| 1. |
Tokui H, Yahata H, Okabe Y, Magarifuchi N, Maenohara S, Hachisuga K, Tomonobe H, Kodama K, Yagi H, Yasunaga M, Onoyama I, Asanoma K, Oda Y, Nakamura M, Kato K, Complete reduction surgery of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy, International Cancer Conference Journal, 2024.01. |
| 2. |
Asanoma K, Yagi H, Onoyama I, Cui L, Hori E, Kawakami M, Maenohara S, Hachisuga K, Tomonobe H, Kodama K, Yasunaga M, Ohgami T, Okugawa K, Yahata H, Kitao H, Kato K, The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer, JBC, 2024.01. |
| 3. |
Hachisuga K, Kawakami M, Tomonobe H, Maenohara S, Kodama K, Yagi H, Yasunaga M, Onoyama I, Asanoma K, Yahata H, Kato K, Clinical Significance of Tumor Immune Microenvironment in Endometrial Endometrioid Carcinoma, Grade 1 With DNA Mismatch Repair Protein Loss, Int J Gynecol Pathol , 2024.01. |
| 4. |
Kodama K, Tateishi C, Oda T, Cui L, Kuramoto K, Yahata H, Okugaa K, Maenohara S, Yagi
H, Yasunaga M, Onoyama I, Asanoma K, Mori T, Katayama Y, Kato K
, Development of novel tracers for sentinel node identification in cervical cancer, Cancer Science, 2023.11. |
| 5. |
Masafumi Yasunaga, Hideaki Yahata, Kaoru Okugawa, Emiko Hori, Kazuhisa Hachisuga, Shoji Maenohara, Keisuke Kodama, Hiroshi Yagi, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, and Kiyoko Kato, Decision-making for Subsequent Therapy for Patients With Recurrent or Advanced Endometrial Cancer Based on the Platinum-free Interval, American Journal of Clinical Oncology, 10.1097/COC.0000000000001021, 2023.05. |
| 6. |
Kaoru Okugawa, Hideaki Yahata, Tatsuhiro Ohgami, Masafumi Yasunaga, Kazuo Asanoma, Hiroaki Kobayashi, Kiyoko Kato , An update of oncologic and obstetric outcomes after abdominal trachelectomy using the FIGO 2018 staging system for cervical cancer: a single-institution retrospective
analysis, J Gynecol Oncol, 2023.05. |
| 7. |
Ichiro Onoyama, Minoru Kawakami, Kazuhisa Hachisuga, Shoji Maenohara, Keisuke Kodama Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Kazuo Asanoma, Hideaki Yahata, Yuya Kitamura, Ryuichi Sakamoto, Daisuke Kiyozawa, Kiyoko Kato , Secondary Adrenal Insufficiency Due to Isolated ACTH Deficiency Induced by Pembrolizumab: A Report of Two Cases of Uterine Endometrial Cancer
, Reports, 2023.04. |
| 8. |
Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Minoru Kawakami, Shoji Maenohara, Keisuke Kodama, Yumiko Matsumura, Norio Hamada , Emiko Hori, Kazuhisa Hachisuga, Masafumi Yasunaga, Tatsuhiro Ohgami, Kaoru Okugawa, Hideaki Yahata and Kiyoko Kato
, Tumor-derived ARHGAP35 mutations enhance the Gα13-Rho signaling axis in human endometrial cancer, Cancer Gene Therapy, 2022.11. |
| 9. |
Kazuo Asanoma, Hideaki Yahata, Kaoru Okugawa, Tatsuhiro Ohgami, Masafumi Yasunaga, Keisuke Kodama, Ichiro Onoyama, Hironori Kenjo, Mototsugu Shimokawa and Kiyoko Kato, Impact of obesity on robotic-assisted surgery in patients with stage IA endometrial cancer and a low risk of recurrence: An institutional study, The journal of Obstetrics and Gynaecology Research, 2022.10. |
| 10. |
Masafumi Yasunaga, Hideaki Yahata, Kaoru Okugawa, Mototsugu Shimokawa,Yumiko Maeda, Emiko Hori, Keisuke Kodama, Hiroshi Yagi, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato, Prognostic impact of adding bevacizumab to carboplatin and paclitaxel for recurrent, persistent, or metastatic cervical cancer, Taiwanese Journal of Obstetrics & Gynecology, 61巻 818 - 822, 2022.09. |
| 11. |
Hideaki Yahata, Keisuke Kodama, Kaoru Okugawa, Kazuhisa Hachisuga, Nobuko Yasutake, Shoji Maenohara, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Hiroaki Kobayashi, Kenzo Sonoda, Shingo Baba, Kousei Ishigami, Yoshihiro Ohishi, Yoshinao Oda, Kiyoko Kato , Long-term follow up after sentinel node biopsy alone for early-stage cervical cancer, Gynecol Oncol, 2022.02. |
| 12. |
Yukiko Tada, MD, Masafumi Yasunaga, MD, PhD, Hiroshi Tomonobe, MD, Yuichi Yamada, MD, PhD, Emiko Hori, Kaoru Okugawa, MD, PhD, Hideaki Yahata, MD, Ph,
Yoshinao Oda, MD, PhD, and Kiyoko Kato, MD, PhD1, A Case of Malignant Phyllodes Tumor of the Breast Metastasizing to the Ovary, International Journal of Surgical Pathology, 10.1177/10668969211056912, 2021.12. |
| 13. |
Kaoru Okugawa, Hideaki Yahata, Kazuhisa Hachisuga, Hiroshi Tomonobe, Nobuko Yasutake. Keisuke Kodama, Hironori Kenjo, Hiroshi Yagi, Tatsuhiro Ohgami, Masafumi Yasunaga, Ichiro Onoyama, Kazuo Asanoma, Emiko Hori, Yoshihiro Ohishi, Yoshinao Oda, Kiyoko Kato, Evaluation of Clinical Significance of Lymphovascular Space Invasion in Stage IA Endometrial Cancer, Oncology, 10.1159/000521382, 2021.10. |
| 14. |
Masafumi Yasunaga, Hideaki Yahata, Kaoru Okugawa, Emiko Hori, Keisuke Kodama, Hiroshi Yagi, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato, Prognostic impact of the subclassification of Müllerian cancer stage IV in the FIGO 2014 staging system with a focus of extra-abdominal lymph node metastases, Int J Clin Oncol, 2021.03. |
| 15. |
Keisuke Kodama, Hideaki Yahata, Kaoru Okugawa, Hiroshi Tomonobe, Nobuko Yasutake, Sachiko Yoshida, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Emiko Hori, Mototsugu Shimokawa, Kiyoko Kato, Prognostic outcome and risk factors for recurrence after laser vaporization for cervical intraepithelial neoplasia: a single-center retrospective study, Int J Clin Oncol, 2021.01. |
| 16. |
Shinichiro Yamaguci, Hideaki Yahata, Kaoru Okugawa, Keisuke Kodama, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato, Hypersensitivity reaction to pegylated liposomal doxorubicin administration for Mullerian carcinoma in Japanese women, Journal of Obstetrics and Gynaecology Research, 2021.01. |
| 17. |
Teruhiko Kawamura, Hiroyuki Tomari, Ichiro Onoyama, Hiromitsu Araki, Masafumi Yasunaga, Cui Lin, Keiko Kawamura, Natsuko Yokota, Sachiko Yoshida, Hiroshi Yagi, Kazuo Asanoma, Kenzo Sonoda, Katsuko Egashira, Takashi Ito, Kiyoko Kato, Identification of genes associated with endometrial cell aging, Molecular Human Reproduction, 2020.12. |
| 18. |
Kaoru Okugawa, Hideaki Yahata, Kenzo Sonoda, Hiroshi Yagi, Tatsuhiro Ohgami, Masafumi Yasunaga, Ichiro Onoyama, Eisuke Kaneki, Kazuo Asanoma, Hiroaki Kobayashi, Kiyoko Kato, Evaluation of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer: a single-institution experience, Int J Clin Oncol, 2020.07. |
| 19. |
Hideaki Yahata, Kenzo Sonoda, Shusaku Inoue, Nobuko Yasutake, Keisuke Kodama, Hiroshi Yagi, Masafumi Yasunaga, Tatsuhiro Ohgami, Ichiro Onoyama, Eisuke Kaneki, Kaoru Okugawa, Kazuo Asanoma, Kiyoko Kato, Is Adjuvant Therapy Necessary for Patients with Intermediate-Risk Cervical Cancer after Open Radical Hysterectomy?, Oncology, 2020.07. |
| 20. |
Kaoru Okugawa, Hideaki Yahata, Kenzo Sonoda, Tatsuhiro Ohgami, Masafumi Yasunaga, Eisuke Kaneki, Kiyoko Kato, Safety evaluation of abdominal trachelectomy in patients with cervical tumors ≥2 cm: a single-institution, retrospective analysis, J Gynecol Oncol, 2020.03. |
| 21. |
Yahata H, Sonoda K, Okugawa K, Yagi H, Ohgami T, Yasunaga M, Onoyama I, Kaneki E, Asanoma K, Kato K, Survey of the desire to have children and engage in sexual activity after trachelectomy among young Japanese women with early-stage cervical cancer, J Obstet Gynaecol Res, 2019.11. |
| 22. |
Kodama K, Sonoda K, Kijima M, Yamaguchi S, Yagi H , Yasunaga M, Ohgami T, Onoyama I, Kaneki E, Okugawa K, Yahata H, Ohishi Y , Oda Y, Kato K, Retrospective Analysis of Treatment and Prognosis for Uterine Leiomyosarcoma: 10-year Experience of a Single Institute, Asia Pac J Clin Oncol, 2019.11. |
| 23. |
Yagi H, Onoyama I, Asanoma K, Hori E, Yasunaga M, Kodama K, Kijima M, Ohgami T, Kaneki E, Okugawa K, Yahata H, Kato K , Gα13-mediated LATS1 down-regulation contributes to epithelial-mesenchymal transition in ovarian cancer, FASEB J, 2019.09. |
| 24. |
Asanoma K, Hori E, Yoshida S, Yagi H, Onoyama I, Kodama K, Yasunaga M, Ohgami T, Kaneki E, Okugawa K, Yahata H, Kato K, Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells , Oncotarget, 2019.07. |
| 25. |
Okugawa K, Sonoda K, Ohgami T, Yasunaga M, Kaneki E, Yahata H, Kato K, Pelvic abscess: A late complication of abdominal trachelectomy for cervical cancer, J Obstet Gynaecol Res, 2019.02. |
| 26. |
Yahata H, Kobayashi H, Sonoda K, Kodama K, Yagi H, Yasunaga M, Ohgami T, Onoyama I, Kaneki E, Okugawa K, Baba S, Isoda T, Ohishi Y, Oda Y, Kato K., Prognostic outcome and complications of sentinel lymph node navigation surgery for early-stage cervical cancer , Int J Clin Oncol, 2018.12. |
| 27. |
Sonoda K, Yahata H, Okugawa K, Kaneki E, Ohgami T, Yasunaga M, Baba S, Oda Y, Honda H, Kato K., Value of Intraoperative Cytological and Pathological Sentinel Lymph Node Diagnosis in Fertility-Sparing Trachelectomy for Early-Stage Cervical Cancer.
, Oncology, 2018.10. |
| 28. |
Yoshida Y, Kaneki E, Kijima M, Kodama K, Yamaguchi S, Yagi H, Yasunaga M, Ohgami T, Onoyama I, Okugawa K, Yahata H, Sonoda K, Kato K., Two types of small cell carcinoma of the ovary: Two typical case reports.
, Gynecol Oncol Rep, 2018.07. |
| 29. |
Yahata H, Sonoda K, Yasunaga M, Ohgami T, Kawano Y, Kaneki E, Okugawa K, Kaku T, Kato K., Surgical treatment and outcome of early invasive adenocarcinoma of the uterine cervix (FIGO stage IA1).
, Asia Pac J Clin Oncol, 2018.04. |
| 30. |
Nari Yamamoto • Reiko Takeuchi • Daisuke Izuchi • Norihito Yuge • Masahide Miyazaki • Masafumi Yasunaga • Katsuko Egashira • Yousuke Ueoka • Yoshihito Inoue, Hysteroscopic adhesiolysis for patients with Asherman’s syndrome: menstrual and fertility outcomes, Reproductive Medicine and Biology , 12, 159-166, 2013.05. |
| 31. |
Masafumi Yasunaga, MD, PhD, Toshiaki Saito, MD, PhD, Takako Eto, MD, Masao Okadome, MD, PhD, Kazuya Ariyoshi, MD, PhD, Ken-ichi Nishiyama, MD, PhD, Yoshinao Oda, MD, PhD
, Dedifferentiated chondrosarcoma arising in a mature cystic teratoma of the ovary: a case report and review of the literature, International Journal of Gynecolgic Pathology, 2011.07. |
| 32. |
Nishimura I, Ohishi Y, Oda Y, Kishimoto J, Yasunaga M, Okuma E, Kobayashi H, Wake N, Tsuneyoshi M, Expression and localization of E-cadherin and β-catenin in uterine carcinosarcoma.
, Virchows Arch, 2011.01. |
| 33. |
Okuma E, Ohishi Y, Oda Y, Aishima S, Kurihara S, Nishimura I, Yasunaga M, Kobayashi H, Wake N, Tsuneyoshi M., Cytoplasmic and stromal expression of laminin γ 2 chain correlates with infiltrative invasion in ovarian mucinous neoplasms of gastro-intestinal type.
, Oncol Rep, 2010.12. |
| 34. |
Ohishi Y, Oda Y, Kurihara S, Kaku T, Yasunaga M, Nishimura I, Okuma E, Kobayashi H, Wake N, Tsuneyoshi M., Hobnail-like cells in serous borderline tumor do not represent concomitant incipient clear cell neoplasms.
, Hum Pathol, 2009.08. |
| 35. |
Masafumi Yasunaga1, MD, Yoshihiro Ohishi1, MD, PhD, Yoshinao Oda1, MD, PhD, Munechika Misumi3, MD, PhD, Atsuko Iwasa1, MD, PhD, Shuichi Kurihara1, MD, Izumi Nishimura1, MD, Emi Ohkuma1, MD, Hiroaki Kobayashi2, MD, PhD, Norio Wake2, MD, PhD and Masazumi Tsuneyoshi1, MD, PhD, Immunohistochemical characterization of mullerian mucinous borderline tumor (MMBT): Possible histogenetic link with serous borderline tumor (SBT) and low-grade endometrioid tumor (LG-ET)., Human Pathology, 2009.07, Mullerian mucinous borderline tumor (MMBT) and gastrointestinal mucinous borderline tumor (IMBT) are considered mucinous tumor subtypes. However, it has been reported that MMBT shares many clinicopathologic features with serous borderline tumor (SBT). Furthermore, some investigators have explained the histogenesis of MMBT by metaplastic and hyperplastic transformation of endometriosis [1].
The purpose of this study is to substantiate the concept that MMBT is histogenetically closer to SBT or low-grade endometrioid tumors than to IMBT by directly comparing their immunophenotype.
A total of 80 cases of low-grade ovarian tumors composed of 20 MMBTs, 20 IMBTs, 20 SBTs, and 20 low-grade endometrioid tumors (LG-ETs), were immunohistochemically evaluated for the expression of estrogen receptor (ER), progesterone receptor (PgR), vimentin, WT-1, beta-catenin and PTEN.
Almost all cases of MMBT, SBT, and LG-ET showed diffuse and strong nuclear expression of ER and PgR. In addition, about half of the MMBT, SBT, and LG-ET cases showed focal but strong vimentin cytoplasmic expression. In contrast, IMBT showed no expression of ER, PgR, or vimentin, except for one case in which ER expression was very focally and weakly observed. Beta-catenin nuclear expression was significantly more frequent in LG-ET than in MMBT, IMBT, or SBT. PTEN expression was significantly lower in LG-ET than in MMBT, IMBT and SBT. Multiple comparisons of quantitative immunoreactivities of ER, PgR, and vimentin revealed that the IMBT expression profiles were significantly different from those of MMBTs, SBTs, and LG-ETs.
The immunohistochemical expression profiles of ER, PgR, and vimentin substantiate the concept that the histogenesis of MMBT is closer to those of SBT and LG-ET than to that of IMBT. However, aberrant expression of bata-catenin and PTEN gene, both of which are known to contribute the tumorigenesis of LG-ET, appeared to be less important for the tumorigenesis of MMBT.
. |
| 36. |
Iwasa A, Oda Y, Kurihara S, Ohishi Y, Yasunaga M, Nishimura I, Takagi E, Kobayashi H, Wake N, Tsuneyoshi M., Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53- and p16/Rb-dependent cell cycle regulator proteins.
, Pathol Int., 2008.12. |
| 37. |
安永 昌史, 大石 善丈, 西村 和泉, 田宮 貞史, 岩佐 厚子, 高木 恵美, 井上 貴史, 矢幡 秀昭, 小林 裕明, 和氣 徳夫, 恒吉 正澄, Ovarian undifferentiated carcinoma resembling giant cell carcinoma of the lung, Pathology International, 58, 244-248, 2008.04. |
