninomiya T, Post WS, Psaty BM, Salonen JT, Schulze MB, Tsai MY, Uusitupa M, Wareham NJ, Oh SW, Wood AC, Harris WS, Siscovick D, Mozaffarian D, Leander K; Fatty Acids and Outcomes Research Consortium (FORCE).

Circulation   149   305 - 316   2024.1

Late-Life High Blood Pressure and Enlarged Perivascular Spaces in the Putaminal Regions of Community-Dwelling Japanese Older Persons Reviewed

Tachibana A, Iga JI, Tatewaki Y, Thyreau B, Chen H, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group.

J Geriatr Psychiatry Neurol   37   61 - 72   2024.1

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality Reviewed

Global Cardiovascular Risk Consortium; Magnussen C, Ojeda FM, Leong DP, Alegre-Diaz J, Amouyel P, Aviles-Santa L, De Bacquer D, Ballantyne CM, Bernabé-Ortiz A, Bobak M, Brenner H, Carrillo-Larco RM, de Lemos J, Dobson A, Dörr M, Donfrancesco C, Drygas W, Dullaart RP, Engström G, Ferrario MM, Ferrières J, de Gaetano G, Goldbourt U, Gonzalez C, Grassi G, Hodge AM, Hveem K, Iacoviello L, Ikram MK, Irazola V, Jobe M, Jousilahti P, Kaleebu P, Kavousi M, Kee F, Khalili D, Koenig W, Kontsevaya A, Kuulasmaa K, Lackner KJ, Leistner DM, Lind L, Linneberg A, Lorenz T, Lyngbakken MN, Malekzadeh R, Malyutina S, Mathiesen EB, Melander O, Metspalu A, Miranda JJ, Moitry M, Mugisha J, Nalini M, Nambi V, Ninomiya T, Oppermann K, d'Orsi E, Pająk A, Palmieri L, Panagiotakos D, Perianayagam A, Peters A, Poustchi H, Prentice AM, Prescott E, Risérus U, Salomaa V, Sans S, Sakata S, Schöttker B, Schutte AE, Sepanlou SG, Sharma SK, Shaw JE, Simons LA, Söderberg S, Tamosiunas A, Thorand B, Tunstall-Pedoe H, Twerenbold R, Vanuzzo D, Veronesi G, Waibel J, Wannamethee SG, Watanabe M, Wild PS, Yao Y, Zeng Y, Ziegler A, Blankenberg S.

N Engl J Med   389   1273 - 1285   2023.12

Database profile of the Fukuoka-City Information Platform for Community-based Integrated Care Reviewed

Honda T, Furuhashi H, Furuta Y, Tomooka S, Tajimi T, Nagasawa F, Oishi E, Kimura Y, Yoshida D, Ninomiya T.

Ann Clin Epidemiol   6   5 - 11   2023.12

Development and Validation of a Risk Prediction Model for Atherosclerotic Cardiovascular Disease in Japanese Adults: The Hisayama Study Reviewed

Honda T, Chen S, Hata J, Yoshida D, Hirakawa Y, Furuta Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

J Atheroscler Thromb   30   1966 - 1967   2023.12

Inadequate care and excessive overprotection during childhood are associated with the presence of diabetes mellitus in adulthood in a general Japanese population: a cross-sectional analysis from the Hisayama Study Reviewed

Shibata M, Hosoi M, Anno K, Hirabayashi N, Hirakawa Y, Kawata H, Iwaki R, Sawamoto R, Sudo N, Ninomiya T.

BMC Endocr Disord   23   222 - 222   2023.12

Gender and age influence the association between gait speed and mild cognitive impairment in community-dwelling Japanese older adults: from the Japan Prospective Studies Collaboration for Ageing and Dementia (JPSC-AD) Reviewed

Bun S, Suzuki K, Niimura H, Shikimoto R, Kida H, Shibata M, Honda T, Ohara T, Hata J, Nakaji S, Maeda T, Ono K, Nakashima K, Iga JI, Takebayashi M, Ninomiya T, Mimura M; JPSC-AD Study Group.

Psychogeriatrics   23   918 - 929   2023.11

n-6 fatty acid biomarkers and incident atrial fibrillation: an individual participant-level pooled analysis of 11 international prospective studies Reviewed

Garg PK, Guan W, Nomura S, Weir NL, Tintle N, Virtanen JK, Hirakawa Y, Qian F, Sun Q, Rimm E, Lemaitre RN, Jensen PN, Heckbert SR, Imamura F, Steur M, Leander K, Laguzzi F, Voortman T, Ninomiya T, Mozaffarian D, Harris WS, Siscovick DS, Tsai MY; Fatty Acids and Outcomes Research Consortium (FORCE).

Am J Clin Nutr   118   921 - 929   2023.11

Association Between Frequency of Social Contact and Brain Atrophy in Community-Dwelling Older People Without Dementia: The JPSC-AD Study Reviewed

Hirabayashi N, Honda T, Hata J, Furuta Y, Shibata M, Ohara T, Tatewaki Y, Taki Y, Nakaji S, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; as the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study.

Neurology   101   e1108 - e1117   2023.9

Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation Reviewed

Qian F, Tintle N, Jensen PN, Lemaitre RN, Imamura F, Feldreich TR, Nomura SO, Guan W, Laguzzi F, Kim E, Virtanen JK, Steur M, Bork CS, Hirakawa Y, O'Donoghue ML, Sala-Vila A, Ardisson Korat AV, Sun Q, Rimm EB, Psaty BM, Heckbert SR, Forouhi NG, Wareham NJ, Marklund M, Risérus U, Lind L, Ärnlöv J, Garg P, Tsai MY, Pankow J, Misialek JR, Gigante B, Leander K, Pester JA, Albert CM, Kavousi M, Ikram A, Voortman T, Schmidt EB, Ninomiya T, Morrow DA, Bayés-Genís A, O'Keefe JH, Ong KL, Wu JHY, Mozaffarian D, Harris WS, Siscovick DS; Fatty Acids and Outcomes Research Consortium (FORCE).

J Am Coll Cardiol   82   336 - 349   2023.7

Changes in the Eicosapentaenoic Acid to Arachidonic Acid Ratio in Serum over 10 Years in a Japanese Community: The Hisayama Study Reviewed

Honda T, Chen S, Hata J, Shibata M, Furuta Y, Oishi E, Sakata S, Kitazono T, Ninomiya T.

J Atheroscler Thromb   30   589 - 600   2023.6

Association Between Choroidal Thickness and Myopic Maculopathy in a Japanese Population: The Hisayama Study Reviewed

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Honda T, Nakamura S, Hata J, Ninomiya T, Sonoda KH.

Ophthalmol Sci   3   100350 - 100350   2023.6

Association of white matter lesions and brain atrophy with the development of dementia in a community: the Hisayama Study Reviewed

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T.

Psychiatry Clin Neurosci   77   330 - 337   2023.6

Serum Mac-2 Binding Protein Glycosylation Isomer Concentrations Are Associated With Incidence of Type 2 Diabetes Reviewed

Higashioka M, Hirakawa Y, Hata J, Honda T, Sakata S, Shibata M, Kitazono T, Osawa H, Ninomiya T.

J Clin Endocrinol Metab   108   e425 - e433   2023.6

Family dysfunction is associated with chronic pain in a community-dwelling Japanese population: The Hisayama study Reviewed

Saito T, Shibata M, Hirabayashi N, Honda T, Morisaki Y, Anno K, Sudo N, Hosoi M, Ninomiya T.

Eur J Pain   27   518 - 529   2023.4

Secular trends in the prevalence, incidence, and progression of diabetic retinopathy: the Hisayama Study Reviewed

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Nakamura S, Hirakawa Y, Higashioka M, Hata J, Ninomiya T, Sonoda KH.

Graefes Arch Clin Exp Ophthalmol   261   641 - 649   2023.3

Sex differences in risk factors for end-stage kidney disease and death in type 2 diabetes: A retrospective cohort study Reviewed

Oshima M, Iwata Y, Toyama T, Kitajima S, Hara A, Sakai N, Shimizu M, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T.

J Diabetes   15   246 - 254   2023.3

Association of gait speed with regional brain volumes and risk of dementia in older Japanese: The Hisayama study Reviewed

Tajimi T, Furuta Y, Hirabayashi N, Honda T, Hata J, Ohara T, Shibata M, Nakao T, Kitazono T, Nakashima Y, Ninomiya T.

Arch Gerontol Geriatr   106   104883 - 104883   2023.3

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals Reviewed

Akiyama M, Sakaue S, Takahashi A, Ishigaki K, Hirata M, Matsuda K, Momozawa Y, Okada Y, Ninomiya T; Biobank Japan project; Terao C, Murakami Y, Kubo M, Kamatani Y.

Commun Biol   6   143 - 143   2023.2

The effect of the Kasuya CKD network on prevention of the progression of chronic kidney disease: successful collaboration of a public health service, primary care physicians and nephrologists-community based cohort study Reviewed

Katafuchi R, Tanaka S, Matsuo T, Tamai O, Yoshimine K, Yano K, Ueno K, Shimohashi N, Ninomiya T; Kasuya Chronic Kidney Disease Committee.

Clin Exp Nephrol   27   32 - 43   2023.1

Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts Reviewed

Ong KL, Marklund M, Huang L, Rye KA, Hui N, Pan XF, Rebholz CM, Kim H, Steffen LM, van Westing AC, Geleijnse JM, Hoogeveen EK, Chen YY, Chien KL, Fretts AM, Lemaitre RN, Imamura F, Forouhi NG, Wareham NJ, Birukov A, Jäger S, Kuxhaus O, Schulze MB, de Mello VD, Tuomilehto J, Uusitupa M, Lindström J, Tintle N, Harris WS, Yamasaki K, Hirakawa Y, Ninomiya T, Tanaka T, Ferrucci L, Bandinelli S, Virtanen JK, Voutilainen A, Jayasena T, Thalamuthu A, Poljak A, Bustamante S, Sachdev PS, Senn MK 2nd, Rich SS, Tsai MY, Wood AC, Laakso M, Lankinen M, Yang X, Sun L, Li H, Lin X, Nowak C, Ärnlöv J, Risérus U, Lind L, Le Goff M, Samieri C, Helmer C, Qian F, Micha R, Tin A, Köttgen A, de Boer IH, Siscovick DS, Mozaffarian D, Wu JH.

BMJ   15.833333333333334   e072909 - e072909   2023.1

Long-Term Trends in The 5-Year Risk of Recurrent Stroke over A Half Century in A Japanese Community: The Hisayama Study Reviewed

Nakanishi Y, Furuta Y, Hata J, Yubi T, Oishi E, Sakata S, Hirakawa Y, Wakisaka Y, Ago T, Kitazono T, Ninomiya T.

J Atheroscler Thromb   29   1759 - 1773   2022.12

CKD, Brain Atrophy, and White Matter Lesion Volume: The Japan Prospective Studies Collaboration for Aging and Dementia Reviewed

Maki K, Ohara T, Hata J, Shibata M, Hirabayashi N, Honda T, Sakata S, Furuta Y, Akiyama M, Yamasaki K, Tatewaki Y, Taki Y, Kitazono T, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Iga JI, Takebayashi M, Ninomiya T; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

Kidney Med   5   100593 - 100593   2022.12

Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries Reviewed

Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, et al.

Nature   612   E7 - E7   2022.12

Day-to-Day Blood Pressure Variability and Risk of Incident Chronic Kidney Disease in a General Japanese Population Reviewed

Sasaki T, Sakata S, Oishi E, Furuta Y, Honda T, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T.

J Am Heart Assoc   11   e027173 - e027173   2022.12

Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype Reviewed

Yagita K, Noguchi H, Koyama S, Hamasaki H, Komori T, Aishima S, Kosaka T, Ueda M, Komohara Y, Watanabe A, Sasagasako N, Ninomiya T, Oda Y, Honda H.

J Neuropathol Exp Neurol   81   900 - 909   2022.12

Active commuting, commuting modes and the risk of diabetes: 14-year follow-up data from the Hisayama study Reviewed

Honda T, Hirakawa Y, Hata J, Chen S, Shibata M, Sakata S, Furuta Y, Higashioka M, Oishi E, Kitazono T, Ninomiya T.

J Diabetes Investig   13   1677 - 1684   2022.12

Association between chronic low back pain and regional brain atrophy in a Japanese older population: the Hisayama Study Reviewed

Asada M, Shibata M, Hirabayashi N, Ohara T, Furuta Y, Nakazawa T, Honda T, Hata J, Hosoi M, Sudo N, Yamaura K, Ninomiya T.

Pain   163   2185 - 2193   2022.11

Prevalence of Glaucoma and Its Systemic Risk Factors in a General Japanese Population: The Hisayama Study Reviewed

Fujiwara K, Yasuda M, Hata J, Nakano S, Hashimoto S, Ueda E, Nakamura S, Murakami Y, Nakamuro T, Iwase A, Araie M, Tawara A, Kubota T, Yoshitomi T, Ninomiya T, Sonoda KH.

Transl Vis Sci Technol   11   11 - 11   2022.11

Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses Reviewed

Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK, Song RJ, Burgess S, Posner DC, Mosconi K, Robinson-Cohen C, Mason AM, Bolton TR, Tao R, Allara E, Schubert P, Chen L, Staley JR, Staplin N, Altay S, Amiano P, Arndt V, Ärnlöv J, Barr ELM, Björkelund C, Boer JMA, Brenner H, Casiglia E, Chiodini P, Cooper JA, Coresh J, Cushman M, Dankner R, Davidson KW, de Jongh RT, Donfrancesco C, Engström G, Freisling H, de la Cámara AG, Gudnason V, Hankey GJ, Hansson PO, Heath AK, Hoorn EJ, Imano H, Jassal SK, Kaaks R, Katzke V, Kauhanen J, Kiechl S, Koenig W, Kronmal RA, Kyrø C, Lawlor DA, Ljungberg B, MacDonald C, Masala G, Meisinger C, Melander O, Moreno Iribas C, Ninomiya T, Nitsch D, Nordestgaard BG, Onland-Moret C, Palmieri L, Petrova D, Garcia JRQ, Rosengren A, Sacerdote C, Sakurai M, Santiuste C, Schulze MB, Sieri S, Sundström J, Tikhonoff V, Tjønneland A, Tong T, Tumino R, Tzoulaki I, van der Schouw YT, Monique Verschuren WM, Völzke H, Wallace RB, Wannamethee SG, Weiderpass E, Willeit P, Woodward M, Yamagishi K, Zamora-Ros R, Akwo EA, Pyarajan S, Gagnon DR, Tsao PS, Muralidhar S, Edwards TL, Damrauer SM, Joseph J, Pennells L, Wilson PWF, Harrison S, et al.

Circulation   146   1507 - 1517   2022.11

Stroke genetics informs drug discovery and risk prediction across ancestries Reviewed

Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, et al.

Nature   611   115 - 123   2022.11

Altruistic Social Activity, Depressive Symptoms, and Brain Regional Gray Matter Volume: Voxel-Based Morphometry Analysis From 8,695 Old Adults Reviewed

Liu Y, Zhang Y, Thyreau B, Tatewaki Y, Matsudaira I, Takano Y, Hirabayashi N, Furuta Y, Hata J, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group.

J Gerontol A Biol Sci Med Sci   77   1789 - 1797   2022.9

Secular trends in the prevalence of dementia based on a community-based complete enumeration in Japan: the Nakayama Study Reviewed

Shimizu H, Mori T, Yoshida T, Tachibana A, Ozaki T, Yoshino Y, Ochi S, Sonobe N, Matsumoto T, Komori K, Iga JI, Ninomiya T, Ueno SI, Ikeda M.

Psychogeriatrics   22   631 - 641   2022.9

Risks of Mortality and Airflow Limitation in Japanese Individuals with Preserved Ratio Impaired Spirometry Reviewed

Washio Y, Sakata S, Fukuyama S, Honda T, Kan-O K, Shibata M, Hata J, Inoue H, Kitazono T, Matsumoto K, Ninomiya T.

Am J Respir Crit Care Med   206   563 - 572   2022.9

Higher-resolution quantification of white matter hypointensities by large-scale transfer learning from 2D images on the JPSC-AD cohort Reviewed

Thyreau B, Tatewaki Y, Chen L, Takano Y, Hirabayashi N, Furuta Y, Hata J, Nakaji S, Maeda T, Noguchi-Shinohara M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ninomiya T, Taki Y; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Study Group.

Hum Brain Mapp   43   3998 - 4012   2022.9

Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study Reviewed

Noguchi-Shinohara M, Ono K, Yuki-Nozaki S, Iwasa K, Yokogawa M, Komai K, Thyreau B, Tatewaki Y, Taki Y, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M.

Sci Rep   12   12129 - 12129   2022.8

Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community Reviewed

Mihara A, Ohara T, Hata J, Chen S, Honda T, Tamrakar S, Isa A, Wang D, Shimizu K, Katakura Y, Yonemoto K, Nakao T, Kitazono T, Ninomiya T.

Sci Rep   12   12427 - 12427   2022.7

Association Between Diabetes and Gray Matter Atrophy Patterns in a General Older Japanese Population: The Hisayama Study Reviewed

Hirabayashi N, Hata J, Furuta Y, Ohara T, Shibata M, Hirakawa Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Ninomiya T.

Diabetes Care   45   1364 - 1371   2022.6

Baseline periodontal status and modifiable risk factors are associated with tooth loss over a 10-year period: Estimates of population attributable risk in a Japanese community Reviewed

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Shimazaki Y, Hata J, Ninomiya T, Yamashita Y.

J Periodontol   93   526 - 536   2022.4

Association of Inner Retinal Thickness with Prevalent Dementia and Brain Atrophy in a General Older Population: The Hisayama Study Reviewed

Ueda E, Hirabayashi N, Ohara T, Hata J, Honda T, Fujiwara K, Furuta Y, Shibata M, Hashimoto S, Nakamura S, Nakazawa T, Nakao T, Kitazono T, Ninomiya T, Sonoda KH.

Ophthalmol Sci   2   100157 - 100157   2022.4

Yogurt product intake and reduction of tooth loss risk in a Japanese community Reviewed

Ma J, Furuta M, Uchida K, Takeshita T, Kageyama S, Asakawa M, Takeuchi K, Suma S, Sakata S, Hata J, Sohn W, Ninomiya T, Yamashita Y.

J Clin Periodontol   49   345 - 352   2022.4

Association of daily sleep duration with the incident dementia by serum soluble TREM2 in a community Reviewed

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Kitazono T, Nakao T, Satoh-Asahara N, Ninomiya T.

J Am Geriatr Soc   70   1147 - 1156   2022.4

Development and Validation of a Risk Prediction Model for Atherosclerotic Cardiovascular Disease in Japanese Adults: The Hisayama Study Reviewed

Honda T, Chen S, Hata J, Yoshida D, Hirakawa Y, Furuta Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

J Atheroscler Thromb   29   345 - 361   2022.3

Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama study Reviewed

Kimura Y, Yoshida D, Ohara T, Hata J, Honda T, Hirakawa Y, Shibata M, Oishi E, Sakata S, Furuta Y, Chen S, Uchida K, Nakao T, Kitazono T, Ninomiya T.

BMC Geriatr   22   257 - 257   2022.3

Multiple-region grey matter atrophy as a predictor for the development of dementia in a community: the Hisayama Study Reviewed

Nakazawa T, Ohara T, Hirabayashi N, Furuta Y, Hata J, Shibata M, Honda T, Kitazono T, Nakao T, Ninomiya T.

J Neurol Neurosurg Psychiatry   93   263 - 271   2022.3

Changes in Body Weight and Concurrent Changes in Cardiovascular Risk Profiles in Community Residents in Japan: the Hisayama Study Reviewed

Honda T, Ishida Y, Oda M, Noguchi K, Chen S, Sakata S, Oishi E, Furuta Y, Yoshida D, Hirakawa Y, Hata J, Kitazono T, Ninomiya T.

J Atheroscler Thromb   29   252 - 267   2022.2

Concurrent cardiac transthyretin and brain β amyloid accumulation among the older adults: The Hisayama study Reviewed

Hamasaki H, Shijo M, Nakamura A, Honda H, Yamada Y, Oda Y, Ohara T, Ninomiya T, Iwaki T.

Brain Pathol   32   e13014 - e13014   2022.1

Serum Uric Acid Levels and Nephrosclerosis in a Population-Based Autopsy Study: The Hisayama Study Reviewed

Maki K, Hata J, Sakata S, Oishi E, Furuta Y, Nakano T, Oda Y, Kitazono T, Ninomiya T.

Am J Nephrol   53   69 - 77   2022.1

Prevalence of chronic kidney disease in Asia: a systematic review and analysis Reviewed

Liyanage T, Toyama T, Hockham C, Ninomiya T, Perkovic V, Woodward M, Fukagawa M, Matsushita K, Praditpornsilpa K, Hooi LS, Iseki K, Lin MY, Stirnadel-Farrant HA, Jha V, Jun M.

BMJ Glob Health   7   e007525 - e007525   2022.1

A Comparative Study of Site-Specific Distribution of Aging-Related Tau Astrogliopathy and Its Risk Factors Between Alzheimer Disease and Cognitive Healthy Brains: The Hisayama Study Reviewed

Yagita K, Honda H, Ohara T, Hamasaki H, Koyama S, Noguchi H, Mihara A, Nakazawa T, Hata J, Ninomiya T, Iwaki T.

J Neuropathol Exp Neurol   81   106 - 116   2022.1

Diabetes Mellitus, Elevated Hemoglobin A1c, and Glycated Albumin Are Associated with the Presence of All-Cause Dementia and Alzheimer's Disease: The JPSC-AD Study Reviewed

Noguchi-Shinohara M, Yuki-Nozaki S, Abe C, Mori A, Horimoto M, Yokogawa M, Ishida N, Suga Y, Ishizaki J, Ishimiya M, Nakamura H, Komai K, Nakamura H, Shibata M, Ohara T, Hata J, Ninomiya T, Yamada M; Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group.

J Alzheimers Dis   85   235 - e020760   2022.1

Emotional Loneliness Is Associated With a Risk of Dementia in a General Japanese Older Population: The Hisayama Study Reviewed

Shibata M, Ohara T, Hosoi M, Hata J, Yoshida D, Hirabayashi N, Morisaki Y, Nakazawa T, Mihara A, Nagata T, Oishi E, Anno K, Sudo N, Ninomiya T.

J Gerontol B Psychol Sci Soc Sci   76   1756 - 1766   2021.12

Prediction of Lifetime Risk of Cardiovascular Disease Deaths Stratified by Sex in the Japanese Population Reviewed

Imai Y, Mizuno Tanaka S, Satoh M, Hirata T, Murakami Y, Miura K, Waki T, Hirata A, Sairenchi T, Irie F, Sata M, Ninomiya T, Ohkubo T, Ishikawa S, Miyamoto Y, Ohnishi H, Saitoh S, Tamakoshi A, Yamada M, Kiyama M, Iso H, Sakata K, Nakagawa H, Okayama A, Ueshima H, Okamura T; Evidence for Cardiovascular Prevention From Observational Cohorts in Japan (EPOCH‐Japan) Research Group *.

J Am Heart Assoc   10   e021753 - e021753   2021.12

Risk Classification for Metabolic Syndrome and the Incidence of Cardiovascular Disease in Japan With Low Prevalence of Obesity: A Pooled Analysis of 10 Prospective Cohort Studies Reviewed

Iso H, Cui R, Takamoto I, Kiyama M, Saito I, Okamura T, Miyamoto Y, Higashiyama A, Kiyohara Y, Ninomiya T, Yamada M, Nakagawa H, Sakurai M, Shimabukuro M, Higa M, Shimamoto K, Saito S, Daimon M, Kayama T, Noda M, Ito S, Yokote K, Ito C, Nakao K, Yamauchi T, Kadowaki T.

J Am Heart Assoc   10   e020760 - e020760   2021.12

Midlife and late-life diabetes and sarcopenia in a general older Japanese population: The Hisayama Study Reviewed

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Chen S, Kitazono T, Nakashima Y, Ninomiya T.

J Diabetes Investig   12   1899 - 1907   2021.12

Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution Reviewed

Tateishi Y, Yamada Y, Katsuki M, Nagata T, Yamamoto H, Kohashi K, Koga Y, Hashisako M, Kiyozawa D, Mori T, Kuboyama Y, Kakinokizono A, Miyazaki Y, Yamaguchi A, Tsutsui H, Ninomiya T, Naiki H, Oda Y.

Pathol Res Pract   227   153635 - 153635   2021.11

Serum NT-proBNP levels and histopathological myocardial fibrosis in autopsied cases from a Japanese community: The Hisayama Study Reviewed

Sasaki T, Izumaru K, Hata J, Sakata S, Oishi E, Nagata T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T.

J Cardiol   78   237 - 243   2021.9

Pathologic Diabetic Nephropathy in Autopsied Diabetic Cases With Normoalbuminuria From a Japanese Community-Based Study Reviewed

Sasaki T, Nakagawa K, Hata J, Hirakawa Y, Shibata M, Nakano T, Tsuboi N, Oda Y, Kitazono T, Yokoo T, Ninomiya T.

Kidney Int Rep   6   3035 - 3044   2021.9

Development of a risk prediction model for incident hypertension in Japanese individuals: the Hisayama Study Reviewed

Oishi E, Hata J, Honda T, Sakata S, Chen S, Hirakawa Y, Yoshida D, Shibata M, Ohara T, Furuta Y, Kitazono T, Ninomiya T.

Hypertens Res   44   1221 - 1229   2021.9

Comparison of the contributions of impaired beta cell function and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study Reviewed

Yoshinari M, Hirakawa Y, Hata J, Higashioka M, Honda T, Yoshida D, Mukai N, Nakamura U, Kitazono T, Ninomiya T.

Diabetologia   64   1775 - 1784   2021.8

10-year trend of tooth loss and associated factors in a Japanese population-based longitudinal study Reviewed

Furuta M, Takeuchi K, Takeshita T, Shibata Y, Suma S, Kageyama S, Asakawa M, Hata J, Yoshida D, Shimazaki Y, Ninomiya T, Yamashita Y.

BMJ Open   11   e048114 - e048114   2021.8

Serum High-Sensitivity C-Reactive Protein Levels and the Development of Atrial Fibrillation in a General Japanese Population　- The Hisayama Study Reviewed

Yoshikawa T, Hata J, Sakata S, Nagata T, Hirakawa Y, Hirooka Y, Tsutsui H, Kitazono T, Ninomiya T.

Circ J   85   1365 - 1372   2021.7

Development of a dementia prediction model for primary care: The Hisayama Study Reviewed

Honda T, Ohara T, Yoshida D, Shibata M, Ishida Y, Furuta Y, Oishi E, Hirakawa Y, Sakata S, Hata J, Nakao T, Ninomiya T.

Alzheimers Dement (Amst)   13   e12221 - e12221   2021.7

Risk Prediction Model for Incident Atrial Fibrillation in a General Japanese Population　- The Hisayama Study Reviewed

Hata J, Nagata T, Sakata S, Oishi E, Furuta Y, Hirakawa Y, Honda T, Yoshida D, Kitazono T, Ninomiya T.

Circ J   85   1373 - 1382   2021.7

Cohort Profile: The Ganka-Ekigaku Network (GEN), a Network of Japanese Ophthalmological Epidemiology Studies Reviewed

Sasaki M, Miyake M, Fujiwara K, Nanba H, Akiyama M, Yanagi Y, Harada S, Tabara Y, Yasuda M, Yamashita H, Kayama T, Tsubota K, Matsuda F, Hashimoto S, Ueda E, Ninomiya T, Takebayashi T, Tsujikawa A, Sonoda KH, Kawasaki R.

Ophthalmic Epidemiol   28   237 - 243   2021.6

Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes Reviewed

Oshima M, Toyama T, Hara A, Shimizu M, Kitajima S, Iwata Y, Sakai N, Furuichi K, Haneda M, Babazono T, Yokoyama H, Iseki K, Araki SI, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Makino H, Wada T.

BMJ Open Diabetes Res Care   9   e002311 - e002311   2021.6

Prevalence and Mortality of Sarcopenia in a Community-dwelling Older Japanese Population: The Hisayama Study Reviewed

Nakamura K, Yoshida D, Honda T, Hata J, Shibata M, Hirakawa Y, Furuta Y, Kishimoto H, Ohara T, Kitazono T, Nakashima Y, Ninomiya T.

J Epidemiol   31   320 - 327   2021.5

Airflow limitation and tongue microbiota in community-dwelling elderly individuals Reviewed

Takeshita T, Matsumoto K, Furuta M, Fukuyama S, Takeuchi K, Ogata H, Asakawa M, Kageyama S, Hata J, Ninomiya T, Inoue H, Yamashita Y.

ERJ Open Res   7   616 - 2020   2021.5

n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies Reviewed

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q; Fatty Acids and Outcomes Research Consortium (FORCE).

Diabetes Care   44   1133 - 1142   2021.5

Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: The Hisayama Study Reviewed

Ohara T, Yoshida D, Hata J, Shibata M, Honda T, Furuta Y, Hirabayashi N, Kitazono T, Nakao T, Ninomiya T.

Psychiatry Clin Neurosci   75   182 - 184   2021.5

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: The Hisayama Study Reviewed

Kimura Y, Yoshida D, Hirakawa Y, Hata J, Honda T, Shibata M, Sakata S, Uchida K, Kitazono T, Ninomiya T.

J Diabetes Investig   12   527 - 536   2021.4

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies Reviewed

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Risérus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D; Fatty Acids and Outcomes Research Consortium (FORCE).

Nat Commun   12   2329 - 2329   2021.4

Urinary N-terminal pro-B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study Reviewed

Yamasaki K, Hata J, Ide T, Nagata T, Sakata S, Yoshida D, Honda T, Hirakawa Y, Nakano T, Kitazono T, Tsutsui H, Ninomiya T.

Environ Health Prev Med   26   47 - 47   2021.4

High Serum Folate Concentrations Are Associated with Decreased Risk of Mortality among Japanese Adults Reviewed

Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T.

J Nutr   151   657 - 665   2021.3

Risk prediction for new-onset atrial fibrillation using the Minnesota code electrocardiography classification system Reviewed

Igarashi Y, Nochioka K, Sakata Y, Tamai T, Ohkouchi S, Irokawa T, Ogawa H, Hayashi H, Fujihashi T, Yamanaka S, Shiroto T, Miyata S, Hata J, Yamada S, Ninomiya T, Yasuda S, Kurosawa H, Shimokawa H.

Int J Cardiol Heart Vasc   34   100762 - 100762   2021.3

Randomized trial of an intensified, multifactorial intervention in patients with advanced-stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan) Reviewed

Shikata K, Haneda M, Ninomiya T, Koya D, Suzuki Y, Suzuki D, Ishida H, Akai H, Tomino Y, Uzu T, Nishimura M, Maeda S, Ogawa D, Miyamoto S, Makino H; Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan) collaborative group.

J Diabetes Investig   12   207 - 216   2021.2

PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis Reviewed

Yoshimura M, Honda H, Sasagasako N, Mori S, Hamasaki H, Suzuki SO, Ishii T, Ninomiya T, Kira JI, Iwaki T.

J Neuropathol Exp Neurol   80   220 - 228   2021.2

The Association of Small Dense Low-Density Lipoprotein Cholesterol and Coronary Heart Disease in Subjects at High Cardiovascular Risk Reviewed

Higashioka M, Sakata S, Honda T, Hata J, Shibata M, Yoshida D, Goto K, Kitazono T, Osawa H, Ninomiya T.

J Atheroscler Thromb   28   79 - 89   2021.1

N-Terminal Pro-B-Type Natriuretic Peptide and Incident CKD Reviewed

Sasaki T, Oishi E, Nagata T, Sakata S, Chen S, Furuta Y, Honda T, Yoshida D, Hata J, Tsuboi N, Kitazono T, Yokoo T, Ninomiya T.

Kidney Int Rep   6   976 - 985   2021.1

Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study Reviewed

Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T.

Int J Cardiol   320   90 - 96   2020.12

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) Reviewed

Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y; JPSFC-AD Study Group.

Environ Health Prev Med   25   64 - 64   2020.12

Influence of the Accumulation of Unhealthy Eating Habits on Obesity in a General Japanese Population: The Hisayama Study Reviewed

Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazono T, Ninomiya T.

Nutrients   12   3160 - 3160   2020.12

Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: The Hisayama Study Reviewed

Mihara A, Ohara T, Hata J, Honda T, Chen S, Sakata S, Oishi E, Hirakawa Y, Nakao T, Kitazono T, Ninomiya T.

Atherosclerosis   311   52 - 59   2020.12

Growth Differentiation Factor 15 and NT-proBNP as Blood-Based Markers of Vascular Brain Injury and Dementia Reviewed

McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S.

J Am Heart Assoc   9   e014659 - e014659   2020.12

Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS) Reviewed

Asayama K, Tabara Y, Oishi E, Sakata S, Hisamatsu T, Godai K, Kabayama M, Tatsumi Y, Hata J, Kikuya M, Kamide K, Miura K, Ninomiya T, Ohkubo T.

Hypertens Res   43   1403 - 1412   2020.12

Impact of hypertension stratified by diabetes on the lifetime risk of cardiovascular disease mortality in Japan: a pooled analysis of data from the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan study Reviewed

Imai Y, Hirata T, Saitoh S, Ninomiya T, Miyamoto Y, Ohnishi H, Murakami Y, Iso H, Tanaka S, Miura K, Tamakoshi A, Yamada M, Kiyama M, Ueshima H, Ishikawa S, Okamura T; Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group.

Hypertens Res   43   1437 - 1444   2020.12

Usefulness of the SAGE score to predict elevated values of brachial-ankle pulse wave velocity in Japanese subjects with hypertension Reviewed

Tomiyama H, Vlachopoulos C, Xaplanteris P, Nakano H, Shiina K, Ishizu T, Kohro T, Higashi Y, Takase B, Suzuki T, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Tanaka A, Maemura K, Ohya Y, Furukawa T, Ito H, Ohkuma T, Ninomiya T, Chikamori T, Yamashina A, Ueda SI.

Hypertens Res   43   1284 - 1292   2020.11

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: The Hisayama Study Reviewed

Inaishi J, Saisho Y, Hirakawa Y, Yoshida D, Hata J, Mukai N, Watanabe Y, Oda Y, Itoh H, Ninomiya T.

J Diabetes Investig   11   1197 - 1206   2020.9

Five-Year Incidence of Myopic Maculopathy in a General Japanese Population: The Hisayama Study Reviewed

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH.

JAMA Ophthalmol   138   887 - 893   2020.8

Nephron Number and Time to Remission in Steroid-Sensitive Minimal Change Disease Reviewed

Sasaki T, Tsuboi N, Marumoto H, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Ogura M, Ninomiya T, Yokoo T.

Kidney Med   2   559 - 568   2020.8

Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan Reviewed

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Furuta Y, Oishi E, Sakata S, Kanba S, Kitazono T, Ninomiya T.

Neurology   95   e508 - e518   2020.8

Small Dense Low-Density Lipoprotein Cholesterol and the Risk of Coronary Heart Disease in a Japanese Community Reviewed

Higashioka M, Sakata S, Honda T, Hata J, Yoshida D, Hirakawa Y, Shibata M, Goto K, Kitazono T, Osawa H, Ninomiya T.

J Atheroscler Thromb   27   669 - 682   2020.7

Parenting style during childhood is associated with the development of chronic pain and a patient's need for psychosomatic treatment in adulthood: A case-control study Reviewed

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M.

Medicine (Baltimore)   99   e21230 - e21230   2020.7

30-minute postload plasma glucose levels during an oral glucose tolerance test predict the risk of future type 2 diabetes: the Hisayama Study Reviewed

Hirakawa Y, Hata J, Yoshinari M, Higashioka M, Yoshida D, Shibata M, Honda T, Sakata S, Kato H, Teramoto T, Maki H, Nishimoto S, Kitazono T, Ninomiya T.

BMJ Open Diabetes Res Care   8   e001156 - e001156   2020.7

Elevated serum glycated albumin and glycated albumin : hemoglobin A(1c) ratio were associated with hippocampal atrophy in a general elderly population of Japanese: The Hisayama Study Reviewed

Ohara T, Furuta Y, Hirabayashi N, Hata J, Hirakawa Y, Honda T, Yoshida D, Shibata M, Kitazono T, Ninomiya T.

J Diabetes Investig   11   971 - 979   2020.7

Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study Reviewed

Sakata S, Hata J, Honda T, Hirakawa Y, Oishi E, Shibata M, Yoshida D, Goto K, Kitazono T, Ninomiya T.

Hypertens Res   43   560 - 568   2020.6

Serum homocysteine and risk of dementia in Japan Reviewed

Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Sakata S, Oishi E, Furuta Y, Kitazono T, Ninomiya T.

J Neurol Neurosurg Psychiatry   91   540 - 546   2020.5

Association of Albuminuria With White Matter Hyperintensities Volume on Brain Magnetic Resonance Imaging in Elderly Japanese　- The Hisayama Study Reviewed

Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T.

Circ J   84   935 - 942   2020.5

Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia Reviewed

Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, Bjertness E, Chalmers J, Clarke R, Dartigues JF, Davis-Plourde K, Debette S, Di Angelantonio E, Feart C, Frikke-Schmidt R, Gregson J, Haan MN, Hassing LB, Hayden KM, Hoevenaar-Blom MP, Kaprio J, Kivimaki M, Lappas G, Larson EB, LeBlanc ES, Lee A, Lui LY, Moll van Charante EP, Ninomiya T, Nordestgaard LT, Ohara T, Ohkuma T, Palviainen T, Peres K, Peters R, Qizilbash N, Richard E, Rosengren A, Seshadri S, Shipley M, Singh-Manoux A, Strand BH, van Gool WA, Vuoksimaa E, Yaffe K, Huxley RR.

Obes Rev   21   e12989 - e12989   2020.4

Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: The Hisayama Study Reviewed

Higashioka M, Hirakawa Y, Kawamura R, Honda T, Hata J, Yoshida D, Takata Y, Kitazono T, Osawa H, Ninomiya T.

J Diabetes Investig   11   482 - 489   2020.3

Disrupted tongue microbiota and detection of nonindigenous bacteria on the day of allogeneic hematopoietic stem cell transplantation Reviewed

Oku S, Takeshita T, Futatsuki T, Kageyama S, Asakawa M, Mori Y, Miyamoto T, Hata J, Ninomiya T, Kashiwazaki H, Yamashita Y.

PLoS Pathog   16   e1008348 - e1008348   2020.3

Genome-Wide Polygenic Score and the Risk of Ischemic Stroke in a Prospective Cohort: The Hisayama Study Reviewed

Hachiya T, Hata J, Hirakawa Y, Yoshida D, Furuta Y, Kitazono T, Shimizu A, Ninomiya T.

Stroke   51   759 - 765   2020.3

Dietary Inflammatory Index Positively Associated With High-Sensitivity C-Reactive Protein Level in Japanese From NIPPON DATA2010 Reviewed

Yang Y, Hozawa A, Kogure M, Narita A, Hirata T, Nakamura T, Tsuchiya N, Nakaya N, Ninomiya T, Okuda N, Kadota A, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K.

J Epidemiol   30   98 - 107   2020.2

Decline in Handgrip Strength From Midlife to Late-Life is Associated With Dementia in a Japanese Community: The Hisayama Study Reviewed

Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T.

J Epidemiol   30   15 - 23   2020.1

CORRIGENDUM: Association of Albuminuria With White Matter Hyperintensities Volume on Brain Magnetic Resonance Imaging in Elderly Japanese　- The Hisayama Study Reviewed

Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T.

Circ J   84   1207 - 1207   2020.1

Association between Axial Length and Myopic Maculopathy: The Hisayama Study Reviewed

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Hata J, Hirakawa Y, Ninomiya T, Sonoda KH.

Ophthalmol Retina   3   867 - 873   2019.12

Brachial-Ankle Pulse Wave Velocity Versus Its Stiffness Index β-Transformed Value as Risk Marker for Cardiovascular Disease Reviewed

Tomiyama H, Ohkuma T, Ninomiya T, Nakano H, Matsumoto C, Avolio A, Kohro T, Higashi Y, Maruhashi T, Takase B, Suzuki T, Ishizu T, Ueda S, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Maemura K, Ohya Y, Furukawa T, Ito H, Chikamori T, Yamashina A.

J Am Heart Assoc   8   e013004 - e013004   2019.12

Estimation of nephron number in living humans by combining unenhanced computed tomography with biopsy-based stereology Reviewed

Sasaki T, Tsuboi N, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Kobayashi A, Yamamoto I, Takahashi S, Ninomiya T, Shimizu A, Rule AD, Bertram JF, Yokoo T.

Sci Rep   9   14400 - 14400   2019.12

Long-term regular exercise and intraocular pressure: the Hisayama Study Reviewed

Fujiwara K, Yasuda M, Hata J, Yoshida D, Kishimoto H, Hashimoto S, Yoshitomi T, Ninomiya T, Sonoda KH.

Graefes Arch Clin Exp Ophthalmol   257   2461 - 2469   2019.11

Serum Lipopolysaccharide-Binding Protein Levels and the Incidence of Cardiovascular Disease in a General Japanese Population: The Hisayama Study Reviewed

Asada M, Oishi E, Sakata S, Hata J, Yoshida D, Honda T, Furuta Y, Shibata M, Suzuki K, Watanabe H, Murayama N, Kitazono T, Yamaura K, Ninomiya T.

J Am Heart Assoc   8   e013628 - e013628   2019.11

Serum elaidic acid concentration and risk of dementia: The Hisayama Study Reviewed

Honda T, Ohara T, Shinohara M, Hata J, Toh R, Yoshida D, Shibata M, Ishida T, Hirakawa Y, Irino Y, Sakata S, Uchida K, Kitazono T, Kanba S, Hirata KI, Ninomiya T.

Neurology   93   e2053 - e2064   2019.11

Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study Reviewed

Fujiwara K, Yasuda M, Hata J, Hirakawa Y, Hashimoto S, Ueda E, Iwase A, Araie M, Yoshitomi T, Ninomiya T, Sonoda KH.

Am J Ophthalmol   205   140 - 146   2019.9

NT-proBNP and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study Reviewed

Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T.

J Am Heart Assoc   8   e011652 - e011652   2019.9

Association Between Serum β-Alanine and Risk of Dementia Reviewed

Hata J, Ohara T, Katakura Y, Shimizu K, Yamashita S, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Kitazono T, Kuhara S, Ninomiya T.

Am J Epidemiol   188   1637 - 1645   2019.9

Reduced Estimated GFR and Cardiac Remodeling: A Population-Based Autopsy Study Reviewed

Izumaru K, Hata J, Nakano T, Nakashima Y, Nagata M, Fukuhara M, Oda Y, Kitazono T, Ninomiya T.

Am J Kidney Dis   74   373 - 381   2019.9

Association Between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study Reviewed

Inaishi J, Hirakawa Y, Horikoshi M, Akiyama M, Higashioka M, Yoshinari M, Hata J, Mukai N, Kamatani Y, Momozawa Y, Kubo M, Ninomiya T.

J Clin Endocrinol Metab   104   3213 - 3222   2019.8

Characteristics of the Salivary Microbiota in Patients With Various Digestive Tract Cancers Reviewed

Kageyama S, Takeshita T, Takeuchi K, Asakawa M, Matsumi R, Furuta M, Shibata Y, Nagai K, Ikebe M, Morita M, Masuda M, Toh Y, Kiyohara Y, Ninomiya T, Yamashita Y.

Front Microbiol   10   1780 - 1780   2019.8

Dietary Sodium Reduction Reduces Albuminuria: A Cluster Randomized Trial Reviewed

Jardine MJ, Li N, Ninomiya T, Feng X, Zhang J, Shi J, Zhang Y, Zhang R, Zhang J, Hao J, Perkovic V, Heerspink HL, Wu Y, Yan LL, Neal B.

J Ren Nutr   29   276 - 284   2019.7

Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study Reviewed

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH.

Invest Ophthalmol Vis Sci   60   2781 - 2786   2019.7

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Reviewed

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, et al.

Nat Genet   51   1192 - 1193   2019.7

Serum Ethylamine Levels as an Indicator of l-Theanine Consumption and the Risk of Type 2 Diabetes in a General Japanese Population: The Hisayama Study Reviewed

Ninomiya T, Kanzaki N, Hirakawa Y, Yoshinari M, Higashioka M, Honda T, Shibata M, Sakata S, Yoshida D, Teramoto T, Takemoto S, Nishimoto S, Hata J, Kitazono T.

Diabetes Care   42   1234 - 1240   2019.7

Physical component quality of life reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 quality of life: An AusDiab analysis Reviewed

Wong MG, Ninomiya T, Liyanage T, Sukkar L, Hirakawa Y, Wang Y, Wyld MLR, Morton RL, Chadban S, Howard K, Jardine MJ.

Nephrology (Carlton)   24   605 - 614   2019.6

Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study Reviewed

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T.

Am J Clin Nutr   109   1664 - 1671   2019.6

Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer's disease: The Hisayama study Reviewed

Hamasaki H, Honda H, Suzuki SO, Shijo M, Ohara T, Hatabe Y, Okamoto T, Ninomiya T, Iwaki T.

Alzheimers Dement (Amst)   11:415-423   415 - 423   2019.6

Objectively measured sedentary time and diabetes mellitus in a general Japanese population: The Hisayama Study Reviewed

Honda T, Kishimoto H, Mukai N, Hata J, Yoshida D, Hirakawa Y, Shibata M, Ohara T, Kumagai S, Ninomiya T.

J Diabetes Investig   10   809 - 816   2019.5

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality Reviewed

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K, Yang WS, Zhou X, Baylin A, Boer JMA, Brouwer IA, Campos H, Chaves PHM, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, El-Abbadi N, Forouhi NG, Michael Gaziano J, Geleijnse JM, Gigante B, Giles G, Guallar E, Gudnason V, Harris T, Harris WS, Helmer C, Hellenius ML, Hodge A, Hu FB, Jacques PF, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, Luo J, McKnight B, Mursu J, Ninomiya T, Overvad K, Psaty BM, Rimm E, Schulze MB, Siscovick D, Skjelbo Nielsen M, Smith AV, Steffen BT, Steffen L, Sun Q, Sundström J, Tsai MY, Tunstall-Pedoe H, Uusitupa MIJ, van Dam RM, Veenstra J, Monique Verschuren WM, Wareham N, Willett W, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Risérus U; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE).

Circulation   139   2422 - 2436   2019.5

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis Reviewed

Toyama T, Neuen BL, Jun M, Ohkuma T, Neal B, Jardine MJ, Heerspink HL, Wong MG, Ninomiya T, Wada T, Perkovic V.

Diabetes Obes Metab   21   1237 - 1250   2019.5

Steno-Stiffness Approach for Cardiovascular Disease Risk Assessment in Primary Prevention Reviewed

Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A; Collaborative Group for J-BAVELs (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies).

Hypertension   73   508 - 513   2019.3

Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study Reviewed

Ogata H, Hirakawa Y, Matsumoto K, Hata J, Yoshida D, Fukuyama S, Inoue H, Kitazono T, Ninomiya T, Nakanishi Y.

BMJ Open   9   e023673 - e023673   2019.3

Longitudinal Changes of Physical Activity and Sedentary Time in the Middle-Aged and Older Japanese Population: The Hisayama Study Reviewed

Yonemoto K, Honda T, Kishimoto H, Yoshida D, Hata J, Mukai N, Shibata M, Hirakawa Y, Ninomiya T, Kumagai S.

J Phys Act Health   16   165 - 171   2019.2

Cardiovascular Risk Factors Associated With Venous Thromboembolism Reviewed

Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P, Burgess S, Bell S, Sweeting M, Rimm EB, Kabrhel C, Zöller B, Assmann G, Gudnason V, Folsom AR, Arndt V, Fletcher A, Norman PE, Nordestgaard BG, Kitamura A, Mahmoodi BK, Whincup PH, Knuiman M, Salomaa V, Meisinger C, Koenig W, Kavousi M, Völzke H, Cooper JA, Ninomiya T, Casiglia E, Rodriguez B, Ben-Shlomo Y, Després JP, Simons L, Barrett-Connor E, Björkelund C, Notdurfter M, Kromhout D, Price J, Sutherland SE, Sundström J, Kauhanen J, Gallacher J, Beulens JWJ, Dankner R, Cooper C, Giampaoli S, Deen JF, Gómez de la Cámara A, Kuller LH, Rosengren A, Svensson PJ, Nagel D, Crespo CJ, Brenner H, Albertorio-Diaz JR, Atkins R, Brunner EJ, Shipley M, Njølstad I, Lawlor DA, van der Schouw YT, Selmer RM, Trevisan M, Verschuren WMM, Greenland P, Wassertheil-Smoller S, Lowe GDO, Wood AM, Butterworth AS, Thompson SG, Danesh J, Di Angelantonio E, Meade T; Emerging Risk Factors Collaboration.

JAMA Cardiol   4   163 - 173   2019.2

Serum soluble triggering receptor expressed on myeloid cells 2 as a biomarker for incident dementia: the Hisayama Study. Invited Reviewed International journal

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T

Ann Neurol   85   47 - 58   2019.1

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study Reviewed

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T.

Ann Neurol   85   47 - 58   2019.1

Prevalence of adult epilepsy in a general Japanese population: The Hisayama study Reviewed

Tanaka A, Hata J, Akamatsu N, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Ohara T, Mizuno T, Tsuji S, Kitazono T, Ninomiya T.

Epilepsia Open   4   182 - 186   2019.1

Apparent Treatment-Resistant Hypertension and Cardiovascular Risk in Hemodialysis Patients: Ten-Year Outcomes of the Q-Cohort Study Reviewed

Tanaka S, Ninomiya T, Hiyamuta H, Taniguchi M, Tokumoto M, Masutani K, Ooboshi H, Nakano T, Tsuruya K, Kitazono T.

Sci Rep   9   1043 - 1043   2019.1

Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis Reviewed

Okazaki S, Morimoto T, Kamatani Y, Kamimura T, Kobayashi H, Harada K, Tomita T, Higashiyama A, Takahashi JC, Nakagawara J, Koga M, Toyoda K, Washida K, Saito S, Takahashi A, Hirata M, Matsuda K, Mochizuki H, Chong M, Paré G, O'Donnell M, Ago T, Hata J, Ninomiya T, Dichgans M, Debette S, Kubo M, Koizumi A, Ihara M.

Circulation   139   295 - 298   2019.1

Having few remaining teeth is associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese individuals: findings from the NIPPON DATA2010 Reviewed

Nakamura M, Ojima T, Nagahata T, Kondo I, Ninomiya T, Yoshita K, Arai Y, Ohkubo T, Murakami K, Nishi N, Murakami Y, Takashima N, Okuda N, Kadota A, Miyagawa N, Kondo K, Okamura T, Ueshima H, Okayama A, Miura K; NIPPON DATA2010 Research Group.

Environ Health Prev Med   24   1 - 1   2019.1

Association Between Daily Sleep Duration and Risk of Dementia and Mortality in a Japanese Community Reviewed

Ohara T, Honda T, Hata J, Yoshida D, Mukai N, Hirakawa Y, Shibata M, Kishimoto H, Kitazono T, Kanba S, Ninomiya T.

J Am Geriatr Soc   66   1911 - 1918   2018.12

Distribution of nephrologists and regional variation in the clinical severity of IgA nephropathy at biopsy diagnosis in Japan: a cross-sectional study Reviewed

Okabayashi Y, Tsuboi N, Amano H, Miyazaki Y, Kawamura T, Ogura M, Narita I, Ninomiya T, Yokoyama H, Yokoo T.

BMJ Open   8   e024317 - e024317   2018.12

A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: The Hisayama study Reviewed

Tanaka M, Honda T, Yamakage H, Hata J, Yoshida D, Hirakawa Y, Shibata M, Inoue T, Kusakabe T, Satoh-Asahara N, Ninomiya T.

Diabetes Res Clin Pract   146   225 - 232   2018.12

Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: The Hisayama Study Reviewed

Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

Atherosclerosis   279   38 - 44   2018.12

Trends in the prevalence of type 2 diabetes and prediabetes in a Japanese community, 1988-2012: the Hisayama Study Reviewed

Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Nakamura U, Kitazono T, Ninomiya T.

Diabetol Int   10   198 - 205   2018.11

Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: the Hisayama Study. Invited Reviewed International journal

Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T

Atherosclerosis   279   38 - 44   2018.10

Association between the ratio of serum arachidonic acid to eicosapentaenoic acid and the presence of depressive symptoms in a general Japanese population: the Hisayama Study Reviewed

Shibata M, Ohara T, Yoshida D, Hata J, Mukai N, Kawano H, Kanba S, Kitazono T, Ninomiya T.

J Affect Disord   237   73 - 79   2018.9

Periodontal status and lung function decline in the community: the Hisayama study Reviewed

Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y.

Sci Rep   8   13354 - 13354   2018.9

Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis Reviewed

Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A; collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI).

Atherosclerosis   275   141 - 148   2018.8

Tongue Microbiota and Oral Health Status in Community-Dwelling Elderly Adults Reviewed

Asakawa M, Takeshita T, Furuta M, Kageyama S, Takeuchi K, Hata J, Ninomiya T, Yamashita Y.

mSphere   3   e00332-18 - e00332-18   2018.8

Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes Reviewed

Oshima M, Toyama T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Hara A, Makino H, Wada T; Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan.

PLoS One   13   e0201535 - e0201535   2018.8

Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer's disease Reviewed

Yamaguchi-Kabata Y, Morihara T, Ohara T, Ninomiya T, Takahashi A, Akatsu H, Hashizume Y, Hayashi N, Shigemizu D, Boroevich KA, Ikeda M, Kubo M, Takeda M, Tsunoda T.

Hum Genet   137   521 - 533   2018.7

Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy Reviewed

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K.

Nephrol Dial Transplant   33   963 - 971   2018.6

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community Reviewed

Yubi T, Hata J, Ohara T, Mukai N, Hirakawa Y, Yoshida D, Gotoh S, Hirabayashi N, Furuta Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Neurol Clin Pract   8   223 - 231   2018.6

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study Reviewed

Furuta Y, Hata J, Mukai N, Hirakawa Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Atherosclerosis   273   84 - 90   2018.6

Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis Reviewed

Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; collaborative group for J-BAVEL-IAD (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies to Examine the Significance of Inter-Arm Blood Pressure Difference).

Hypertension   71   1030 - 1038   2018.6

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population Reviewed

Iida M, Ikeda F, Hata J, Hirakawa Y, Ohara T, Mukai N, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T.

Gastric Cancer   21   383 - 390   2018.5

Patterns and Levels of Sedentary Behavior and Physical Activity in a General Japanese Population: The Hisayama Study Reviewed

Chen T, Kishimoto H, Honda T, Hata J, Yoshida D, Mukai N, Shibata M, Ninomiya T, Kumagai S.

J Epidemiol   28   260 - 265   2018.5

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Reviewed

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, et al.

Nat Genet   50   524 - 537   2018.4

Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration Reviewed

Peters SAE, Wang X, Lam TH, Kim HC, Ho S, Ninomiya T, Knuiman M, Vaartjes I, Bots ML, Woodward M; Asia Pacific Cohort Studies Collaboration.

BMJ Open   8   e019335 - e019335   2018.3

Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi Reviewed

Shijo M, Honda H, Suzuki SO, Hamasaki H, Hokama M, Abolhassani N, Nakabeppu Y, Ninomiya T, Kitazono T, Iwaki T.

Brain Pathol   28   58 - 71   2018.1

Prevalence and Risk Factors for Polypoidal Choroidal Vasculopathy in a General Japanese Population: The Hisayama Study Reviewed

Fujiwara K, Yasuda M, Hata J, Oshima Y, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T, Ninomiya T, Sonoda KH.

Semin Ophthalmol   33   813 - 819   2018.1

Albuminuria Increases the Risks for Both Alzheimer Disease and Vascular Dementia in Community-Dwelling Japanese Elderly: The Hisayama Study Reviewed

Takae K, Hata J, Ohara T, Yoshida D, Shibata M, Mukai N, Hirakawa Y, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T.

J Am Heart Assoc   7   e006693 - e006693   2018.1

Morning and Evening Blood Pressures Are Associated With Intima-Media Thickness in a General Population　- The Hisayama Study Reviewed

Sakata S, Hata J, Fukuhara M, Yonemoto K, Mukai N, Yoshida D, Kishimoto H, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T.

Circ J   81   1647 - 1653   2017.12

Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation Reviewed

Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y.

Sci Rep   7   17762 - 17762   2017.12

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: The Hisayama Study Reviewed

Nagata M, Hata J, Hirakawa Y, Mukai N, Yoshida D, Ohara T, Kishimoto H, Kawano H, Kitazono T, Kiyohara Y, Ninomiya T.

J Epidemiol   27   578 - 583   2017.12

Exploration of bacterial species associated with the salivary microbiome of individuals with a low susceptibility to dental caries Reviewed

Yasunaga H, Takeshita T, Shibata Y, Furuta M, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Takahashi I, Yamashita Y.

Clin Oral Investig   21   2399 - 2406   2017.11

Impact of blood urea nitrogen to creatinine ratio on mortality and morbidity in hemodialysis patients: The Q-Cohort Study Reviewed

Tanaka S, Ninomiya T, Taniguchi M, Tokumoto M, Masutani K, Ooboshi H, Kitazono T, Tsuruya K.

Sci Rep   7   14901 - 14901   2017.11

White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study Reviewed

Hata J, Fukuhara M, Sakata S, Arima H, Hirakawa Y, Yonemoto K, Mukai N, Kitazono T, Kiyohara Y, Ninomiya T.

Hypertens Res   40   937 - 943   2017.11

Association of Airflow Limitation With Carotid Atherosclerosis in a Japanese Community　- The Hisayama Study Reviewed

Kudo K, Hata J, Matsumoto K, Shundo Y, Fukuyama S, Inoue H, Kitazono T, Kiyohara Y, Ninomiya T, Nakanishi Y.

Circ J   81   1846 - 1853   2017.11

Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension Reviewed

Ohkuma T, Tomiyama H, Ninomiya T, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies (J-BAVEL).

Circ J   81   1540 - 1542   2017.9

Association Between Serum Vitamin D and All-Cause and Cause-Specific Death in a General Japanese Population　- The Hisayama Study Reviewed

Umehara K, Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Kishimoto H, Kitazono T, Hoka S, Kiyohara Y, Ninomiya T.

Circ J   81   1315 - 1321   2017.8

Day-to-Day Blood Pressure Variability and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study Reviewed

Oishi E, Ohara T, Sakata S, Fukuhara M, Hata J, Yoshida D, Shibata M, Ohtsubo T, Kitazono T, Kiyohara Y, Ninomiya T.

Circulation   136   516 - 525   2017.8

Alternative Measures of Hyperglycemia and Risk of Alzheimer's Disease in the Community: The Hisayama Study Reviewed

Mukai N, Ohara T, Hata J, Hirakawa Y, Yoshida D, Kishimoto H, Koga M, Nakamura U, Kitazono T, Kiyohara Y, Ninomiya T.

J Clin Endocrinol Metab   102   3002 - 3010   2017.8

Serum Non-High-Density Lipoprotein Cholesterol and Risk of Cardiovascular Disease in Community Dwellers with Chronic Kidney Disease: the Hisayama Study Reviewed

Usui T, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Kitazono T, Kiyohara Y, Ninomiya T.

J Atheroscler Thromb   24   706 - 715   2017.7

Chronic kidney disease in Asia: Protocol for a collaborative overview Reviewed

Liyanage T, Ninomiya T, Perkovic V, Woodward M, Stirnadel-Farrant H, Matsushita K, Iseki K, Seong HL, Monaghan H, Jha V.

Nephrology (Carlton)   22   456 - 462   2017.6

The Contribution of Inflammation to the Development of Hypertension Mediated by Increased Arterial Stiffness Reviewed

Tomiyama H, Shiina K, Matsumoto-Nakano C, Ninomiya T, Komatsu S, Kimura K, Chikamori T, Yamashina A.

J Am Heart Assoc   6   e005729 - e005729   2017.6

Dietary Protein Intake and Stroke Risk in a General Japanese Population: The Hisayama Study Reviewed

Ozawa M, Yoshida D, Hata J, Ohara T, Mukai N, Shibata M, Uchida K, Nagata M, Kitazono T, Kiyohara Y, Ninomiya T.

Stroke   48   1478 - 1486   2017.6

Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis Reviewed

Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A; Collaborative Group for J-BAVEL (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies)*.

Hypertension   69   1045 - 1052   2017.6

The Fukuoka Kidney disease Registry (FKR) Study: design and methods Reviewed

Tanaka S, Ninomiya T, Fujisaki K, Yoshida H, Nagata M, Masutani K, Tokumoto M, Mitsuiki K, Hirakata H, Fujimi S, Kiyohara Y, Kitazono T, Tsuruya K; Fukuoka Kidney disease Registry (FKR) Study Collaboration Group.

Clin Exp Nephrol   21   465 - 473   2017.6

Tooth Loss and Risk of Dementia in the Community: the Hisayama Study Reviewed

Takeuchi K, Ohara T, Furuta M, Takeshita T, Shibata Y, Hata J, Yoshida D, Yamashita Y, Ninomiya T.

J Am Geriatr Soc   65   e95 - e100   2017.5

Development of a self-scored persistent airflow obstruction screening questionnaire in a general Japanese population: the Hisayama study Reviewed

Samukawa T, Matsumoto K, Tsukuya G, Koriyama C, Fukuyama S, Uchida A, Mizuno K, Miyahara H, Kiyohara Y, Ninomiya T, Inoue H.

Int J Chron Obstruct Pulmon Dis   12   1469 - 1481   2017.5

Trends in dementia prevalence, incidence, and survival rate in a Japanese community Reviewed

Ohara T, Hata J, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y, Ninomiya T.

Neurology   88   1925 - 1932   2017.5

Stimulated salivary flow rate and oral health status Reviewed

Shimazaki Y, Fu B, Yonemoto K, Akifusa S, Shibata Y, Takeshita T, Ninomiya T, Kiyohara Y, Yamashita Y.

J Oral Sci   59   55 - 62   2017.3

Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project Reviewed

Nakamura K, Okada E, Ukawa S, Hirata M, Nagai A, Yamagata Z, Kiyohara Y, Muto K, Kamatani Y, Ninomiya T, Matsuda K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Tamakoshi A.

J Epidemiol   27   S58 - S64   2017.3

Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project Reviewed

Ukawa S, Nakamura K, Okada E, Hirata M, Nagai A, Yamagata Z, Muto K, Matsuda K, Ninomiya T, Kiyohara Y, Kamatani Y, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Tamakoshi A.

J Epidemiol   27   S65 - S70   2017.3

Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project Reviewed

Tamakoshi A, Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Matsuda K, Kamatani Y, Muto K, Kiyohara Y, Yamagata Z, Ninomiya T, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group.

J Epidemiol   27   S36 - S42   2017.3

Characteristics of patients with liver cancer in the BioBank Japan project Reviewed

Ukawa S, Okada E, Nakamura K, Hirata M, Nagai A, Matsuda K, Yamagata Z, Kamatani Y, Ninomiya T, Kiyohara Y, Muto K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Tamakoshi A.

J Epidemiol   27   S43 - S48   2017.3

Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort Reviewed

Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Yamagata Z.

J Epidemiol   27   S98 - S106   2017.3

Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project Reviewed

Nakamura K, Ukawa S, Okada E, Hirata M, Nagai A, Yamagata Z, Ninomiya T, Muto K, Kiyohara Y, Matsuda K, Kamatani Y, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Tamakoshi A.

J Epidemiol   27   S49 - S57   2017.3

Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan Reviewed

Yokomichi H, Noda H, Nagai A, Hirata M, Tamakoshi A, Kamatani Y, Kiyohara Y, Matsuda K, Muto K, Ninomiya T, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Yamagata Z.

J Epidemiol   27   S77 - S83   2017.3

Statin use and all-cause and cancer mortality: BioBank Japan cohort Reviewed

Yokomichi H, Nagai A, Hirata M, Tamakoshi A, Kiyohara Y, Kamatani Y, Muto K, Ninomiya T, Matsuda K, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Yamagata Z.

J Epidemiol   27   S84 - S91   2017.3

Overview of BioBank Japan follow-up data in 32 diseases Reviewed

Hirata M, Nagai A, Kamatani Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Kiyohara Y, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group; Matsuda K.

J Epidemiol   27   S22 - S28   2017.3

Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project Reviewed

Okada E, Ukawa S, Nakamura K, Hirata M, Nagai A, Matsuda K, Ninomiya T, Kiyohara Y, Muto K, Kamatani Y, Yamagata Z, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Tamakoshi A.

J Epidemiol   27   S29 - S35   2017.3

Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases Reviewed

Hirata M, Kamatani Y, Nagai A, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Kubo M, Muto K, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group; Matsuda K.

J Epidemiol   27   S9 - S21   2017.3

Overview of the BioBank Japan Project: Study design and profile Reviewed

Nagai A, Hirata M, Kamatani Y, Muto K, Matsuda K, Kiyohara Y, Ninomiya T, Tamakoshi A, Yamagata Z, Mushiroda T, Murakami Y, Yuji K, Furukawa Y, Zembutsu H, Tanaka T, Ohnishi Y, Nakamura Y; BioBank Japan Cooperative Hospital Group; Kubo M.

J Epidemiol   27   S2 - S8   2017.3

Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan Reviewed

Yokomichi H, Nagai A, Hirata M, Kiyohara Y, Muto K, Ninomiya T, Matsuda K, Kamatani Y, Tamakoshi A, Kubo M, Nakamura Y; BioBank Japan Cooperative Hospital Group; Yamagata Z.

J Epidemiol   27   S92 - S97   2017.3

Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project Reviewed

Hata J, Nagai A, Hirata M, Kamatani Y, Tamakoshi A, Yamagata Z, Muto K, Matsuda K, Kubo M, Nakamura Y; Biobank Japan Cooperative Hospital Group; Kiyohara Y, Ninomiya T.

J Epidemiol   27   S71 - S76   2017.3

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN) Reviewed

Hirakawa Y, Ninomiya T, Kiyohara Y, Murakami Y, Saitoh S, Nakagawa H, Okayama A, Tamakoshi A, Sakata K, Miura K, Ueshima H, Okamura T; Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN).

J Epidemiol   27   123 - 129   2017.3

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score Reviewed

Hachiya T, Kamatani Y, Takahashi A, Hata J, Furukawa R, Shiwa Y, Yamaji T, Hara M, Tanno K, Ohmomo H, Ono K, Takashima N, Matsuda K, Wakai K, Sawada N, Iwasaki M, Yamagishi K, Ago T, Ninomiya T, Fukushima A, Hozawa A, Minegishi N, Satoh M, Endo R, Sasaki M, Sakata K, Kobayashi S, Ogasawara K, Nakamura M, Hitomi J, Kita Y, Tanaka K, Iso H, Kitazono T, Kubo M, Tanaka H, Tsugane S, Kiyohara Y, Yamamoto M, Sobue K, Shimizu A.

Stroke   48   253 - 258   2017.2

Recent Increases in Hippocampal Tau Pathology in the Aging Japanese Population: The Hisayama Study Reviewed

Hamasaki H, Honda H, Okamoto T, Koyama S, Suzuki SO, Ohara T, Ninomiya T, Kiyohara Y, Iwaki T.

J Alzheimers Dis   55   613 - 624   2017.1

The effect of renin-angiotensin system blockade on the incidence of end-stage renal disease in IgA nephropathy Reviewed

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Nagata M, Tsuchimoto A, Hirakata H, Kitazono T, Tsuruya K.

Clin Exp Nephrol   20   689 - 698   2016.12

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis Reviewed

Natriuretic Peptides Studies Collaboration, Willeit P, Kaptoge S, Welsh P, Butterworth AS, Chowdhury R, Spackman SA, Pennells L, Gao P, Burgess S, Freitag DF, Sweeting M, Wood AM, Cook NR, Judd S, Trompet S, Nambi V, Olsen MH, Everett BM, Kee F, Ärnlöv J, Salomaa V, Levy D, Kauhanen J, Laukkanen JA, Kavousi M, Ninomiya T, Casas JP, Daniels LB, Lind L, Kistorp CN, Rosenberg J, Mueller T, Rubattu S, Panagiotakos DB, Franco OH, de Lemos JA, Luchner A, Kizer JR, Kiechl S, Salonen JT, Goya Wannamethee S, de Boer RA, Nordestgaard BG, Andersson J, Jørgensen T, Melander O, Ballantyne ChM, DeFilippi Ch, Ridker PM, Cushman M, Rosamond WD, Thompson SG, Gudnason V, Sattar N, Danesh J, Di Angelantonio E.

Lancet Diabetes Endocrinol   4   840 - 849   2016.12

Combination of Helicobacter pylori Antibody and Serum Pepsinogen as a Good Predictive Tool of Gastric Cancer Incidence: 20-Year Prospective Data From the Hisayama Study Reviewed

Ikeda F, Shikata K, Hata J, Fukuhara M, Hirakawa Y, Ohara T, Mukai N, Nagata M, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T.

J Epidemiol   26   629 - 636   2016.12

Association Between Diabetes and Hippocampal Atrophy in Elderly Japanese: The Hisayama Study Reviewed

Hirabayashi N, Hata J, Ohara T, Mukai N, Nagata M, Shibata M, Gotoh S, Furuta Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Kiyohara Y, Ninomiya T.

Diabetes Care   39   1543 - 1549   2016.9

Trends in autopsy-verified dementia prevalence over 29 years of the Hisayama study Reviewed

Honda H, Sasaki K, Hamasaki H, Shijo M, Koyama S, Ohara T, Ninomiya T, Kiyohara Y, Suzuki SO, Iwaki T.

Neuropathology   36   383 - 387   2016.8

Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study Reviewed

Tsukuya G, Samukawa T, Matsumoto K, Fukuyama S, Kumamoto T, Uchida A, Koriyama C, Ninomiya T, Inoue H.

Int J Chron Obstruct Pulmon Dis   11   1903 - 1909   2016.8

Effects of the Mediterranean Diet on Cardiovascular Outcomes-A Systematic Review and Meta-Analysis Reviewed

Liyanage T, Ninomiya T, Wang A, Neal B, Jun M, Wong MG, Jardine M, Hillis GS, Perkovic V.

PLoS One   11   e0159252 - e0159252   2016.8

Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community: The Hisayama Study Reviewed

Hata J, Mukai N, Nagata M, Ohara T, Yoshida D, Kishimoto H, Shibata M, Hirakawa Y, Endo M, Ago T, Kitazono T, Oike Y, Kiyohara Y, Ninomiya T.

Arterioscler Thromb Vasc Biol   36   1686 - 1691   2016.8

Comparison of oral versus intravenous vitamin D receptor activator in reducing infection-related mortality in hemodialysis patients: the Q-Cohort Study Reviewed

Tanaka S, Ninomiya T, Taniguchi M, Fujisaki K, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K.

Nephrol Dial Transplant   31   1152 - 60   2016.7

Perceived inadequate care and excessive overprotection during childhood are associated with greater risk of sleep disturbance in adulthood: the Hisayama Study Reviewed

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M.

BMC Psychiatry   16   215 - 215   2016.7

Serum Uric Acid as a Risk Factor for Chronic Kidney Disease in a Japanese Community　- The Hisayama Study Reviewed

Takae K, Nagata M, Hata J, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T.

Circ J   80   1857 - 62   2016.7

Foveal and Macular Thickness in a Japanese Population: The Hisayama Study Reviewed

Hashimoto S, Yasuda M, Ninomiya T, Hata J, Yoshida D, Tahara-Asakuma T, Hirakawa Y, Arakawa S, Fujiwara K, Kiyohara Y, Ishibashi T.

Ophthalmic Epidemiol   23   202 - 208   2016.6

Renin-Angiotensin System Inhibitors and Kidney and Cardiovascular Outcomes in Patients With CKD: A Bayesian Network Meta-analysis of Randomized Clinical Trials Reviewed

Xie X, Liu Y, Perkovic V, Li X, Ninomiya T, Hou W, Zhao N, Liu L, Lv J, Zhang H, Wang H.

Am J Kidney Dis   67   728 - 741   2016.5

The long-term association between physical activity and risk of dementia in the community: the Hisayama Study Reviewed

Kishimoto H, Ohara T, Hata J, Ninomiya T, Yoshida D, Mukai N, Nagata M, Ikeda F, Fukuhara M, Kumagai S, Kanba S, Kitazono T, Kiyohara Y.

Eur J Epidemiol   31   267 - 274   2016.3

Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia Reviewed

Chatterjee S, Peters SA, Woodward M, Mejia Arango S, Batty GD, Beckett N, Beiser A, Borenstein AR, Crane PK, Haan M, Hassing LB, Hayden KM, Kiyohara Y, Larson EB, Li CY, Ninomiya T, Ohara T, Peters R, Russ TC, Seshadri S, Strand BH, Walker R, Xu W, Huxley RR.

Diabetes Care   39   300 - 307   2016.2

Bacterial diversity in saliva and oral health-related conditions: the Hisayama Study Reviewed

Takeshita T, Kageyama S, Furuta M, Tsuboi H, Takeuchi K, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.

Sci Rep   6   22164 - 22164   2016.2

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis Reviewed

Xie X, Atkins E, Lv J, Bennett A, Neal B, Ninomiya T, Woodward M, MacMahon S, Turnbull F, Hillis GS, Chalmers J, Mant J, Salam A, Rahimi K, Perkovic V, Rodgers A.

Lancet   387   435 - 443   2016.1

Prognostic impact of serum bilirubin level on long-term renal survival in IgA nephropathy Reviewed

Tanaka S, Ninomiya T, Masutani K, Nagata M, Tsuchimoto A, Tsuruya K, Kitazono T.

Clin Exp Nephrol   19   1062 - 1070   2015.12

Insulin Resistance Is a Risk Factor for Increased Intraocular Pressure: The Hisayama Study Reviewed

Fujiwara K, Yasuda M, Ninomiya T, Hata J, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T.

Invest Ophthalmol Vis Sci   56   7983 - 7987   2015.12

Midlife and Late-Life Smoking and Risk of Dementia in the Community: The Hisayama Study Reviewed

Ohara T, Ninomiya T, Hata J, Ozawa M, Yoshida D, Mukai N, Nagata M, Iwaki T, Kitazono T, Kanba S, Kiyohara Y.

J Am Geriatr Soc   63   2332 - 2339   2015.11

Hematocrit and the risk of cardiovascular disease in a Japanese community: The Hisayama Study Reviewed

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Ago T, Kitazono T, Kiyohara Y.

Atherosclerosis   242   199 - 204   2015.9

A genome-wide association study of late-onset Alzheimer's disease in a Japanese population Reviewed

Hirano A, Ohara T, Takahashi A, Aoki M, Fuyuno Y, Ashikawa K, Morihara T, Takeda M, Kamino K, Oshima E, Okahisa Y, Shibata N, Arai H, Akatsu H, Ikeda M, Iwata N, Ninomiya T, Monji A, Kitazono T, Kiyohara Y, Kubo M, Kanba S.

Psychiatr Genet   25   139 - 146   2015.8

Serum antibody to Porphyromonas gingivalis and periodontitis progression: the Hisayama Study Reviewed

Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.

J Clin Periodontol   42   719 - 725   2015.8

Health-related quality of life in survivors of acute kidney injury: The Prolonged Outcomes Study of the Randomized Evaluation of Normal versus Augmented Level Replacement Therapy study outcomes Reviewed

Wang AY, Bellomo R, Cass A, Finfer S, Gattas D, Myburgh J, Chadban S, Hirakawa Y, Ninomiya T, Li Q, Lo S, Barzi F, Sukkar L, Jardine M, Gallagher MP; POST-RENAL Study Investigators and the ANZICS Clinical Trials Group.

Nephrology (Carlton)   20   492 - 498   2015.7

Paternal and maternal bonding styles in childhood are associated with the prevalence of chronic pain in a general adult population: the Hisayama Study Reviewed

Anno K, Shibata M, Ninomiya T, Iwaki R, Kawata H, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M.

BMC Psychiatry   15   181 - 181   2015.7

Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study Reviewed

Mukai N, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   14   84 - 84   2015.6

Worldwide access to treatment for end-stage kidney disease: a systematic review Reviewed

Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, Zhao MH, Lv J, Garg AX, Knight J, Rodgers A, Gallagher M, Kotwal S, Cass A, Perkovic V.

Lancet   385   1975 - 1982   2015.5

Interventions for lowering plasma homocysteine levels in kidney transplant recipients Reviewed

Kang A, Nigwekar SU, Perkovic V, Kulshrestha S, Zoungas S, Navaneethan SD, Cass A, Gallagher MP, Ninomiya T, Strippoli GF, Jardine MJ.

Cochrane Database Syst Rev   2015   CD007910 - CD007910   2015.5

Worldwide access to treatment for end-stage kidney disease: a systematic review Reviewed International journal

Liyanage T, Ninomiya T (Double first author), Jha V, Neal B, Patrice HM, Okpechi I, Zhao MH, Lv J, Garg AX, Knight J, Rodgers A, Gallagher M, Kotwal S, Cass A, Perkovic V

Lancet   6736   61601 - 61609   2015.5

Hyporesponsiveness to erythropoiesis-stimulating agent as a prognostic factor in Japanese hemodialysis patients: the Q-Cohort study Reviewed

Eriguchi R, Taniguchi M, Ninomiya T, Hirakata H, Fujimi S, Tsuruya K, Kitazono T.

J Nephrol   28   217 - 225   2015.4

Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the hisayama study Reviewed

Kondo H, Ninomiya T, Hata J, Hirakawa Y, Yonemoto K, Arima H, Nagata M, Tsuruya K, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   22   390 - 403   2015.1

A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles Reviewed

Nakamura K, Ago T, Tsuchimoto A, Noda N, Nakamura A, Ninomiya T, Uchiumi T, Tsuruya K, Kamouchi M, Ooboshi H, Kitazono T.

Case Rep Neurol Med   2015   431461 - 431461   2015.1

Risk factors for reduced salivary flow rate in a Japanese population: the Hisayama Study Reviewed

Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y.

Biomed Res Int   2015   381821 - 381821   2015.1

Dietary patterns and clinical outcomes in hemodialysis patients in Japan: a cohort study Reviewed

Tsuruya K, Fukuma S, Wakita T, Ninomiya T, Nagata M, Yoshida H, Fujimi S, Kiyohara Y, Kitazono T, Uchida K, Shirota T, Akizawa T, Akiba T, Saito A, Fukuhara S.

PLoS One   10   e0116677 - e0116677   2015.1

Validation of a COPD screening questionnaire and establishment of diagnostic cut-points in a Japanese general population: the Hisayama study Reviewed

Tsukuya G, Matsumoto K, Fukuyama S, Crawford B, Nakanishi Y, Ichinose M, Machida K, Samukawa T, Ninomiya T, Kiyohara Y, Inoue H; Hisayama Pulmonary Physiology Study Group.

Allergol Int   64   49 - 53   2015.1

Angiotensin-converting enzyme inhibitor usage and acute kidney injury: a secondary analysis of RENAL study outcomes Reviewed

Wang AY, Bellomo R, Ninomiya T, Lo S, Cass A, Jardine M, Gallagher M; RENAL Study Investigators; ANZICS Clinical Trials Group.

Nephrology (Carlton)   19   617 - 622   2014.12

Distinct composition of the oral indigenous microbiota in South Korean and Japanese adults Reviewed

Takeshita T, Matsuo K, Furuta M, Shibata Y, Fukami K, Shimazaki Y, Akifusa S, Han DH, Kim HD, Yokoyama T, Ninomiya T, Kiyohara Y, Yamashita Y.

Sci Rep   4   6990 - 6990   2014.11

Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study Reviewed

Hokama M, Oka S, Leon J, Ninomiya T, Honda H, Sasaki K, Iwaki T, Ohara T, Sasaki T, LaFerla FM, Kiyohara Y, Nakabeppu Y.

Cereb Cortex   24   2476 - 88   2014.9

Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes Reviewed

Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H; Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan.

Clin Exp Nephrol   18   613 - 620   2014.8

Impact of visit-to-visit glycemic variability on the risks of macrovascular and microvascular events and all-cause mortality in type 2 diabetes: the ADVANCE trial Reviewed

Hirakawa Y, Arima H, Zoungas S, Ninomiya T, Cooper M, Hamet P, Mancia G, Poulter N, Harrap S, Woodward M, Chalmers J.

Diabetes Care   37   2359 - 2365   2014.8

Midlife and late-life handgrip strength and risk of cause-specific death in a general Japanese population: the Hisayama Study Reviewed

Kishimoto H, Hata J, Ninomiya T, Nemeth H, Hirakawa Y, Yoshida D, Kumagai S, Kitazono T, Kiyohara Y.

J Epidemiol Community Health   68   663 - 668   2014.7

Milk and dairy consumption and risk of dementia in an elderly Japanese population: the Hisayama Study Reviewed

Ozawa M, Ohara T, Ninomiya T, Hata J, Yoshida D, Mukai N, Nagata M, Uchida K, Shirota T, Kitazono T, Kiyohara Y.

J Am Geriatr Soc   62   1224 - 1230   2014.7

Effect of hemodiafiltration or hemofiltration compared with hemodialysis on mortality and cardiovascular disease in chronic kidney failure: a systematic review and meta-analysis of randomized trials Reviewed

Wang AY, Ninomiya T, Al-Kahwa A, Perkovic V, Gallagher MP, Hawley C, Jardine MJ.

Am J Kidney Dis   63   968 - 978   2014.6

Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression Reviewed

Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, Ninomiya T, Horiguchi H, Endo M, Tabata M, Tazume H, Tian Z, Takahashi O, Terada K, Takeya M, Hao H, Hirose N, Minami T, Suda T, Kiyohara Y, Ogawa H, Kaikita K, Oike Y.

Arterioscler Thromb Vasc Biol   34   790 - 800   2014.4

Non-high-density lipoprotein cholesterol and the development of coronary heart disease and stroke subtypes in a general Japanese population: the Hisayama Study Reviewed

Imamura T, Doi Y, Ninomiya T, Hata J, Nagata M, Ikeda F, Mukai N, Hirakawa Y, Yoshida D, Fukuhara M, Kitazono T, Kiyohara Y.

Atherosclerosis   233   343 - 348   2014.4

Alexithymia is associated with greater risk of chronic pain and negative affect and with lower life satisfaction in a general population: the Hisayama Study Reviewed

Shibata M, Ninomiya T, Jensen MP, Anno K, Yonemoto K, Makino S, Iwaki R, Yamashiro K, Yoshida T, Imada Y, Kubo C, Kiyohara Y, Sudo N, Hosoi M.

PLoS One   9   e90984 - e90984   2014.3

Trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects: The Hisayama Study Reviewed

Mukai N, Doi Y, Ninomiya T, Hirakawa Y, Nagata M, Yoshida D, Hata J, Fukuhara M, Nakamura U, Kitazono T, Kiyohara Y.

J Diabetes Investig   5   162 - 169   2014.3

The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort Reviewed

Shigemizu D, Abe T, Morizono T, Johnson TA, Boroevich KA, Hirakawa Y, Ninomiya T, Kiyohara Y, Kubo M, Nakamura Y, Maeda S, Tsunoda T.

PLoS One   9   e92549 - e92549   2014.3

ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack Reviewed

Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; Fukuoka Stroke Registry Investigators.

Stroke   45   418 - 425   2014.2

Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study Reviewed

Mukai N, Yasuda M, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M, Hotta T, Koga M, Nakamura U, Kang D, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   13   45 - 45   2014.2

Cardiovascular disease in patients with chronic kidney disease Reviewed

Pilmore H, Dogra G, Roberts M, Lambers Heerspink HJ, Ninomiya T, Huxley R, Perkovic V.

Nephrology (Carlton)   19   3 - 10   2014.1

A low ankle brachial index is associated with an increased risk of cardiovascular disease: the Hisayama study Reviewed

Kojima I, Ninomiya T, Hata J, Fukuhara M, Hirakawa Y, Mukai N, Yoshida D, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   21   966 - 973   2014.1

Serum 1,25-dihydroxyvitamin d and the development of kidney dysfunction in a Japanese community Reviewed

Izumaru K, Ninomiya T, Nagata M, Usui T, Yoshida D, Yonemoto K, Fukuhara M, Tsuruya K, Kitazono T, Kiyohara Y.

Circ J   78   732 - 737   2014.1

Trends in the incidence and survival of intracerebral hemorrhage by its location in a Japanese community Reviewed

Gotoh S, Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Fukuhara M, Ikeda F, Shikata K, Kamouchi M, Kitazono T, Kiyohara Y.

Circ J   78   403 - 409   2014.1

Development and validation of a prediction rule using the Oxford classification in IgA nephropathy Reviewed

Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Noguchi H, Hirakata H, Tsuruya K, Kitazono T.

Clin J Am Soc Nephrol   8   2082 - 90   2013.12

Association between ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cardiovascular disease: the Hisayama Study Reviewed

Ninomiya T, Nagata M, Hata J, Hirakawa Y, Ozawa M, Yoshida D, Ohara T, Kishimoto H, Mukai N, Fukuhara M, Kitazono T, Kiyohara Y.

Atherosclerosis   231   261 - 267   2013.12

Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed

Ikeda F, Doi Y, Ninomiya T, Hirakawa Y, Mukai N, Hata J, Shikata K, Yoshida D, Matsumoto T, Kitazono T, Kiyohara Y.

Cardiovasc Diabetol   12   164 - 164   2013.11

Secular trends in cardiovascular disease and its risk factors in Japanese: half-century data from the Hisayama Study (1961-2009) Reviewed

Hata J, Ninomiya T, Hirakawa Y, Nagata M, Mukai N, Gotoh S, Fukuhara M, Ikeda F, Shikata K, Yoshida D, Yonemoto K, Kamouchi M, Kitazono T, Kiyohara Y.

Circulation   128   1198 - 1205   2013.9

Elevated depressive symptoms in metabolic syndrome in a general population of Japanese men: a cross-sectional study Reviewed

Sekita A, Arima H, Ninomiya T, Ohara T, Doi Y, Hirakawa Y, Fukuhara M, Hata J, Yonemoto K, Ga Y, Kitazono T, Kanba S, Kiyohara Y.

BMC Public Health   13   862 - 862   2013.9

Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study Reviewed

Nakano T, Ninomiya T, Sumiyoshi S, Onimaru M, Fujii H, Itabe H, Nakashima Y, Sueishi K, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y.

Kidney Int   84   373 - 80   2013.8

The impacts of albuminuria and low eGFR on the risk of cardiovascular death, all-cause mortality, and renal events in diabetic patients: meta-analysis Reviewed

Toyama T, Furuichi K, Ninomiya T, Shimizu M, Hara A, Iwata Y, Kaneko S, Wada T.

PLoS One   8   e71810 - e71810   2013.8

Gender differences in the association between metabolic syndrome and periodontal disease: the Hisayama Study Reviewed

Furuta M, Shimazaki Y, Takeshita T, Shibata Y, Akifusa S, Eshima N, Kiyohara Y, Ninomiya T, Hirakawa Y, Mukai N, Nagata M, Yamashita Y.

J Clin Periodontol   40   743 - 752   2013.8

Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis Reviewed

Lv J, Ehteshami P, Sarnak MJ, Tighiouart H, Jun M, Ninomiya T, Foote C, Rodgers A, Zhang H, Wang H, Strippoli GF, Perkovic V.

CMAJ   185   949 - 957   2013.8

Prediction of cardiovascular disease mortality by proteinuria and reduced kidney function: pooled analysis of 39,000 individuals from 7 cohort studies in Japan Reviewed

Nagata M, Ninomiya T, Kiyohara Y, Murakami Y, Irie F, Sairenchi T, Miura K, Okamura T, Ueshima H; EPOCH-JAPAN Research Group.

Am J Epidemiol   178   1 - 11   2013.7

White-coat and masked hypertension are associated with carotid atherosclerosis in a general population: the Hisayama study Reviewed

Fukuhara M, Arima H, Ninomiya T, Hata J, Hirakawa Y, Doi Y, Yonemoto K, Mukai N, Nagata M, Ikeda F, Matsumura K, Kitazono T, Kiyohara Y.

Stroke   44   1512 - 1517   2013.6

Temporal trends in sudden unexpected death in a general population: the Hisayama study Reviewed

Nagata M, Ninomiya T, Doi Y, Hata J, Ikeda F, Mukai N, Tsuruya K, Oda Y, Kitazono T, Kiyohara Y.

Am Heart J   165   932 - 938   2013.6

Dietary patterns and risk of dementia in an elderly Japanese population: the Hisayama Study Reviewed

Ozawa M, Ninomiya T, Ohara T, Doi Y, Uchida K, Shirota T, Yonemoto K, Kitazono T, Kiyohara Y.

Am J Clin Nutr   97   1076 - 82   2013.5

Association study of 71 European Crohn's disease susceptibility loci in a Japanese population Reviewed

Hirano A, Yamazaki K, Umeno J, Ashikawa K, Aoki M, Matsumoto T, Nakamura S, Ninomiya T, Matsui T, Hirai F, Kawaguchi T, Takazoe M, Tanaka H, Motoya S, Kiyohara Y, Kitazono T, Nakamura Y, Kamatani N, Kubo M.

Inflamm Bowel Dis   19   526 - 533   2013.3

Brachial-ankle pulse wave velocity predicts the development of cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed

Ninomiya T, Kojima I, Doi Y, Fukuhara M, Hirakawa Y, Hata J, Kitazono T, Kiyohara Y.

J Hypertens   31   477 - 83   2013.3

Angiopoietin-like protein 2 and risk of type 2 diabetes in a general Japanese population: the Hisayama study Reviewed

Doi Y, Ninomiya T, Hirakawa Y, Takahashi O, Mukai N, Hata J, Iwase M, Kitazono T, Oike Y, Kiyohara Y.

Diabetes Care   36   98 - 100   2013.1

Angiopoietin-like protein 2 is associated with chronic kidney disease in a general Japanese population: the Hisayama Study Reviewed

Usui T, Ninomiya T, Nagata M, Takahashi O, Doi Y, Hata J, Fukuhara M, Kitazono T, Oike Y, Kiyohara Y.

Circ J   77   2311 - 2317   2013.1

Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial Reviewed

Hata J, Arima H, Zoungas S, Fulcher G, Pollock C, Adams M, Watson J, Joshi R, Kengne AP, Ninomiya T, Anderson C, Woodward M, Patel A, Mancia G, Poulter N, MacMahon S, Chalmers J, Neal B; ADVANCE Collaborative Group.

PLoS One   8   e55807 - e55807   2013.1

Association study of susceptibility genes for late-onset Alzheimer's disease in the Japanese population Reviewed

Ohara T, Ninomiya T, Hirakawa Y, Ashikawa K, Monji A, Kiyohara Y, Kanba S, Kubo M.

Psychiatr Genet   22   290 - 293   2012.12

Antioxidants for chronic kidney disease Reviewed

Jun M, Venkataraman V, Razavian M, Cooper B, Zoungas S, Ninomiya T, Webster AC, Perkovic V.

Cochrane Database Syst Rev   10   CD008176 - CD008176   2012.12

Prediction of kidney-related outcomes in patients with type 2 diabetes Reviewed

Jardine MJ, Hata J, Woodward M, Perkovic V, Ninomiya T, Arima H, Zoungas S, Cass A, Patel A, Marre M, Mancia G, Mogensen CE, Poulter N, Chalmers J; ADVANCE Collaborative Group.

Am J Kidney Dis   60   770 - 778   2012.11

Association between glucose tolerance level and cancer death in a general Japanese population: the Hisayama Study Reviewed

Hirakawa Y, Ninomiya T, Mukai N, Doi Y, Hata J, Fukuhara M, Iwase M, Kitazono T, Kiyohara Y.

Am J Epidemiol   176   856 - 864   2012.11

Survival of elderly dialysis patients is predicted by both patient and practice characteristics Reviewed

Foote C, Ninomiya T, Gallagher M, Perkovic V, Cass A, McDonald SP, Jardine M.

Nephrol Dial Transplant   27   3581 - 3587   2012.9

Prevalence and risk factors for myopic retinopathy in a Japanese population: the Hisayama Study Reviewed

Asakuma T, Yasuda M, Ninomiya T, Noda Y, Arakawa S, Hashimoto S, Ohno-Matsui K, Kiyohara Y, Ishibashi T.

Ophthalmology   119   1760 - 1765   2012.9

Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study Reviewed

Ozawa M, Ninomiya T, Ohara T, Hirakawa Y, Doi Y, Hata J, Uchida K, Shirota T, Kitazono T, Kiyohara Y.

J Am Geriatr Soc   60   1515 - 1520   2012.8

Smoking cessation improves mortality in Japanese men: the Hisayama study Reviewed

Ikeda F, Ninomiya T, Doi Y, Hata J, Fukuhara M, Matsumoto T, Kiyohara Y.

Tob Control   21   416 - 21   2012.7

Putative episodes of T-cell-mediated rejection in patients with sustained BK viruria but no viremia Reviewed

Masutani K, Shapiro R, Basu A, Tan H, Ninomiya T, Randhawa P.

Transplantation   94   43 - 49   2012.7

Optimal cutoff value of the serum pepsinogen level for prediction of gastric cancer incidence: the Hisayama Study Reviewed

Shikata K, Ninomiya T, Yonemoto K, Ikeda F, Hata J, Doi Y, Fukuhara M, Matsumoto T, Iida M, Kitazono T, Kiyohara Y.

Scand J Gastroenterol   47   669 - 675   2012.6

The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis Reviewed

Jardine MJ, Kang A, Zoungas S, Navaneethan SD, Ninomiya T, Nigwekar SU, Gallagher MP, Cass A, Strippoli G, Perkovic V.

BMJ   344   e3533 - e3533   2012.6

Impact of lower range of prehypertension on cardiovascular events in a general population: the Hisayama Study Reviewed

Fukuhara M, Arima H, Ninomiya T, Hata J, Yonemoto K, Doi Y, Hirakawa Y, Matsumura K, Kitazono T, Kiyohara Y.

J Hypertens   30   893 - 900   2012.5

Dietary vitamin A intake and incidence of gastric cancer in a general Japanese population: the Hisayama Study Reviewed

Miyazaki M, Doi Y, Ikeda F, Ninomiya T, Hata J, Uchida K, Shirota T, Matsumoto T, Iida M, Kiyohara Y.

Gastric Cancer   15   162 - 169   2012.4

White blood cell count and risk of gastric cancer incidence in a general Japanese population: the Hisayama study Reviewed

Iida M, Ikeda F, Ninomiya T, Yonemoto K, Doi Y, Hata J, Matsumoto T, Iida M, Kiyohara Y.

Am J Epidemiol   175   504 - 510   2012.3

Prevalence and causes of functional disability in an elderly general population of Japanese: the Hisayama study Reviewed

Yoshida D, Ninomiya T, Doi Y, Hata J, Fukuhara M, Ikeda F, Mukai N, Kiyohara Y.

J Epidemiol   22   222 - 229   2012.1

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis Reviewed

Lv J, Neal B, Ehteshami P, Ninomiya T, Woodward M, Rodgers A, Wang H, MacMahon S, Turnbull F, Hillis G, Chalmers J, Perkovic V.

PLoS Med   9   e1001293 - e1001293   2012.1

Insulin resistance and the development of cardiovascular disease in a Japanese community: the Hisayama study Reviewed

Gotoh S, Doi Y, Hata J, Ninomiya T, Mukai N, Fukuhara M, Kamouchi M, Kitazono T, Kiyohara Y.

J Atheroscler Thromb   19   977 - 985   2012.1

N-terminal pro-brain natriuretic peptide and risk of cardiovascular events in a Japanese community: the Hisayama study Reviewed

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Ikeda F, Fukuhara M, Iwase M, Kiyohara Y.

Arterioscler Thromb Vasc Biol   31   2997 - 3003   2011.12

Validation study of oxford classification of IgA nephropathy: the significance of extracapillary proliferation Reviewed

Katafuchi R, Ninomiya T, Nagata M, Mitsuiki K, Hirakata H.

Clin J Am Soc Nephrol   6   2806 - 2813   2011.12

Midlife and late-life blood pressure and dementia in Japanese elderly: the Hisayama study Reviewed

Ninomiya T, Ohara T, Hirakawa Y, Yoshida D, Doi Y, Hata J, Kanba S, Iwaki T, Kiyohara Y.

Hypertension   58   22 - 8   2011.7

Nine-year incidence and risk factors for retinal vein occlusion in a general Japanese population: the Hisayama Study Reviewed

Arakawa S, Yasuda M, Nagata M, Ninomiya T, Hirakawa Y, Doi Y, Kiyohara Y, Ishibashi T.

Invest Ophthalmol Vis Sci   52   5905 - 9   2011.7

High serum bilirubin levels and diabetic retinopathy: the Hisayama Study Reviewed

Yasuda M, Kiyohara Y, Wang JJ, Arakawa S, Yonemoto K, Doi Y, Ninomiya T, Ishibashi T.

Ophthalmology   118   1423 - 8   2011.7

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts Reviewed

van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey A, de Jong P, Gansevoort RT; Chronic Kidney Disease Prognosis Consortium; van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey AS, de Jong PE, Gansevoort RT, Levey A, El-Nahas M, Eckardt KU, Kasiske BL, Ninomiya T, Chalmers J, Macmahon S, Tonelli M, Hemmelgarn B, Sacks F, Curhan G, Collins AJ, Li S, Chen SC, Hawaii Cohort KP, Lee BJ, Ishani A, Neaton J, Svendsen K, Mann JF, Yusuf S, Teo KK, Gao P, Nelson RG, Knowler WC, Bilo HJ, Joosten H, Kleefstra N, Groenier KH, Auguste P, Veldhuis K, Wang Y, Camarata L, Thomas B, Manley T.

Kidney Int   79   1341 - 52   2011.6

Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese: the Hisayama Study Reviewed

Ohara T, Ninomiya T, Kubo M, Hirakawa Y, Doi Y, Hata J, Iwaki T, Kanba S, Kiyohara Y.

J Am Geriatr Soc   59   1074 - 9   2011.6

Effectiveness of the salivary occult blood test as a screening method for periodontal status Reviewed

Shimazaki Y, Akifusa S, Takeshita T, Shibata Y, Doi Y, Hata J, Ninomiya T, Hirakawa Y, Kiyohara Y, Yamashita Y.

J Periodontol   82   581 - 7   2011.4

A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals Reviewed

Brugts JJ, Isaacs A, de Maat MP, Boersma E, van Duijn CM, Akkerhuis KM, Uitterlinden AG, Witteman JC, Cambien F, Ceconi C, Remme W, Bertrand M, Ninomiya T, Harrap S, Chalmers J, Macmahon S, Fox K, Ferrari R, Simoons ML, Danser AJ.

J Hypertens   29   509 - 19   2011.3

Body mass index and stroke incidence in a Japanese community: the Hisayama study Reviewed

Yonemoto K, Doi Y, Hata J, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Iida M, Kiyohara Y.

Hypertens Res   34   274 - 9   2011.2

Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese: the Hisayama study Reviewed

Hata J, Doi Y, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Hirakawa Y, Kitazono T, Kiyohara Y.

Cerebrovasc Dis   31   477 - 84   2011.1

Albuminuria as a risk factor for peripheral arterial disease in a general population: the Hisayama study Reviewed

Usui T, Ninomiya T, Nagata M, Doi Y, Hata J, Fukuhara M, Kiyohara Y.

J Atheroscler Thromb   18   705 - 12   2011.1

Circulating resistin is increased with decreasing renal function in a general Japanese population: the Hisayama Study Reviewed

Kawamura R, Doi Y, Osawa H, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Iida M, Makino H, Kiyohara Y.

Nephrol Dial Transplant   25   3236 - 40   2010.12

Severe hypoglycemia and risks of vascular events and death Reviewed

Zoungas S, Patel A, Chalmers J, de Galan BE, Li Q, Billot L, Woodward M, Ninomiya T, Neal B, MacMahon S, Grobbee DE, Kengne AP, Marre M, Heller S; ADVANCE Collaborative Group.

N Engl J Med   363   1410 - 8   2010.12

Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease Reviewed

Heerspink HJ, Ninomiya T, Perkovic V, Woodward M, Zoungas S, Cass A, Cooper M, Grobbee DE, Mancia G, Mogensen CE, Neal B, Chalmers J; ADVANCE Collaborative Group.

Eur Heart J   31   2888 - 96   2010.12

QT interval prolongation and the risks of stroke and coronary heart disease in a general Japanese population: the Hisayama study Reviewed

Maebuchi D, Arima H, Doi Y, Ninomiya T, Yonemoto K, Tanizaki Y, Kubo M, Hata J, Matsumura K, Iida M, Kiyohara Y.

Hypertens Res   33   916 - 21   2010.9

Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial Reviewed

Jardine MJ, Ninomiya T, Perkovic V, Cass A, Turnbull F, Gallagher MP, Zoungas S, Lambers Heerspink HJ, Chalmers J, Zanchetti A.

J Am Coll Cardiol   56   956 - 65   2010.9

Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population: the Hisayama Study Reviewed

Nagata M, Ninomiya T, Doi Y, Yonemoto K, Kubo M, Hata J, Tsuruya K, Iida M, Kiyohara Y.

Nephrol Dial Transplant   25   2557 - 2564   2010.8

Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease Reviewed

Brugts JJ, Isaacs A, Boersma E, van Duijn CM, Uitterlinden AG, Remme W, Bertrand M, Ninomiya T, Ceconi C, Chalmers J, MacMahon S, Fox K, Ferrari R, Witteman JC, Danser AH, Simoons ML, de Maat MP.

Eur Heart J   31   1854 - 64   2010.8

Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population Reviewed

Matsushita T, Umeno J, Hirakawa Y, Yonemoto K, Ashikawa K, Amitani H, Ninomiya T, Hata J, Doi Y, Kitazono T, Iida M, Nakamura Y, Kiyohara Y, Kubo M.

J Hum Genet   55   473 - 6   2010.7

Intensities of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis Reviewed

Jun M, Heerspink HJ, Ninomiya T, Gallagher M, Bellomo R, Myburgh J, Finfer S, Palevsky PM, Kellum JA, Perkovic V, Cass A.

Clin J Am Soc Nephrol   5   956 - 63   2010.6

Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial Reviewed

Ninomiya T, Zoungas S, Neal B, Woodward M, Patel A, Perkovic V, Cass A, Cooper M, Grobbee D, Hamet P, Harrap S, Liu L, Mancia G, Mogensen CE, Poulter N, Rodgers A, Williams B, MacMahon S, Chalmers J; ADVANCE Collaborative Group.

J Hypertens   28   1141 - 9   2010.6

The effect of metabolic syndrome defined by various criteria on the development of ischemic stroke subtypes in a general Japanese population Reviewed

Hata J, Doi Y, Ninomiya T, Tanizaki Y, Yonemoto K, Fukuhara M, Kubo M, Kitazono T, Iida M, Kiyohara Y.

Atherosclerosis   210   249 - 255   2010.5

Impact of blood pressure lowering on cardiovascular outcomes in normal weight, overweight, and obese individuals: the Perindopril Protection Against Recurrent Stroke Study trial Reviewed

Czernichow S, Ninomiya T, Huxley R, Kengne AP, Batty GD, Grobbee DE, Woodward M, Neal B, Chalmers J.

Hypertension   55   1193 - 1198   2010.5

Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke Reviewed

Matsushita T, Ashikawa K, Yonemoto K, Hirakawa Y, Hata J, Amitani H, Doi Y, Ninomiya T, Kitazono T, Ibayashi S, Iida M, Nakamura Y, Kiyohara Y, Kubo M.

Hum Mol Genet   19   1137 - 1146   2010.3

Impact of glucose tolerance status on development of ischemic stroke and coronary heart disease in a general Japanese population: the Hisayama study Reviewed

Doi Y, Ninomiya T, Hata J, Fukuhara M, Yonemoto K, Iwase M, Iida M, Kiyohara Y.

Stroke   41   203 - 209   2010.2

Association of kidney function with coronary atherosclerosis and calcification in autopsy samples from Japanese elders: the Hisayama study Reviewed

Nakano T, Ninomiya T, Sumiyoshi S, Fujii H, Doi Y, Hirakata H, Tsuruya K, Iida M, Kiyohara Y, Sueishi K.

Am J Kidney Dis   55   21 - 30   2010.1

Impact of blood pressure levels on different types of stroke: the Hisayama study Reviewed

Arima H, Tanizaki Y, Yonemoto K, Doi Y, Ninomiya T, Hata J, Fukuhara M, Matsumura K, Iida M, Kiyohara Y.

J Hypertens   27   2437 - 2443   2009.12

Development and validation of a cardiovascular risk prediction model for Japanese: the Hisayama study Reviewed

Arima H, Yonemoto K, Doi Y, Ninomiya T, Hata J, Tanizaki Y, Fukuhara M, Matsumura K, Iida M, Kiyohara Y.

Hypertens Res   32   1119 - 1122   2009.12

Impact of metabolic syndrome compared with impaired fasting glucose on the development of type 2 diabetes in a general Japanese population: the Hisayama study Reviewed

Mukai N, Doi Y, Ninomiya T, Hata J, Yonemoto K, Iwase M, Iida M, Kiyohara Y.

Diabetes Care   32   2288 - 2293   2009.12

Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial Reviewed

Zoungas S, de Galan BE, Ninomiya T, Grobbee D, Hamet P, Heller S, MacMahon S, Marre M, Neal B, Patel A, Woodward M, Chalmers J; ADVANCE Collaborative Group; Cass A, Glasziou P, Harrap S, Lisheng L, Mancia G, Pillai A, Poulter N, Perkovic V, Travert F.

Diabetes Care   32   2068 - 2074   2009.11

Diabetes and hypertension markedly increased the risk of ischemic stroke associated with high serum resistin concentration in a general Japanese population: the Hisayama Study Reviewed

Osawa H, Doi Y, Makino H, Ninomiya T, Yonemoto K, Kawamura R, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

Cardiovasc Diabetol   8   60 - 60   2009.11

Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy Reviewed

Zoungas S, Ninomiya T, Huxley R, Cass A, Jardine M, Gallagher M, Patel A, Vasheghani-Farahani A, Sadigh G, Perkovic V.

Ann Intern Med   151   631 - 638   2009.11

Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes Reviewed

Ninomiya T, Perkovic V, de Galan BE, Zoungas S, Pillai A, Jardine M, Patel A, Cass A, Neal B, Poulter N, Mogensen CE, Cooper M, Marre M, Williams B, Hamet P, Mancia G, Woodward M, Macmahon S, Chalmers J; ADVANCE Collaborative Group.

J Am Soc Nephrol   20   1813 - 1821   2009.8

The consistency of the treatment effect of an ACE-inhibitor based treatment regimen in patients with vascular disease or high risk of vascular disease: a combined analysis of individual data of ADVANCE, EUROPA, and PROGRESS trials Reviewed

Brugts JJ, Ninomiya T, Boersma E, Remme WJ, Bertrand M, Ferrari R, Fox K, MacMahon S, Chalmers J, Simoons ML.

Eur Heart J   30   1385 - 1394   2009.6

Effects of the end point adjudication process on the results of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) Reviewed

Ninomiya T, Donnan G, Anderson N, Bladin C, Chambers B, Gordon G, Sharpe N, Chalmers J, Woodward M, Neal B; PROGRESS Collaborative Group.

Stroke   40   2111 - 2115   2009.6

Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study Reviewed

Du X, Ninomiya T, de Galan B, Abadir E, Chalmers J, Pillai A, Woodward M, Cooper M, Harrap S, Hamet P, Poulter N, Lip GY, Patel A; ADVANCE Collaborative Group.

Eur Heart J   30   1128 - 1135   2009.5

Lowering blood pressure reduces renal events in type 2 diabetes Reviewed

de Galan BE, Perkovic V, Ninomiya T, Pillai A, Patel A, Cass A, Neal B, Poulter N, Harrap S, Mogensen CE, Cooper M, Marre M, Williams B, Hamet P, Mancia G, Woodward M, Glasziou P, Grobbee DE, MacMahon S, Chalmers J; ADVANCE Collaborative Group.

J Am Soc Nephrol   20   883 - 892   2009.4

Proposed criteria for metabolic syndrome in Japanese based on prospective evidence: the Hisayama study Reviewed

Doi Y, Ninomiya T, Hata J, Yonemoto K, Arima H, Kubo M, Tanizaki Y, Iwase M, Iida M, Kiyohara Y.

Stroke   40   1187 - 1194   2009.4

Lack of association between variations of PDE4D and ischemic stroke in the Japanese population Reviewed

Matsushita T, Kubo M, Yonemoto K, Ninomiya T, Ashikawa K, Liang B, Hata J, Doi Y, Kitazono T, Ibayashi S, Iida M, Kiyohara Y, Nakamura Y.

Stroke   40   1245 - 1251   2009.4

Hyperglycemia increases risk of gastric cancer posed by Helicobacter pylori infection: a population-based cohort study Reviewed

Ikeda F, Doi Y, Yonemoto K, Ninomiya T, Kubo M, Shikata K, Hata J, Tanizaki Y, Matsumoto T, Iida M, Kiyohara Y.

Gastroenterology   136   1234 - 1241   2009.4

Proteinuria and stroke: a meta-analysis of cohort studies Reviewed

Ninomiya T, Perkovic V, Verdon C, Barzi F, Cass A, Gallagher M, Jardine M, Anderson C, Chalmers J, Craig JC, Huxley R.

Am J Kidney Dis   53   417 - 425   2009.3

Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials Reviewed

Heerspink HJ, Ninomiya T, Zoungas S, de Zeeuw D, Grobbee DE, Jardine MJ, Gallagher M, Roberts MA, Cass A, Neal B, Perkovic V.

Lancet   373   1009 - 1015   2009.3

Seroprevalence of herpes simplex virus 1 and 2 in a population-based cohort in Japan Reviewed

Doi Y, Ninomiya T, Hata J, Yonemoto K, Tanizaki Y, Arima H, Liu Y, Rahman M, Iida M, Kiyohara Y.

J Epidemiol   19   56 - 62   2009.1

The improvement of renal survival with steroid pulse therapy in IgA nephropathy Reviewed

Katafuchi R, Ninomiya T, Mizumasa T, Ikeda K, Kumagai H, Nagata M, Hirakata H.

Nephrol Dial Transplant   23   3915 - 3920   2008.12

Impact of kidney disease and blood pressure on the development of cardiovascular disease: an overview from the Japan Arteriosclerosis Longitudinal Study Reviewed

Ninomiya T, Kiyohara Y, Tokuda Y, Doi Y, Arima H, Harada A, Ohashi Y, Ueshima H; Japan Arteriosclerosis Longitudinal Study Group.

Circulation   118   2694 - 2701   2008.12

Population-based prospective study of the combined influence of cigarette smoking and Helicobacter pylori infection on gastric cancer incidence: the Hisayama Study Reviewed

Shikata K, Doi Y, Yonemoto K, Arima H, Ninomiya T, Kubo M, Tanizaki Y, Matsumoto T, Iida M, Kiyohara Y.

Am J Epidemiol   168   1409 - 1415   2008.12

The relationship between proteinuria and coronary risk: a systematic review and meta-analysis Reviewed

Perkovic V, Verdon C, Ninomiya T, Barzi F, Cass A, Patel A, Jardine M, Gallagher M, Turnbull F, Chalmers J, Craig J, Huxley R.

PLoS Med   5   e207 - e207   2008.12

Do men and women respond differently to blood pressure-lowering treatment? Results of prospectively designed overviews of randomized trials Reviewed

Turnbull F, Woodward M, Neal B, Barzi F, Ninomiya T, Chalmers J, Perkovic V, Li N, MacMahon S; Blood Pressure Lowering Treatment Trialists' Collaboration.

Eur Heart J   29   2669 - 2680   2008.11

Fasting plasma glucose cutoff for diagnosis of diabetes in a Japanese population Reviewed

Doi Y, Kubo M, Yonemoto K, Ninomiya T, Iwase M, Arima H, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

J Clin Endocrinol Metab   93   3425 - 3429   2008.9

Efficacy and safety of fixed combination of perindopril and indapamide in type 2 diabetes: results from ADVANCE in context of available evidence Reviewed

Chalmers J, Joshi R, Kengne AP, Ninomiya T, Bi Y, Bompoint S, Billot L, Patel A; ADVANCE Collaborative Group.

J Hypertens Suppl   26   S21 - S27   2008.9

High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese: the Hisayama study Reviewed

Arima H, Kubo M, Yonemoto K, Doi Y, Ninomiya T, Tanizaki Y, Hata J, Matsumura K, Iida M, Kiyohara Y.

Arterioscler Thromb Vasc Biol   28   1385 - 1391   2008.7

Arterial stiffness and QT interval prolongation in a general population: the Hisayama study Reviewed

Maebuchi D, Arima H, Ninomiya T, Yonemoto K, Kubo M, Doi Y, Tanizaki Y, Matsumura K, Iida M, Kiyohara Y.

Hypertens Res   31   1339 - 1345   2008.7

Impact of serum total cholesterol on the incidence of gastric cancer in a population-based prospective study: the Hisayama study Reviewed

Asano K, Kubo M, Yonemoto K, Doi Y, Ninomiya T, Tanizaki Y, Arima H, Shirota T, Matsumoto T, Iida M, Kiyohara Y.

Int J Cancer   122   909 - 914   2008.2

Polymorphisms in the lymphotoxin alpha gene and the risk of ischemic stroke in the Japanese population. The Fukuoka Stroke Registry and the Hisayama Study Reviewed

Hagiwara N, Kitazono T, Kamouchi M, Kuroda J, Ago T, Hata J, Ninomiya T, Ooboshi H, Kumai Y, Yoshimura S, Tamaki K, Fujii K, Nagao T, Okada Y, Toyoda K, Nakane H, Sugimori H, Yamashita Y, Wakugawa Y, Kubo M, Tanizaki Y, Kiyohara Y, Ibayashi S, Iida M.

Cerebrovasc Dis   25   417 - 422   2008.1

Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS study Reviewed

Perkovic V, Ninomiya T, Arima H, Gallagher M, Jardine M, Cass A, Neal B, Macmahon S, Chalmers J.

J Am Soc Nephrol   18   2766 - 2772   2007.12

Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study Reviewed

Doi Y, Kubo M, Ninomiya T, Yonemoto K, Iwase M, Arima H, Hata J, Tanizaki Y, Iida M, Kiyohara Y.

Diabetes   56   2829 - 2833   2007.11

Impact of metabolic syndrome on the development of cardiovascular disease in a general Japanese population: the Hisayama study Reviewed

Ninomiya T, Kubo M, Doi Y, Yonemoto K, Tanizaki Y, Rahman M, Arima H, Tsuryuya K, Iida M, Kiyohara Y.

Stroke   38   2063 - 2069   2007.7

Liver enzymes as a predictor for incident diabetes in a Japanese population: the Hisayama study Reviewed

Doi Y, Kubo M, Yonemoto K, Ninomiya T, Iwase M, Tanizaki Y, Shikata K, Iida M, Kiyohara Y.

Obesity (Silver Spring)   15   1841 - 1850   2007.7

Prehypertension increases the risk for renal arteriosclerosis in autopsies: the Hisayama Study Reviewed

Ninomiya T, Kubo M, Doi Y, Yonemoto K, Tanizaki Y, Tsuruya K, Sueishi K, Tsuneyoshi M, Iida M, Kiyohara Y.

J Am Soc Nephrol   18   2135 - 2142   2007.7

Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction Reviewed

Hata J, Matsuda K, Ninomiya T, Yonemoto K, Matsushita T, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Iida M, Kiyohara Y, Nakamura Y, Kubo M.

Hum Mol Genet   16   630 - 639   2007.3

A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction Reviewed

Kubo M, Hata J, Ninomiya T, Matsuda K, Yonemoto K, Nakano T, Matsushita T, Yamazaki K, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Sueishi K, Iida M, Nakamura Y, Kiyohara Y.

Nat Genet   39   212 - 217   2007.2

Metabolic syndrome and CKD in a general Japanese population: the Hisayama Study Reviewed

Ninomiya T, Kiyohara Y, Kubo M, Yonemoto K, Tanizaki Y, Doi Y, Hirakata H, Iida M.

Am J Kidney Dis   48   383 - 391   2006.9

A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: the Hisayama study Reviewed

Shikata K, Kiyohara Y, Kubo M, Yonemoto K, Ninomiya T, Shirota T, Tanizaki Y, Doi Y, Tanaka K, Oishi Y, Matsumoto T, Iida M.

Int J Cancer   119   196 - 201   2006.7

The serum pepsinogen test as a predictor of gastric cancer: the Hisayama study Reviewed

Oishi Y, Kiyohara Y, Kubo M, Tanaka K, Tanizaki Y, Ninomiya T, Doi Y, Shikata K, Yonemoto K, Shirota T, Matsumoto T, Iida M.

Am J Epidemiol   163   629 - 637   2006.4

C-reactive protein and risk of first-ever ischemic and hemorrhagic stroke in a general Japanese population: the Hisayama Study Reviewed

Wakugawa Y, Kiyohara Y, Tanizaki Y, Kubo M, Ninomiya T, Hata J, Doi Y, Okubo K, Oishi Y, Shikata K, Yonemoto K, Maebuchi D, Ibayashi S, Iida M.

Stroke   37   27 - 32   2006.1

Elevated C-reactive protein is a predictor of the development of diabetes in a general Japanese population: the Hisayama Study Reviewed

Doi Y, Kiyohara Y, Kubo M, Ninomiya T, Wakugawa Y, Yonemoto K, Iwase M, Iida M.

Diabetes Care   28   2497 - 2500   2005.12

Chronic kidney disease and cardiovascular disease in a general Japanese population: the Hisayama Study Reviewed

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Doi Y, Okubo K, Wakugawa Y, Hata J, Oishi Y, Shikata K, Yonemoto K, Hirakata H, Iida M.

Kidney Int   68   228 - 236   2005.7

Secular trends in the incidence, mortality, and survival rate of gastric cancer in a general Japanese population: the Hisayama study Reviewed

Tanaka K, Kiyohara Y, Kubo M, Matsumoto T, Tanizaki Y, Okubo K, Ninomiya T, Oishi Y, Shikata K, Iida M.

Cancer Causes Control   16   573 - 578   2005.6

Relationship between C-reactive protein and glucose levels in community-dwelling subjects without diabetes: the Hisayama Study Reviewed

Doi Y, Kiyohara Y, Kubo M, Tanizaki Y, Okubo K, Ninomiya T, Iwase M, Iida M.

Diabetes Care   28   1211 - 1213   2005.5

Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama study Reviewed

Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Tanaka K, Okubo K, Nakamura H, Hata J, Oishi Y, Kato I, Hirakata H, Iida M.

Am J Kidney Dis   44   437 - 445   2004.9

Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways Reviewed

Tsuruya K, Tokumoto M, Ninomiya T, Hirakawa M, Masutani K, Taniguchi M, Fukuda K, Kanai H, Hirakata H, Iida M.

Am J Physiol Renal Physiol   285   F208 - F218   2003.8

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death Reviewed

Tsuruya K, Ninomiya T, Tokumoto M, Hirakawa M, Masutani K, Taniguchi M, Fukuda K, Kanai H, Kishihara K, Hirakata H, Iida M.

Kidney Int   63   72 - 82   2003.1

Myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis superimposed on biopsy-proven diabetic nephrosclerosis Reviewed

Ninomiya T, Kanai H, Hirakawa M, Arimura Y, Masutani K, Kashiwagi M, Nakamura S, Koga Y, Fukuda K, Hirakata H.

Am J Kidney Dis   39   E4 - E4   2002.1

Chapter2. Epidemiological evidence of the relationship between diabetes and dementia. Diabetes Mellitus A risk factor for Alzheimer's Disease, Nakabeppu Y, Ninomiya T(Editors),

Ninomiya T（Role：Joint author）

Springer  2019.8 

Chapter6. Epidemiology of dementia in a community: the Hisayama Study.

Ninomiya T

Health Issues and Care System for the Elderly, Washio M, Kiyohara C(editors),Springer  2019.2 

Diet and nutrition in dementia and cognitive decline: Japanese perspective on dietary patterns and risk of dementia

Ninomiya T, Ozawa M（Role：Joint author）

2015.1 

Brain, Stroke and Kidney (Contributions to Nephrology, Vol. 179): Risk of stroke in kidney disease

Ninomiya T（Role：Sole author）

2013.1 

慢性腎臓病における心血管疾患. 4）脳卒中. 心腎相関の病態理解と診療.

永田　雅治, 二宮　利治, 清原　裕,（Role：Edit）

2008.1 

心血管病変：慢性腎機能障害における心血管病発症.

二宮　利治, 平方　秀樹, 清原　裕.（Role：Edit）

2006.1 

第1章 高血圧症の概念･定義 疫学 －日本人の高血圧症の特徴－.

二宮　利治, 清原　裕.（Role：Edit）

2004.1 

日本におけるCKDの疫学. 慢性腎臓病と心血管病：久山町研究及びJALS統合研究. Invited

二宮　利治, 清原　裕.

第52回日本腎臓学会学術総会.  2009.6 

The fixed combination of perindopril and indapamide has a greater effect on cardiovascular outcomes in patients with type 2 diabetes and albuminuria. International conference

Ninomiya T, Heerspink HJL, Perkovic V, Zoungas S, Patel A, Grobbee D, Harrap S, Heller S, Cooper M, MacMahon S, Mancia G, Marre M, Neal B, Woodward M, Chalmers J.

ISN Nexus Symposium Kyoto 2010  2010.4 

認知機能における25-OHビタミンDの関連：海士町研究．<ポスター>

古和久典、深田育代、中野俊也、岸　真文、和田健二、二宮利治、中島健二

第42回日本認知症学会学術集会  2024.11 

地域住民を対象とした認知症の疫学研究<講義>

二宮利治

第一薬科大学看護学部講義  2024.11  第一薬科大 看護学部

地域住民を対象とした認知症の疫学研究．

二宮利治

第一薬科大学看護学部講義  2024.11 

地域高齢住民における歯数とサルコペニア発症との関連：久山町研究．

友岡祥子、柏﨑晴彦、二宮利治

日本老年歯科医学会第35回学術大会  2024.6 

生活習慣と認知症．

二宮利治

若宮シニアクラブ第3回健康づくりセミナー  2024.6 

<シンポジウム30>老年医学における大規模データベースの活用．

<座長> 寳澤　篤、二宮利治

第66回日本老年医学会学術集会  2024.6 

地域認知症コホート研究の推進：久山町研究とJPSC-AD研究<シンポジウム30>老年医学における大規模データベースの活用．

二宮利治

第66回日本老年医学会学術集会  2024.6 

地域循環器コホート研究からの最近知見<会長特別企画2>九州の循環器コホートからの情報発信．

二宮利治

第136回日本循環器学会九州地方会  2024.6 

地域認知症コホート研究：久山町研究における最近の知見<会長企画シンポジウム1>コホート研究から健康長寿の鍵を紐解く．

二宮利治

第24回日本抗加齢医学会総会  2024.5 

地域疫学研究の実際．

二宮利治

九州大学大学院医療経営・管理学専攻講義  2024.5 

食事と運動機能が認知症発症リスクに及ぼす影響：久山町研究．

二宮利治

第78回日本栄養・食糧学会大会  2024.5 

地域認知症コホート研究の最近知見：久山町研究．

二宮利治

第25回九州老年期認知症研究会（Web講演会）  2024.5 

心電図P波指標と心房細動発症、組織的線維化との関連：久山町研究．

二宮利治

COI-NEXT第26回弘前大学健康未来イノベーション研究機構運営会議（健康未来共創会議）  2024.5 

血清asngiopoietin-like protein 2 (ANGPTL2)濃度と死因別死亡の関連：久山町研究．

秦　淳、坂田智子、古田芳彦、大石絵美、本田貴紀、柴田舞欧、北園孝成、尾池雄一、二宮利治

第60回日本循環器病予防学会学術集会  2024.5 

<シンポジウム1>古くて新しい循環器疾患のマーカー．

二宮利治

第60回日本循環器病予防学会学術集会  2024.5  日本循環器予防学会学術集会

地域住民を対象とした認知症の疫学調査．

二宮利治

九州大学歯学部歯科全身管理学特別講義  2024.5 

バイオバンクとデータ解析のワークショップ．

二宮利治

Tokyo Symposium & Workshop on Genomic Medicine, Therapeutics and Health、  2024.4 

研究デザインや基本的な統計解析の手法について学ぼう．

二宮利治

第6回初学者のためのCKD臨床研究セミナー＠九州大学  2024.3 

地域住民における角膜ヒステリシスと緑内障の関連：久山町研究．

藤原康太、上田瑛美、橋本左和子、中村　駿、秦　淳、中野聡子、村上祐介、久保田敏昭、吉冨健志、二宮利治、園田康平

第127回日本眼科学会総会  2023.4 

地域住民における高血圧の有病率・管理状況および心血管病発症リスクの時代的推移：久山町研究．

秦　淳、大石絵美、二宮利治

第45回日本高血圧学会総会  2023.9 

血漿認知症バイオマーカーと認知症発症の関係：地域前向きコホート研究の成績より．

小原知之、秦　淳、徳田隆彦、本田貴紀、柴田舞欧、中路重之、前田哲也、小野賢二郎、三村　將、中島健二、伊賀淳一、竹林　実、二宮利治

第38回日本老年精神医学会秋季大会  2023.10 

疫学．

二宮利治

令和健康科学大学講義  2023.11 

認知症の血漿バイオマーカーと認知症発症との関連<シンポジウム15>認知症バイオマーカー研究の最新知見．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

地域疫学研究を基盤とした脳梗塞発症のリスク予測：久山町研究<シンポジウム9>データベース研究の新展開．

秦　淳、二宮利治

第66回日本脳循環代謝学会学術集会  2023.11 

久山町コホートからみた生活習慣病・生活習慣と脳画像との関連<シンポジウム3>地域コホート研究からみた生活習慣・生活習慣病と脳画像との関連．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

古和久典、深田育代、中野俊也、岸　真文、和田健二、二宮利治、中島健二

認知機能における25-CHビタミンDの関連：海士町研究．<ポスター>

第42回日本認知症学会学術集会  2023.11 

陳　俐穎、舘脇康子、Benjamin Thyreau、内田和宏、壹岐ひかり、中瀬泰然、中路重之、前田哲也、野口・篠原もえ子、三村　將、中島健二、伊賀淳一、竹林　実、二宮利治、瀧　靖之

白質病変の定量化による日本人大規模高齢者集団の食事パターンと認知症に関する研究．<ポスター>

第42回日本認知症学会学術集会  2023.11 

水野裕理、本田裕之、二宮利治、磯部紀子、村井弘之

アルツハイマー型認知症の脳内におけるトランスサイレチンの発現様式の検討．<ポスター>

第42回日本認知症学会学術集会  2023.11 

地域高齢住民における認知症有病率の時代的変化：久山町研究．

小原知之、二宮利治

第42回日本認知症学会学術集会  2023.11 

地域住民における尿中神経伝達物質と抑うつ症状発症の関連：久山町研究．<ポスター>

柴田舞欧、平林直樹、細井昌子、中村侑里、秦　淳、須藤信行、二宮利治

第27回日本心療内科学会総会・学術大会  2023.12 

動脈硬化性疾患の疫学研究：久山町研究の最近の知見より．

二宮利治

第45回福岡東脳卒中の地域連携の夕べ  2024.2 

地域糖尿病コホート研究・久山町研究．

二宮利治

糖尿病治療を考える会、福岡市、2024.2  2024.2 

地域高齢者住民を対象とした大規模認知症コホート研究（JPSC-AD研究）の取組．

二宮利治

第2回医療・健康ユニットシンポジウム  2024.3 

認知症予防における筋力・運動機能維持の重要性．

二宮利治

平尾公民館平尾大学  2024.3 

日本人地域住民における座位行動と糖代謝マーカーの経時変化および糖尿病発症の関連：久山町研究． International conference

津田　晋、本田貴紀、東岡真由、秦　淳、中野敏昭、北園孝成、二宮利治

第34回日本疫学会学術総会  2024.2 

地域住民における健康管理への取組～久山町研究～．

二宮利治

Oriental land Friendship Society九州研修  2024.1 

久山町研究からの最近の知見．

二宮利治

NCVC Seminar Series  2024.1 

全国の一般地域住民における最近の循環器疾患発症率．<ポスター>

門田　文、大久保孝義、原田亜紀子、高嶋直敬、有馬久富、二宮利治、秦　淳、寶澤　篤、中村幸志、東山　綾、大澤正樹、久松隆史、鳥居さゆ希、岡見雪子、近藤慶子、宮本恵宏、岡村智教、上島弘嗣、岡山　明、三浦克之

第34回日本疫学会学術総嶋  2024.2 

地域住民における社会的・情緒的孤独感と慢性疼痛の関連：久山町研究．

柴田舞欧、平林直樹、細井昌子、安野広三、秦　淳、須藤信行、二宮利治

第30回日本未病学会学術総会  2023.12 

日本人地域住民における教育年数と眼軸長および開放隅角緑内障の関連：久山町研究．

中村　駿、上田瑛美、藤原康太、柴田舞欧、安田美穂、本田貴紀、橋本左和子、秦　淳、二宮利治、園田康平

第5回日本近視学会総会  2023.5 

臨床・疫学研究の進め方．

二宮利治

岩手医科大学 講演会  2023.12 

大規模認知症コホート研究（JPSC-AD）について．

二宮利治

やはば脳とカラダのいきいき健康事業、いきいき記念講演会2023  2023.12 

高齢者保健．

二宮利治

令和健康科学大学講義  2023.12 

感染症．

二宮利治

令和健康科学大学講義  2023.12 

認知症発症のリスク低減における生活習慣病予防および運動機能維持の重要性：久山町研究．<特別講演>

二宮利治

大牟田臨床認知症研究会第34回特別講演会  2023.12 

久山町研究のこれから<記念シンポジウム>久山町研究の過去、未来．

二宮利治

九州大学医学部120周年を祝う会  2023.12 

日本人地域住民におけるサルコペニアの疫学：久山町研究<シンポジウム9>筋肉・サルコペニア肥満．

秦　淳、二宮利治

第44回日本肥満学会・第41回日本肥満症治療学会学術集会  2023.11 

動脈硬化性疾患のリスク評価：久山町研究．

二宮利治

宗像内科医会学術講演会  2023.9 

日本人地域住民における血清NT-proBNPの変化と慢性腎臓病発症との関連：久山町研究．

大石絵美、坂田智子、秦　淳、北園孝成、二宮利治

第45回日本高血圧学会総会  2023.9 

日本人一般集団における血圧の日間変動と慢性腎臓病発症リスク

佐々木峻也、坂田智子、大石絵美、秦　淳、坪井伸夫、北園孝成、横尾　隆、二宮利治

第45回日本高血圧学会総会、大阪市、2023.9  2023.8 

白衣高血圧は心血管病発症の危険因子となるか？：久山町研究．

坂田智子、大石絵美、秦　淳、北園孝成、二宮利治

第45回日本高血圧学会総会  2023.9 

1機会に測定した1回目と2回目の家庭血圧値の変化に影響する因子の検討：福岡高血圧コホート（FHC）研究．

寒水康雄、松村　潔、大森　将、坂田智子、大坪俊夫、冨永光裕、鍵山俊太郎、川﨑純也、赤崎　卓、藤島八重、阿部　功、二宮利治、後藤健一、𡈽橋卓也、北園孝成

第45回日本高血圧学会総会  2023.9 

<ランチョンセミナー5>認知症発症のリスク低減における生活習慣病予防および運動機能維持の重要性：久山町研究．

二宮利治

第12回日本認知症予防学会学術集会  2023.9 

Association of impaired olfactory identification with prevalent mild cognitive impairment and regional brain atrophy:the Hisayama Study.<poster> International conference

Minohara T, Ohara T, Nakazawa T, Hirabayashi N, Hata J, Furuta Y, Mihara A, Shibata M, Kitazono T, Nakao T, Ninomiya T

23rd WPA World Congress of Psychiatry, Vienna, Austria, 2023.9  2023.9 

認知症・要介護予防におけるロコモ・フレイル対策の重要性：久山町研究の成績より．

二宮利治

第4回元気100倶楽部健康長寿フェア2023  2023.10 

日本人地域高齢住民における網膜症と認知症発症との関連：久山町研究．

中村　駿、上田瑛美、小原知之、秦　淳、本田貴紀、藤原康太、古田芳彦、柴田舞欧、橋本左和子、中澤太郎、中尾智博、北園孝成、園田康平、二宮利治

第77回日本臨床眼科学会  2023.10 

<特別企画4>包括的RWD構築（データ連携）最前線.

二宮利治

弘前大学COI-NEXT Well-being イノベーションフォーラム2023  2023.10 

地域住民を対象とした認知症の疫学研究．

二宮利治

第一薬科大学看護学部講義  2023.10 

<ランチョンセミナー>地域住民における動脈硬化性疾患の疫学研究－久山町研究－．

二宮利治

第63回日本臨床化学会年次学術集会  2023.10 

認知症予防における筋力・運動機能維持の重要性．

二宮利治

九州市民大学令和5年度「秋の集中講義」  2023.10