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Hiroko Wada Last modified date：2022.11.09

Assistant Professor / Laboratory of Oral Pathology
Department of Dental Science
Faculty of Dental Science


Graduate School
Department of Dental Science
Graduate School of Dental Science
Undergraduate School
Department of Dentistry
School of Dentistry


E-Mail　*Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
Homepage
https://kyushu-u.pure.elsevier.com/en/persons/hiroko-wada
　Reseacher Profiling Tool　Kyushu University Pure
http://www.dent.kyushu-u.ac.jp/koza/koku_gaku_ganmen/koku_gaku_ganmen_byoutai/kenkyugaiyo.html
Section of Oral Pathology and Medicine (Kyushu University) .
Phone
092-642-6326
Fax
092-642-6329
Academic Degree
Doctor of Dentistry
Field of Specialization
Oral Pathology
Research
Research Interests
  • Mechanism of tooth development based on mechanical sensor
    keyword : mechanical sensor tooth development regeneration
    2015.04.
  • The study of
    keyword : oral cancer, specific gene
    2010.04.
  • Study of dental regeneration
    keyword : dental development regeneration
    1999.04.
  • The study of
    keyword : statin, regeneration of alveolar bone, implant
    2003.04～2007.04.
  • The present situation and needs of oral care in nursing homes and facilities of health care service for elderly in Kyushu
    keyword : Special nursing home, Facilities of health care service for elderly, Oral care
    1997.06～1999.03.
Academic Activities
Papers
 Show All Papers >>
1. Fujii S, Fujimoto T, Hasegawa K, Nagano R, Ishibashi T, Kurppa KJ, Mikami Y, Kokura M, Tajiri Y, Kibe T, Wada H, Wada N, Kishida S, Higuchi Y, Kiyoshima T., The Semaphorin 3A-AKT axis-mediated cell proliferation in salivary gland morphogenesis and adenoid cystic carcinoma pathogenesis.
, Pathol Res Pract., 10.1016/j.prp.2022.153991, 236, 153991, 2022.08.
2. Matsunaka K, Imai M, Sanda K, Yasunami N, Furuhashi A, Atsuta I, Wada H, Ayukawa Y., Therapeutic Effect of Benidipine on Medication-Related Osteonecrosis of the Jaw., Pharmaceuticals (Basel), 10.3390/ph15081020., 15, 8, 1020, 2022.08.
3. Haraguchi A , Yoshida S, Takeshita M, Sumi Y, Mitarai H, Yuda A, Wada H, Nishimura F, Maeda H, Wada N., Effects of ultraviolet irradiation equipment on endodontic disease–related bacteria, Lasers in Dental Science, doi.org/10.1007/s41547-021-00145-8, 6, 31-40, 2022.01, [URL].
4. J Yoshizumi, H Wada, M Shimizu, Y Horinouchi, T Kiyoshima, T Ikebe, A Hiraki., A rare case of cemento-osseous dysplasia arising from a dislocated impacted tooth in the maxillary sinus, Journal of Oral and Maxillofacial Surgery, Medicine and Pathology, 31, 2, 94-97, 2018.08.
5. Matsuishi Y, Kato H, Yamaza H, Hirofuji Y, Sato H, Wada H, Kiyoshima T, Nonaka K., Accelerated dentinogenesis by inhibiting the mitochondrial fission factor, dynamin related protein 1, Biochem Biophys Res Commun., 10.1016/j.bbrc.2017.12.026., 8;495(2):1655-1660., 495(2), 1655-1660, 2018.01.
6. Yurie Mikami, Fujii Shinsuke, Kengo Nagata, Hiroko Wada, Kana Hasegawa, Tamotsu Kiyoshima, Misaki Abe, Reiko Yoshimoto, Shintaro Kawano, Seiji Nakamura, GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas , J Cancer Res Clin Oncol., 10.1007/s00432-017-2398-2, 2017.03.
7. Kana Hasegawa, Hiroko Wada, Kengo Nagata, Hiroaki　Fujiwara, Naohisa Wada, Hirotaka Someya, Yurie Mikami, Sakai Hidetaka, Tamotsu Kiyoshima, Facioscapulohumeral Muscular Dystrophy (FSHD) Region Gene 1 (FRG1) Expression and Possible Function in Mouse Tooth Germ Development, Journal of Molecular Histology, 2016.06.
8. S Fadhillah, O Mattalitti, Toshiyuki Kawadu, Shintaro Kawano, TATSUYA IKARI, Hiroko Wada, 吉浦 一紀, Estimation of prognosis of tongue cancer using tumor depth and margin shape obtained from ultrasonography., Oral radiol., 2016.06.
9. Someya H, Fujiwara H, Nagata K, Wada H, Hasegawa K, Mikami Y, Jinno A, Sakai H, kiyoshi k, Kiyoshima T, Thymosin beta 4 is associated with RUNX2 expression via the Smad and Akt signaling pathways in mouse dental epithelial cells., Int. J. Mol. Med., DOI: 10.3892, 2015.01.
10. Kihara M, Kiyoshima T, Nagata K, Wada H, Fujiwara H, Hasegawa K, Someya H, Takahashi I, Sakai H, Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells., PLoS One, doi:10.1371/journal.pone.0103928, 9(7), 2014.07.
11. Kiyoshima T, Fujiwara H, Nagata K, Wada H, Ookuma Y, Shiotsuka M, Kihara M, Hasegawa K, Someya H, Sakai H, Induction of dental epithelial cell differentiation marker gene expression in non-odontogenic human keratinocytes by transfection with thymosin beta 4., Stem Cell Res., 10.1016/j.scr.2013.11.006, 12(1), 309-322, 2014.01.
12. Shiotsuka M*, Wada H*, Kiyoshima T*, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H, Takahashi I, Sakai H. * equally to contributed, The Expression and Function of Thymosin beta 10 in the Tooth Germ Development., Int. J. Dev. Biol., 10.1387/ijdb.120240hs., 57(11-12), 873-883, 2013.12.
13. Kiyoshima T, Yoshida H, Wada H, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H, Sakai H, Chemoresistance to Concanamycin A1 in Human Oral Squamous Cell Carcinoma Is Attenuated by an HDAC Inhibitor Partly via Suppression of Bcl-2 Expression, PLoS One, 10.1371/journal.pone.0080998, 8(11), e80998, 2013.11.
14. Kiyoshima T, Nagata K, Wada H, Fujiwara H, Shiotsuka M, Kihara M, Hasegawa K, Someya H, Sakai H, Immunohistochemical Expression of Thymosin β 4 in Ameloblastomas and odontomas., Histol. Histopathol., 28(6), 775-786, 2013.06.
15. Ookuma Y, Kiyoshima T, Kobayashi I, Nagata K, Wada H, Fujiwara H, Yamaza H, Nonaka K, Sakai H, Multiple functional involvement of Thymosin beta-4 in Tooth Germ Development., Histochem. Cell Biol., 10.1007/s00418-012-1033-1., 139(2), 355-370, 2013.02.
16. Kiyoshima T, Enoki N, Kobayashi I, Sakai T, Nagata K, Wada H, Fujiwara H, Ookuma Y, Sakai H, Oxidative stress caused by a low concentration of hydrogen peroxide induces senescence-like changes in mouse gingival fibroblasts., Int. J. Mol. Med., 10.3892/ijmm.2012.1102., 30(5), 1007-1012, 2012.09.
17. Naher L, Kiyoshima T, Kobayashi I, Wada H, Nagata K, Fujiwara H, Ookuma Y, Ozeki S, Nakamura S, Sakai H, STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma., Int. J. Oncol., 10.3892/ijo.2012., 41(5), 1577-1586, 2012.07.
18. Honda JY, Kobayashi I, Kiyoshima T, Nagata K, Wada H, Ookuma Y, Fujiwara H, Shiotsuka M, Takahashi I, Sakai H., In situ expression of the mitochondral ATPase6 gene in the developing tooth germ of the mouse lower first molar., J Mol Histol., 42, 1, 83-90, 2011.02.
19. Takahashi KF, Kiyoshima T, Kobayashi I, Xie M, Yamaza H, Fujiwara H, Ookuma Y, Nagata K, Wada H, Sakai T, Terada Y, Sakai H., Protogenin, a new member of the immunoglobulin superfamily, is implicated in the development of the mouse lower first molar., BMC Dev Biol., 10, 115, 2010.11.
20. Akhter M, Kobayashi I, Kiyoshima T, Nagata K, Wada H, Ookuma Y, Fujiwara H, Honda JY, Sakai H., In situ expression of 15kDa interferon alpha responsive gene in the developing tooth germ of the mouse lower first molar., J Mol Histol., 41, 4-5, 185-91, 2010.07.
21. Ayukawa Y, Yasukawa E, Moriyama Y, Ogino Y, Wada H, Atsuta I, Koyano K, Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats., Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 107(3): 336-342, 2009, 107(3): 336-342, 2009, 2009.03.
22. Kobayashi I, Kiyoshima T, Wada H, Matsuo K, Nonaka K, Honda JY, Koyano K, Sakai H., Type II/III Runx2/Cbfa1 is required for tooth germ development. , Bone, 38(6): 836-844, 2006, 2006.06.
23. Akhter M, Kobayashi I, Kiyoshima T, Matsuo K, Yamaza H, Wada H, Honda JY, Ming X, Sakai H., Possible functional involvement of thymosin beta 4 in developing tooth germ of mouse lower first molar., Histochem Cell Biol., 10.1007/s00418-005-0040-x, 124, 3-4, 207-213, 124(3-4): 207-213, 2005, 2005.09.
24. Wada H, Kobayashi I, Yamaza H, Matsuo K, Kiyoshima T, Akhtar M, Sakai T, Koyano K, Sakai H., In situ expression of heat shock proteins, Hsc73, Hsj2 and Hsp86 in the developing tooth germ of mouse lower first molar., Histochem J. , 10.1023/A:1020930228303, 34, 3-4, 105-109, 34(3-4): 105-109, 2002, 2002.03.
25. Yamaza H, Matsuo K, Kobayashi I, Wada H, Kiyoshima T, Akhtar M, Ishibashi Y, Sakai T, Akamine A, Sakai H., Expression of Set-alpha during morphogenesis of mouse lower first molar., Histochem J., 10.1023/A:1014491111628, 33, 8, 437-441, 33(8): 437-441, 2001, 2001.08.
26. Yamaza H, Matsuo K, Kiyoshima T, Shigemura N, Kobayasi I, Wada H, Akamine A, Sakai H., Detection of differentially expressed genes in the early developmental stage of the mouse mandible., Int J Dev Biol., 45, 4, 675-680, 45(4):675-678, 2001, 2001.06.
27. Shigemura N, Kiyoshima T, Sakai T, Matsuo K, Momoi T, Yamaza H, Kobayashi I, Wada H, Akamine A, Sakai H., Localization of activated caspase-3-positive and apoptotic cells in the developing tooth germ of the mouse lower first molar., Histochem J., 10.1023/A:1017900305661, 33, 5, 253-258, 33(5): 253-258, 2001, 2001.03.
Presentations
 Show All Presentations >>
1. Hiroko Wada, Shintaro Kawano, Seiji Nakamura and Tamotsu Kiyoshima, A case of extramammary Paget’s disease occurring in the hard palate of patient with oral squamous cell carcinoma, 第29回日本臨床口腔病理学会, 2018.08.
2. Misaki Abe, Hiroko Wada, Tamotsu Kiyoshima, Expression and function of Piezo1 and Piezo2 in tooth germ development, Kyudai Oral Bioscience 2018, 2018.02.
3. Hiroko Wada, Koki Nagano, Yurie Mikami, Misaki Abe, Tomohiro Yamada, Yoshihide Mori and Tamotsu Kiyoshima , A case of Plasmablastic lymphoma arising in oral cavity and extraoral site, 第28回日本臨床口腔病理学会, 2017.08.
4. 和田 裕子, 長谷川 佳那, Kengo Nagata, Naohisa Wada, 三上　友理恵, Hidetaka Sakai, 清島 保, The expression pattern of the FRG1 in the mouse developing tooth germ, IADR General Session & Exhibition, 2017.03.
5. 和田 裕子, 金城　亜紀, 三上　友理恵, 杉浦 剛, 清島 保, Mandibular tumor, 第27回日本臨床口腔病理学会, 2016.08.
6. Furusho K, Wada H, Mikami Y, Kiyoshima T, The expression of Netrin-1 and its receptor DCC in oral squamous cell carcinoma, Kyudai Oral Bioscience (KOB), 2015.02.
Membership in Academic Society
  • Japanese Association of Oral Biology
  • Japanese Society of Oral Pathology
Educational
Other Educational Activities
  • 2021.05.
  • 2020.05.
  • 2019.05.
  • 2018.05.
  • 2017.05.
  • 2015.05.
  • 2014.05.
  • 2013.07.
  • 2012.07.
  • 2011.07.
  • 2010.07.


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