|Hiroyuki Sasaki||Last modified date：2020.07.17|
Dean of the Institute for Advanced Study
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Reseacher Profiling Tool Kyushu University Pure
Doctor of Medical Science (MD, PhD)
Country of degree conferring institution (Overseas)
Field of Specialization
Molecular Biology, Human Genetics
Total Priod of education and research career in the foreign country
Sasaki's research interest is epigenetics and epigenomics in mammals. Epigenetics refers to the regulation of gene activity based on modifications of chromatin: it stably maintains cellular identity (differentiation state) and serves as a cell memory. The epigenetic profile of a cell is called the epigenome, and characterization of the epigenomes of various cells and their regulation is thought to be the key to understanding of cell reprogramming and cancer formation. Sasaki investigates the regulatory mechanisms of the epigenome in mammals and their relevance to development, disease, phenotypic variation and evolution. He particularly focuses on genomic imprinting, which is a good model system to study epigenomic regulation in mammals. He was a program leader of a Grant-in Aid for Scientific Research on Priority Areas supported by the MEXT (2007-2012) and a PI of a CREST project supported by the JST and AMED (2013-2018). He now leads a Specially Promoted Research supported by JSPS (2018-). Sasaki teaches molecular biology, genetics, and epigenetics and supervise many graduate students. He was on newspapers and TV programs many times. He was awarded a Japanese Society of Human Genetics Award and a Japanese Society of Genetics Kihara Award. He also received a Purple Ribbon Medal of honor in 2015.
Research InterestsMembership in Academic Society
- Epigenomics in Mammals
keyword : epigenetics、genomic imprinting、small RNA
- Grant-in-Aid for Scientific Research on Innovative Areas by MEXT, 2013.7~2018.3
- The Japanese Society for Epigenetics
- The Japan Society of Human Genetics
- The Molecular Biology Society of Japan
- The Genetics Society of Japan
- Japan Society for Reproductive Regeneration
- Society of Evolutionary Studies, Japan
I give lectures for classes of the Graduate School of Medical Sciences and serve as a thesis adviser for master and doctor course students. I also give lectures for undergraduate classes of the Department of Biomedical Science, School of Medicine, and serve as a thesis adviser for students who work for a bachelor degree. Outside of Kyushu University, I gave lectures as an adjunct professor or a part-time lecturer in the following institutions: Graduate University for Advanced Studies, University of Tokyo, Kyoto University, Osaka University , Hokkaido University, Tokyo Institute of Technology, Ochanomizu University, Kanazawa University, Yamanashi University, Shizuoka University, Nara Institute of Science and Technology, Shimane University, Tokushima University, University of Occupational and Environmental Health, Kumamoto University, Kagoshima University, Gunma University, Yokohama City University, Kitasato University, and Sojo University.