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Daigaku Hasegawa Last modified date：2023.11.22

Lecturer / Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University
Oral Rehabilitation
Kyushu University Hospital




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Homepage
https://kyushu-u.elsevierpure.com/en/persons/daigaku-hasegawa
　Reseacher Profiling Tool　Kyushu University Pure
Phone
092-642-6432
Fax
092-642-6366
Academic Degree
doctor of dental science
Country of degree conferring institution (Overseas)
No
Field of Specialization
endodontology
Total Priod of education and research career in the foreign country
00years00months
Research
Research Interests
  • Creation of a novel periodontal tissue regeneration method based on stem cell conversion of periodontal ligament cells.
    keyword : periodontal stem cell, stem cell conversion, MEST
    2018.04.
  • Understanding Fate Determination of Craniofacial Skeletal Stem Cells
    keyword : Skeletal stem cells, β-catenin, GATA3
    2020.10～2022.03.
  • The effect of Wnt5a on human periodontal ligament cells
    keyword : periodontal ligament, Wnt signal pathway
    2011.04.
  • Development of the periodontal tissue regenerating method utilized a novel marker of periodontal ligament stem cells
    keyword : periodontal ligament, stem cell, regeneration
    2011.04～2020.09.
  • The role of Tenomodulin on the periodontal ligament tissue
    keyword : Periodontal ligament, Tenomodulin
    2016.04.
Academic Activities
Reports
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1. Hamano S, Sugiura R, Yamashita D, Tomokiyo A, Hasegawa D, Maeda H, Current Application of iPS Cells in the Dental Tissue Regeneration, Biomedicines, 10.3390/biomedicines10123269, 2022.12.
2. Yoshida S, Tomokiyo A, Hasegawa D, Hamano S, Sugii H, Maeda H, Insight into the Role of Dental Pulp Stem Cells in Regenerative Therapy, Biology (Basel), 2020.07.
3. Tomokiyo, A., Yoshida, S., Hamano, S., Hasegawa, D., Sugii, H. & Maeda, H., Detection, characterization, and clinical application of mesenchymal stem cells in periodontal ligament tissue, Stem Cells International., 2018.08.
Papers
 Show All Papers >>
1. Maruyama T (Co-First), Hasegawa D (Co-First), Valenta T, Haigh J, Bouchard M, Basler K, Hsu W, GATA3 mediates nonclassical β-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis, Science Advances, 2022.12.
2. Kaneko H, Hasegawa D, Itoyama T, Yoshida S, Tomokiyo A, Hamano S, Sugii H, Maeda H, Inhibition of c-Jun N-terminal kinase signaling promotes osteoblastic differentiation of periodontal ligament stem cells and induces regeneration of periodontal tissues, Archives of oral biology, 2022.02.
3. Tomokiyo A, Hasegawa D, Ono T, Nagano R, Ipposhi K, Yamashita K, Alhasan MA, Maeda H, Characterization of a clonal human periodontal ligament stem cell line exposed to methacrylate resin-, bioactive glass-, or silicon-based root canal sealers, Odontology, 2022.01.
4. Daigaku Hasegawa, Kana Hasegawa, Hiroshi Kaneko, Shinichiro Yoshida, Hiromi Mitarai, Mai Arima, Atsushi Tomokiyo, Sayuri Hamano, Hideki Sugii, Naohisa Wada, Tamotsu Kiyoshima, Hidefumi Maeda, MEST Regulates the Stemness of Human Periodontal Ligament Stem Cells, Stem Cells International, 10.1155/2020/9672673, 2020.07.
5. Mai Arima, Daigaku Hasegawa, Shinichiro Yoshida, Hiromi Mitarai, Atsushi Tomokiyo, Sayuri Hamano, Hideki Sugii, Naohisa Wada, Hidefumi Maeda , R-spondin 2 promotes osteoblastic differentiation of immature human periodontal ligament cells through the Wnt/β-catenin signaling pathway
, Journal of Periodontal Research, 2019.04.
6. Daigaku Hasegawa, Naohisa Wada, Hidefumi Maeda, Shinichiro Yoshida, Hiromi Mitarai, Atsushi Tomokiyo, Satoshi Monnouchi, Sayuri Hamano, Asuka Yuda, Akifumi Akamine, Wnt5a Induces Collagen Production by Human Periodontal Ligament Cells through TGFβ1-mediated Upregulation of Periostin Expression, Journal of Cellular Physiology, 10.1002/jcp.24950, 2015.02.
Presentations
 Show All Presentations >>
1. Kaneko H, Hasegawa D, Itoyama T, Yoshida S, Tomokiyo A, Hamano S, Sugii H, Maeda H, Inhibition of c-Jun N-terminal kinase affects regeneration of periodontal tissues, KOB & OBT 5th Joint International Symposium, 2021.11.
2. Hasegawa D, Wada N, Hamano S, Tomokiyo A, Yoshida S, Mitarai H, Sonoda M, Sugii H, Maeda H, Identification of a novel periodontal ligament stem cell marker, 94th General Session & Exhibition of the IADR, 2016.06.
3. Daigaku Hasegawa, Naohisa Wada, Hidefumi Maeda, Shinichiro Yoshida, Hiromi Mitarai, Atsushi Tomokiyo, Satoshi　Monnouchi, Sayuri Hamano, Asuka Yuda, Akifumi Akamine, The effects of Wnt5a on Human Periodontal Ligament Cells, 93rd General Session & Exhibition of the IADR, 2015.03.
4. Daigaku Hasegawa, Naohisa Wada, Hidefumi Maeda, Shinichiro Yoshida, Satoshi　Monnouchi, Katsuaki Koori, Sayuri Hamano, Hiromi Mitarai, Akifumi Akamine, The Efects of Wnt5a on Human Periodontal Ligament Cells, Kyudai Oral Bioscience 2014 -8th International Symposium, 2014.02.


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