Kyushu University Academic Staff Educational and Research Activities Database
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Takao Shimayoshi Last modified date:2021.08.04

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 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Ph.D. (Informatics)
Field of Specialization
Software Engineering, Computational Physiology, Computer Security
Research Interests
  • Practical information system
    keyword : Computer network, system architecture, information security
  • Methods for mathematical analysis of cell-physiology models
    keyword : Computational Physiology, Physiome
  • Multi-scale Simulation of Cardiovascular System
    keyword : Heart, Ventricle, Vascular system, Cell physiology, Electrophysiology, Structural mechanics
  • Formal method for numerical algorithms
    keyword : Software engineering, description language, numerical computation
Academic Activities
1. A Study on Confidential Information Protection in Kyushu University.
1. Takao Shimayoshi, Yuta Yamamoto, Tetsuya Matsuda, A Preliminary Computational Model for Hypoxic Acidosis in Cardiac Myocytes, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018, 2018.07, Intracellular acidosis induced by hypoxia resulted from myocardial ischemia damages myocardium. However, the detailed mechanisms of hypoxic acidosis are not quantitatively explained. The purpose of this study is to create a novel computational model which can reproduce intracellular acidosis caused by myocardial ischemia. We constructed a computational model of myocardium, by using a mathematical ventricular cell model which includes pH regulation and a computational model of myocardial microcirculation for calculating extracellular conditions. The present model reproduced cellular hypoxia in an ischemic condition simulated by a reduced blood flow, and intracellular pH reduction in response to the hypoxia..
Membership in Academic Society
  • Institute of Electrical and Electronics Engineers
  • Association for Computing Machinery
  • Information Processing Society of Japan
  • Institute of Electronics, Information and Communication Engineers
  • Japanese Society for Medical and Biological Engineering