Faculty Profiles - IMAJO IKUMI

Information

写真a

IMAJO IKUMI

Organization

Faculty of Dental Science Department of Dental Science Assistant Professor
Graduate School of Dental Science Department of Dental Science（Concurrent）
School of Dentistry Department of Dentistry（Concurrent）

Homepage

https://oral-maxillofacial.dent.kyushu-u.ac.jp/

External link

Research Areas

Life Science / Oral pathobiological science

Degree

Doctor of Philosophy （ 2012.3 Kyushu University ）

Research History

Kyushu University Faculty of Dental Science Department of Dental Science Assistant Professor

2019.9 - Present

Education

Kyushu University 歯学部歯学科

2001.4 - 2007.3

Research Interests・Research Keywords

Research theme： Analysis of the mechanism of multiple oral cancers.

Keyword： multiple oral cancer, Field cancerization

Research period： 2017.4

Papers

Dipeptidyl peptidase-4 inhibitor-related bullous pemphigoid diagnosed by oral manifestation

Yanai, Y; Kori, Y; Fujimoto, T; Imajo, I; Yanai, R; Yamada, T

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 35 ( 6 ) 528 - 533 2023.11 （ ISSN:2212-5558 eISSN:2212-5566 ）

　More details

Publisher：Journal of Oral and Maxillofacial Surgery Medicine and Pathology

There are numerous reports of bullous pemphigoid (BP) in patients taking dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes. However, reports of this phenomenon in the field of dentistry and oral surgery are rare. We report a case of DPP-4- inhibitor-related BP (DPP-4i-BP) diagnosed via oral manifestation. The patient was a 64-year-old woman who had experienced itching, redness, and blisters on her head and lower limbs for three months on initial examination. One month later, she developed blisters on her gums and was examined at our department. The patient had a history of type 2 diabetes and was taking teneligliptin. She presented with blisters and erosions on her gums, and erythema on the skin of the upper limbs and pelvic region. Two weeks later, the patient presented with firm, full blisters on her skin, and aggravated erosion of her oral mucosa. Biopsy of the oral mucosa and skin revealed subepithelial blistering; direct immunofluorescence confirmed IgG and complement deposits along the epidermal basement membrane. DPP-4i-BP was suspected. DPP-4i was stopped, and the patient began a course of oral nicotinamide and doxycycline and topical steroids. Her antibody titre decreased, and her symptoms improved. However, two months after the start of treatment, she presented with a new blister on her skin and began a course of low-dose oral steroids. One month later, the new blister had resolved. Erosion of the oral mucosa subsequently resolved, and topical steroids were stopped. The use of oral steroids was decreased, and no recurrence was observed.

DOI： 10.1016/j.ajoms.2023.03.007

Web of Science

Scopus
Mandibular metastasis from prostate cancer that clinically mimicked osteosarcoma: a case report Reviewed International journal

Ikumi Imajo, Tomohiro Yamada, Takahiro Fujinaga, Koki Nagano, Wataru Kumamaru, Yuta Yanai, Toru Chikui, Tamotsu Kiyoshima.

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 35 ( 5 ) 445 - 449 2023.9

　More details

Language：English Publishing type：Research paper (scientific journal)

Repository Public URL： https://hdl.handle.net/2324/7174354
Mandibular metastasis from prostate cancer that clinically mimicked osteosarcoma: A case report

Imajo, I; Yamada, T; Fujinaga, T; Nagano, K; Kumamaru, W; Yanai, Y; Chikui, T; Kiyoshima, T

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY 35 ( 5 ) 445 - 449 2023.9 （ ISSN:2212-5558 eISSN:2212-5566 ）

　More details

Publisher：Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Metastatic tumors in the oral cavity are rare, accounting for only 1% of all oral malignancies. The most common site of metastatic tumors in the oral cavity is the mandibular molar region. The primary sites differ between the sexes. Among men, the primary sites are the lung, kidney, liver, and prostate in the order of frequency. Moreover, 11% of jawbone metastases among men originate from the prostate gland. Symptoms differ according to the location of the metastasis; besides, metastases-related imaging findings are nonspecific, making it difficult to reach an accurate diagnosis. Metastatic oral cancer has a poor prognosis; therefore, early diagnosis and treatment are important to improve the survival-rate and quality of life. A 76-year-old male patient was referred to our hospital with complaint of right-sided mandibular swelling and past medical history of adenocarcinoma of the prostate gland. Intraoral examination revealed a hard hemispherical mass on the right mandibular first molar region. Computed tomography showed a well-marginated radiopaque hemisphere mass with a typical sunburst periosteal reaction. Based on the imaging findings, we suspected primary osteosarcoma or metastatic prostate cancer. Histopathological examination of the mandible revealed a glandular structure with atypia similar to that of the primary prostate cancer cells. After prostate specific antigen monitoring therapy, the metastatic cancer did not grow. Metastatic cancers from other organs should be considered in the differential diagnosis of jawbone malignancies because the metastatic cancer might present similarities to the primary cancer in imaging findings, as in the present case that clinically mimicked osteosarcoma.

DOI： 10.1016/j.ajoms.2023.01.009

Web of Science

Scopus
Intraosseous synovial sarcoma of the mandible: A case report and review of the literature

Imajo Ikumi, Yamada Tomohiro, Chikui Toru, Kiyoshima Tamotsu, Ito Mamoru, Kohashi Kenichi, Sakamoto Eiji, Oda Yoshinao

Oncology Letters 26 ( 1 ) 318 2023.6 （ ISSN:17921074 eISSN:17921082 ）

　More details

Language：English Publisher：Spandidos Publications

Synovial sarcoma (SS) is a malignant soft tissue tumor that usually arises in the para‑articular regions of the extremities. Only nine cases of SS in the mandible have been reported to date. The present study described a case of SS arising from the left mandible. A 54‑year‑old woman was referred to Kyushu University Hospital (Fukuoka, Japan) with a complaint of numbness in the left mental nerve area. Computed tomography revealed replacement of the left mandibular bone marrow with soft tissue and destruction of the mandibular canal. Magnetic resonance imaging revealed an isointense mass on T1‑weighted images and hyperintensity on T2‑weighted images. The tumor showed homogeneous enhancement. A biopsy was performed, and monophasic SS was diagnosed based on immunohistochemical staining features and genetic analysis. Hemimandible dissection and supraomophyoid neck resection were performed with fibular osteocutaneous flap reconstruction, followed by adjuvant chemotherapy. There was no evidence of recurrence or distant metastases. The present study also reviewed the clinical, imaging, histological, and immunohistochemical features of the SS in the mandible.

DOI： 10.3892/ol.2023.13904

Web of Science

Scopus

PubMed

CiNii Research
Dipeptidyl peptidase-4 inhibitor-related bullous pemphigoid diagnosed by oral manifestation Reviewed International journal

Yuta Yanai, Yuriko Kori, Tatsufumi Fujimoto, Ikumi Imajo, Risa Yanai, Tomohiro Yamada

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 35 ( 6 ) 528 - 533 2023.4

　More details

Language：English Publishing type：Research paper (scientific journal)
Methotrexate-associated lymphoproliferative disorder affecting the gingiva and intestinal mucosa with intestinal perforation: A case report Reviewed International journal

Takahiro Fujinaga, Yukiko Ohyama, Koki Nagano, Ikumi Imajo, Tomohiro Yamada, Tamotsu Kiyoshima, Yoshihide Mori

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 34 ( 2 ) 169 - 173 2022.3

　More details

Language：English Publishing type：Research paper (scientific journal)
Methotrexate-associated lymphoproliferative disorder affecting the gingiva and intestinal mucosa with intestinal perforation: A case report

Fujinaga, T; Ohyama, Y; Nagano, K; Imajo, I; Yamada, T; Kiyoshima, T; Mori, Y

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY 34 ( 2 ) 169 - 173 2022.3 （ ISSN:2212-5558 eISSN:2212-5566 ）

　More details

Publisher：Journal of Oral and Maxillofacial Surgery Medicine and Pathology

According to the fourth revised edition of the world health organization classification of hematopoietic tumors, methotrexate (MTX)-associated lymphoproliferative disorder (MTX-LPD), an atypical pathological condition, is categorized under other iatrogenic immunodeficiency-associated lymphoproliferative disorders (OIIA-LPDs). An 80-year-old woman presented with OIIA-LPDs that simultaneously occurred in the gingiva and intestinal mucosa, causing intestinal perforation requiring emergency surgery. She was referred to our hospital because of poor wound healing after maxillary right first molar extraction. She had been prescribed MTX and prednisolone for rheumatoid arthritis and bisphosphonate for osteoporosis. We diagnosed her with medication-related osteonecrosis of the jaw, as the lesion showed bone exposure with mild redness and swelling of the surrounding gingiva and a cytological result of Class II. However, 9 months later, following the exfoliation of a partial sequestrum of the maxillary right first molar, a rapidly growing mass with gingival necrosis appeared, necessitating a biopsy. Simultaneously, abdominal pain worsened, and computed tomography revealed intestinal perforation; an emergency laparotomy was performed to remove the perforation and the surrounding ulcer-prone area. Histopathological examination of both lesions revealed diffuse large B-cell lymphomas. The final diagnosis was of MTX-LPD, as the mass, gingival necrosis, and residual small intestinal ulcer disappeared 2 months after MTX discontinuation. The exposed bone completely disappeared after 24 months, and no recurrence was noted after 60 months following MTX discontinuation. Although intestinal perforation due to MTX-LPD is extremely rare, patients with RA are immunosuppressed. Therefore, MTX-LPD must be recognized as a dangerous condition that requires careful general monitoring in such patients.

DOI： 10.1016/j.ajoms.2021.08.012

Web of Science

Scopus
下顎歯肉に生じた結核症の1例 Reviewed

定成未来、熊丸　渉、石井広太郎、今城育美、清島　保、森　悦秀

日本口腔外科学会雑誌 67 ( 12 ) 703 - 710 2021.12

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
口腔症状を主症状としたクローン病の1例 Reviewed

石井広太郎, 室屋龍祐, 大山順子, 今城育美, 清島　保, 森　悦秀.

日本口腔外科学会雑誌 66 ( 12 ) 627 - 632 2020.12

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
顎口腔領域に発生した悪性リンパ腫の臨床的検討 Reviewed

今城育美, 山田朋弘, 大山順子, 石井広太郎, 森悦秀

日本口腔科学会雑誌 68 ( 3 ) 212 - 219 2019.10

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
Maxillofacial fractures caused by falls. Reviewed International journal

Ikumi Imajo, Tomohiro Yamada, Kotaro Ishii, Tomohiko Akahoshi, Kenta Momii, Ken-ichi Kamizono, Tomoki Sumida and Yoshihide Mori.

Clinics in Surgery. 2019.2

　More details

Language：English Publishing type：Research paper (scientific journal)

Repository Public URL： https://hdl.handle.net/2324/7324206
下顎枝矢状分割術による下顎前方移動後に生じた末梢性顔面神経麻痺の1例 Reviewed

今城育美, 木附智子, 中野旬之, 山城崇裕, 碇竜也, 森悦秀

日本口腔外科学会雑誌 64 ( 4 ) 207 - 212 2018.4

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
基底細胞母斑症候群を伴うAngle Class I叢生成人女性症例 Reviewed

二階堂まりこ, 星健治, 今城育美, 山田朋弘, 森悦秀, 高橋一郎

九州矯正歯科学会雑誌 13 ( 1 ) 16 - 22 2018.3

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
Expression levels　of　SOX2,　KLF4　and　brachyury　trasscription　factors　are　associated　with　metastasis　and　poor　prognosis in oral squamous cell carcinoma. Reviewed International journal

Yoshihama R, Yamaguchi K, Imajyo I, Mine M, Hiyake N, Akimoto N, Kobayashi Y, Chigita　S, Kumamaru W, Kiyoshima T, Mori Y, Sugiura T

Oncol Lett 11(2): 1435-1446, 2016. 2016.2

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
Knockdown of the T-box transcription factor Brachyury increase sensitivity of adenoid cystic carcinoma cells to chemotherary and radiation in vitro: implications for a new therapeutic principle. Reviewed International journal

Kobayashi Y, Sugiura T, Imajyo I, Shimoda M, Ishii K, Akimoto N, Yoshihama N, Mori Y.

Int J Oncol 44(4):1107-17, 2014. 2014.2

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
口唇にみられた血管内乳頭状内皮過形成(IPEH)の2例 Reviewed

今城育美, 窪田泰孝, 大山順子, 碓井智也, 佐々木匡理, 竹之下康治

日本口腔科学会雑誌 13 ( 1 ) 228 - 233 2013.7

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
Effects of the patient's age and the size of the primary lesion on the speed of shrinkage after marsupialisation of keratocystic odontogenic tumours, dentigerous cysts, and radicular cysts. Reviewed International journal

Kubota Y, Imajo I, Itonaga R, Takenoshita Y.

Br J Oral Maxillofac Surg. 51 ( 4 ) 358 - 362 2013.6

　More details

Language：English Publishing type：Research paper (scientific journal)
T-Box transcription factor Brachyury expression is correlated with epitherial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma. Reviewed International journal

Imajyo I, Sugiura T, Kobayashi Y, Shimoda M, Ishii K, Akimoto N, Yoshihama N, Kobayashi I, Mori Y.

Int J Oncol. 41 ( 6 ) 1985 - 1995 2012.12

　More details

Language：English Publishing type：Research paper (scientific journal)
The T-box transcription factor Brachury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells. Reviewed International journal

Shimoda M, *Sugiura T, Imajyo I, Ishii K, Chigita S, Seki K, Kobayashi Y, Shirasuna K.

BMC Cancer 377, 2012. 2012.8

　More details

Language：Japanese Publishing type：Research paper (scientific journal)
Retorospective study of selective submandibular neck dissection versus radical neck dissection for N0 or N1 necks in levelⅠ patients with oral squamous cell carcinoma. Reviewed International journal

Yanai Y, *Sugiura T, Imajyo I, Yoshihama N, Akimoto N, Kobayashi Y, Hayashi K, Fujinaga K, Takenoshita Y, Mori Y.

J Oncol 634183, 2012. 2012.5

　More details

Language：Japanese Publishing type：Research paper (scientific journal)

▼display all

Books

救急＆アクシデント対応ハンドブック

森悦秀、山田朋弘、大山順子、熊丸渉、杉山悟郎、矢内雄太、石井広太郎一杉岳、横山武志、柏﨑晴彦、三島克章、今城育美、鎌田裕、長野公喜木附智子、吉濱直哉、和田尚久、中島康経、南克浩、中野旬之、住田和樹、藤永貴大,

医歯薬出版 2022.3

　More details

Language：Japanese

Presentations

A case of mandibular prognathism associated with acromegaly treated with glossectomy, maxillary distraction osteogenesis, and bilateral sagittal split

藤永貴大,今城育美,澁谷南,今利一寿,安田光佑,塩川裕之,寺尾文恵,山田朋弘,髙橋一郎,森山雅文

第35回特定非営利活動法人日本顎変形症学会総会・学術大会 2025.6

　More details

Event date： 2025.6
頸部リンパ節後発転移と成人T細胞白血病リンパ腫を合併した1症例

今城育美, 熊丸渉, 山田朋弘 , 川野真太郎, 清島保 , 森山雅文

第43回日本口腔腫瘍学会総会・学術大会 2025.2

　More details

Event date： 2025.2
下顎皮質骨を含めた腫瘍切除術に対する工夫

熊丸渉, 今城育美, 藤永貴大, 藤本龍史, 清島保, 川野真太郎, 森山雅文

第43回日本口腔腫瘍学会総会・学術大会 2025.2

　More details

Event date： 2025.2
上下顎骨切り術後の出血から迷走神経、副神経、舌下神経麻痺に至った一例

安井涼馬、今利一寿、今城育美、澁谷南、藤永貴大、杉山悟郎、山田朋弘、森山雅文

若手口腔外科医交流会第2回学術集会 2024.5

　More details

Event date： 2024.5
粘膜下口蓋裂の臨床的検討

森信美紀,田尻姿穂,長谷川幸代,吉濱るみ,今城育美,杉山悟郎,大山順子,山田朋弘

第47回　日本口蓋裂学会総会・学術大会 2023.5

　More details

Event date： 2023.5

Language：Japanese

Venue：東京 Country：Japan
相同モデルを用いた就学前口唇裂術後患者に対する形態評価と修正術後の予測

澁澤伸英, 安田光佑, 田尻姿穂, 森信美紀, 吉濱るみ, ⾧野公喜,藤永貴大, 吉濱直哉, 今城育美, 杉山悟郎, 大山順子, 山田朋弘

第47回　日本口蓋裂学会総会・学術大会 2023.5

　More details

Event date： 2023.5

Language：Japanese

Venue：東京 Country：Japan
全身麻酔下での消炎処置を要した歯性感染症についての臨床的検討

藤本龍史、今城育美、秋山史織、吉濱直哉、矢内雄太、杉山悟郎、熊丸渉、山田朋弘

第77回　日本口腔科学会学術集会 2023.5

　More details

Event date： 2023.5

Language：Japanese

Venue：岡山 Country：Japan
翼突下顎隙に進展した歯原性角化嚢胞の3例

水田修平、今城育美、藤永貴大、大山順子、山田朋弘、森　悦秀

第66回日本口腔外科学会総会・学術大会 2021.11

　More details

Event date： 2022.11

Language：Japanese

Venue：幕張 Country：Japan
TruMatch®システムを用いた遊離腓骨皮弁下顎骨再建の臨床的評価

澁谷南, 杉山悟郎, 鎌田裕，熊丸渉，今城育美, 吉濱直哉，木附智子, 山田朋弘

第90回日本口腔外科学会九州支部学術集会 2022.6

　More details

Event date： 2022.6
口腔癌患者における同時性重複癌の臨床的検討

竹田早希、矢内雄太、今城育美、藤永貴大、熊丸　渉、山田朋弘、森　悦秀

第76回　日本口腔科学会総会 2022.4

　More details

Event date： 2022.4 - 2022.5

Language：Japanese

Venue：福岡 Country：Japan
薬剤関連顎骨壊死による疼痛に対して下顎神経ブロックを行った一例

今城育美、大山順子、山田朋弘、藤永貴大、長野公喜、矢内雄太、石井広太郎、今利一寿、木附智子、森　悦秀

第25回　口腔顔面神経機能学会総会・学術大会 2022.2

　More details

Event date： 2022.2

Language：Japanese

Venue：WEB開催 Country：Japan
顎関節強直症の再発に対して下顎頭付再建用プレートを使用し授動術を行った1例

小見山琢麻, 今城育美, 石井広太郎, 山田朋弘, 森　悦秀.

第89回日本口腔外科学会九州支部学術集会 2021.5

　More details

Event date： 2021.5

Language：Japanese

Venue：WEB開催 Country：Japan
顎裂患者に対する粘膜移植を併用した口腔前庭拡張術の有用性

炭本雄基, 山田朋弘, 吉濱直哉, 大山順子, 杉山悟郎, 今城育美, 田尻姿穂, 鎌田裕, 春山直人, 野村俊介, 野口健志 , 高橋一郎, 森　悦秀

第45回日本口蓋裂学会総会・学術集会 2021.5

　More details

Event date： 2021.5

Language：Japanese

Country：Japan
下顎骨に発生した滑膜肉腫の一例

塩山理子, 今城育美, 藤永貴大, 清島　保, 山田朋弘.

第39回日本口腔腫瘍学会総会・学術大会 2021.1

　More details

Event date： 2021.1 - 2021.2

Language：Japanese

Venue：WEB開催 Country：Japan
多発および再発性口腔癌の臨床的検討

今城育美 ,山田朋弘, 石井広太郎, 熊丸渉, 森悦秀

第88回　日本口腔外科学会九州支部学術集会 2020.8

　More details

Event date： 2020.8

Language：Japanese

Country：Japan
口腔悪性腫瘍組織におけるT-box転写因子Brachyuryの発現と上皮間葉移行の関与

今城育美, 杉浦剛, 石井広太郎, 下田みゆき, 小林洋輔, 秋本直柔, 吉濱直哉, 小林家吉, 森悦秀

第65回日本口腔科学会総会 2011.4

　More details

Event date： 2020.4 - 2011.4

Language：Japanese

Venue：東京　タワーホール船堀 Country：Japan
口腔扁平上皮癌の再発に関する臨床的検討

今城育美,山田朋弘,石井広太郎,矢内雄太,清島保,森悦秀

第64回日本口腔外科学会総会 2019.10

　More details

Event date： 2019.10

Language：Japanese

Venue：北海道　札幌（札幌コンベンションセンター） Country：Japan
Clinicopathological study of oral multiple cancer. International conference

Ikumi Imajo, Tomohiro Yamada, Kotaro Ishii,Tomoki Sumida, Wataru Kumamaru, Tamotsu Kiyoshima, Yoshihide Mori.

Asian Congress on Oral & Maxillofacial surgery 2018.11

　More details

Event date： 2018.11

Language：English

Venue：Taiwan Taipei Country：Taiwan, Province of China
口腔多発腫瘍周囲上皮組織のField形成に関する臨床病理組織学的検討

今城育美, 山田朋弘,石井広太郎, 小倉綾乃, 清島保,森悦秀

第63回日本口腔外科学会総会 2018.11

　More details

Event date： 2018.11 - 2020.11

Language：Japanese

Venue：千葉　幕張（幕張メッセ） Country：Japan
舌下腺癌術後に発症した肺血栓塞栓症の一例

竹下祐香里今城育美馬場寛一石井広太郎住田知樹山田朋弘森悦秀

第86回日本口腔外科学会九州支部学術集会 2018.6

　More details

Event date： 2018.6 - 2021.6

Language：Japanese

Venue：福岡 Country：Japan
当科における口腔多発腫瘍の臨床病理組織学的検討

今城育美, 山田朋弘, 石井広太郎, 小倉綾乃, 清島保, 森悦秀

第72回日本口腔科学会総会 2018.5

　More details

Event date： 2018.5

Language：Japanese

Venue：愛知　名古屋（ウインク愛知） Country：Japan
当科における口腔扁平上皮癌一次症例の臨床統計学的検討

小倉綾乃今城育美熊丸　渉石井広太郎大山順子住田知樹山田朋弘

第36回日本口腔腫瘍学会総会 2018.1

　More details

Event date： 2018.1

Language：Japanese

Venue：新潟 Country：Japan
当科におけるエナメル上皮腫の治療法と再発に関する臨床的検討

田尻姿穂山田朋弘石井広太郎今城育美熊丸　渉大山順子住田知樹清島　保森　悦秀

第36回日本口腔腫瘍学会総会 2018.1

　More details

Event date： 2018.1

Language：Japanese

Country：Japan
高所墜落外傷における顎顔面領域骨折の検討

今城育美, 石井広太郎, 赤星朋比古, 山田朋弘

第19回日本口腔顎顔面外傷学会 2017.7

　More details

Event date： 2017.7

Language：Japanese

Venue：北海道　札幌（手稲渓仁会病院） Country：Japan
顎口腔領域に初発症状を呈した悪性リンパ腫の臨床的検討

今城育美、大山順子、熊丸渉、石井広太郎、住田知樹、山田朋弘、森悦秀

第35回口腔腫瘍学会総会 2017.1

　More details

Event date： 2017.1

Language：Japanese

Venue：福岡（福岡国際会議場） Country：Japan
切歯管嚢胞の開窓効果

今城育美、窪田泰孝、碇竜也、森悦秀

第45回口腔科学会九州地方会 2012.11

　More details

Event date： 2012.11

Language：Japanese

Venue：福岡　福岡（福岡大学病院） Country：Japan
口腔悪性腫瘍組織におけるT-box転写因子Brachyuryの発現と上皮間葉移行の関与

今城育美, 杉浦剛, 小林洋輔, 吉濱直哉, 秋本直柔, 森悦秀

第57回日本口腔外科学会総会 2012.10

　More details

Event date： 2012.10

Language：Japanese

Venue：神奈川　横浜（パシフィコ横浜） Country：Japan
The clinicopathological relation between Brachyury and epithelial-mesenchymal transition (EMT) in oral cancer.

今城育美, 杉浦剛, 小林洋輔, 吉濱直哉, 秋本直柔, 森悦秀

第70日本癌学会学術総会 2011.10

　More details

Event date： 2011.10

Language：English

Venue：愛知　名古屋（名古屋国際会議場） Country：Japan
歯原性顎骨嚢胞の開窓効果

今城育美, 二宮史浩, 窪田泰孝, 岡正司, 山城崇裕, 陶山曜子, 矢原佳枝, 竹之下康治

第54回日本口腔外科学会総会 2009.10

　More details

Event date： 2009.10

Language：Japanese

Venue：北海道　札幌（札幌コンベンションセンター） Country：Japan
基底細胞母斑症候群の16例

今城育美, 二宮史浩, 窪田泰孝, 岡正司, 山城崇裕, 陶山曜子, 矢原佳枝, 竹之下康治

第54回日本口腔外科学会総会 2009.10

　More details

Event date： 2009.10

Language：Japanese

Venue：北海道　札幌（札幌コンベンションセンター） Country：Japan
下口唇に発生した血管内乳頭状過形成の一例

今城育美, 竹之下康治, 佐々木匡理, 大山順子, 碇竜也, 杉友貴, 坂井英隆, 白砂兼光

第27回口腔腫瘍学会総会 2009.1

　More details

Event date： 2009.1

Language：Japanese

Venue：栃木　宇都宮 Country：Japan
顎矯正手術後の咬合異常に対し外科的介入を要した症例の検討

山田朋弘, 藤永貴大, 今城育美, 杉山悟郎, 長野公喜, 澁谷南, 吉濱直哉, 田尻姿穂, 澁澤伸英, 吉濱るみ, 森信美紀, 大山順子, 森悦秀, 高橋一郎

日本顎変形症学会雑誌 2023.5 (NPO)日本顎変形症学会

　More details

Language：Japanese
顎矯正手術後に気胸を生じた1例

安井涼馬, 長野公喜, 澁谷南, 藤永貴大, 今城育美, 杉山悟郎, 大山順子, 山田朋弘

日本顎変形症学会雑誌 2023.5 (NPO)日本顎変形症学会

　More details

Language：Japanese
ハイブリッド相同モデルによる顎矯正手術前後の硬・軟組織形態変化の3次元的検討

澁澤伸英, 藤永貴大, 蒲原英恵, 森信美紀, 安田光佑, 田尻姿穂, 澁谷南, 今城育美, 杉山悟郎, 大山順子, 森山雅文, 山田朋弘

日本顎変形症学会雑誌 2024.5 (NPO)日本顎変形症学会

　More details

Language：Japanese
遠隔言語訓練における音声信号の歪みに関する音響学的評価

田尻姿穂, 大山順子, 森信美紀, 吉濱るみ, 今城育美, 杉山悟郎, 山田朋弘

日本口腔科学会雑誌 2023.7 (NPO)日本口腔科学会

　More details

Language：Japanese
粘膜下口蓋裂の臨床的検討

森信美紀, 田尻姿穂, 長谷川幸代, 吉濱るみ, 今城育美, 杉山悟郎, 大山順子, 山田朋弘

日本口蓋裂学会雑誌 2023.4 (一社)日本口蓋裂学会

　More details

Language：Japanese
相同モデルを用いた就学前口唇裂術後患者に対する形態評価と修正術後の予測

澁澤伸英, 田尻姿穂, 安田光佑, 森信美紀, 吉濱るみ, 長野公喜, 藤永貴大, 吉濱直哉, 今城育美, 杉山悟郎, 大山順子, 山田朋弘

日本口蓋裂学会雑誌 2023.4 (一社)日本口蓋裂学会

　More details

Language：Japanese
口腔癌患者における同時性重複癌の臨床的検討

竹田早希, 矢内雄太, 今城育美, 藤永貴大, 熊丸渉, 山田朋弘, 森悦秀

日本口腔科学会雑誌 2022.7 (NPO)日本口腔科学会

　More details

Language：Japanese
全身麻酔下での消炎処置を要した歯性感染症についての臨床的検討

藤本龍史, 今城育美, 秋山史織, 吉濱直哉, 矢内雄太, 杉山悟郎, 熊丸渉, 山田朋弘

日本口腔科学会雑誌 2023.7 (NPO)日本口腔科学会

　More details

Language：Japanese

▼display all

Professional Memberships

日本顎変形症学会
日本口蓋裂学会
日本口腔腫瘍学会
日本口腔科学会
日本口腔外科学会

Research Projects

Effects of genomic / epigenomic abnormalities on field formation in oral multiple cancers

Grant number：19K19164 2019 - 2022

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Early-Career Scientists

今城育美

　 More details

Authorship：Principal investigator Grant type：Scientific research funding

多発腫瘍の発症は Field cancerization（広域発癌）（Slaughter, 1953）の概念で説明され、近年の分子研究の発展によりメカニズムは分子学的に解明されつつある。しかし、治療への応用には至っておらず、生存率の向上もみられていない。本研究では、Field 形成と発癌に関与しうるゲノム不安定性およびエピジェネティック異常に着目し、口腔多発癌症例の臨床検体より Field cancerization の発症機構を解析する。

CiNii Research
口腔多発癌の変異細胞不均一性とエピジェネティック異常の検討

Grant number：17K17260 2017 - 2019

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists(A)or(B)

　 More details

Authorship：Principal investigator Grant type：Scientific research funding

Educational Activities

学部生に対する臨床予備実習、臨床実習における教育、指導を担当している。

Class subject

口腔外科臨床予備実習

2025.6 - 2025.7 First semester
顎口腔外科学

2024.10 - 2025.1 Second semester
臨床予備実習

2023.4 - 2023.9 First semester
歯科臨床予備実習

2020.4 - 2020.9 First semester
アーリーエクスポージャ

2020.4 - 2020.9 First semester
歯科臨床実習

2019.10 - 2020.3 Second semester

▼display all

FD Participation

2019.9 Role：Participation Title：「科研費申請のススメ！～科学研究費補助金制度と研究計画調書作成時の注意点～」

Organizer：[Undergraduate school/graduate school/graduate faculty]

Outline of Social Contribution and International Cooperation activities

ベトナムの口唇口蓋裂患者の治療および医療スタッフの教育を行い、医療援助活動を行っている。

Social Activities

ベトナム（ニンビン省）で口唇口蓋裂患者に対する医療支援

2019.3

Specialized clinical area

Biology / Medicine, Dentistry and Pharmacy / Dentistry / Surgical Dentistry

Clinician qualification

Certifying physician

日本口腔外科学会
Specialist

日本口腔外科学会
Certifying physician

日本口腔科学会
Certifying physician

日本がん治療医認定機構　がん治療認定医（歯科口腔外科）

Year of medical license acquisition

2007