| Naoya Shindo | Last modified date：2024.04.18 |
Lecturer /
創薬ケミカルバイオロジー分野
Department of Chemo-Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences
Department of Chemo-Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences
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Homepage
https://kyushu-u.elsevierpure.com/en/persons/naoya-shindo
Reseacher Profiling Tool Kyushu University Pure
Phone
092-642-6600
Academic Degree
Ph.D. in Pharmaceutical Sciences
Country of degree conferring institution (Overseas)
No
Field of Specialization
Medicinal chemistry, organic chemistry, chemical biology
ORCID(Open Researcher and Contributor ID)
0000-0002-2374-9896
Total Priod of education and research career in the foreign country
01years10months
Research
Research Interests
- Development of novel reactive warhead for highly target selective covalent inhibitors
keyword : covalent drug, medicinal chemistry, TCI
2013.06～2018.06.
Papers
| 1. | Daiki Yamane, Ryo Tetsukawa, Naoki Zenmyo, Kaori Tabata, Yuya Yoshida, Naoya Matsunaga, Naoya Shindo, Akio Ojida, Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines, Journal of Medicinal Chemistry, https://doi.org/10.1021/acs.jmedchem.3c00737, 66, 13, 9130-9146, 2023.07. |
| 2. | Daiki Yamane, Satsuki Onitsuka, Suyong Re, Hikaru Isogai, Rui Hamada, Tadanari Hiramoto, Eiji Kawanishi, Kenji Mizuguchi, Naoya Shindo*, Akio Ojida*, Selective covalent targeting of SARS-CoV-2 main protease by enantiopure chlorofluoroacetamide, Chemical Science, 10.1039/D1SC06596C, 13, 10, 3027-3034, 2022.02. |
| 3. | Keisuke Tokunaga, Mami Sato, Keiko Kuwata, Chizuru Miura, Hirokazu Fuchida, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Naoya Shindo*, Akio Ojida*, Bicyclobutane Carboxylic Amide as a Cysteine-Directed Strained Electrophile for Selective Targeting of Proteins, Journal of the American Chemical Society, 10.1021/jacs.0c07490, 142, 43, 18522-18531, 2020.10, [URL]. |
| 4. | Naoya Shindo, Hirokazu Fuchida, Mami Sato, Kosuke Watari, Tomohiro Shibata, Keiko Kuwata, Chizuru Miura, Kei Okamoto, Yuji Hatsuyama, Keisuke Tokunaga, Seiichi Sakamoto, Satoshi Morimoto, Yoshito Abe, Mitsunori Shiroishi, Jose M. M. Caaveiro, Tadashi Ueda, Tomonori Tamura, Naoya Matsunaga, Takaharu Nakao, Satoru Koyanagi, Shigehiro Ohdo, Yasuchika Yamaguchi, Itaru Hamachi, Mayumi Ono, Akio Ojida, Selective and reversible modification of kinase cysteines with chlorofluoroacetamides, Nature Chemical Biology, https://doi.org/10.1038/s41589-018-0204-3, 15, 3, 250-258, 2019.01. |
Presentations
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