| 1. |
Fumi Irie, Ryu Matsuo, Kuniyuki Nakamura, Yoshinobu Wakisaka, Tetsuro Ago, Takanari Kitazono, Masahiro Kamouchi, Sex Differences in Long-Term Functional Decline after Ischemic Stroke: A Longitudinal Observational Study from the Fukuoka Stroke Registry, Cerebrovasc Dis, 52, 4, 409-416, 2023.06. |
| 2. |
Kayo Wakisaka, Ryu Matsuo, Koutarou Matsumoto, Yasunobu Nohara, Fumi Irie, Yoshinobu Wakisaka , Tetsuro Ago , Naoki Nakashima, Masahiro Kamouchi, Takanari Kitazono, Non-linear association between body weight and functional outcome after acute ischemic stroke, Sci Rep, 13, 1, 8697, 2023.05. |
| 3. |
Kuniyuki Nakamura, Kana Ueki, Ryu Matsuo, Takuya Kiyohara, Fumi Irie, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono, Association between decreases in serum uric acid levels and unfavorable outcomes after ischemic stroke: A multicenter hospital-based observational study, PLoS One, 18, 6, e0287721, 2023.06. |
| 4. |
Ueki K, Matsuo R, Kuwashiro T, Irie F, Wakisaka Y, Ago T, Kamouchi M, Kitazono T, Decreased estimated glomerular filtration rate and proteinuria and long-term outcomes after ischemic stroke: a longitudinal observational cohort study, Stroke, 2023.05. |
| 5. |
Shibahara T, Nakamura K, Wakisaka Y, Shijo M, Yamanaka K, Takashima M, Takaki H, Nakamura K, Hidaka M, Kitazono T, Ago T, PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectine and laminin for tissue repair and functional recovery, J Cereb Blood Flow Metab, 2023.04. |
| 6. |
Ohya Y, Matsuo R, Sato N, Irie F, Wakisaka Y, Ago T, Kamouchi M, Kitazono T, Modification of the effects of age on clinical outcomes through management of lifestyle-related factors in patients with acute ischemic stroke, J Neurol Sci , 2023.03. |
| 7. |
Takashima M, Nakamura K, Kiyohara T, Wakisaka Y, Hidaka M, Takaki H, Yamanaka K, Shibahara T, Wakisaka M, Ago T, Kitazono T, Low-dose sodium-glucose cotransporter 2 inhibitor ameliorates ischemic brain injury in mice through pericyte protection without glucose-lowering effects, Commun Biol, 2022.07. |
| 8. |
Yamanaka K, Nakamura K, Shibahara T, Takashima M, Takaki H, Hidaka M, Komori M, Yoshikawa Y, Wakisaka Y, Ago T, Kitazono T., Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice, Glia, 2022.11. |
| 9. |
Wakisaka Y., Processing Speed Domain of Cognitive Function for Screening Early Cognitive Impairment Among Individuals With Atrial Fibrillation, Circ J, 2022.08. |
| 10. |
Ohya Y, Matsuo R, Sato N, Irie F, Nakamura K, Wakisaka Y, Ago T, Kamouchi M, Kitazono T; Investigators for Fukuoka Stroke Registry., Causes of ischemic stroke in young adults versus non-young adults: A multicenter hospital-based observational study, PLoS One., 2022.07. |
| 11. |
Kiyohara T, Kumai Y, Yubi T, Ishikawa E, Wakisaka Y, Ago T, Kitazono T., Association between Early Cognitive Impairment and Short-Term Functional Outcome in Acute Ischemic Stroke, Cerebrovasc Dis., 2022.06. |
| 12. |
Shibahara T, Nakamura K, Abe D, Tagawa N, Wakisaka Y, Kitazono T, Ago T., Progressive Small-Vessel Strokes Following Antiretroviral Therapy in a Patient with Acquired Immunodeficiency Syndrome, J Stroke Cerebrovasc Dis, 2022.05. |
| 13. |
Nakanishi Y, Furuta Y, Hata J, Yubi T, Oishi E, Sakata S, Hirakawa Y, Wakisaka Y, Ago T, Kitazono T, Ninomiya T., Long-Term Trends in The 5-Year Risk of Recurrent Stroke over A Half Century in A Japanese Community: The Hisayama Study, J Atheroscler Thromb, 2022.02. |
| 14. |
Irie F, Matuso R, Nakamura K, Wakisaka Y, Ago T, Kamouchi M, Kitazono T
, Sex differences in the risk of 30-day death after acute ischemic stroke, Neurol Clin Pract , 11, e809-e816, 2021.12. |
| 15. |
Fukuda K, Matsuo R, Kamouchi M, Kiyuna F, Sato N, Nakamura K, Hata J, Wakisaka Y, Ago T, Imaizumi T, Kai H, Kitazono T, Day-by-Day Blood Pressure Variability in the Subacute Stage of Ischemic Stroke and Long-Term Recurrence., Stroke, 2021.09. |
| 16. |
Kiyohara T, Matsuo R, Hata J, Nakamura K, Wakisaka Y, Kamouchi M, Kitazono T, Ago T, β-Cell Function and Clinical Outcome in Nondiabetic Patients With Acute Ischemic Stroke., Stroke, 2021.08. |
| 17. |
Wakisaka Y, Matsuo R, Nakamura K, Ago T, Kamouchi M, Kitazono T, Pre-Stroke Cholinesterase Inhibitor Treatment Is Beneficially Associated with Functional Outcome in Patients with Acute Ischemic Stroke and Pre-Stroke Dementia: The Fukuoka Stroke Registry., Cerebrovasc Dis, 2021.04. |
| 18. |
Sato N, Matsuo R, Kiyuna F, Nakamura K, Hata J, Wakisaka Y, Ago T, Kamouchi M, Kitazono T, Anticoagulation and Risk of Stroke Recurrence in Patients with Embolic Stroke of Undetermined Source Having No Potential Source of Embolism.
, Cerebrovasc Dis, 2020.12. |
| 19. |
Momosaka D, Togao O, Kikuchi K, Kikuchi Y, Wakisaka Y, Hiwatashi A., Correlations of amide proton transfer-weighted MRI of cerebral infarction with clinico-radiological findings.
, PLoS One, 2020.08. |
| 20. |
Shibahara T, Ago T, Nakamura K, Tachibana M, Yoshikawa Y, Komori M, Yamanaka K, Wakisaka Y, Kitazono T., Pericyte-Mediated Tissue Repair through PDGFRβ Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke.
, eNeuro, 2020.03. |
| 21. |
Matsuo R, Ago T, Kiyuna F, Sato N, Nakamura K, Kuroda J, Wakisaka Y, Kitazono T, Smoking Status and Functional Outcomes After Acute Ischemic Stroke.
, Stroke, 2020.03. |
| 22. |
Wakisaka Y., Possible Biomarker for an Important Yet Neglected Symptom After Stroke - Metalloproteinase-9 and Post-Stroke Depression.
, Circ J, 2019.10. |
| 23. |
Miura S, Miyata R, Matsumoto S, Higashi T, Wakisaka Y, Ago T, Kitazono T, Iihara K, Shimodozono M., Quality Management Program of Stroke Rehabilitation Using Adherence to Guidelines: A Nationwide Initiative in Japan.
, J stroke Cerebrovasc Dis, 2019.09. |
| 24. |
Komori M, Ago T, Wakisaka Y, Nakamura K, Tachibana M, Yoshikawa Y, Shibahara T, Yamanaka K, Kuroda J, Kitazono T., Early initiation of a factor Xa inhibitor can attenuate tissue repair and neurorestoration after middle cerebral artery occlusion., Brain Res, 2019.09. |
| 25. |
Kuroda J, Matsuo R, Yamaguchi Y, Sato N, Kamouchi M, Hata J, Wakisaka Y, Ago T, Kitazono T, Poor glycemic control and posterior circulation ischemic stroke.
, Neurol Clin Pract, 2019.08. |
| 26. |
Shono Y, Sugimori H, Matsuo R, Fukushima Y, Wakisaka Y, Kuroda J, Ago T, Kamouchi M, Kitazono T., Safety of antithrombotic therapy for patients with acute ischemic stroke harboring unruptured intracranial aneurysm.
, Int J stroke, 2018.10. |
| 27. |
Kiyuna F, Sato N, Matsuo R, Kamouchi M, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke.
, JAMA Netw Open, 2018.09. |
| 28. |
Yoshikawa Y, Ago T, Kuroda J, Wakisaka Y, Tachibana M, Komori M, Shibahara T, Nakashima H, Nakashima K, Kitazono T., Nox4 Promotes Neural Stem/Precursor Cell Proliferation and Neurogenesis in the Hippocampus and Restores Memory Function Following Trimethyltin-Induced Injury.
, Neuroscience, 2018.04. |
| 29. |
Ago T, Matsuo R, Hata J, Wakisaka Y, Kuroda J, Kitazono T, Kamouchi M, Insulin resistance and clinical outcomes after acute ischemic stroke.
, Neurology, 2018.04. |
| 30. |
Matsuo R, Yamaguchi Y, Matsushita T, Hata J, Kiyuna F, Fukuda K, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Kamouchi M, Association Between Onset-to-Door Time and Clinical Outcomes After Ischemic Stroke.
, Stroke, 2017.11. |
| 31. |
Tachibana M, Ago T, Wakisaka Y, Kuroda J, Shijo M, Yoshikawa Y, Komori M, Nishimura A, Makihara N, Nakamura K, Kitazono T., Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons.
, Stroke, 2017.08. |
| 32. |
Wakisaka Y, Matsuo R, Hata J, Kuroda J, Kitazono T, Kamouchi M, Ago T, Adverse influence of pre-stroke dementia on shor-term functional outcomes in patients with acute ischemic stroke: the Fukuoka Stroke Registry., Cerebrovasc Dis, 43, 82-89, 2017.01. |
| 33. |
Ishikawa H, Wakisaka Y, Matsuo R, Makihara N, Hata J, Kuroda J, Ago T, Kitayama J, Nakane H, Kamouchi M, Kitazono T, Influence of Statin Pretreatment on Initial Neurological Severity and Short-Term Functional Outcome in Acute Ischemic Stroke Patients: The Fukuoka Stroke Registry., Cerebrovasc Dis, 42, 5-6, 395-401, 2016.12. |
| 34. |
Matsuo R, Ago T, Hata J, Wakisaka Y, Kuroda J, Kuwashiro T, Kitazono T, Kamouchi M, Plasma C-Reactive Protein and Clinical Outcomes after Acute Ischemic Stroke: A Prospective Observational Study.
, PLoS One, 2016.06. |
| 35. |
Nishimura A, Ago T, Kuroda J, Arimura K, Tachibana M, Nakamura K, Wakisaka Y, Sadoshima J, Iihara K, Kitazono T., Detrimental role of pericyte Nox4 in the acute phase of brain ischemia.
, J Cereb Blood Flow, 2016.06. |
| 36. |
Nakamura K, Arimura K, Nishimura A, Tachibana M, Yoshikawa Y, Makihara N, Wakisaka Y, Kuroda J, Kamouchi M, Ooboshi H, Kitazono T, Ago T., Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke.
, Brain Res, 2016.06. |
| 37. |
Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Nakane H, Imaizumi T, Kitazono T, Day-by-Day Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry.
, Stroke, 2015.07. |
| 38. |
Irie F, Kamouchi M, Hata J, Matsuo R, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Sex differences in short-term outcomes after acute ischemic stroke: the fukuoka stroke registry.
, Stroke, 2015.02. |
| 39. |
Makihara N, Arimura K, Ago T, Tachibana M, Nishimura A, Nakamura K, Matsuo R, Wakisaka Y, Kuroda J, Sugimori H, Kamouchi M, Kitazono T., Involvement of platelet-derived growth factor receptor β in fibrosis through extracellular matrix protein production after ischemic stroke.
, Exp Neurol, 2015.02. |
| 40. |
Matsuo R, Kamouchi M, Fukuda H, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T, Intravenous thrombolysis with recombinant tissue plasminogen activator for ischemic stroke patients over 80 years old: the Fukuoka Stroke Registry.
, PLoS One, 2014.10. |
| 41. |
Matsuo R, Kamouchi M, Ago T, Hata J, Shono Y, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T, Thrombolytic therapy with intravenous recombinant tissue plasminogen activator in Japanese older patients with acute ischemic stroke: Fukuoka Stroke Registry.
, Geriatr Gerontrol Int, 2014.10. |
| 42. |
Kuroda J, Ago T, Nishimura A, Nakamura K, Matsuo R, Wakisaka Y, Kamouchi M, Kitazono T., Nox4 is a major source of superoxide production in human brain pericytes.
, J Vasc Res, 2014.07. |
| 43. |
Matsuo R, Ago T, Hata J, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T, Kamouchi M, Impact of the 1425G/A polymorphism of PRKCH on the recurrence of ischemic stroke: Fukuoka Stroke Registry.
, J stroke Cerebrovasc Dis, 2014.07. |
| 44. |
Murao K, Leys D, Jacquin A, Kitazono T, Bordet R, Béjot Y, Kimura K, Godefroy O, Wakisaka Y, Moulin S, Ago T, Sibon I, Bombois S, Mas JL, Hénon H, Pasquier F, Giroud M, Cordonnier C, Okada Y, Thrombolytic therapy for stroke in patients with preexisting cognitive impairment.
, Neurology, 2014.06. |
| 45. |
Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Hata J, Gotoh S, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T, Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke., Journal of Neurological Science, 340, 75-79, 2014.05, Background: Ischemic stroke is accompanied by an inflammatory response, which exacerbates brain injury and deteriorates functional outcome. S100A12 is expressed abundantly in granulocytes, and has been implicated to play an important role on inflammatory reactions in various disease states. We aimed to determine the association between plasma S100A12 levels and a functional outcome in patients with acute ischemic stroke.
Methods: We prospectively included 171 patients with acute ischemic stroke within 24 hours after onset in this study. Plasma samples were collected for the measurement of S100A12 levels. Poor functional outcome was defined as a modified Rankin Scale of 2-6 at day 90 after stroke onset.
Results: Of 171 patients, 74 (43.3%) had a poor functional outcome at day 90 after stroke onset. Plasma S100A12 levels on admission were significantly higher in patients with a poor functional outcome (2.1 [1.2–5.1] ng/mL, median [interquartile]) than in those with a favorable outcome (1.1 [0.5–2.0] ng/mL; pConclusions: High plasma S100A12 levels on admission are associated with a poor functional outcome in patients with acute ischemic stroke.. |
| 46. |
Wakisaka Y, Chu Y, Miller JD, Rosenberg GA, Heistad DD., Critical role for CuZn-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice., Stroke, 41, 790-797, 2010.04. |
| 47. |
Wakisaka Y, Chu Y, Miller JD, Rosenberg GA, Heistad DD., Spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice., J Cereb Blood Flow Metab, 30, 56-69, 2010.01. |
| 48. |
Heistad DD, Wakisaka Y, Miller J, Chu Y, Pena-Silva R., Novel aspects of oxidative stress in cardiovascular diseases.
, Circ J, 2009.02. |
| 49. |
Fujimi K, Sasaki K, Noda K, Wakisaka Y, Tanizaki Y, Matsui Y, Sekita A, Iida M, Kiyohara Y, Kanba S, Iwaki T., Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: the Hisayama study.
, Brain Pathol, 2008.07. |
| 50. |
Wakisaka Y, Miller JD, Chu Y, Baumbach GL, Wilson S, Faraci FM, Sigmund CD, Heistad DD., Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage, J Cereb Blood Flow Metab, 28, 1175-1185, 2008.06. |
| 51. |
Fujimi K, Noda K, Sasaki K, Wakisaka Y, Tanizaki Y, Iida M, Kiyohara Y, Kanba S, Iwaki T., Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study.
, Dement Geriatr Cogn Disord, 2007.04. |
| 52. |
Noda K, Sasaki K, Fujimi K, Wakisaka Y, Tanizaki Y, Wakugawa Y, Kiyohara Y, Iida M, Aizawa H, Iwaki T., Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study.
, Neuropathology, 2006.12. |
| 53. |
Wakisaka Y, Santa N, Doh-ura K, Kitamoto T, Ibayashi S, Iida M, Iwaki T., Increased asymmetric pulvinar MRI signals in a case of Creutzfeldt–Jakob disease with florid plaques following a cadaveric dura mater graft, 2006.02. |
| 54. |
Wakisaka Y, Furuta A, Masuda K, Morikawa W, Kuwano M, Iwaki T., Cellular Distribution of NDRG1 Protein in the Rat Kidney and Brain During Normal Postnatal Development., 2003.11. |
| 55. |
Wakisaka Y, Furuta A, Tanizaki Y, Kiyohara Y, Iida M, Iwaki T., Age-associated prevalence and risk factors of Lewy body pathology in a general population: the Hisayama study., 2003.10. |
| 56. |
Sasaki K, Doh-ura K, Wakisaka Y, Iwaki T., Clusterin/apolipoprotein J is associated with cortical Lewy bodies: immunohistochemical study in cases with alpha-synucleinopathies.
, Acta Neuropathol, 2002.09. |
