Kyushu University Academic Staff Educational and Research Activities Database
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Tomotake Tokunou (Tokuno) Last modified date:2021.05.05

Lecturer / Internal Medicine
Kyushu University Hospital

 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Field of Specialization
Total Priod of education and research career in the foreign country
Research Interests
  • Treatment of heart failure and peripheral vascular disease by hyperthermia
    keyword : peripheral vascular disease, heart failure
  • Anti-inflammation by hypoxia signaling
    keyword : hypoxia, HIF
  • Hypoxic response with sleep apnea syndrome
    keyword : Sleep apnea syndrome, hypoxia
  • Regeneration and repair of cardiovascular tissue
    keyword : tissue repair, growth factors
Academic Activities
1. Tomotake Tokunou, Shin-ichi Ando, Recent advances in the management of secondary hypertension—obstructive sleep apnea, Hypertension Research, 10.1038/s41440-020-0494-1, 2020.06.
1. Sawatari H, Chishaki A, Nishizaka M, Miyazono M, Tokunou T, Magota C, Yamamoto U, Handa S, Ando SI., Accumulated nocturnal hypoxemia predict arterial endothelial function in patients with sleep-disordered breathing with or without chronic heart failure., Heart and Vessels., 10.1007/s00380-020-01557-5., 35, 6, 800-807, 2020.06.
2. Kojima H, Tokunou T, Takahara Y, Sunagawa K, Hirooka Y, Ichiki T, Tsutsui H., Hpoxia-inducible factor-1α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension., Physiological Reports, 10.14814/phy2.14025., 7, 7, e14025, 2019.04.
3. Higuchi Y, Niidome T, Miyamoto Y, Komohara Y, Tokunou T, Kubota T, Horiuchi T., Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α., Heart and Vessels, 34, 538-544, 2019.03.
4. Takahara Y, Tokunou T, Ichiki T, Suppression of Abdominal Aortic Aneurysm Formation in Mice by Teneligliptin, a Dipeptidyl Peptidase-4 Inhibitor., J Atheroscler Thromb., 10.5551/jat.42481., 2018.01.
5. Takahara Y, Tokunou T, Kojima H, Hirooka Y, Ichiki T., Deletion of Hypoxia-Inducible Factor-1α in Myeloid Lineage Exaggerates Angiotensin II-Induced Formation of Abdominal Aortic Aneurysm., Clin Sci (Lond)., 131, 7, 609-620, 2017.04.
1. Tomotake Tokunou, Toyoki Maeda, Takahiko Horiuchi, Naoki Makino, Telomere shortening is accelerated in a gender-differential manner in patients with insomnia receiving sleep medication., 5th Asean Sleep Federation Congress, 2019.11.