Kyushu University Academic Staff Educational and Research Activities Database
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Chiharu Ishii Last modified date:2021.06.20



Graduate School


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Homepage
https://kyushu-u.pure.elsevier.com/en/persons/chiharu-ishii
 Reseacher Profiling Tool Kyushu University Pure
Phone
092-642-6598
Fax
092-642-6598
Academic Degree
Doctor of Philosophy (Medicinal Sciences)
Country of degree conferring institution (Overseas)
No
Field of Specialization
Analytical chemistry
Total Priod of education and research career in the foreign country
00years00months
Research
Research Interests
  • Screening of new diagnostic markers and therapeutic targets of age-related diseases focusing on isomerization of amino acid residues in proteins
    keyword : Protein, D-Amino acid residues, Multi-dimensional HPLC, MS/MS
    2021.03.
Academic Activities
Reports
1. Chiharu ISHII, Aogu FURUSHO, Chin-Ling HSIEH, Kenji HAMASE, Multi-dimensional high-performance liquid chromatographic determination of chiral amino acids and related compounds in real world samples, Chromatography, 10.15583/jpchrom.2020.004, 2020.02.
Papers
1. Yukiko Shimizu, Chiharu Ishii, Rieko Yanobu-Takanashi, Kenta Nakano, Akio Imaike, Masashi Mita, Kenji Hamase, Tadashi Okamura, D-Amino acid oxidase deficiency is caused by a large deletion in the Dao gene in LEA rats, Biochim. Biophys. Acta-Proteins and Proteomics, 10.1016/j.bbapap.2020.140463, 2020.06.
2. Chiharu ISHII, Takeyuki AKITA, Masanobu NAGANO, Masashi MITA, Kenji HAMASE, Determination of chiral amino acids in various fermented products using a two-dimensional HPLC-MS/MS system, Chromatography, 10.15583/jpchrom.2019.011, 2019.03.
3. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development of an online two-dimensional high-performance liquid chromatographic system in combination with tandem mass spectrometric detection for enantiomeric analysis of free amino acids in human physiological fluid, Journal of Chromatography A, 10.1016/j.chroma.2018.07.076, 1570, 91-98, 2018.07.
4. Chiharu ISHII, Tetsuya MIYAMOTO, Shoto ISHIGO, Yurika MIYOSHI, Masashi MITA, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Two-dimensional HPLC-MS/MS determination of multiple D-amino acid residues in the proteins stored under various pH conditions, Chromatography, 10.15583/jpchrom.2017.009, 38, 65-72, 2017.05.
Presentations
1. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Two-Dimensional HPLC-MS/MS Determination of Intrinsic Chiral Amino Acids in the Plasma of Mammals with Various D-Amino Acid Oxidase Activities, 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2019.12.
2. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development of a highly selective two-dimensional HPLC-MS/MS system for the screening of intrinsic D-amino acids in human clinical samples, 30th International Symposium on Pharmaceutical and Biomedical Analysis, 2019.09.
3. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Kenji HAMASE, Determination of D-amino acids in fermented products using an automated two-dimensional HPLC-MS/MS system, 35th International Annual Meeting in Pharmaceutical Sciences, 2019.03.
4. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Development and validation of an on-line two-dimensional HPLC-MS/MS system for the determination of intrinsic chiral amino acids in human physiological fluids, 29th International Symposium on Pharmaceutical and Biomedical Analysis, 2018.09.
5. Chiharu ISHII, Takeyuki AKITA, Masashi MITA, Tomomi IDE, Kenji HAMASE, Selective screening of free D-amino acids in the physiological fluids and D-form residues in the proteins using an automated two-dimensional HPLC-MS/MS system, 2018 Sino-Japanese joint symposium on separation sciences, 2018.07.
6. Chiharu ISHII, Masashi MITA, Takeyuki AKITA, Tomomi IDE, Kenji HAMASE, Development of a fully automated two-dimensional HPLC-MS/MS system for the determination of amino acid enantiomers in human physiological fluids and fermented beverages, 34th International Annual Meeting in Pharmaceutical Sciences, 2018.03.
7. Chiharu ISHII, Tetsuya MIYAMOTO, Shoto ISHIGO, Masashi MITA, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Accumulation of D-amino acid residues in various proteins during storage, 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2017.06.
8. Chiharu ISHII, Shoto ISHIGO, Tetsuya MIYAMOTO, Yurika MIYOSHI, Masashi MITA, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE, Determination of D-amino acid residues in proteins stored under various pH conditions, 27th International Symposium on Pharmaceutical and Biomedical Analysis, 2016.11.