Kyushu University Academic Staff Educational and Research Activities Database
Researcher information (To researchers) Need Help? How to update
Keisuke Tomohara Last modified date:2020.11.30

E-Mail *Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari.
 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Ph.D. (Kyoto University)
Field of Specialization
Medicinal chemistry
ORCID(Open Researcher and Contributor ID)
Research Interests
  • Mechanistic characterization of enzyme inhibitors by solvent-perturbation assay
    keyword : Perturbation
  • Chemical engineering of natural product extracts
    keyword : Natural product extract, Unnatural natural product
Academic Activities
1. 友原 啓介, ヨウ化アリールの連続的オルトアミノ化—イプソホウ素化反応, ファルマシア, 2015.11.
2. Keisuke Tomohara, Another aspect in use of DMSO in medicinal chemistry, Atlas of Science, 2016.10.
1. Keisuke Tomohara*, Nao Ohashi, Takeru Nose*, Mechanistic Insights into a DMSO-Perturbing Inhibitory Assay of Hyaluronidase, Biochemistry, ASAP, 2020.09.
2. Keisuke Tomohara*, Naoto Hasegawa, Isao Adachi, Yoshikazu Horino, Takeru Nose*., Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay., Bioorg. Med. Chem. Lett., 30, 126815, 2020.01.
3. Keisuke Tomohara*, Isao Adachi, Yoshikazu Horino, Hitoshi Kesamaru, Hitoshi Abe, Keitaro Suyama, Takeru Nose*., DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors., ACS Med. Chem. Lett., 10, 923-928, 2019.05.
1. Keisuke Tomohara, Isao Adachi, Hitoshi Kesamaru, Takeru Nose, Mechanistic Characterization of alpha-Chymotrypsin Inhibitors by DMSO-Perturbing Assay, 10th International Peptide Symposium, 2018.12.
2. Keisuke Tomohara, DMSO-perturbing assay for identifying promiscuous enzyme inhibitors, The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network (招待講演), 2018.09, Abstract: Nonspecific binding inhibitors of alpha-chymotrypsin, beta-lactamase, and hyaluronidase could be identified by the DMSO-perturbation assay..