| Makoto Yoritate | Last modified date：2022.06.29 |
Assistant Professor /
Go Hirai Group
Department of Chemo-Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences
Department of Chemo-Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences
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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/makoto-yoritate
Reseacher Profiling Tool Kyushu University Pure
http://sekkei.phar.kyushu-u.ac.jp/homeenglish/
The homepage of Go Hirai group .
Phone
092-642-6605
Fax
092-642-6605
Academic Degree
Bachelor Degree from Keio University, Facility of Science and Technology, Department of Applied Chemistry in March 10, 2013, Master Degree of Science from Keio University, Graduate School of Science and Technology in March 23, 2018, Ph'D Degree in Science from Keio University, Graduate School of Science and Technology in March 23, 2018
Country of degree conferring institution (Overseas)
No
Field of Specialization
Organic Synthetic Chemistry, Natural Product Chemistry, Organometallic Chemistry, Sugar Chemistry
ORCID(Open Researcher and Contributor ID)
0000-0003-2182-3914
Total Priod of education and research career in the foreign country
01years00months
Outline Activities
One of my research topics is the development of a new synthetic method of metabolically resistant C-glycoside and elucidation of its biological activity.
Especially, we are working on the development of a new drug discovery system (DDS) by using the self-assembly of glycolipids and prodrugs.
In addition, the synthesis and biological evaluation of pseudo-natural products are also of our interest.
Especially, we are working on the development of a new drug discovery system (DDS) by using the self-assembly of glycolipids and prodrugs.
In addition, the synthesis and biological evaluation of pseudo-natural products are also of our interest.
Research
Research Interests
Membership in Academic Society
- Development of Protecting-Group-Free C-Glycosylation
keyword : C-glycosylation, protecting-group-free, glycan, glycolipid
2022.03～2024.03. - "Synthesis and Biological Evaluation of Metabolically Stable C-Glycoside Analogues"
keyword : Saccharide, Lipid, Glycolipid, C-Glycoside
2019.04～2023.03. - "Structure-Activity Relationship of Pseudo-Natural Product Having Simplified Structure of Physalin-Type Natural Products"
keyword : Physalin B、Pseudo Natural Products、Structure-Activity Relationship
2020.03～2020.12.
Papers
| 1. | , [URL]. |
| 2. | Makoto Yoritate, Allyn T. Londregan, Yajing Lian, John F. Hartwig, Sequential Xanthalation and O-Trifluoromethylation of Phenols A Procedure for the Synthesis of Aryl Trifluoromethyl Ethers, Journal of Organic Chemistry, 10.1021/acs.joc.9b02717, 84, 24, 15767-15776, 2019.12. |
| 3. | Makoto Yoritate, Yoshito Takahashi, Hayato Tajima, Chisato Ogihara, Takashi Yokoyama, Yasuki Soda, Takeshi Oishi, Takaaki Sato, Noritaka Chida, Unified Total Synthesis of Stemoamide-Type Alkaloids by Chemoselective Assembly of Five-Membered Building Blocks, Journal of the American Chemical Society, 10.1021/jacs.7b10944, 139, 50, 18386-18391, 2017.12. |
| 4. | Makoto Yoritate, Tatsuhiko Meguro, Naoya Matsuo, Kenji Shirokane, Takaaki Sato, Noritaka Chida, Two-step synthesis of multi-substituted amines by using an N-methoxy group as a reactivity control element, Chemistry - A European Journal, 10.1002/chem.201402231, 20, 26, 8210-8216, 2014.06. |
Presentations
- THE SOCIETY OF CHEMICAL BIOLOGY, JAPAN
- THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
- THE CHEMICAL SOCIETY OF JAPAN
- Otsu Conference Award Fellow
- Unified Total Synthesis of Stemoamide-type Alkaloids Featuring Chemoselective Assembly of Five-membered Building Blocks
- Two-Step Synthesis of Multi-Substituted Amines and Unified Total Synthesis of Stemoamide-Type Alkaloids
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