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Masaki Katsuhisa Last modified date：2024.01.13

Lecturer / Department of Neurology, Neurological Institute, Graduate School of Medical Sciences
Neurology
Kyushu University Hospital




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Homepage
https://kyushu-u.elsevierpure.com/en/persons/katsuhisa-masaki
　Reseacher Profiling Tool　Kyushu University Pure
Phone
092-642-5340
Fax
092-642-5352
Academic Degree
MD, PhD
Country of degree conferring institution (Overseas)
Yes
Field of Specialization
Neurology
Total Priod of education and research career in the foreign country
02years00months
Research
Research Interests
  • TDP-43 proteinopathy in TMEV infection
    keyword : TMEV, TDP-43, multiple sclerosis, demyelination, amyotrophic lateral sclerosis
    2016.12～2018.11.
  • A novel model for treatment of hypertrophic pachymeninigitis
    keyword : hypertrophic pachymeningitis, LATY136F mutant mice
    2017.06～2021.06.
  • Expression of mutant α-synucelin in oligodendrocytes induces remarkable glial inflammation and demyelination
    keyword : αsynuclein oligodendrocyte neurodegeneration microglia astrocyte
    2018.12～2021.06.
  • Glial assenbly and their early disruption in demyelinating disorders
    keyword : connexin, astrocyte, oligodendrocyte, multiple sclerosis, glia assenbly
    2015.06～2021.06.
  • Neuroimmunology and neuropathological study of human demyelinating disorders
    keyword : multiple sclerosis, neuromyelitis optica, Balo's disease
    2008.04～2021.03.
Academic Activities
Reports
 Show All Reports >>
1. Masaki K., Recent advances in understanding connexin gap junction pathology in demyelinating diseases, Clin Exp Neuroimmunol, 2020.03.
2. Hayashida S, Masaki K, Kira J, Extensive white matter pathology of longitudinally extensive myelitis in neuromyelitis optica, Clin Exp Neuroimmunol, 2017.02.
3. Hayashida S, Masaki K, Matsushita T, Watanabe M, Yamasaki R, Murai H, Kira J , Holocord involvement with sparing of the peripheral white matter rim in longitudinally extensive spinal cord lesions of neuromyelitis optica, Clinical and Experimental Neuroimmunology, 2015.12.
4. Masaki K., Early disruption of glial communication via connexin gap junction in multiple sclerosis, Baló's disease and neuromyelitis optica., Neuropathology, 2015.10.
5. Masaki K., Loss of connexins might cause extensive demyelination in Baló's disease, Clinical and Experimental Neuroimmunology, 2013.06.
Papers
 Show All Papers >>
1. Hayashida H, Masaki K, Ogata H, Yamaguchi T, Tanaka K, Arimura K, Maruoka Y, Kikuchi K, Togao O, Yamasaki R, Isobe N, Focal 18F-fluorodeoxyglucose uptake in spinal dural arteriovenous fistula: A report of two cases, Neurology and Clinical Neuroscience, 2024.01.
2. Nishimura Y, Masaki K, Matsuse D, Yamaguchi H, Tanaka T, Matsuo E, Hayashida S, Watanabe M, Matsushita T, Sadashima S, Sasagasako N, Yamasaki R, Isobe N, Iwaki T, Kira JI. , Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy. , Brain Pathol, 10.1111/bpa.13131. , 2022.11.
3. Takeuchi H, Masaki K, Ogata H, Nagata S, Shimogawa T, Yamasaki R, Isobe N., Reversible Parkinsonism Caused by Lumboperitoneal Shunt Overdrainage., Neurology, 2022.07.
4. Matsushita T, Masaki K, Isobe N, Sato S, Yamamoto K, Nakamura Y, Watanabe M, Suenaga T, Kira JI; Japan Multiple Sclerosis Genetic Consortium., Genetic factors for susceptibility to and manifestations of neuromyelitis optica, Ann Clin Transl Neurol, 2020.09.
5. Hayashida S, Masaki K, Suzuki SO, Yamasaki R, Watanabe M, Koyama S, Isobe N, Matsushita T, Takahashi K, Tabira T, Iwaki T, Kira JI. , Distinct microglial and macrophage distribution patterns in the concentric and lamellar lesions in Baló's disease and neuromyelitis optica spectrum disorders, Brain Pathol, 2020.09.
6. Richard C, Ruiz A, Cavagna S, Bigotte M, Vukusic S, Masaki K, Suenaga T, Kira JI, Giraudon P, Marignier R. , Connexins in neuromyelitis optica: a link between astrocytopathy and demyelination, Brain, 2020.09.
7. Masaki K, Sonobe Y, Ghadge G, Pytel P, Lépine P, Pernin F, Cui QL, Antel JP, Zandee S, Prat A, Roos RP., RNA-binding Protein Altered Expression and Mislocalization in MS, Neurol Neuroimmunol Neuroinflamm, 2020.03.
8. Zhao Y, Yamasaki R, Yamaguchi H, Nagata S, Une H, Cui Y, Masaki K, Nakamuta Y, Iinuma K, Watanabe M, Matsushita T, Isobe N, Kira JI., Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis., Proc Natl Acad Sci U S A, 2020.01.
9. Masaki K, Sonobe Y, Ghadge G, Pytel P, Roos RP., TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection., PLoS Pathogens, 2019.02.
10. Cui Y, Masaki K, Zhang X, Yamasaki R, Fujii T, Ogata H, Hayashida S, Yamaguchi H, Hyodo F, Eto H, Koyama S, Iinuma K, Yonekawa T, Matsushita T, Yoshida M, Yamada K, Kawano M, Malissen M, Malissen B, Kira J., A novel model for treatment of hypertrophic pachymeningitis., Ann Clin Transl Neurol, 2019.01.
11. Kobayakawa Y, Masaki K, Yamasaki R, Shiraishi W, Hayashida S, Hayashi S, Okamoto K, Matsushita T, Kira JI., Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis., Front Neurosci., 2018.11.
12. Sonobe Y, Ghadge G, Masaki K, Sendoel A, Fuchs E, Roos RP., Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress., Neurobiol Dis., 2018.08.
13. Hayashida S, Masaki K, Yonekawa T, Suzuki SO, Hiwatashi A, Matsushita T, Watanabe M, Yamasaki R, Suenaga T, Iwaki T, Murai H, Kira JI., Early and extensive spinal white matter involvement in neuromyelitis optica., Brain Pathol. , 2017.05.
14. Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, Suzumura A, Kira JI., Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation., Sci Rep. , 2016.12.
15. Yamasaki R, Fujii T, Wang B, Masaki K, Kido MA, Yoshida M, Matsushita T, Kira JI., Allergic Inflammation Leads to Neuropathic Pain via Glial Cell Activation., J Neurosci., 2016.11.
16. Cui Y, Masaki K, Yamasaki R, Imamura S, Suzuki SO, Hayashi S, Sato S, Nagara Y, Kawamura MF, Kira J., Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model., J Neuroinflammation, 10.1186/1742-2094-11-42., 6, 11, 42, 2014.03.
17. Masaki K, Suzuki SO, Matsushita T, Matsuoka T, Imamura S, Yamasaki R, Suzuki M, Suenaga T, Iwaki T, Kira J., Connexin 43 astrocytopathy linked to rapidly progressive multiple sclerosis and neuromyelitis optica., PLOS ONE, e72919, 2013.08.
18. Masaki K, Suzuki SO, Matsushita T, Yonekawa T, Matsuoka T, Isobe N, Motomura K, Wu XM, Tabira T, Iwaki T, Kira J., Extensive loss of connexins in Baló's disease: evidence for an auto-antibody-independent astrocytopathy via impaired astrocyte-oligodendrocyte/myelin interaction., Acta Neuropathologica, 123, 887-900, 2012.06.
Presentations
 Show All Presentations >>
1. Katsuhisa Masaki, Approach to tumefactive brain lesions, the Pan Asian Course for Training in MS And Neuroimmunology (PACTMAN), 2023.05.
2. Katsuhisa Masaki, Glial pathology of multiple sclerosis, neuromyelitis optica spectrum disorders; insight from human pathology and genetics, The 12th PACTRIMS, 2019.11.
3. Katsuhisa Masaki, Glial pathology of multiple sclerosis, neuromyelitis optica spectrum disorders and Baló’s disease
, 第60回日本神経学会学術大会, 2019.05.
4. Katsuhisa Masaki, Update and Review of Baló’s Concentric Sclerosis
, XXIII World Congress of Neurology, WCN2017, 2017.09.
5. Katsuhisa Masaki, Common and Distinct Features of Immunopathology Between MS and NMO, The 8th PACTRIMS, 2015.11.
6. Katsuhisa Masaki, Extensive Loss of Astrocytic Monocarboxylate Transporter 4 in Active Lesions of Multiple Sclerosis and Neuromyelitis Optica, The 31st ECTRIMS, 2015.10.
7. Katsuhisa Masaki, Connexin gap junction pathology in MS, Baló’s disease and NMO
, The 55th Annual Meeting of the Japanese Society of Neuropathology 日本神経病理学会, 2014.06.
8. Katsuhisa Masaki, Connexin gap junction pathology in active MS, Baló’s disease and NMO
, The 55th Annual Meeting of the Japanese Society of Neurology　日本神経学会学術大会, 2014.05.
9. Katsuhisa Masaki, Rapidly progressive multiple sclerosis and gliopathy, The 6th PACTRIMS, 2013.11.
10. Katsuhisa Masaki, Connexin gap junction pathology in active MS, Baló’s disease and NMO
, 第12回MSワークショップ, 2013.08.
11. Katsuhisa Masaki, Early disruption of astrocytic connexins in multiple sclerosis, Baló’s disease and neuromyelitis optica., The 28th ECTRIMS, 2012.10.
12. Masaki K and Kira J, Connexins in Demyelinating Disorders, The 35th Annual Meeting of the Japan Neuroscience Society, 2012.09.
13. Katsuhisa Masaki, Molecular pathology of astrocytopathy in Baló’s disease and tumefactive MS., The 5th PACTRIMS, 2012.09.
14. Katsuhisa Masaki, Anti-AQP4 antibody-independent astrocytopathy with extensive connexin loss in Balo’s concentric sclerosis and allied conditions, The 63rd American Academy of Neurology, 2011.04.
Educational
Other Educational Activities
  • 2020.02.
  • 2019.09.
  • 2018.12.


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