Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Shinsuke Mizutani Last modified date:2024.03.31

Associate Professor / Department of Dental Science / Faculty of Dental Science


Papers
1. Shuge Gui, Junjun Ni, Shinsuke Mizutani, Norihiro Shigematsu, Hiroshi Nakanishi, Haruhiko Kashiwazaki, Hiro Take, A mixture of extracts from natural ingredients reduces the neurotoxic polarization of microglia via modulating NF-κB/NF-E2-related factor 2 activation, Food Science and Nutrition, 2024.03.
2. Mizutani Shinsuke, Hideaki Matsuzaki, Kiyomi Iyota, Asuka Tani, Saori Oku, Hiroaki Tabuchi, Akiko Fujiwara, Shizuka Hase-Tamaru, Hiro Kishimoto, Kenji Narazaki., Changes of Oral and Physical Functions in Older Japanese Who participated in Keyboard Harmonica and Exercise Classes during COVID-19-Related Movement Restrictions, International Journal of Environmental Research and Public Health, 10.3390/ijerph20043700, 20, 4, 3700, 2023.02.
3. Nanami Kai, Yoko Tsukamoto, Kaoru Urabe, Asuka Tani, Yuko Inai, Asako Okadome, Haruhiko Kashiwazaki, Shinsuke Mizutani, Naohisa Wada , Factors That Influence the Judgment of Oral Management Necessity in Preoperative Oral Screening, International Journal of Environmental Research and Public Health, 10.3390/ijerph182212236, 18, 22, 12236, 2021.11.
4. Muzhou Jiang, Xinwen Zhang, Xu Yan, Shinsuke Mizutani, Haruhiko Kashiwazaki, Junjun Ni, Zhou Wu, GSK3β is involved in promoting Alzheimer's disease pathologies following chronic systemic exposure to Porphyromonas gingivalis lipopolysaccharide in amyloid precursor protein NL-F/NL-F knock-in mice, Brain, Behavior, and Immunity, Online ahead of print., 2021.11.
5. Shinsuke Mizutani, Rui Egashira, Masahiro Yamaguchi, Keiko Tamai, Mizuki Yoshida, Tomotaka Kato, Yojiro Umezaki, Hisae Aoki, Toru Naito, Changes in oral and cognitive functions among older Japanese dental outpatients: A 2-year follow-up study, Journal of Oral Rehabilitation, Online ahead of print., 2021.07.
6. Kiyomi Iyota, Shinsuke Mizutani, Hiro Kishimoto, Saori Oku, Asuka Tani, Harukaze Yatsugi, Tianshu Chu, Xin Liu, Haruhiko Kashiwazaki, Effect of isometric tongue lifting exercise on oral function, physical function, and body composition in community-dwelling older individuals: a pilot study, Gerontology, in press, 2021.07.
7. Wanyi Huang, Fan Zeng, Yebo Gu, Muzhou Jiang, Xinwen Zhang, Xu Yan , Tomoko Kadowaki, Shinsuke Mizutani, Haruhiko Kashiwazaki, Junjun Ni, Zhou Wu, Porphyromonas Gingivalis Infection Induces Synaptic Failure via Increased IL-1β Production in Leptomeningeal Cells, Journal of Alzheimer's Disease, 10.3233/JAD-210031., 83, 2, 665-681, 2021.09.
8. Rui Egashira, Yojiro Umezaki, Shinsuke Mizutani, Toyoshi Obata, Masahiro Yamaguchi, Keiko Tamai, Mizuki Yoshida, Michiko Makino, Toru Naito, Relationship between cerebral atrophy and number of present teeth in elderly individuals with cognitive decline., Experimental Gerontology, 10.1016/j.exger.2020.111189, 144, 2021.02.
9. Rui Egashira, Shinsuke Mizutani, Masahiro Yamaguchi, Tomotaka Kato, Yojiro Umezaki, Saori Oku, Keiko Tamai, Toyoshi Obata, Toru Naito, Low Tongue Strength and the Number of Teeth Present Are Associated with Cognitive Decline in Older Japanese Dental Outpatients: A Cross-Sectional Study, International journal of environmental research and public health, https://doi.org/10.3390/ijerph17228700, 17, 20, 8700-8700, 2020.11.
10. Yoshihiro Kobayashi, Yuko Imai, Shinsuke Mizutani, Taiki Higo, Akira Shiose, Haruhiko Kashiwazaki, Opportune time of tooth extraction in individuals requiring ventricular assist device implantation: a retrospective cohort study, Journal of Oral and Maxillofacial Surgery, https://doi.org/10.1016/j.joms.2020.05.019, 78, 11, 1921.e1-1921.e9, 2020.11.
11. Kiyomi Iyota, Shinsuke Mizutani, Saori Oku, Misa Asao, Toshiko Futatsuki, Ryosuke Inoue, Yuko Imai, Haruhiko Kashiwazaki, A cross-sectional study of age-related changes in oral function in healthy Japanese individuals, International journal of environmental research and public health, 10.3390/ijerph17041376, 17, 4, 2020.02.
12. Yusuke Taniguchi, Kae Kakura, Takashi Tsutsumi, Kota Isshi, Hiromitsu Morita, Shinsuke Mizutani, Haruka Tohara, Hirofumi Kido , A study of the usefulness of implant superstructure production methods using optical impression systems and CAD/CAM techniques - targeting application during home visit dental treatment., Journal of interdisciplinary clinical dentistry, 1, 1, 2019.12, [URL].
13. Shinsuke Mizutani, Hisae Aoki, Satoru Haresaku, Kaoru Shimada, Michio Ueno, Keiko Kubota, Toru Naito, Association between subjective well-being and presence of primary care dentists in community-dwelling elderly people
A cross-sectional study, Gerodontology, 10.1111/ger.12390, 2019.01.
14. Kaoru Shimada, Hisae Aoki, Keiko Kubota, Satoru Haresaku, Shinsuke Mizutani, Toru Naito, Michio Ueno, Exceptional Association Rule Set Discovery from Community-dwelling Elderly People Database, 2018 IEEE International Conference on Systems, Man, and Cybernetics, 3285-3290, 2018.10, An extended method to discover exceptional association rule sets from incomplete databases is proposed. In an exceptional rule set, each itemset X, Y has a weak or no statistical relation to class C; however, the join of X and Y has a strong relation to C. An exceptional rule set can be used to infer long rules for the join of X and Y and to discover rare rules. The proposed method calculates the rule evaluation odds ratio directly. In this study, the method is applied to rule discovery using a database of community-dwelling elderly. Experimental results demonstrate that the proposed method can help discover interesting rare rules and exceptional association rule sets. The results show the effectiveness of the proposed method in the fields of medicine and health care..
15. Kaoru Shimada, Hisae Aoki, Keiko Kubota, Satoru Haresaku, Shinsuke Mizutani, Toru Naito, Michio Ueno, Exceptional Association Rule Set Discovery from Community-Dwelling Elderly People Database, 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018 Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018, 10.1109/SMC.2018.00558, 3295-3300, 2019.01.
16. Tomotaka Kato, Shinsuke Mizutani, Yojiro Umezaki, Seiichi Sugiyama, Toru Naito, Relationship between type D personality and dropout from dental treatment in middle-aged adults, Journal of Oral Science, 10.2334/josnusd.18-0068, 61, 2, 264-269, 2019.01.
17. Hirofumi Mizuno, Shinsuke Mizutani, Daisuke Ekuni, Ayano Tabata-Taniguchi, Takayuki Maruyama, Aya Yokoi, Chie Omori, Kazuyoshi Shimizu, Hiroshi Morimatsu, Yasuhiro Shirakawa, Manabu Morita, New oral hygiene care regimen reduces postoperative oral bacteria count and number of days with elevated fever in ICU patients with esophageal cancer, Journal of Oral Science, 10.2334/josnusd.17-0381, 60, 4, 536-543, 2018.12.
18. Naoki Toyama, Ayano Taniguchi-Tabata, Nanami Sawada, Yoshio Sugiura, Daiki Fukuhara, Yoko Uchida, Hisataka Miyai, Aya Yokoi, Shinsuke Mizutani, Daisuke Ekuni, Manabu Morita, Does Instruction of Oral Health Behavior for Workers Improve Work Performance?-Quasi-Randomized Trial, International Journal of Environmental Research and Public Health, 10.3390/ijerph15122630, 15, 12, 2018.11.
19. Shinsuke Mizutani, Daisuke Ekuni, Mayu Yamane-Takeuchi, Tetsuji Azuma, Ayano Taniguchi-Tabata, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Type D personality and periodontal disease in university students
A prospective cohort study, Journal of Health Psychology, 10.1177/1359105316668668, 23, 5, 754-762, 2018.04.
20. Some elderly patients who receive home-visit dental treatment do not use their newly fabricated dentures. The aim of this study was to investigate factors associated with non-use of newly fabricated dentures among elderly Japanese patients during home-visit dental treatment.

 In total, 108 patients received newly fabricated dentures in a private practice in Kumamoto prefecture from August 2012 to July 2013. The usage situation of the new dentures was recorded. Additional information obtained from medical records included age, sex, medical history, care need certification, oral state by Eichner's classification, and experience of wearing dentures prior to the manufacture of new dentures, which were compared between the denture use and denture non-use groups after the newly fabricated dentures were divided into upper jaw(n=88)or lower jaw(n=83)categories. Logistic regression analysis was performed with non-use of the newly fabricated dentures as a dependent variable and age, sex, experience of wearing dentures and care need certification as independent variables.

 Overall, 7 subjects(8.0%)did not use the newly fabricated dentures in the upper jaw and 7 subjects(8.4%)did not use them in the lower jaw. Among those who did not use the newly fabricated dentures, the percentage of subjects with no denture-wearing experience was 71.4% in the upper jaw and 85.7% in the lower jaw groups. Logistic regression analysis showed that no experience of wearing dentures was associated with non-use of the newly fabricated dentures during home-visit dental treatment after adjusting for age, sex, experience of wearing dentures and care need certification.

 These results suggest that no experience of wearing dentures is associated with a risk of non-use of newly fabricated dentures among elderly Japanese patients during home-visit dental treatment..

21. Tomotaka Kato, Shinsuke Mizutani, Hiroya Takiuchi, Seiichi Sugiyama, Takashi Hanioka, Toru Naito, Gingival pigmentation affected by smoking among different age groups
A quantitative analysis of gingival pigmentation using clinical oral photographs, International Journal of Environmental Research and Public Health, 10.3390/ijerph14080880, 14, 8, 2017.08.
22. Ayano Taniguchi-Tabata, Daisuke Ekuni, Shinsuke Mizutani, Mayu Yamane-Takeuchi, Kota Kataoka, Tetsuji Azuma, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Associations between dental knowledge, source of dental knowledge and oral health behavior in Japanese university students: A cross-sectional study, PLoS One, 10.1371/journal.pone.0179298, 12, 6, 2017.06.
23. Mayu Yamane-Takeuchi, Daisuke Ekuni, Shinsuke Mizutani, Kota Kataoka, Ayano Taniguchi-Tabata, Tetsuji Azuma, Michiko Furuta, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Associations among oral health-related quality of life, subjective symptoms, clinical status, and self-rated oral health in Japanese university students
A cross-sectional study, BMC Oral Health, 10.1186/s12903-016-0322-9, 16, 1, 2016.11.
24. Yuya Kawabata, Daisuke Ekuni, Hisataka Miyai, Kota Kataoka, Mayu Yamane, Shinsuke Mizutani, Koichiro Irie, Tetsuji Azuma, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Relationship between Prehypertension/Hypertension and Periodontal Disease
A Prospective Cohort Study, American Journal of Hypertension, 10.1093/ajh/hpv117, 29, 3, 388-396, 2016.03, nese university students..
25. Muneyoshi Kunitomo, Daisuke Ekuni, Shinsuke Mizutani, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Mayu Yamane, Kota Kataoka, Ayano Taniguchi-Tabata, Hirofumi Mizuno, Hisataka Miyai, Yoshiaki Iwasaki, Manabu Morita, Association between knowledge about comprehensive food education and increase in dental caries in Japanese university students
A prospective cohort study, Nutrients, 10.3390/nu8030114, 8, 3, 2016.02.
26. Shinsuke Mizutani, Daisuke Ekuni, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Yoshiaki Iwasaki, Manabu Morita, Self-efficacy and progression of periodontal disease
A prospective cohort study, Journal of Clinical Periodontology, 10.1111/jcpe.12476, 42, 12, 1083-1089, 2015.12.
27. Kota Kataoka, Daisuke Ekuni, Shinsuke Mizutani, Takaaki Tomofuji, Tetsuji Azuma, Mayu Yamane, Yuya Kawabata, Yoshiaki Iwasaki, Manabu Morita, Association between self-reported bruxism and malocclusion in university students
A cross-sectional study, Journal of Epidemiology, 10.2188/jea.JE20140180, 25, 6, 423-430, 2015.01.
28. Shinsuke Mizutani, D. Ekuni, T. Tomofuji, M. Yamane, T. Azuma, Y. Iwasaki, M. Morita, Gingival condition and tooth-brushing behavior after alcohol consumption, Journal of Periodontal Research, 10.1111/jre.12233, 50, 4, 494-499, 2015.01.
29. Shinsuke Mizutani, D. Ekuni, T. Tomofuji, T. Azuma, K. Kataoka, M. Yamane, Y. Iwasaki, M. Morita, Relationship between xerostomia and gingival condition in young adults, Journal of Periodontal Research, 10.1111/jre.12183, 50, 1, 74-79, 2015.01.
30. Tatsuya Machida, Takaaki Tomofuji, Daisuke Ekuni, Tetsuji Azuma, Noriko Takeuchi, Takayuki Maruyama, Shinsuke Mizutani, Kota Kataoka, Yuya Kawabata, Manabu Morita, Severe periodontitis is inversely associated with coffee consumption in the maintenance phase of periodontal treatment, Nutrients, 10.3390/nu6104476, 6, 10, 4476-4490, 2014.10.
31. Daisuke Ekuni, Toshiki Yoneda, Yasumasa Endo, Kenta Kasuyama, Koichiro Irie, Shinsuke Mizutani, Tetsuji Azuma, Takaaki Tomofuji, Manabu Morita, Occlusal disharmony accelerates the initiation of atherosclerosis in apoE knockout rats, Lipids in Health and Disease, 10.1186/1476-511X-13-144, 13, 1, 2014.09.
32. Daisuke Ekuni, Shinsuke Mizutani, Azusa Kojima, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Toshiki Yoneda, Michiko Furuta, Nobuoki Eshima, Yoshiaki Iwasaki, Manabu Morita, Relationship between increases in BMI and changes in periodontal status
A prospective cohort study, Journal of Clinical Periodontology, 10.1111/jcpe.12273, 41, 8, 772-778, 2014.08.
33. Shinsuke Mizutani, Daisuke Ekuni, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Yoshiaki Iwasaki, Manabu Morita, Structural equation modeling to assess gender differences in the relationship between psychological symptoms and dental visits after dental check-ups for university students, Acta Odontologica Scandinavica, 10.3109/00016357.2014.968870, 73, 5, 368-374, 2014.07.
34. Shinsuke Mizutani, Daisuke Ekuni, Takaaki Tomofuji, Tetsuji Azuma, Koichiro Irie, Tatsuya Machida, Toshiki Yoneda, Yoshiaki Iwasaki, Manabu Morita, Factors related to the formation of buccal mucosa ridging in university students, Acta Odontologica Scandinavica, 10.3109/00016357.2013.797102, 72, 1, 58-63, 2014.01.
35. Mayu Yamane, Daisuke Ekuni, Shinsuke Mizutani, Kota Kataoka, Masami Sakumoto-Kataoka, Yuya Kawabata, Chie Omori, Tetsuji Azuma, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Relationships between eating quickly and weight gain in Japanese University students
A longitudinal study, Obesity, 10.1002/oby.20842, 22, 10, 2262-2266, 2014.01, Objective: Many cross-sectional studies have reported a relationship between overweight/obesity and eating quickly, but there have been few longitudinal studies to address this relationship in younger populations. The purpose of this prospective longitudinal study was to investigate whether eating quickly was related to being overweight in Japanese university students. Methods: Of 1,396 students who underwent a general examination and completed questionnaires at the start of university and before graduation, 1,314 students (676 male and 638 female) of normal body composition [body mass index (BMI) -2] at baseline were included in the analysis. The questionnaires included speed of eating and other lifestyle factors. After a 3-year follow-up, the students whose BMIs were ≥25 kg m-2were defined as overweight. Results: In this study, 38 participants (2.9%) became overweight. In the logistic regression analysis, the risk of being overweight was increased in males [adjusted odds ratio (OR): 2.77; 95% confidence interval (CI): 1.33-5.79; P
36. Azusa Kojima, Daisuke Ekuni, Shinsuke Mizutani, Michiko Furuta, Koichiro Irie, Tetsuji Azuma, Takaaki Tomofuji, Yoshiaki Iwasaki, Manabu Morita, Relationships between self-rated oral health, subjective symptoms, oral health behavior and clinical conditions in Japanese university students
A cross-sectional survey at Okayama University, BMC Oral Health, 10.1186/1472-6831-13-62, 13, 1, 2013.11.
37. Daisuke Ekuni, Takaaki Tomofuji, Shinsuke Mizutani, Michiko Furuta, Koichiro Irie, Tetsuji Azuma, Azusa Kojima, Yoshiaki Iwasaki, Manabu Morita, Dental caries is correlated with knowledge of comprehensive food education in Japanese university students, Asia Pacific Journal of Clinical Nutrition, 10.6133/apjcn.2013.22.2.13, 22, 2, 312-318, 2013.04.
38. Daisuke Ekuni, Takaaki Tomofuji, Yasumasa Endo, Kenta Kasuyama, Koichiro Irie, Tetsuji Azuma, Naofumi Tamaki, Shinsuke Mizutani, Azusa Kojima, Manabu Morita, Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model, Archives of Oral Biology, 10.1016/j.archoralbio.2012.04.013, 57, 12, 1615-1622, 2012.12.
39. Shinsuke Mizutani, Daisuke Ekuni, Michiko Furuta, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Azusa Kojima, Jun Nagase, Yoshiaki Iwasaki, Manabu Morita, Effects of self-efficacy on oral health behaviours and gingival health in university students aged 18- or 19-years-old, Journal of Clinical Periodontology, 10.1111/j.1600-051X.2012.01919.x, 39, 9, 844-849, 2012.09.