Kyushu University [Naoya Shindo (Lecturer) Faculty of Pharmaceutical Sciences, Department of Chemo-Pharmaceutical Sciences]

Naoya Shindo

Last modified date：2023.11.28

Lecturer / 創薬育薬研究施設統括室 / Department of Chemo-Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences

Papers

1.	Daiki Yamane, Satsuki Onitsuka, Suyong Re, Hikaru Isogai, Rui Hamada, Tadanari Hiramoto, Eiji Kawanishi, Kenji Mizuguchi, Naoya Shindo, Akio Ojida, Selective covalent targeting of SARS-CoV-2 main protease by enantiopure chlorofluoroacetamide, Chemical Science, 10.1039/D1SC06596C, 13, 10, 3027-3034, 2022.02.
2.	Chizuru Miura, Naoya Shindo, Kei Okamoto, Keiko Kuwata, Akio Ojida, Fragment-Based Discovery of Irreversible Covalent Inhibitors of Cysteine Proteases Using Chlorofluoroacetamide Library, 10.1248/cpb.c20-00547, 68, 11, 1074-1081, 2020.11.
3.	Keisuke Tokunaga, Mami Sato, Keiko Kuwata, Chizuru Miura, Hirokazu Fuchida, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Naoya Shindo, Akio Ojida, Bicyclobutane Carboxylic Amide as a Cysteine-Directed Strained Electrophile for Selective Targeting of Proteins, Journal of the American Chemical Society, 10.1021/jacs.0c07490, 142, 43, 18522-18531, 2020.10, [URL].
4.	Mami Sato, Hirokazu Fuchida, Naoya Shindo, Keiko Kuwata, Keisuke Tokunaga, Guo Xiao-Lin, Ryo Inamori, Keitaro Hosokawa, Kosuke Watari, Tomohiro Shibata, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Mayumi Ono, Akio Ojida, Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines, ACS Medicinal Chemistry Letters, 10.1021/acsmedchemlett.9b00574, 11, 6, 1137-1144, 2020.04.
5.	Naoya Shindo, Hirokazu Fuchida, Mami Sato, Kosuke Watari, Tomohiro Shibata, Keiko Kuwata, Chizuru Miura, Kei Okamoto, Yuji Hatsuyama, Keisuke Tokunaga, Seiichi Sakamoto, Satoshi Morimoto, Yoshito Abe, Mitsunori Shiroishi, Jose M. M. Caaveiro, Tadashi Ueda, Tomonori Tamura, Naoya Matsunaga, Takaharu Nakao, Satoru Koyanagi, Shigehiro Ohdo, Yasuchika Yamaguchi, Itaru Hamachi, Mayumi Ono, Akio Ojida, Selective and reversible modification of kinase cysteines with chlorofluoroacetamides, Nature Chemical Biology, https://doi.org/10.1038/s41589-018-0204-3, 15, 3, 250-258, 2019.01.
6.	Akiyuki Nishimura, Tsukasa Shimauchi, Tomohiro Tanaka, Kakeru Shimoda, Takashi Toyama, Naoyuki Kitajima, Tatsuya Ishikawa, Naoya Shindo, Takuro Numaga-Tomita, Satoshi Yasuda, Yoji Sato, Koichiro Kuwahara, Yoshito Kumagai, Takaaki Akaike, Tomomi Ide, Akio Ojida, Yasuo Mori, Motohiro Nishida, Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardinal senescence, Science Signaling, 10.1126/scisignal.aat5185, 11, 556, eaat5185, 2018.11.
7.	Exploration of a Novel Warhead for Covalent Inhibitors with High Target Specificity: Development of Novel Irreversible Inhibitors.
8.	Naoya Matsunaga, Eriko Ikeda, Keisuke Kakimoto, Miyako Watanabe, Naoya Shindo, Akito Tsuruta, Hisako Ikeyama, Kengo Hamamura, Kazuhiro Higashi, Tomohiro Yamashita, Hideaki Kondo, Yuya Yoshida, Masaki Matsuda, Takashi Ogino, Kazutaka Tokushige, Kazufumi Itcho, Yoko Furuichi, Takaharu Nakao, Kaori Yasuda, Atsushi Doi, Toshiaki Amamoto, Hironori Aramaki, Makoto Tsuda, Kazuhide Inoue, Akio Ojida, Satoru Koyanagi, Shigehiro Ohdo, Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease, EBioMedicine, 10.1016/j.ebiom.2016.10.008, 13, 262-273, 2016, 13, 262, 2016.06.
9.	Hirokazu Fuchida, Shigekazu Tabata, Naoya Shindo, Ippei Takashima, Qiao Leng, Yuji Hatsuyama, Itaru Hamachi, Akio Ojida, Design of Coordination Interaction of Zn(II) Complex with Oligo-Aspartate Peptide to Afford a High-Affinity Tag-Probe Pair, Bulletin of the Chemical Society of Japan, 10.1246/bcsj.20150037, 88, 784-791, 2015.03.
10.	Ikuko Takahira, Hirakazu Fuchida, Shigekazu Tabata, Naoya Shindo, Shohei Uchinomiya, Itaru Hamachi, Akio Ojida, Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins, Bioorganic & Medicinal Chemistry Letters, 10.1016/j.bmcl.2014.04.096, 24, 2855-2858, 2014.03.
11.	Yuusuke Kuroda, Naoya Shindoh, Yoshiji Takemoto, Kiyosei Takasu, Selective Synthesis of Polysubstituted Dihydroquinolines and α,β-Unsaturated Amidines by a Catalytic Reaction of Ynamides with Ketimines, Synthesis, 10.1055/s-0033-1339191, 45, 2328-2336, 2013.05.

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