Kyushu University Academic Staff Educational and Research Activities Database
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Jun-ichiro Koga Last modified date:2020.09.17

Research Assistant Professor / Angiocardiology
Kyushu University Hospital

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Academic Degree
Country of degree conferring institution (Overseas)
Field of Specialization
Cardiovascular Medicine
Total Priod of education and research career in the foreign country
Research Interests
  • Development of macrophage-targeting novel therapeutics for treatments of atherosclerotic vascular diseases
    keyword : atherosclerosis, monocytes/macrophages, restenosis
Academic Activities
1. Koga J, Matoba T, Egashira K., Anti-inflammatory Nanoparticle for Prevention of Atherosclerotic Vascular Diseases., J Atheroscler Thromb., 2016.07.
2. Nakano T, Fukuda D, Koga J, Aikawa M., Delta-Like Ligand 4-Notch Signaling in Macrophage Activation., Arterioscler Thromb Vasc Biol., 2019.02.
1. Honda K, Matoba T, Antoku Y, Koga J, Ichi I, Nakano K, Tsutsui H, Egashira K., Lipid-Lowering Therapy With Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion: A Role of Serum Oxysterols., Arterioscler Thromb Vasc Biol., 38, 4, 757-771, 2018.04.
2. Mao Y, Koga J, Tokutome M, Matoba T, Ikeda G, Nakano K, Egashira K., Nanoparticle-mediated delivery of pitavastatin to monocytes/macrophages inhibits left ventricular remodeling after acute myocardial infarction by inhibiting monocyte-mediated inflammation., Int Heart J., 58, 4, 615-623, 2017.07.
3. Koga J, Nakano T, Dahlman JE, Figueiredo JL, Zhang H, Decano J, Khan OF, Niida T, Iwata H, Aster JC, Yagita H, Anderson DG, Ozaki CK, Aikawa M, Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure, Arterioscler Thromb Vasc Biol, 35, 11, 2343-2353, 2015.11.
4. Koga J, Matoba T, Egashira K, Kubo M, Miyagawa M, Iwata E, Sueishi K, Shibuya M, Sunagawa K, Soluble Flt-1 gene transfer ameliorates neointima formation after wire injury in flt-1 tyrosine kinase-deficient mice., Arterioscler Thromb Vasc Biol, 29, 4, 458-464, 2009.04.
5. Koga J, Egashira K, Matoba T, Kubo M, Ihara Y, Iwai M, Horiuchi M, Sunagawa K, Essential role of angiotensin II type 1a receptors in the host vascular wall, but not the bone marrow, in the pathogenesis of angiotensin II-induced atherosclerosis., Hypertens Res, 31, 9, 1791-1800, 2008.09.
1. Koga J, Fukuda D, Nakano T, Aikawa M, Macrophage Notch1 accelerates lesion formation in mechanically-injured mouse femoral arteries., ISA2015, 2015.05.
Membership in Academic Society
  • The Japanese Society of Internal Medicine
  • The Japanese Circulation Society
  • American Heart Association
  • The Japanese Vascular Biology and Medicine Organization.
  • Japan Atherosclerosis Society
  • The Japan Society for Drug Delivery System