Kyushu University Academic Staff Educational and Research Activities Database
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Taichi Isobe Last modified date:2021.07.15



Graduate School
Undergraduate School
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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/taichi-isobe
 Reseacher Profiling Tool Kyushu University Pure
Academic Degree
Ph.D.
Field of Specialization
Cancer Biology, Stem Cell Biology, Oncology
ORCID(Open Researcher and Contributor ID)
https://orcid.org/0000-0001-5686-1940
Total Priod of education and research career in the foreign country
06years06months
Outline Activities
Basic and clinical research
Clinical service
Research
Research Interests
  • Characterization of immune responses in tumor mecroenvironment of patients with clonal hematopoiesis
    keyword : Clonal hematopoiesis, Cancer, Microenvironment
    2021.04.
  • Establishment of a new model for human colorectal cancers
    keyword : Cancer, Chromosome abnormalities
    2019.04.
Academic Activities
Papers
1. Tabula Muris Consortium, A single-cell transcriptomic atlas characterizes ageing tissues in the mouse, Nature, 10.1038/s41586-020-2496-1, 583, 7817, 590-595, 2020.07.
2. Junko Mukohyama, Taichi Isobe, Qingjiang Hu, Takanori Hayashi, Takashi Watanabe, Masao Maeda, Hisano Yanagi, Xin Qian, Kimihiro Yamashita, Hironobu Minami, Koshi Mimori, Debashis Sahoo, Yoshihiro Kakeji, Akira Suzuki, Piero Dalerba, Yohei Shimono, miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells., Cancer research, 10.1158/0008-5472.CAN-18-3544, 79, 20, 5151-5158, 2019.10.
3. Tabula Muris Consortium, Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris., Nature, 10.1038/s41586-018-0590-4, 562, 367-372, 2018.10.
4. Tamura S, Isobe T, Ariyama H, Nakano M, Kikushige Y, Takaishi S, Kusaba H, Takenaka K, Ueki T, Nakamura M, Akashi K, Baba E, E‑cadherin regulates proliferation of colorectal cancer stem cells through NANOG., Oncology reports, 10.3892/or.2018.6464, 40, 2, 693-703, 2018.08.
5. Taichi Isobe, Shigeo Hisamori, Daniel J. Hogan, Maider Zabala, David G. Hendrickson, Piero Dalerba, Shang Cai, Ferenc Scheeren, Angera H. Kuo, Shaheen S. Sikandar, Jessica S. Lam, Dalong Qian, Frederick M. Dirbas, George Somlo, Kaiqin Lao, Patrick O. Brown, Michael F. Clarke, Yohei Shimono, miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway, ELIFE, 10.7554/eLife.01977, 3, 2014.11.
6. Taichi Isobe, Keita Uchino, Chinatsu Makiyama, Hiroshi Ariyama, Shuji Arita, Shingo Tamura, Masato Komoda, Hitoshi Kusaba, Tsuyoshi Shirakawa, Taito Esaki, Kenji Mitsugi, Shigeo Takaishi, Koichi Akashi, Eishi Baba, Analysis of Adverse Events of Bevacizumab-containing Systemic Chemotherapy for Metastatic Colorectal Cancer in Japan, ANTICANCER RESEARCH, 34, 4, 2035-2040, 2014.04.
7. Taichi Isobe, Eishi Baba, Shuji Arita, Masato Komoda, Shingo Tamura, Tsuyoshi Shirakawa, Hiroshi Ariyama, Shigeo Takaishi, Hitoshi Kusaba, Takashi Ueki, Koichi Akashi, Human STEAP3 maintains tumor growth under hypoferric condition, EXPERIMENTAL CELL RESEARCH, 10.1016/j.yexcr.2011.07.022, 317, 18, 2582-2591, 2011.11.
8. Isobe T, Yanai S, Kusaba H, Yada S, Kuroda Y, Tamiya S, Matsumoto T, Baba E, Harada M, Effective monotherapy with amrubicin for a refractory extrapulmonary small-cell carcinoma of the liver., Case reports in medicine, 10.1155/2009/538081, 2009, 538081, 2009.06.
9. T Isobe, TE Tanimoto, G Nakaji, T Miyamoto, S Yamasaki, K Takase, A Numata, T Fukuda, K Nagafuji, S Inaba, M Harada, Autoimmune thrombocytopenia with clonal expansion of CD8-positive T cells after autologous peripheral blood stem cell transplantation for diffuse large B-cell lymphoma, BONE MARROW TRANSPLANTATION, 10.1038/sj.bmt.1704750, 35, 3, 315-316, 2005.02.
Membership in Academic Society
  • The Japanese Society of Gastroenterology
  • Japanese Society of Medical Oncology
  • Japanese Cancer Association
  • The Japanese Society of Internal Medicine
Educational
Educational Activities
Mentoring PhD students